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909 results on '"Ichinohe T"'

65. P605Lower body mass index in patients with acute heart failure is independently associated with higher mortality and hospitalization by dehydration in community-based registry; KICKOFF Registry

Author

Ikuta, A., primary, Takabayashi, K., additional, Okazaki, Y., additional, Ogami, M., additional, Ichinohe, T., additional, Yamamoto, T., additional, Hujita, R., additional, Takenaka, H., additional, Haruna, Y., additional, Kitaguchi, S., additional, and Nohara, R., additional

Published
2017
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71. Low-dose thymoglobulin as second-line treatment for steroid-resistant acute GvHD: an analysis of the JSHCT

Author

Murata, M, primary, Ikegame, K, additional, Morishita, Y, additional, Ogawa, H, additional, Kaida, K, additional, Nakamae, H, additional, Ikeda, T, additional, Nishida, T, additional, Inoue, M, additional, Eto, T, additional, Kubo, K, additional, Sakura, T, additional, Mori, T, additional, Uchida, N, additional, Ashida, T, additional, Matsuhashi, Y, additional, Miyazaki, Y, additional, Ichinohe, T, additional, Atsuta, Y, additional, and Teshima, T, additional

Published
2016
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73. Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: Incidence, risk factors and outcomes

Author

Yakushijin, K, primary, Atsuta, Y, additional, Doki, N, additional, Yokota, A, additional, Kanamori, H, additional, Miyamoto, T, additional, Ohwada, C, additional, Miyamura, K, additional, Nawa, Y, additional, Kurokawa, M, additional, Mizuno, I, additional, Mori, T, additional, Onizuka, M, additional, Taguchi, J, additional, Ichinohe, T, additional, Yabe, H, additional, Morishima, Y, additional, Kato, K, additional, Suzuki, R, additional, and Fukuda, T, additional

Published
2015
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77. Comparative study on anesthetic potency depending on concentrations of lidocaine and epinephrine: assessment of dental local anesthetics using the jaw-opening reflex

Author

Ohkado, S., Ichinohe, T., and Kaneko, Y.

Subjects
Male, Dose-Response Relationship, Drug, Epinephrine, Electromyography, Anesthesia, Dental, Lidocaine, Electric Stimulation, Neck Muscles, Reflex, Linear Models, Animals, Vasoconstrictor Agents, Rabbits, Anesthetics, Local, Dental Pulp, Research Article, Probability
Abstract

Anesthetic potency of a local anesthetic on the dental pulp was investigated by increasing or decreasing the concentration of lidocaine and that of epinephrine. An electromyogram of the digastric muscle in Japan White male rabbits was recorded during the jaw-opening reflex induced by electrical stimulation of the dental pulp. Probit analysis was used for the determination of the 50% effective volume (ED50) values of the anesthetic. The anesthetics used were plain 2% lidocaine solution (2Lid-0 group), 2% lidocaine solution with 12.5 microgram/mL of epinephrine (2Lid-1/8 group), 2% lidocaine solution with 6.25 microgram/mL of epinephrine (2Lid-1/16 group), and 4% lidocaine solution with 5 microgram/mL of epinephrine (4Lid-1/20 group). No anesthetic effect was shown in the 2Lid-0 group. The 2Lid-1/8 group indicated adequate anesthetic potency with the smallest dosage at all observation periods. The potency in the 2Lid-1/16 group was 0.3-0.5 times, and that in the 4Lid-1/20 group was 0.3-0.4 times as much as the 2Lid-1/8 group. The decrease in epinephrine concentration produced the decrease in the anesthetic potency on the dental pulp independent of lidocaine concentration. These results suggest that the increase in lidocaine concentration may not compensate the decrease in epinephrine concentration.

Published
2001

78. Preemptive effects of a combination of preoperative diclofenac, butorphanol, and lidocaine on postoperative pain management following orthognathic surgery

Author

Nagatsuka, C., Ichinohe, T., and Kaneko, Y.

