1,325 results on '"Gupta, Ranjan"'
Search Results
52. Nitrogen Nutrition-Induced Changes in Macronutrient Content and Their Indirect Effect on N-Metabolism Via an Impact on Key N-Assimilating Enzymes in Bread Wheat (Triticum aestivum L.).
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Vandna, Sharma, Vasundhara, Usha, Kalidindi, Singh, Dalveer, Gupta, Ranjan, Gupta, V. K., and Singh, Bhupinder
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GREENHOUSE gases ,SUSTAINABLE agriculture ,GROUNDWATER pollution ,NITROGEN deficiency ,AGRICULTURAL productivity - Abstract
Judicious application of nitrogen (N) fertilizers in crop production is critical for reducing the nitrate pollution of groundwater and greenhouse gas emissions. It is, thus, important to improve the nitrogen use efficiency under the reduced application of nitrogen. A genotypic variation in N-uptake and N-use efficiency particularly under low N-input conditions exists across crops that can be deciphered and exploited for environmentally sustainable farming without any significant penalty of yield and quality. The present research conducted under the nutrient solution culture aimed to explore the inherent variability in the growth response of ten genetically diverse wheat varieties to low fertilizer N-application (N-, 10 µM N) in comparison to N sufficient control (N+, 8.5 mM N) viz., a viz., the activity of various key N-assimilating enzymes and to delineate the indirect effect of low N on uptake and partitioning of other major macronutrients viz., P, K, S, which may indirectly regulate the N-use efficiency. A notable increase in sulfur, potassium, and phosphorus content was observed under nitrogen-deficient conditions. Varieties such as Carnamah and HD 2824 exhibit a significant increase in shoot phosphorus content, emphasizing their potential to optimize phosphorus acquisition and utilization efficiency under nutrient-limited conditions. The findings highlight the complex interplay between nutrient availability and plant responses, showcasing varietal-specific adaptations to nitrogen limitations. [ABSTRACT FROM AUTHOR]
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- 2024
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53. Converging pathways: acquired von Willebrand disease in systemic lupus erythematosus with antiphospholipid antibodies presenting with persistent menstrual bleeding.
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Garg, Ankush, Gupta, Gaurav, Gupta, Ranjan, and Mishra, Ritesh Kumar
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We present a case of a woman in her 20s with inadequately treated systemic lupus erythematosus (SLE). She presented with heavy menstrual bleeding, along with nasal and gum bleeding worsening over 3 months. There was no bleeding history in her family, childhood, dental procedures or childbirth. Evaluation ruled out structural causes, revealing prolonged activated partial thromboplastin time (incomplete correction on mixing studies), normal prothrombin time, moderate thrombocytopenia, and lupus anticoagulant and anti-phosphatidylserine/prothrombin antibody positivity twice, 12 weeks apart. Further evaluation showed very low von Willebrand factor (vWF) levels (<5%). She was treated with pulse methylprednisolone for 3 days, resulting in complete symptom resolution and improvement in vWF levels to 130%. The absence of bleeding history, family history, presence of very low vWF and its response to corticosteroids led to a diagnosis of acquired vWF syndrome as the cause of mucosal bleeding in an SLE patient with concomitant positive antiphospholipid antibody. She was discharged on hydroxychloroquine, mycophenolate mofetil and tapering oral corticosteroids. [ABSTRACT FROM AUTHOR]
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- 2024
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54. Critical peripheral ischemia: Higher prevalence in Indian systemic lupus erythematosus inception cohort for research (INSPIRE).
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Shobha, Vineeta, Rajasekhar, Liza, Manuel, Sandra, V, Nayana, Gupta, Ranjan, Tripathy, Saumya Ranjan, Ghosh, Parasar, Kavadichanda, Chengappa, Mathew, Ashish J, Rathi, Manish, Jain, Avinash, Selvam, Sumitra, and Aggarwal, Amita
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SYSTEMIC lupus erythematosus ,PHOSPHOLIPID antibodies ,GANGRENE ,PULMONARY hypertension ,AUTOANTIBODIES ,ANTIPHOSPHOLIPID syndrome ,LUPUS nephritis - Abstract
Introduction: There is limited literature on digital ischemia in systemic Lupus erythematosus (SLE). We report the prevalence, associations and outcome of digital infarcts and gangrene from the Indian SLE inception cohort (INSPIRE). Methods: From the web-based database of INSPIRE, we extracted information for patients with 'Digital Infarct' and 'Digital gangrene' at enrolment into cohort, together considered as critical peripheral ischemia (CPI); all others were controls. We describe the associations of CPI with SLE clinical phenotype, autoantibodies, and disease activity at enrolment. We also report short term outcomes viz. Digital tissue loss and early mortality up to 6 months and recurrence of digital ischemic events in cases till date. Results: Of 2503 SLE patients enrolled into the INSPIRE cohort, we identified 75 (2.9%) patients with CPI, 72 (96%) women and 6 (8%) children. Of them, 55 (73.3%) had digital gangrene and 21 (28%) patients had digital infarcts. Majority of digital gangrene resulted in amputation distal to terminal phalanx (63.6%). Multivariable analysis showed that pulmonary hypertension AOR [6.34 (1.99, 20.2)], coexistent thrombosis AOR [27.8 (15.7, 48.7)], triple antiphospholipid antibody positivity AOR [5.36 (1.67, 16.9)] and the presence of anti-Scl-70-antibody AOR [5.59 (1.86, 16.7)] were more likely while patients with class 3 or 4 lupus nephritis AOR [0.37 (0.15, 0.95)] and anti-nucleosome antibodies AOR [0.47 (0.23, 0.99)] were less likely to be associated with CPI. SLEDAI and short-term mortality were similar between cases and controls. Conclusions: CPI occurred in a higher proportion (2.9%) of SLE patients in the INSPIRE cohort as compared to earlier reports. Both prothrombotic state and vasculopathy contribute to its occurrence. [ABSTRACT FROM AUTHOR]
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- 2024
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55. Testing the efficiency of metal's market: new evidence from a generalized spectral test
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Pathak, Rajesh, Gupta, Ranjan Das, Taufemback, Cleiton Guollo, and Tiwari, Aviral Kumar
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- 2020
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56. Mechanisms of Penetrating Trauma to the Neck
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Gupta, Ranjan and Nagarkatti, Sushruta
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- 2020
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57. Dopamine transporter availability in alcohol and opioid dependent subjects – a 99mTc-TRODAT-1SPECT imaging and genetic association study
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Grover, Tripti, Gupta, Ranjan, Arora, Geetanjali, Bal, Chandra Shekhar, Ambekar, Atul, Basu Ray, Subrata, Vaswani, Meera, and Sharma, Arundhati
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- 2020
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58. Establishing validity of the fundamentals of spinal surgery (FOSS) simulator as a teaching tool for orthopedic and neurosurgical trainees
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Bhatia, Nitin, Palispis, Winnie A., Urakov, Timur, Gruskay, Jordan, Haghverdian, Justin, Yang, Daniel S., Uong, Jennifer, Albert, Todd, Vaccaro, Alexander, Levi, Allan D., and Gupta, Ranjan
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- 2020
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59. RETRACTED: A preliminary report to discern the association of SNPs rs1505287 and rs4858608 of THRB gene and their haplotype analysis with hypothyroidism and hyperthyroidism among Indian population: a case- control study
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Kaur, Manpreet, primary, Tyagi, Shama, additional, Yadav, Anita, additional, and Gupta, Ranjan, additional
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- 2024
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60. Urinary soluble CD163 is a good biomarker for renal disease activity in lupus nephritis
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Gupta, Ranjan, Yadav, Akhilesh, and Aggarwal, Amita
