51. Exploring the potential of public proteomics data
- Author
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Frode S. Berven, Juan Antonio Vizcaíno, Helge Ræder, Lennart Martens, Harald Barsnes, Attila Csordas, Marc Vaudel, and Kenneth Verheggen
- Subjects
0301 basic medicine ,Proteomics ,PHOSPHORYLATION SITE LOCALIZATION ,Bioinformatics ,Knowledge Bases ,Information Dissemination ,Data analysis ,Review ,Biology ,Reuse ,SHOTGUN PROTEOMICS ,Biochemistry ,03 medical and health sciences ,Databases ,PHOSPHOPROTEOMICS DATA ,PRIDE CONVERTER ,Data standards ,DATA REPOSITORIES ,Animals ,Humans ,Shotgun proteomics ,Good practice ,Databases, Protein ,Molecular Biology ,POSTTRANSLATIONAL MODIFICATIONS ,Biology and Life Sciences ,PROTEIN-CODING GENES ,Computational Biology ,Molecular Sequence Annotation ,Computational proteomics ,Data science ,MASS-SPECTROMETRY DATA ,Data Standard ,Data standard ,030104 developmental biology ,TYRANNOSAURUS-REX ,Transparency (graphic) ,SPECTRAL ARCHIVES ,Protein Processing, Post-Translational - Abstract
In a global effort for scientific transparency, it has become feasible and good practice to share experimental data supporting novel findings. Consequently, the amount of publicly available MS‐based proteomics data has grown substantially in recent years. With some notable exceptions, this extensive material has however largely been left untouched. The time has now come for the proteomics community to utilize this potential gold mine for new discoveries, and uncover its untapped potential. In this review, we provide a brief history of the sharing of proteomics data, showing ways in which publicly available proteomics data are already being (re‐)used, and outline potential future opportunities based on four different usage types: use, reuse, reprocess, and repurpose. We thus aim to assist the proteomics community in stepping up to the challenge, and to make the most of the rapidly increasing amount of public proteomics data. publishedVersion
- Published
- 2015