337 results on '"Honkakoski, Paavo"'
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52. Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions
53. DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene
54. Protein expression and function of organic anion transporters in short-term and long-term cultures of Huh7 human hepatoma cells
55. Novel in Vitro Method Reveals Drugs That Inhibit Organic Solute Transporter Alpha/Beta (OSTα/β)
56. Additional file: Figure S1. of DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
57. Novel in Vitro Method Reveals Drugs That Inhibit Organic Solute Transporter Alpha/Beta (OSTα/β)
58. Functional Characterization of a Novel Variant of the Constitutive Androstane Receptor (CAR, NR1I3)
59. DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
60. Identification of Key Amino Acids that Impact Organic Solute Transporter α/β(OSTα/β)
61. Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells
62. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine
63. Novel in Vitro Method Reveals Drugs That Inhibit Organic Solute Transporter Alpha/Beta (OSTα/β).
64. Regulation of Human Pluripotent Stem Cell-Derived Hepatic Cell Phenotype by Three-Dimensional Hydrogel Models
65. Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
66. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons
67. Direct and Rapid Transcript Analysis Assay for CYP mRNA Expression and Inducibility in Human Primary Hepatocytes
68. Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator
69. An update on the constitutive androstane receptor (CAR)
70. Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes.
71. Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.
72. Molecular Dynamics Simulations for Human CAR Inverse Agonists
73. New in Vitro Tools to Study Human Constitutive Androstane Receptor (CAR) Biology: Discovery and Comparison of Human CAR Inverse Agonists
74. Insights into Ligand-Elicited Activation of Human Constitutive Androstane Receptor Based on Novel Agonists and Three-Dimensional Quantitative Structure−Activity Relationship
75. Ligand Specificity of Constitutive Androstane Receptor as Probed by Induced-Fit Docking and Mutagenesis
76. Synthesis and Evaluation of Estrogen Agonism of Diaryl 4,5-Dihydroisoxazoles, 3-Hydroxyketones, 3-Methoxyketones, and 1,3-Diketones: A Compound Set Forming a 4D Molecular Library
77. The toxicological role and ligand recognition by constitutive androstane receptor CAR
78. Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans
79. Ligand Recognition by Drug-Activated Nuclear Receptors PXR and CAR: Structural, Site-Directed Mutagenesis and Molecular Modeling Studies
80. Teaching the Basics of Nuclear Receptor Action: A Simple Laboratory Exercise Using the Yeast Two-Hybrid Method
81. Amino Acids Important for Ligand Specificity of the Human Constitutive Androstane Receptor
82. Molecular dynamics simulations of the human CAR ligand-binding domain: deciphering the molecular basis for constitutive activity
83. The role of cell cycle on polyplex-mediated gene transfer into a retinal pigment epithelial cell line
84. In Vitro Methods in the Prediction of Kinetics of Drugs: Focus on Drug Metabolism
85. Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer
86. Dual action of oestrogens on the mouse constitutive androstane receptor
87. Molecular Determinants of Steroid Inhibition for the Mouse Constitutive Androstane Receptor
88. Retina-specific gene expression and improved DNA transfection in WERI-Rb1 retinoblastoma cells
89. Modulation of Mouse and Human Phenobarbital-Responsive Enhancer Module by Nuclear Receptors
90. Extracellular Glycosaminoglycans Modify Cellular Trafficking of Lipoplexes and Polyplexes
91. Induction of drug metabolism by nuclear receptor CAR: molecular mechanisms and implications for drug research
92. A lipid carrier with a membrane active component and a small complex size are required for efficient cellular delivery of anti-sense phosphorothioate oligonucleotides
93. Regulation of cytochrome P450 (CYP) genes by nuclear receptors
94. Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents.
95. Peptide−Oligonucleotide Phosphorothioate Conjugates with Membrane Translocation and Nuclear Localization Properties
96. The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene
97. The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene
98. Activation by Diverse Xenochemicals of the 51-Base Pair Phenobarbital-Responsive Enhancer Module in theCYP2B10Gene
99. Molecular Cloning and Characterization of a Novel Nuclear Protein Kinase in Mice
100. Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes
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