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- 2021
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61. Comparison of 99mTc-methyl diphosphonate bone scintigraphy and 68Ga-DOTANOC PET/computed tomography in articular manifestation of rheumatoid arthritis
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Shamim, Shamim Ahmed, Arora, Geetanjali, Kumar, Naresh, Behera, Abhishek, Hussain, Jhangir, Gupta, Ranjan, Kumar, Rakesh, and Bal, Chandrasekhar
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- 2022
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62. Substance Dependence: Overview of the Environmental, Genetic, Epigenetic, and Imaging Studies
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Gupta, Ranjan, Sharma, Arundhati, and Paul, Sudip, editor
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- 2019
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63. Interstellar Dust models towards some IUE stars
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Katyal, Nisha, Gupta, Ranjan, and Vaidya, D B
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We study the extinction properties of the composite dust grains, consisting of host silicate spheroids and graphite as inclusions, using discrete dipole approximation (DDA). We calculate the extinction cross sections of the composite grains in the ultraviolet spectral region, 1200\AA -3200\AA and study the variation in extinction as a function of the volume fraction of the inclusions. We compare the model extinction curves with the observed interstellar extinction curves obtained from the data given by the International Ultraviolet Explorer (IUE) satellite. Our results for the composite grains show a distinct variation in the extinction efficiencies with the variation in the volume fraction of the inclusions. In particular, it is found that the wavelength of peak absorption at `2175\AA' shifts towards the longer wavelength with the variation in the volume fraction of inclusions. We find that the composite grain models with the axial ratios viz. 1.33 and 2.0 fit the observed extinction reasonably well with a grain size distribution, a = 0.005-0.250$\mu m$. Moreover, our results of the composite grains clearly indicate that the inhomogeneity in the grain structure, composition and the surrounding media modifies the extinction properties of the grains., Comment: 11 pages, 8 figures, accepted for publication in PASP
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- 2013
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64. Dust properties from GALEX observations of a UV halo around Spica
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Shalima, P., Murthy, Jayant, and Gupta, Ranjan
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
GALEX has detected ultraviolet halos extending as far as 5$^{\circ}$ around four bright stars (Murthy et al. (2011)). These halos are produced by scattering of starlight by dust grains in thin foreground clouds that are not physically associated with the star. Assuming a simple model consisting of a single layer of dust in front of the star, Murthy et al.(2011) have been able to model these halo intensities and constrain the value of the phase function asymmetry factor $g$ of the scattering grains in the FUV and NUV. However due to the uncertainty in the dust geometry they could not constrain the albedo. In this work we have tried to constrain the optical constants and dust geometry by modeling the UV halo of Spica. Since the halo emission is not symmetric, we have modeled the Northern and Southern parts of the halo separately. To the North of Spica, the best-fit albedo is 0.26$\pm$0.1 and $g$ is 0.58$\pm$0.11 in the FUV at the 90% confidence level. The corresponding limits on the distance and optical depth ($\tau$) of the dust sheet is 3.65$\pm$1.05 pc and 0.047$\pm$0.006 respectively. However, owing to a complicated dust distribution to the South of Spica, we were unable to uniquely constrain the dust parameters in that region. Nevertheless, by assuming the optical constants of the Northern region and assuming a denser medium, we were able to constrain the distance of the dust to 9.5$\pm$1.5 pc and the corresponding $\tau$ to 0.04$\pm$0.01., Comment: 4 pages, accepted for publication in Earth, Planets and Space
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- 2013
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65. High-Resolution Near-Infrared Polarimetry of a Circumstellar Disk around UX Tau A
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Tanii, Ryoko, Itoh, Yoichi, Kudo, Tomoyuki, Hioki, Tomonori, Oasa, Yumiko, Gupta, Ranjan, Sen, A. K., Wisniewski, J. P., Muto, T., Grady, C. A., Hashimoto, J., Fukagawa, M., Mayama, S., Hornbeck, J., Sitko, M., Russell, R., Werren, C., Cure, M., Currie, T., Ohashi, N., Okamoto, Y., Momose, M., Honda, M., Inutsuka, S. -I., Takeuchi, T., Dong, R., Abe, L., Brandner, W., Brandt, T., Carson, J., Egner, S., Feldt, M., Fukue, T., Goto, M., Guyon, O., Hayano, Y., Hayashi, M., Hayashi, S. S., Henning, T., Hodapp, K. W., Ishii, M., Iye, M., Janson, M., Kandori, R., Knapp, G. P., Kusakabe, N., Kuzuhara, M., Matsuo, T., McElwain, M. W., Miyama, S., Morino, J. -I., Moro-Martin, A., Nishimura, T., Pyo, T. -S., Serabyn, G., Suto, H., Suzuki, R., Takami, M., Takato, N., Terada, H., Thalmann, C., Tomono, D., Turner, E. L., Watanabe, M., Yamada, T., Takami, H., Usuda, T., and Tamura, M.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present H-band polarimetric imagery of UX Tau A taken with HiCIAO/AO188 on the Subaru Telescope. UX Tau A has been classified as a pre-transitional disk object, with a gap structure separating its inner and outer disks. Our imagery taken with the 0.15 (21 AU) radius coronagraphic mask has revealed a strongly polarized circumstellar disk surrounding UX Tau A which extends to 120 AU, at a spatial resolution of 0.1 (14 AU). It is inclined by 46 \pm 2 degree as the west side is nearest. Although SED modeling and sub-millimeter imagery suggested the presence of a gap in the disk, with the inner edge of the outer disk estimated to be located at 25 - 30 AU, we detect no evidence of a gap at the limit of our inner working angle (23 AU) at the near-infrared wavelength. We attribute the observed strong polarization (up to 66 %) to light scattering by dust grains in the disk. However, neither polarization models of the circumstellar disk based on Rayleigh scattering nor Mie scattering approximations were consistent with the observed azimuthal profile of the polarization degrees of the disk. Instead, a geometric optics model of the disk with nonspherical grains with the radii of 30 micron meter is consistent with the observed profile. We suggest that the dust grains have experienced frequent collisional coagulations and have grown in the circumstellar disk of UX Tau A., Comment: 20 pages, 8 figures, and 1 table. accepted to PASJ
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- 2012
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66. Analytic formulas for frequency and size dependence of absorption and scattering efficiencies of astronomical polycyclic aromatic hydrocarbons
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Roy, Ashim K., Sharma, Subodh K., Gupta, Ranjan, and Ranadive, Pritesh
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Astrophysics - Galaxy Astrophysics - Abstract
In a series of two recent papers, the frequency and size distribution dependence of extinction spectra for astronomical silicate and graphite grains was analyzed by us in the context of MRN type interstellar dust models. These grains were taken to be homogeneous spheres following the power law $(a^{-3.5})$ size distribution which is very much in use. The analytic formulas were obtained for the graphite and silicate grains in wavelength range 1000\AA - 22,500\AA and their utility was demonstrated. In this paper of the series, we present analytic formulas for the scattering and absorption spectrum of another important constituent of interstellar dust models, namely, the polycyclic aromatic hydrocarbons (PAHs). Relative contribution of the PAHs to extinction {\it vis a vis} carbonaceous classical grains has been examined., Comment: 19 pages, 4 figures, to appear in JQSRT 2012
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- 2012
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67. Interstellar Grains: Effect of Inclusions on Extinction
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Katyal, Nisha, Gupta, Ranjan, and Vaidya, D. B.
