37,744 results on '"Guillot A"'
Search Results
52. Synthesis of lithium conducting titanium phosphates by the sol-gel process
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Guillot, A., Giaume, D., Suvorova, A., Rager, M. N., de Lacaillerie, J.-B. d’Espinose, Mir, C., Randrema, X., and Barboux, P.
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- 2024
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53. Protracted magmatism and crust–mantle interaction during continental collision: insights from the Variscan granitoids of the external western Alps
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Fréville, Kévin, Jacob, Jean-Baptiste, Vanardois, Jonas, Trap, Pierre, Melleton, Jérémie, Faure, Michel, Guillot, Stéphane, Janots, Emilie, Bruguier, Olivier, Poujol, Marc, Lach, Philippe, and Révillon, Sidonie
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- 2024
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54. Update on the management of older patients with pancreatic adenocarcinoma: a perspective from medical oncology
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Guillot Morales, Mónica, Visa, Laura, Brozos Vázquez, Elena, Feliu Batlle, Jaime, Khosravi Shahi, Parham, Laquente Sáez, Berta, de San Vicente Hernández, Borja López, Macarulla, Teresa, and Gironés Sarrió, Regina
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- 2024
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55. Acquisition of epithelial plasticity in human chronic liver disease
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Gribben, Christopher, Galanakis, Vasileios, Calderwood, Alexander, Williams, Eleanor C., Chazarra-Gil, Ruben, Larraz, Miguel, Frau, Carla, Puengel, Tobias, Guillot, Adrien, Rouhani, Foad J., Mahbubani, Krishnaa, Godfrey, Edmund, Davies, Susan E., Athanasiadis, Emmanouil, Saeb-Parsy, Kourosh, Tacke, Frank, Allison, Michael, Mohorianu, Irina, and Vallier, Ludovic
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- 2024
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56. Contribution of Potentially Inappropriate Medications to Polypharmacy-Associated Risk of Mortality in Middle-Aged Patients: A National Cohort Study
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Guillot, Jordan, Justice, Amy C., Gordon, Kirsha S., Skanderson, Melissa, Pariente, Antoine, Bezin, Julien, and Rentsch, Christopher T.
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- 2024
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57. Moderators of Loneliness Trajectories in People with Systemic Sclerosis During the COVID-19 Pandemic: A SPIN COVID-19 Cohort Longitudinal Study
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Rapoport, Chelsea S., Choi, Alyssa K., Kwakkenbos, Linda, Carrier, Marie-Eve, Henry, Richard S., Levis, Brooke, Bartlett, Susan J., Gietzen, Amy, Gottesman, Karen, Guillot, Geneviève, Lawrie-Jones, Amanda, Mayes, Maureen D., Mouthon, Luc, Richard, Michelle, Worron-Sauvé, Maureen, Benedetti, Andrea, Roesch, Scott C., Thombs, Brett D., and Malcarne, Vanessa L.
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- 2024
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58. On the hypothesis of an inverted Z-gradient inside Jupiter
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Howard, Saburo, Guillot, Tristan, Markham, Steve, Helled, Ravit, Müller, Simon, Stevenson, David J., Lunine, Jonathan I., Miguel, Yamila, and Nettelmann, Nadine
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Models of Jupiter s interior struggle to agree with measurements of the atmospheric composition. Interior models favour a subsolar or solar abundance of heavy elements Z while atmospheric measurements suggest a supersolar abundance. One potential solution may be the presence of an inverted Z-gradient, namely an inward decrease of Z, which implies a larger heavy element abundance in the atmosphere than in the outer envelope. We investigate two scenarios in which the inverted Z gradient is located either where helium rain occurs (Mbar level) or at upper levels (kbar level) where a radiative region could exist. We aim to assess how plausible these scenarios are. We calculate interior and evolution models of Jupiter with such inverted Z-gradient and use constraints on the stability and the formation of an inverted Z-gradient. We find that an inverted Z-gradient at the location of helium rain cannot work as it requires a late accretion and of too much material. We find interior models with an inverted Z-gradient at upper levels, due to a radiative zone preventing downward mixing, that could satisfy the present gravity field of the planet. However, our evolution models suggest that this second scenario might not be in place. An inverted Z-gradient in Jupiter could be stable. Yet, its presence either at the Mbar level or kbar level is rather unlikely., Comment: Accepted for publication in A&A
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- 2023
59. Negativity-preserving transforms of tuples of symmetric matrices
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Belton, Alexander, Guillot, Dominique, Khare, Apoorva, and Putinar, Mihai
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Mathematics - Classical Analysis and ODEs ,Mathematics - Functional Analysis ,15B48 (primary), 15A18, 26A48, 32A05 (secondary) - Abstract
Compared to the entrywise transforms which preserve positive semidefiniteness, those leaving invariant the inertia of symmetric matrices reveal a surprising rigidity. We first obtain the classification of negativity preservers by combining recent advances in matrix analysis with some novel arguments using well chosen test matrices. We continue with the analogous classification in the multi-variable setting, revealing a striking separation of variables, with absolute monotonicity on one side and homotheties on the other. We conclude with the complex analogue of this result., Comment: 42 pages, no figures, LaTeX. (1) Results significantly strengthened, by removing all restrictions on the target negative inertia "l". Significant edits to the exposition (except Section 3 and Appendix A). (2) The previous "Theorems B and C" are merged into a unified Theorem B. (3) A new Theorem C and Section 6 are added, working out the analoguous results for complex Hermitian matrices
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- 2023
60. Matrix positivity preservers in fixed dimension. II: positive definiteness and strict monotonicity of Schur function ratios
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Belton, Alexander, Guillot, Dominique, Khare, Apoorva, and Putinar, Mihai
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Mathematics - Classical Analysis and ODEs ,Mathematics - Combinatorics ,Mathematics - Functional Analysis ,15B48 (primary), 05E05, 15A24, 15A45, 26C05 (secondary) - Abstract
We continue the study of real polynomials acting entrywise on matrices of fixed dimension to preserve positive semidefiniteness, together with the related analysis of order properties of Schur polynomials. Previous work has shown that, given a real polynomial with positive coefficients that is perturbed by adding a higher-degree monomial, there exists a negative lower bound for the coefficient of the perturbation which characterizes when the perturbed polynomial remains positivity preserving. We show here that, if the perturbation coefficient is strictly greater than this bound then the transformed matrix becomes positive definite given a simple genericity condition that can be readily verified. We identity a slightly stronger genericity condition that ensures positive definiteness occurs at the boundary. The analysis is complemented by computing the rank of the transformed matrix in terms of the location of the original matrix in a Schubert cell-type stratification that we have introduced and explored previously. The proofs require enhancing to strictness a Schur monotonicity result of Khare and Tao, to show that the ratio of Schur polynomials is strictly increasing along each coordinate on the positive orthant and non-decreasing on its closure whenever the defining tuples satisfy a coordinate-wise domination condition., Comment: 26 pages, no figures, LaTeX
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- 2023
61. Ejecta Evolution Following a Planned Impact into an Asteroid: The First Five Weeks
