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56. Factors influencing plasma transfusion practices in paediatric intensive care units around the world

Author

Karam, O., Demaret, P., Duhamel, A., Shefler, A., Spinella, P. C., Tucci, M., Leteurtre, S., Stanworth, S. J., Butt, Warwick, Elope, Carmel, Bain, Kym, Erickson, Simon, Smalley, Nathan, Dorofaeff, Tavey, Long, Debbie, Smalley, Nathan, Wiseman, Greg, de Cléty, Stéphan Clément, Berghe, Caroline, de Jaeger, Annick, Trippaerts, Marc, Willems, Ariane, Rooze, Shancy, De Dooy, Jozef, Gilfoyle, Elaine, Wohlgemuth, Lynette, Dumitrascu, Mariana, Withington, Davinia, Hickey, Julia, Choong, Karen, Sanders, Lois, Morrison, Gavin, Tijssen, Janice, Wensley, David, Krahn, Gordon, Dugas, MarcAndre, Gosselin, Louise, Santschi, Miriam, Von Dessauer, Bettina, Ordenes, Nadia, Afshari, Arash, Andersen, Lasse Hoegh, Nilsson, Jens Christian, Johansen, Mathias, Jensen, AnneMette Baek, Mino, Santiago Campos, Grunauer, Michelle, Joram, Nicolas, RoulletRenoleau, Nicolas, Javouhey, Etienne, CourAndlauer, Fleur, Portefaix, Aurélie, Brissaud, Olivier, Guichoux, Julie, Payen, Valérie, Léger, PierreLouis, Afanetti, Mickael, Mortamet, Guillaume, Maria, Matthieu, Breining, Audrey, Tissieres, Pierre, Dorkenoo, Aimée, Deho, Anna, Steinherr, Harry, Nikolaou, Filippia, Camporesi, Anna, Mario, Federica, Kawasaki, Tatsuya, Miura, Shinya, Beca, John, Rea, Miriam, Sherring, Claire, Bushell, Tracey, Bentsen, Gunnar, Dinis, Alexandra, Pereira, Gabriela, Vieira, Marisa, Moniz, Marta, Alshehri, Saleh, Alasnag, Manal, Rajab, Ahmad, Pisarcikova, Maria, Jordan, Iolanda, Balcells, Joan, PerezFerrer, Antonio, de Vicente Sánchez, Jesús, Moyano, Marta Vazquez, Martinez, Antonio Morales, LopezHerce, Jesus, Solana, Maria Jose, González, Jose Carlos Flores, Alonso, Maria Teresa, Faza, Manuel Nieto, Perez, MarieHélène, Amiet, Vivianne, Doell, Carsten, Bordessoule, Alice, Otter, Suzan Cochiusden, Kapitein, Berber, Kneyber, Martin, Brierley, Joe, Rea, Vanessa, McKeever, Stephen, Kelleher, Andrea, Scholefield, Barney, Top, Anke, Kelly, Nicola, Virdee, Satnam, Davis, Peter, George, Susan, Hawkins, Kay C, McCall, Katie, Brown, Victoria, Sykes, Kim, Levin, Richard, MacLeod, Isobel, Horan, Marie, Jirasek, Petr, Inwald, David, Abdulla, Amina, Raghunanan, Sophie, Sparkes, Hannah, Hanson, Sheila, Woods, Katherine, Triscari, David, Murkowski, Kathy, Ozment, Caroline, Steiner, Marie, Nerheim, Dan, Galster, Amanda, Higgerson, Renee, Christie, LeeAnn, Martin, Daniel, Rourke, Liz, Muszynski, Jennifer, Steele, Lisa, Ajizian, Samuel, McCrory, Michael C, OʼBrien, Kevin, Babbitt, Christopher, Felkel, Erin, Levine, Glenn, Truemper, Edward J, Zink, Machelle, Nellis, Marianne, Thomas, Neal J, Spear, Debbie, Markovitz, Barry, Terry, Jeff, Morzov, Rica, Montgomery, Vicki, Michael, Andrew, Thomas, Melissa, Singleton, Marcy, Jarvis, Dean, Nett, Sholeen, Willson, Douglas, Hoot, Michelle, Bembea, Melania, Yiu, Alvin, McKinley, David, Scarlett, Elizabeth, Sankey, Jennifer, Parikh, Minal, Faustino, E. Vincent S., Michelson, Kelly, Rilinger, Jay, Campbell, Laura, Gertz, Shira, Cholette, Jill M., Jeyapalan, Asumthia, Parker, Margaret, Bateman, Scot, and Johnson, Amanda

Published
2017
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58. Noninferiority Margin Size and Acceptance of Trial Results: Contingent Valuation Survey of Clinician Preferences for Noninferior Mortality

Author

Pong, Sandra, primary, Fowler, Robert A., additional, Mitsakakis, Nicholas, additional, Murthy, Srinivas, additional, Pernica, Jeffrey M., additional, Gilfoyle, Elaine, additional, Bowen, Asha, additional, Fontela, Patricia, additional, Seto, Winnie, additional, Science, Michelle, additional, Hutchison, James S., additional, Jouvet, Philippe, additional, Rishu, Asgar, additional, and Daneman, Nick, additional

Published
2022
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59. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group

Author

Wyckoff, Myra H., primary, Singletary, Eunice M., additional, Soar, Jasmeet, additional, Olasveengen, Theresa M., additional, Greif, Robert, additional, Liley, Helen G., additional, Zideman, David, additional, Bhanji, Farhan, additional, Andersen, Lars W., additional, Avis, Suzanne R., additional, Aziz, Khalid, additional, Bendall, Jason C., additional, Berry, David C., additional, Borra, Vere, additional, Böttiger, Bernd W., additional, Bradley, Richard, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Carlson, Jestin N., additional, Cassan, Pascal, additional, Castrén, Maaret, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Cheng, Adam, additional, Chung, Sung Phil, additional, Considine, Julie, additional, Costa-Nobre, Daniela T., additional, Couper, Keith, additional, Dainty, Katie N., additional, Davis, Peter G., additional, de Almeida, Maria Fernanda, additional, de Caen, Allan R., additional, de Paiva, Edison F., additional, Deakin, Charles D., additional, Djärv, Therese, additional, Douma, Matthew J., additional, Drennan, Ian R., additional, Duff, Jonathan P., additional, Eastwood, Kathryn J., additional, El-Naggar, Walid, additional, Epstein, Jonathan L., additional, Escalante, Raffo, additional, Fabres, Jorge G., additional, Fawke, Joe, additional, Finn, Judith C., additional, Foglia, Elizabeth E., additional, Folke, Fredrik, additional, Freeman, Karoline, additional, Gilfoyle, Elaine, additional, Goolsby, Craig A., additional, Grove, Amy, additional, Guinsburg, Ruth, additional, Hatanaka, Tetsuo, additional, Hazinski, Mary Fran, additional, Heriot, George S., additional, Hirsch, Karen G., additional, Holmberg, Mathias J., additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Hung, Kevin K.C., additional, Hsu, Cindy H., additional, Ikeyama, Takanari, additional, Isayama, Tetsuya, additional, Kapadia, Vishal S., additional, Kawakami, Mandira Daripa, additional, Kim, Han-Suk, additional, Kloeck, David A., additional, Kudenchuk, Peter J., additional, Lagina, Anthony T., additional, Lauridsen, Kasper G., additional, Lavonas, Eric J., additional, Lockey, Andrew S., additional, Malta Hansen, Carolina, additional, Markenson, David, additional, Matsuyama, Tasuku, additional, McKinlay, Christopher J.D., additional, Mehrabian, Amin, additional, Merchant, Raina M., additional, Meyran, Daniel, additional, Morley, Peter T., additional, Morrison, Laurie J., additional, Nation, Kevin J., additional, Nemeth, Michael, additional, Neumar, Robert W., additional, Nicholson, Tonia, additional, Niermeyer, Susan, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, O’Neil, Brian J., additional, Orkin, Aaron M., additional, Osemeke, Osokogu, additional, Parr, Michael J., additional, Patocka, Catherine, additional, Pellegrino, Jeffrey L., additional, Perkins, Gavin D., additional, Perlman, Jeffrey M., additional, Rabi, Yacov, additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Roehr, Charles C., additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Sawyer, Taylor, additional, Schmölzer, Georg M., additional, Schnaubelt, Sebastian, additional, Semeraro, Federico, additional, Skrifvars, Markus B., additional, Smith, Christopher M., additional, Smyth, Michael A., additional, Soll, Roger F., additional, Sugiura, Takahiro, additional, Taylor-Phillips, Sian, additional, Trevisanuto, Daniele, additional, Vaillancourt, Christian, additional, Wang, Tzong-Luen, additional, Weiner, Gary M., additional, Welsford, Michelle, additional, Wigginton, Jane, additional, Wyllie, Jonathan P., additional, Yeung, Joyce, additional, Nolan, Jerry P., additional, Berg, Katherine M., additional, Abelairas-Gómez, Cristian, additional, Barcala-Furelos, Roberto, additional, Beerman, Stephen B., additional, Bierens, Joost, additional, Cacciola, Sofia, additional, Cellini, Jacqueline, additional, Claesson, Andreas, additional, Court, Rachael, additional, D’Arrigo, Sonia, additional, De Brier, Niels, additional, Dunne, Cody L., additional, Elsenga, Hylmar E., additional, Johnson, Samantha, additional, Kleven, Gunn, additional, Maconochie, Ian, additional, Mecrow, Tom, additional, Morgan, Patrick, additional, Otto, Quentin, additional, Palmieri, Tina L., additional, Parnia, Sam, additional, Pawar, Rahul, additional, Pereira, João, additional, Rudd, Sarah, additional, Scapigliati, Andrea, additional, Schmidt, Andrew, additional, Seesink, Jeroen, additional, Sempsrott, Justin R., additional, Szpilman, David, additional, Warner, David S., additional, Webber, Jonathon B., additional, and West, Rebecca L, additional

