1,487 results on '"Fiorucci, Stefano"'
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52. Modeling inflammatory bowel disease by intestinal organoids
53. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
54. Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling
55. TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β‐catenin signalling
56. Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury
57. GDF15 in Vascular and Liver Metabolic Disorders: A Novel Therapeutic Target
58. Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges
59. Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases
60. Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury.
61. Immunomodulatory functions of FXR
62. Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
63. NCX-1000: a liver-specific NO donor
64. Isoswinholide B and swinholide K, potently cytotoxic dimeric macrolides from Theonella swinhoei
65. NO-Releasing NSAIDs Modulate Cytokine Secretion
66. Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists.
67. Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa
68. Next generation sequencing analysis of gastric cancer identifies the leukemia inhibitory factor receptor (LIFR) as a driving factor in gastric cancer progression and as a predictor of poor prognosis
69. Role of mRAGEs and ACE2 in SARS-CoV-2-Related Inflammation
70. Tu1111: REGULATION OF INTESTINAL ACE2 EXPRESSION BY THE BILE ACID RECEPTOR GPBAR1 IS MEDIATED BY A GPBAR1/GLP-1/GLP-1R AXIS
71. Mo1353: DEVELOPMENT OF A DUAL GPBAR1 AND CYSTLTR1 MODULATOR TO PREVENT HEPATIC DAMAGE AND LIVER FIBROSIS
72. Tu1304: ROLE OF A DUAL GPBAR1/CYSLT1R MODULATOR REVERSES LIVER INJURY AND FIBROSIS IN A RODENT MODEL OF NASH
73. Preface
74. Sa1541: DISCOVERY OF A NOVEL CYSTEINYL-LEUKOTRIENE-RECEPTOR 1 ANTAGONIST AND BILE ACID RECEPTOR GPBAR1 AGONIST THAT REDUCES INFLAMMATION IN A MOUSE MODEL OF COLITIS
75. Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
76. Modeling Inflammatory Bowel Disease by Intestinal Organoids
77. How Smell Regulates Metabolism: The Role Of Ectopically Expressed Olfactory Receptors In Lipid and Glucose Homeostasis
78. Development of Effective and Safe Analgesic and Anti-Inflammatory Drugs: Harnessing Natural Substances for Clinical Solutions
79. GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
80. Molecular Docking and Dynamics Simulation Studies of a Dataset of NLRP3 In-flammasome Inhibitors
81. Combinatorial targeting of GPBAR1 and CYSLTR1 reveals a mechanistic role for bile acids and leukotrienes in drug induced liver injury
82. 774 FXR AGONISM AND PRIMARY BILE ACIDS: DRIVERS OF IMMUNEESCAPE IN INTESTINAL GASTRIC CANCER (GC)
83. Sa1563 BAR502 AS A PROMISING THERAPY FOR METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS: INSIGHTS FROM MURINE MODEL STUDIES
84. Su1492 BILE ACIDS AS ENDOGENOUS ANTAGONISTS OF LEUKEMIA INHIBITORY FACTOR RECEPTOR (LIFR) IN GASTRIC CANCER (GC): IMPLICATIONS FOR THERAPEUTIC INTERVENTIONS
85. Tu1726 GPBAR1 AGONISM AND SIMULTANEOUS RORΓT INVERSE AGONISM AS A NOVEL PROMISING THERAPY FOR THE TREATMENT OF IBD
86. 913 THE BILE ACIDS METABOLITES PRODUCED BY THE INTESTINAL MICROBIOTA ACT AS GPBAR1 AGONIST AND RORΓT INVERSE AGONIST DETERMINING THE COURSE OF INFLAMMATORY BOWEL DISEASE
87. Organoids as ex vivo culture system to investigate infection-host interaction in gastric pre-carcinogenesis.
88. Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics
89. Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling
90. Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity
91. TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β‐catenin signalling.
92. Rescuing inflammation By Inflammasome Inhibitors
93. Structural Basis for Developing Multitarget Compounds Acting on Cysteinyl Leukotriene Receptor 1 and G-Protein-Coupled Bile Acid Receptor 1
94. Bile acid metabolism and bile acid receptor signaling in metabolic diseases and therapy
95. A nitro-arginine derivative of trimebutine (NO 2-Arg-Trim) attenuates pain induced by colorectal distension in conscious rats
96. SNK @ DANKMEMES: Leveraging Pretrained Embeddings for Multimodal Meme Detection
97. EVALITA Evaluation of NLP and Speech Tools for Italian - December 17th, 2020
98. Epigenetic Modulation by Methionine Deficiency Attenuates the Potential for Gastric Cancer Cell Dissemination
99. Discovery of a AHR pelargonidin agonist that counter-regulates Ace2 expression and attenuates ACE2-SARS-CoV-2 interaction
100. SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts
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