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Kareta, Theodore, Thomas, Cristina, Li, Jian-Yang, Knight, Matthew M., Moskovitz, Nicholas, Rozek, Agata, Bannister, Michele T., Ieva, Simone, Snodgrass, Colin, Pravec, Petr, Ryan, Eileen V., Ryan, William H., Fahnestock, Eugene G., Rivkin, Andrew S., Chabot, Nancy, Fitzsimmons, Alan, Osip, David, Lister, Tim, Sarid, Gal, Hirabayashi, Masatoshi, Farnham, Tony, Tancredi, Gonzalo, Michel, Patrick, Wainscoat, Richard, Weryk, Rob, Burrati, Bonnie, Pittichova, Jana, Ridden-Harper, Ryan, Tan, Nicole J., Tristram, Paul, Brown, Tyler, Bonavita, Mariangela, Burgdorf, Martin, Khalouei, Elahe, Longa, Penelope, Rabus, Markus, Sajadian, Sedighe, Jorgensen, Uffe Graae, Dominik, Martin, Kikwaya, Jean-Baptiste, Epifani, Elena Mazzotta, Dotto, Elisabetta, Deshapriya, J. D. Prasanna, Hasselmann, Pedro H., Dall'Ora, Massimo, Abe, Lyu, Guillot, Tristan, Mekarnia, Djamel, Agabi, Abdelkrim, Bendjoya, Philippe, Suarez, Olga, Triaud, Amaury, Gasparetto, Thomas, Gunther, Maximillian N., Kueppers, Michael, Merin, Bruno, Chatelain, Joseph, Gomez, Edward, Usher, Helen, Stoddard-Jones, Cai, Bartnik, Matthew, Bellaver, Michael, Chetan, Brenna, Dugan, Emma, Fallon, Tori, Fedewa, Jeremy, Gerhard, Caitlyn, Jacobson, Seth A., Painter, Shane, Peterson, David-Michael, Rodriguez, Joseph E., Smith, Cody, Sokolovsky, Kirill V., Sullivan, Hannah, Townley, Kate, Watson, Sarah, Webb, Levi, Trigo-Rodrıguez, Josep M., Llenas, Josep M., Perez-Garcıa, Ignacio, Castro-Tirado, A. J., Vincent, Jean-Baptiste, Migliorini, Alessandra, Lazzarin, Monica, La Forgia, Fiorangela, Ferrari, Fabio, Polakis, Tom, and Skiff, Brian
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The impact of the DART spacecraft into Dimorphos, moon of the asteroid Didymos, changed Dimorphos' orbit substantially, largely from the ejection of material. We present results from twelve Earth-based facilities involved in a world-wide campaign to monitor the brightness and morphology of the ejecta in the first 35 days after impact. After an initial brightening of ~1.4 magnitudes, we find consistent dimming rates of 0.11-0.12 magnitudes/day in the first week, and 0.08-0.09 magnitudes/day over the entire study period. The system returned to its pre-impact brightness 24.3-25.3 days after impact through the primary ejecta tail remained. The dimming paused briefly eight days after impact, near in time to the appearance of the second tail. This was likely due to a secondary release of material after re-impact of a boulder released in the initial impact, through movement of the primary ejecta through the aperture likely played a role., Comment: 16 pages, 5 Figures, accepted in the Astrophysical Journal Letters (ApJL) on October 16, 2023
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- 2023
62. X-ray and Radio Monitoring of the Neutron Star Low Mass X-ray Binary 1A 1744-361: Quasi Periodic Oscillations, Transient Ejections, and a Disk Atmosphere
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Ng, Mason, Hughes, Andrew K., Homan, Jeroen, Miller, Jon M., Pike, Sean N., Altamirano, Diego, Bult, Peter, Chakrabarty, Deepto, Buisson, D. J. K., Coughenour, Benjamin M., Fender, Rob, Guillot, Sebastien, Güver, Tolga, Jaisawal, Gaurava K., Jaodand, Amruta D., Malacaria, Christian, Miller-Jones, James C. A., Sanna, Andrea, Sivakoff, Gregory R., Strohmayer, Tod E., Tomsick, John A., and Eijnden, Jakob van den
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report on X-ray (NICER/NuSTAR/MAXI/Swift) and radio (MeerKAT) timing and spectroscopic analysis from a three-month monitoring campaign in 2022 of a high-intensity outburst of the dipping neutron star low-mass X-ray binary 1A 1744-361. The 0.5-6.8 keV NICER X-ray hardness-intensity and color-color diagrams of the observations throughout the outburst suggests that 1A 1744-361 spent most of its outburst in an atoll-state, but we show that the source exhibited Z-state-like properties at the peak of the outburst, similar to a small sample of other atoll-state sources. A timing analysis with NICER data revealed several instances of an $\approx8$ Hz quasi-periodic oscillation (QPO; fractional rms amplitudes of ~5%) around the peak of the outburst, the first from this source, which we connect to the normal branch QPOs (NBOs) seen in the Z-state. Our observations of 1A 1744-361 are fully consistent with the idea of the mass accretion rate being the main distinguishing parameter between atoll- and Z-states. Radio monitoring data by MeerKAT suggests that the source was at its radio-brightest during the outburst peak, and that the source transitioned from the 'island' spectral state to the 'banana' state within ~3 days of the outburst onset, launching transient jet ejecta. The observations present the strongest evidence for radio flaring, including jet ejecta, during the island-to-banana spectral state transition at low accretion rates (atoll-state). The source also exhibited Fe XXV, Fe XXVI K$\alpha$, and K$\beta$ X-ray absorption lines, whose origins likely lie in an accretion disk atmosphere., Comment: 30 pages, 13 figures, and 8 tables. Accepted by ApJ (before proofs)
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- 2023
63. TOI-199 b: A well-characterized 100-day transiting warm giant planet with TTVs seen from Antarctica
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Hobson, Melissa J., Trifonov, Trifon, Henning, Thomas, Jordán, Andrés, Rojas, Felipe, Espinoza, Nestor, Brahm, Rafael, Eberhardt, Jan, Jones, Matías I., Mekarnia, Djamel, Kossakowski, Diana, Schlecker, Martin, Pinto, Marcelo Tala, Miranda, Pascal José Torres, Abe, Lyu, Barkaoui, Khalid, Bendjoya, Philippe, Bouchy, François, Buttu, Marco, Carleo, Ilaria, Collins, Karen A., Colón, Knicole D., Crouzet, Nicolas, Dragomir, Diana, Dransfield, Georgina, Gasparetto, Thomas, Goeke, Robert F., Guillot, Tristan, Günther, Maximilian N., Howard, Saburo, Jenkins, Jon M., Korth, Judith, Latham, David W., Lendl, Monika, Lissauer, Jack J., Mann, Christopher R., Mireles, Ismael, Ricker, George R., Saesen, Sophie, Schwarz, Richard P., Seager, S., Sefako, Ramotholo, Shporer, Avi, Stockdale, Chris, Suarez, Olga, Tan, Thiam-Guan, Triaud, Amaury H. M. J., Ulmer-Moll, Solène, Vanderspek, Roland, Winn, Joshua N., Wohler, Bill, and Zhou, George
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We present the spectroscopic confirmation and precise mass measurement of the warm giant planet TOI-199 b. This planet was first identified in TESS photometry and confirmed using ground-based photometry from ASTEP in Antarctica including a full 6.5$\,$h long transit, PEST, Hazelwood, and LCO; space photometry from NEOSSat; and radial velocities (RVs) from FEROS, HARPS, CORALIE, and CHIRON. Orbiting a late G-type star, TOI-199\,b has a $\mathrm{104.854_{-0.002}^{+0.001} \, d}$ period, a mass of $\mathrm{0.17\pm0.02 \, M_J}$, and a radius of $\mathrm{0.810\pm0.005 \, R_J}$. It is the first warm exo-Saturn with a precisely determined mass and radius. The TESS and ASTEP transits show strong transit timing variations, pointing to the existence of a second planet in the system. The joint analysis of the RVs and TTVs provides a unique solution for the non-transiting companion TOI-199 c, which has a period of $\mathrm{273.69_{-0.22}^{+0.26} \, d}$ and an estimated mass of $\mathrm{0.28_{-0.01}^{+0.02} \, M_J}$. This period places it within the conservative Habitable Zone., Comment: 33 pages, 23 figures. Accepted for publication in AJ
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- 2023
64. Small body harvest with the Antarctic Search for Transiting Exoplanets (ASTEP) project
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Hasler, Samantha, Burdanov, Artem, de Wit, Julien, Dransfield, Georgina, Abe, Lyu, Agabi, A., Bendjoya, Philippe, Crouzet, Nicolas, Guillot, Tristan, Mékarnia, Djamel, Schmider, F. -X., Suárez, Olga, and Triaud, Amaury