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Astrophysics - Solar and Stellar Astrophysics - Abstract
A composite dust grain model which simultaneously explains the observed interstellar extinction, polarization, IR emission and the abundance constraints, is required. We present a composite grain model, which is made up of a host silicate oblate spheroid and graphite inclusions. The interstellar extinction curve is evaluated in the spectral region 3.4-0.1$\mu m$ using the extinction efficiencies of the composite spheroidal grains for three axial ratios. Extinction curves are computed using the discrete dipole approximation (DDA). The model curves are subsequently compared with the average observed interstellar extinction curve and with an extinction curve derived from the IUE catalogue data., Comment: 10 pages, 3 figures
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- 2011
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68. Infrared Emission from the Composite Grains: Effects of Inclusions and Porosities on the 10 and 18 $\mu m$ Features
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Vaidya, D. B. and Gupta, Ranjan
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Astrophysics - Solar and Stellar Astrophysics - Abstract
In this paper we study the effects of inclusions and porosities on the emission properties of silicate grains and compare the model curves with the observed infrared emission from circumstellar dust. We calculate the absorption efficiency of the composite grain, made up of a host silicate oblate spheroid and inclusions of ice/graphite/or voids, in the spectral region 5.0-25.0$\mu m$. The absorption efficiencies of the composite spheroidal oblate grains for three axial ratios are computed using the discrete dipole approximation (DDA). We study the absorption as a function of the volume fraction of the inclusions and porosity. In particular, we study the variation in the $10\mu m$ and $18\mu m$ emission features with the volume fraction of the inclusions and porosities. We then calculate the infrared fluxes for these composite grains at several dust temperatures (T=200-350K) and compare the model curves with the average observed IRAS-LRS curve, obtained for circumstellar dust shells around oxygen rich M-type stars. The model curves are also compared with two other individual stars. The results on the composite grains clearly indicate that the silicate feature at 10$\mu m$ shifts with the volume fraction of graphite inclusions. The feature does not shift with the porosity. Both the features do not show any broadening with the inclusions or porosity. The absorption efficiencies of the composite grains calculated using DDA and Effective Medium Approximation (EMA) do not agree. The composite grain models presented in this study need to be compared with the observed IR emission from the circumstellar dust around a few more stars., Comment: 12 pages, 12 figures, 7 tables; To appear in A & A, 2011
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- 2011
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69. Coude-feed stellar spectral library - atmospheric parameters
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Wu, Yue, Singh, Harinder P., Prugniel, Philippe, Gupta, Ranjan, and Koleva, Mina
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Astrophysics - Solar and Stellar Astrophysics - Abstract
Context: Empirical libraries of stellar spectra play an important role in different fields. For example, they are used as reference for the automatic determination of atmospheric parameters, or for building synthetic stellar populations to study galaxies. The CFLIB (Coude-feed library, Indo-US) database is at present one of the most complete libraries, in terms of its coverage of the atmospheric parameters space (Teff, log g and [Fe/H]) and wavelength coverage 3460 - 9464 A at a resolution of 1 A FWHM. Although the atmospheric parameters of most of the stars were determined from detailed analyses of high-resolution spectra, for nearly 300 of the 1273 stars of the library at least one of the three parameters is missing. For the others, the measurements, compiled from the literature, are inhomogeneous. Aims: In this paper, we re-determine the atmospheric parameters, directly using the CFLIB spectra, and compare them to the previous studies. Methods: We use the ULySS program to derive the atmospheric parameters, using the ELODIE library as a reference. Results: Based on comparisons with several previous studies we conclude that our determinations are unbiased. For the 958 F,G, and K type stars the precision on Teff, log g, and [Fe/H] is respectively 43 K, 0.13 dex and 0.05 dex. For the 53 M stars they are 82 K, 0.22 dex and 0.28 dex. And, for the 260 OBA type stars the relative precision on Teff is 5.1%, and on log g, and [Fe/H] the precision is respectively 0.19 dex and 0.16 dex. These parameters will be used to re-calibrate the CFLIB fluxes and to produce synthetic spectra of stellar populations., Comment: 51 pages, accepted for publication in Astronomy and Astrophysics
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- 2010
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70. A CCD photometric study of the newly discovered contact binary ASAS 134738+0410.1
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Deb, Sukanta, Singh, Harinder P., Seshadri, T. R., and Gupta, Ranjan
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present a CCD photometric study of the star with ASAS ID 134738 + 0410.1 using V band observations obtained from the $IUCAA$ Girawali Observatory (IGO) 2-metre telescope, India. The star was selected from the $\delta$ Scuti database of All Sky Automated Survey (ASAS) (Pojmanski 2002). Our analysis reveals that the star is not a $\delta$ Scuti variable but is in fact a W UMa type contact binary with an orbital period of 0.2853067 day. Two new times of primary and secondary minima were determined from the observed data. A preliminary solution obtained using the Wilson-Devinney light curve modelling technique indicates that the star is more likely a partially-eclipsing W UMa type contact binary. However, the determination of actual subtype of this binary is quite impossible from the photometry alone, as the observed light curve can fitted for both A- and W-type solutions. The exact classification of this binary needs to be determined from high resolution spectroscopy., Comment: 7 pages, 2 figures. Accepted for publication in The Bulletin of the Astronomical Society of India (BASI)
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- 2010
71. A CCD photometric study of the late type contact binary EK Comae Berenices
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Deb, Sukanta, Singh, Harinder P., Seshadri, T. R., and Gupta, Ranjan
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Astrophysics - Solar and Stellar Astrophysics - Abstract
We present CCD photometric observations of the W UMa type contact binary EK Comae Berenices using the 2 metre telescope of $IUCAA$ Girawali Observatory, India. The star was classified as a W UMa type binary of subtype-W by \citet{sam1996}. The new V band photometric observations of the star reveal that shape of the light curve has changed significantly from the one observed by \citet{sam1996}. A detailed analysis of the light curve obtained from the high-precision CCD photometric observations of the star indicates that EK Comae Berenices is not a W-type but an A-type totally eclipsing W UMa contact binary. The photometric mass ratio is determined to be 0.349 $\pm$ 0.005. A temperature difference of $\Delta T = 141 \pm 10 $ K between the components and an orbital inclination of $i [^{o}] = 89.800 \pm 0.075$ were obtained for the binary system. Absolute values of masses, radii and luminosities are estimated by means of the standard mass-luminosity relation for zero age main-sequence stars. The star shows O'Connell effect, asymmetries in the light curve shape around the primary and secondary maximum. The observed O'Connell effect is explained by the presence of a hot spot on the primary component., Comment: 26 pages, 9 figures, 5 tables. Accepted for publication in New Astronomy
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- 2010
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72. Topical Tranexamic Acid Does Not Affect Electrophysiologic or Neurovascular Sciatic Nerve Markers in an Animal Model
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Schwarzkopf, Ran, Dang, Phuc, Luu, Michele, Mozaffar, Tahseen, and Gupta, Ranjan
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- 2015
73. Automated star-galaxy segregation using spectral and integrated band data for TAUVEX/ASTROSAT satellite data pipeline
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Bora, Archana, Gupta, Ranjan, Singh, Harinder P., and Duorah, K.
