Author: "Gopalan Nair Rajesh" - Searchworks@Jio Institute Digital Library Search Results

74 results on '"Gopalan Nair Rajesh"'

51. Double ventricular rupture after acute myocardial infarction: A rare case report

Author: Rajasekharan Sandeep, Rajesh Sadanadan, K.M. Kuriakose, Rajan Nair Shreetal, K T Sajeer, Gopalan Nair Rajesh, Vellani Haridasan, and Mangalath Narayanan Krishnan
Subjects: Male, medicine.medical_specialty, RD1-811, Heart Ventricles, medicine.medical_treatment, Case Report, Coronary Angiography, Revascularization, Diagnosis, Differential, Ventricular Septal Rupture, Electrocardiography, Pseudoaneurysm, medicine.artery, Internal medicine, medicine, Humans, Ventricular septal rupture, Diseases of the circulatory (Cardiovascular) system, Free-wall rupture, Myocardial infarction, Interventricular septum, cardiovascular diseases, medicine.diagnostic_test, business.industry, Electrocardiography in myocardial infarction, Middle Aged, medicine.disease, Surgery, medicine.anatomical_structure, Double mechanical rupture, Echocardiography, Right coronary artery, RC666-701, Angiography, Cardiology, cardiovascular system, Cardiology and Cardiovascular Medicine, business, Aneurysm, False
Abstract: A previously asymptomatic 53-year-old male presented 5 days after an acute anterior wall myocardial infarction, who was fibrinolytic naïve, with worsening dyspnea. Transthoracic echocardiographic evaluation revealed rupture of the interventricular septum and pseudoaneurysm of the left ventricle, confirmed by angiography. Coronary angiogram revealed multivessel disease. The patient underwent successful closure of ventricular septal rupture with repair of pseudoaneurysm and saphenous vein grafts to posterior descending branch of right coronary artery and obtuse marginal branch of left circumflex artery. Double ventricular ruptures following acute myocardial infarction are very rare with a reported incidence of 0.3% from various series in the revascularization era. They are also associated with exceedingly high mortality rates reaching up to 50%, even when intervened emergently.
Published: 2015

52. An unusual cause of acute cor pulmonale – Significance of the ‘continuous diaphragm sign’

Author: Vivek Pillai, Gopalan Nair Rajesh, Kader Muneer, C.G. Sajeev, Mangalath Narayanan Krishnan, and Sandeep Mohanan
Subjects: Adult, Diagnostic Imaging, Male, medicine.medical_specialty, RD1-811, Pneumomediastinum, Case Report, Chest pain, Diagnosis, Differential, Electrocardiography, Cor pulmonale, Pulmonary Heart Disease, Internal medicine, medicine.artery, medicine, Diseases of the circulatory (Cardiovascular) system, Animals, Humans, Columbidae, business.industry, Emergency department, medicine.disease, Pulmonary embolism, Diaphragm (structural system), Surgery, RC666-701, Pulmonary artery, Acute Disease, Etiology, Cardiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Hypersensitivity pneumonitis, Alveolitis, Extrinsic Allergic
Abstract: A patient presented with chest pain and clinical features of acute right heart failure. Initial work up revealed the presence of severe PAH. Acute pulmonary embolism is the commonest and most life-threatening cause for acute cor pulmonale. Even though the clinical picture suggested pulmonary embolism, a subtle sign was missed from the first chest X-ray taken in the emergency department. However on reanalysis the ‘continuous diaphragm sign’ later guided us towards the diagnosis. Our case represents one of the first reports of a rare etiology for acute cor pulmonale – hypersensitivity pneumonitis. Right ventricular dysfunction was caused by an acute rise in pulmonary artery pressures as well as by the compressive effects of pneumomediastinum. We emphasize the role played by a good quality chest X-ray early in the management of acute chest pain syndromes. However pulmonary embolism should be ruled out conclusively before redirecting attention to less malignant conditions.
Published: 2014

53. Device closure of pulmonary arteriovenous malformation using Amplatzer vascular plug II in hereditary hemorrhagic telangiectasia

Author: Gopalan Nair Rajesh, Chakanalil Govindan Sajeev, K T Sajeer, Mangalath Narayanan Krishnan, Vellani Haridasan, and Anishkumar Nair
Subjects: Male, medicine.medical_specialty, Cardiac Catheterization, RD1-811, Septal Occluder Device, medicine.medical_treatment, Vascular plug, Case Report, Pulmonary arteriovenous malformations, Pulmonary Artery, Young Adult, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, New device, Embolization, Pulmonary arteriovenous malformation, Telangiectasia, Brain abscess, Amplatzer vascular plug, business.industry, medicine.disease, Embolization, Therapeutic, Surgery, Hereditary hemorrhagic telangiectasia, Echocardiography, Pulmonary Veins, RC666-701, Arteriovenous Fistula, Radiography, Thoracic, Telangiectasia, Hereditary Hemorrhagic, Pulmonary hemorrhage, medicine.symptom, business, Cardiology and Cardiovascular Medicine, Tomography, X-Ray Computed, hormones, hormone substitutes, and hormone antagonists
Abstract: Pulmonary arteriovenous malformations (AVM) are very rare and carry the risk of cerebral thrombo-embolism, brain abscess or pulmonary hemorrhage. The Amplatzer vascular plug II (AVP II) is a new device, used for embolization of the pulmonary AVMs. We report a case of pulmonary AVM successfully managed by using AVP II in a patient with hereditary hemorrhagic telangiectasia (HHT).
Published: 2014

54. Intimo-intimal intussusception-circumferential aortic dissection: a rare mechanism of severe acute aortic regurgitation

Author: Nair Anishkumar, Chakanalil Govindan Sajeev, Gopalan Nair Rajesh, Mangalath Narayanan Krishnan, and K T Sajeer
Subjects: Aortic dissection, medicine.medical_specialty, business.industry, Regurgitation (circulation), medicine.disease, Internal medicine, medicine.artery, Cardiac tamponade, Descending aorta, Ascending aorta, cardiovascular system, medicine, Cardiology, Ventricular outflow tract, Radiology, Nuclear Medicine and imaging, Transthoracic echocardiogram, business, Aortic rupture
Abstract: A 55-year-old hypertensive man presented with acute onset of retrosternal pain and dyspnoea. On admission, he had tachypnoea, tachycardia and blood pressure of 190/100 mmHg. All peripheral pulses were normally felt. Auscultation revealed a long, early diastolic murmur along the left sternal border; the electrocardiogram showed normal sinus rhythm with no ischaemic changes. Chest X-ray revealed pulmonary congestion and mediastinal widening. An emergency transthoracic echocardiogram showed a dilated ascending aorta with a flap arising just above the aortic leaflet prolapsing into the left ventricular outflow tract producing severe aortic regurgitation (Fig. 1a–c; movie file 1, 2, 3). While awaiting emergency surgical repair, he collapsed and could not be resuscitated. In acute aortic dissection, disruption of intimal continuity with the circumferential intimal tear known as intimointimal intussusception is an unusual presentation. In untreated patients, acute dissection of the ascending aorta (Stanford type A) is associated with a 60 % mortality rate in the first 24 h and 90 % within 3 months [1]. In circumferential stripping of the intima in Stanford A dissection, the resultant intimal tube may prolapse either antegradely into the aortic lumen or retrogradely into the left ventricular cavity. Antegrade intussusception can result in neurologic disorders or features suggestive of pseudocoarctation by intermittent obstruction of the arch vessels and descending aorta, respectively. Retrograde intussusception towards the left ventricle may cause myocardial ischaemia by occluding the coronary vessels. Prolapse of leaflets and acute aortic insufficiency result from detachment of the aortic commissures, as in our case [2]. A number of sequelae such as haemorrhagic shock or cardiac tamponade secondary to aortic rupture, acute occlusion of major aortic branches and cardiogenic shock due to acute aortic regurgitation may be prevented by early diagnosis and surgical treatment. Magnetic resonance imaging and combined echocardiography (transthoracic and transesophageal) are presently advocated techniques for the detection of such aortic dissections. Valvular re-suspension is the surgical treatment of choice for severe aortic insufficiency due to the disturbance of the normal anatomic suspension of the aortic leaflets [1].
Published: 2014

55. HAEMODYNAMIC EFFECTS OF DOBUTAMINE IN PULMONARY HYPERTENSION SECONDARY TO MITRAL STENOSIS - A DOPPLER ECHO STUDY

Author: Bastian, Cicy, primary, Misiriya Kamarudheen Jameela, Raihanathul, additional, Kumar N, Sudhaya, additional, Khader S, Abdul, additional, and Gopalan Nair, Rajesh, additional
Published: 2016
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56. Isolated pulmonary valve endocarditis: A case report and review of literature