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Small Solar system bodies serve as pristine records that have been minimally altered since their formation. Their observations provide valuable information regarding the formation and evolution of our Solar system. Interstellar objects (ISOs) can also provide insight on the formation of exoplanetary systems and planetary system evolution as a whole. In this work, we present the application of our framework to search for small Solar system bodies in exoplanet transit survey data collected by the Antarctic Search for Transiting ExoPlanets (ASTEP) project. We analysed data collected during the Austral winter of 2021 by the ASTEP 400 telescope located at the Concordia Station, at Dome C, Antarctica. We identified 20 known objects from dynamical classes ranging from Inner Main-belt asteroids to one comet. Our search recovered known objects down to a magnitude of $V$ = 20.4 mag, with a retrieval rate of $\sim$80% for objects with $V \le $ 20 mag. Future work will apply the pipeline to archival ASTEP data that observed fields for periods of longer than a few hours to treat them as deep-drilling datasets and reach fainter limiting magnitudes for slow-moving objects, on the order of $V\approx $ 23-24 mag., Comment: Accepted for publication in MNRAS (Monthly Notices of the Royal Astronomical Society), 9 pages, 8 figures
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- 2023
65. NICER observations of thermonuclear bursts from 4U 1728-34: Detection of oscillations prior to the onset of two bursts
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Bostanci, Funda, Boztepe, Tugba, Guver, Tolga, Strohmayer, Tod E., Cavecchi, Yuri, Gogus, Ersin, Altamirano, Diego, Bult, Peter, Chakrabarty, Deepto, Guillot, Sebastien, Jaisawal, Gaurava K., Malacaria, Christian, Mancuso, Giulio C., Sanna, Andrea, and Swank, Jean H.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present temporal and time-resolved spectral analyses of all the thermonuclear X-ray bursts observed from the neutron star low-mass X-ray binary (LMXB) 4U 1728-34 with NICER from June 2017 to September 2019. In total, we detected 11 X-ray bursts from the source and performed time-resolved spectroscopy. Unlike some of the earlier results for other bursting sources from NICER, our spectral results indicate that the use of a scaling factor for the persistent emission is not statistically necessary. This is primarily a result of the strong interstellar absorption in the line of sight towards 4U 1728-34, which causes the count rates to be significantly lower at low energies. We also searched for burst oscillations and detected modulations in six different bursts at around the previously known burst oscillation frequency of 363 Hz. Finally, we report the detection of oscillations prior to two bursts at 356 and 359 Hz, respectively. This is the first time in the literature where burst oscillations are detected before the rapid rise in X-ray flux, from any known burster. These oscillations disappear as soon as the burst rise starts and occur at a somewhat lower frequency than the oscillations we detect during the bursts., Comment: Accepted for publication in the Astrophysical Journal
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- 2023
66. MMST-ViT: Climate Change-aware Crop Yield Prediction via Multi-Modal Spatial-Temporal Vision Transformer
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Lin, Fudong, Crawford, Summer, Guillot, Kaleb, Zhang, Yihe, Chen, Yan, Yuan, Xu, Chen, Li, Williams, Shelby, Minvielle, Robert, Xiao, Xiangming, Gholson, Drew, Ashwell, Nicolas, Setiyono, Tri, Tubana, Brenda, Peng, Lu, Bayoumi, Magdy, and Tzeng, Nian-Feng
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Precise crop yield prediction provides valuable information for agricultural planning and decision-making processes. However, timely predicting crop yields remains challenging as crop growth is sensitive to growing season weather variation and climate change. In this work, we develop a deep learning-based solution, namely Multi-Modal Spatial-Temporal Vision Transformer (MMST-ViT), for predicting crop yields at the county level across the United States, by considering the effects of short-term meteorological variations during the growing season and the long-term climate change on crops. Specifically, our MMST-ViT consists of a Multi-Modal Transformer, a Spatial Transformer, and a Temporal Transformer. The Multi-Modal Transformer leverages both visual remote sensing data and short-term meteorological data for modeling the effect of growing season weather variations on crop growth. The Spatial Transformer learns the high-resolution spatial dependency among counties for accurate agricultural tracking. The Temporal Transformer captures the long-range temporal dependency for learning the impact of long-term climate change on crops. Meanwhile, we also devise a novel multi-modal contrastive learning technique to pre-train our model without extensive human supervision. Hence, our MMST-ViT captures the impacts of both short-term weather variations and long-term climate change on crops by leveraging both satellite images and meteorological data. We have conducted extensive experiments on over 200 counties in the United States, with the experimental results exhibiting that our MMST-ViT outperforms its counterparts under three performance metrics of interest.
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- 2023
67. Constraining the magnetic field geometry of the millisecond pulsar PSR~J0030+0451 from joint radio, thermal X-ray and $\gamma$-ray emission
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Pétri, J., Guillot, S., Guillemot, L., Cognard, I., Theureau, G., Grießmeier, J. -M., Bondonneau, L., González-Caniulef, D., Webb, N., Jankowski, F., Kravtsov, I. P., McKee, J. W., Carozzi, T. D., Cecconi, B., Serylak, M., and Zarka, P.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
With the advent of multi-wavelength electromagnetic observations of neutron stars, spanning many decades in photon energies, from radio wavelengths up to X-rays and $\gamma$-rays, it becomes possible to significantly constrain the geometry and the location of the associated emission regions. In this work, we use results from the modelling of thermal X-ray observations of PSR~J0030+0451 from the NICER mission and phase-aligned radio and $\gamma$-ray pulse profiles to constrain the geometry of an off-centred dipole able to reproduce the light-curves in these respective bands simultaneously. To this aim, we deduce a configuration with a simple dipole off-centred from the location of the centre of the thermal X-ray hot spots and show that the geometry is compatible with independent constraints from radio and $\gamma$-ray pulsations only, leading to a fixed magnetic obliquity of $\alpha \approx 75\deg$ and a line of sight inclination angle of $\zeta \approx 54\deg$. We demonstrate that an off-centred dipole cannot be rejected by accounting for the thermal X-ray pulse profiles. Moreover, the crescent shape of one spot is interpreted as the consequence of a small scale surface dipole on top of the large scale off-centred dipole., Comment: Accepted for publication in A&A
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- 2023
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68. Golf Strategy Optimization and the Value of Golf Skills
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Stauffer, Gautier and Guillot, Matthieu
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Mathematics - Optimization and Control - Abstract
This study investigates strategic considerations in professional golf's Stroke Play format. We develop a Markov Decision Process (MDP) model, specifically a stochastic shortest path model, to optimize a golfer's strategy for any golf course. The model integrates golf course layout details and player skills. We demonstrate this approach using Professional Golfers' Association Tour data and aerial views of golf courses. To the best of our knowledge, this is the first exact, data-driven approach for golf strategy optimization in the literature. While MDPs are commonly used for sport strategy optimization, scaling this approach to golf poses a challenge due to the curse of dimensionality. Our primary objective is to prove that an exact approach is computationally feasible for such large-scale problems, provided that low-level coding and meticulous code optimization are employed. Furthermore, we illustrate how this framework could be used to determine which aspects of a player's game should be prioritized for improvement and challenge the "Drive for show, putt for dough adage". Additionally, we demonstrate how our methodology can be used to quantify the value of different golf skills.To ensure replicability and facilitate the adaptation and extension of our methodology, we provide open access to all our codes and analyses (in R and C++).
