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271 results on '"Govindarajan, Anand"'

58. A Pragmatic Non-Randomized Trial of Prehabilitation Prior to Cancer Surgery: Study Protocol and COVID-19-Related Adaptations

Author

Santa Mina, Daniel, primary, Sellers, Daniel, additional, Au, Darren, additional, Alibhai, Shabbir M. H., additional, Clarke, Hance, additional, Cuthbertson, Brian H., additional, Darling, Gail, additional, El Danab, Alaa, additional, Govindarajan, Anand, additional, Ladha, Karim, additional, Matthew, Andrew G., additional, McCluskey, Stuart, additional, Ng, Karen A., additional, Quereshy, Fayez, additional, Karkouti, Keyvan, additional, and Randall, Ian M., additional

Published
2021
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59. Evidence-Based Strategies for the Treatment of Peritoneal Malignancies during Health Care Resource Restriction: The COVID-19 Pandemic

Author

Shariff, Farhana, primary, Bischof, Danielle, additional, Govindarajan, Anand, additional, Prince, Rebecca, additional, Burkes, Ronald, additional, Haase, Erika, additional, Mack, Lloyd, additional, Temple, Walley, additional, Hebbard, Pamela, additional, Boulanger-Gobeil, Cindy, additional, Giacomantonio, Carman, additional, Brind’Amour, Alexandre, additional, Sidéris, Lucas, additional, Dubé, Pierre, additional, Hamilton, Trevor, additional, MacNeill, Andrea, additional, Bouchard-Fortier, Antoine, additional, Younan, Rami, additional, and McCart, Andrea, additional

Published
2020
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69. Evidence-Based Strategies for the Treatment of Peritoneal Malignancies during Health Care Resource Restriction: The COVID-19 Pandemic.

Author

Shariff, Farhana, Bischof, Danielle, Govindarajan, Anand, Prince, Rebecca, Burkes, Ronald, Haase, Erika, Mack, Lloyd, Temple, Walley, Hebbard, Pamela, Boulanger-Gobeil, Cindy, Giacomantonio, Carman, Brind'Amour, Alexandre, Sidéris, Lucas, Dubé, Pierre, Hamilton, Trevor, MacNeill, Andrea, Bouchard-Fortier, Antoine, Younan, Rami, and McCart, Andrea

Subjects
PERITONEAL cancer, COVID-19 pandemic, MEDICAL care, HOSPITAL size, ONCOLOGIC surgery, ONCOLOGISTS
Abstract

Background: The COVID-19 pandemic has put enormous pressure on hospital resources, and has affected all aspects of patient care. As operative volumes decrease, cancer surgeries must be triaged and prioritized with careful thought and attention to ensure maximal benefit for the maximum number of patients. Peritoneal malignancies present a unique challenge, as surgical management can be resource intensive, but patients have limited non-surgical treatment options. This review summarizes current data on outcomes and resource utilization to help inform decision-making and case prioritization in times of constrained health care resources. Methods: A rapid literature review was performed, examining surgical and non-surgical outcomes data for peritoneal malignancies. Narrative data synthesis was cross-referenced with relevant societal guidelines. Peritoneal malignancy surgeons and medical oncologists reviewed recommendations to establish a national perspective on case triage and mitigating treatment strategies. Results and Conclusions: Triage of peritoneal malignancies during this time of restricted health care resource is nuanced and requires multidisciplinary discussion with consideration of individual patient factors. Prioritization should be given to patients where delay may compromise resectability of disease, and where alternative treatment options are lacking. Mitigating strategies such as systemic chemotherapy and/or surgical deferral may be utilized with close surveillance for disease stability or progression, which may affect surgical urgency. Unique hospital capacity, and ability to manage the complex post-operative course for these patients must also be considered to ensure patient and system needs are aligned. [ABSTRACT FROM AUTHOR]

Published
2021
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70. The Chicago Consensus on Peritoneal Surface Malignancies: Management of Appendiceal Neoplasms.

Author

Chicago Consensus Working Group, Schuitevoerder, Darryl, Plana, Alejandro, Izquierdo, Francisco J., Votanopoulos, Konstantinos I., Cusack, James C., Bijelic, Lana, Cho, Clifford S., Gangi, Alexandra, Gilbert, Erin W., Goodman, Martin D., Govindarajan, Anand, Gushchin, Vadim, Ihemelandu, Chukwuemeka, Kelly, Kaitlyn J., Merkow, Ryan P., Pappas, Sam G., Abbott, Daniel E., Ahrendt, Steven A., and Al-kasspooles, Mazin

Abstract

The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of appendiceal neoplasms specifically related to the management of peritoneal surface malignancies. These guidelines are developed with input from leading experts including surgical oncologists, medical oncologists, pathologists, radiologists, palliative care physicians, and pharmacists. These guidelines recognize and address the emerging need for increased awareness in the appropriate management of peritoneal surface disease. They are not intended to replace the quest for higher levels of evidence. [ABSTRACT FROM AUTHOR]

Published
2020
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71. The Chicago Consensus on peritoneal surface malignancies: Management of appendiceal neoplasms.

