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234 results on '"He, Yiwei"'

57. A combined predictive model based on radiomics features and clinical factors for disease progression in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy

Author

Yang, Hong, primary, Wang, Lin, additional, Shao, Guoliang, additional, Dong, Baiqiang, additional, Wang, Fang, additional, Wei, Yuguo, additional, Li, Pu, additional, Chen, Haiyan, additional, Chen, Wujie, additional, Zheng, Yao, additional, He, Yiwei, additional, Zhao, Yankun, additional, Du, Xianghui, additional, Sun, Xiaojiang, additional, Wang, Zhun, additional, Wang, Yuezhen, additional, Zhou, Xia, additional, Lai, Xiaojing, additional, Feng, Wei, additional, Shen, Liming, additional, Qiu, Guoqing, additional, Ji, Yongling, additional, Chen, Jianxiang, additional, Jiang, Youhua, additional, Liu, Jinshi, additional, Zeng, Jian, additional, Wang, Changchun, additional, Zhao, Qiang, additional, Yang, Xun, additional, Hu, Xiao, additional, Ma, Honglian, additional, Chen, Qixun, additional, Chen, Ming, additional, Jiang, Haitao, additional, and Xu, Yujin, additional

Published
2022
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60. Mitochondrial DNA haplogroup M7: A predictor of poor prognosis for colorectal cancer patients in Chinese population.

Author

Yan, Zeyu, Yuan, Qing, He, Yiwei, Peng, Fan, Liu, Yang, Zhang, Huanqin, Ji, Xiaoying, He, Xianli, Zhao, Qi, Xing, Jinliang, and Guo, Xu

Abstract

Haplogroups and single‐nucleotide polymorphisms (SNP) of mitochondrial DNA (mtDNA) were associated with the prognosis of many types of cancer patients. However, whether mtDNA haplogroups contribute to clinical outcomes of colorectal cancer (CRC) in Chinese population remains to be determined. In this study, mtDNA of tissue samples from 445 CRC patients from Northwestern China was sequenced to evaluate the association between haplogroup and prognosis. The mtDNA sequencing data of 1015 CRC patients from Southern China were collected for validation. We found patients with mtDNA haplogroup M7 had a significantly higher death risk when compared with patients with other haplogroups in both Northwestern (Hazard ratio [HR] = 3.093, 95% CI = 1.768–5.411, p < 0.001) and Southern (HR = 1.607, 95% CI = 1.050–2.459, p = 0.029) China. Then, a haplogroup M7–based mtSNP classifier was selected by using LASSO Cox regression analysis. A nomogram comprising the mtSNP classifier and clinicopathological variables was developed to predict the prognosis of CRC patients (area under the curve [AUC] 0.735, 95% CI = 0.679–0.791). Furthermore, patients with high‐ and low‐risk scores calculated by the haplogroup M7–based mtSNP classifier exhibited significantly different overall survival (OS) and recurrence‐free survival (RFS) (all p < 0.001). Finally, RNA‐seq and immunohistochemical analyses indicated the poor prognosis of patients with haplogroup M7 may be related to mitochondrial dysfunction and immune abnormalities in CRC tissues. In conclusion, the haplogroup M7 and haplogroup M7–based mtSNP classifier seems to be a practical and reliable prognostic predictor for CRC patients, which provides a potential tool of clinical decision‐making for patients with haplogroup M7 in Chinese population. [ABSTRACT FROM AUTHOR]

Published
2023
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64. Novel Dual-Function Sers Identification Strategy for Preliminary Screening and Accurate Diagnosis of Circulating Tumor Cells

Author

Wu, Aiguo, primary, Zhang, Dinghu, additional, Lin, Jie, additional, Xu, Yanping, additional, Wu, Xiaoxia, additional, Xu, Xiawei, additional, Xie, Yujiao, additional, Pan, Ting, additional, He, Yiwei, additional, Luo, Jun, additional, Zhang, Zhewei, additional, Fan, LinYin, additional, Li, Shunxiang, additional, Chen, Tianxiang, additional, and Shao, Guoliang, additional

Published
2022
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70. GaitSet: Cross-View Gait Recognition Through Utilizing Gait As a Deep Set.

