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1,029 results on '"Harrison, Rebecca A."'

52. Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Author

Venneti, Sriram, primary, Kawakibi, Abed Rahman, additional, Ji, Sunjong, additional, Waszak, Sebastian M., additional, Sweha, Stefan R., additional, Mota, Mateus, additional, Pun, Matthew, additional, Deogharkar, Akash, additional, Chung, Chan, additional, Tarapore, Rohinton S., additional, Ramage, Samuel, additional, Chi, Andrew, additional, Wen, Patrick Y., additional, Arrillaga-Romany, Isabel, additional, Batchelor, Tracy T., additional, Butowski, Nicholas A., additional, Sumrall, Ashley, additional, Shonka, Nicole, additional, Harrison, Rebecca A., additional, de Groot, John, additional, Mehta, Minesh, additional, Hall, Matthew D., additional, Daghistani, Doured, additional, Cloughesy, Timothy F., additional, Ellingson, Benjamin M., additional, Beccaria, Kevin, additional, Varlet, Pascale, additional, Kim, Michelle M., additional, Umemura, Yoshie, additional, Garton, Hugh, additional, Franson, Andrea, additional, Schwartz, Jonathan, additional, Jain, Rajan, additional, Kachman, Maureen, additional, Baum, Heidi, additional, Burant, Charles F., additional, Mottl, Sophie L., additional, Cartaxo, Rodrigo T., additional, John, Vishal, additional, Messinger, Dana, additional, Qin, Tingting, additional, Peterson, Erik, additional, Sajjakulnukit, Peter, additional, Ravi, Karthik, additional, Waugh, Alyssa, additional, Walling, Dustin, additional, Ding, Yujie, additional, Xia, Ziyun, additional, Schwendeman, Anna, additional, Hawes, Debra, additional, Yang, Fusheng, additional, Judkins, Alexander R., additional, Wahl, Daniel, additional, Lyssiotis, Costas A., additional, de la Nava, Daniel, additional, Alonso, Marta M., additional, Eze, Augustine, additional, Spitzer, Jasper, additional, Schmidt, Susanne V., additional, Duchatel, Ryan J., additional, Dun, Matthew D., additional, Cain, Jason E., additional, Jiang, Li, additional, Stopka, Sylwia A., additional, Baquer, Gerard, additional, Regan, Michael S., additional, Filbin, Mariella G., additional, Agar, Nathalie Y.R., additional, Zhao, Lili, additional, Kumar-Sinha, Chandan, additional, Mody, Rajen, additional, Chinnaiyan, Arul, additional, Kurokawa, Ryo, additional, Pratt, Drew, additional, Yadav, Viveka N., additional, Grill, Jacques, additional, Kline, Cassie, additional, Mueller, Sabine, additional, Resnick, Adam, additional, Nazarian, Javad, additional, Allen, Joshua E., additional, Odia, Yazmin, additional, Gardner, Sharon L., additional, and Koschmann, Carl, additional

Published
2023
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54. High Proportions of Patients With Advanced HIV Are Antiretroviral Therapy Experienced : Hospitalization Outcomes From 2 Sub-Saharan African Sites

Author

Ousley, Janet, Niyibizi, Aline Aurore, Wanjala, Stephen, Vandenbulcke, Alexandra, Kirubi, Beatrice, Omwoyo, Willis, Price, Janthimala, Salumu, Leon, Szumilin, Elisabeth, Spiers, Sofie, van Cutsem, Gilles, Mashako, Maria, Mangana, Freddy, Moudarichirou, Ramzia, Harrison, Rebecca, Kalwangila, Tony, Lumowo, Gisele, Lambert, Vincent, and Maman, David

Published
2018

61. Impact of the government's restrictions and guidance in relation to 'social distancing' on the lives of ethnic minority populations:A mixed methods study

Author

Saini, Pooja, Porcellato, Lorna, Hunt, Anna, Timpson, Hannah, Harrison, Rebecca, Bigland, Charlotte, Levy, Conan, Brett, Caroline E., Forshaw, Mark, Hope, Vivian, and Team, The Phoenix

Subjects
Covid‐19, ethnic minority, social distancing, government restrictions
Abstract

