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85 results on '"Fogh-Andersen, Niels"'

66. Preface

Author

Fogh-andersen, Niels, primary, Gøthgen, Ivar H., additional, Kokholm, Gert, additional, Siggaard-andersen, Ole, additional, and Wimberley, Peter D., additional

Published
1990
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76. Free Calcium Ion Concentration in Pregnancy: A longitudinal study on 22 normal pregnant women

Author

Fogh-Andersen, Niels and Schultz-Larsen, Peter

Abstract

302 samples from 22 normal pregnancies were frozen and kept for the analysis of free calcium ion concentration [Ca2+ 7.4 at 37°c and pH 7.40, after equilibration with CO2. Individual regressions were performed, and the concentration was found to increase slightly but significantly (5%, p<0.005) with the progress of the pregnancy. This increase excludes hypocalcemia as the cause of parathyroid overactivity during pregnancy, and a higher set point of the parathyrin (PTH) secretion is suggested.

Published
1981
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77. Cyclosporineinduced hypertension and decline in renal function in healthy volunteers

Author

Hansen, Jesper Melchior, Fogh-Andersen, Niels, Christensen, Niels Juel, and Strandgaard, Svend

Abstract

To investigate the effect of cyclosporine A (CsA; Sandimmun Neoral) on systemic and renal hemodynamics, tubular function, and sodium excretion in healthy volunteers. Furthermore, we studied whether CsA enhances the systemic and renal hemodynamic sensitivity to norepinephrine.

Published
1997

85. Approved IFCC recommendation on reporting results for blood glucose (abbreviated).

Author

D'Orazio P, Burnett RW, Fogh-Andersen N, Jacobs E, Kuwa K, Külpmann WR, Larsson L, Lewenstam A, Maas AH, Mager G, Naskalski JW, and Okorodudu AO

Subjects
Blood Chemical Analysis standards, Diabetes Mellitus classification, Humans, Plasma, Blood Glucose analysis, Blood Specimen Collection standards, Diabetes Mellitus diagnosis
Abstract

In current clinical practice, plasma and blood glucose are used interchangeably with a consequent risk of clinical misinterpretation. In human blood, glucose, like water, is distributed between erythrocytes and plasma. The molality of glucose (amount of glucose per unit of water mass) is the same throughout the sample, but the concentration is higher in plasma because the concentration of water and, therefore, glucose is higher in plasma than in erythrocytes. Different devices for the measurement of glucose may detect and report fundamentally different quantities. Different water concentrations in calibrators, plasma, and erythrocyte fluid can explain some of the differences. Results of glucose measurements depend on sample type and on whether methods require sample dilution or use biosensors in undiluted samples. If the results are mixed up or used indiscriminately, the differences may exceed the maximum allowable error of glucose determinations for diagnosing and monitoring diabetes mellitus, and complicate the treatment. The goal of the IFCC Scientific Division Working Group on Selective Electrodes and Point of Care Testing (IFCC-SD, WG-SEPOCT) is to reach a global consensus on reporting results. The document recommends reporting the concentration of glucose in plasma (with the unit mmol/L), irrespective of sample type or measurement technique. A constant factor of 1.11 is used to convert concentration in whole blood to the equivalent concentration in the pertinent plasma. The conversion will provide harmonized results, facilitating the classification and care of patients and leading to fewer therapeutic misjudgments.

Published
2005
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