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- 2023
69. Seasonal and climatic influence on respiratory infections in children with cystic fibrosis
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Julie Mésinèle, Manon Ruffin, Loïc Guillot, Pierre-Yves Boëlle, Harriet Corvol, and French CF Modifier Gene Study Investigators
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Environmental factors ,Seasonality ,Climate ,Cystic fibrosis ,Pseudomonas aeruginosa ,Staphylococcus aureus ,Medicine ,Science - Abstract
Abstract Pseudomonas aeruginosa (Pa) and Methicillin susceptible Staphylococcus aureus (MSSA) are the predominant bacteria found in the airways of people with cystic fibrosis (pwCF), significantly contributing to lung disease progression. While various factors influencing the initial acquisition (IA) of these pathogens are known, the impact of environmental conditions remains understudied. This epidemiological study assessed the risk of MSSA and Pa initial acquisitions in relation to seasonality and climatic zones among 1,184 French pwCF under 18 years old. The age at IA for Pa (Pa-IA) and MSSA (MSSA-IA) was estimated using the Kaplan–Meier method. Seasonality and climatic zones were analysed as risk factors using time-varying Cox regression models. The median age at MSSA-IA was notably earlier (2.0 years) than that at Pa-IA (5.1 years). MSSA-IA occurred increasingly younger in more recent birth cohorts, while the age at Pa-IA remained stable over time. The risk of Pa-IA was consistently higher in all seasons compared with spring, peaking in autumn (HR = 1.53), irrespective of climatic zones. In Oceanic and Continental climates, the highest risk for MSSA-IA was in winter (HRs = 1.45 and 1.20 respectively). In the Mediterranean climate, the risk of MSSA-IA was lower in winter compared to spring (HRs = 0.68 and 0.61 respectively), and the median age at MSSA-IA later than for Pa-IA. This study demonstrates that seasonality and meteorological factors may influence acquisition of MSSA and Pa in pwCF. These findings suggest that environmental factors play a role in pathogen acquisition dynamics in CF and could inform the development of preventive strategies.
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- 2024
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70. Leveraging weak complementary labels enhances semantic segmentation of hepatocellular carcinoma and intrahepatic cholangiocarcinoma
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Miriam Hägele, Johannes Eschrich, Lukas Ruff, Maximilian Alber, Simon Schallenberg, Adrien Guillot, Christoph Roderburg, Frank Tacke, and Frederick Klauschen
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Medicine ,Science - Abstract
Abstract In this paper we present a deep learning segmentation approach to classify and quantify the two most prevalent primary liver cancers – hepatocellular carcinoma and intrahepatic cholangiocarcinoma – from hematoxylin and eosin (H&E) stained whole slide images. While semantic segmentation of medical images typically requires costly pixel-level annotations by domain experts, there often exists additional information which is routinely obtained in clinical diagnostics but rarely utilized for model training. We propose to leverage such weak information from patient diagnoses by deriving complementary labels that indicate to which class a sample cannot belong to. To integrate these labels, we formulate a complementary loss for segmentation. Motivated by the medical application, we demonstrate for general segmentation tasks that including additional patches with solely weak complementary labels during model training can significantly improve the predictive performance and robustness of a model. On the task of diagnostic differentiation between hepatocellular carcinoma and intrahepatic cholangiocarcinoma, we achieve a balanced accuracy of 0.91 (CI 95%: 0.86-0.95) at case level for 165 hold-out patients. Furthermore, we also show that leveraging complementary labels improves the robustness of segmentation and increases performance at case level.
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- 2024
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71. Association of Aggression with Lower Urinary Tract Symptoms and Overactive Bladder in Men: Observations from a Large Population-representative Study
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Mikolaj Przydacz, Pawel Rajwa, Sabrina De Cillis, Cyrille Guillot-Tantay, Francois Herve, Antonio Tienza, Manuela Tutolo, Mehmet Gokhan Culha, Paolo Geretto, Nicholas Raison, Glenn T. Werneburg, Marcin Miszczyk, Juan Gomez Rivas, Veronique Phe, Piotr Chlosta, and Nadir Osman
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Aggression ,Lower urinary tract symptoms ,Overactive bladder ,Diseases of the genitourinary system. Urology ,RC870-923 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background and objective: Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) intimately affect the psychological wellbeing and mental health of men. However, to date, the association of aggression with LUTS and OAB has not been investigated. To address this knowledge gap, we evaluated the association of aggression with LUTS and OAB in a large representative cohort of men at the population level. Methods: We used computer-assisted web interviews that included reliable questionnaires for assessment of LUTS, OAB, and aggression. A population-representative group of men was based on the most recent census. For data analysis, we developed univariate and multivariate regression models. Key findings and limitations: We analyzed data for a cohort of 3001 men that was representative for age and place of residence. Aggression was more prevalent among respondents with LUTS and OAB in comparison to men without these conditions (p
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- 2024
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72. XPS Investigation of Co–Ni Oxidized Compounds Surface Using Peak-On-Satellite Ratio. Application to Co20Ni80 Passive Layer Structure and Composition
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Barbara Laïk, Morgane Richet, Nicolas Emery, Stephane Bach, Loïc Perrière, Yvan Cotrebil, Vincent Russier, Ivan Guillot, and Pierre Dubot
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Chemistry ,QD1-999 - Published
- 2024
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73. Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity
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Jonathan P. Mochel, Jessica L. Ward, Thomas Blondel, Debosmita Kundu, Maria M. Merodio, Claudine Zemirline, Emilie Guillot, Ryland T. Giebelhaus, Paulina de la Mata, Chelsea A. Iennarella-Servantez, April Blong, Seo Lin Nam, James J. Harynuk, Jan Suchodolski, Asta Tvarijonaviciute, José Joaquín Cerón, Agnes Bourgois-Mochel, Faiez Zannad, Naveed Sattar, and Karin Allenspach
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Western diet ,Metabolic syndrome ,Cardiorenal metabolic diseases ,One health ,Medicine ,Science - Abstract
Abstract Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk factors, chronic kidney disease, and the cardiovascular system. A growing body of literature suggests that metabolic syndrome (MetS) in individuals of normal weight is associated with a high prevalence of cardiovascular diseases and an increased mortality. The aim of this study was to establish a non-invasive preclinical model of MetS in support of future research focusing on the effects of novel antidiabetic therapies beyond glucose reduction, independent of obesity. Eighteen healthy adult Beagle dogs were fed an isocaloric Western diet (WD) for ten weeks. Biospecimens were collected at baseline (BAS1) and after ten weeks of WD feeding (BAS2) for measurement of blood pressure (BP), serum chemistry, lipoprotein profiling, blood glucose, glucagon, insulin secretion, NT-proBNP, angiotensins, oxidative stress biomarkers, serum, urine, and fecal metabolomics. Differences between BAS1 and BAS2 were analyzed using non-parametric Wilcoxon signed-rank testing. The isocaloric WD model induced significant variations in several markers of MetS, including elevated BP, increased glucose concentrations, and reduced HDL-cholesterol. It also caused an increase in circulating NT-proBNP levels, a decrease in serum bicarbonate, and significant changes in general metabolism, lipids, and biogenic amines. Short-term, isocaloric feeding with a WD in dogs replicated key biological features of MetS while also causing low-grade metabolic acidosis and elevating natriuretic peptides. These findings support the use of the WD canine model for studying the metabolic effects of new antidiabetic therapies independent of obesity.