Author

Schuitevoerder, Darryl, Plana, Alejandro, Izquierdo, Francisco J., Votanopoulos, Konstantinos I., Cusack, James C., Bijelic, Lana, Cho, Clifford S., Gangi, Alexandra, Gilbert, Erin W., Goodman, Martin D., Govindarajan, Anand, Gushchin, Vadim, Ihemelandu, Chukwuemeka, Kelly, Kaitlyn J., Merkow, Ryan P., Pappas, Sam G., Abbott, Daniel E., Ahrendt, Steven A., Al‐Kasspooles, Mazin, and Alpert, Lindsay

Subjects
TUMORS, CANCER, PALLIATIVE treatment, PHYSICIANS, PATHOLOGISTS, RESEARCH funding
Abstract

The Chicago Consensus Working Group provides multidisciplinary recommendations for the management of appendiceal neoplasms specifically related to the management of peritoneal surface malignancies. These guidelines are developed with input from leading experts, including surgical oncologists, medical oncologists, pathologists, radiologists, palliative care physicians, and pharmacists. These guidelines recognize and address the emerging need for increased awareness in the appropriate management of peritoneal surface disease. They are not intended to replace the quest for higher levels of evidence. [ABSTRACT FROM AUTHOR]

Published
2020
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76. A population-based matched cohort study examining the mortality and costs of patients with community-onset Clostridium difficile infection identified using emergency department visits and hospital admissions

Author

Nanwa, Natasha, primary, Sander, Beate, additional, Krahn, Murray, additional, Daneman, Nick, additional, Lu, Hong, additional, Austin, Peter C., additional, Govindarajan, Anand, additional, Rosella, Laura C., additional, Cadarette, Suzanne M., additional, and Kwong, Jeffrey C., additional

Published
2017
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80. Canadian Society of Surgical Oncology Annual Scientific MeetingReal-time electromagnetic navigation in breast-conserving surgery: clinical feasibility study on palpable tumoursIntraoperative margin assessment in wire-localized breast-conserving surgery: a population-level comparison of techniquesGlove and instrument handling in cancer surgery: a survey of surgeons’ beliefs and practicesPrognostic factors in determining the outcome of head and neck cutaneous melanomaImpact of time from initial biopsy to definitive excision when residual melanoma is presentTotal neoadjuvant therapy for pancreatic cancer: an institutional experienceMyosteatosis visible on preoperative CT scan is associated with reduced survival following resection of periampullary adenocarcinomas

Author

Gauvin, Gabrielle, primary, Laws, Alison, primary, Berger-Richardson, David, primary, Buchko, Kristyn, primary, Nadler, Ashlie, primary, Aubin, Jean-Michel, primary, Ungi, Tamas, additional, Yeo, Caitlin T., additional, Lasso, Andras, additional, Rudan, John, additional, Walker, Ross, additional, Fichtinger, Gabor, additional, Engel, C. Jay, additional, Brar, Mantaj S., additional, Bouchard-Fortier, Antoine, additional, Leong, Brad, additional, Quan, May Lynn, additional, Govindarajan, Anand, additional, Gladdy, Rebecca A., additional, McCart, J. Andrea, additional, Swallow, Carol J., additional, Pathak, K. Alok, additional, Ruth, Karen J., additional, Farma, Jeffrey, additional, Reddy, Sanjay, additional, Zih, Francis S.W., additional, Hoffman, John, additional, Sigurdson, Elin, additional, Al-manasra, Tariq, additional, Tobola, Elizabeth, additional, Salazar, Santiago, additional, Leugner, Derek, additional, Sutherland, Francis R., additional, Ball, Chad, additional, Dixon, Elijah, additional, Baracos, Vickie, additional, and Bathe, Oliver F., additional

Published
2016
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81. 586 Compliance With Removal of Urinary Catheter Guideline Recommendations Leads to Improved Outcome in Enhanced Recovery After Surgery (ERAS) Patients

Author

Okrainec, Allan, primary, Aarts, Mary-Anne, additional, Pearsall, Emily A., additional, Victor, J. Charles, additional, McKenzie, Marg, additional, Govindarajan, Anand, additional, Rotstein, Ori, additional, McCluskey, Stuart, additional, Conn, Lesley Gotlib, additional, and McLeod, Robin, additional

Published
2016
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83. Repeated faecal occult blood testing is associated with decreased advanced colorectal cancer risk: A population-based study.