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Astrophysics - Astrophysics of Galaxies - Abstract
We employ an Artificial Neural Network (ANN) based technique to develop a pipeline for automated segregation of stars from the galaxies to be observed by Tel-Aviv University Ultra-Violet Experiment (TAUVEX). We use synthetic spectra of stars from UVBLUE library and selected International Ultraviolet Explorer (IUE) low resolution spectra for galaxies in the ultraviolet (UV) region from 1250 to 3220\AA as the training set and IUE low-resolution spectra for both the stars and the galaxies as the test set. All the data sets have been pre-processed to get band integrated fluxes so as to mimic the observations of the TAUVEX UV imager. We also perform the ANN based segregation scheme using the full length spectral features (which will also be useful for the ASTROSAT mission). Our results suggest that, in the case of the non-availability of full spectral features, the limited band integrated features can be used to segregate the two classes of objects; although the band data classification is less accurate than the full spectral data classification., Comment: 5 pages, 6 figures, To appear in New Astronomy 2009
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- 2009
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74. A study of frequency and size distribution dependence of extinction for astronomical silicate and graphite grains
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Roy, Ashim K., Sharma, Subodh K., and Gupta, Ranjan
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Astrophysics - Galaxy Astrophysics - Abstract
It is generally agreed that interstellar dust grains consist of two main components, namely, silicates and graphites. Some models, like MRN model, assume these grains to be homogeneous spheres following a power law size distribution. This paper presents, in the framework of Mie theory, a parametrization of extinction spectrum curves of the silicates and the graphites separately in terms of frequency and the minimum and maximum of sizes in the distribution. Analytic expressions in ultraviolet and far-ultraviolet are presented for both types of grains.The values of maximum and minimum sizes for which these equations are valid have been identified. These equations can be useful in a number of situations involving silicate and graphite grains., Comment: 19 pages, 5 figures To appear in JQSRT 2009
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- 2009
75. Composite Grains: Effects of Porosity and Inclusions on the 10$\mu$m Silicate Feature
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Vaidya, Deepak B. and Gupta, Ranjan
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Astrophysics - Galaxy Astrophysics - Abstract
We calculate the absorption efficiency of the composite grains, made up of host silicate spheroids and inclusions of ices/graphites/or voids, in the spectral region $7.0-14.0\mu$m The absorption efficiencies of the composite spheroidal grains for three axial ratios are computed using the discrete dipole approximation (DDA) as well as using the effective medium approximation & T-Matrix (EMT-Tmatrix) ap proach. We study the absorption as a function of the volume fraction of the inclusions and porosity. In particular, we study the variation in the $10.0\mu$m feature with the volume fraction of the inclusions and porosity. We then calculate the infrared fluxes for these composite grains and compare the model curves with the average observed IRAS-LRS curve, obtained for several circumstellar dust shells around stars. These results on the composite grains show that the wavelength of the peak absorption shifts and the width of the $10.0\mu$m feature varies with the variation in the volume fraction of the inclusions. The model curves for composite grains with axial ratios not very large (AR$\sim$1.3) and volume fractions of inclusions with f=0.20, and dust temperature of about 250-300$^{\circ}$K, fit the observed emission curves reasonably well., Comment: 14 pages, 6 figures -- to Appear in JQSRT (2009)
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- 2009
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76. A technique to solve mixed strategy non-cooperative zero sum games with more than two players
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Gupta, Ranjan Kumar, primary and Khan, Debdip, additional
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- 2024
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77. Total joint Perioperative Surgical Home: an observational financial review
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Raphael, Darren R, Cannesson, Maxime, Schwarzkopf, Ran, Garson, Leslie M, Vakharia, Shermeen B, Gupta, Ranjan, and Kain, Zeev N
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Clinical Research ,Arthritis ,Health Services ,Good Health and Well Being ,Perioperative surgical home ,Perioperative practice model ,Perioperative care pathway ,Total arthroplasty ,Cost analysis ,Cost variation - Abstract
BackgroundThe numbers of people requiring total arthroplasty is expected to increase substantially over the next two decades. However, increasing costs and new payment models in the USA have created a sustainability gap. Ad hoc interventions have reported marginal cost reduction, but it has become clear that sustainability lies only in complete restructuring of care delivery. The Perioperative Surgical Home (PSH) model, a patient-centered and physician-led multidisciplinary system of coordinated care, was implemented at UC Irvine Health in 2012 for patients undergoing primary elective total knee arthroplasty (TKA) or total hip arthroplasty (THA). This observational study examines the costs associated with this initiative.MethodsThe direct cost of materials and services (excluding professional fees and implants) for a random index sample following the Total Joint-PSH pathway was used to calculate per diem cost. Cost of orthopedic implants was calculated based on audit-verified direct cost data. Operating room and post-anesthesia care unit time-based costs were calculated for each case and analyzed for variation. Benchmark cost data were obtained from literature search. Data are presented as mean ± SD (coefficient of variation) where possible.ResultsTotal per diem cost was $10,042 ± 1,305 (13%) for TKA and $9,952 ± 1,294 (13%) for THA. Literature-reported benchmark per diem cost was $17,588 for TKA and $16,267 for THA. Implant cost was $7,482 ± 4,050 (54%) for TKA and $9869 ± 1,549 (16%) for THA. Total hospital cost was $17,894 ± 4,270 (24%) for TKA and $20,281 ± 2,057 (10%) for THA. In-room to incision time cost was $1,263 ± 100 (8%) for TKA and $1,341 ± 145 (11%) for THA. Surgery time cost was $1,558 ± 290 (19%) for TKA and $1,930 ± 374 (19%) for THA. Post-anesthesia care unit time cost was $507 ± 187 (36%) for TKA and $557 ± 302 (54%) for THA.ConclusionsDirect hospital costs were driven substantially below USA benchmark levels using the Total Joint-PSH pathway. The incremental benefit of each step in the coordinated care pathway is manifested as a lower average length of stay. We identified excessive variation in the cost of implants and post-anesthesia care.
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- 2014
78. Early Surgical Decompression Restores Neurovascular Blood Flow and Ischemic Parameters in an in Vivo Animal Model of Nerve Compression Injury.