Author: Mangalath Narayanan Krishnan, M.P. Ranjith, Gopalan Nair Rajesh, Chakanalil Govindan Sajeev, V. Haridasan, K.F. Rajesh, and Cicy Bastian
Subjects: medicine.medical_specialty, Vegetation, Pulmonary valve, Normal delivery, business.industry, Pulmonary embolism, Clinical course, Case Report, medicine.disease, Surgery, Pulmonic valve endocarditis, medicine.anatomical_structure, Internal medicine, Antibiotic therapy, Infective endocarditis, medicine, Cardiology, Endocarditis, Cardiology and Cardiovascular Medicine, business
Abstract: Isolated pulmonic valve endocarditis is an uncommon clinical entity and is usually associated with intravenous drug abuse. We describe a case of isolated pulmonary valve endocarditis in a young woman with no apparent precipitating factors other than a history of recent normal delivery. During the clinical course she suffered a pulmonary embolism which could be managed conservatively and she was discharged after a 4-week course of antibiotic therapy. The literature on the isolated pulmonary valve endocarditis is reviewed.
Published: 2013

57. Intrapericardial schwannoma presenting as acute coronary syndrome

Author: Kudakachira Mathew Kuriakose, C.G. Sajeev, Vellani Haridasan, Gopalan Nair Rajesh, M.N. Krishnan, Deepak Raju, and Sadanandan Rajesh
Subjects: Adult, Acute coronary syndrome, medicine.medical_specialty, Computed tomography, Schwannoma, Diagnosis, Differential, Heart Neoplasms, Internal medicine, medicine, Humans, Acute Coronary Syndrome, Depression (differential diagnoses), medicine.diagnostic_test, biology, business.industry, Online video, medicine.disease, Troponin, Typical angina, biology.protein, Cardiology, Female, Radiology, business, Cardiology and Cardiovascular Medicine, Pericardium, Neurilemmoma
Abstract: [Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4] A 38-year-old female presented with typical angina, ST-segment depression in leads V1 to V4, and elevated troponin. Echocardiographic evaluation ( A , [Online Video 1][4]) and 64-slice computed tomography (CT) (B) showed a
Published: 2013

58. Left atrial appendage myxoma: 'the elephant's trunk'!

Author: K T Sajeer, Gopalan Nair Rajesh, and Mangalath Narayanan Krishnan
Subjects: Appendage, medicine.medical_specialty, biology, business.industry, Syncope (genus), Myxoma, Echogenicity, Anatomy, biology.organism_classification, medicine.disease, Trunk, Apex (geometry), Left atrial, Internal medicine, cardiovascular system, Cardiology, medicine, Left atrial enlargement, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business, Images in Cardiovascular Medicine
Abstract: A 72-year-old lady presented with history of recurrent episodes of syncope. Examination revealed a mid-diastolic murmur at apex. Electrocardiogram showed left atrial enlargement. Chest X-ray was normal. Transthoracic echocardiography showed a mobile left atrial mass of mixed echogenicity …
Published: 2013

59. A case of dyspnoea and visible neck pulsations

Author: Gopalan Nair Rajesh, Panakkal Jose Benny, and C.G. Sajeev
Subjects: Male, medicine.medical_specialty, Aortic Valve Insufficiency, Regurgitation (circulation), Ventricular tachycardia, New york heart association, Diagnosis, Differential, Acute onset, Internal medicine, medicine, Palpitations, Humans, cardiovascular diseases, Palpation, business.industry, Hypertrophic cardiomyopathy, Dilated cardiomyopathy, Middle Aged, medicine.disease, Dyspnea, Heart failure, cardiovascular system, Cardiology, Jugular Veins, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Venous Pressure, Neck
Abstract: A 48-year-old male patient with a history of New York Heart Association (NYHA) Class II dyspnoea for the last 2 years presented with acute onset breathlessness associated with orthopnoea and palpitations. The symptom aggravation was abrupt with simultaneous occurrence of both dyspnoea and palpitations. After medical stabilisation, the neck pulsations were as shown in online supplementary video 1. What is the most likely cardiac condition? 1. Aortic regurgitation 2. Congestive cardiac failure 3. Tricuspid regurgitation 4. Ventricular tachycardia The major clue here is to find out whether it is an arterial pulsation or a venous pulsation. Typically, an elevated jugular …
Published: 2016
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60. Echocardiographic assessment of right ventricular function in inferior wall myocardial infarction and angiographic correlation to proximal right coronary artery stenosis

Author: Deepak Nandan, Gopalan Nair Rajesh, C.G. Sajeev, Kadangot Babu, Desabandhu Vinayakumar, M.N. Krishnan, Kader Muneer, Vellani Haridasan, and Deepak Raju
Subjects: Male, medicine.medical_specialty, RD1-811, medicine.medical_treatment, Ventricular Dysfunction, Right, Infarction, Inferior Wall Myocardial Infarction, Coronary Angiography, Risk Assessment, Sensitivity and Specificity, Cohort Studies, Predictive Value of Tests, medicine.artery, Internal medicine, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, Prospective Studies, Prospective cohort study, Aged, First episode, Echocardiography, Doppler, Pulsed, Ejection fraction, business.industry, Coronary Stenosis, Percutaneous coronary intervention, Middle Aged, medicine.disease, Right ventricular function, Right ventricular infarction, Survival Rate, Stenosis, Right coronary artery, RC666-701, Cardiology, Ventricular Function, Right, Surgery, Female, Original Article, Cardiology and Cardiovascular Medicine, Isovolumic relaxation time, business, Right coronary artery stenosis
Abstract: Background: Presence of right ventricular (RV) infarction imposes a higher risk of adverse events in inferior wall myocardial infarction (IWMI). In this study, we attempted to correlate various indices of RV function assessed by echocardiography with presence of a proximal right coronary artery (RCA) stenosis in patients with first episode of acute IWMI. Methods: In a prospective study, patients with first episode of acute IWMI underwent echocardiographic assessment within 24 h of symptom onset and indices of RV function viz. RV fractional area change (RVFAC), tricuspid annular plane systolic excursion (TAPSE), myocardial performance index (MPI) and tissue Doppler velocities from RV free wall were measured. Patients who underwent coronary angiogram (CAG) within one month and they were classified into group 1 and group 2 based on the presence or absence, respectively, of a significant proximal RCA stenosis. Results: There were 90 patients with first episode of IWMI of which 67 patients underwent CAG. There was significant difference between group 1 (n = 26) and group 2 (n = 41) in TAPSE (13.5 ± 1.3 vs 21.3 ± 1.7, p
Published: 2012

61. Hammock mitral valve: A rare cause of congenital mitral regurgitation – A case report

Author: K T Sajeer, Mangalath Narayanan Krishnan, Chakanalil Govindan Sajeev, Gopalan Nair Rajesh, and Anishkumar Nair
Subjects: Congenital mitral regurgitation, medicine.medical_specialty, RD1-811, Case Report, Congenital, Hammock valve, Internal medicine, Mitral valve, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, cardiovascular diseases, Congenital mitral insufficiency, Papillary muscle, Mitral regurgitation, Heart Failure, Heart Valve Prosthesis Implantation, business.industry, Infant, Newborn, Mitral Valve Insufficiency, medicine.disease, Surgery, medicine.anatomical_structure, Abnormal mitral valve, Echocardiography, RC666-701, Heart failure, cardiovascular system, Cardiology, Mitral Valve, Cardiology and Cardiovascular Medicine, business, Apical systolic murmur
Abstract: Hammock valve, also known as anomalous mitral arcade is a rare mechanism for congenital mitral insufficiency. We report a case of a two-week-old neonate who presented with features of heart failure and an apical systolic murmur. Echocardiogram showed severe mitral regurgitation and abnormal mitral valve with direct attachment of mitral leaflets to papillary muscle without intervening chordae tendinae, typical of hammock valve. Heart failure was controlled with ionotrpes and diuretics. The literature on the hammock mitral valve is reviewed.
Published: 2014
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62. ‘Foetus inside the heart’!! Large rhabdomyomas in the heart of a newborn

Author: Mangalath Narayanan Krishnan, Gopalan Nair Rajesh, and K T Sajeer
Subjects: Fetus, medicine.medical_specialty, Lung, Respiratory distress, business.industry, Day of life, respiratory system, medicine.disease, Systolic murmur, medicine.anatomical_structure, Internal medicine, Heart failure, medicine, Room air distribution, Cardiology, Cardiology and Cardiovascular Medicine, business, Images in Cardiovascular Medicine, Oxygen saturation (medicine)
Abstract: A full-term male newborn presented on the seventh day of life with breathlessness and refusal of feeds for 3 days. The baby was tachypnoeic and had respiratory distress, but was not cyanotic. Oxygen saturation was 90% on room air. On examination, there was a systolic murmur, cardiomegaly and features of heart failure. Chest X-ray showed bilateral lung …
Published: 2013
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63. ‘Continuously regurgitating mitral valve’: systolic and diastolic mitral regurgitation in a case of severe aortic regurgitation and complete heart block

