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51. Indications for Cardiac Resynchronization Therapy: 2011 Update From the Heart Failure Society of America Guideline Committee

Author

Stevenson, William G., Hernandez, Adrian F., Carson, Peter E., Fang, James C., Katz, Stuart D., Spertus, John A., Sweitzer, Nancy K., Tang, W.H. Wilson, Albert, Nancy M., Butler, Javed, Westlake Canary, Cheryl A., Collins, Sean P., Colvin-Adams, Monica, Ezekowitz, Justin A., Givertz, Michael M., Hershberger, Ray E., Rogers, Joseph G., Teerlink, John R., Walsh, Mary N., Stough, Wendy Gattis, and Starling, Randall C.

Published
2012
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54. Validating an Idiopathic Dilated Cardiomyopathy Diagnosis Using Cardiovascular Magnetic Resonance: The Dilated Cardiomyopathy Precision Medicine Study

Author

Haas, Garrie J., primary, Zareba, Karolina M., additional, Ni, Hanyu, additional, Bello-Pardo, Erika, additional, Huggins, Gordon S., additional, Hershberger, Ray E., additional, Kinnamon, Daniel D., additional, Jordan, Elizabeth, additional, Haas, Garrie J., additional, Fishbein, Daniel P., additional, Gottlieb, Stephen S., additional, Wheeler, Matthew T., additional, Hofmeyer, Mark, additional, Tang, W.H. Wilson, additional, Owens, Anjali T., additional, Moore, Charles K., additional, Jimenez, Javier, additional, Trachtenberg, Barry H., additional, Sweitzer, Nancy K., additional, Shah, Palak, additional, Lowes, Brian D., additional, Stoller, Douglas, additional, Smart, Frank, additional, Morris, Alanna A., additional, Wilcox, Jane E., additional, Katz, Stuart, additional, Pan, Stephen, additional, Ewald, Gregory A., additional, Aaronson, Keith D., additional, Wang, Jessica J., additional, Pamboukian, Salpy, additional, Judge, Daniel P., additional, Kransdorf, Evan P., additional, Garg, Sonia, additional, Desvigne-Nickens, Patrice, additional, Troendle, James, additional, Fu, Yi-Ping, additional, and Hindorff, Lucia, additional

Published
2022
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56. Validating an Idiopathic Dilated Cardiomyopathy Diagnosis Using Cardiovascular Magnetic Resonance: The DCM Precision Medicine Study

Author

Haas, Garrie J., Zareba, Karolina M., Ni, Hanyu, Bello-Pardo, Erika, Huggins, Gordon S., and Hershberger, Ray E.

Subjects
Cardiomyopathy, Dilated, Heart Failure, Male, Magnetic Resonance Spectroscopy, Contrast Media, Magnetic Resonance Imaging, Cine, Gadolinium, Coronary Artery Disease, Middle Aged, Article, Predictive Value of Tests, Humans, Female, Precision Medicine
Abstract

BACKGROUND: Coronary angiography to identify coronary artery disease (CAD) has been foundational to distinguish the etiology of dilated cardiomyopathy (DCM), including the assignment of idiopathic or ischemic cardiomyopathy. Late gadolinium enhancement (LGE) with cardiovascular magnetic resonance (CMR) has emerged as an approach to identify myocardial scar and identify etiology. METHODS: The DCM Precision Medicine Study included patients with left ventricular dilation and dysfunction attributed to idiopathic DCM, after expert clinical review excluded ischemic or other cardiomyopathies. Ischemic cardiomyopathy was defined as CAD with >50% narrowing at angiography of ≥1 epicardial coronary artery. CMR was not required for study inclusion, but in a post hoc analysis of available CMR reports, patterns of LGE were classified as 1) no LGE, 2) ischemic-pattern LGE: subendocardial/transmural, 3) non-ischemic LGE: midmyocardial/epicardial. RESULTS: Of 1,204 idiopathic DCM patients evaluated, 396 (32.9%) had a prior CMR study; of these, 327 (82.6% of 396) had LGE imaging (mean age 46 years; 53.2% male; 55.4% white); 178 of the 327 (54.4%) exhibited LGE, and 156 of the 178 had LGE consistent with idiopathic DCM. The remaining 22 had transmural or subendocardial LGE. Of these 22, coronary angiography was normal (13), showed luminal irregularities (3), a distant thrombus (1), CAD with