Background and AimsThe impacts of the COVID-19 pandemic have not been equal, with a disproportionate impact among ethnic minority communities. Structural inequalities in social determinants of health such as housing and employment have contributed to COVID-19's impact on deprived communities, including many ethnic minority communities. To compare (1) how the UK government's “social distancing” restrictions and guidance were perceived and implemented by ethnic minority populations compared to white populations, (2) the impact of restrictions and guidance upon these groups.MethodsAn explanatory sequential mixed methods study incorporated a quantitative survey and qualitative semi-structured interviews to explore individual perceptions and experiences of COVID-19 and the national restrictions. Survey participants (n = 1587) were recruited from North West England; 60 (4%) participants were from ethnic minority communities. Forty-nine interviews were conducted; 19 (39%) participants were from ethnic minority communities. Interviews were transcribed verbatim and analysed using a thematic approach. Data collection was between April and August 2020.ResultsSignificant differences in demographics and household overcrowding were observed between white vs ethnic minority survey respondents, who were also significantly less confident in their knowledge of COVID-19, less likely to be high-risk drinkers, and marginally more likely to have experienced job loss and/or reduced household income. There were no group differences in wellbeing, perceptions, or nonfinancial impacts. Two inter-related themes included: (1) government guidance, incorporating people's knowledge and understanding of the guidance and their confusion/frustration over messaging; (2) the impacts of restrictions on keyworkers, home-schooling, working from home and changes in lifestyle/wellbeing.ConclusionsFurther research is needed on the long-term impacts of COVID-19 on ethnic minority communities. If policy responses to COVID-19 are to benefit ethnic minority communities, there is a need for future studies to consider fundamental societal issues, such as the role of housing and economic disadvantage.

Published
2023

63. Adjuvant interferon-α for the treatment of high-risk melanoma: An individual patient data meta-analysis

Author

Bufalino, Rosaria, Cameron, David, Cascinelli, Natale, Doherty, Valerie, Eggermont, Alexander, Garbe, Claus, Gore, Martin, Hancock, Barry, Harrison, Rebecca, Ives, Natalie, Kirkwood, John, Kressig, Michael, Lee, Sandra, Lorigan, Paul, MacKie, Rona, Markovic, Svetomir N., Marsden, Jerry, Suciu, Stefan, Suman, Vera, Turner, Lesley, Wheatley, Keith, Ives, Natalie J., and Eggermont, Alexander M.M.

Published
2017
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64. Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation.

Author

Garner, Omai B, Aguilar, Hector C, Fulcher, Jennifer A, Levroney, Ernest L, Harrison, Rebecca, Wright, Lacey, Robinson, Lindsey R, Aspericueta, Vanessa, Panico, Maria, Haslam, Stuart M, Morris, Howard R, Dell, Anne, Lee, Benhur, and Baum, Linda G

Subjects
Cells, Cultured, Endothelial Cells, Giant Cells, Humans, Nipah Virus, Henipavirus Infections, Polysaccharides, Galectin 1, Viral Fusion Proteins, Membrane Fusion, Protein Binding, Virus Physiological Phenomena, Cells, Cultured, Virology, Microbiology, Immunology, Medical Microbiology
Abstract

Nipah virus targets human endothelial cells via NiV-F and NiV-G envelope glycoproteins, resulting in endothelial syncytia formation and vascular compromise. Endothelial cells respond to viral infection by releasing innate immune effectors, including galectins, which are secreted proteins that bind to specific glycan ligands on cell surface glycoproteins. We demonstrate that galectin-1 reduces NiV-F mediated fusion of endothelial cells, and that endogenous galectin-1 in endothelial cells is sufficient to inhibit syncytia formation. Galectin-1 regulates NiV-F mediated cell fusion at three distinct points, including retarding maturation of nascent NiV-F, reducing NiV-F lateral mobility on the plasma membrane, and directly inhibiting the conformational change in NiV-F required for triggering fusion. Characterization of the NiV-F N-glycome showed that the critical site for galectin-1 inhibition is rich in glycan structures known to bind galectin-1. These studies identify a unique set of mechanisms for regulating pathophysiology of NiV infection at the level of the target cell.