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- 2024
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74. Drinking among College Student Athletes during the COVID-19 Pandemic
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Casey R. Guillot, E. Whitney G. Moore, and Trent A. Petrie
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Objective: To investigate demographics, sport type, athletic identity, and COVID-19 sport season cancelation in relation to alcohol consumption among college student athletes shortly after the pandemic emerged. Participants: College student athletes recruited from U.S. athletic departments. Methods: Survey data were collected from 5,915 college student athletes in April/May 2020. Results: Being female, Latinx, and in a relationship were associated with lower alcohol consumption. Among males, team sport participation was related to greater alcohol consumption. Among females, athletic identity was inversely related to drinking, which was moderated by sport type, such that alcohol consumption was lower as athletic identity strengthened in individual (vs. team) sport athletes. However, we did not find a relationship of COVID-19 sport season cancelation with drinking. Conclusions: Our gender-specific findings are novel and generalizable based on a large, national sample of college student athletes, and may inform strategies for alcohol consumption education among college team sport athletes.
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- 2024
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75. Transit Timing Variations in the three-planet system: TOI-270
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Kaye, Laurel, Vissapragada, Shreyas, Gunther, Maximilian N., Aigrain, Suzanne, Mikal-Evans, Thomas, Jensen, Eric L. N., Parviainen, Hannu, Pozuelos, Francisco J., Abe, Lyu, Acton, Jack S., Agabi, Abdelkrim, Alves, Douglas R., Anderson, David R., Armstrong, David J., Barkaoui, Khalid, Barragan, Oscar, Benneke, Bjorn, yd, Patricia T. Bo, Brahm, Rafael, Bruni, Ivan, Bryant, Edward M., Burleigh, Matthew R., Casewell, Sarah L., Ciardi, David, Cloutier, Ryan, Collins, Karen A., Collins, Kevin I., Conti, Dennis M., Crossfield, Ian J. M., Crouzet, Nicolas, Daylan, Tansu, Dragomir, Diana, Dransfield, Georgina, abrycky, Daniel F, Fausnaugh, Michael, Fuuresz, Gabor, Gan, Tianjun, Gill, Samuel, Gillon, Michael, Goad, Michael R, Gorjian, Varoujan, Greklek-McKeon, Michael, Guerrero, Natalia, Guillot, Tristan, Jehin, Emmanuel, Jenkins, J. S., Lendl, Monika, Kamler, Jacob, Kane, Stephen R., Kielkopf, John F., Kunimoto, Michelle, Marie-Sainte, Wenceslas, McCormac, James, Mekarnia, Djamel, Morales, Farisa Y., Moyano, Maximiliano, Palle, Enric, Parmentier, Vivien, Relles, Howard M., Schmider, Francois-Xavier, Schwarz, Richard P., Seager, S., Smith, Alexis M. S., Tan, Thiam-Guan, Taylor, Jake, Triaud, Amaury H. M. J., Twicken, Joseph D., Udry, Stephane, Vines, J. I., Wang, Gavin, Wheatley, Peter J., and Winn, Joshua N.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We present ground and space-based photometric observations of TOI-270 (L231-32), a system of three transiting planets consisting of one super-Earth and two sub-Neptunes discovered by TESS around a bright (K-mag=8.25) M3V dwarf. The planets orbit near low-order mean-motion resonances (5:3 and 2:1), and are thus expected to exhibit large transit timing variations (TTVs). Following an extensive observing campaign using 8 different observatories between 2018 and 2020, we now report a clear detection of TTVs for planets c and d, with amplitudes of $\sim$10 minutes and a super-period of $\sim$3 years, as well as significantly refined estimates of the radii and mean orbital periods of all three planets. Dynamical modeling of the TTVs alone puts strong constraints on the mass ratio of planets c and d and on their eccentricities. When incorporating recently published constraints from radial velocity observations, we obtain masses of $M_{\mathrm{b}}=1.48\pm0.18\,M_\oplus$, $M_{c}=6.20\pm0.31\,M_\oplus$ and $M_{\mathrm{d}}=4.20\pm0.16\,M_\oplus$ for planets b, c and d, respectively. We also detect small, but significant eccentricities for all three planets : $e_\mathrm{b} =0.0167\pm0.0084$, $e_{c} =0.0044\pm0.0006$ and $e_{d} = 0.0066\pm0.0020$. Our findings imply an Earth-like rocky composition for the inner planet, and Earth-like cores with an additional He/H$_2$O atmosphere for the outer two. TOI-270 is now one of the best-constrained systems of small transiting planets, and it remains an excellent target for atmospheric characterization., Comment: 22 pages, 7 figures
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- 2023
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76. An updated mass-radius analysis of the 2017-2018 NICER data set of PSR J0030+0451
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Vinciguerra, Serena, Salmi, Tuomo, Watts, Anna L., Choudhury, Devarshi, Riley, Thomas E., Ray, Paul S., Bogdanov, Slavko, Kini, Yves, Guillot, Sebastien, Chakrabarty, Deepto, Ho, Wynn C. G., Huppenkothen, Daniela, Morsink, Sharon M., and Wadiasingh, Zorawar
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics ,Nuclear Theory - Abstract
In 2019 the NICER collaboration published the first mass and radius inferred for PSR J0030+0451, thanks to NICER observations, and consequent constraints on the equation of state characterising dense matter. Two independent analyses found a mass of $\sim 1.3-1.4\,\mathrm{M_\odot}$ and a radius of $\sim 13\,$km. They also both found that the hot spots were all located on the same hemisphere, opposite to the observer, and that at least one of them had a significantly elongated shape. Here we reanalyse, in greater detail, the same NICER data set, incorporating the effects of an updated NICER response matrix and using an upgraded analysis framework. We expand the adopted models and jointly analyse also XMM-Newton data, which enables us to better constrain the fraction of observed counts coming from PSR J0030+0451. Adopting the same models used in previous publications, we find consistent results, although with more stringent inference requirements. We also find a multi-modal structure in the posterior surface. This becomes crucial when XMM-Newton data is accounted for. Including the corresponding constraints disfavors the main solutions found previously, in favor of the new and more complex models. These have inferred masses and radii of $\sim [1.4 \mathrm{M_\odot}, 11.5$ km] and $\sim [1.7 \mathrm{M_\odot}, 14.5$ km], depending on the assumed model. They display configurations that do not require the two hot spots generating the observed X-rays to be on the same hemisphere, nor to show very elongated features, and point instead to the presence of temperature gradients and the need to account for them., Comment: 35 pages, 11 figures, 7 tables
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- 2023
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77. Atmospheric Effects on Neutron Star Parameter Constraints with NICER
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Salmi, Tuomo, Vinciguerra, Serena, Choudhury, Devarshi, Watts, Anna L., Ho, Wynn C. G., Guillot, Sebastien, Kini, Yves, Dorsman, Bas, Morsink, Sharon M., and Bogdanov, Slavko
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Solar and Stellar Astrophysics ,Nuclear Theory - Abstract
We present an analysis of the effects of uncertainties in the atmosphere models on the radius, mass, and other neutron star parameter constraints for the NICER observations of rotation-powered millisecond pulsars. To date, NICER has applied the X-ray pulse profile modeling technique to two millisecond-period pulsars: PSR J0030+0451 and the high-mass pulsar PSR J0740+6620. These studies have commonly assumed a deep-heated, fully ionized hydrogen atmosphere model, although they have explored the effects of partial-ionization and helium composition in some cases. Here, we extend that exploration and also include new models with partially ionized carbon composition, externally heated hydrogen, and an empirical atmospheric beaming parameterization to explore deviations in the expected anisotropy of the emitted radiation. None of the studied atmosphere cases have any significant influence on the inferred radius of PSR J0740+6620, possibly due to its X-ray faintness, tighter external constraints, and/or viewing geometry. In the case of PSR J0030+0451, both the composition and ionization state could significantly alter the inferred radius. However, based on the evidence (prior predictive probability of the data), partially ionized hydrogen and carbon atmospheres are disfavored. The difference in the evidence for ionized hydrogen and helium atmospheres is too small to be decisive for most cases, but the inferred radius for helium models trends to larger sizes around or above 14-15 km. External heating or deviations in the beaming that are less than $5\,\%$ at emission angles smaller than 60 degrees, on the other hand, have no significant effect on the inferred radius., Comment: 26 pages, 12 figures (2 of which are figure sets), 3 tables. Published in ApJ
