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60. 93rd annual convention podium and poster abstracts

Author

Davis, C. M., Strong, S. A., Hellinger, M. D., Williamson, P. R., Larach, S. W., Ferrara, A., Blake, T. B., Medich, D. S., Ziv, Y., Oakley, J. R., Reissman, P., Piccirillo, M., Ulrich, A., Nogueras, J. J., Wexner, S. D., Rubin, M. S., Bodenstein, L. E., Kent, K. C., Williamson, M. E. R., Lewis, W. G., Sagar, P. M., Holdsworth, P. J., Johnston, D., Fazio, V. W., Goldblum, J. R., Sirimarco, M. T., Lavery, I. C., Petras, R. E., Treem, W. R., Cohen, J., Davis, P. M., Hyams, J. S., Eu, K. W., Bartolo, D. C. C., Green, J. D., Riether, R. D., Rosen, L., Stasik, J. J., Sheets, J. A., Reed, J., Khubchandani, I. T., Armitage, N. C., Chapman, M., Hardcastle, J. D., Viamonte, M., Plasencia, G., Wiltz, O., Jacobs, M., Finan, P. J., Passaro, M., Church, J. M., McGannon, E., Wilson, M., Hull-Boiner, S., Kollmorgen, C. F., Meagher, A. P., Wolff, B. G., Pemberton, J. H., Martenson, J. A., Ilstrup, D. M., Moran, M. R., Ramos, A., Rothenberger, D. A., Goldberg, S. M., Johnson, D., Madoff, R. D., Wong, W. D., Finne, III, C. O., Konishi, F., Furuta, K., Kanazawa, K., Lockhart, D., Schmitt, S., Caushaj, P. P., Garcia-Aguilar, J., Belmonte, C., Schiesel, E. C., Mazier, W. P., Senagore, A. J., Piccirillo, M. F., Teoh, T. -A., Yoon, K. -S., Paul, R. A. Patino, Lucas, J., Nelson, R., Norton, N., Cautley, E., Schouten, W. R., Briel, J. W., Auwerda, J. J. A., de Graaf, E. J. R., Lowry, A. C., Sentovich, S. M., Blatchford, G. J., Rivela, L. J., Thorson, A. G., Christensen, M. A., Jorge, J. M. N., Yang, Y. K., Shafik, A., Allendorf, J. D. F., Kayton, M. L., Libutti, S. K., Trokel, M. J., Whelan, R. L., Treat, M. R., Nowygrod, R., Bessler, M., Frank, R. E., Saclarides, T. J., Leurgans, S., Speziale, N. J., Drab, E., Rubin, D., Hull, T. L., Schroeder, T. K., Scholefield, J. H., Ogunbiyi, O. A., Smith, J. H. F., Rogers, K., Sharp, F., Longo, W. E., Vernava, III, A. M., Wade, T. P., Coplin, M. A., Virgo, K. S., Johnson, F. E., Brady, M., Kavolius, J., Quan, S. H. Q., Goldstein, E. T., Feldman, S., Shub, H. A., Bennett, D. R., Kumar, R., McMillen, M. A., Thornton, S., Khoury, D. A., Opelka, F. G., Teoh, T -A., Cohen, S. M., Weiss, E. G., Ortiz, H., De