Published
2022

59. HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies: This document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA)

Author

Ackerman, Michael J., Priori, Silvia G., Willems, Stephan, Berul, Charles, Brugada, Ramon, Calkins, Hugh, Camm, A. John, Ellinor, Patrick T., Gollob, Michael, Hamilton, Robert, Hershberger, Ray E., Judge, Daniel P., Le Marec, Hervè, McKenna, William J., Schulze-Bahr, Eric, Semsarian, Chris, Towbin, Jeffrey A., Watkins, Hugh, Wilde, Arthur, Wolpert, Christian, and Zipes, Douglas P.

Published
2011
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62. Response to McGurk et al

Author

Gollob, Michael H., primary, Hershberger, Ray E., additional, Gordon, Adam S., additional, Harrison, Steven M., additional, Lee, Kristy, additional, Martin, Christa Lese, additional, and Miller, David T., additional

Published
2022
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64. Colaboradores

Author

Aaronson, Keith D., Ackerman, Michael J., Ades, Philip A., Albert, Christine M., Albert, Michelle A., Alberts, Mark J., Al-Kindi, Sadeer, Anavekar, Nandan S., Attia, Zachi, Babu-Narayan, Sonya V., Baddour, Larry M., Baggish, Aaron L., Merz, C. Noel Bairey, Bakris, George L., Balady, Gary J., Balzer, David T., Beckman, Joshua A., Bers, Donald M., Bhatnagar, Aruni, Bhatt, Deepak L., Biondi, Bernadette, Blankstein, Ron, Bohula, Erin A., Bonaca, Marc P., Bonow, Robert O., Borlaug, Barry A., Bradfield, Jason S., Braunwald, Eugene, Braverman, Alan C., Brush, John E., Jr., Calkins, Hugh, Canty, John M., Jr., Carney, Robert M., Chandrashekhar, Y.S., Chen, Peng-Shen, Chung, Mina K., Cooper, Leslie T., Jr., Creager, Mark A., Cremer, Paul C., Crestanello, Juan A., Curtis, Anne B., Dangas, George D., Daubert, James P., de Lemos, James A., Després, Jean-Pierre, Devries, Stephen, Di Carli, Marcelo F., Dorbala, Sharmila, Dorfman, Adam L., Duncker, Dirk J., Ellenbogen, Kenneth A., Everett, Thomas H., IV, Fang, James C., Felker, G. Michael, Fleg, Jerome L., Fleisher, Lee A., Forman, Daniel E., Freedland, Kenneth E., Friedman, Paul, Gaziano, J. Michael, Gaziano, Thomas A., Genest, Jacques, Gerszten, Robert, Gillam, Linda D., Giudicessi, John R., Giugliano, Robert P., Goldberger, Ary L., Goldberger, Jeffrey J., Goldhaber, Samuel Z., Groh, William J., Gulati, Martha, Hahn, Rebecca Tung, Hasenfuss, Gerd, Herrmann, Howard C., Herrmann, Joerg, Hershberger, Ray E., Ho, Carolyn Y., Hsue, Priscilla Y., Hundley, W. Gregory, Inzucchi, Silvio E., Jacobson, Francine L., Januzzi, James L., Jr., Maddox, Karen E. Joynt, Kalman, Jonathan M., Kapa, Suraj, Kern, Morton J., Kinlay, Scott, Klein, Allan L., Kloner, Robert A., Knowlton, Kirk U., Krieger, Eric V., Krumholz, Harlan M., Kumbhani, Dharam J., Kwong, Raymond Y., Ky, Bonnie, Lam, Carolyn S.P., Larose, Eric, Lasala, John M., Lenihan, Daniel J., Lenze, Eric J., Leon, Martin B., LeWinter, Martin M., Libby, Peter, Lindenfeld, JoAnn, Lindman, Brian R., Mack, Michael J., Madjid, Mohammad, Mann, Douglas L., Maron, Bradley A., Marx, Nikolaus, Mason, Justin C., Maurer, Mathew S., McCullough, Peter A., McGuire, Darren K., McMurray, John, McNally, Elizabeth M., Mehran, Roxana, Miller, John M., Mirvis, David M., Mocumbi, Ana Olga, Mora, Samia, Morady, Fred, Morris, Alanna A., Morrow, David A., Mozaffarian, Dariush, Musunuru, Kiran, Myerburg, Robert J., Natarajan, Pradeep, Nattel, Stanley, Nishimura, Rick A., Nkomo, Vuyisile T., Noseworthy, Peter, O’Gara, Patrick T., Olgin, Jeffrey E., Ommen, Steve R., Otto, Catherine M., Pagani, Francis D., Patton, Kristen K., Pellikka, Patricia A., Piazza, Gregory, Pibarot, Philippe, Poirier, Paul, Prabhakaran, Dorairaj, Rajagopalan, Sanjay, Reardon, Michael J., Redline, Susan, Rezkalla, Shereif, Rich, Michael W., Ridker, Paul M, Roden, Dan M., Ruberg, Frederick L., Sabatine, Marc S., Sanders, Prashanthan, Schermerhorn, Marc, Scirica, Benjamin M., Seto, Arnold H., Shah, Sanjiv J., Shahanavaz, Shabana, Shivkumar, Kalyanam, Silversides, Candice K., Siu, Samuel C., Solomon, Scott D., Sorrentino, Matthew J., Starling, Randall C., Stevenson, William G., Teerlink, John R., Tester, David J., Thomas, Randal Jay, Thompson, Paul D., Tomaselli, Gordon F., Turakhia, Mintu P., Valente, Anne Marie, Vardeny, Orly, Waters, David D., Weitz, Jeffrey I., Wenger, Nanette Kass, Wilson, Walter R., Wu, Justina C., Zeppenfeld, Katja, and Zile, Michael R.