Subjects
Adult, Male, Diclofenac, Mandibular Nerve, Premedication, Statistics as Topic, Drinking, Mandible, Retrognathia, Statistics, Nonparametric, Double-Blind Method, Administration, Rectal, Humans, Anesthetics, Local, Pain Measurement, Pain, Postoperative, Anti-Inflammatory Agents, Non-Steroidal, Lidocaine, Nerve Block, Osteotomy, Analgesics, Opioid, Butorphanol, Anesthesia Recovery Period, Injections, Intravenous, Prognathism, Female, Research Article, Follow-Up Studies
Abstract

The aim of the study was to investigate whether preemptive multimodal analgesia (diclofenac, butorphanol, and lidocaine) was obtained during sagittal split ramus osteotomy (SSRO). Following institutional approval and informed consent, 82 healthy patients (ASA-I) undergoing SSRO were randomly assigned to 1 of 2 groups, the preemptive multimodal analgesia group (group P, n = 41) and the control group (group C, n = 41). This study was conducted in a double-blind manner. Patients in group P received 50 mg rectal diclofenac sodium, 10 micrograms/kg intravenous 0.1% butorphanol tartrate, and 1% lidocaine solution containing 10 micrograms/mL epinephrine for regional anesthesia and for bilateral inferior alveolar nerve blocks before the start of surgery. Postoperative pain intensity at rest (POPI) was assessed on a numerical rating score (NRS) in the postanesthesia care unit (PACU) and on a visual analogue scale (VAS) at the first water intake (FWI) and at 24, 48, and 72 hours after extubation. POPI in the PACU was significantly lower in group P than in group C, whereas there were no significant differences at FWI, 24, 48, and 72 hours after extubation in both groups. Preemptive multimodal analgesia was not observed in this study.

Published
2000

79. Pretransplant serum ferritin and C-reactive protein as predictive factors for early bacterial infection after allogeneic hematopoietic cell transplantation.

Author

30636311, 10329401, 80402858, 30378624, 10378630, 30223118, Kanda, J, Mizumoto, C, Ichinohe, T, Kawabata, H, Saito, T, Yamashita, K, Kondo, T, Takakura, S, Ichiyama, S, Uchiyama, T, Ishikawa, T, 30636311, 10329401, 80402858, 30378624, 10378630, 30223118, Kanda, J, Mizumoto, C, Ichinohe, T, Kawabata, H, Saito, T, Yamashita, K, Kondo, T, Takakura, S, Ichiyama, S, Uchiyama, T, and Ishikawa, T

Abstract

Although fluoroquinolones or other antibiotics are commonly used to prevent bacterial infections after hematopoietic cell transplantation (HCT), because of the growing presence of multidrug-resistant microorganisms, it is important to identify patients who are more likely to benefit from antibacterial prophylaxis. To evaluate risk factors for early bacterial infection after allogeneic HCT, we retrospectively analyzed clinical data for 112 consecutive adult patients with hematological malignancies who received transplants without any antibacterial prophylaxis. The cumulative incidence of bacterial infection at 30 days after transplantation was 16%. Among various pre-transplant factors, only high serum ferritin (>700 ng/mL, 47 patients) and high C-reactive protein (CRP) (>0.3 mg/dL, 28 patients) levels were significantly associated with the development of bacterial infection in a multivariate analysis (hazard ratio (95% confidence interval): ferritin, 4.00 (1.32-12.17); CRP, 3.64 (1.44-9.20)). In addition, septic shock and sepsis with organ failure were exclusively observed in patients who had high ferritin and/or high CRP levels. These results suggest that pretransplant serum ferritin and CRP levels can be useful markers for predicting the risk of early bacterial infection after allogeneic HCT. It may be prudent to limit antibacterial prophylaxis to patients with predefined risk factors to ensure the safety of HCT with the use of fewer antibiotics.