Miguel, M., Armendáriz, P., Rodriguez, J., Chocarro, C., Farouk, R., Dorrance, H. R., Duthie, G. S., Rainey, J. B., Morgado, Jr., P. J., Corman, M. L., Kawamura, Y. J., Sawada, T., Muto, T., Nagai, H., Hill, J., MacLennan, I., Binderow, S. R., Daniel, N., Ehrenpreis, E. D., Jensen, J. E., Bonner, G. F., Ruderman, W. B., Milsom, J. W., Gibbs, D. H., Beck, D. E., Hicks, T. C., Timmcke, A. E., Gathright, Jr, J. B., Cheong, D., Lucas, F. V., McGinity, M., Taylor, B. A., Godwin, P., Holdsworth, P., Lewis, W., Quirke, P., Williamson, M., Kokoszka, J., Pavel, D., Abcarian, H., Stephenson, B. M., Morgan, A. R., Salaman, J. R., Wheeler, M. H., Tran, T. C. K., Willemsen, W., Kuijpers, H. C., Lehman, J. F., Wiseman, J. S., MacFie, J., Sedman, P., May, J., Mancey-Jones, B., Johnstone, D., Nwariaku, F. E., Rochon, R. B., Huber, P. J., Carrico, C. J., Ortega, A., Beart, R., Winchester, D., Steele, G., Green, R., Caushaj, P. F., Devereaux, D., Griffey, S., Reiver, D., Kmiot, W. A., Baker, R., Luchtefeld, M. A., Anthone, G., Schlinkert, R., Roig, J. V., Villoslada, C., Solana, A., Alos, R., Hinojosa, J., Lledo, S., Johnson, D. R. E., Buie, W. D., Jensen, L. L., Heine, J., Hoffmann, B., Timmcke, A., Hicks, T., Opelka, F., Beck, D., Sousa, Jr., A., AraÚjo, S. A., Damico, F. M., Cordeiro, A. C., Pinotti, H. W., Gama, A. H., Fengler, S., Pearl, R., Orsay, C., Seow-Choen, F., Ho, J. M. S., Wiltz, O. H., Torregrosa, M., Brasch, R. C., Bufo, A. J., Krienberg, P., Johnson, G. P., Gowen, G. F., Mullen, P. D., Behrens, D., Hughes, T. G., Wynn, M., Pollack, J. S., Rajagopal, A. S., Huynh, T., Schanbacher, C., Hickson, W. G. E., Yang, Y. -K., Heymen, S., Choi, S. -K., Teoh, T. -A., Wexner, S. D., Vaccaro, C. A., Teoh, T. A., Nogueras, J. J., Choi, S. K., Cheong, D. M. O., Salanga, V. D., MacDonald, A., Baxter, J. N., Finlay, I. G., Mellgren, A., Bremmer, S., Dolk, A., Gillgren, P., Johansson, C., Ahlbäck, S. O., Udén, R., Holmström, B., Ferrara, A., O'Donovan, S., Larach, S. W., Williamson, P. R., Neto, J. A. Reis, Ciquini, S., Quilici, F. A., Reis, Jr., J. A., Torrabadella, L., Salgado, G., Whelan, R. L., Horvath, K. D., Golub, R., Ahsan, H., Cirocco, W., Ziv, Y., Fazio, V. W., Oakley, J. R., Church, J. M., Milsom, J. W., Lavery, L. C., Cohen, S. M., Kmiot, W. A., Reiver, D., Reissman, P., Weiss, E. G., Alós, R., García-Granero, E., Roig, J. V., Uribe, N., Sala, C., Lledo, S., Ozuner, G., Strong, S. A., Bufo, A. J., Daniels, G., Lieberman, R. C., Feldman, S., Lucas, F. V., Longo, W. E., Polites, G., Deshpande, Y., Vernava, A. M., Niehoff, M., Chandel, B., Berglund, D. D., Madoff, R. D., Gemlo, B. T., Spencer, M. P., Goldberg, S. M., Lowry, A. C., Marcello, P. W., Roberts, P. L., Schoetz, D. J., Murray, J. J., Coller, J. A., Veidenheimer, M. C., Koltun, W. A., Bloomer, M. M., Colony, P., Ruggeiro, F., Fleshner, P. R., Michelassi, F., Lewis, W., Williamson, M., Holdsworth, P., Finan, P., Ash, D., Johnston, D., Moran, M. R., Ramos, A., Rothenberger, D. A., Antonenko, D. R., Khanduja, K. S., Fitzgerald, S. D., Meagher, A. P., Moniz-Pereira, P., Wolff, B. G., Outwater, E. K., Marks, G. J., Mohiuddin, M., Sagar, P. M., Hartley, M. N., Mancey-Jones, B., Sedman, P., May, J., MacFie, J., Holbrook, R. F., Rodriguez-Bigas, M. A., Ramakrishnan, K., Palmer, M. L., Petrelli, N. J., Takahashi, T., Nivatvongs, S., Batts, K. P., Lucas, S. W., Klein, S. N., Keidan, R. D., Bannon, J. P., Zhou, J., Armitage, N. C., Hunt, L. M., Robinson, M. H., Hugkulstone, C. E., Clarke, B., Vernon, S. A., Gregson, R. H., Hardcastle, J. D., Ryan, M., Dutta, S., Levine, A., Ortega, A., Anthone, G., Beart, R., Dominguez, J. M., Saclarides, T. J., Bolan, P., Bines, S. D., Adachi, M., Watanabe, T., Sawada, T., Okinaga, K., Muto, T., Hase, K., Shatney, C., Mochizuki, H., Johnson, D., Ure, T., Dehghan, K., Andrus, C. A., Daniel, G. L., D'Emilia, J. C., Rodriguez-Bigas, M., Suh, O. K., Brewer, D. A., Fung, C., Chapuis, P., Bokey, E. L., Garcia, J. C., Banerjee, S., Remzi, F. H., Lavery, I. C., Jorge, J. M. N., Ger, G. C., Gonzalez, L., Gee, A. S., Roe, A. M., Durdey, P., Kaye, M. D., Kyzer, S., Gordon, P. H., Hasegawa, M., Bun, P. Tae, Ikeuchi, D., Onodera, H., Imamura, M., Maetani, S., Blake, T., Hellinger, M., Grewal, H., Klimstra, D. S., Cohen, A. M., Guillem, J. G., Rooney, P. S., Gifford, K. -A., Clarke, P. A., Kuhn, J. A., Bryce, K., Frank, N., Dignan, R. D., Lichliter, W. E., Franko, E., Jacobson, R. M., Preskitt, J. T., Lieberman, Z., Tulanon, P., Steinbach, H., McCarty, T., Simons, T., Plasencia, G., Viamonte, M., Wiltz, O., Jacobs, M., Chen, W. S., Leu, S. Y., Hsu, H., Bessler, M., Halverson, A., Kayton, M. L., Treat, M. R., Nowygrod, R., Congilosi, S., Madoff, R., Wong, W. D., Rothenberger, D., Buie, W. D., Paterson, R., Cartmill, J. A., Trokel, M. J., Gingold, B. S., Cooper, M., Gorfine, S. R., Bauer, J. J., Gelernt, I. M., Kreel, I., Harris, M. T., Vallejo, J. F., Kestenberg, A., Miyajima, N., Kano, N., Ishikawa, Y., Sakai, S., Yamakawa, T., Otchy, D. P., Van Heerden, J. A., Ilstrup, D. M., Weaver, A. L., Winter, L. D., Mav, J., Lee, P. Y., Vetto, J. T., Sullivan, E. S., Rabkin, J., Mayoral, J. L., Matas, A. J., Bove, P., Visser, T., Barkel, D., Villalba, M., Bendick, P., Glover, J., Golub, R. W., Cirocco, W. C., Daniel, N., Altringer, W., Domingues, J. M., Brubaker, L. T., Smith, C. S., Kumar, S., and Gilbert, P.