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- 2023
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78. Highly depleted alkali metals in Jupiter's deep atmosphere
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Bhattacharya, Ananyo, Li, Cheng, Atreya, Sushil K., Steffes, Paul G., Levin, Steven M., Bolton, Scott J., Guillot, Tristan, Gupta, Pranika, Ingersoll, Andrew P., Lunine, Jonathan I., Orton, Glenn S., Oyafuso, Fabiano A., Waite, J. Hunter, Belloti, Amadeo, and Wong, Michael H.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Water and ammonia vapors are known to be the major sources of spectral absorption at pressure levels observed by the microwave radiometer (MWR) on Juno. However, the brightness temperatures and limb darkening observed by the MWR at its longest wavelength channel of 50 cm (600 MHz) in the first 9 perijove passes indicate the existence of an additional source of opacity in the deep atmosphere of Jupiter (pressures beyond 100 bar). The absorption properties of ammonia and water vapor, and their relative abundances in Jupiter's atmosphere do not provide sufficient opacity in deep atmosphere to explain the 600 MHz channel observation. Here we show that free electrons due to the ionization of alkali metals, i.e. sodium, and potassium, with sub-solar metallicity [M/H] (log based 10 relative concentration to solar) in the range of [M/H] = -2 to [M/H] = -5 can provide the missing source of opacity in the deep atmosphere. If the alkali metals are not the source of additional opacity in the MWR data, then their metallicity at 1000 bars can only be even lower. The upper bound of -2 on the metallicity of the alkali metals contrasts with the other heavy elements -- C, N, S, Ar, Kr, and Xe -- which are all enriched relative to their solar abundances having a metallicity of approximately +0.5., Comment: This manuscript has been accepted for publication in The Astrophysical Journal Letters. The final version of the paper will be available in the published journal. This arXiv version is provided for informational purposes
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- 2023
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79. Thermonuclear Type-I X-ray Bursts and Burst Oscillations from the Eclipsing AMXP Swift J1749.4-2807
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Albayati, A. C., Bult, P., Altamirano, D., Chenevez, J., Guillot, S., Güver, T., Jaisawal, G. K., Malacaria, C., Mancuso, G. C., Marino, A., Ng, M., Sanna, A., and Strohmayer, T. E.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Swift J1749.4-2807 is the only known eclipsing accreting millisecond X-ray pulsar. In this paper, we report on 7 thermonuclear (Type-I) X-ray bursts observed by NICER during its 2021 outburst. The first 6 bursts show slow rises and long decays, indicative of mixed H/He fuel, whereas the last burst shows fast rise and decay, suggesting He-rich fuel. Time-resolved spectroscopy of the bursts revealed typical phenomenology (i.e., an increase in black body temperature during the burst rise, and steady decrease in the decay), however they required a variable $N_\mathrm{H}$. We found that the values of $N_\mathrm{H}$ during the bursts were roughly double those found in the fits of the persistent emission prior to each burst. We interpret this change in absorption as evidence of burst-disc interaction, which we observe due to the high inclination of the system. We searched for burst oscillations during each burst and detected a signal in the first burst at the known spin frequency of the neutron star (517.92 Hz). This is the first time burst oscillations have been detected from Swift J1749.4-2807. We further find that each X-ray burst occurs on top of an elevated persistent count rate. We performed time-resolved spectroscopy on the combined data of the bursts with sufficient statistics (i.e., the clearest examples of this phenomenon) and found that the black body parameters evolve to hotter temperatures closer to the onset of the bursts. We interpret this as a consequence of an unusual marginally stable burning process similar to that seen through mHz QPOs., Comment: accepted for publication in MNRAS, 12 pages, 11 figures
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- 2023
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80. Tormund's return: Hints of quasi-periodic eruption features from a recent optical tidal disruption event
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Quintin, E., Webb, N. A., Guillot, S., Miniutti, G., Kammoun, E. S., Giustini, M., Arcodia, R., Soucail, G., Clerc, N., Amato, R., and Markwardt, C. B.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Quasi-periodic eruptions (QPEs) are repeating thermal X-ray bursts associated with accreting massive black holes, the precise underlying physical mechanisms of which are still unclear. We present a new candidate QPE source, AT 2019vcb (nicknamed Tormund by the ZTF collaboration), which was found during an archival search for QPEs in the XMM-Newton archive. It was first discovered in 2019 as an optical tidal disruption event (TDE) at $z=0.088$, and its X-ray follow-up exhibited QPE-like properties. Our goals are to verify its robustness as QPE candidate and to investigate its properties to improve our understanding of QPEs. We performed a detailed study of the X-ray spectral behaviour of this source over the course of the XMM-Newton archival observation. We also report on recent Swift and NICER follow-up observations to constrain the source's current activity and overall lifetime, as well as an optical spectral follow-up. The first two Swift detections and the first half of the 30 ks XMM-Newton exposure of Tormund displayed a decaying thermal emission typical of an X-ray TDE. However, the second half of the exposure showed a dramatic rise in temperature (from 53 to 114 eV) and 0.2-2 keV luminosity (from $3.2\times10^{42}$ to $1.2\times10^{44}$ erg s$^{-1}$). The late-time NICER follow-up indicates that the source is still X-ray bright more than three years after the initial optical TDE. Although only a rise phase was observed, Tormund's strong similarities with a known QPE source (eRO-QPE1) and the impossibility to simultaneously account for all observational features with alternative interpretations allow us to classify Tormund as a candidate QPE. If confirmed as a QPE, it would further strengthen the observational link between TDEs and QPEs. It is also the first QPE candidate for which an associated optical TDE was directly observed, constraining the formation time of QPEs., Comment: Accepted for publication in A&A, 20 pages, 17 figures
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- 2023
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81. Native defect association in beta-Ga2O3 enables room-temperature p-type conductivity
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Chi, Zeyu, Sartel, Corinne, Zheng, Yunlin, Modak, Sushrut, Chernyak, Leonid, Schaefer, Christian M, Padilla, Jessica, Santiso, Jose, Ruzin, Arie, Goncalves, Anne-Marie, von Bardeleben, Jurgen, Guillot, Gerard, Dumont, Yves, Perez-Tomas, Amador, and Chikoidze, Ekaterine
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Condensed Matter - Materials Science - Abstract