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Jung, James, Hahn, Peter, Mozaffar, Tahseen, Choi, Bernard, and Gupta, Ranjan
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Animals ,Biomarkers ,Blotting ,Western ,Catalase ,Decompression ,Surgical ,Disease Models ,Animal ,Hypoxia-Inducible Factor 1 ,alpha Subunit ,Ischemia ,Male ,Matrix Metalloproteinase 9 ,Mice ,Mice ,Inbred C57BL ,Nerve Compression Syndromes ,Neural Conduction ,Peripheral Nerve Injuries ,Sciatic Nerve ,Up-Regulation - Abstract
BACKGROUND: Chronic nerve compression neuropathies result in decreased blood flow at the site of compression. Surgical decompression of the nerve often has variable postoperative results. The current study examines whether the timing of surgical intervention is an important variable in reversing the compression-induced ischemia and associated changes in biochemical markers. METHODS: An established model of chronic nerve compression injury was created in 100 C57BL/6 mice, and serial electrophysiological examinations were used to confirm the creation of a chronic nerve compression injury. Laser speckle imaging was used to measure neural blood flow. Nerves in the animals that did not undergo decompression were harvested at two, four, and six weeks after injury and analyzed for hypoxia-inducible factor 1α (HIF1α), catalase, superoxide dismutase (SOD), and matrix metalloproteinases (MMPs) 2 and 9. Surgical decompression in other animals was performed at either an early (two-week) or late (six-week) time point after injury, with specimens harvested at multiple time points after decompression. One-way analysis of variance with Bonferroni correction was performed. RESULTS: Chronic nerve compression injury initially induced hyperemia (1.37 ± 0.50 times that in the contralateral, uninjured nerve) followed by a decline in neural blood flow by four weeks (0.66 ± 0.14, p = 0.0313). In parallel, HIF1α, catalase, and SOD were elevated early after compression, whereas extracellular matrix-altering proteins were elevated later in the disease. Although early decompression yielded a return of blood flow to a hyperemic state (1.35 ± 0.16, p = 0.0057), late decompression did not result in reversal of the abnormal neurovascular flow. With late decompression, an MMP9-mediated structural alteration of the extracellular matrix was seen, producing irreversible changes in blood flow parameters. Although nerve conduction velocity measurements returned to normal two weeks after decompression irrespective of the timing of the surgical intervention, distal latency returned to normal only after early decompression (0.97 ± 0.06 msec compared with 1.22 ± 0.06 msec for late decompression, p = 0.009). CONCLUSIONS: Chronic nerve compression injuries decreased neurovascular flow and induced ischemia by upregulating HIF1α, catalase, and MMP9. Early surgical intervention offered better return to normal electrophysiological parameters compared with late intervention. CLINICAL RELEVANCE: These data present a clinical correlate to the variable functional outcomes seen following surgical release of chronic nerve compression injuries and provide early support for using distal latency as a predictor of outcomes following surgical release.
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- 2014
79. Association of serotonin and GABA pathway gene polymorphisms with alcohol dependence: A preliminary study
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Sahni, Shweta, Tickoo, Mayanka, Gupta, Ranjan, Vaswani, Meera, Ambekar, Atul, Grover, Tripti, and Sharma, Arundhati
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- 2019
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80. List of Contributors
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Abad, Cantarero, primary, Alexander, Peace, additional, Antonellini, Marco, additional, Arndt, Max, additional, Barbosa, Paola Ferreira, additional, Barik, G.C., additional, Basu, Ananya, additional, Bezerraf, Francisco Hilario R., additional, Bhattacharya, Anindya, additional, Bhattacharya, Aparajita, additional, Billi, Andrea, additional, Biswas, Ankita, additional, Biswas, Tuhin, additional, Bonamici, Chloë, additional, Bontchev, Svetoslav, additional, Bose, Narayan, additional, Buatois, Luis A., additional, Byrne, Paul K., additional, Caine, Jonathan Saul, additional, Calamita, Fernando, additional, Candaux, Zoé, additional, Carola, Eloi, additional, Chagelishvili, Rusudan, additional, Chamyal, L.S., additional, Chatterjee, Sadhana M., additional, Chatterjee, Sreejita, additional, Chetty, T.R.K., additional, Choudhuri, Mainak, additional, Cirillo, D., additional, Compaired, Félix, additional, Cuia, Raffaele Di, additional, Daniel, Muller, additional, Das, Rohini, additional, Das, Sankha, additional, Dasgupta, Sudipta, additional, Dasgupta, Swagato, additional, Deota, Bhushan S., additional, Derez, Tine, additional, Deseta, Natalie, additional, Diraison, Marc, additional, Dutta, Arindam, additional, Dutta, Dripta, additional, Dutta, Shukla, additional, Ellis, Amy, additional, Enukidze, Onise, additional, Fabrizio, Balsamo, additional, Fagereng, Ake, additional, Felipe, Sanchez, additional, Fernández, Carlos, additional, Ferrarini, F., additional, De Filippis, Luigi, additional, Fodor, László, additional, Francesco, Brozzetti, additional, Frassi, Chiara, additional, Gadhavi, M.S., additional, Gazzola, Raffaele, additional, Géraud, Yves, additional, Ghosh, Rajkumar, additional, Gosso, Guido, additional, Goswami, Sukanta, additional, Goswami, Tapos Kumar, additional, Grimmer, Jens Carsten, additional, Gupta, Ranjan, additional, Gupta, Saibal, additional, Heikal, Mohamed Th.S., additional, Hindol, Ghatak, additional, Hokada, Tomokazu, additional, Induni, Guillermo Alvarado, additional, Irene, Cantarero, additional, Izquierdo-Llavall, Esther, additional, James, Hibbard, additional, Jeffrey, Greenberg, additional, Jerry, Magloughlin, additional, Joachim, Place, additional, Johnson, Scott, additional, Jörg, Büchner, additional, Joshi, Aditya, additional, Kar, Eirin, additional, Kar, Rahul, additional, Karanth, R.V., additional, Karaoui, Amar, additional, Karaoui, Brahim, additional, Kázmér, Miklós, additional, Khanal, Subodha, additional, Klimczak, Christian, additional, Koyi, Hemin, additional, Kumar, Samanta Susanta, additional, Lagoeiro, Leonardo Evangelista, additional, Larrovere, Mariano A., additional, Lavecchia, G., additional, Leonardo, Del Sole, additional, Limaye, M.A., additional, Lone, Aasif Mohmad, additional, Lubrano-Lavadera, Paul, additional, Ma, Shengli, additional, Maji, Kankajit, additional, Mancktelow, Neil, additional, Mandal, Subhadip, additional, Maqbool, Yousuf, additional, Marco, Cacador, additional, Marthelot, Jean-Michel, additional, Mathew, George, additional, Maurya, Deepak M., additional, Mazzarini, Francesco, additional, Meere, Patrick, additional, Mery, Biswas, additional, Michele, Fondriest, additional, Michele, Petroccia Alessandro Giovanni, additional, Misra, Achyuta Ayan, additional, Morgan, Perrot, additional, Muhammad, Awais, additional, Mukherjee, Atanu, additional, Mukherjee, Soumyajit, additional, Mulchrone, Kieran F., additional, Musumeci, Giovanni, additional, Naimisha, Vanik, additional, Namrata, Soreng, additional, Narayanan, Shruthi, additional, Navabpour, Payman, additional, Novakova, Lucie, additional, Oliva-Urcia, Belén, additional, Osanai, Yasuhito, additional, Owada, Masaaki, additional, Pace, Paolo, additional, Pal, Dipak C., additional, Pamplona, Jorge Manuel Vieira, additional, Panigrahi, M.K., additional, Paramjeet, Singh, additional, Paul, Jyotirmoy, additional, Pease, Victoria, additional, Pennacchioni, Giorgio, additional, Pinheiro, Roberto Vizeu Lima, additional, Pinto, Suellen Olívia Cândida, additional, Pocoví, Andrés, additional, Pratt, Brian R., additional, Pueyo, Emilio L., additional, Raychaudhuri, Debjani, additional, Rodas, Guido