Published
2024
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68. Effectiveness of the Family Heart TalkCommunication Tool in Improving Family Member Screening for Dilated Cardiomyopathy: Results of a Randomized Trial

Author

Kinnamon, Daniel D., Jordan, Elizabeth, Haas, Garrie J., Hofmeyer, Mark, Kransdorf, Evan, Ewald, Gregory A., Morris, Alanna A., Owens, Anjali, Lowes, Brian, Stoller, Douglas, Tang, W.H. Wilson, Garg, Sonia, Trachtenberg, Barry H., Shah, Palak, Pamboukian, Salpy V., Sweitzer, Nancy K., Wheeler, Matthew T., Wilcox, Jane E., Katz, Stuart, Pan, Stephen, Jimenez, Javier, Aaronson, Keith D., Fishbein, Daniel P., Smart, Frank, Wang, Jessica, Gottlieb, Stephen S., Judge, Daniel P., Moore, Charles K., Mead, Jonathan O., Huggins, Gordon S., Ni, Hanyu, Burke, Wylie, and Hershberger, Ray E.

Published
2023
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72. Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death

Author

Walsh, Roddy, primary, Adler, Arnon, additional, Amin, Ahmad S, additional, Abiusi, Emanuela, additional, Care, Melanie, additional, Bikker, Hennie, additional, Amenta, Simona, additional, Feilotter, Harriet, additional, Nannenberg, Eline A, additional, Mazzarotto, Francesco, additional, Trevisan, Valentina, additional, Garcia, John, additional, Hershberger, Ray E, additional, Perez, Marco V, additional, Sturm, Amy C, additional, Ware, James S, additional, Zareba, Wojciech, additional, Novelli, Valeria, additional, Wilde, Arthur A M, additional, and Gollob, Michael H, additional