Published
1994
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61. Podium presentations

Author

Foley, E. F., Marcello, P. W., Roberts, P. L., Murray, J. J., Coller, J. A., Veidenheimer, M. C., Schoetz, D. J., McIntyre, P. B., Pemberton, J. H., Wolff, B. G., Beart, Jr., R. W., Kelly, K. A., Dozois, R. R., Sugita, A., Fukushima, T., Harada, H., Yamamoto, M., Shimada, H., Tjandra, J. J., Fazio, V. W., Milson, J. W., Lavery, I. C., Oakley, J. R., Fabre, J. M., Karch, L. A., Bauer, J. J., Gorfine, S. R., Gelernt, I. M., Metcalf, A. M., Varilek, G., Keck, J. O., Hoffmann, D. C., Sgambati, S. A., Sardella, W. V., Marts, B. C., Longo, W. E., Vernava, III, A. M., Kennedy, D. J., Daniel, G. L., Jones, I., Venkatesh, K. S., Diamond, L. W., Larson, D. M., Ramanujam, P. J., Hicks, J. R., Ellis, C. N., Blakemore, W. S., Nathanson, S. D., Linden, M. D., Tender, P., Zarbo, R. J., Nelson, L., Bannon, J., Marks, G., Zhou, J., Mohiuddin, M., Marks, J., Pollard, C. W., Nivatvongs, S., Rojanasakul, A., Ilstrup, D. M., Speziale, N. J., Saclarides, T. J., Rubin, D. B., Szeluga, D. J., Morgado, P. J., Gomez, L. G., Morgado, Jr., P. J., Neto, J. A. Reis, Quilici, F. A., Cordeiro, F., Reis, Jr., J. A., Nitecki, S., Benn, P., Sarr, M. G., Weiland, L. H., Elhadad, A., Rouffet, F., Baillet, P., Akasu, T., Moriya, Y., Hojo, K., Sugihara, K., Oshima, H., Liu, S. K., Church, J. M., Kirkpatrick, J. R., Danielson, C. L., Dominguez, J. M., Jakate, S. M., Savin, M. H., Altringer, W. J., Lee, C. S., Spencer, M. P., Madoff, R. D., Barrett, R. C., Oster, M. A., Durdey, P., Stein, B. L., Staniunas, R. J., Grewal, H., Guillem, J. G., Quan, S., Enker, W. E., Cohen, A. M., van Tets, W. F., Kuijpers, H. C., Kerner, B. A., Wise, Jr., W. E., Golub, R. W., Arnold, M. W., Aguilar, P. S., Pernikoff, B. J., Eisenstat, T. E., Rubin, R. J., Oliver, G. C., Salvati, E. P., Lunniss, P. J., Sultan, A. H., Barker, P. G., Armstrong, P., Bartram, C. I., Phillips, R. K. S., Schouten, W. R., Briel, J. W., Auwerda, J. J. A., Harnsberger, J. R., Robbins, P. L., Brabbee, G. W., Ryhammer, A. M., Bek, K. M., Hanberg-Sørensen, F., Laurberg, S., Hoff, S. D., Bailey, H. R., Butts, D. R., Max, E., Smith, K. W., Zamora, L. F., Skakun, G. B., Khanduja, K. S., Lee, H., Beart, R. W., Spencer, R., Wiseman, J. S., Senagore, A. J., Bain, I. M., Oliff, J., Min, L., Neoptolomos, J., Keighley, M. R. B., O'Kelly, T. J., Davies, J., Brading, A. F., Mortensen, N. J. McC, Park, J. -G., Han, H. J., Kang, M. S., Nakamura, Y., Goldberg, G. S., Orkin, B. A., Smith, L. E., Fleshner, P. R., Freilich, M. I., Meagher, A. P., Adams, W. J., Lubowski, D. Z., King, D. W., Moran, M., Opelka, F., Timmcke, A., Hicks, T., Gathright, Jr., J. B., Leu, S. Y., Hsu, H., Dean, P. A., Ramsey, P. S., Nelson, H., Philpott, G., Siegel, B., Schwarz, S., Fleshman, J., Welch, M., Connett, J., Buie, W. D., Johnson, D. R., Heine, J. A., Wong, W. D., Rothenberger, D. A., Goldberg, S. M., Shafik, A., MacDonald, A., Craig, J. W., Finlay, I. G., Baxter, J. N., Muir, T. C., Parikh, S., Gold, R. P., Gottesman, L., Annibali, R., Öresland, T., Hallgren, T., Fasth, S., Hultén, L., Farouk, R., Duthie, G. S., MacGregor, A. B., Bartolo, D. C. C., Williamson, M. E. R., Lewis, W. G., Holdsworth, P. J., Hall, N., Finan, P. J., Johnston, D., Seow-Choen, F., Goh, H. S., Motson, R. W., Walsh, C. J., Mooney, E., Yamashita, H. J., Wise, W. E., Hartmann, R. F., Seccia, M., Menconi, C., Ghiselli, G., Cavina, E., Salomon, M. C., Ferrara, A., Larach, S. W., Williamson, P. R., Bass, E. M., Orsay, C. P., Firfer, B., Ramakrishnan, V., Abcarian, H., Bufo, A. J., Feldman, S., Daniels, G. A., Lieberman, R. C., Loder, P. B., Kamm, M. A., Nicholls, R. J., Kum, C. K., Ngoi, S. S., Goh, P. M. Y., Tekant, Y., Isaac, J. R., Gerstle, J. T., Kauffman, G. L., and Koltun, W. A.

Published
1993
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76. Improving outcome prediction in individuals with colorectal cancer and diabetes by accurate assessment of vascular complications: Implications for clinical practice.

Author

Birch, Rebecca J., Downing, Amy, Finan, Paul J., Howell, Simon, Ajjan, Ramzi A., and Morris, Eva J.A.

Subjects
COLORECTAL cancer, DIABETES complications, DIABETES, CLINICAL prediction rules, PEOPLE with diabetes, PROCTOLOGY
Abstract