Author: Gopalan Nair Rajesh, Mangalath Narayanan Krishnan, and Deepak Raju
Subjects: Presyncope, Mitral regurgitation, medicine.medical_specialty, Heart block, business.industry, Diastole, Regurgitation (circulation), medicine.disease, Jugular venous pressure, medicine.anatomical_structure, Mitral valve, Internal medicine, Anesthesia, cardiovascular system, medicine, Cardiology, cardiovascular diseases, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Atrioventricular block, Images in Cardiovascular Medicine
Abstract: A 67-year-old man presented with progressive effort dyspnoea and intermittent episodes of presyncope. His pulse was regular at 48/min with collapsing character. His mean jugular venous pressure was normal with intermittent cannon waves. Precordial examination revealed cardiomegaly with forceful apical impulse. On auscultation, a long early diastolic murmur of aortic regurgitation (AR) and a soft systolic murmur …
Published: 2013
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64. Right bundle branch block pattern in right ventricular endocardial pacing: A needless concern?

Author: Mangalath Narayanan Krishnan, Cicy Bastian, Gopalan Nair Rajesh, Peringadan Gopalan Nithin, Vellani Haridasan, M.P. Ranjith, K T Sajeer, and Chakanalil Govindan Sajeev
Subjects: medicine.medical_specialty, RBBB, lcsh:Diseases of the circulatory (Cardiovascular) system, Left bundle branch block, business.industry, Perforation (oil well), LBBB, Right bundle branch block, medicine.disease, Surface electrocardiogram, Permanent pace maker, lcsh:RC666-701, Internal medicine, medicine, Cardiology, right ventricular endocardial pacing, cardiovascular diseases, Permanent pacemaker, business
Abstract: Right ventricular (RV) endocardial pacing in permanent pacemaker implantation usually yields a left bundle branch block (LBBB) pattern in surface electrocardiogram (ECG). The presence of right bundle branch block (RBBB) pattern raises the suspicion of lead perforation. We report a case of RV endocardial permanent pacemaker implantation showing a RBBB pattern in ECG, suggesting a complication. However, further work-up revealed that the lead was appropriately located at the RV apex.
Published: 2013

65. Correlation of pulmonary capillary wedge pressure with left atrial pressure in patients with mitral stenosis before and after balloon mitral valvotomy

Author: Gopalan Nair Rajesh, Dolly Mathew, Uppalakal Bijilesh, Vellani Haridasan, C.G. Sajeev, Cicy Bastion, M.N. Krishnan, Biju George, Desabandhu Vinayakumar, and Kader Muneer
Subjects: medicine.medical_specialty, RD1-811, Balloon mitral valvotomy, business.industry, medicine.disease, Stenosis, Left atrial pressure, RC666-701, Internal medicine, medicine, Cardiology, Diseases of the circulatory (Cardiovascular) system, Surgery, In patient, Cardiology and Cardiovascular Medicine, Pulmonary wedge pressure, business
Published: 2014
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66. Baseline mean platelet volume as a short-term prognostic factor for acute myocardial infarction

Author: Gopalan Nair Rajesh, M.P. Ranjith, Biju George, K.F. Rajesh, C.G. Sajeev, V. Haridasan, and Mangalath Narayanan Krishnan
Subjects: medicine.medical_specialty, Prognostic factor, business.industry, Internal medicine, Cardiology, Medicine, Myocardial infarction, Mean platelet volume, Cardiology and Cardiovascular Medicine, business, medicine.disease, Baseline (configuration management), Term (time)
Published: 2014
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67. Malignant Arrhythmia with Benign Tumour: Fibrolipoma of the Left Ventricle

Author: Kader Muneer, Mangalath Narayanan Krishnan, Vinayakumar Deshabandhu, Anishkumar Nair, Sajeer Kalathingathodika, Kudakkachira Mathew Kuriakose, Chakanalil Govindan Sajeev, Gopalan Nair Rajesh, Gomathy Subramaniam, and Rajesh Sadanandan Pillai
Subjects: Cardiac tumor, medicine.medical_specialty, Cardiac magnetic resonance, Case Report, Asymptomatic, Syncope, Ventricular flutter, Cardiac magnetic resonance imaging, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Sinus rhythm, cardiovascular diseases, Recent onset, Fibrolipoma, medicine.diagnostic_test, business.industry, medicine.disease, medicine.anatomical_structure, Ventricle, cardiovascular system, Cardiology, medicine.symptom, Transthoracic echocardiogram, Cardiology and Cardiovascular Medicine, business
Abstract: We report a case of young male referred for evaluation of recent onset recurrent syncope. Inhospital electrocardiogram revealed an episode of ventricular flutter which reverted spontaneously to sinus rhythm. Transthoracic echocardiogram showed hyperechoic mass in the left ventricle. For further tissue characterization a cardiac magnetic resonance imaging was done which revealed a left ventricular mass with predominant fat content. The tumor was surgically resected. Histopathological examination confirmed the diagnosis of cardiac fibrolipoma. The patient recovered and is currently asymptomatic.
Published: 2014
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68. Aortopulmonary window: a rare mechanism of inter-circulatory mixing and prepared left ventricle in transposition of the great arteries with intact ventricular septum

Author: Gopalan Nair, Rajesh, primary, Kalathingathodika, Sajeer, additional, and Bastian, Cicy, additional
Published: 2013
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69. Prognostic significance of coronary sinus filling time in patients with angina and normal coronaries at one year follow up

Author: Gopalan Nair Rajesh, V. Haridasan, P. Kadermuneer, G.V. Vinod, Biju George, Cicy Bastion, Mangalath Narayanan Krishnan, Dolly Mathew, C.G. Sajeev, and Desabandhu Vinayakumar
Subjects: Male, medicine.medical_specialty, Time Factors, RD1-811, Radiofrequency ablation, Coronary sinus filling time, Chest pain, Coronary Angiography, Asymptomatic, law.invention, Angina Pectoris, Angina, Electrocardiography, law, Risk Factors, Internal medicine, Medicine, Outpatient clinic, Diseases of the circulatory (Cardiovascular) system, Humans, Myocardial infarction, Prospective Studies, Coronary sinus, Supraventricular arrhythmia, business.industry, Coronary Sinus, Middle Aged, medicine.disease, Prognosis, Coronary Vessels, Microvascular dysfunction, RC666-701, Cardiology, Exercise Test, Surgery, Female, Original Article, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Normal coronaries, Follow-Up Studies
Abstract: Background Coronary sinus filling time (CSFT) has been proposed as a simple method for assessment of coronary microvascular function in patients with angina and normal coronaries. But its correlation with inducible ischemia and prognostic significance in predicting future cardiovascular events has not been studied. The present study assessed the prognostic significance of CSFT during one year of follow up. Methods We compared coronary sinus filling time of patients with angina and normal coronaries with that of control population. Control group was formed by those patients with supraventricular arrhythmia undergoing radiofrequency ablation and having normal coronaries. Baseline treadmill test (TMT) parameters like workload, duration and Duke Score were assessed. Patients were followed up for one year and a composite of cardiovascular mortality and non-fatal myocardial infarction was analyzed. Number of patients presenting to emergency or outpatient department with recurrent chest pain symptoms during one year follow up was considered for secondary outcome analysis. Coronary sinus filling time was analyzed with respect to cardiovascular events, repeat hospitalization for recurrent angina and TMT parameters. Results Total 72 patients and 16 controls were studied. Mean CSFT value in the study group was 5.31 ± 1.03 sec and in the control group was 4.16 ± 0.72 sec and the difference was significant ( p value = 0.0001). No correlation was found between baseline and repeat TMT parameters with CSFT. There was no cardiovascular mortality or hospitalization for non-fatal MI during one year follow up. But patients with frequent emergency or outpatient department visits with chest pain had a high CSFT compared with asymptomatic patients ( p value = 0.005). Conclusion Coronary sinus filling time may be used as a simple marker of microvascular dysfunction in patients with angina and normal coronaries. Patients with recurrent chest pain symptoms after one year follow up were found to have high CSFT compared to asymptomatic patients.
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70. Effect of balloon mitral valvotomy on left ventricular function in rheumatic mitral stenosis