Published
2021
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73. An International Evidence Based Reappraisal of Genes Associated with Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) using the ClinGen Framework

Author

James, Cynthia A, Jongbloed, Jan D H, Hershberger, Ray E, Morales, Ana, Judge, Daniel P, Syrris, Petros, Pilichou, Kalliopi, Medeiros Domingo, Argelia, Murray, Brittney, Cadrin-Tourigny, Julia, Lekanne Deprez, Ronald, Celeghin, Rudy, Protonotarios, Alexandros, Asatryan, Babken, Brown, Emily, Jordan, Elizabeth, Mcglaughon, Jennifer, Thaxton, Courtney, Kurtz, C Lisa, and van Tintelen, J Peter

Subjects
ClinGen
Published
2021

74. International Evidence Based Reappraisal of Genes Associated with Arrhythmogenic Right Ventricular Cardiomyopathy Using the Clinical Genome Resource Framework

Author

Genetica, Circulatory Health, James, Cynthia A, Jongbloed, Jan D H, Hershberger, Ray E, Morales, Ana, Judge, Daniel P, Syrris, Petros, Pilichou, Kalliopi, Medeiros Domingo, Argelia, Murray, Brittney, Cadrin-Tourigny, Julia, Lekanne Deprez, Ronald, Celeghin, Rudy, Protonotarios, Alexandros, Asatryan, Babken, Brown, Emily, Jordan, Elizabeth, McGlaughon, Jennifer, Thaxton, Courtney, Kurtz, C Lisa, van Tintelen, J Peter, Genetica, Circulatory Health, James, Cynthia A, Jongbloed, Jan D H, Hershberger, Ray E, Morales, Ana, Judge, Daniel P, Syrris, Petros, Pilichou, Kalliopi, Medeiros Domingo, Argelia, Murray, Brittney, Cadrin-Tourigny, Julia, Lekanne Deprez, Ronald, Celeghin, Rudy, Protonotarios, Alexandros, Asatryan, Babken, Brown, Emily, Jordan, Elizabeth, McGlaughon, Jennifer, Thaxton, Courtney, Kurtz, C Lisa, and van Tintelen, J Peter

Published
2021

75. Evidence-Based Assessment of Genes in Dilated Cardiomyopathy

Author

Arts-assistenten Kinderen, Genetica, Circulatory Health, Jordan, Elizabeth, Peterson, Laiken, Ai, Tomohiko, Asatryan, Babken, Bronicki, Lucas, Brown, Emily, Celeghin, Rudy, Edwards, Matthew, Fan, Judy, Ingles, Jodie, James, Cynthia A, Jarinova, Olga, Johnson, Renee, Judge, Daniel P, Lahrouchi, Najim, Lekanne Deprez, Ronald H, Lumbers, R Thomas, Mazzarotto, Francesco, Medeiros Domingo, Argelia, Miller, Rebecca L, Morales, Ana, Murray, Brittney, Peters, Stacey, Pilichou, Kalliopi, Protonotarios, Alexandros, Semsarian, Christopher, Shah, Palak, Syrris, Petros, Thaxton, Courtney, van Tintelen, J Peter, Walsh, Roddy, Wang, Jessica, Ware, James, Hershberger, Ray E, Arts-assistenten Kinderen, Genetica, Circulatory Health, Jordan, Elizabeth, Peterson, Laiken, Ai, Tomohiko, Asatryan, Babken, Bronicki, Lucas, Brown, Emily, Celeghin, Rudy, Edwards, Matthew, Fan, Judy, Ingles, Jodie, James, Cynthia A, Jarinova, Olga, Johnson, Renee, Judge, Daniel P, Lahrouchi, Najim, Lekanne Deprez, Ronald H, Lumbers, R Thomas, Mazzarotto, Francesco, Medeiros Domingo, Argelia, Miller, Rebecca L, Morales, Ana, Murray, Brittney, Peters, Stacey, Pilichou, Kalliopi, Protonotarios, Alexandros, Semsarian, Christopher, Shah, Palak, Syrris, Petros, Thaxton, Courtney, van Tintelen, J Peter, Walsh, Roddy, Wang, Jessica, Ware, James, and Hershberger, Ray E