Diabetes is considered a risk factor for mortality following a diagnosis of cancer. We hypothesised that the risk will vary due to the heterogeneous nature of the population and accurate classification of vascular complications will improve prediction of clinical outcomes. The COloRECTal cancer data Repository (CORECT-R) was used to identify individuals with primary colorectal cancer, who underwent surgical resection in England (2005–2016). Diabetes was recorded using ICD10 codes (E10-E14) during inpatient hospital admission in the six years preceding cancer diagnosis, complication status was determined using the adapted Diabetes Complications Severity Index (aDCSI). Survival and post-operative outcomes were compared between groups. Of 232,367 individuals, 28,642 (12.3%) were recorded as having diabetes, 49.2% of whom had complications according to the aDCSI. Patients with diabetes complications had increased incidence of adverse post-operative outcomes (90-day post-operative mortality (6.6% versus 3.2%) and death during the surgical episode (7.9% versus 3.6%)), compared to those without diabetes. Those without complications had rates comparable to the population without diabetes. The odds of death within a year of diagnosis were higher for those with complicated diabetes compared to those without diabetes [OR 1.58 (95%CI 1.51–1.66) p < 0.01], but no difference was observed between those with uncomplicated diabetes and those without diabetes [OR 1.05 (95%CI 0.99–1.11) p = 0.10]. Prediction of outcome following surgery in colorectal cancer patients with diabetes relies on the accurate assessment of complications. This study suggests that the poor post-operative outcomes in diabetes patients may be associated with diabetes complication rather than diabetes itself. [ABSTRACT FROM AUTHOR]

Published
2021
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81. Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study

Author

Morris, Eva J A, Goldacre, Raphael, Spata, Enti, Mafham, Marion, Finan, Paul J, Shelton, Jon, Richards, Mike, Spencer, Katie, Emberson, Jonathan, Hollings, Sam, Curnow, Paula, Gair, Dominic, Sebag-Montefiore, David, Cunningham, Chris, Rutter, Matthew D, Nicholson, Brian D, Rashbass, Jem, Landray, Martin, Collins, Rory, Casadei, Barbara, and Baigent, Colin

Abstract

There are concerns that the COVID-19 pandemic has had a negative effect on cancer care but there is little direct evidence to quantify any effect. This study aims to investigate the impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England.

Published
2021
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82. Pseudo-Obstruction

Author

Finan, P. J., Stewart, J., and Brennan, T. G.

Published
1986

83. Changes in Drinking Contexts over the Night Course: Concurrent and Lagged Associations with Adolescents’ Nightly Alcohol Use

Author

Finan, Laura J. and Lipperman‐Kreda, Sharon

Abstract

Examining underage drinking contexts can advance the field of adolescent substance use prevention by supporting and informing interventions that can target adolescents in specific contexts. The current study examines how concurrent and lagged situational (i.e., alcohol availability and adult supervision), social (i.e., the number of people and presence of friends), and location (i.e., home vs other location) context characteristics change risks for alcohol use over the night course. Text messages with links to online surveys were used to collect ecological momentary assessment (EMA) data over 2 weekends from adolescents in California. Data were collected using adolescents’ personal cell phones early and late in the evening and the following morning. Analyses were limited to adolescents with at least 1 drinking occasion during EMA (N= 58; Mage = 16.64, SD = 0.74; 48% female; 83% White). Drinking earlier in the evening was positively associated with continued drinking over the night course. Context characteristics were found to play important concurrent and lagged roles in increasing the likelihood of alcohol use over evening hours. Findings indicated substantive concurrent and lagged social, situational, and location‐based contextual effects on adolescent alcohol use over the course of an evening. Importantly, context characteristics were differentially associated with alcohol use over the course of the evening. The fact that these contextual factors are modifiable suggests that the use of prevention strategies delivered to adolescents throughout the evening may reduce adolescents’ drinking and related problems over the evening hours. We examined how concurrent and lagged context characteristics change risks for alcohol use among adolescents over the night course. Using an ecological momentary assessment data, results show that situational (i.e., alcohol availability and adult supervision), social (i.e., the number of people and presence of friends), and location (i.e., home settings) context characteristics change risks for adolescents’ nighttime alcohol use. Results suggest that the use of prevention strategies delivered throughout the evening hours may reduce adolescents’ drinking and related problems.

Published
2020
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84. Alcohol Marketing and Adolescent and Young Adult Alcohol Use Behaviors: A Systematic Review of Cross-Sectional Studies

Author

Finan, Laura J., Lipperman-Kreda, Sharon, Grube, Joel W., Balassone, Anna, and Kaner, Emily