The room temperature hole conductivity of the ultra wide bandgap semiconductor beta Ga2O3 is a pre-requisite for developing the next-generation electronic and optoelectronic devices based on this oxide. In this work, high-quality p-type beta-Ga2O3 thin films grown on r-plane sapphire substrate by metalorganic chemical vapor deposition (MOCVD) exhibit Rho = 50000Ohm.cm resistivity at room temperature. A low activation energy of conductivity as Ea2=170 meV was determined, associated to the oxygen - gallium native acceptor defect complex. Further, taking advantage of cation (Zn) doping, the conductivity of Ga2O3:Zn film was remarkably increased by three orders of magnitude, showing a long-time stable room-temperature hole conductivity with the conductivity activation energy of around 86 meV., Comment: 21pages; 9figures
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- 2023
82. Associations of DHEA(S) with negative and positive affect in people who smoke daily with elevated and low depression symptoms: A pilot laboratory study
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Pang, Raina D, Tucker, Chyna J, Guillot, Casey R, Belcher, Britni, and Kirkpatrick, Matthew G
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Depression ,Mental Health ,Tobacco ,Tobacco Smoke and Health ,Prevention ,Clinical Research ,Humans ,Dehydroepiandrosterone ,Dehydroepiandrosterone Sulfate ,Smoking Cessation ,Smoking ,Cigarette smoking ,DHEA(S) ,Depression symptoms ,Negative affect ,People who smoke ,Positive affect ,Public Health and Health Services ,Psychology ,Substance Abuse - Abstract
BackgroundIndividuals with depression symptoms have a harder time quitting smoking. High negative affect and low positive affect are core depression symptoms and arise following cigarette abstinence. Investigating associations of biological markers with negative and positive affect may provide valuable information about factors relevant to smoking cessation in individuals with elevated depression symptoms.MethodsDepression symptoms were measured at a baseline session. Participants then completed two counterbalanced experimental sessions (non-abstinent, abstinent) and completed measures of positive and negative affect, and provided saliva samples. Saliva samples were assayed at the Salimetrics' SalivaLab (Carlsbad, CA) using the Salimetrics Salivary Dehydroepiandrosterone (DHEA) Assay Kit (Cat. No. 1-1202) and Dehydroepiandrosterone-sulfate (DHEA-S) Assay Kit (Cat. No. 1-1252).ResultsThere were no main or interactive associations of DHEA with negative affect. However, there were significant DHEAS × experimental session and DHEAS × experimental session × depression symptom level interactions with negative affect. In the high depression symptom group, DHEAS positively associated with negative affect during the non-abstinent experimental session, but DHEAS negatively associated with negative affect during the abstinent experimental session. There were no associations of DHEA or DHEAS with positive affect.ConclusionThis study found that DHEAS negatively associated with negative affect during cigarette abstinence in individuals with elevated depression symptoms. This is important as high negative affect during cigarette abstinence may result in a return to smoking.
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- 2023
83. Seasonal and climatic influence on respiratory infections in children with cystic fibrosis
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Mésinèle, Julie, Ruffin, Manon, Guillot, Loïc, Boëlle, Pierre-Yves, and Corvol, Harriet
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- 2024
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84. The outcomes of robot-assisted surgery in the treatment of neurogenic lower urinary tract dysfunctions: a systematic review and meta-analysis
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Geretto, Paolo, De Cillis, Sabrina, Osman, Nadir I., Cancrini, Fabiana, Culha, Mehmet Gokhan, Doizi, Steeve, Guillot-Tantay, Cyrille, Herve, Francois, Przydacz, Mikolaj, Raison, Nicholas, Fernandez, Antonio Tienza, Tutolo, Manuela, Vale, Luis, and Phé, Véronique
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- 2024
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85. Leveraging weak complementary labels enhances semantic segmentation of hepatocellular carcinoma and intrahepatic cholangiocarcinoma
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Hägele, Miriam, Eschrich, Johannes, Ruff, Lukas, Alber, Maximilian, Schallenberg, Simon, Guillot, Adrien, Roderburg, Christoph, Tacke, Frank, and Klauschen, Frederick
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- 2024
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86. Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity
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Mochel, Jonathan P., Ward, Jessica L., Blondel, Thomas, Kundu, Debosmita, Merodio, Maria M., Zemirline, Claudine, Guillot, Emilie, Giebelhaus, Ryland T., de la Mata, Paulina, Iennarella-Servantez, Chelsea A., Blong, April, Nam, Seo Lin, Harynuk, James J., Suchodolski, Jan, Tvarijonaviciute, Asta, Cerón, José Joaquín, Bourgois-Mochel, Agnes, Zannad, Faiez, Sattar, Naveed, and Allenspach, Karin
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- 2024
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87. Unraveling the pathological biomineralization of monosodium urate crystals in gout patients
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Rodriguez-Navarro, Carlos, Elert, Kerstin, Ibañez-Velasco, Aurelia, Monasterio-Guillot, Luis, Andres, Mariano, Sivera, Francisca, Pascual, Eliseo, and Ruiz-Agudo, Encarnación
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- 2024
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88. CDK4/6 inhibition enhances T-cell immunotherapy on hepatocellular carcinoma cells by rejuvenating immunogenicity
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Cai, Xiurong, Yin, Guo, Chen, Shuai, Tacke, Frank, Guillot, Adrien, and Liu, Hanyang
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- 2024
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89. Cassini spacecraft reveals global energy imbalance of Saturn
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Wang, Xinyue, Li, Liming, Jiang, Xun, Fry, Patrick M., West, Robert A., Nixon, Conor A., Guan, Larry, Karandana G, Thishan D., Albright, Ronald, Colwell, Joshua E., Guillot, Tristan, Hofstadter, Mark D., Kenyon, Matthew E., Mallama, Anthony, Perez-Hoyos, Santiago, Sanchez-Lavega, Agustin, Simon, Amy A., Wenkert, Daniel, and Zhang, Xi
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- 2024
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90. Human local field potentials in motor and non-motor brain areas encode upcoming movement direction
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Combrisson, Etienne, Di Rienzo, Franck, Saive, Anne-Lise, Perrone-Bertolotti, Marcela, Soto, Juan L. P., Kahane, Philippe, Lachaux, Jean-Philippe, Guillot, Aymeric, and Jerbi, Karim
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- 2024
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91. Towards efficient motor imagery interventions after lower-limb amputation
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Saruco, Elodie, Saimpont, Arnaud, Di Rienzo, Franck, De Witte, Benjamin, Laroyenne, Isabelle, Matéo, Fanny, Lapenderie, Marion, Solard, Sarah Goutte, Perretant, Isabelle, Frenot, Charlotte, Jackson, Philip L., and Guillot, Aymeric
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- 2024
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92. Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study
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Przydacz, Mikolaj, Osman, Nadir, De Cillis, Sabrina, Guillot-Tantay, Cyrille, Herve, Francois, Hüsch, Tanja, Illiano, Ester, Fernandez, Antonio Tienza, Tutolo, Manuela, Vale, Luis, Culha, Mehmet Gokhan, Cancrini, Fabiana, Doizi, Steeve, Geretto, Paolo, Raison, Nicholas, Goldman, Howard B., Chlosta, Piotr, and Phe, Veronique
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- 2024
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93. Researcher and patient experiences of co-presenting research to people living with systemic sclerosis at a patient conference: content analysis of interviews
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Wurz, Amanda, Ellis, Kelsey, Nordlund, Julia, Carrier, Marie-Eve, Cook, Vanessa, Gietzen, Amy, Adams, Claire, Nassar, Elsa-Lynn, Rice, Danielle B., Fortune, Catherine, Guillot, Genevieve, Mieszczak, Tracy, Richard, Michelle, Sauve, Maureen, and Thombs, Brett D.