Published
2010

67. Abstract LB127: VAL-083 in patients with recurrent glioblastoma treated under expanded access program

Author

Kamiya-Matsuoka, Carlos, primary, Weathers, Shiao-Pei, additional, Harrison, Rebecca A., additional, Majd, Nazanin K., additional, Aaroe, Ashley E., additional, Knight, Stephanie, additional, Hanna, Teresa, additional, Gregory, Timothy A., additional, Langlands, John, additional, Brown, Dennis, additional, and Puduvalli, Vinay K., additional

Published
2023
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68. Supplementary Figure 4 from Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial

Author

Weathers, Shiao-Pei, primary, Penas-Prado, Marta, primary, Pei, Be-Lian, primary, Ling, Xiaoyang, primary, Kassab, Cynthia, primary, Banerjee, Pinaki, primary, Bdiwi, Mustafa, primary, Shaim, Hila, primary, Alsuliman, Abdullah, primary, Shanley, Mayra, primary, de Groot, John F., primary, O'Brien, Barbara J., primary, Harrison, Rebecca, primary, Majd, Nazanin, primary, Kamiya-Matsuoka, Carlos, primary, Fuller, Gregory N., primary, Huse, Jason T., primary, Chi, Linda, primary, Rao, Ganesh, primary, Weinberg, Jeffrey S., primary, Lang, Frederick F., primary, Sawaya, Raymond, primary, Shpall, Elizabeth J., primary, Rezvani, Katayoun, primary, and Heimberger, Amy B., primary

Published
2023
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69. Supplementary Figure 3 from Glioblastoma-mediated Immune Dysfunction Limits CMV-specific T Cells and Therapeutic Responses: Results from a Phase I/II Trial

Author

Weathers, Shiao-Pei, primary, Penas-Prado, Marta, primary, Pei, Be-Lian, primary, Ling, Xiaoyang, primary, Kassab, Cynthia, primary, Banerjee, Pinaki, primary, Bdiwi, Mustafa, primary, Shaim, Hila, primary, Alsuliman, Abdullah, primary, Shanley, Mayra, primary, de Groot, John F., primary, O'Brien, Barbara J., primary, Harrison, Rebecca, primary, Majd, Nazanin, primary, Kamiya-Matsuoka, Carlos, primary, Fuller, Gregory N., primary, Huse, Jason T., primary, Chi, Linda, primary, Rao, Ganesh, primary, Weinberg, Jeffrey S., primary, Lang, Frederick F., primary, Sawaya, Raymond, primary, Shpall, Elizabeth J., primary, Rezvani, Katayoun, primary, and Heimberger, Amy B., primary

Published
2023
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70. Supplementary Figure 1 from Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Author

Milicic, Anita, primary, Harrison, Lea-Anne, primary, Goodlad, Robert A., primary, Hardy, Robert G., primary, Nicholson, Anna M., primary, Presz, Michal, primary, Sieber, Oliver, primary, Santander, Sonia, primary, Pringle, James H., primary, Mandir, Nikki, primary, East, Philip, primary, Obszynska, Jolanta, primary, Sanders, Scott, primary, Piazuelo, Elena, primary, Shaw, Jacqui, primary, Harrison, Rebecca, primary, Tomlinson, Ian P., primary, McDonald, Stuart A.C., primary, Wright, Nicholas A., primary, and Jankowski, Janusz A.Z., primary

Published
2023
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71. Data from Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Author

Milicic, Anita, primary, Harrison, Lea-Anne, primary, Goodlad, Robert A., primary, Hardy, Robert G., primary, Nicholson, Anna M., primary, Presz, Michal, primary, Sieber, Oliver, primary, Santander, Sonia, primary, Pringle, James H., primary, Mandir, Nikki, primary, East, Philip, primary, Obszynska, Jolanta, primary, Sanders, Scott, primary, Piazuelo, Elena, primary, Shaw, Jacqui, primary, Harrison, Rebecca, primary, Tomlinson, Ian P., primary, McDonald, Stuart A.C., primary, Wright, Nicholas A., primary, and Jankowski, Janusz A.Z., primary

Published
2023
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72. Supplementary Figure 2 from Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Author

Milicic, Anita, primary, Harrison, Lea-Anne, primary, Goodlad, Robert A., primary, Hardy, Robert G., primary, Nicholson, Anna M., primary, Presz, Michal, primary, Sieber, Oliver, primary, Santander, Sonia, primary, Pringle, James H., primary, Mandir, Nikki, primary, East, Philip, primary, Obszynska, Jolanta, primary, Sanders, Scott, primary, Piazuelo, Elena, primary, Shaw, Jacqui, primary, Harrison, Rebecca, primary, Tomlinson, Ian P., primary, McDonald, Stuart A.C., primary, Wright, Nicholas A., primary, and Jankowski, Janusz A.Z., primary