Published
2021

78. International Evidence Based Reappraisal of Genes Associated With Arrhythmogenic Right Ventricular Cardiomyopathy Using the Clinical Genome Resource Framework

Author

James, Cynthia A., primary, Jongbloed, Jan D.H., additional, Hershberger, Ray E., additional, Morales, Ana, additional, Judge, Daniel P., additional, Syrris, Petros, additional, Pilichou, Kalliopi, additional, Domingo, Argelia Medeiros, additional, Murray, Brittney, additional, Cadrin-Tourigny, Julia, additional, Lekanne Deprez, Ronald, additional, Celeghin, Rudy, additional, Protonotarios, Alexandros, additional, Asatryan, Babken, additional, Brown, Emily, additional, Jordan, Elizabeth, additional, McGlaughon, Jennifer, additional, Thaxton, Courtney, additional, Kurtz, C. Lisa, additional, and van Tintelen, J. Peter, additional

Published
2021
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80. 2021 ACC/AHA Key Data Elements and Definitions for Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Data Standards (Writing Committee to Develop Clinical Data Standards for Heart Failure)

Author

Bozkurt, Biykem, primary, Hershberger, Ray E., additional, Butler, Javed, additional, Grady, Kathleen L., additional, Heidenreich, Paul A., additional, Isler, Maria Lizza, additional, Kirklin, James K., additional, and Weintraub, William S., additional

Published
2021
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82. Cardiac magnetic resonance imaging of myocardial contrast uptake and blood flow in patients affected with idiopathic or familial dilated cardiomyopathy

Author

Jerosch-Herold, Michael, Sheridan, David C., Kushner, Jessica D., Nauman, Deirdre, Burgess, Donna, Dutton, Diana, Alharethi, Rami, Li, Duanxiang, and Hershberger, Ray E.

Subjects
Magnetic resonance imaging -- Methods, Heart muscle -- Medical examination, Blood flow -- Observations, Blood flow -- Measurement, Cardiomyopathy -- Development and progression, Cardiomyopathy -- Diagnosis, Heart diseases -- Development and progression, Heart diseases -- Diagnosis, Biological sciences
Abstract

Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular (LV) enlargement with systolic dysfunction, other causes excluded. When inherited, it represents familial dilated cardiomyopathy (FDC). We hypothesized that IDC or FDC would show with cardiac magnetic resonance (CMR) increased myocardial accumulation of gadolinium contrast at steady state and decreased baseline myocardial blood flow (MBF) due to structural alterations of the extracellular matrix compared with normal myocardium. CMR was performed in nine persons affected with IDC/FDC. Healthy controls came from the general population (n = 6) or were unaffected family members of FDC patients (n = 3) without signs or symptoms of IDC/FDC or any structural cardiac abnormalities. The myocardial partition coefficient for gadolinium contrast ([[lambda].sub.Gd]) was determined by T1 measurements. LV shape and function and MBF were assessed by standard CMR methods. [[lambda].sub.Gd] was elevated in IDC/FDC patients vs. healthy controls ([[lambda].sub.Gd] = 0.56 [+ or -] 0.15 vs. 0.41 [+ or -] 0.06; P = 0.002), and correlated with LV enlargement (r = 0.61 for [[lambda].sub.Gd] vs. end-diastolic volume indexed by height; P < 0.0l) and with ejection fraction (r = -0.80; P < 0.001). The extracellular volume fraction was higher in IDC patients than in healthy controls (0.31 [+ or -] 0.05 vs. 0.24 [+ or -] 0.03; P = 0.002). Resting MBF was lower in IDC patients (0.64 [+ or -] 0.13 vs. 0.91 [+ or -] 0.22; P = 0.01) than unaffected controls and correlated with both the partition coefficient (r = -0.57; P = 0.012) and the extracellular volume fraction (r = -0.56; P = 0.019). The expansion of the extracellular space correlated with reduced MBF and ventricular dilation. Expansion of the extracellular matrix may be a key contributor to contractile dysfunction in IDC patients. idiopathic dilated cardiomyopathy; partition coefficient; myocardial blood flow