Published
2022
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61. sj-docx-1-mdm-10.1177_0272989X221099493 – Supplemental material for Noninferiority Margin Size and Acceptance of Trial Results: Contingent Valuation Survey of Clinician Preferences for Noninferior Mortality

Author

Pong, Sandra, Fowler, Robert A., Mitsakakis, Nicholas, Murthy, Srinivas, Pernica, Jeffrey M., Gilfoyle, Elaine, Bowen, Asha, Fontela, Patricia, Seto, Winnie, Science, Michelle, Hutchison, James S., Jouvet, Philippe, Rishu, Asgar, and Daneman, Nick

Subjects
111708 Health and Community Services, 111799 Public Health and Health Services not elsewhere classified, 160807 Sociological Methodology and Research Methods, FOS: Health sciences, FOS: Sociology
Abstract

Supplemental material, sj-docx-1-mdm-10.1177_0272989X221099493 for Noninferiority Margin Size and Acceptance of Trial Results: Contingent Valuation Survey of Clinician Preferences for Noninferior Mortality by Sandra Pong, Robert A. Fowler, Nicholas Mitsakakis, Srinivas Murthy, Jeffrey M. Pernica, Elaine Gilfoyle, Asha Bowen, Patricia Fontela, Winnie Seto, Michelle Science, James S. Hutchison, Philippe Jouvet, Asgar Rishu and Nick Daneman in Medical Decision Making

Published
2022
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66. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Wyckoff, Myra H., primary, Singletary, Eunice M., additional, Soar, Jasmeet, additional, Olasveengen, Theresa M., additional, Greif, Robert, additional, Liley, Helen G., additional, Zideman, David, additional, Bhanji, Farhan, additional, Andersen, Lars W., additional, Avis, Suzanne R., additional, Aziz, Khalid, additional, Bendall, Jason C., additional, Berry, David C., additional, Borra, Vere, additional, Böttiger, Bernd W., additional, Bradley, Richard, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Carlson, Jestin N., additional, Cassan, Pascal, additional, Castrén, Maaret, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Cheng, Adam, additional, Chung, Sung Phil, additional, Considine, Julie, additional, Costa-Nobre, Daniela T., additional, Couper, Keith, additional, Dainty, Katie N., additional, Davis, Peter G., additional, de Almeida, Maria Fernanda, additional, de Caen, Allan R., additional, de Paiva, Edison F., additional, Deakin, Charles D., additional, Djärv, Therese, additional, Douma, Matthew J., additional, Drennan, Ian R., additional, Duff, Jonathan P., additional, Eastwood, Kathryn J., additional, El-Naggar, Walid, additional, Epstein, Jonathan L., additional, Escalante, Raffo, additional, Fabres, Jorge G., additional, Fawke, Joe, additional, Finn, Judith C., additional, Foglia, Elizabeth E., additional, Folke, Fredrik, additional, Freeman, Karoline, additional, Gilfoyle, Elaine, additional, Goolsby, Craig A., additional, Grove, Amy, additional, Guinsburg, Ruth, additional, Hatanaka, Tetsuo, additional, Hazinski, Mary Fran, additional, Heriot, George S., additional, Hirsch, Karen G., additional, Holmberg, Mathias J., additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Hung, Kevin K.C., additional, Hsu, Cindy H., additional, Ikeyama, Takanari, additional, Isayama, Tetsuya, additional, Kapadia, Vishal S., additional, Kawakami, Mandira Daripa, additional, Kim, Han-Suk, additional, Kloeck, David A., additional, Kudenchuk, Peter J., additional, Lagina, Anthony T., additional, Lauridsen, Kasper G., additional, Lavonas, Eric J., additional, Lockey, Andrew S., additional, Malta Hansen, Carolina, additional, Markenson, David, additional, Matsuyama, Tasuku, additional, McKinlay, Christopher J.D., additional, Mehrabian, Amin, additional, Merchant, Raina M., additional, Meyran, Daniel, additional, Morley, Peter T., additional, Morrison, Laurie J., additional, Nation, Kevin J., additional, Nemeth, Michael, additional, Neumar, Robert W., additional, Nicholson, Tonia, additional, Niermeyer, Susan, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, O’Neil, Brian J., additional, Orkin, Aaron M., additional, Osemeke, Osokogu, additional, Parr, Michael J., additional, Patocka, Catherine, additional, Pellegrino, Jeffrey L., additional, Perkins, Gavin D., additional, Perlman, Jeffrey M., additional, Rabi, Yacov, additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Roehr, Charles C., additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Sawyer, Taylor, additional, Schmölzer, Georg M., additional, Schnaubelt, Sebastian, additional, Semeraro, Federico, additional, Skrifvars, Markus B., additional, Smith, Christopher M., additional, Smyth, Michael A., additional, Soll, Roger F., additional, Sugiura, Takahiro, additional, Taylor-Phillips, Sian, additional, Trevisanuto, Daniele, additional, Vaillancourt, Christian, additional, Wang, Tzong-Luen, additional, Weiner, Gary M., additional, Welsford, Michelle, additional, Wigginton, Jane, additional, Wyllie, Jonathan P., additional, Yeung, Joyce, additional, Nolan, Jerry P., additional, Berg, Katherine M., additional, Abelairas-Gómez, Cristian, additional, Barcala-Furelos, Roberto, additional, Beerman, Stephen B., additional, Bierens, Joost, additional, Cacciola, Sofia, additional, Cellini, Jacqueline, additional, Claesson, Andreas, additional, Court, Rachael, additional, D'Arrigo, Sonia, additional, De Brier, Niels, additional, Dunne, Cody L., additional, Elsenga, Hylmar E., additional, Johnson, Samantha, additional, Kleven, Gunn, additional, Maconochie, Ian, additional, Mecrow, Tom, additional, Morgan, Patrick, additional, Otto, Quentin, additional, Palmieri, Tina L., additional, Parnia, Sam, additional, Pawar, Rahul, additional, Pereira, João, additional, Rudd, Sarah, additional, Scapigliati, Andrea, additional, Schmidt, Andrew, additional, Seesink, Jeroen, additional, Sempsrott, Justin R., additional, Szpilman, David, additional, Warner, David S., additional, Webber, Jonathon B., additional, and West, Rebecca L., additional