Published
2023
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73. Supplementary Materials from Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

Author

Milicic, Anita, primary, Harrison, Lea-Anne, primary, Goodlad, Robert A., primary, Hardy, Robert G., primary, Nicholson, Anna M., primary, Presz, Michal, primary, Sieber, Oliver, primary, Santander, Sonia, primary, Pringle, James H., primary, Mandir, Nikki, primary, East, Philip, primary, Obszynska, Jolanta, primary, Sanders, Scott, primary, Piazuelo, Elena, primary, Shaw, Jacqui, primary, Harrison, Rebecca, primary, Tomlinson, Ian P., primary, McDonald, Stuart A.C., primary, Wright, Nicholas A., primary, and Jankowski, Janusz A.Z., primary

Published
2023
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74. Poor outcomes among critically ill HIV-positive patients at hospital discharge and post-discharge in Guinea, Conakry: A retrospective cohort study

Author

Albus, Sebastian Ludwig, primary, Harrison, Rebecca E., additional, Moudachirou, Ramzia, additional, Nanan-N’Zeth, Kassi, additional, Haba, Benoit, additional, Casas, Esther C., additional, Isaakidis, Petros, additional, Diallo, Abdourahimi, additional, Camara, Issiaga, additional, Doumbuya, Marie, additional, Sako, Fode Bangaly, additional, and Cisse, Mohammed, additional

Published
2023
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78. Telephone networks and transactional motherhood in Channel 4’s It’s A Sin

Author

Harrison, Rebecca

Subjects
Cultural Studies, Arts and Humanities (miscellaneous), Education
Abstract

This article offers an analysis of women’s representation in the 2021 Channel 4 series It’s A Sin. Focusing on the show’s narrative and ideological use of the telephone network as a system of transactional care, the article critiques depictions of motherhood and questions the erasure of narratives about experiences of gender, race, sexuality, class and disability in queer communities. By way of textual analysis and histories of communication technologies in the 1980s and 1990s, the article argues that It’s A Sin perpetuates conservative and moralising perspectives on a range of issues, particularly with regard to gender and sexual activity.

Published
2022

81. Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis

Author

Gharahkhani, Puya, Fitzgerald, Rebecca C, Vaughan, Thomas L, Palles, Claire, Gockel, Ines, Tomlinson, Ian, Buas, Matthew F, May, Andrea, Gerges, Christian, Anders, Mario, Becker, Jessica, Kreuser, Nicole, Noder, Tania, Venerito, Marino, Veits, Lothar, Schmidt, Thomas, Manner, Hendrik, Schmidt, Claudia, Hess, Timo, Böhmer, Anne C, Izbicki, Jakob R, Hölscher, Arnulf H, Lang, Hauke, Lorenz, Dietmar, Schumacher, Brigitte, Hackelsberger, Andreas, Mayershofer, Rupert, Pech, Oliver, Vashist, Yogesh, Ott, Katja, Vieth, Michael, Weismüller, Josef, Nöthen, Markus M, Attwood, Stephen, Barr, Hugh, Chegwidden, Laura, de Caestecker, John, Harrison, Rebecca, Love, Sharon B, MacDonald, David, Moayyedi, Paul, Prenen, Hans, Watson, R G Peter, Iyer, Prasad G, Anderson, Lesley A, Bernstein, Leslie, Chow, Wong-Ho, Hardie, Laura J, Lagergren, Jesper, Liu, Geoffrey, Risch, Harvey A, Wu, Anna H, Ye, Weimin, Bird, Nigel C, Shaheen, Nicholas J, Gammon, Marilie D, Corley, Douglas A, Caldas, Carlos, Moebus, Susanne, Knapp, Michael, Peters, Wilbert H M, Neuhaus, Horst, Rösch, Thomas, Ell, Christian, MacGregor, Stuart, Pharoah, Paul, Whiteman, David C, Jankowski, Janusz, and Schumacher, Johannes

Published
2016
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82. Scientific evidence and the toxic tort : a socio-legal study of the issues, expert evidence and judgment in Reay and Hope v. British Nuclear Fuels plc

Author

Harrison, Rebecca Jane

Subjects
340, BNFL, LAWSUITS, EPIDEMIOLOGY, NEOPLASMS, LEGAL ASPECTS, HODGKINS DISEASE, LEUKEMIA, UNITED KINGDOM, UKAEA, DELAYED RADIATION EFFECTS
Abstract

