Search

Your search keyword '"Huang, Juntao"' showing total 279 results
Start Over Author "Huang, Juntao"
279 results on '"Huang, Juntao"'

68. Butterfly Cartilage Tympanoplasty as an Alternative to Conventional Surgery for Tympanic Membrane Perforations: A Systematic Review and Meta-Analysis.

Author

Huang, Juntao, Teh, Bing Mei, and Shen, Yi

Subjects
*ONLINE information services, *MEDICAL databases, *META-analysis, *MEDICAL information storage & retrieval systems, *CONFIDENCE intervals, *TYMPANIC membrane perforation, *SYSTEMATIC reviews, *TREATMENT effectiveness, *QUALITATIVE research, *TYMPANOPLASTY, *DESCRIPTIVE statistics, *RESEARCH funding, *MEDLINE, *DATA analysis software, *ODDS ratio
Abstract

Objective: To compare the effectiveness of butterfly cartilage tympanoplasty (BCT) with that of conventional surgical approaches in the treatment of tympanic membrane perforations. Methods: A systematic search was performed by screening the PubMed, Embase, and Cochrane Library databases up to October 31, 2020. Two coauthors independently identified studies in accordance with the selection criteria. Data were pooled and analyzed via Review Manager version 5.3 and Stata version 12.0 software. The postoperative outcomes were measured and expressed as odds ratios (ORs) and standardized mean differences (SMDs). Additionally, heterogeneity was assessed through the I2 statistic. Results: A total of 15 articles were eligible for final inclusion. The OR values for the graft uptake rate, compared to conventional tympanoplasty, were 1.12 (95%CI: 0.56-2.22, I2 = 52%, P =.75) and 1.22 (95%CI: 0.58-2.59, I2 = 0%, P =.60), and the OR compared to fat plug myringoplasty was 3.02 (95%CI: 1.04-8.77, I2 = 0%, P =.04). The qualitative analysis of the hearing results reflected significant postoperative auditory gains with no significant differences between the BCT and control groups, indicating satisfactory and similar postoperative hearing improvement. Moreover, the operation time was shortened (SMD = −2.19, 95%CI: −2.79 to −1.59, I2 = 82%, P <.05), and the postoperative pain was less with the BCT approach. Conclusion: Butterfly cartilage tympanoplasty has satisfactory efficacy in terms of anatomical and functional results in small to medium perforations. It reduces operation time and postoperative pain. However, the effectiveness on large perforation requires further assessment by well-designed studies. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

69. The Novel-Natural-Killer-Cell-Related Gene Signature Predicts the Prognosis and Immune Status of Patients with Hepatocellular Carcinoma.

Author

Li, Minjun, Huang, Juntao, Zhan, Guohua, Li, Yuankuan, Fang, Chunye, and Xiang, Bangde

Subjects
*HEPATOCELLULAR carcinoma, *IMMUNITY, *DISEASE risk factors, *OVERALL survival, *PROGNOSIS, *PROGRESSION-free survival
Abstract

The current understanding of the prognostic significance of natural killer (NK) cells and their tumor microenvironment (TME) in hepatocellular carcinoma (HCC) is limited. Thus, we screened for NK-cell-related genes by single-cell transcriptome data analysis and developed an NK-cell-related gene signature (NKRGS) using multi-regression analyses. Patients in the Cancer Genome Atlas cohort were stratified into high- and low-risk groups according to their median NKRGS risk scores. Overall survival between the risk groups was estimated using the Kaplan–Meier method, and a NKRGS-based nomogram was constructed. Immune infiltration profiles were compared between the risk groups. The NKRGS risk model suggests significantly worse prognoses in patients with high NKRGS risk (p < 0.05). The NKRGS-based nomogram showed good prognostic performance. The immune infiltration analysis revealed that the high-NKRGS-risk patients had significantly lower immune cell infiltration levels (p < 0.05) and were more likely to be in an immunosuppressive state. The enrichment analysis revealed that immune-related and tumor metabolism pathways highly correlated with the prognostic gene signature. In this study, a novel NKRGS was developed to stratify the prognosis of HCC patients. An immunosuppressive TME coincided with the high NKRGS risk among the HCC patients. The higher KLRB1 and DUSP10 expression levels correlated with the patients' favorable survival. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

72. Prognostic Value of Inflammation-Immunity-Nutrition Score and Inflammatory Burden Index for Hepatocellular Carcinoma Patients After Hepatectomy

Author

Song,Rui, Ni,Hanghang, Huang,Juntao, Yang,Chenglei, Qin,Shangdong, Wei,Huaning, Luo,Jiefu, Huang,Yuxiang, Xiang,Bangde, Song,Rui, Ni,Hanghang, Huang,Juntao, Yang,Chenglei, Qin,Shangdong, Wei,Huaning, Luo,Jiefu, Huang,Yuxiang, and Xiang,Bangde