Published
2021
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67. 2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Wyckoff, Myra H., Singletary, Eunice M., Soar, Jasmeet, Olasveengen, Theresa M., Greif, Robert, Liley, Helen G., Zideman, David, Bhanji, Farhan, Andersen, Lars W., Avis, Suzanne R., Aziz, Khalid, Bendall, Jason C., Berry, David C., Borra, Vere, B��ttiger, Bernd W., Bradley, Richard, Bray, Janet E., Breckwoldt, Jan, Carlson, Jestin N., Cassan, Pascal, Castr��n, Maaret, Chang, Wei-Tien, Charlton, Nathan P., Cheng, Adam, Chung, Sung Phil, Considine, Julie, Costa-Nobre, Daniela T., Couper, Keith, Dainty, Katie N., Davis, Peter G., de Almeida, Maria Fernanda, de Caen, Allan R., de Paiva, Edison F., Deakin, Charles D., Dj��rv, Therese, Douma, Matthew J., Drennan, Ian R., Duff, Jonathan P., Eastwood, Kathryn J., Epstein, Jonathan L., Escalante, Raffo, Fabres, Jorge G., Fawke, Joe, Finn, Judith C., Foglia, Elizabeth E., Folke, Fredrik, Freeman, Karoline, Gilfoyle, Elaine, Goolsby, Craig A., Grove, Amy, Guinsburg, Ruth, Hatanaka, Tetsuo, Hazinski, Mary Fran, Heriot, George S., Hirsch, Karen G., Holmberg, Mathias J., Hosono, Shigeharu, Hsieh, Ming-Ju, Hung, Kevin K.C., Hsu, Cindy H., Ikeyama, Takanari, Isayama, Tetsuya, Kapadia, Vishal S., Kawakami, Mandira, Kim, Han-Suk, Kloeck, David A., Kudenchuk, Peter J., Lagina, Anthony T., Lauridsen, Kasper G., Lavonas, Eric J., Lockey, Andrew S., Malta Hansen, Carolina, Markenson, David, Matsuyama, Tasuku, McKinlay, Christopher J.D., Mehrabian, Amin, Merchant, Raina M., Meyran, Daniel, Morley, Peter T., Morrison, Laurie J., Nation, Kevin J., Nemeth, Michael, Neumar, Robert W., Nicholson, Tonia, Niermeyer, Susan, Nikolaou, Nikolaos, Nishiyama, Chika, O���Neil, Brian J., Orkin, Aaron M., Osemeke, Osokogu, Parr, Michael J., Patocka, Catherine, Pellegrino, Jeffrey L., Perkins, Gavin D., Perlman, Jeffrey M., Rabi, Yacov, Reynolds, Joshua C., Ristagno, Giuseppe, Roehr, Charles C., Sakamoto, Tetsuya, Sandroni, Claudio, Sawyer, Taylor, Schm��lzer, Georg M., Schnaubelt, Sebastian, Semeraro, Federico, Skrifvars, Markus B., Smith, Christopher M., Smyth, Michael A., Soll, Roger F., Sugiura, Takahiro, Taylor-Phillips, Sian, Trevisanuto, Daniele, Vaillancourt, Christian, Wang, Tzong-Luen, Weiner, Gary M., Welsford, Michelle, Wigginton, Jane, Wyllie, Jonathan P., Yeung, Joyce, Nolan, Jerry P., Berg, Katherine M., Abelairas-G��mez, Cristian, Barcala-Furelos, Roberto, Beerman, Stephen B., Bierens, Joost, Cacciola, So���a, Cellini, Jacqueline, Claesson, Andreas, Court, Rachael, D'Arrigo, Sonia, De Brier, Niels, Dunne, Cody L., Elsenga, Hylmar E., Johnson, Samantha, Kleven, Gunn, Maconochie, Ian, Mecrow, Tom, Morgan, Patrick, Otto, Quentin, Palmieri, Tina L., Parnia, Sam, Pawar, Rahul, Pereira, Jo��o, Rudd, Sarah, Scapigliati, Andrea, Schmidt, Andrew, Seesink, Jeroen, Sempsrott, Justin R., Szpilman, David, Warner, David S., Webber, Jonathon B., and West, Rebecca L.

Subjects
610 Medicine & health
Published
2021
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68. Family presence during resuscitation in paediatric and neonatal cardiac arrest: A systematic review

Author

Dainty, Katie N., primary, Atkins, Dianne L., additional, Breckwoldt, Jan, additional, Maconochie, Ian, additional, Schexnayder, Steve M., additional, Skrifvars, Markus B., additional, Tijssen, Janice, additional, Wyllie, Jonathan, additional, Furuta, Marie, additional, Aickin, Richard, additional, Acworth, Jason, additional, Atkins, Dianne, additional, Couto, Thomaz Bittencourt, additional, Guerguerian, Anne-Marie, additional, Kleinman, Monica, additional, Kloeck, David, additional, Nadkarni, Vinay, additional, Ng, Kee-Chong, additional, Nuthall, Gabrielle, additional, Ong, Yong- Kwang Gene, additional, Reis, Amelia, additional, Rodriguez-Nunez, Antonio, additional, Schexnayder, Steve, additional, Scholefield, Barney, additional, Voorde, Patrick van de, additional, Wyckoff, Myra, additional, Liley, Helen, additional, El-Naggar, Walid, additional, Fabres, Jorge, additional, Fawke, Joe, additional, Foglia, Elizabeth, additional, Guinsburg, Ruth, additional, Hosono, Shigeharu, additional, Isayama, Tetsuya, additional, Kawakami, Mandira, additional, Kapadia, Vishal, additional, Kim, Han-Suk, additional, McKinlay, Chris, additional, Roehr, Charles, additional, Schmolzer, Georg, additional, Sugiura, Takahiro, additional, Trevisanuto, Daniele, additional, Weiner, Gary, additional, Greif, Robert, additional, Bhanji, Farhan, additional, Bray, Janet, additional, Cheng, Adam, additional, Duff, Jonathan, additional, Eastwood, Kathryn, additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Lauridsen, Kasper, additional, Lockey, Andrew, additional, Matsuyama, Tasuku, additional, Patocka, Catherine, additional, Pellegrino, Jeffrey, additional, Sawyer, Taylor, additional, Schnaubel, Sebastian, additional, and Yeung, Joyce, additional

Published
2021
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69. Clinical decision rules for termination of resuscitation during in-hospital cardiac arrest: A systematic review of diagnostic test accuracy studies

Author

Lauridsen, Kasper G., primary, Baldi, Enrico, additional, Smyth, Michael, additional, Perkins, Gavin D., additional, Greif, Robert, additional, Bigham, Blair L., additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Duff, Jonathan P., additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Iwami, Taku, additional, Lockey, Andrew S., additional, Ma, Matthew Huei-Ming, additional, Monsieurs, Koenraad G., additional, Pellegrino, Jeffrey L., additional, Yeung, Joyce, additional, Finn, Judith, additional, and Morley, Peter, additional