Sibaja, additional, Rodrigues, B.J.C., additional, Rossetti, Federico, additional, Roy, Priyom, additional, Sadhu, Rajib, additional, Sadradze, Nino, additional, Saha, Dilip, additional, Sakawat, Hossain, additional, Salvi, Dnyanada, additional, Samanta, Anupam, additional, Sánchez, Elisa M., additional, Sanjukta, De, additional, Sarkar, Moloy, additional, Sausse, Judith, additional, Schnabl, Petr, additional, Scott, Jennifer J., additional, Sen, Souvik, additional, Sengupta, Sudipta, additional, Shaikh, Mohammedharoon, additional, Sheth, Hetu, additional, Shimamoto, Toshihiko, additional, Shimizu, Ichiko, additional, Shiraishi, Kazuyuki, additional, Simões, Luiz Sérgio Amarante, additional, Simone, Masoch, additional, Singh, Aabha, additional, Singh, Bikramaditya, additional, Singh, Shailendra, additional, Sintubin, Manuel, additional, Soto, Ruth, additional, Strozyk, Frank, additional, Takahashi, Yutaka, additional, Tarun, Solanki, additional, Tavarnelli, Enrico, additional, Togo, Tetsuhiro, additional, Törő, Balázs, additional, Di Toro, Giulio, additional, Toyoshima, Tsuyoshi, additional, Tsunogae, Toshiaki, additional, Urai, Janos L., additional, Victor, Alania, additional, Vignaroli, Gianluca, additional, Virgo, Simon, additional, Vrabec, Marko, additional, Wang, Xin, additional, Yajioui, Zakarya, additional, Yao, Lu, additional, Yehuda, Eyal, additional, Yin, Hongwei, additional, Zhang, Ran, additional, and Zhenyun, Wu, additional
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- 2021
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81. Pattern of disease expression in SLE patients with antiphospholipid antibodies: data from Indian Systemic Lupus Erythematosus Inception cohort (INSPIRE)
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Shobha, Vineeta, primary, Rajasekhar, Liza, additional, Manuel, Sandra, additional, Nayana, V., additional, Kavadichanda, Chengappa, additional, Kounassegarane, Deepika, additional, Mathew, Ashish J., additional, Gupta, Ranjan, additional, Rathi, Manish, additional, Ghosh, Parasar, additional, Tripathy, Saumya Ranjan, additional, Das, Bidyut, additional, Selvam, Sumithra, additional, Singh, Abhishek Kumar, additional, Singh, Ankita, additional, Jain, Avinash, additional, and Aggarwal, Amita, additional
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- 2023
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82. Automated Classification of Sloan Digital Sky Survey (SDSS) Stellar Spectra using Artificial Neural Networks
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Bazarghan, Mahdi and Gupta, Ranjan
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Astrophysics - Abstract
Automated techniques have been developed to automate the process of classification of objects or their analysis. The large datasets provided by upcoming spectroscopic surveys with dedicated telescopes urges scientists to use these automated techniques for analysis of such large datasets which are now available to the community. Sloan Digital Sky Survey (SDSS) is one of such surveys releasing massive datasets. We use Probabilistic Neural Network (PNN) for automatic classification of about 5000 SDSS spectra into 158 spectral type of a reference library ranging from O type to M type stars., Comment: 27 pages, 11 figures To appear in Astrophys. Space Sci., 2008
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- 2008
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83. Bilateral peripheral ulcerative keratitis: A rare presentation of pediatric Behcet's disease
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Gaur, Sandhya, Kumari, Pooja, Lomi, Neiwete, Gupta, Ranjan, Vanathi, Murugesan, and Tandon, Radhika
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Children -- Diseases ,Behcet's disease -- Case studies -- Diagnosis ,Keratitis -- Case studies -- Diagnosis ,Health - Abstract
Byline: Sandhya. Gaur, Pooja. Kumari, Neiwete. Lomi, Ranjan. Gupta, Murugesan. Vanathi, Radhika. Tandon A 13-year-old girl presenting with mucopurulent conjunctivitis (left > right) was diagnosed with Behçet's disease. Intraoperatively, the [...]
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- 2023
84. A 3D Automated Classification Scheme for the TAUVEX data pipeline
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Bora, Archana, Gupta, Ranjan, Singh, Harinder P., Murthy, Jayant, Mohan, Rekhesh, and Duorah, Kalpana
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Astrophysics - Abstract
In order to develop a pipeline for automated classification of stars to be observed by the TAUVEX ultraviolet space Telescope, we employ an artificial neural network (ANN) technique for classifying stars by using synthetic spectra in the UV region from 1250\AA to 3220\AA as the training set and International Ultraviolet Explorer (IUE) low resolution spectra as the test set. Both the data sets have been pre-processed to mimic the observations of the TAUVEX ultraviolet imager. We have successfully classified 229 stars from the IUE low resolution catalog to within 3-4 spectral sub-class using two different simulated training spectra, the TAUVEX spectra of 286 spectral types and UVBLUE spectra of 277 spectral types. Further, we have also been able to obtain the colour excess (i.e. E(B-V) in magnitude units) or the interstellar reddening for those IUE spectra which have known reddening to an accuracy of better than 0.1 magnitudes. It has been shown that even with the limitation of data from just photometric bands, ANNs have not only classified the stars, but also provided satisfactory estimates for interstellar extinction. The ANN based classification scheme has been successfully tested on the simulated TAUVEX data pipeline. It is expected that the same technique can be employed for data validation in the ultraviolet from the virtual observatories. Finally, the interstellar extinction estimated by applying the ANNs on the TAUVEX data base would provide an extensive extinction map for our galaxy and which could in turn be modeled for the dust distribution in the galaxy., Comment: 8 pages, 12 figures, Accepted for publication in MNRAS; High resolution figures available from the authors on request
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- 2007
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85. A Near-Infrared Stellar Spectral Library: III. J-Band Spectra
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Ranade, Arvind C., Ashok, N. M., Singh, Harinder P., and Gupta, Ranjan
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Astrophysics - Abstract
This paper is the third in the series of papers published on near-infrared (NIR) stellar spectral library by Ranade et al. (2004 & 2007). The observations were carried out with 1.2 meter Gurushikhar Infrared Telescope (GIRT), at Mt. Abu, India using a NICMOS3 HgCdTe $256 \times 256$ NIR array based spectrometer. In paper I (Ranade et al. 2004), H-band spectra of 135 stars at a resolution of $\sim 16$\AA & paper II (Ranade et al. 2007), K band spectra of 114 stars at a resolution of $\sim 22$\AA were presented. The J-band library being released now consists of 126 stars covering spectral types O5--M8 and luminosity classes I--V. The spectra have a moderate resolution of $\sim 12.5$\AA in the J band and have been continuum shape corrected to their respective effective temperatures. The complete set of library in near-infrared (NIR) will serve as a good database for researchers working in the field of stellar population synthesis. The complete library in J, H & K is available online at: http://vo.iucaa.ernet.in/$\sim$voi/NIR\_Header.html, Comment: 10 figures. Accepted for Publication in Bulletin of Astronomical Society of India
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- 2007
86. A Near-Infrared Stellar Spectral Library: II. K-Band Spectra
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Ranade, Arvind C., Singh, Harinder P., Gupta, Ranjan, and Ashok, N. M.