Providing a socio-legal analysis of the issues, expert evidence and judgment in Reay and Hope v BNFL plc., the thesis offers an insight into the complexity of the toxic tort. Starting with an overview of the history of Sellafield, the thesis reflects on the scientific and epidemiological concerns surrounding the link between childhood cancer and nuclear installations. Drawing on scientific knowledge and epistemological considerations, the thesis moves on to the difficulties of verifying causation in science and the problems of establishing causation in law. Outlining the role of the expert witness and scientific expert evidence, the thesis proceeds with a case analysis, before broaching the thorny issue of judicial decision making and in particular, the difference between the 'discovery' and 'justification' process. Moving on to the Judgment in Reay and Hope, attention is given to the potential application of probability theory to the judicial decision making process. Lasting just short of one hundred days and including the testimony of numerous scientific experts, Reay and Hope marked new ground in a number of ways; it was the first personal injury claim to test the concept of genetic damage from radiation; the only time that a Queen's Bench Division Judge had been allocated a full-time judicial assistant; and one of the first trials to endorse a satellite video link for examination of international expert witnesses. As far as judicial management is concerned, the case was a forerunner in having Counsels' Opening Statements in writing in advance of the trial, as well as having written daily submissions of key issues from plaintiffs and defendants upon conclusion of oral evidence. The circumstances that led to the trial relate to events in excess of thirty to forty years ago when the fathers of Dorothy Reay and Viven Hope were employed by the Defendants and their predecessors (the United Kingdom Atomic Energy Authority) as fitters for the Sellafield Plant. Intrinsic to the litigation was whether paternal preconception irradiation caused or materially contributed to a predisposition to cancer leading to Dorothy's death from leukaemia and Vivien Hope's non-Hodgkin's lymphoma. As a consequence of the various statutory provisions, the Plaintiffs did not need to prove negligence on the part of the Defendants. In order to succeed the Plaintiffs had to prove on the balance of probabilities that radiation from Sellafield was a material contributory cause of the Plaintiffs' disease. The fundamental issue therefore was causation. In addition to the case analysis, two pieces of empirical research were conducted for the purposes of this thesis. The first, a Social Survey (consisting of thirty four questions) was circulated to 160 members of the Academy of Experts (quantitative research); the second, a letter, involved written communication with sixty five judges from the Queen's Bench Division of the High Court (qualitative research). Underlying this socio-legal case analysis are fundamental questions with regard to existing legal principles, liability and judicial decision making.

Published
1999

85. Characterization of recurrence patterns and outcomes of medulloblastoma in adults: The University of Texas MD Anderson Cancer Center experience

Author

Gregory, Timothy A, primary, Mastall, Maximilian, additional, Lin, Heather, additional, Hess, Kenneth R, additional, Yuan, Ying, additional, Martin-Bejarano Garcia, Manuela, additional, Fuller, Gregory N, additional, Alfaro, Kristin D, additional, Gule-Monroe, Maria K, additional, Huse, Jason T, additional, Khatua, Soumen, additional, Rao, Ganesh, additional, Sandberg, David I, additional, Wefel, Jeffrey S, additional, Yeboa, Debra N, additional, Paulino, Arnold C, additional, McGovern, Susan L, additional, Zaky, Wafik, additional, Mahajan, Anita, additional, Suki, Dima, additional, Weathers, Shiao-Pei, additional, Harrison, Rebecca A, additional, de Groot, John F, additional, Puduvalli, Vinay K, additional, Penas-Prado, Marta, additional, and Majd, Nazanin K, additional

Published
2023
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87. Diversifying Readers' Advisory

Author

Harrison, Rebecca

Subjects
Public libraries -- Social aspects, Racism -- Social aspects, Library and information science
Abstract

The murder of George Floyd in May 2020 and the racial unrest that followed precipitated a seismic shift in Tulsa, Oklahoma, and the rest of the United States. At this [...]

Published
2022

93. Introduction

Author

Harrison, Rebecca L. and Hipchen, Emily

Published
2013

94. Acknowledgments

Author

Harrison, Rebecca L. and Hipchen, Emily

Published
2013

98. Cover

Author

Harrison, Rebecca L. and Hipchen, Emily

Published
2013

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