Published
2021
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71. Clinical outcomes from out-of-hospital cardiac arrest in low-resource settings — A scoping review

Author

Schnaubelt, S., primary, Monsieurs, K.G., additional, Semeraro, F., additional, Schlieber, J., additional, Cheng, A., additional, Bigham, B.L., additional, Garg, R., additional, Finn, J.C., additional, Greif, R., additional, Bray, Janet, additional, Breckwoldt, Jan, additional, Lauridsen, Kasper Glerup, additional, Lockey, Andrew, additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Ma, Matthew Huei-Ming, additional, Pellegrino, Jeffrey L., additional, and Yeung, Joyce, additional

Published
2020
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72. Education, Implementation, and Teams

Author

Greif, Robert, primary, Bhanji, Farhan, additional, Bigham, Blair L., additional, Bray, Janet, additional, Breckwoldt, Jan, additional, Cheng, Adam, additional, Duff, Jonathan P., additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Iwami, Taku, additional, Lauridsen, Kasper G., additional, Lockey, Andrew S., additional, Ma, Matthew Huei-Ming, additional, Monsieurs, Koenraad G., additional, Okamoto, Deems, additional, Pellegrino, Jeffrey L., additional, Yeung, Joyce, additional, Finn, Judith C., additional, Baldi, Enrico, additional, Beck, Stefanie, additional, Beckers, Stefan K., additional, Blewer, Audrey L., additional, Boulton, Adam, additional, Cheng-Heng, Liu, additional, Yang, Chi-Wie, additional, Coppola, Alison, additional, Dainty, Katie N., additional, Damjanovic, Domagoj, additional, Djärv, Therese, additional, Donoghue, Aaron, additional, Georgiou, Marios, additional, Gunson, Imogen, additional, Krob, Jamillee L., additional, Kuzovlev, Artem, additional, Ko, Ying-Chih, additional, Leary, Marion, additional, Lin, Yiqun, additional, Mancini, Mary E., additional, Matsuyama, Tasuku, additional, Navarro, Kenneth, additional, Nehme, Ziad, additional, Orkin, Aaron M., additional, Pellis, Tommaso, additional, Pflanzl-Knizacek, Lucas, additional, Pisapia, Luca, additional, Saviani, Michela, additional, Sawyer, Taylor, additional, Scapigliati, Andrea, additional, Schnaubelt, Sebastian, additional, Scholefield, Barnaby, additional, Semeraro, Federico, additional, Shammet, Salma, additional, Smyth, Michael A., additional, Ward, Abigail, additional, and Zace, Drieda, additional

Published
2020
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75. 2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations

Author

Soar, Jasmeet, primary, Maconochie, Ian, additional, Wyckoff, Myra H., additional, Olasveengen, Theresa M., additional, Singletary, Eunice M., additional, Greif, Robert, additional, Aickin, Richard, additional, Bhanji, Farhan, additional, Donnino, Michael W., additional, Mancini, Mary E., additional, Wyllie, Jonathan P., additional, Zideman, David, additional, Andersen, Lars W., additional, Atkins, Dianne L., additional, Aziz, Khalid, additional, Bendall, Jason, additional, Berg, Katherine M., additional, Berry, David C., additional, Bigham, Blair L., additional, Bingham, Robert, additional, Couto, Thomaz Bittencourt, additional, Böttiger, Bernd W., additional, Borra, Vere, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Brooks, Steven C., additional, Buick, Jason, additional, Callaway, Clifton W., additional, Carlson, Jestin N., additional, Cassan, Pascal, additional, Castrén, Maaret, additional, Chang, Wei-Tien, additional, Charlton, Nathan P., additional, Cheng, Adam, additional, Chung, Sung Phil, additional, Considine, Julie, additional, Couper, Keith, additional, Dainty, Katie N., additional, Dawson, Jennifer Anne, additional, de Almeida, Maria Fernanda, additional, de Caen, Allan R., additional, Deakin, Charles D., additional, Drennan, Ian R., additional, Duff, Jonathan P., additional, Epstein, Jonathan L., additional, Escalante, Raffo, additional, Gazmuri, Raúl J., additional, Gilfoyle, Elaine, additional, Granfeldt, Asger, additional, Guerguerian, Anne-Marie, additional, Guinsburg, Ruth, additional, Hatanaka, Tetsuo, additional, Holmberg, Mathias J., additional, Hood, Natalie, additional, Hosono, Shigeharu, additional, Hsieh, Ming-Ju, additional, Isayama, Tetsuya, additional, Iwami, Taku, additional, Jensen, Jan L., additional, Kapadia, Vishal, additional, Kim, Han-Suk, additional, Kleinman, Monica E., additional, Kudenchuk, Peter J., additional, Lang, Eddy, additional, Lavonas, Eric, additional, Liley, Helen, additional, Lim, Swee Han, additional, Lockey, Andrew, additional, Lofgren, Bo, additional, Ma, Matthew Huei-Ming, additional, Markenson, David, additional, Meaney, Peter A., additional, Meyran, Daniel, additional, Mildenhall, Lindsay, additional, Monsieurs, Koenraad G., additional, Montgomery, William, additional, Morley, Peter T., additional, Morrison, Laurie J., additional, Nadkarni, Vinay M., additional, Nation, Kevin, additional, Neumar, Robert W., additional, Ng, Kee-Chong, additional, Nicholson, Tonia, additional, Nikolaou, Nikolaos, additional, Nishiyama, Chika, additional, Nuthall, Gabrielle, additional, Ohshimo, Shinichiro, additional, Okamoto, Deems, additional, O’Neil, Brian, additional, Ong, Gene Yong-Kwang, additional, Paiva, Edison F., additional, Parr, Michael, additional, Pellegrino, Jeffrey L., additional, Perkins, Gavin D., additional, Perlman, Jeffrey, additional, Rabi, Yacov, additional, Reis, Amelia, additional, Reynolds, Joshua C., additional, Ristagno, Giuseppe, additional, Roehr, Charles C., additional, Sakamoto, Tetsuya, additional, Sandroni, Claudio, additional, Schexnayder, Stephen M., additional, Scholefield, Barnaby R., additional, Shimizu, Naoki, additional, Skrifvars, Markus B., additional, Smyth, Michael A., additional, Stanton, David, additional, Swain, Janel, additional, Szyld, Edgardo, additional, Tijssen, Janice, additional, Travers, Andrew, additional, Trevisanuto, Daniele, additional, Vaillancourt, Christian, additional, Van de Voorde, Patrick, additional, Velaphi, Sithembiso, additional, Wang, Tzong-Luen, additional, Weiner, Gary, additional, Welsford, Michelle, additional, Woodin, Jeff A., additional, Yeung, Joyce, additional, Nolan, Jerry P., additional, and Hazinski, Mary Fran, additional

Published
2019
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76. Using research to prepare for outbreaks of severe acute respiratory infection