Author: P. Kadermuneer, Desabandhu Vinayakumar, Biju George, Vellani Haridasan, Mangalath Narayanan Krishnan, Dolly Mathew, Gopalan Nair Rajesh, Pradeep Sreekumar, C.G. Sajeev, and Cicy Bastian
Subjects: Male, viruses, Rheumatic mitral stenosis, 030204 cardiovascular system & hematology, Ventricular Function, Left, 030218 nuclear medicine & medical imaging, Ventricular Dysfunction, Left, 0302 clinical medicine, Balloon mitral valvotomy, Mitral Valve Stenosis, Postoperative Period, Prospective Studies, Myocardial Performance Index, Prospective cohort study, Ejection fraction, Ventricular function, food and beverages, Atrial fibrillation, Prognosis, Mitral annular plane systolic excursion, Echocardiography, Cardiology, cardiovascular system, Mitral Valve, Original Article, Female, Cardiology and Cardiovascular Medicine, Adult, Balloon Valvuloplasty, medicine.medical_specialty, RD1-811, Longitudinal left ventricular dysfunction, 03 medical and health sciences, Mitral annular systolic velocity, Internal medicine, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, cardiovascular diseases, business.industry, Rheumatic Heart Disease, Stroke Volume, medicine.disease, Stenosis, RC666-701, Surgery, business, Follow-Up Studies
Abstract: Aim Mitral stenosis (MS) is found to produce left ventricular (LV) dysfunction in some studies. We sought to study the left ventricular function in patients with rheumatic MS undergoing balloon mitral valvotomy (BMV). Ours is the first study to analyze effect of BMV on mitral annular plane systolic excursion (MAPSE), and to quantify prevalence of longitudinal left ventricular dysfunction in rheumatic MS. Methods In this prospective cohort study, we included 43 patients with severe rheumatic mitral stenosis undergoing BMV. They were compared to twenty controls whose distribution of age and gender were similar to that of patients. The parameters compared were LV ejection fraction (EF) by modified Simpson's method, mitral annular systolic velocity (MASV), MAPSE, mitral annular early diastolic velocity (E′), and myocardial performance index (MPI). These parameters were reassessed immediately following BMV and after 3 months of procedure. Results MASV, MAPSE, E′, and EF were significantly lower and MPI was higher in mitral stenosis group compared to controls. Impaired longitudinal LV function was present in 77% of study group. MAPSE and EF did not show significant change after BMV while MPI, MASV, and E′ improved significantly. MASV and E′ showed improvement immediately after BMV, while MPI decreased only at 3 months follow-up. Conclusions There were significantly lower mitral annular motion parameters including MAPSE in patients with rheumatic mitral stenosis. Those with atrial fibrillation had higher MPI. Immediately after BMV, there was improvement in LV long axis function with a gradual improvement in global LV function. There was no significant change of MAPSE after BMV.
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71. Prospective study of infective endocarditis in a tertiary care centre in Kerala: Prognostic role of baseline ESR Vs. CRP

Author: Chakanalil Govindan Sajeev, Sandeep Mohanan, Mangalath Narayanan Krishnan, V. Haridasan, and Gopalan Nair Rajesh
Subjects: musculoskeletal diseases, Pediatrics, medicine.medical_specialty, RD1-811, business.industry, medicine.disease, Tertiary care, Infective endocarditis, Internal medicine, RC666-701, medicine, Diseases of the circulatory (Cardiovascular) system, Surgery, Cardiology and Cardiovascular Medicine, Baseline (configuration management), business, Prospective cohort study, skin and connective tissue diseases
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72. C-reactive protein at admission as an independent predictor of major complications, need for urgent surgery and mortality in infective endocarditis patients: A protocol-based prospective analysis

Author: Sandeep Mohanan, Gopalan Nair Rajesh, and Mangalath Narayanan Krishnan
Subjects: Protocol (science), medicine.medical_specialty, biology, RD1-811, business.industry, C-reactive protein, medicine.disease, Independent predictor, Surgery, Prospective analysis, Infective endocarditis, RC666-701, medicine, biology.protein, Diseases of the circulatory (Cardiovascular) system, Major complication, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
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73. Aortopulmonary window: a rare mechanism of inter-circulatory mixing and prepared left ventricle in transposition of the great arteries with intact ventricular septum.

Author: Gopalan Nair, Rajesh, Kalathingathodika, Sajeer, and Bastian, Cicy
Published: 2014
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74. Initial Invasive or Conservative Strategy for Stable Coronary Disease