Published
2011

80. A case of zoster sine herpete of the trigeminal nerve.

Author

歯科麻酔学, 歯科放射線学, 口健臨・歯科麻酔学, Kasahara, M, Ichinohe, T, Sano, T, Fukuda, K, Kaneko, Y, 歯科麻酔学, 歯科放射線学, 口健臨・歯科麻酔学, Kasahara, M, Ichinohe, T, Sano, T, Fukuda, K, and Kaneko, Y

Published
2011

83. Association between tissue characteristics evaluated with optical coherence tomography and mid-term results after paclitaxel-coated balloon dilatation for in-stent restenosis lesions: a comparison with plain old balloon angioplasty

Author

Tada, T., primary, Kadota, K., additional, Hosogi, S., additional, Miyake, K., additional, Amano, H., additional, Nakamura, M., additional, Izawa, Y., additional, Kubo, S., additional, Ichinohe, T., additional, Hyoudou, Y., additional, Eguchi, H., additional, Hayakawa, Y., additional, Otsuru, S., additional, Hasegawa, D., additional, Shigemoto, Y., additional, Habara, S., additional, Tanaka, H., additional, Fuku, Y., additional, Kato, H., additional, Goto, T., additional, and Mitsudo, K., additional

Published
2013
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85. Epinephrine at doses used in dentistry deteriorates platelet retention rate

Author

Ichinohe, T., Fukuda, K., and Kaneko, Y.

Subjects
Adult, Male, Dose-Response Relationship, Drug, Epinephrine, Platelet Aggregation, Oral Surgical Procedures, Humans, Vasoconstrictor Agents, Female, Middle Aged, Research Article, Aged
Abstract

Epinephrine promotes platelet aggregation through alpha 2 receptor-mediated mechanisms. In this study, the change in the platelet retention rate (PRR) was investigated before and after submucosal epinephrine injection with or without lidocaine in oral surgical patients during isoflurane-nitrous oxide anesthesia. Thirty-nine consenting patients participated in this study. Subjects were allocated in one of five groups depending on the solution injected, the diclofenac supplement, and the patients' age. PRR was measured immediately before and 5 min after epinephrine injection using a modified form of Saltzman's method. Injection of epinephrine with lidocaine deteriorated PRR, although epinephrine without lidocaine produced no PRR change. Epinephrine at doses used in routine dental practices may activate the platelet aggregating function. Dentists should keep in mind that epinephrine elicits both hemodynamic and platelet-activating effects. The latter may be of clinical importance in some situations.

Published
1997

86. Effects of block analgesia on attenuating intraoperative stress responses during oral surgery

Author

Mamiya, H., Ichinohe, T., and Kaneko, Y.

Subjects
Adult, Male, Anesthesia, Dental, Oral Surgical Procedures, Hemodynamics, Nerve Block, Mandible, Osteotomy, Norepinephrine, Stress, Physiological, Humans, Female, Analgesia, Intraoperative Complications, Research Article
Abstract

Surgical intervention affects cardiorespiratory function and deteriorates the homeostatic mechanisms. The aim of this study was to evaluate the effect of block analgesia, which may minimize the intraoperative stress responses during oral surgery. In addition, we evaluated whether block analgesia could lessen the anesthetic requirements. Twenty-eight operative patients were randomly allocated to one of four groups: group 1, 1.3MAC without block analgesia; group 2, 1.6MAC without block analgesia; group 3, 1.0MAC with block analgesia; and group 4, 1.3MAC with block analgesia. Systolic blood pressure (SBP), heart rate (HR), and plasma norepinephrine levels (NE) were measured and compared. Results showed that the increases in SBP, HR, and NE in groups 1 and 2 were greater than those in groups 3 and 4. SBP elevation in group 1 was the greatest among all groups. These results suggest that block analgesia appears to be effective for preventing hyperreactivity of the sympathetic nervous and endocrine systems. In conclusion, general anesthesia combined with block analgesia assures safer anesthesia for patients with cardiovascular diseases or elderly patients who require cardiovascular stability during surgery.

Published
1997

94. Mechanism of NKT cell activation by intranasal coadministration of α-galactosylceramide, which can induce cross-protection against influenza viruses

Author

Kamijuku, H, primary, Nagata, Y, additional, Jiang, X, additional, Ichinohe, T, additional, Tashiro, T, additional, Mori, K, additional, Taniguchi, M, additional, Hase, K, additional, Ohno, H, additional, Shimaoka, T, additional, Yonehara, S, additional, Odagiri, T, additional, Tashiro, M, additional, Sata, T, additional, Hasegawa, H, additional, and Seino, K-i, additional

Published
2008
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