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Astrophysics - Abstract
This paper is the second in the series of papers on near-infrared (NIR) stellar spectral library produced by reducing the observations carried out with 1.2 meter Gurushikhar Infrared Telescope (GIRT), at Mt. Abu, India using a NICMOS3 HgCdTe 256 X 256 NIR array based spectrometer. In paper I (Ranade et al. 2004), H-band spectra of 135 stars at a resolution of ~16 Ang were presented. The K-band library being released now consists of 114 stars covering spectral types O7--M7 and luminosity classes I--V. The spectra have a moderate resolution of ~22 Ang in the K band and have been continuum shape corrected to their respective effective temperatures. We hope to release the remaining J-band spectra soon. The complete H and K-Band library is available online at: http://vo.iucaa.ernet.in/~voi/NIR_Header.html, Comment: 26 pages, 10 figures. Accepted for Publication in Bulletin of Astronomical Society of India
- Published
- 2007
87. Composite Interstellar Grains
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Vaidya, D. B., Gupta, Ranjan, and Snow, T. P.
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Astrophysics - Abstract
The composite grain is made up of a host silicate spheroid and graphite inclusions. The extinction efficiencies of the composite spheroidal grains for three axial ratios are computed using the discrete dipole approximation (DDA). The interstellar extinction curve is evaluated in the spectral region 3.40--0.10$\mu m$ using the extinction efficiencies of the composite spheroidal grains. The model extinction curves are then compared with the average observed interstellar extinction curve. We also calculate the linear polarization for the spheroidal composite grains at three orientation angles and find the wavelength of maximum polarization. Further, we estimate the volume extinction factor, an important parameter from the point of view of cosmic abundance, for the composite grain models that reproduce the average observed interstellar extinction. The estimated abundances derived from the composite grain models for both carbon and silicon are found to be lower than that are predicted by the bare silicate/graphite grain models but these values are still higher than that are implied from the recent ISM values., Comment: 11 pages, 12 figures, 5 tables To appear in 2007 MNRAS
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- 2007
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88. Association of Dopamine pathway gene polymorphisms in patients with alcohol dependence
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Singh, Renu, Grover, Tripti, Ambekar, Atul, Gupta, Ranjan, Jain, Raka, Vaswani, Meera, Mishra, Ashwani, and Sharma, Arundhati
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- 2024
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89. Reliability checks on the Indo-US Stellar Spectral Library using Artificial Neural Networks and Principal Component Analysis
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Singh, Harinder P., Yuasa, Manabu, Yamamoto, Nawo, and Gupta, Ranjan
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Astrophysics - Abstract
The Indo-US coud\'{e} feed stellar spectral library (CFLIB) made available to the astronomical community recently by Valdes et al. (2004) contains spectra of 1273 stars in the spectral region 3460 to 9464 \AA at a high resolution of 1 \AA FWHM and a wide range of spectral types. Cross-checking the reliability of this database is an important and desirable exercise since a number of stars in this database have no known spectral types and a considerable fraction of stars has not so complete coverage in the full wavelength region of 3460-9464 \AA resulting in gaps ranging from a few \AA to several tens of \AA. In this paper, we use an automated classification scheme based on Artificial Neural Networks (ANN) to classify all 1273 stars in the database. In addition, principal component analysis (PCA) is carried out to reduce the dimensionality of the data set before the spectra are classified by the ANN. Most importantly, we have successfully demonstrated employment of a variation of the PCA technique to restore the missing data in a sample of 300 stars out of the CFLIB., Comment: 17 pages, 8 figures PASJ Vol.58, No1 (it will be issued on February 25, 2006)
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- 2005
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90. Interstellar Extinction by Spheroidal Dust Grains
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Gupta, Ranjan, Mukai, Tadashi, Vaidya, D. B., Sen, Asoke K., and Okada, Yasuhiko
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Astrophysics - Abstract
Observations of interstellar extinction and polarization indicate that the interstellar medium consists of aligned non-spherical dust grains which show variation in the interstellar extinction curve for wavelengths ranging from NIR to UV. To model the extinction and polarization, one cannot use the Mie theory which assumes the grains as solid spheres. We have used a T-matrix based method for computing the extinction efficiencies of spheroidal silicate and graphite grains of different shapes (axial ratios) and sizes and used these efficiencies to evaluate the interstellar extinction curve in the wavelength range 3.4--1.0 microns. A best fit linear combination of silicate and graphite grains of not very large axial ratio, fits the observed extinction curve reasonably well. We calculate the volume extinction factor Vc, which is an important parameter from the point of view of the cosmic abundance, for the spheroidal grain models that reproduce the interstellar extinction curve. We find that the shape of the grains do not affect the volume extinction factor. Finally we have also studied the extinction and linear polarization efficiencies for aligned spheroids. The results show that the shape of grains affects the linear polarization efficiencies considerably for various orientation angles of the spheroids., Comment: 10 pages, 6 figure To appear in A & A, 2005
- Published
- 2005
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91. Scattering properties and composition of cometary dust
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Gupta, Ranjan, Vaidya, D. B., Dobbie, J. S., and Chylek, P.
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Astrophysics - Abstract
Composition of Comet dust obtained by the dust impact analyser on the Halley probes indicated that the comet dust is a mixure of silicate and carbonaceous material. The collected interplanetary dust particles (IDP's) are fluffy and composite having grains of several different types stuck together. Using Discrete Dipole Approximation (DDA) we study the scattering properties of composite grains. In particular, we study the angular distribution of the scattered intensity and linear polarization of composite grains. We assume that the composite grains are made up of host silicate sphere/spheroid with the inclusions of graphite. Results of our calculations on the composite grains show that the angle of maximum polarization shifts, and the degree of polarizaion varies with the volume fraction of inclusions. We use these results on the composite grains to interpret the observed scattering in the cometary dust., Comment: 22 pages, 11 figures. To appear in Astrophysics & Space Science, 2005
- Published
- 2005
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92. Automated Classification of 2000 Bright IRAS Sources
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Gupta, Ranjan, Singh, Harinder P., Volk, K., and Kwok, S.
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Astrophysics - Abstract
An Artificial Neural Network (ANN) has been employed using a supervised back-propagation scheme to classify 2000 bright sources from the Calgary database of IRAS (Infrared Astronomy Satellite) spectra in the wavelength region of 8-23 microns. The data base has been classified into 17 pre-determined classes based on spectral morphology. We have been able to classify more than 80 percent of the 2000 sources correctly at the first instance. The speed and robustness of the scheme will allow us to classify the whole of LRS database, containing more than 50,000 sources in the future., Comment: 26 pages, To appear in ApJS after July 2004
- Published
- 2004
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93. The Indo-U.S. Library of Coude Feed Stellar Spectra
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Valdes, Francisco, Gupta, Ranjan, Rose, James A., Singh, Harinder P., and Bell, David J.