Author: Maron D. J., Hochman J. S., Reynolds H. R., Bangalore S., O'Brien S. M., Boden W. E., Chaitman B. R., Senior R., Lopez-Sendon J., Alexander K. P., Lopes R. D., Shaw L. J., Berger J. S., Newman J. D., Sidhu M. S., Goodman S. G., Ruzyllo W., Gosselin G., Maggioni A. P., White H. D., Bhargava B., Min J. K., John Mancini G. B., Berman D. S., Picard M. H., Kwong R. Y., Ali Z. A., Mark D. B., Spertus J. A., Krishnan M. N., Elghamaz A., Moorthy N., Hueb W. A., Demkow M., Mavromatis K., Bockeria O., Peteiro J., Miller T. D., Szwed H., Doerr R., Keltai M., Selvanayagam J. B., Gabriel Steg P., Held C., Kohsaka S., Mavromichalis S., Kirby R., Jeffries N. O., Harrell F. E., Rockhold F. W., Broderick S., Bruce Ferguson T., Williams D. O., Harrington R. A., Stone G. W., Rosenberg Y, ISCHEMIA Research Group: Joseph Ricci, A Tello Montoliu, A I Robero Aniorte, Abbey Mulder, Abhay A Laddu, Abhinav Goyal, Abhishek Dubey, Abhishek Goyal, Abigail Knighton, Abraham Oomman, Adam J Jaskowiak, Adam Kolodziej, Adam Witkowski, Adnan Hameed, Adriana Anesini, Afshan Hussain, Agne Juceviciene, Agne Urboniene, Agnes Jakal, Agnieszka Szramowska, Ahmad Khairuddin, Ahmed Abdel-Latif, Ahmed Adel, Ahmed Aljzeeri, Ahmed Kamal, Ahmed Talaat, Aimee Mann, Aira Contreras, Ajit Kumar, V K Kumar, Akemi Furukawa, Akshay Bagai, Akvile Smigelskaite, Alain Furber, Alain Rheault, Alaine Melanie Loehr, Alan Rosen, Albert Varga, Albertina Qelaj, Alberto Barioli, Aldo Russo, Alec Moorman, Alejandro Gisbert, Aleksandra Fratczak, Aleksandras Laucevicius, Alena Kuleshova, Alessandro Sionis, Alexander A Sirker, Alexander M Chernyavskiy, Alexandra Craft, Alexandra Vazquez, Alexandre Ciappina Hueb, Alexandre S Colafranseschi, Alexandre Schaan de Quadros, Alexandre Tognon, Ali Alghamdi, Alice Manica Muller, Aline Nogueira Rabaça, Aline Peixoto Deiro, Alison Hallam, Allegra Stone, Allison Schley, Almudena Castro, Alvaro Rabelo Ales, Amanda Germann, Amanda O'Malley, Amar Uxa, Amarachi Ojajuni, Amarino C Oliveira Jr, Amber B Hull, Ambuj Roy, Amer Zarka, Amir Janmohamed, Ammani Brown, Ammy Malinay, Amparo Martinez Monzonis, Amy J Richards, Amy Iskandrian, Amy Ollinger, Ana D Djordjevic-Dikic, Ana Fernández Martínez, Ana Gomes Almeida, Ana Paula Batista, Ana Rita Francisco, Ana S Mladenovic, Ana Santana, Anam Siddiqui, Anastasia M Kuzmina-Krutetskaya, Andras Vertes, Andre S Sousa, Andre Gabriel, André Schmidt, Andrea M Lundeen, Andrea Bartykowszki, Andrea Lorimer, Andrea Mortara, Andrea Pascual, Andreia Coelho, Andreia Rocha, Andrés García-Rincón, Andrew G Howarth, Andrew J Moriarty, Andrew Docherty, Andrew Starovoytov, Andrew Zurick, Andrzej Łabyk, Andrzej Swiatkowski, Andy Lam, Anelise Kawakami, Angela Hoye, Angela Kim, Angelique Smit, Angelo Nobre, Anil V Shah, Anja Ljubez, Anjali Anand, Ankush Sachdeva, Ann Greenberg, Ann Luyten, Ann Ostrander, Anna Di Donato, Anna Cichocka-Radwan, Anna Fojt, Anna Plachcinska, Anna Proietti, Anna Teresinska, Anne Marie Webb, Anne Cartwright, Anne Heath, Anne Mackin, Anong Amaritakomol, Anong Chaiyasri, Anoop Chauhan, Anoop Mathew, Anthony Gemignani, Anto Luigi Andres, Antonia Vega, Antonietta Hansen, Antonino Ginel Iglesias, Antonio Carlos Carvalho, Antonio Di Chiara, Antonio Serra Peñaranda, Antonio Carvalho, Antonio Colombo, Antonio Fiarresga, Anupama Rao, Aquiles Valdespino-Estrada, Araceli Boan, Areef Ishani, Ariel Diaz, Arijit Ghosh, Arintaya Prommintikul, Arline Roberts, Arnold H Seto, Arnold P Good, Arshed Quyyumi, Arthur J Labovitz, Arthur Kerner, Arturo S Campos-Santaolalla, Arunima Misra, Ashok Mukherjee, Ashok Seth, Ashraf Seedhom, Asim N Cheema, Asker Ahmed, Atul Mathur, Atul Verma, Audrey W Leong, Axel Åkerblom, Axelle Fuentes, Aynun Naher, Badhma Valaiyapathi, Baljeet Kaur, Bandula Guruge, Barbara Brzezińska, Barbara Nardi, Bartosz Czarniak, Bebek Singh, Begoña Igual, Bela Merkely, Belen Cid Alvarez, Benjamin J Spooner, Benjamin J W Chow, Benjamin Cheong, Benoy N Shah, Bernard de Bruyne, Bernardas Valecka, Bernhard Jäger, Beth A Archer, Beth Abramson, Beth Jorgenson, Bethany Harvey, Betsy O'Neal, Bev Atkinson, Bev Bozek, Bevin Lang, Bijulal Sasidharan, Bin Yang, Bin Zhang, Binoy Mannekkattukudy Kurian, Bjoern Goebel, Bob Hu, Bogdan A Popescu, Bogdan Crnokrak, Bolin Zhu, Bonnie J Kirby, Brandi D Zimbelman, Brandy Starks, Branko D Beleslin, Brenda Hart, Brian P Shapiro, Brian McCandless, Brianna Wisniewski, Brigham R Smith, Brooks Mirrer, Bruce McManus, Bruce Rutkin, Bruna Edilena Paulino, Bruna Maria Ascoli, Bryn Smith, Byron J Allen, C Michael Gibson, C Noel Bairey Merz, Calin Pop, Cameron Hague, Camila Thais de Ormundo, Candace Gopaul, Candice P Edillo, Carísi A Polanczyk, Carita Krannila, Carla Vicente, Carl-Éric Gagné, Carlo Briguori, Carlos Peña Gil, Carlos Alvarez, Carly Ohmart, Carmen C Beladan, Carmen Ginghina, Carol M Kartje, Caroline Alsweiler, Caroline Brown, Caroline Callison, Caroline Pinheiro, Caroline Rodgers, Caroline Spindler, Carolyn Corbett, Carrie Drum, Casey Riedberger, Catherine Bone, Catherine Fleming, Catherine Gordon, Catherine Jahrsdorfer, Catherine Lemay, Catherine Weick, Cathrine Patten, Cecilia Goletto, Cezary Kepka, Chandini Suvarna, Chang Xu, Chantale Mercure, Charle A Viljoen, Charlene Wiyarand, Charles Jia-Yin Hou, Charles Y Lui, Charles Cannan, Charles Cornet, Charlotte Pirro, Chataroon Rimsukcharoenchai, Chen Wang, Cheng-Ting Tsai, Chen-Yen Chien, Cheryl A Allardyce, Chester M Hedgepeth, Chetan Patel, Chiara Attanasio, Chih-Hsuan Yen, Chi-Ming Chow, Ching Min Er, Ching-Ching Ong, Cholenahally Nanjappa Manjunath, Chris Beck, Chris Buller, Christel Vassaliere, Christian Hamm, Christiano Caldeira, Christie Ballantyne, Christina Björklund, Christine R Hinton, Christine Bergeron, Christine Masson, Christine Roraff, Christine Shelley, Christophe Laure, Christophe Thuaire, Christopher Kinsey, Christopher McFarren, Christopher Spizzieri, Christopher Travill, Chun-Chieh Liu, Chung-Lieh Hung, Chunguang Li, Chun-Ho Yun, Chunli Xia, Ciarra Heard, Cidney Schultz, Clare Venn-Edmonds, Claudia P Hochberg, Claudia Wegmayr, Claudia Cortés, Claudia Escobar, Cláudia Freixo, Claudio T Mesquita, Clemens T Kadalie, Colin Berry, Constance Philander, Corine Thobois, Costantino Costantini, Courtney Page, Craig Atkinson, Craig Barr, Craig Paterson, Cristina Bare, Cynthia Baumann, Cynthia Burman, Dalisa Espinosa, Damien Collison, Dan Deleanu, Dan Elian, Dan Gao, Dana Oliver, Daniel P Vezina, Daniel O'Rourke, Daniele Komar, Danielle Schade, Darrel P Francis, Dastan Malaev, David A Bull, David E Winchester, David P Faxon, David Booth, David Cohen, David DeMets, David Foo, David Schlichting, David Taggart, David Waters, David Wohns, Davis Vo, Dawid Teodorczyk, Dawn Shelstad, Dawn Turnbull, Dayuan Li, Dean Kereiakes, Deborah O'Neill, Deborah Yip, Debra K Johnson, Debra Dees, Deepak L Bhatt, Deepika Gopal, Deepti Kumar, Deirdre Mattina, Deirdre Murphy, Delano R Small, Delsa K Rose, Dengke Jiang, Denis