Published
2008

84. Variant Interpretation for Dilated Cardiomyopathy (DCM): Refinement of the ACMG/ClinGen Guidelines for the DCM Precision Medicine Study

Author

Morales, Ana, Kinnamon, Daniel D., Jordan, Elizabeth, Platt, Julia, Vatta, Matteo, Dorschner, Michael O., Starkey, Carl, Mead, Jonathan, Ai, Tomohiko, Burke, Wylie, Gastier-Foster, Julie, Jarvik, Gail P., Rehm, Heidi L., Nickerson, Deborah A., and Hershberger, Ray E.

Subjects
Cardiomyopathy, Dilated, Genetics, Medical, Mutation, Practice Guidelines as Topic, Genetic Variation, Humans, Genetic Predisposition to Disease, Genetic Testing, Genomics, Precision Medicine, Article, United States
Abstract

BACKGROUND -: The hypothesis of the Dilated Cardiomyopathy (DCM) Precision Medicine Study is that most DCM has a genetic basis. The study returns results to probands, and when indicated, to relatives. While both the American College of Medical Genetics and Genomics/Association for Molecular Pathology and ClinGen’s MYH7-cardiomyopathy specifications provide relevant guidance for variant interpretation, further gene and disease specific considerations were required for DCM. To this end, we tailored the ClinGen MYH7-cardiomyopathy variant interpretation framework; the specifications implemented for the study are presented here. METHODS -: Modifications were created and approved by an external Variant Adjudication Oversight Committee. After a pilot using 81 probands, further adjustments were made, resulting in 27 criteria (9 modifications of the ClinGen MYH7 framework and reintroduction of two ACMG/AMP criteria that were deemed not applicable by the ClinGen MYH7 working group). RESULTS -: These criteria were applied to 2,059 variants in a test set of 97 probands. Variants were classified as benign (n=1,702), likely benign (n=33), uncertain significance (n=71), likely pathogenic (LP; n=12), and pathogenic (P; n=3). Only 2/15 LP/P variants were identified in Non-Hispanic African ancestry probands. CONCLUSIONS –: We tailored the ClinGen MYH7 criteria for our study. Our preliminary data show that 15/97 (15.5%) probands have LP/P variants, most of which were identified in probands of Non-Hispanic European ancestry. We anticipate continued evolution of our approach, one that will be informed by new insights on variant interpretation and a greater understanding of the genetic architecture of DCM. CLINICAL TRIAL REGISTRATION -: clinicaltrials.gov; NCT03037632

Published
2020

86. Mutations of presenilin genes in dilated cardiomyopathy and heart failure

Author

Duanxiang Li, Parks, Sharie B., Kushner, Jessica D., Nauman, Deirdre, Burgess, Donna, Ludwigsen, Susan, Partain, Julie, Nixon, Randal R., Allen, Charles N., Irwin, Robert P., Jakobs, Petra M., Litt, Michael, and Hershberger, Ray E.

Subjects
Cardiomyopathy, Dilated -- Genetic aspects, Alzheimer's disease -- Genetic aspects, Gene mutations -- Research, Biological sciences
Abstract

The roles of presenilins mutations on dilated cardiomyopathy (DCM) and heart failure are examined. The results have shown that presenilin 1 (PSEN1) and presenilin 2 (PSEN2) mutations are associated with DCM and heart failure and have implicated novel implications of myocardial disease.

Published
2006

87. Daclizumab to prevent rejection after cardiac transplantation

Author

Hershberger, Ray E., Eisen, Howard J., Starling, Randall C., Bergh, Claes-Hakan, Kormos, Robert L., Love, Robert B., Bakel, Adrian Van, Gordon, Robert D., Popat, Rina, Cockey, Louise, and Mamelok, Richard D.

