688 results on '"Finck Brian N"'
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52. The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease
53. A dual MTOR/NAD+ acting gerotherapy
54. Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling
55. Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice
56. PPAR/PGC-1 Regulation of Metabolism in Cardiac Disease
57. NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis
58. Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH
59. Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice
60. Inhibiting Monoacylglycerol Acyltransferase 1 Ameliorates Hepatic Metabolic Abnormalities but Not Inflammation and Injury in Mice
61. Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion
62. Lipin 2 Binds Phosphatidic Acid by the Electrostatic Hydrogen Bond Switch Mechanism Independent of Phosphorylation
63. Glucose Transporter 8 (GLUT8) Mediates Fructose-induced de Novo Lipogenesis and Macrosteatosis
64. Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein–Induced Proinflammatory Signaling and Atherosclerosis
65. Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid
66. Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51
67. The mitochondrial pyruvate carrier at the crossroads of intermediary metabolism
68. PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner
69. Association Between Specific Adipose Tissue CD4+ T-Cell Populations and Insulin Resistance in Obese Individuals
70. Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation
71. IRE1α-XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis
72. Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor γ-sparing Thiazolidinedione
73. Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
74. Blocking mitochondrial alanine and pyruvate metabolism in hepatocytes worsens acetaminophen-induced liver injury in mice
75. Metabolic Mechanisms Connecting Alzheimer’s and Parkinson’s Diseases: Potential Avenues for Novel Therapeutic Approaches
76. Mitochondrial Pyruvate Carrier Inhibition Initiates Metabolic Crosstalk to Stimulate Branched Chain Amino Acid Catabolism
77. Something to mTORC About in NASH
78. ChREBP refines the hepatic response to fructose to protect the liver from injury
79. FGF21 Induces PGC-1α and Regulates Carbohydrate and Fatty Acid Metabolism during the Adaptive Starvation Response
80. Chronic Inhibition of Pyruvate Dehydrogenase in Heart Triggers an Adaptive Metabolic Response
81. Dual function lipin proteins and glycerolipid metabolism
82. mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway
83. Cardiac lipin 1 expression is regulated by the peroxisome proliferator activated receptor γ coactivator 1α/estrogen related receptor axis
84. Driving arginine catabolism to activate systemic autophagy
85. Monoacylglycerol O-acyltransferase 1 is required for adipocyte differentiation in vitro but does not affect adiposity in mice
86. Identification of Novel Mitochondrial Pyruvate Carrier Inhibitors by Homology Modeling and Pharmacophore-Based Virtual Screening
87. A Role for Impaired RECK Activity in Metabolic Dysfunction-associated Steatotic Liver Disease
88. Peroxisome Proliferator-activated Receptor-γ Coactivator-1α (PGC-1α) Stimulates VLDL Assembly through Activation of Cell Death-inducing DFFA-like Effector B (CideB)
89. Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice
90. Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor
91. Dietary Fat and Carbohydrates Differentially Alter Insulin Sensitivity During Caloric Restriction
92. Lipin 2 Is a Liver-enriched Phosphatidate Phosphohydrolase Enzyme That Is Dynamically Regulated by Fasting and Obesity in Mice
93. Mechanisms of nonalcoholic steatohepatitis-associated cardiomyopathy: key roles for liver–heart crosstalk.
94. Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
95. Progenitor-intrinsic Metabolic Sensing Promotes Hematopoietic Homeostasis
96. Head Over Hepatocytes for FGF21
97. Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
98. 213-LB: Mechanisms of Metabolic Cross Talk between Mitochondrial Pyruvate Carrier Inhibition and Branched-Chain Amino Acid Catabolism in Hepatocytes
99. Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations
100. Hepatocyte Period 1dictates oxidative substrate selection independent of the core circadian clock
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