Author

Mich, Vann, Pho, Yaty, Bory, Sotharith, Vann, Mich, Teav, Bunlor, Som, Leakhann, Jarrvisalo, Mikko J, Pulkkinen, Anni, Kuitunen, Anne, Ala-kokko, Tero, Melto, Sari, Daix, Thomas, Philippart, Francois, Antoine, Marchalot, Tiercelet, Kelly, Bruel, Cedric, Nicholas, Sedillot, Siami, Shidasp, Fabienne, Taimon, Bruyere, Raomi, Forceville, Xavier, Erickson, Simon, Campbell, Lewis, Sonawane, Ravikiran, Santamaria, John, Kol, Mark, Awasthi, Shally, Powis, Jeff, Hall, Richard, McCarthy, Anne E, Jouvet, Philippe, Opaysky, Mary Anne, Gilfoyle, Elaine, Farshait, Nataly, Martin, Dori-Ann, Griesdale, Donald, Katz, Kevin, Ruberto, Aaron J, Carrier, Francois Martin, Lamontagne, Francois, Muscedere, John, Rishu, Asgar, Sin, Wai Ching, Ngai, Wallace Chun Wai, Young, Paul, Forrest, Annette, Kazemi, Alex, Henderson, Seton, Browne, Troy, Ganeshalingham, Anusha, McConnochie, Rachael, Cho, Jae Hwa, Park, Tai Sun, Sim, Yun Su, Chang, Youjin, Lee, Heung Bum, Park, Seung Yong, Chan, Wai Ming, Lee, Won-Yeon, Wallace, David J, Angus, Derek C, Charles, Anthony G, van Doom, H Rogier, Kinh, Nguyen Van, Trung, Nguyen Vu, Prin, Meghan, Twagirumugabe, Theogene, Umuhire, Olivier Felix, Sylvain, Habarurema, Al Qasim, Eman, Heraud, Jean-Michel, Raberahona, Mihaja, Rabarison, Joelinotahiana Hasina, Patrigeon, Santiago Perez, Ramirez-Venegas, Alejandra, Melendez, Javier Araujo, Guerrero, M Lourdes, Mambule, Ivan, Ochieng, Otieno George, Nadjm, Behzad, Li, Iris Wai Sum, Choi, Won-Il, Florence, Komurian-Pradel, Arabi, Yaseen M, West, T Eoin, Riviello, Elisabeth D, Parke, Rachael, Djillali, Annane E, Fowler, Robert, Murthy, Srinivas, Nichol, Alistair, Cheng, Allen C, Semple, Calum, George, Maya, Valkonen, Miia, McArthur, Colin, Carson, Gail, O'Neill, Genevieve, Cobb, J Perren, Dunning, Jake, Chiche, Jean-Daniel, Huh, Jin-Won, Marshall, John, Rello, Jordi, Guillebaud, Julia, Razanazatovo, Norosoa, Otieno, Juilett Wambura, Green, Karen, Rowan, Kathy, Baillie, John Kenneth, Merson, Laura, Hsu, Li Yang, Christian, Michael D, Egi, Moritoki, Shindo, Nahoko, Horby, Peter, Pardinaz-Solis, Raul, Ubiergo, Sebastian Ugarte, Webb, Steve AR, Uyeki, Timothy M, Gordon, Anthony C, Paterson, David L, Everett, Dean, Giamarellos-Bourboulis, Evangelos J, Longuere, Kajsa-Stina, Maslove, David, Ohuma, Eric, Growl, Gloria, PedutemHumber, Theresa, EllazarHumber, Edward, Bahinskaya, Ilona, Osbourne-Townsend, Joan, Bentley, Andrew, Goodson, Jennifer, Welters, Ingeborg, Malik, Nadia, Browne, TS, Mahesh, Vinaya, Investigators, SPRINT-SARI, HUS Perioperative, Intensive Care and Pain Medicine, University of Helsinki, Anestesiologian yksikkö, University College Dublin [Dublin] (UCD), Monash University [Melbourne], We acknowledge support from the National Health and Medical Research Council in Australia, the Australia New Zealand Intensive Care Society Clinical Trials Group and the Seventh Framework Program in Europe, which have facilitated the progress that has been made for central project infrastructure. Data collection was funded locally by local research coordinators and investigators, including the International Respiratory and Severe Illness Center, University of Washington., Collaborators Vann Mich, Khmer Soviet Friend Hospital. Yaty Pho, Khmer Soviet Friend Hospital. Sotharith Bory, Calmette Hospital and University of Health Sciences. Mich Vann, Khmer-Soviet Friendship Hospital and University of Health Sciences. Bunlor Teav, Takeo Provincial Hospital. Leakhann Som, National Pediatric Hospital. Mikko J Jarrvisalo, Turku university hospital, ICU. Anni Pulkkinen, Central Hospital of Central Finland. Anne Kuitunen, Tampere University Hospital. Tero Ala-kokko, Oulu University Hospital, Research Group of Anesthesiology, Surgery and Intensive Care Medicine. Sari. Melto, South Karelia Central Hospital. Thomas DAIX, Reanimation polyvalente, CHU Dupuytren, Limoges, France and Inserm CIC 1435, CHU Dupuytren, Limoges, France. Francois Philippart, Intensive Care Unit. Marchalot Antoine, Dieppe General Hospital. Kelly Tiercelet, Groupe hospitalier Paris Saint Joseph. Cedric Bruel, Groupe hospitalier Paris Saint Joseph. BRUYERE Remi, Centre Hospitalier Fleyriat. Sedillot Nicholas, Centre Hospitalier Fleyriat. Shidasp SIAMI, General Intensive Care Medicine, Sud Essonne Hospital Etampes. Marchalot Antoine, Centre Hospitalier Dieppe. Taimon Fabienne, Service de Medecine Intensive et Reanimation, Rouen University Hospital (G.B.), and Normandie University, Universite de Rouen, U1096, Rouen University Hospital. Philippart, Groupe hospitalier Paris Saint joseph. Raomi Bruyere, Service de reanimation. Centre Hospitalier Fleyriat. Xavier Forceville, Grand Hopital de l'Est Francilien. Simon Erickson, Perth Children's Hospital. Lewis Campbell, Royal Darwin Hospital. Ravikiran Sonawane, Rockingham General Hospital. John Santamaria, St Vincent's Hospital (Melbourne). Mark Kol, Concord Hospital. Shally Awasthi, King George's Medical University. Jeff Powis, Michael Garron Hospital. Richard Hall, Dalhousie University. Anne E McCarthy, University of Ottawa and the Ottawa Hospital. Philippe Jouvet, Ste-Justine Hospital and Research Center. Mary Anne Opavsky, Joseph Brant Hospital. Elaine Gilfoyle, University of Calgary. Nataly Farshait, Humber River Hospital. Dori-Ann Martin, University of Calgary. Donald Griesdale, Department of Anesthesiology, Pharmacology & Therapeutics Department of Medicine, Divisions of Critical Care Medicine & Neurology University of British Columbia. Kevin Katz, North York General Hospital. Aaron J. Ruberto, Queen's University & Kingston Health Sciences Centre. Francois Martin Carrier, Centre Hospitalier de l'Universite de Montreal. Francois Lamontagne, Universite de Sherbrooke. John Muscedere, Queens University. Asgar Rishu, Sunnybrook Health Sciences Centre. Wai Ching Sin, Department of Adult Intensive Care Unit, Queen Mary Hospital. Wallace Chun Wai Ngai, Department of Adult Intensive Care Unit, Queen Mary Hospital. Paul Young, Medical Research Institute of New Zealand. Dr Annette Forrest, Waikato Hospital. Alex Kazemi, Middlemore Hospital. Seton Henderson, Christchurch Hospital. Troy Browne, Tauranga Hospital. Anusha Ganeshalingham, Starship Hospital. Rachael McConnochie, Department of Critical Care Medicine, Auckland City Hospital. Jae Hwa Cho, Yonsei University. Tai Sun Park, Hanyang University Guri Hospital. Yun Su Sim, Hallym University Kangnam Sacred Hospital. Youjin Chang, Inje University, College of Medicine, Sanggye Paik Hospital. Heung Bum Lee, Chonbuk National University Hospital. Seung Yong Park, Chonbuk National University Hospital. Wai Ming Chan, Department of Adult Intensive Care Unit, Queen Mary Hospital, Hong Kong. Won-Yeon Lee, Yonsei University Wonju College of Medicine. David J. Wallace, University of Pittsburgh School of Medicine. Derek C. Angus, University of Pittsburgh School of Medicine. Anthony G Charles, University of North Carolina at Chapel Hill. H Rogier van Doorn, Oxford University Clinical Research Unit. Nguyen Van Kinh, National Hospital for Tropical Diseases. Nguyen Vu Trung, National Hospital for Tropical Diseases. Meghan Prin, Columbia University College of Physicians & Surgeons. Theogene Twagirumugabe, University of Rwanda /College of Medicine and Health Sciences. Olivier Felix Umuhire, Department of Anesthesia, Emergency Medicine and Critical Care. University of Rwanda. Habarurema Sylvain, Centre hospitalier Universitaire de Butare(CHUB). Eman Al Qasim, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center. Jean-Michel Heraud, Institut Pasteur de Madagascar. Mihaja Raberahona, University Hospital Joseph Raseta Befelatanana. Joelinotahiana Hasina Rabarison, Insttut Pasteur de Madagascar. Santiago Perez Patrigeon, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Subirán. Alejandra Ramirez-Venegas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas. Javier Araujo Meléndez, Hospital Central 'Dr. Ignacio Morones Prieto'. M. Lourdes Guerrero, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiren. Ivan Mambule, Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health University of Liverpool and Malawi-Liverpool-Wellcome Trust, Clinical Research Programme. Otieno George Ochieng, Kijabe Mission Hospital. Behzad Nadjm, Imperial College Healthcare NHS Trust, GBR. Iris Wai Sum Li, Queen Mary Hospital, School of Public Health, the University of Hong Kong. Won-Il Choi, Department of Medicine, Keimyung University, Dongsan Hospital. Komurian-Pradel Florence, Fondation Merieux. Yaseen M Arabi, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Intensive Care Department, King Abdulaziz Medical City. T. Eoin West, University of Washington. Elisabeth D Riviello, Harvard Medical School and Beth Israel Deaconess Medical Center. Rachael Parke, Cardiothoracic and Vascular ICU, Auckland City Hospital. AnnaneE Djillali, Raymond Poincare Hospital (APHP) Unievrsity of Versailles SQY/University Paris Saclay. Robert Fowler, Interdepartmental Division of Critical Care Medicine, University of Toronto. Srinivas Murthy, Department of Pediatrics. Alistair Nichol, University College Dublin / Monash University. Allen C Cheng, School of Public Health and Preventive Medicine, Monash University. Calum Semple, University of Liverpool. Maya George, Australian and New Zealand Intensive Care Research Centre, Monash University. Miia Valkonen, University of Helsinki and Helsinki University Hospital. Colin McArthur, Auckland City Hospital (DCCM 82). Gail Carson, University of Oxford. Genevieve O'Neill, Australian and New Zealand Intensive Care Research Centre, Monash University. J. Perren Cobb, University of Southern California. Jake Dunning, University of Oxford, Imperial College London. Jean-Daniel Chiche, Hopitaux Universitaire Paris Centre, site Cochin. Jin-Won Huh, ASAN Medical Center. John Marshall, St. Michael's Hospital. Jordi Rello, Ciberes & Vall d'Hebron University Hospital, Barcelona, Spain. Julia Guillebaud, Institut Pasteur de Madagascar. Norosoa Razanazatovo, Institut Pasteur de Madagascar. Juilett Wambura Otieno, KEMRI-Wellcome Trust Research Programme. Karen Green, Toronto Invasive Bacterial Diseases Network. Kathy Rowan, Intensive Care National Audit and Research Centre. John Kenneth Baillie, Roslin Institute, University of Edinburgh. Laura Merson, Infectious Diseases Data Observatory, Oxford, UK, Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, Oxford University, Oxford UK. Li Yang Hsu, National University of Singapore. Michael D. Christian, Essex & Herts Air Ambulance Trust. Miia Valkonen, Helsinki University Central Hospital. Moritoki Egi, Kobe University Hospital. Nahoko Shindo, World Health Organization. Peter Horby, University of Oxford. Raul Pardinaz-Solis, Nuffield Department of Medicine, University of Oxford. Sebastián Ugarte Ubiergo, Universidad Andrés Bello. Steve AR Webb, Monash University. Timothy M. Uyeki, Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia USA. Anthony C Gordon, Imperial College London. David L Paterson, University of Queensland Centre. Dean Everett, University of Edinburgh, The Queens Medical Research Institute and Malawi-Liverpool-Wellcome Trust, Clinical Research Programme. Evangelos J. Giamarellos-Bourboulis, National and Kapodistrian University of Athens, Medical School. Kajsa-Stina Longuere, University of Oxford. David Maslove, Queens University. Eric Ohuma, Oxford University. Gloria Crowl, Michael Garron Hospital. Theresa PedutemHumber, River Hospital. Edward EllazarHumber, River Hospital. Ilona Bahinskaya, University Health Network TGH MOT. Joan Osbourne-Townsend, Humber River Hospital. Andrew Bentley, University of Manchester. Ingeborg Welters, University of Liverpool. Nadia Malik, MountSinai Hospital/ William Osler Health Centre. Dr T S Browne, Tauranga Hospital. Jennifer Goodson, Tauranga Hospital. Vinaya Mahesh, North York General Hospital., and Carson, G

