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52. Responsible metrics for evaluating research quality

Author

Salholz-Hillel, M, Franzen, D, Grabitz, P, Holst, M, Carlisle, B, Saksone, L, and Strech, D

Subjects
ddc: 610, open and transparent research, increasing value and reducing waste, 610 Medical sciences, Medicine, responsible metrics, reproducibility
Abstract

The quality of research, researchers, and research institutions is traditionally assessed with metrics such as journal impact factor, H-index, and number of publications. These metrics affect research choices (e.g., whether and how a researcher pursues a question), career success of individual researchers[for full text, please go to the a.m. URL], 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)

Published
2021
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90. Abstracts of scientific papers second international symposium on central nervous system monitoring: September 8–9, 1989 Gmunden, Austria

Author

Gaab, M. R., Trost, H. A., Lorenz, M., Seegers, K., Heuser, D., Fitch, W., Baethmann, A., Speckmann, E. -J., Lehmenkühler, A., Pöppelmann, Th., Bingmann, D., Rabow, L., Bergenheim, T., Bålfors, Eva, Urban, G., Keplinger, F., Kohl, F., Kuttner, H., Jobst, G., Pittner, F., Schalkhammer, T., Mann-Buxbaum, E., Litscher, G., Steiler, E., Pfurtschcller, G., Schwarz, G., Hinrichs, H., Feistner, H., Künkel, H., Wieser, H. G., Isler, P., Witztum, A., Siegel, A., Merles, N., Möllmann, M., Penner, M., Schoeppner, H., Hohenberger, K., Daub, D., Freye, E., Grabitz, K., Sandmann, W., Haass, A., Ladurner, G., Teasdale, G., Weis, M., Hilz, M. J., Claus, D., Neundörfer, B., Druschky, K. F., Litscher, G., Pfurtscheller, G., Heinze, H.-J, Künkcl, H., Symon, L., Cooper, Gough, Rampil, I. J., Bosco, M., Adducci, E., Gualtieri, E., Amato, A., Lacava, E., Mascia, A., Bonomo, V., Dinkel, M., Kamp, H.-D, Schweiger, H., Jaksche, H., Schwerdtfeger, K., Loew, F., Rath, S. A., Klein, H. J., Kühn, J., Fritz, W., Thiel, A., Russ, W., Hcmpelmann, G., Morawetz, R. F., Schlager, A., Lugcr, Th. J., Vajsar, J., Hopkins, Anne J., Ronen, G. M., Kuppe, H., Porte, T., Dannenberger, R., Götz, C., Adt, M., Schmucker, P., Landi, A., Colombo, F., De Luca, G. P., Fornezza, U., Benedctti, A., Bruno, R., Zamparctti, N., Engelhardt, W., Drösler, S., Dierks, T., Maurer, K., Hecht, U., Lehmkuhl, P., Pichlmayr, I., Cheng-hui, Li, Shi-ao, Jin, Cheng-hui, Li, Shi-ao, Jin, Theissen, J., Zander, J., Moberg, D., Bell, R., Miller, S. B., Pohl, S., Hühnefeld, D., Henries, H.-J, Jantzen, J.-P, Eberle, B., Dick, W., Wallenfang, T., Fuzes, I., Geissler, C., Schregel, W., Cunitz, G., Fomezza, U., Volpin, L., Zamperetti, N., Demo, P., Digito, A., Barbacini, S., Zamperetti, N., and Lacquaniti, L.

Published
1990
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91. Prevalence of and risk factors for perioperative arrhythmias in neonates and children after cardiopulmonary bypass: continuous holter monitoring before and for three days after surgery

Author

Vazquez-Jimenez Jaime F, Grabitz Ralph G, Kreitz Suzanna, Grosse-Wortmann Lars, Messmer Bruno J, von Bernuth Goetz, and Seghaye Marie-Christine