Abstract

Objective:This article provides a systematic review of cross-sectional research examining associations between exposure to alcohol marketing and alcohol use behaviors among adolescents and young adults.Method:Literature searches of eight electronic databases were carried out in February 2017. Searches were not limited by date, language, country, or peer-review status. After abstract and full-text screening for eligibility and study quality, 38 studies that examined the relationship between alcohol marketing and alcohol use behaviors were selected for inclusion.Results:Across alcohol use outcomes, various types of marketing exposure, and different media sources, our findings suggest that cross-sectional evidence indicating a positive relationship between alcohol marketing exposure and alcohol use behaviors among adolescents and young adults was greater than negative or null evidence. In other words, cross-sectional evidence supported that alcohol marketing exposure was associated with young peoples’ alcohol use behaviors. In general, relationships for alcohol promotion (e.g., alcohol-sponsored events) and owning alcohol-related merchandise exposures were more consistently positive than for other advertising exposures. These positive associations were observed across the past four decades, in countries across continents, and with small and large samples.Conclusions:Despite issues of measurement and construct clarity within this body of literature, this review suggests that exposure to alcohol industry marketing may be important for understanding and reducing young peoples’ alcohol use behavior. Future policies aimed at regulating alcohol marketing to a greater extent may have important short- and long-term public health implications for reducing underage or problematic alcohol use among youth.

Published
2020
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85. GAstro-Intestinal

Author

Paterson, I. S., Watson, R. J., Davies, M., England, P. C., Egleston, C. V., Woods, A. E., Gorey, T. F., McGovern, E. M., MacDonald, A., Baxter, J. N., Bessent, R. G., Gray, H. W., Finlay, I. G., O’Donoghue, J. M., Doyle, J., Flynn, J. R., Connolly, K., Gallagher, M., Butler, P., Salman, S., Leahy, A., Keeling, P., Winslet, M. C., Mohsen, Y., Hallissey, M., Fielding, J. W. L., Griffith, J., Adams, I., Sue-Ling, H., Finan, P. J., McMahon, M. J., and Johnston, D.

Published
1992
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86. Colorectal II

Author

Ireland, A., Murphy, D., O’Sullivan, G., Deans, G. T., Heatley, M., Williamson, K., Hamilton, P., Parks, T. G., Rowlands, B. J., Spence, R. A. J., Joyce, W. P., McNicholls, M., McErlean, D., Hyland, J., Hall, N. R., Lewis, W. G., Stephenson, B. M., Mavor, A. I., Finan, P. J., Horgan, A. F., Coulter, J., Molloy, R. G., Sheehan, M., Kirwan, W. O., Campbell, W. J., Nevin, N. C., Hughes, A. E., Ramesh, S., and Galland, R. B.

Published
1992
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87. Colorectal

Author

Williams, N. N., Bennett, M., Tighe, O., Mulcahy, H., O’Donoghue, D., Bouchier-Hayes, D., Croke, D. T., Burke, P., Mealy, K., Gillen, P., Joyce, L., Traynor, O., Hyland, J., Byrne, D. J., Lavelle-Jones, M., Pringle, R., Kuzu, A., Lewis, W. G., Jones, D., Holdsworth, P. J., Finan, P. J., Johnston, D., Morgan, A. R., and Wastell, C.

Published
1992
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88. Research II

Author

Dorudi, S., Sheffield, J. P., Poulsom, R., Northover, J. M. A., Hart, I. R., Lewis, W. G., Holdsworth, P. J., Kuzu, A., Finan, P. J., Johnston, D., Browell, D. A., Kirby, J. A., Gilmore, K., Shenton, B. K., Lennard, T. W. J., Boom, S. J., Zhang, P., Davidson, J. A. H., Ramsay, G., Murchan, P. M., Petsikas, D., Cziperle, D., Greisler, H., Baker, W. H., Mooney, E. F., Guillou, P. J., Monson, J. R. T., O’Donohoe, M. K., Feely, J., and Feeley, T. M.

Published
1992
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89. Variation in the Use of Resection for Colorectal Cancer Liver Metastases.

Author

Fenton, Hayley M., Taylor, John C., Lodge, J. Peter A., Toogood, Giles J., Finan, Paul J., Young, Alastair L., and Morris, Eva J. A.