Subjects
medicine.medical_specialty, INTENSIVE-CARE-UNIT, global health, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Intensive care, Case fatality rate, Epidemiology, Global health, medicine, pneumonia, 030212 general & internal medicine, Public, Environmental & Occupational Health, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases, Practice, OUTCOMES, Science & Technology, business.industry, Health Policy, Public Health, Environmental and Occupational Health, Outbreak, 030208 emergency & critical care medicine, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology, 3126 Surgery, anesthesiology, intensive care, radiology, Intensive care unit, 3. Good health, critical care, REAL-TIME SURVEILLANCE, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Observational study, SOFA score, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, SPRINT-SARI investigators, business, influenza, Life Sciences & Biomedicine, Demography, outbreak preparedness
Abstract

International audience; Severe acute respiratory infections (SARI) remain one of the leading causes of mortality around the world in all age groups. There is large global variation in epidemiology, clinical management and outcomes, including mortality. We performed a short period observational data collection in critical care units distributed globally during regional peak SARI seasons from 1 January 2016 until 31 August 2017, using standardised data collection tools. Data were collected for 1 week on all admitted patients who met the inclusion criteria for SARI, with follow-up to hospital discharge. Proportions of patients across regions were compared for microbiology, management strategies and outcomes. Regions were divided geographically and economically according to World Bank definitions. Data were collected for 682 patients from 95 hospitals and 23 countries. The overall mortality was 9.5%. Of the patients, 21.7% were children, with case fatality proportions of 1% for those less than 5 years. The highest mortality was in those above 60 years, at 18.6%. Case fatality varied by region: East Asia and Pacific 10.2% (21 of 206), Sub-Saharan Africa 4.3% (8 of 188), South Asia 0% (0 of 35), North America 13.6% (25 of 184), and Europe and Central Asia 14.3% (9 of 63). Mortality in low-income and low-middle-income countries combined was 4% as compared with 14% in high-income countries. Organ dysfunction scores calculated on presentation in 560 patients where full data were available revealed Sequential Organ Failure Assessment (SOFA) scores on presentation were significantly associated with mortality and hospital length of stay. Patients in East Asia and Pacific (48%) and North America (24%) had the highest SOFA scores of >12. Multivariable analysis demonstrated that initial SOFA score and age were independent predictors of hospital survival. There was variability across regions and income groupings for the critical care management and outcomes of SARI. Intensive care unit-specific factors, geography and management features were less reliable than baseline severity for predicting ultimate outcome. These findings may help in planning future outbreak severity assessments, but more globally representative data are required.