Carl Phaneuf, Denise Braganza, Denise Fine, Derek Cyr, Desiree Tobin, Diana Cukali, Diana Parra, Diane Camara, Diane Minshall Liu, Diego Adrián Vences, Diego Franca de Cunha, Dimitrios Stournaras, Dipti Patel, Dongze Li, Donna Exley, Dorit Grahl, Dragana Stanojevic, Duarte Cacela, Dwayne S G Conway, E Pinar Bermudez, Eapen Punnoose, Edgar L Tay, Edgar Karanjah, Edoardo Verna, Eduardo Hernandez-Rangel, Edward D Nicol, Edward O McFalls, Edward T Martin, Edyta Kaczmarska, Ekaterina I Lubinskaya, Elena A Demchenko, Elena Refoyo Salicio, Eli Feen, Elihú Durán-Cortés, Elisabeth M Janzen, Elise L Hannemann, Elise van Dongen, Elissa Restelli Piloto, Eliza Kaplan, Elizabeta Srbinovska Kostovska, Elizabeth Capasso-Gulve, Elizabeth Congdon, Elizabeth Ferguson, Elizaveta V Zbyshevskaya, Ellen Magedanz, Ellie Fridell, Ellis W Lader, Elvin Kedhi, Emanuela Racca, Emilie Tachot, Emily DeRosa, Encarnación Alonso-Álvarez, Eric Nicollet, Eric Peterson, Erick Alexánderson Rosas, Erick Donato Morales, Erin Orvis, Ermina Moga, Estelle Montpetit, Estevao Figueiredo, Eugene Passamani, Eugenia Nikolsky, Eunice Yeoh, Evgeniy I Kretov, Ewa Szczerba, Ewelina Wojtala, Expedito Eustáquio Ribeiro Silva, F Marin Ortuño, Fabio R Farias, Fabio Fimiani, Fabrizio Rolfo, Fa-Chang Yu, Fadi Hage, Fadi Matar, Fahim Haider Jafary, Fang Feng, Fang Liu, Fatima Ranjbaran, Fatima Rodriguez, Fausto J Pinto, Fauzia Rashid, Federica Ramani, Fei Wang, Fernanda Igansi, Filipa Silva, Filippo Ottani, Fiona Haines, Firas Al Solaiman, Flávia Egydio, Flavio Lyra, Florian Egger, Fran Farquharson, Frances Laube, Francesc Carreras Costa, Francesca de Micco, Francesca Bianchini, Francesca Pezzetta, Francesca Pietrucci, Francesco Orso, Francesco Pisano, Francis Burt, Francisca Patuleia Figueiras, Francisco Fernandez-Aviles, Francois Pierre Mongeon, Frans Van de Werf, Franziska Guenther, Fraser N Witherow, Fred Mohr, Frederico Dall'Orto, Fumiyuki Otsuka, G De La Morena, G Karthikeyan, Gabor Dekany, Gabor Kerecsen, Gabriel Galeote, Gabriel Grossmann, Gabriel Vorobiof, Gabriela Sanchez de Souza, Gabriela Guzman, Gabriela Zeballos, Gabriele Gabrielli, Gabriele Jakl-Kotauschek, Gail A Shammas, Gail Brandt, Gang Chen, Gary E Lane, Gary J Luckasen, Gautam Sharma, Gelmina Mikolaitiene, Gennie Yee, Georg Nickenig, George E Revtyak, George J Juang, Gerald Fletcher, Gerald Leonard, Gerard Patrick Devlin, Gerard Esposito, Gergely Ágoston, Gervasio Lamas, Geza Fontos, Ghada Mikhail, Gia Cobb, Gian Piero Perna, Gianpiero Leone, Giles Roditi, Gilles Barone-Rochette, Girish Mishra, Giuseppe Tarantini, Glenda Wong, Glenn S Hamroff, Glenn Rayos, Gong Cheng, Gonzalo Barge-Caballero, Goran Davidović, Goran Stankovic, Gordana Stevanovic, Grace Jingyan Wang, Grace M Young, Graceanne Wayser, Graciela Scaro, Graham S Hillis, Graham Wong, Grazyna Anna Szulczyk, Gregor Simonis, Gregory Kumkumian, Gretchen Ann Peichel, Grzegorz Gajos, Gudrun Steinmaurer, Guilherme G Rucatti, Guilherme Portugal, Guilhermina Cantinho Lopes, Guillem Pons Lladó, Gunnar Frostfelt, Gurpreet S Wander, Gurpreet Gulati, Gustavo Pucci, Hafidz Abd Hadi, Haibo Zhang, Haitao Wang, Halina Marciniak, Han Chen, Hanan Kerr, Hani Najm, Hanna Douglas, Hannah Phillips, Hao Dai, Haojian Dong, Haqeel Jamil, Harikrishnan Sivadasanpillai, Harry Suryapranata, Hassan Reda, Hayley Pomeroy, Heather Barrentine, Heather Golden, Heather Hurlburt, Heidi Wilson, Helen C Tucker, Helene Abergel, Hemalata Siddaram, Hermine Osseni, Herwig Schuchlenz, Hesong Zeng, Hicham Skali, Hilda Solomon, Hollie Horton, Holly Hetrick, Holly Little, Holly Park, Hongjie Chi, Hossam Mahrous, Howard A Levite, Hristo Pejkov, Huajun Li, Hugo Bloise-Adames, Hugo Marques, Hui Zhong, Hui-Min Zhang, Humayrah Hashim, Hung-I Yeh, Hussien El Fishawy, Ian Webb, Iftikhar Kullo, Igor O Grazhdankin, Ihab Hamzeh, Ikraam Hassan, Ikuko Ueda, Ileana L Pina, Ilona Tamasauskiene, Ilse Bouwhuis, Imran Arif, Ina Wenzelburger, Inês Zimbarra Cabrita, Ines Rodrigues, Inga H Robbins, Inga Soveri, Ingela Schnittger, Iqbal Karimullah, Ira M Dauber, Iram Rehman, Irena Peovska Mitevska, Irene Marthe Lang, Irina Subbotina, Irma Kalibataite-Rutkauskiene, Irni Yusnida, Isabel Estela Carvajal, Isabella C Palazzo, Isabelle Hogan, Isabelle Roy, Ishba Syed, Ishita Tejani, Ivan A Naryshkin, Ivana Jankovic, Iwona Niedzwiecka, J David Knight, Jacek Kusmierek, Jackie M White, Jackie Chow, Jacob Udell, Jacqueline E Tamis-Holland, Jacqueline Fannon, Jacquelyn A Quin, Jacquelyn Do, Jaekyeong Heo, Jakub Maksym, James E Davies, James H O'Keefe Jr, James J Jang, James Cha, James Harrison, James Hirsch, James Stafford, James Tatoulis, Jamie Rankin, Jan Henzel, Jan Orga, Jana Tancredi, Janaina Oliveira, Jane Burton, Jane Eckstein, Jane Marucci, Janet P Knight, Janet Blount, Janet Halliday, Janetta Kourzenkova, Janitha Raj, Jan-Malte Sinning, Jaqueline Pozzibon, Jaroslaw Drozdz, Jaroslaw Karwowski, Jason D Glover, Jason Loh Kwok, Jason T Call, Jason Linefsky, Jassira Gomes, Jati Anumpa, Javier J Garcia, Javier Courtis, Jay Meisner, K Jayakumar, Jayne Scales, Jean E Denaro, Jean Michel Juliard, Jean Ho, Jeanette K Stansborough, Jean-Michel Juliard, Jeanne Russo, Jeannette J M Schoep, Jeet Thambyrajah, Jeff Leimberger, Jeffery A Breall, Jeffrey A Kohn, Jeffrey C Milliken, Jeffrey Anderson, Jeffrey Blume, Jeffrey Kanters, Jeffrey Lorin, Jeffrey Moses, Jelena J Stepanovic, Jelena Celutkiene, Jelena Djokic, Jelena Stojkovic, Jenne M Jose, Jenne Manchery, Jennifer A Mull, Jennifer H Czerniak, Jennifer L Stanford, Jennifer Gillis, Jennifer Horst, Jennifer Isaacs, Jennifer Langdon, Jennifer Thomson, Jennifer Tomfohr, Jennifer White, Jen-Yuan Kuo, Jeremy Rautureau, Jerome Fleg, Jessica Berg, Jessica Rodriguez, Jessica Waldron, Jhina Patro, Jia Li, Jiajia Mao, Jiamin Liu, Jian'an Wang, Jianhua Li, Jianxin Zhang, Jie Qi, Jihyun Lyo, Jill Marcus, Jim Blankenship, Jing Zhang, Jingjing Liu, Jing-Yao Fan, Jiun-Yi Li, Jiwan Pradhan, Jiyan Chen, J M Rivera Caravaca, Jo Evans, Joan Garcia Picart, Joan Hecht, Joanna Jaroch, Joanna Zalewska, Joanne Kelly, Joanne Taaffe, João Reynaldo Abbud, João V Vitola, Joaquín V Peñafiel, Jocelyne Benatar, Jody Bindeman, Joe Sabik, Joel Klitch, Johann Christopher, Johannes Aspberg, John D Friedman, John F Beltrame, John F Heitner, John Joseph Graham, John R Davies, John Doan, John Kotter, John Kurian, John Mukai, John Pownall, Jolanta Sobolewska, Jon Kobashigawa, Jonathan L Goldberg, Jonathan W Bazeley, Jonathan Byrne, Jonathan Himmelfarb, Jonathan Leipsic, Jonean Thorsen, Jorge F Trejo Gutierrez, Jorge Escobedo, Jorik Timmer, José A Ortega-Ramírez, José Antonio Marin-Neto, Jose D Salas, Jose Enrique Castillo, Jose Francisco Saraiva, José J Cuenca-Castillo, Jose L Diez, José Luis Narro Villanueva, José Luiz da Vieira, José M Flores-Palacios, Jose Ramon Gonzalez, Jose Seijas Amigo, Jose Fragata, Josep Maria Padró, Josheph F X McGarvey Jr, Joseph Hannan, Joseph Sacco, Joseph Sweeny, Joseph