51. SEOM clinical guidelines for the treatment of anal cancer.
- Author
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Maurel J, Fernández-Martos C, Feliu J, and Isla D
- Subjects
- Antineoplastic Agents pharmacology, Anus Neoplasms complications, Carcinoma complications, Carcinoma therapy, Combined Modality Therapy methods, HIV Infections complications, HIV Infections therapy, Humans, Societies, Medical, Treatment Outcome, Anus Neoplasms therapy, Medical Oncology methods
- Abstract
Anal carcinoma is an uncommon disorder accounting for less than 2% of large bowel malignancies and 1-6% of anorectal tumours. Its incidence ranges between 0.5 and 1% per 100,000. Local staging should be done with MR imaging using an external pelvic phased-array coil. Treatment strategy should be optimally discussed in a multidisciplinary team. HIV-positive patients seem to achieve similar response rate and overall survival to HIV-negative patients but with increased toxicity and higher local recurrences. Combined modality treatment with irradiation and chemotherapy has resulted in complete response over 90% and local control over 85%. This guide gives recommendations for diagnosis, staging and treatment.
- Published
- 2011
- Full Text
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