Published
2019

77. Using research to prepare for outbreaks of severe acute respiratory infection

Author

Mich, Vann Pho, Yaty Bory, Sotharith Vann, Mich Teav, Bunlor Som, Leakhann Jarrvisalo, Mikko J. Pulkkinen, Anni and Kuitunen, Anne Ala-kokko, Tero Melto, Sari Daix, Thomas and Philippart, Francois Antoine, Marchalot Tiercelet, Kelly and Bruel, Cedric Nicholas, Sedillot Siami, Shidasp Fabienne, Taimon Bruyere, Raomi Forceville, Xavier Erickson, Simon and Campbell, Lewis Sonawane, Ravikiran Santamaria, John Kol, Mark Awasthi, Shally Powis, Jeff Hall, Richard McCarthy, Anne E. Jouvet, Philippe Opaysky, Mary Anne Gilfoyle, Elaine and Farshait, Nataly Martin, Dori-Ann Griesdale, Donald and Katz, Kevin Ruberto, Aaron J. Carrier, Francois Martin and Lamontagne, Francois Muscedere, John Rishu, Asgar Sin, Wai Ching Ngai, Wallace Chun Wai Young, Paul Forrest, Annette and Kazemi, Alex Henderson, Seton Browne, Troy and Ganeshalingham, Anusha McConnochie, Rachael Cho, Jae Hwa and Park, Tai Sun Sim, Yun Su Chang, Youjin Lee, Heung Bum and Park, Seung Yong Chan, Wai Ming Lee, Won-Yeon Wallace, David J. Angus, Derek C. Charles, Anthony G. van Doom, H. Rogier and Nguyen Van Kinh Nguyen Vu Trung Prin, Meghan and Twagirumugabe, Theogene Umuhire, Olivier Felix Sylvain, Habarurema Al Qasim, Eman Heraud, Jean-Michel Raberahona, Mihaja Rabarison, Joelinotahiana Hasina Patrigeon, Santiago Perez Ramirez-Venegas, Alejandra Melendez, Javier Araujo and Guerrero, M. Lourdes Mambule, Ivan Ochieng, Otieno George and Nadjm, Behzad Li, Iris Wai Sum Choi, Won-Il Florence, Komurian-Pradel Arabi, Yaseen M. West, T. Eoin Riviello, Elisabeth D. Parke, Rachael Djillali, Annane E. Fowler, Robert Murthy, Srinivas Nichol, Alistair Cheng, Allen C. and Semple, Calum George, Maya Valkonen, Miia McArthur, Colin and Carson, Gail O'Neill, Genevieve Cobb, J. Perren Dunning, Jake Chiche, Jean-Daniel Huh, Jin-Won Marshall, John and Rello, Jordi Guillebaud, Julia Razanazatovo, Norosoa Otieno, Juilett Wambura Green, Karen Rowan, Kathy Baillie, John Kenneth Merson, Laura Hsu, Li Yang Christian, Michael D. and Egi, Moritoki Shindo, Nahoko Horby, Peter Pardinaz-Solis, Raul Ubiergo, Sebastian Ugarte Webb, Steve A. R. Uyeki, Timothy M. Gordon, Anthony C. Paterson, David L. Everett, Dean Giamarellos-Bourboulis, Evangelos J. Longuere, Kajsa-Stina and Maslove, David Ohuma, Eric Growl, Gloria PedutemHumber, Theresa EllazarHumber, Edward Bahinskaya, Ilona and Osbourne-Townsend, Joan Bentley, Andrew Goodson, Jennifer and Welters, Ingeborg Malik, Nadia Browne, T. S. Mahesh, Vinaya and SPRINT-SARI Investigators

Abstract

Severe acute respiratory infections (SARI) remain one of the leading causes of mortality around the world in all age groups. There is large global variation in epidemiology, clinical management and outcomes, including mortality. We performed a short period observational data collection in critical care units distributed globally during regional peak SARI seasons from 1 January 2016 until 31 August 2017, using standardised data collection tools. Data were collected for 1 week on all admitted patients who met the inclusion criteria for SARI, with follow-up to hospital discharge. Proportions of patients across regions were compared for microbiology, management strategies and outcomes. Regions were divided geographically and economically according to World Bank definitions. Data were collected for 682 patients from 95 hospitals and 23 countries. The overall mortality was 9.5%. Of the patients, 21.7% were children, with case fatality proportions of 1% for those less than 5 years. The highest mortality was in those above 60 years, at 18.6%. Case fatality varied by region: East Asia and Pacific 10.2% (21 of 206), Sub-Saharan Africa 4.3% (8 of 188), South Asia 0% (0 of 35), North America 13.6% (25 of 184), and Europe and Central Asia 14.3% (9 of 63). Mortality in low-income and low-middle-income countries combined was 4% as compared with 14% in high-income countries. Organ dysfunction scores calculated on presentation in 560 patients where full data were available revealed Sequential Organ Failure Assessment (SOFA) scores on presentation were significantly associated with mortality and hospital length of stay. Patients in East Asia and Pacific (48%) and North America (24%) had the highest SOFA scores of >12. Multivariable analysis demonstrated that initial SOFA score and age were independent predictors of hospital survival. There was variability across regions and income groupings for the critical care management and outcomes of SARI. Intensive care unit-specific factors, geography and management features were less reliable than baseline severity for predicting ultimate outcome. These findings may help in planning future outbreak severity assessments, but more globally representative data are required.

Published
2019

78. Code Team Structure and Training in the Pediatric Resuscitation Quality International Collaborative.

Author

Pfeiffer, Stephen, Lauridsen, Kasper Glerup, Wenger, Jesse, Hunt, Elizabeth A., Haskell, Sarah, Atkins, Dianne L., Duval-Arnould, Jordan M., Knight, Lynda J., Cheng, Adam, Gilfoyle, Elaine, Su, Felice, Balikai, Shilpa, Skellett, Sophie, Mok Yee Hui, Niles, Dana E., Roberts, Joan S., Nadkarni, Vinay M., Tegtmeyer, Ken, Dewan, Maya, and Hui, Mok Yee

Published
2021
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79. Présence de la famille pendant la réanimation: évaluation des besoins en matière d’éducation, de politiques et de position au Canada.

Author

Deacon, Amanda, O'Neill, Thomas A., and Gilfoyle, Elaine

Abstract

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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80. Qualité des soins cliniques prodigués pendant un arrêt cardiaque pédiatrique simulé : une étude basée sur de la simulation.

Author

Garcia-Jorda, Dailys, Martin, Dori-Ann, Camphaug, Jenna, Bissett, Wendy, Spence, Tanya, Mahoney, Meagan, Cheng, Adam, Lin, Yiqun, and Gilfoyle, Elaine

Subjects
CARDIOPULMONARY resuscitation, COMPUTER simulation, CARDIAC arrest, VIDEO recording, LONGITUDINAL method
Abstract

Copyright of Canadian Journal of Anaesthesia / Journal Canadien d'Anesthésie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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83. Intensive Care Unit Capacity Measure

Author

Opgenorth, Dawn, primary, Stelfox, Henry T., additional, Gilfoyle, Elaine, additional, Gibney, R. T. Noel, additional, Meier, Michael, additional, Boucher, Paul, additional, McKinlay, David, additional, McIntosh, Christiane N. Job, additional, Wang, Xiaoming, additional, Zygun, David A., additional, and Bagshaw, Sean M., additional

Published
2018
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88. A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock

Author

Menon, Kusum, primary, McNally, Dayre, additional, O’Hearn, Katharine, additional, Acharya, Anand, additional, Wong, Hector R., additional, Lawson, Margaret, additional, Ramsay, Tim, additional, McIntyre, Lauralyn, additional, Gilfoyle, Elaine, additional, Tucci, Marisa, additional, Wensley, David, additional, Gottesman, Ronald, additional, Morrison, Gavin, additional, and Choong, Karen, additional