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Astrophysics - Abstract
We have obtained spectra for 1273 stars using the 0.9m Coud\'e Feed telescope at Kitt Peak National Observatory. This telescope feeds the coud\'e spectrograph of the 2.1m telescope. The spectra have been obtained with the #5 camera of the coud\'e spectrograph and a Loral 3K X 1K CCD. Two gratings have been used to provide spectral coverage from 3460 \AA to 9464 \AA, at a resolution of $\sim$1\AA FWHM and at an original dispersion of 0.44 \AA/pixel. For 885 stars we have complete spectra over the entire 3460 \AA to 9464 \AA wavelength region (neglecting small gaps of $<$ 50 \AA), and partial spectral coverage for the remaining stars. The 1273 stars have been selected to provide broad coverage of the atmospheric parameters T$_{eff}$, log g, and [Fe/H], as well as spectral type. The goal of the project is to provide a comprehensive library of stellar spectra for use in the automated classification of stellar and galaxy spectra and in galaxy population synthesis. In this paper we discuss the characteristics of the spectral library, viz., details of the observations, data reduction procedures, and selection of stars. We also present a few illustrations of the quality and information available in the spectra. The first version of the complete spectral library is now publicly available from the National Optical Astronomy Observatory (NOAO) via FTP and HTTP., Comment: 18 pages, 6 figures, 4 tables
- Published
- 2004
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94. In Vitro Studies on Ameliorative Effects of Limonene on Cadmium-Induced Genotoxicity in Cultured Human Peripheral Blood Lymphocytes
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Verma, Neha, Yadav, Anita, Bal, Surbhi, Gupta, Ranjan, and Aggarwal, Neeraj
- Published
- 2019
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95. Biophysical stimulation induces demyelination via an integrin‐dependent mechanism
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Lin, Michael Y, Frieboes, Laura S, Forootan, Maryam, Palispis, Winnie A, Mozaffar, Tahseen, Jafari, Matiar, Steward, Oswald, Gall, Christine M, and Gupta, Ranjan
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Biomedical and Clinical Sciences ,Neurosciences ,Clinical Sciences ,Physical Injury - Accidents and Adverse Effects ,Neurodegenerative ,Autoimmune Disease ,Neurological ,Animals ,Apoptosis ,Cell Proliferation ,Coculture Techniques ,Demyelinating Diseases ,Ganglia ,Spinal ,Integrins ,Neurons ,Rats ,Rats ,Sprague-Dawley ,Schwann Cells ,Sciatic Nerve ,Signal Transduction ,Neurology & Neurosurgery ,Clinical sciences - Abstract
ObjectiveChronic nerve compression (CNC) injuries occur when peripheral nerves are subjected to sustained mechanical forces, with increasing evidence implicating Schwann cells as key mediators. Integrins, a family of transmembrane adhesion molecules that are capable of intracellular signaling, have been implicated in a variety of biological processes such as myelination and nerve regeneration. In this study, we seek to define the physical stimuli mediating demyelination and to determine whether integrin plays a role in the demyelinating response.MethodsWe used a previously described in vitro model of CNC injury where myelinating neuron-Schwann cell cocultures were subjected to independent manipulations of hydrostatic pressure, hypoxia, and glucose deprivation in a custom bioreactor. We assessed whether demyelination increased in response to applied manipulation and determined whether integrin-associated signaling cascades are upregulated.ResultsBiophysical stimulation of neural tissue induced demyelination and Schwann cell proliferation without neuronal or glial cytotoxicity or apoptosis. Although glucose deprivation and hypoxia independently had minor effects on myelin stability, together they potentiated the demyelinating effects of hydrostatic compression, and in combination, significantly destabilized myelin. Biophysical stimuli transiently increased phosphorylation of the integrin-associated tyrosine kinase Src within Schwann cells. Silencing this integrin signaling cascade blocked Src activation and prevented pressure-induced demyelination. Colocalization analysis indicated that Src is localized within Schwann cells.InterpretationThese results indicate that myelin is sensitive to CNC injury and support the novel concept that myelinating cocultures respond directly to mechanical loading via activating an integrin signaling cascade.
- Published
- 2012
96. Drivers of surgery for the degenerative hip, knee, and spine: a systematic review.
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Bederman, S Samuel, Rosen, Charles D, Bhatia, Nitin N, Kiester, P Douglas, and Gupta, Ranjan
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Aged ,Arthroplasty ,Replacement: economics ,Female ,Health Services Needs and Demand ,Hip Joint: surgery ,Humans ,Insurance ,Health ,Knee Joint: surgery ,Male ,Middle Aged ,Sex Factors ,Spine: surgery - Abstract
Surgical treatment for degenerative conditions of the hip, knee, and spine has an impact on overall healthcare spending. Surgical rates have increased dramatically and considerable regional variation has been observed. The reasons behind these increasing rates and variation across regions have not been well elucidated.We therefore identified demographic (D), social structure (SS), health belief (HB), personal (PR) and community resources (CR), and medical need (MN) factors that drive rates of hip, knee, and spine surgery.We conducted a systematic review to include all observational, population-based studies that compared surgical rates with potential drivers (D, SS, HB, PR, CR, MN). We searched PubMed combining key words focusing on (1) disease and procedure; (2) study methodology; and (3) explanatory models. Independent investigators selected potentially eligible studies from abstract review and abstracted methodological and outcome data. From an initial search of 256 articles, we found 37 to be potentially eligible (kappa 0.86) but only 28 met all our inclusion criteria.Age, nonminority, insurance coverage, and surgeon enthusiasm all increased surgical rates. Rates of arthroplasty were higher for females with higher education, income, obesity, rurality, willingness to consider surgery, and prevalence of disease, whereas spinal rates increased with male gender, lower income, and the availability of advanced imaging.Regional variation in these procedures exists because they are examples of preference-sensitive care. With strategies that may affect change in factors that are potentially modifiable by behavior or resources, extreme variation in rates may be reduced.
- Published
- 2012
97. Signal to Noise Ratio Based Wi-Fi Offloading Decision Algorithm in Vehicular Networks
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Kumar, Krishan and Gupta, Ranjan Kumar
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- 2018
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98. Clinical Case Vignettes: Connective Tissue Diseases in Children
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Gupta, Ranjan, Aggarwal, Amita, Sawhney, Sujata, editor, and Aggarwal, Amita, editor
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- 2017
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99. Human Motor Endplate Survival after Chronic Peripheral Nerve Injury
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Gupta, Ranjan, primary, Johnston, Tyler R, additional, Chen, Vivian Y, additional, Gonzales, Luigi P, additional, and Steward, Oswald, additional
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- 2023
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100. Understanding the mechanisms of entrapment neuropathies
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Pham, Khoa and Gupta, Ranjan
- Subjects
carpal tunnel syndrome ,chronic nerve compression ,nerve entrapment ,Schwann cellchronic nerve compression ,myelin-associated glycoprotein ,carpal-tunnel-syndrome ,wallerian degeneration ,schwann-cells ,acetylcholine-receptors ,macrophage recruitment ,lanterman incisures ,neurite outgrowth ,peripheral-nerve - Abstract
Compression neuropathies are highly prevalent, debilitating conditions with variable functional recovery following surgical decompression. Due to the limited amount of human nerve tissue available for analysis, a number of animal models have been created to help investigators understand the molecular and cellular pathogenesis of chronic nerve compression (CNC) injury. Evidence suggests that CNC injury induces concurrent Schwann cell proliferation and apoptosis in the early stages of the disorder. These proliferating Schwann cells downregulate myelin proteins, leading to local demyelination and remyelination in the region of injury. In addition, the downregulation of myelin proteins, in particular myelin-associated glycoprotein, allows for axonal sprouting. Interestingly, these changes occur in the absence of both morphological and electrophysiological evidence of axonal damage. This is in direct contrast to acute injuries, such as transection or crush, which are characterized by axonal injury followed by Wallerian degeneration. Because the accepted trigger for Schwann cell dedifferentiation is axonal injury, an alternate mechanism for Schwann response must exist in CNC injury. In vitro studies of pure Schwann cells have shown that these cells can respond directly to mechanical stimuli by downregulating myelin proteins and proliferating. These studies suggest that although the reciprocal relationship between neurons and glial cells is maintained, chronic nerve compression injury is a Schwann cell-mediated disease. (DOI: 10.3171/FOC.2009.26.2.E7)
- Published
- 2009
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