Author

Antonova, Lilia, James, Paul D., Paszat, Lawrence, Rabeneck, Linda, Baxter, Nancy N., Tinmouth, Jill M., Yun, Lingsong, and Govindarajan, Anand

Subjects
RECTUM tumors, TUMOR prevention, COLON tumor prevention, COLON tumors, FECAL analysis, BLOOD testing, CONFIDENCE intervals, FECAL occult blood tests, LONGITUDINAL method, TUMOR classification, MATHEMATICAL variables, LOGISTIC regression analysis, RETROSPECTIVE studies, ODDS ratio, DIAGNOSIS, TUMOR risk factors, CANCER risk factors
Abstract

Objective To evaluate the association between repeated faecal occult blood testing and advanced colorectal cancer risk at population level in Canada. Methods A retrospective cohort study of all Ontario residents aged 56–74 diagnosed with colorectal cancer from 1 April 2007 to 31 March 2010, identified using health administrative data. The primary outcome was stage IV colorectal cancer, and primary exposure was faecal occult blood testing use within five years prior to colorectal cancer diagnosis. Patients were categorized into four mutually exclusive groups based on their exposure to faecal occult blood testing in the five years prior to colorectal cancer diagnosis: none, pre-diagnostic, repeated, and sporadic. Logistic regression was utilized to adjust for confounders. Results Of 7753 patients (median age 66, interquartile range 61–70, 62% male) identified, 1694 (22%) presented with stage I, 2056 (27%) with stage II, 2428 (31%) with stage III, and 1575 (20%) with stage IV colorectal cancer. There were 4092 (53%) with no record of prior faecal occult blood testing, 1485 (19%) classified as pre-diagnostic, 1693 (22%) as sporadic, and 483 (6%) as repeated faecal occult blood testing. After adjusting for confounders, patients who had repeated faecal occult blood testing were significantly less likely to present with stage IV colorectal cancer at diagnosis (Odds ratio 0.46, 95% Confidence Interval 0.34–0.62) than those with no prior faecal occult blood testing. Conclusions Repeated faecal occult blood testing is associated with a decreased risk of advanced colorectal cancer. Our findings support the use of organized screening programmes that employ repeated faecal occult blood testing to improve colorectal cancer outcomes at population level. [ABSTRACT FROM AUTHOR]

Published
2018
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98. The Economic Burden of Hospital-Acquired Clostridium difficileInfection: A Population-Based Matched Cohort Study

Author

Nanwa, Natasha, Kwong, Jeffrey C., Krahn, Murray, Daneman, Nick, Lu, Hong, Austin, Peter C., Govindarajan, Anand, Rosella, Laura C., Cadarette, Suzanne M., and Sander, Beate

Abstract

BACKGROUNDHigh-quality cost estimates for hospital-acquired Clostridium difficileinfection (CDI) are vital evidence for healthcare policy and decision-making.OBJECTIVETo evaluate the costs attributable to hospital-acquired CDI from the healthcare payer perspective.METHODSWe conducted a population-based propensity-score matched cohort study of incident hospitalized subjects diagnosed with CDI (those with the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, Canadacode A04.7) from January 1, 2003, through December 31, 2010, in Ontario, Canada. Infected subjects were matched to uninfected subjects (those without the code A04.7) on age, sex, comorbidities, geography, and other variables, and followed up through December 31, 2011. We stratified results by elective and nonelective admissions. The main study outcomes were up-to-3-year costs, which were evaluated in 2014 Canadian dollars.RESULTSWe identified 28,308 infected subjects (mean annual incidence, 27.9 per 100,000 population, 3.3 per 1,000 admissions), with a mean age of 71.5 years (range, 0–107 years), 54.0% female, and 8.0% elective admissions. For elective admission subjects, cumulative mean attributable 1-, 2-, and 3-year costs adjusted for survival (undiscounted) were $32,151 (95% CI, $28,192–$36,005), $34,843 ($29,298–$40,027), and $37,171 ($30,364–$43,415), respectively. For nonelective admission subjects, the corresponding costs were $21,909 ($21,221–$22,609), $26,074 ($25,180–$27,014), and $29,944 ($28,873–$31,086), respectively.CONCLUSIONSHospital-acquired CDI is associated with substantial healthcare costs. To the best of our knowledge, this study is the first CDI costing study to present longitudinal costs. New strategies may be warranted to mitigate this costly infectious disease.Infect Control Hosp Epidemiol2016;37:1068–1078

Published
2016
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99. SRU simulation: getting the properties right.

Author

GOVINDARAJAN, ANAND, HATCHER, NATHAN A., JONES, CLAYTON E., and WEILAND, G. SIMON

Subjects
*SULFUR, *MOLECULAR weights, *LIQUID sulfur
Abstract

The article describes the various properties of sulphur including its molecular formula and molecular weight, the vapour pressure of liquid sulphur and the viscosity of pure liquid sulphur.

Published
2016

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