Published
2017
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89. Healthcare Provider Perceptions of Causes and Consequences of ICU Capacity Strain in a Large Publicly Funded Integrated Health Region: A Qualitative Study

Author

Bagshaw, Sean M., primary, Opgenorth, Dawn, additional, Potestio, Melissa, additional, Hastings, Stephanie E., additional, Hepp, Shelanne L., additional, Gilfoyle, Elaine, additional, McKinlay, David, additional, Boucher, Paul, additional, Meier, Michael, additional, Parsons-Leigh, Jeanna, additional, Gibney, R. T. Noel, additional, Zygun, David A., additional, and Stelfox, Henry T., additional

Published
2017
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94. Part 8: Education, Implementation, and Teams

Author

Bhanji, Farhan, primary, Finn, Judith C., additional, Lockey, Andrew, additional, Monsieurs, Koenraad, additional, Frengley, Robert, additional, Iwami, Taku, additional, Lang, Eddy, additional, Ma, Matthew Huei-Ming, additional, Mancini, Mary E., additional, McNeil, Mary Ann, additional, Greif, Robert, additional, Billi, John E., additional, Nadkarni, Vinay M., additional, Bigham, Blair, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Brooks, Steven C., additional, Cheng, Adam, additional, Donoghue, Aaron J., additional, Duff, Jonathan P., additional, Edelson, Dana P., additional, Fischer, Henrik, additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Kloeck, David A., additional, Ko, Patrick, additional, Leary, Marion, additional, Olasveengen, Theresa M., additional, Rittenberger, Jon C., additional, Schultz, Robert D., additional, Stub, Dion, additional, Triska, Zuzana, additional, Wolbrink, Traci A., additional, Yang, Chih-Wei, additional, and Yeung, Joyce, additional

Published
2015
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95. Part 8: Education, implementation, and teams

Author

Finn, Judith C., primary, Bhanji, Farhan, additional, Lockey, Andrew, additional, Monsieurs, Koenraad, additional, Frengley, Robert, additional, Iwami, Taku, additional, Lang, Eddy, additional, Ma, Matthew Huei-Ming, additional, Mancini, Mary E., additional, McNeil, Mary Ann, additional, Greif, Robert, additional, Billi, John E., additional, Nadkarni, Vinay M., additional, Bigham, Blair, additional, Bray, Janet E., additional, Breckwoldt, Jan, additional, Brooks, Steven C., additional, Cheng, Adam, additional, Donoghue, Aaron J., additional, Duff, Jonathan P., additional, Edelson, Dana P., additional, Fischer, Henrik, additional, Gilfoyle, Elaine, additional, Hsieh, Ming-Ju, additional, Kloeck, David A., additional, Ko, Patrick, additional, Leary, Marion, additional, Monsieurs, Koenraad G., additional, Olasveengen, Theresa M., additional, Rittenberger, Jon C., additional, Schultz, Robert D., additional, Stub, Dion, additional, Triska, Zuzana, additional, Wolbrink, Traci A., additional, Yang, Chih-Wei, additional, and Yeung, Joyce, additional

Published
2015
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97. Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial.

Author

O'Hearn, Katharine, McNally, Dayre, Choong, Karen, Acharya, Anand, Wong, Hector R., Lawson, Margaret, Ramsay, Tim, McIntyre, Lauralyn, Gilfoyle, Elaine, Tucci, Marisa, Wensley, David, Gottesman, Ronald, Morrison, Gavin, Menon, Kusum, and Canadian Critical Care Trials Group

Subjects
STEROID drugs, SHOCK (Pathology), HORMONE therapy, ADRENOCORTICAL hormones, RANDOMIZED controlled trials, HYDROCORTISONE, DRUG side effects, THERAPEUTICS, AGE distribution, COMBINED modality therapy, COMPARATIVE studies, EXPERIMENTAL design, FLUID therapy, INTRAVENOUS therapy, RESEARCH methodology, MEDICAL cooperation, RESEARCH protocols, RESEARCH, RESEARCH funding, STATISTICAL sampling, SEPTIC shock, TIME, VASOCONSTRICTORS, PILOT projects, EVALUATION research, TREATMENT effectiveness, BLIND experiment, PARENTERAL infusions, DIAGNOSIS
Abstract

Background: Physicians often administer corticosteroids for the treatment of fluid and vasoactive infusion dependent pediatric shock. This use of corticosteroids is controversial, however, and has never been studied in a pediatric randomized controlled trial (RCT). This pilot trial will determine the feasibility of a larger RCT on the role of corticosteroids in pediatric shock.Methods/design: Steroids in Fluid and/or Vasoactive Infusion Dependent Pediatric Shock (STRIPES) is a pragmatic, seven-center, double-blind, pilot RCT. We aim to randomize 72 pediatric patients with fluid and vasoactive infusion dependent shock to receive either hydrocortisone or a saline placebo for 7 days or until clinical stability, whichever occurs first. The primary outcome of this pilot trial is the feasibility of recruitment, defined as the number of patients enrolled over a 1-year period. Secondary outcomes include the frequency of, and reasons for, open-label steroid use, protocol adherence, incidence of mortality and corticosteroid-associated adverse events, time to discontinuation of inotropes, and feasibility of blood sampling.Discussion: Corticosteroids are used for the treatment of pediatric shock without sufficient evidence to support this practice. While there is a scientific rationale and limited data supporting their use in this setting, there is also evidence from other populations suggesting potential harm. The STRIPES pilot study will assess the feasibility of a larger, much needed trial powered for clinically important outcomes.Trial Registration: ClinicalTrials.gov: NCT02044159. [ABSTRACT FROM AUTHOR]

Published
2016
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100. Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster

Author

Percival-Smith, Anthony, Weber, Jennifer, Gilfoyle, Elaine, and Wilson, Peggy

Abstract

Both Proboscipedia (PB) and Sex Combs Reduced (SCR) activities are required for determination of proboscis identity. Here we show that simultaneous removal of PB and SCR activity results in a proboscis-to-antenna transformation. Dominant negative PB molecules inhibit the activity of SCR indicating that PB and SCR interact in a multimeric protein complex in determination of proboscis identity. These data suggest that the expression pattern of PB and SCR and the ability of PB and SCR to interact in a multimeric complex control the determination of four adult structures. The absence of PB and SCR expression leads to antennal identity; expression of only PB leads to maxillary palp identity; expression of only SCR leads to tarsus identity; and expression of both PB and SCR, which results in the formation of a PB-SCR-containing complex, leads to proboscis identity. However, the PB-SCR interaction is not detectable in vitro and is not detectable genetically in the head region during embryogenesis, indicating the PB-SCR interaction may be regulated and indirect. This regulation may also explain why ectopic expression of SCRQ50K and SCR do not result in the expected transformation of the maxillary palp to an antennae and proboscis, respectively. Previous analysis of the requirements of SCR activity for adult pattern formation has shown that ectopic expression of SCR results in an antenna-to-tarsus transformation, but removal of SCR activity in a clone of cells does not result in a tarsus-to-arista transformation. Here we show in five independent assays the reason for this apparent contradictory requirement of SCR activity in tarsus determination. SCR activity is required cell nonautonomously for tarsus determination. Specifically, we propose that SCR activity is required in the mesodermal adepithelial cells of all leg imaginal discs at late second/early third instar larval stage for the synthesis of a mesoderm-specific, tarsus-inducing, signaling factor, which after secretion from the adepithelial cells acts on the overlaying ectodermal cells determining tarsus identity. This study characterizes a combinatorial interaction between two HOX proteins; a mechanism that may have a major role in patterning the anterior-posterior axis of other animals.

Published
1997
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