Subjects
Surgery, RD1-811, Anesthesiology, RD78.3-87.3
Abstract

Abstract Background A comprehensive evaluation of postoperative arrhythmias following surgery for congenital heart disease by continuous Holter monitoring has not been carried out. We aimed, firstly, to establish the time course of pre- and early postoperative arrhythmias by beat-to-beat analysis following cardiopulmonary bypass and, secondly, to examine which surgical procedures present risk factors for specific arrhythmias. Methods 494 consecutive patients, including 96 neonates, were studied with serial 24-hour Holter electrocardiograms before as well as uninterruptedly during the first 72 hours after surgery and prior to discharge. Results Within 24 hours of surgery 59% of the neonates and 79% of the older children developed arrhythmias. Junctional ectopic tachycardia occurred in 9% of neonates and 5% of non-neonates and ventricular tachycardia in 3% and 15%, respectively. For neonates, male sex and longer cross-clamping time independently increased the risk for arrhythmias (odds ratios 2.83 and 1.96/minute, respectively). Ventricular septal defect repair was a strong risk factor for junctional ectopic tachycardia in neonates and in older children (odds ratios 18.8 and 3.69, respectively). For infants and children, older age (odds ratio 1.01/month) and closure of atrial septal defects (odds ratio 2.68) predisposed to arrhythmias of any type. Conclusions We present the largest cohort of neonates, infants and children that has been prospectively studied for the occurrence of arrhythmias after cardiac surgery. Postoperative arrhythmias are a frequent and transient phenomenon after cardiopulmonary bypass, provoked both by mechanical irritation of the conduction system and by humoral factors.

Published
2010
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94. Development of an Instrument for Preoperative Prediction of Adverse Discharge in Patients Scheduled for Cardiac Surgery.

Author

Gosling, Andre F., Hammer, Maximilian, Grabitz, Stephanie, Wachtendorf, Luca J., Katsiampoura, Anastasia, Murugappan, Kadhiresan R., Sehgal, Sankalp, Khabbaz, Kamal R., Mahmood, Feroze, and Eikermann, Matthias

Abstract

Inability of home discharge occurs in nearly a third of patients undergoing cardiac surgery and is associated with increased mortality. The authors aimed to evaluate the incidence and risk factors for adverse discharge disposition (ADD) after cardiac surgery and develop a prediction tool for preoperative risk assessment. This retrospective cohort study included adult patients undergoing cardiac surgery between 2010 and 2018. The primary outcome was ADD, defined as in-hospital mortality, discharge to a skilled nursing facility, or transfer to a long-term care hospital. The authors created a prediction tool using stepwise backward logistic regression and used 5-fold and leave-one-out cross-validation. University hospital network. Adult patients living at home prior to surgery, who underwent coronary artery bypass grafting and/or valve procedures at the authors' institution. None. A total of 3,760 patients were included in the final study cohort. The observed rate of ADD was 33.3%. The prediction model showed good discrimination and accuracy, with C-statistic of 0.78 (95% confidence interval [CI] 0.76-0.79) and unmodified Brier score of 0.177 (reliability 0.001). The final model comprised 14 predictors. Patients who experienced ADD were more likely to be older, of female sex, to have had higher length of hospital stay prior to surgery, and to have undergone emergency surgery. The authors present an instrument for prediction of loss of the ability to live independently in patients undergoing cardiac surgery. The authors' score may be useful in identifying high-risk patients such that earlier coordination of care can be initiated in this vulnerable patient population. [ABSTRACT FROM AUTHOR]

Published
2021
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98. Circulation/Cardiology

Author

Grabitz, R. G., Coe, J. Y., Chen, R., Timinsky, J., von Bernuth, G., Yu, Xiang-Qing, Feet, Bjørn Aage, Moen, Atle, Ilves, Pilvi, Saugstad, Ola Didrik, Wetzel, R. C., Demirakça, S., Knothe, Ch., Hagel, K. J., Bauer, J., Kunovský P., Kováčikova L., Csader M., Siman J., Gutiérrez-Larraya F., Mendoza A., Velasco J. M., Zavanella C., Galindo A., Sánchez-Andrade R., Sánchez J. I., Melián A., and Mar F.

Published
1996
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99. Cardiac surgery

Author

Belli L. A., Carvalho W. B., Carvalho A. C. C., Longui C. A., Malluf M., Marone M. M. S., Seghaye, M. C., Duchateau, J., Bruniaux, J., Demontoux, S., Détruit, H., Bosson, C., Lecronier, G., Mokhfi, E., Serraf, A., Planché, C., Grabitz, R. G., Meyer, A., Redaelli, M., Hörnchen, H., Messmer, B. J., von Bernuth, G., Augusto, Pérez, Eduardo, Schnitzler, Pablo, Mices, Wippermann, C. -F., Eberie, B., Schmid, F. X., Humpl, T., Huth, R., Habermehl, P., Michel-Behnke, I., Schranz, D., Souza R. L., Gerstler J. G., Branco K. M. P. C., Jünemann, R., Kotlarek, F., Rauschning, K., and Rau, G.

Published
1996
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