Wiesel, Josephine D Abraham, Joshua P Loh, Joy Burkhardt, Joyce R White, Joyce Riestenberg-Smith, Judit Sebo, Judith L Meadows, Judith Wright, Judy Mae Foltz, Judy Hung, Judy Otis, Juergen Stumpf, Jui-Peng Tsai, Julia S Dionne, Julia de Aveiro Morata, Julie Bunke, Julie Morrow, Julio César Figal, Jun Fujita, Jun Jiang, Junhua Li, Junqing Yang, Juntima Euathrongchit, Jyotsna Garg, K Manjula Rani, K Preethi, Kaatje Goetschalckx, Kai Eggers, Kamalakar Surineni, Kanae Hirase, T R Kapilamoorthy, Karen Calfas, Karen Gratrix, Karen Hallett, Karen Hultberg, Karen Nugent, Karen Petrosyan, Karen Swan, Karolina Kryczka, Karolina Wojtczak-Soska, Karolina Wojtera, Karsten Lenk, Karthik Ramasamy, Katarzyna Łuczak, Katarzyna Malinowska, Kate Pointon, Kate Robb, Katherine Martin, Kathleen Claes, Kathryn Carruthers, Kathy E Siegel, Katia Drouin, Katie Fowler-Lehman, Kavita Rawat, Kay Rowe, Keiichi Fukuda, Keith A A Fox, Ken Mahaffey, Kendra Unterbrink, Kenneth Giedd, Kerrie Van Loo, Kerry Lee, Kerstin Bonin, Kevin R Bainey, Kevin T Harley, Kevin Anstrom, Kevin Chan, Kevin Croce, Kevin Landolfo, Kevin Marzo, Keyur Patel, Khaled Abdul-Nour, Khaled Alfakih, Khaled Dajani, Khaled Ziada, Khaula Baloch, Khrystyna Kushniriuk, Kian-Keong Poh, Kim F Ireland, Kim Holland, Kimberly Ann Byrne, Kimberly E Halverson, Kimberly Elmore, Kimberly Miller-Cox, Kiran Reddy, Kirsten J Quiles, Kirsty Abercrombie, Klaus Matschke, Konrad Szymczyk, Koo Hui Chan, Kotiboinna Preethi, Kozhaya Sokhon, Krissada Meemuk, Kristian Thygesen, Kristin M Salmi, Kristin Newby, Kristina Wippler, Kristine Arges, Kristine Teoh, Krystal Etherington, Krystyna Łoboz-Grudzień, Krzysztof W Reczuch, Krzysztof Bury, Krzysztof Drzymalski, Krzysztof Kukuła, Kuo-Tzu Sung, Kurt Huber, Ladda Douangvila, Lance Sullenberger, Larissa Miranda Trama, Laszlone Matics, Laura Drew, Laura Flint, Laura Keinaite, Laura Sarti, Laurel Kolakaluri, Lawrence M Phillips, Lawrence Friedman, Lawrence Phillips, Lazar Velicki, Leah Howell, Leandro C Maranan, Leanne Cox, Ledjalem Daba, Lei Zhang, Lekshmi Dharmarajan, Leo Bockeria, Leonardo Pizzol Caetano, Leonardo Bridi, Leonid L Bershtein, Leszek Sokalski, Li Hai Yan, Li Li, Lia Nijmeijer, Lidia Sousa, Lihong Xu, Lihua Zhang, Lili Zhang, Lilia Schiavi, Lilian Mazza Barbosa, Lillian L Khor, Lina Felix-Stern, Linda L Hall, Linda M Hollenweger, Linda Arcand, Linda Davidson-Ray, Linda Schwarz, Lindsey N Sikora, Lingping Chi, Lino Patricio, Liping Zhang, Lisa Chaytor, Lisa Hatch, Lisa McCloy, Lisa Wong, Liselotte Persson, Lixin Jiang, Liz Low, Ljiljana Pupic, Loïc Bière, Lorenzo Monti, Lori Christensen, Lori Pritchard, Loriane Black, Lori-Ann Desimone, Lori-Ann Larmand, Lorraine McGregor, Louise Morby, Louise Thomson, Luc Harvey, Luciana de Pádua Baptista, Lucilla Garcia, Ludivine Eliahou, Ludmila Helmer, Luis F Smidt, Luis Bernanrdes, Luis Guzman, Luiz A Carvalho, Luyang Xiong, Lynette L Teo, Lynn M Neeson, Lynne Winstanley, M Barbara Srichai-Parsia, M Quintana Giner, M Sowjanya Reddy, M Valdés Chávarri, M Grazia Rossi, Maarten Simoons, Maayan Konigstein, Maciej Lesiak, Maciej Olsowka, Mafalda Selas, Magalie Corfias, Magdalena Madero Rovalo, Magdalena Łanocha, Magdalena Miller, Magdalena Misztal-Teodorczyk, Magdalena Rantinella, Magdy Abdelhamid, Magnolia Jimenez, Mahboob Alam, Mahevamma Mylarappa, Mahfouz El Shahawy, Mahmoud Mohamed, Mahmud Al-Bustami, Majo X Joseph, Malgorzata Frach, Małgorzta Celińska-Spodar, Malte Helm, Manas Chacko, Mandy Murphy, Manitha Vinod, Manjula Rani, Manu Dhawan, Manuela Mombelli, Marcel Weber, Marcello Galvani, Marcelo Jamus Rodrigues, Marcia F Dubin, Marcia F Werner Bayer, Marcin Szkopiak, Marco Antonio Monsalve, Marco Bizzaro Santos, Marco Magnoni, Marco Marini, Marco Sicuro, Marco Zenati, Marcos Valério Coimbra Resende, Marek Roik, Margalit Bentzvi, Margaret Gilsenan, Margaret Iraola, Margot C Quinn, Maria A Alfonso, Maria Antonieta Pereira Moraes, María Dolores Martínez-Ruíz, María Fernanda Canales, Maria Inês Caetano, Maria P Corral, Maria Pérez García, Maria Victoria Actis, Maria Aguirre, Maria Andreasson, Maria Aprile, Maria Colton, Maria Eugenia Martin, Maria Lasala, Maria Lorenzo, Maria Posada, Maria Shier, Maria Thottam, Mariana V Furtado, Mariana Yumi Okada, Marianna D A Dracoulakis, Marianne De Andrade, Mariano Rubio, Marie Essermark, Marielle Scherrer-Crosbie, Marija T Petrovic, Marija Zdravkovic, Marilyn Black, Marina Garcia, Mario J Garcia, Mariola Szulik, Marisa Orgera, Mark A de Belder, Mark Harbinson, Mark Hyun, Mark Peterson, Mark Xavier, Marlowe Mosley, Marta Capinha, Marta Marcinkiewicz-Siemion, Marta Swiderek, Martha Meyer, Martina Ceseri, Martina Tricoli, Marvin Kronenberg, Mary Williams, Mary Ann Champagne, Mary Colleen Rogge, Mary R Soltau, Mary Streif, Massimo Villella, Massoud Leesar, Matei Claudia, Mateusz Solecki, Matías Nicolás Mungo, Matthew Wall Jr, Matthew Budoff, Matthew Jezior, Matthew Luckie, Matthias Friedrich, Mauren P Haeffner, Maximilian Tscharre, Max-Paul Winter, Mayana Almeida, Mayil S Krishnam, Mayuri Patel, Meenakshi Mishra, Megan Manocchia, Meghana Kakade, Melanie J Munro, Melissa D Chaplin, Melissa LeFevre, Mervyn Andiapen, Michael A Gibson, Michael B Rubens, Michael C Turner, Michael D Shapiro, Michael W Lee, Michael Berlowitz, Michael Davidson, Michael Mack, Michael McDaniel, Michael Mumma, Michal Wlodarczyk, Michel G Khouri, Michel S Slama, Michele Rawlins, Michelle M Bonner, Michelle M Seib, Michelle Chang, Michelle Crowder, Michelle Dixon, Michelle Mayon, Michelle McEvoy, Michelle Yee, Miguel M Fernandes, Miguel Nobre Menezes, Miguel Souto Bayarri, Miguel Barrero, Mikhail T Torosoff, Milan R Dobric, Milan Dobric, Milica Nikola Dekleva, Milind Avdhoot Gadkari, Millie Gomez, Min Tun Kyaw, Miriam Brooks, Miroslav Stevo Martinovic, Mitchel B Lustre, Mohammad Tariq Vakani, Mohammad El-Hajjar, Mohammed Al-Amoodi, Mohammed Hussain, Mohammed Saleem, Moisés Blanco-Calvo, Moisés Jiménez-Santos, Mona Bhatia, Monica Rosca, Monika Laukyte, Montserrat Gracida Blanca, Montserrat Vila Perales, Mouaz H Al-Mallah, Moysés de Oliveira Filho, Mpiko Ntsekhe, Muhamed Saric, Mulei Chen, Myriam Brousseau, Myrthes Emy Takiuti, Nada Cemerlic-Adjic, Nadia Asif, Nadia Gakou, Nafisa Hussain, Nana O Katamadze, Nancy L Clapp, Nancy Aedy, Nandita Nataraj, Nanette K Wenger, Naomi Uchida, Nasrul Ismail, Natalia S Oliveira, Natalia de Carvalho Maffei, Natalie Spitzer, Natasha C Putnam, Naved Aslam, Neamat Mowafy, Neeraj Pandit, Neeraj Parakh, Nevena Garcevic, Ngaire Meadows, Nhi N Tran, Nicholas Danchin, Nicki Lakeman, Nicola Johnston, Nicolas W Shammas, Nicole Saint Vrestil, Nicole Deming, Nier Zhong, Niket Patel, Nikola N Boskovic, Nikolaos Karogiannis, Nikos Werner, Nina Johnston, Ning Zhang, Ning Zhou, Niree Hindoyan, Nirmal Kumar, Nitika Chadha, Nitish Naik, Nodira Aripova, Noloyiso Mtana, Nona A Eskelson, Noor Syamira Mokhtar, Noppon Taksaudom, Nor Asiah Basri, Nora Marchelletta, Norma Hogg, Nungshi