Author

Chao, Hanqing, Wang, Kun, He, Yiwei, Zhang, Junping, and Feng, Jianfeng

Subjects
IDENTIFICATION of the dead, ANGLES, CRIME prevention, SOURCE code
Abstract

Gait is a unique biometric feature that can be recognized at a distance; thus, it has broad applications in crime prevention, forensic identification, and social security. To portray a gait, existing gait recognition methods utilize either a gait template which makes it difficult to preserve temporal information, or a gait sequence that maintains unnecessary sequential constraints and thus loses the flexibility of gait recognition. In this paper, we present a novel perspective that utilizes gait as a deep set, which means that a set of gait frames are integrated by a global-local fused deep network inspired by the way our left- and right-hemisphere processes information to learn information that can be used in identification. Based on this deep set perspective, our method is immune to frame permutations, and can naturally integrate frames from different videos that have been acquired under different scenarios, such as diverse viewing angles, different clothes, or different item-carrying conditions. Experiments show that under normal walking conditions, our single-model method achieves an average rank-1 accuracy of 96.1 percent on the CASIA-B gait dataset and an accuracy of 87.9 percent on the OU-MVLP gait dataset. Under various complex scenarios, our model also exhibits a high level of robustness. It achieves accuracies of 90.8 and 70.3 percent on CASIA-B under bag-carrying and coat-wearing walking conditions respectively, significantly outperforming the best existing methods. Moreover, the proposed method maintains a satisfactory accuracy even when only small numbers of frames are available in the test samples; for example, it achieves 85.0 percent on CASIA-B even when using only 7 frames. The source code has been released at https://github.com/AbnerHqC/GaitSet. [ABSTRACT FROM AUTHOR]

Published
2022
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73. Estimating the reproducibility & transparency of smoking cessation behaviour change interventions (2018-2019)

Author

Loh, Rachel, Michie , Susan, West, Robert, He, Yiwei, and Norris , Emma

Subjects
PsyArXiv|Social and Behavioral Sciences, PsyArXiv|Social and Behavioral Sciences|Health Psychology, bepress|Social and Behavioral Sciences|Psychology|Health Psychology, bepress|Social and Behavioral Sciences, PsyArXiv|Social and Behavioral Sciences|Health Psychology|Health-related Behavior
Abstract

Background: Research activities that promote replication and transparency are crucial in the area of smoking cessation, where tobacco and pharmaceutical companies may have vested interests in the findings of health promotion research. The aim of this study is to assess the transparency and reproducibility of smoking cessation behaviour change interventions. Methods: 100 randomised controlled trial behaviour change intervention papers published 2018-2019 from the Cochrane Tobacco Group Specialised Register of controlled trials. Inclusion criteria were that the studies must be full reports of Randomised Controlled Trials, eligible for use in the parallel Human Behaviour-Change Project. All papers were independently coded by two researchers, with inter-rater reliability of coding calculated using Krippendorff’s alpha. Results: 71% of identified papers were publicly available, with 73% pre-registered in a trial registry. However, sharing of research resources facilitating replication was lower, with 13% providing accessible materials, 7% accessible data and 1% accessible analysis scripts. No papers were described as replication studies. 94% of papers provided a funding source statement, with 80% of all studies being exclusively funded by public organisations. 88% of papers provided a conflict of interest statement, with 27% of all studies reporting conflicts of interest involving pharmaceutical companies, 17% involving private companies and 3% involving tobacco companies. Conclusion: Smoking cessation intervention evaluation reports followed good practices in terms of pre-registration and public availability of finished papers. However, the provision of open data, materials and analysis was extremely uncommon and none were claimed to be replications. Transparency was relatively high, with funding sources and conflicts of interest commonly reported and low levels of reported involvement from private and tobacco companies. Future research can compare this baseline assessment of reproducibility and transparency in the field of smoking cessation behaviour change interventions to assess changes.