Abstract

Objective: The aim of this study was to investigate variation in the frequency of resections for colorectal cancer liver metastases across the English NHS. Background: Previous research has shown significant variation in access to liver resection surgery across the English NHS. This study uses more recent data to identify whether inequalities in access to liver resection still persist. Methods: All adults who underwent a major resection for colorectal cancer in an NHS hospital between 2005 and 2012 were identified in the COloRECTal cancer data Repository (CORECT-R). All episodes of care, occurring within 3 years of the initial bowel operation, corresponding to liver resection were identified. Result: During the study period 157,383 patients were identified as undergoing major resection for a colorectal tumor, of whom 7423 (4.7%) underwent ≥1 liver resections. The resection rate increased from 4.1% in 2005, reaching a plateau around 5% by 2012. There was significant variation in the rate of liver resection across hospitals (2.1%-12.2%). Patients with synchronous metastases who have their primary colorectal resection in a hospital with an onsite specialist hepatobiliary team were more likely to receive a liver resection (odds ratio 1.22; 95% confidence interval, 1.10-1.35) than those treated in one without. This effect was absent in resection for metachronous metastases. Conclusions: This study presents the largest reported population-based analysis of liver resection rates in colorectal cancer patients. Significant variation has been observed in patient and hospital characteristics and the likelihood of patients receiving a liver resection, with the data showing that proximity to a liver resection service is as important a factor as deprivation. [ABSTRACT FROM AUTHOR]

Published
2019
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90. Rectal cancer in old age –is it appropriately managed? Evidence from population-based analysis of routine data across the English national health service.

Author

Birch, Rebecca J., Taylor, John C., Downing, Amy, Spencer, Katie, Finan, Paul J., Audisio, Riccardo A., Carrigan, Christopher M., Selby, Peter J., and Morris, Eva J.A.

Subjects
RECTAL cancer, NATIONAL health services, OLD age, ESOPHAGECTOMY, DATA analysis, THERAPEUTICS
Abstract

There is significant debate as to where to draw the line between undertreating older rectal cancer patients and minimising treatment risks. This study sought to examine the use of radical rectal cancer treatments and associated outcomes in relation to age across the English NHS. Patient, tumour and treatment characteristics for all patients diagnosed with a first primary rectal cancer in England between 1st April 2009 and 31st December 2014 were obtained from the CORECT-R data repository. Descriptive analyses and adjusted logistic regression models were undertaken to examine any association between age and the use of major resection and post-surgical outcomes. Funnel plots were used to show variation in adjusted rates of major resection. The proportion of patients who underwent a major surgical resection fell from 66.5% to 31.7%, amongst those aged <70 and aged ≥80 respectively. After adjustment, 30-day post-operative mortality, failure to rescue and prolonged length of stay were significantly higher among the oldest group when compared to the youngest. Patient reported outcomes were not significantly worse amongst older patients. Significant variation was observed in adjusted surgical resection rates in the oldest patients between NHS Trusts. The probability of death due to cancer was comparable across all age groups. Older patients who are selected for surgery have good outcomes, often comparable to their younger counterparts. Significant variation in the treatment of older patients could not be explained by differences in measured characteristics and required further investigation. [ABSTRACT FROM AUTHOR]

Published
2019
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93. Book reviews

Author

de Souza, Anthony R., Greenberg, Michael R., Liu, Ben-chieh, Krotki, Karol J., Marston, Sallie A., Dutt, Ashok K., Lee, Yuk, Batten, David F., Finan, Timothy J., Holmes, J. H., Barr, Brenton M., Domanski, Ryszard, Lawson, Victoria A., Hanink, Dean M., Ray, Clarence G., Mohammad, Saleem, Weaver, Clyde, Caves, Richard E., Suarez-Villa, Luis, Forbes, Dean, Moscove, Brenda J., Pederson, Leland R., Masih, Nolin, Reiner, Thomas A., Uri, Noel D., Jumper, Sidney R., Schmidt, Charles G., Parsons, James J., Peach, James T., McTaggart, W. Donald, Fairbanks, Daniel J., Evans, Peggy, and Platt, Rutherford H.

Published
1987
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94. Participatory diagnosis to identify health problems in a socially vulnerable community.

Author

de Sousa, Izautina Vasconcelos, Brasil, Christina César Praça, da Silva, Raimunda Magalhães, Paixão e Vasconcelos, Dayse, Silva, Kellyanne Abreu, Bezerra, Ilana Nogueira, and Finan, Timoty J.