Jungla, Nuno Ferreira, Oksana A Lubyanaya, Olga B Nikolaeva, Olga Cañavate, Olga Sobrino, Olga Walesiak, Olga Walter, Olga Zdończyk, Olivia J Lim, Olivia Anaya, Olivia Mancilla, Olivier Dubourg, Olugbenga Bello, Omar Almousalli, Omar Thompson, Oni Olurinde, Or Harel, Osama Raheem, Oscar Méndiz, Óscar Prada-Delgado, Oz Shapira, P Christian Schulze, Pachara Panpunuan, Pal Maurovich-Horvat, Pallav Garg, Paloma Moraga, Pam Singh, Pamela Julian, Pamela Ouyang, Pamela Sigel, Pamela Woodard, Panpan Zhou, Paola Emanuela Poggio, Paola Smanio, Paolo Calabro, Paramjit Jeetley, Pascal Goube, Patricia K Nguyen, Patricia Alarie, Patricia Arakelian, Patricia Arsenault, Patricia Blaise, Patricia Brito, Patricia Cowper, Patricia Endsley, Patricia Mieses, Patrick B Alexander, Patrick Donnelly, Patrick Wilmot, Patrycja Lebioda, Paul C Gordon, Paul Der Mesropian, Paul Galiwango, Paul Hauptman, Paul Kennedy, Paula Beardsley, Paula García-González, Paulo Cury Rezende, Paulo Ricardo Caramori, Pavel S Kozlov, Pedro Canas Silva, Pedro Gabriel Melo Barros E Silva, Pedro Píccaro de Oliveira, Pedro Carvalho, Pedro Modas, Pedro Rio, Peeyush Jain, Peiyu He, Peter A McCullough, Peter H Stone, Peter M Pollak, Peter Douglass, Peter Henriksen, Peter OKane, Peter Ong, Philip Jones, Philip Rogal, Philippe Généreux, Philippe Menasche, Philippe Rheault, Phoebe Goold, Pierre Gervais, Pierre Michaud, Pilar Calvillo, Ping Chai, Piotr Jakubowski, Piotr Pruszczyk, Piotr Slomka, Piyamitr Sritara, Poay-Huan Loh, Poonam Sonawane, Pouneh Samadi, Pragnesh P Parikh, Prakash Deedwania, Pranav M Patel, Praneeth Polamuri, Pratiksha Sharma, Precilia Vasquez, Preeti Kamath, Prince Thomas, Priyadarshani Arambam, Puja K Mehta, Purvez Grant, Pushpa Naik, Qi Zhong, Qian Zhao, Qiang Zhou, Qianqian Yuan, Qin Yu, Qingxian Li, Qiulan Xie, Qiutang Zeng, R J Vindhya, R James Gerlach, Rachel King, Rada Vučić, Radmila Lyubarova, Radoslaw Pracon, 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Stephanie M Lane, Stephanie Ferket, Stephanie Kelly, Stephanie Wasmiller, Stephen H McKellar, Stephen P Hoole, Stephen Fremes, Stephen Preston, Steve Leung, Steven A Fein, Steven J Lindsay, Steven P Sedlis, Steven Giovannone, Steven Michael, Steven Weitz, Stijn van Vugt, Subhash Banerjee, Sudhir Naik, Suellen Hosino, Sukie Desire, Sukit Yamwong, Suku T Thambar, Sulagna Mookherjee, Suman Singh, Sundeep Mishra, Sunil Kumar Verma, Supap Kulthawong, Supatchara Khwakhong, Surendra Naik, Suresh Babu, Surin Woragidpoonpol, Suryaprakash Narayanappa, Susan Derbyshire, Susan Gent, Susan Mathus, Susan Milbrandt, Susan Moore, Susan Regan, Susan Stinson, Susan Webber, Susana Silva, Susanna Stevens, Susanne Gruensfelder, Suthara Aramcharoen, Suvarna Kolhe, Suzana Tavares, Suzanne Arnold, Suzanne Welsh, Svetlana Apostolovic, Swapna Kunhunny, Ta-Chuan Hung, Taissa Zappernick, Tali Sharir, Talita Silva, Tamara Colaiácovo Soares, Tapan Umesh Pillay, Tarun K Mittal, Tatiana Trifonova, Tauane Bello Duarte, Tauqir Huk, Téodora Dutoiu, Terrance Chua, Terry Weyand, Thabitha Charles, Theodoros Kofidis, Theresa McCreary, Thierry Lefevre, Thippeekaa Arumairajah, Thitipong Tepsuwan, Thomas J Mulhearn, Thomas M Meyer, Thomas P Rocco, Thomas R Downes, Thomas Crain, Thomas Haldis, Thomas Mathew, Thomas Redick, Thounaojam Indira Devi, Thuraia Nageh, Tia Cauthren, Tiago Silva, Tiffany Little, Tijana Andric, Tina Harding, Titus Lau, Tiziana Formisano, Tiziano Moccetti, Tomasz Ciurus, Tomasz Mazurek, Tomasz Tarchalski, Toshiyuki Nagai, Tri Tran, Tricia Youn, Trish Tucker, Trudie Milner, Tuhina Bose, Tushar Kotecha, Udo Sechtem, Uma S Valeti, Umberto Cucchini, Umesh Badami, Upendra Kaul, V K Bahl, V S Narain, Valentina Casali, Valeria Godoy, Valerie Robesyn, Vamshi P Priya, Vandana Yadav, Vera McKinney, Veronica De Lenges, Veronica Tinnirello, Vicente Miro, Victor Navarro, Victoria Gumerova, Victoria Hernandez, Vidya Seeratan, Vijay Kumar, Vikentiy Y Kozulin, Viktoria Bulkley, Vilmar Veiga Jr, Vincent Setang, C P Vineeth, Virginai Pubull Nuñez, Virginia Fernández-Figares, Vitor Gomes, Viviana Gabriel, Viviane Dos Santos, Viviane Almeida, Vlad A Iliescu, Vladan Mudrenovic, Vladimir Dzavik, Vojislav L Giga, Walter Enrique Mogrovejo, Wan Xian Chan, Wanda C Marfori, Wanda Parker, Warangkana Mekara, Wassim Nona, Wayne Old, Wayne Pennachi, Weerachai Nawarawong, Wei Chen, Wei Su, Weibing Xing, Wei-Ren Lan, Wenda Crawford, Wendy L Stewart, Wendy Drewes, Wenhua Lin, William B Abernethy, William D Salerno, William F Fearon, William Vergoni, William Weintraub, Winnie C Sia, Wlodzimierz J Musial, Xacobe Flores-Ríos, Xavier Garcia-Moll Marimon, Xi Su, Xiang Ma, Xiangqiong Gu, Xiao Wang, Xiaomei Li, Xiaowei Yao, Xin Fu, Xin Su, Xin Zeng, Xinchun Yang, Xiuhong Li, Xuehua Fang, Xutong Wang, Yaming Geng, Yan Yan, Yanek Pépin-Dubois, Yanfu Wang, Yang Wang, Yanmeng Tian, Yaping Huang, Yechen Han, Yesenia Zambrano, Yi-Hsuan Yang, Ying Tung Sia, Yining Yang, Yitong Ma, Yolayfi Peralta, Yongjian Wu, Yu Kunwu, Yu Zhao, Yudong Peng, Yueh-Hung Lin, Yulan Zhao, Yumei Dong, Yunhai Zhao, Yutthaphan Wannasopha, Yvonne Taul, Zakir Sahul, Zalina Kudzoeva, Zbigniew Kalarus, Zeljko Z Markovic, Zhen Huang, Zheng Ji, Zhenyu Liu, Zhou Yue, Zhulin Zhang, Zhuxi Li, Zile Singh Meharwal, Ziliang Bai, Zixiang Yu, Zohra Huda, Zoltan Davidovits
Subjects: Male, Cardiac Catheterization, Computed Tomography Angiography, medicine.medical_treatment, Myocardial Ischemia, Coronary Disease, Coronary Artery Disease, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Coronary Angiography, ISCHEMIA Research Group, law.invention, Angina, Coronary artery disease, 0302 clinical medicine, Randomized controlled trial, law, Cardiovascular Disease, Myocardial Revascularization, 030212 general & internal medicine, Coronary Artery Bypass, 11 Medical and Health Sciences, Cardiac catheterization, General Medicine, Middle Aged, humanities, Cardiovascular Diseases, Cardiology, Female, Human, medicine.medical_specialty, Ischemia, Article, 03 medical and health sciences, Geriatric cardiology, Percutaneous Coronary Intervention, General & Internal Medicine, Internal medicine, medicine, Humans, Angina, Unstable, Aged, business.industry, Coronary Artery Bypa, Percutaneous coronary intervention, Bayes Theorem, medicine.disease, Heart failure, Quality of Life, business
Abstract: BACKGROUND: Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS: We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS: Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, -1.8 percentage points; 95% CI, -4.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS: Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used. (Funded by the National Heart, Lung, and Blood Institute and others; ISCHEMIA ClinicalTrials.gov number, NCT01471522.).
Published: 2020
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74 results on '"Gopalan Nair Rajesh"'

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