Subjects
Graft rejection -- Drug therapy, Cardiac patients -- Drug therapy
Abstract

A muticenter, placebo-controlled, double-blind study to confirm the results in daclizumab, a humanized monoclonal antibody against the interleukin-2 receptor, is conducted. The conclusions indicate that daclizumab was efficacious as prophylaxis against acute cellular rejection after cardiac transplantation.

Published
2005

95. An Evidence-based Assessment of Genes in Dilated Cardiomyopathy

Author

Jordan, Elizabeth, primary, Peterson, Laiken, additional, Ai, Tomohiko, additional, Asatryan, Babken, additional, Bronicki, Lucas, additional, Brown, Emily, additional, Celeghin, Rudy, additional, Edwards, Matthew, additional, Fan, Judy, additional, Ingles, Jodie, additional, James, Cynthia A, additional, Jarinova, Olga, additional, Johnson, Renee, additional, Judge, Daniel P, additional, Lahrouchi, Najim, additional, Deprez, Ronald Lekanne, additional, Lumbers, R Thomas, additional, Mazzarotto, Francesco, additional, Domingo, Argelia Medeiros, additional, Miller, Rebecca, additional, Morales, Ana, additional, Murray, Brittney, additional, Peters, Stacey, additional, Pilichou, Kalliopi, additional, Protonotarios, Alexandros, additional, Semsarian, Christopher, additional, Shah, Palak, additional, Syrris, Petros, additional, Thaxton, Courtney, additional, van Tintelen, J Peter, additional, Walsh, Roddy, additional, Wang, Jessica, additional, Ware, James, additional, and Hershberger, Ray E, additional

Published
2020
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98. Novel heterozygous truncating titin variants affecting the A‐band are associated with cardiomyopathy and myopathy/muscular dystrophy

Author

Rich, Kelly A., primary, Moscarello, Tia, additional, Siskind, Carly, additional, Brock, Guy, additional, Tan, Christopher A., additional, Vatta, Matteo, additional, Winder, Thomas L., additional, Elsheikh, Bakri, additional, Vicini, Leah, additional, Tucker, Brianna, additional, Palettas, Marilly, additional, Hershberger, Ray E., additional, Kissel, John T., additional, Morales, Ana, additional, and Roggenbuck, Jennifer, additional

Published
2020
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99. SOS1 Gain-of-Function Variants in Dilated Cardiomyopathy

Author

Cowan, Jason R., primary, Salyer, Lorien, additional, Wright, Nathan T., additional, Kinnamon, Daniel D., additional, Amaya, Pedro, additional, Jordan, Elizabeth, additional, Bamshad, Michael J., additional, Nickerson, Deborah A., additional, and Hershberger, Ray E., additional

Published
2020
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100. Effects of danicamtiv, a novel cardiac myosin activator, in heart failure with reduced ejection fraction: experimental data and clinical results from a phase 2a trial

Author

Voors, Adriaan A., primary, Tamby, Jean‐François, additional, Cleland, John G., additional, Koren, Michael, additional, Forgosh, Leslie B., additional, Gupta, Dinesh, additional, Lund, Lars H., additional, Camacho, Albert, additional, Karra, Ravi, additional, Swart, Henk P., additional, Pellicori, Pierpaolo, additional, Wagner, Frank, additional, Hershberger, Ray E., additional, Prasad, Narayana, additional, Anderson, Robert, additional, Anto, Anu, additional, Bell, Kaylyn, additional, Edelberg, Jay M., additional, Fang, Liang, additional, Henze, Marcus, additional, Kelly, Cynthia, additional, Kurio, Gregory, additional, Li, Wanying, additional, Wells, Kate, additional, Yang, Chun, additional, Teichman, Sam L., additional, Rio, Carlos L., additional, and Solomon, Scott D., additional

Published
2020
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