Published
2020

74. 基于可见光波段的编码优化消色差衍射透镜设计分析

Author

赵玺竣 Zhao Xijun, 范斌 Fan Bin, 何一苇 He Yiwei, 张豪 Zhang Hao, 郑书培 Zheng Shupei, 钟烁 Zhong Shuo, 雷嘉明 Lei Jiaming, 杨伟 Yang Wei, and 杨虎 Yang Hu

Subjects
Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published
2022

78. A TiO2-based bioprobe enabling excellent SERS activity in the detection of diverse circulating tumor cells.

Author

Xu, Yanping, Lin, Jie, Wu, Xiaoxia, Xu, Xiawei, Zhang, Dinghu, Xie, Yujiao, Pan, Ting, He, Yiwei, Wu, Aiguo, and Shao, Guoliang

Abstract

Circulating tumor cells (CTCs) can be the seeds of tumor metastasis and are closely linked to cancer-related death. Fast and effective detection of CTCs is important for the early diagnosis of cancer and the evaluation of micrometastasis. However, the extreme rarity and heterogeneity of CTCs in peripheral blood make sensitive detection of CTCs a big challenge. In this paper, a TiO2-based surface-enhanced Raman scattering (SERS) bioprobe is reported for the first time with outstanding ultrasensitive specificity, excellent stability of the signal, and good biocompatibility for the detection of CTCs. The TiO2 NPs were encoded with alizarin red (AR) and functionalized with reduced bovine serum protein (rBSA) and folic acid (FA). The limit of detection (LOD) for 4-mercaptobenzoic acid (4-MBA) and AR molecules adsorbed on the TiO2 SERS substrate is 5 × 10−7 M. The designed TiO2-based SERS bioprobe can be effectively utilized in detecting four diverse types of cancer cells in rabbit blood, which shows good sensitivity of the SERS detection technology. Finally, precise targeting of CTCs based on the SERS bioprobe with the function of fluorescence imaging is also confirmed by the fluorescence colouration test. This work offers a novel strategy for CTC detection and the development of non-noble metal semiconductor-based SERS platforms for tumor diagnosis. [ABSTRACT FROM AUTHOR]

Published
2022
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90. Genetic variants in gene and clinical outcomes of resectable non-small-cell lung cancer.

Author

He, Yiwei, Wang, Gang, Wang, Qian, Zhao, Zheng, Gan, Lu, Yang, Shirong, Wang, Yongxing, Guo, Shanshan, An, Jiaze, Zhang, Jian, Zhang, Zhaohui, and Zhou, Feng

Abstract

Background: A series of studies have demonstrated that NPAS2 plays a critical role in the development and progression of several cancers. However, the association between genetic variants in the NPAS2 gene and the clinical outcome of patients with non-small-cell lung cancer (NSCLC) has not been investigated. Methods: Six functional SNPs in NPAS2 were selected and genotyped using the Sequenom iPLEX genotyping system in a cohort of 484 Chinese NSCLC patients undergoing surgery. Multivariate Cox proportional hazards model were used for the prognosis analysis. Results: We found that SNP rs2305158 exhibited a significant association with overall survival of NSCLC patients in the dominant model (hazard ratio [HR]: 0.68; 95% CI: 0.49-0.95; p = 0.02). Lymph node metastasis was significantly associated with increased death risk (HR: 1.73; 95% CI: 1.24-2.40; p = 0.001) in patients with the homozygous wildtype (WW) genotype of rs2305158. However, no significant association was observed between them in patients carrying a heterozygous variant (WV) or homozygous variant (VV) genotype of rs2305158. Finally, in the joint and interaction analysis, the patients carrying homozygous wildtype (WW) genotype and lymph node metastasis from N1 to N3 conferred a significant increased effect on death (HR: 2.29; 95% CI: 1.40-3.76; p = 0.001). Conclusions: Our results suggest that NPAS2 polymorphisms may serve as an independent prognostic marker for NSCLC patients. [ABSTRACT FROM AUTHOR]

Published
2021
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96. Tu1603 Predicting Factors of Delayed Versus Early Definitive ERCP for Stone Clearance in Patients With Common Bile Duct Stone and Acute Cholangitis Managed With Temporary Biliary Stenting

Author

Tang, Raymond S., primary, Lam, Siu Fung, additional, Chan, Pui Y., additional, Tang, Man C., additional, Leung, Wai H., additional, He, Yiwei, additional, Lam, Thomas Y., additional, Ng, Siew C., additional, Chan, Francis K., additional, and Lau, James Y., additional

Published
2016
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