Abstract

Rui Song,1,2,&ast; Hanghang Ni,1,&ast; Juntao Huang,1,&ast; Chenglei Yang,1 Shangdong Qin,1,3 Huaning Wei,1 Jiefu Luo,1 Yuxiang Huang,1 Bangde Xiang1– 3 1Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, People’s Republic of China; 2Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors, Ministry of Education, Nanning, People’s Republic of China; 3Guangxi Liver Cancer Diagnosis and Treatment Engineering and Technology Research Center, Nanning, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Bangde Xiang, Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Qingxiu District, Nanning, Guangxi, 530021, People’s Republic of China, Tel +86-7715301253, Email xiangbangde@gxmu.edu.cnPurpose: The study aimed to investigate the ability of inflammation-immunity-nutrition score (IINS) and inflammatory burden index (IBI), individually or in combination, to predict prognosis of hepatocellular carcinoma (HCC) patients after hepatectomy.Methods: A total of 701 patients who underwent HCC resection at Guangxi Medical University Cancer Hospital were enrolled in the study. An IINS ranging from 0 to 3 was defined based on preoperative C-reactive protein (CRP), lymphocyte count, and serum albumin level, while an IBI was based on CRP and neutrophil-to-lymphocyte ratio. The prognostic value of IINS and IBI was assessed using univariate and multivariate Cox regression and Kaplan–Meier survival curves. The concordance index and calibration curve were used for internal validation of models. Decision curve analysis, net reclassification index and integrated discrimination improvement were used to compare the predictive performance of the models with traditional staging systems.Results: IINS and IBI were able to predict poor prognosis in HCC patients after hepatectomy, and a nomogram based on the IINS predicted su

Published
2022

73. ESPL1 is Elevated in Hepatocellular Carcinoma and Predicts Prognosis

Author

Song,Rui, Huang,Juntao, Yang,Chenglei, Li,Yuankuan, Zhan,Guohua, Xiang,Bangde, Song,Rui, Huang,Juntao, Yang,Chenglei, Li,Yuankuan, Zhan,Guohua, and Xiang,Bangde

Abstract

Rui Song,1,2,&ast; Juntao Huang,1,2,&ast; Chenglei Yang,1,2 Yuankuan Li,1,2 Guohua Zhan,1,2 Bangde Xiang1– 3,&ast; 1Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, People’s Republic of China; 2Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors, Ministry of Education, Nanning, People’s Republic of China; 3Guangxi Liver Cancer Diagnosis and Treatment Engineering and Technology Research Center, Nanning, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Bangde Xiang, Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, 71 Hedi Road, Qingxiu District, Nanning, Guangxi, 530021, People’s Republic of China, Tel +86-7715301253, Email xiangbangde@gxmu.edu.cnPurpose: The extra spindle pole bodies-like 1 (ESPL1) gene is associated with malignant biological behaviors in several tumors. Nevertheless, the correlation between hepatocellular carcinoma (HCC) and ESPL1 has not been determined. The present study analyzed the molecular function and prognostic value of ESPL1 in HCC.Patients and Methods: Samples from 121 HCCs and 119 adjacent normal tissue specimens were subjected to next-generation sequencing. Clinicopathological and genetic data of HCC patients in The Cancer Genome Atlas (TCGA) were also collected. ESPL1 expression was assessed in 20 pairs of HCC and normal liver specimens by qRT-PCR and immunohistochemistry (IHC). The prognostic value of ESPL1 expression was determined by Cox univariate and multivariate regression analyses. ESPL1-related co-expressed genes were evaluated by weighted gene co-expression network analysis (WGCNA). Processes and pathways involving ESPL1 in HCC were determined by Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. The prognostic values of hub genes were determined by joint effect survival analysis.Results: RNA-Seq, RT-qPCR and

Published
2022

74. On the stability of strong-stability-preserving modified Patankar–Runge–Kutta schemes.

Author

Huang, Juntao, Izgin, Thomas, Kopecz, Stefan, Meister, Andreas, and Shu, Chi-Wang

Subjects
*EULER equations, *TRANSPORT equation
Abstract

In this paper, we perform a stability analysis for classes of second and third order accurate strong-stability-preserving modified Patankar–Runge–Kutta (SSPMPRK) schemes, which were introduced in Huang and Shu [J. Sci. Comput.78 (2019) 1811–1839] and Huang et al. [J. Sci. Comput.79 (2019) 1015–1056] and can be used to solve convection equations with stiff source terms, such as reactive Euler equations, with guaranteed positivity under the standard CFL condition due to the convection terms only. The analysis allows us to identify the range of free parameters in these SSPMPRK schemes in order to ensure stability. Numerical experiments are provided to demonstrate the validity of the analysis. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

76. safe threshold rate of indocyanine green retention at 15 minutes after extreme hepatectomy in patients who have remnant liver volume &lt; 40% of the standard volume as well as chronic liver disease, hepatic fibrosis or cirrhosis

Author

gao, junping, primary, lu, zhan, additional, liang, wanqiang, additional, zhang, jie, additional, qin, shangdong, additional, zhao, jingfei, additional, huang, juntao, additional, gong, wenfeng, additional, and xiang, bangde, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results