Subjects
HEALTH promotion, PUBLIC health, SOCIAL conditions in Brazil, MASS mobilization, PUBLIC safety
Abstract

The Health Promotion paradigm led to the acknowledgment of health due to factors linked to the social, political and economic contexts. In Brazil, health inequities are one of the most striking features of the health situation, challenging the effectiveness of intersectoral policies. This study aimed to understand the perception of socially vulnerable community dwellers of the problems that interfere with the health conditions and the coping strategies used. The methodology consisted of a participatory research based on the participatory diagnosis conducted with 31 key informants from the community studied in Fortaleza, Ceará, Brazil. As a result, participants evidenced that the community has health issues due to weak intersectoral actions (infrastructure, public safety, basic sanitation, garbage collection, among others) and that they seek to address them through social mobilization actions and institutional support. Thus, Participatory Diagnosis is thought to increase social involvement with health promotion and problem solving and contributes to ensuring the right to the city to all its residents. [ABSTRACT FROM AUTHOR]

Published
2017
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95. Tobacco outlet density and adolescents’ cigarette smoking: a meta-analysis

Author

Finan, Laura J, Lipperman-Kreda, Sharon, Abadi, Melissa, Grube, Joel W, Kaner, Emily, Balassone, Anna, and Gaidus, Andrew

Abstract

ObjectiveWe conducted meta-analyses of studies that investigated the associations between tobacco outlet density around homes and schools and adolescents’ past-month cigarette smoking.Data sourcesSystematic literature searches of eight databases were carried out in February 2017. Searches were not limited by date, language, country or peer-reviewed status.Study selectionAfter screening for quality, studies that examined the relationship between tobacco outlet density and adolescents’ past-month smoking were selected for inclusion.Data extractionTwo investigators screened study abstracts and full texts and independently extracted data. Consensus was reached at each stage.Data synthesisRandom-effects meta-analyses were conducted on 11 studies that provided 13 effect sizes. Results showed that there was a significant association between tobacco outlet density around homes and adolescents’ past-month smoking behaviour, with an overall effect size of OR=1.08 (95% CI 1.04 to 1.13; P<0.001; I2=0%). For density around schools, the association was not statistically significant (OR=1.01, 95% CI 0.98 to 1.03; P=0.53; I2=39%).ConclusionsThese findings suggest that exposure to tobacco outlets near home environments may be important for understanding adolescents’ past-month smoking. Restricting access to tobacco outlets and controlling the number of outlets in residential areas may be an effective preventive strategy to help reduce adolescents’ smoking.

Published
2019
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98. A retrospective observational study examining the characteristics and outcomes of tumours diagnosed within and without of the English NHS Bowel Cancer Screening Programme

Author

Morris, E J A, primary, Whitehouse, L E, additional, Farrell, T, additional, Nickerson, C, additional, Thomas, J D, additional, Quirke, P, additional, Rutter, M D, additional, Rees, C, additional, Finan, P J, additional, Wilkinson, J R, additional, and Patnick, J, additional

Published
2012
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99. High hospital research participation and improved colorectal cancer survival outcomes: a population-based study

Author

Downing, Amy, Morris, Eva JA, Corrigan, Neil, Sebag-Montefiore, David, Finan, Paul J, Thomas, James D, Chapman, Michael, Hamilton, Russell, Campbell, Helen, Cameron, David, Kaplan, Richard, Parmar, Mahesh, Stephens, Richard, Seymour, Matt, Gregory, Walter, and Selby, Peter

Abstract

ObjectiveIn 2001, the National Institute for Health Research Cancer Research Network (NCRN) was established, leading to a rapid increase in clinical research activity across the English NHS. Using colorectal cancer (CRC) as an example, we test the hypothesis that high, sustained hospital-level participation in interventional clinical trials improves outcomes for all patients with CRC managed in those research-intensive hospitals.DesignData for patients diagnosed with CRC in England in 2001–2008 (n=209 968) were linked with data on accrual to NCRN CRC studies (n=30 998). Hospital Trusts were categorised by the proportion of patients accrued to interventional studies annually. Multivariable models investigated the relationship between 30-day postoperative mortality and 5-year survival and the level and duration of study participation.ResultsMost of the Trusts achieving high participation were district general hospitals and the effects were not limited to cancer ‘centres of excellence’, although such centres do make substantial contributions. Patients treated in Trusts with high research participation (≥16%) in their year of diagnosis had lower postoperative mortality (p<0.001) and improved survival (p<0.001) after adjustment for casemix and hospital-level variables. The effects increased with sustained research participation, with a reduction in postoperative mortality of 1.5% (6.5%–5%, p<2.2×10−6) and an improvement in survival (p<10−19; 5-year difference: 3.8% (41.0%–44.8%)) comparing high participation for ≥4 years with 0 years.ConclusionsThere is a strong independent association between survival and participation in interventional clinical studies for all patients with CRC treated in the hospital study participants. Improvement precedes and increases with the level and years of sustained participation.

Published
2017
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