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- 2024
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94. Spatial multi-criteria decision analysis for the selection of sentinel regions in tick-borne disease surveillance
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Guillot, C., Aenishaenslin, C., Acheson, E. S., Koffi, J., Bouchard, C., and Leighton, P. A.
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- 2024
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95. Sialic acids cleavage induced by elastin-derived peptides impairs the interaction between insulin and its receptor in adipocytes 3T3-L1
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Guillot, Alexandre, Toussaint, Kevin, Ebersold, Lucrece, ElBtaouri, Hassan, Thiebault, Emilie, Issad, Tarik, Peiretti, Franck, Maurice, Pascal, Sartelet, Hervé, Bennasroune, Amar, Martiny, Laurent, Dauchez, Manuel, Duca, Laurent, Durlach, Vincent, Romier, Béatrice, Baud, Stéphanie, and Blaise, Sébastien
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- 2024
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96. Patient with a novel syndrome with multiple benign hepatic lesions and extrahepatic neoplasms
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Wilken, Silvana, Thevathasan, Tharusan, Kamali, Can, Guillot, Adrien, Ihlow, Jana, Fehrenbach, Uli, Danyel, Magdalena, Pratschke, Johann, Tacke, Frank, and Krenzien, Felix
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- 2024
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97. Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?
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Contreras-Toledo, Débora, Jiménez-Fonseca, Paula, López, Carlos López, Montes, Ana Fernández, López Muñoz, Ana María, Vázquez Rivera, Francisca, Alonso, Vicente, Alcaide, Julia, Salvà, Francesc, Covela Rúa, Marta, Guillot, Mónica, Martín Carnicero, Alfonso, Jimeno Mate, Raquel, Cameselle García, Soledad, Asensio Martínez, Elena, González Astorga, Beatriz, Fernandez-Diaz, Amaya B., González Villaroel, Paula, Virgili Manrique, Anna C., Melián Sosa, Marcos, Alonso, Beatriz, Cousillas Castiñeiras, Antia, Castañón López, Carmen, Aparicio, Jorge, and Carmona-Bayonas, Alberto
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- 2024
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98. Structural and mechanistic basis for RiPP epimerization by a radical SAM enzyme
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Kubiak, Xavier, Polsinelli, Ivan, Chavas, Leonard M. G., Fyfe, Cameron D., Guillot, Alain, Fradale, Laura, Brewee, Clémence, Grimaldi, Stéphane, Gerbaud, Guillaume, Thureau, Aurélien, Legrand, Pierre, Berteau, Olivier, and Benjdia, Alhosna
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- 2024
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99. Dermatophytes and mammalian hair: aspects of the evolution of Arthrodermataceae
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Tang, Chao, Zhou, Xin, Guillot, Jacques, Wibbelt, Gudrun, Deng, Shuwen, Kandemir, Hazal, Gräser, Yvonne, Feng, Peiying, Kang, Yingqian, and de Hoog, G. Sybren
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- 2024
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100. TOI-1130: A photodynamical analysis of a hot Jupiter in resonance with an inner low-mass planet
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Korth, J., Gandolfi, D., Šubjak, J., Howard, S., Ataiee, S., Collins, K. A., Quinn, S. N., Mustill, A. J., Guillot, T., Lodieu, N., Smith, A. M. S., Esposito, M., Rodler, F., Muresan, A., Abe, L., Albrecht, S. H., Alqasim, A., Barkaoui, K., Beck, P. G., Burke, C. J., Butler, R. P., Conti, D. M., Collins, K. I., Crane, J. D., Dai, F., Deeg, H. J., Evans, P., Grziwa, S., Hatzes, A. P., Hirano, T., Horne, K., Huang, C. X., Jenkins, J. M., Kabáth, P., Kielkopf, J. F., Knudstrup, E., Latham, D. W., Livingston, J., Luque, R., Mathur, S., Murgas, F., Osborne, H. L. M., Pallé, E., Persson, C. M., Rodriguez, J. E., Rose, M., Rowden, P., Schwarz, R. P., Seager, S., Serrano, L. M., Sha, L., Shectman, S. A., Shporer, A., Srdoc, G., Stockdale, C., Tan, T. G., Teske, J. K., Van Eylen, V., Vanderburg, A., Vanderspek, R., Wang, S. X., and Winn, J. N.
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
The TOI-1130 is a known planetary system around a K-dwarf consisting of a gas giant planet, TOI-1130 c, on an 8.4-day orbit, accompanied by an inner Neptune-sized planet, TOI-1130 b, with an orbital period of 4.1 days. We collected precise radial velocity (RV) measurements of TOI-1130 with the HARPS and PFS spectrographs as part of our ongoing RV follow-up program. We perform a photodynamical modeling of the HARPS and PFS RVs, and transit photometry from the Transiting Exoplanet Survey Satellite (TESS) and the TESS Follow-up Observing Program. We determine the planet masses and radii of TOI-1130 b and TOI-1130 c to be Mb = 19.28 $\pm$ 0.97 M$_\oplus$ and Rb = 3.56 $\pm$ 0.13 R$_\oplus$, and Mc = 325.59 $\pm$ 5.59 M$_\oplus$ and Rc = 13.32+1.55-1.41 R$_\oplus$, respectively. We spectroscopically confirm TOI-1130 b that was previously only validated. We find that the two planets orbit with small eccentricities in a 2:1 resonant configuration. This is the first known system with a hot Jupiter and an inner lower mass planet locked in a mean-motion resonance. TOI-1130 belongs to the small yet increasing population of hot Jupiters with an inner low-mass planet that challenges the pathway for hot Jupiter formation. We also detect a linear RV trend possibly due to the presence of an outer massive companion., Comment: 19 pages, Accepted to A&A
- Published
- 2023
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