680 results on '"Fauser B."'
Search Results
52. A prospective randomized comparison of sequential versus monoculture systems for in-vitro human blastocyst development
- Author
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Macklon, N. S., Pieters, M. H.E.C., Hassan, M. A., Jeucken, P. H.M., Eijkemans, M. J.C., and Fauser, B. C.J.M.
- Published
- 2002
53. Conception to ongoing pregnancy: the 'black box' of early pregnancy loss
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Macklon, N. S., Geraedts, J. P.M., and Fauser, B. C.J.M.
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- 2002
54. Residual ovarian activity during oral steroid contraception
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van Heusden, A. M. and Fauser, B. C.J.M.
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- 2002
55. FSH and ovarian response: spontaneous recovery of pituitary–ovarian activity during the pill-free period vs. exogenous recombinant FSH during high-dose combined oral contraceptives
- Author
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van Heusden, A. M, Coelingh Bennink, H. J. T, and Fauser, B. C. J. M
- Published
- 2002
56. Endocrine Profiles after Triggering of Final Oocyte Maturation with GnRH Agonist after Cotreatment with the GnRH Antagonist Ganirelix during Ovarian Hyperstimulation for in Vitro Fertilization
- Author
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Fauser, B. C., de Jong, D., Olivennes, F., Wramsby, H., Tay, C., Itskovitz-Eldor, J., and van Hooren, H. G.
- Published
- 2002
57. Erratum: Letter to the Editor: Individualized FSH dosing improves safety and reduces iatrogenic poor response while maintaining live-birth rates (Hum Reprod (2018) 33 (985-986)
- Author
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La Marca, A., Blockeel, C., Bosch, E., Fanchin, R., Fatemi, H. M., Fauser, B. C., Garcia-Velasco, J. A., Humaidan, P., Tarlatzis, B. C., and Nelson, S. M.
- Published
- 2018
58. Letter to the Editor: Individualized FSH dosing improves safety and reduces iatrogenic poor response while maintaining live-birth rates (vol 33, pg 985, 2018)
- Author
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La Marca A, Blockeel C, Bosch E, Fanchin R, Fatemi H, Fauser B, Garcia-Velasco J, Humaidan P, Tarlatzis B, and Nelson S
- Published
- 2018
59. Individualized FSH dosing improves safety and reduces iatrogenic poor response while maintaining live-birth rates
- Author
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La Marca A, Blockeel C, Bosch E, Fanchin R, Fatemi H, Fauser B, Garcia-Velasco J, Humaidan P, Tarlatzis B, and Nelson S
- Published
- 2018
60. What is the prognosis for a live birth after unexplained recurrent implantation failure following IVF/ICSI?
- Author
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Koot, Y E M, primary, Hviid Saxtorph, M, additional, Goddijn, M, additional, de Bever, S, additional, Eijkemans, M J C, additional, Wely, M v, additional, van der Veen, F, additional, Fauser, B C J M, additional, and Macklon, N S, additional
- Published
- 2019
- Full Text
- View/download PDF
61. Associations of preconception Body Mass Index in women with PCOS and BMI and blood pressure of their offspring
- Author
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Gunning, M. N., primary, van Rijn, B. B., additional, Bekker, M. N., additional, de Wilde, M. A., additional, Eijkemans, M. J. C., additional, and Fauser, B. C. J. M., additional
- Published
- 2019
- Full Text
- View/download PDF
62. Stakeholders views on the ethical aspects of oocyte banking for third-party assisted reproduction: a qualitative interview study with donors, recipients and professionals
- Author
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Kool, E M, primary, van der Graaf, R, additional, Bos, A M E, additional, Pieters, J J P M, additional, Custers, I M, additional, Fauser, B C J M, additional, and Bredenoord, A L, additional
- Published
- 2019
- Full Text
- View/download PDF
63. Ethics of oocyte banking for third-party assisted reproduction : a systematic review
- Author
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Kool, E M, Bos, A M E, van der Graaf, R, Fauser, B C J M, Bredenoord, A L, Kool, E M, Bos, A M E, van der Graaf, R, Fauser, B C J M, and Bredenoord, A L
- Published
- 2018
64. Prevalence of Subclinical Coronary Artery Disease Assessed by Coronary Computed Tomography Angiography in 45- to 55-Year-Old Women With a History of Preeclampsia
- Author
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Zoet, G.A., Benschop, L., Boersma, E., Budde, R.P., Fauser, B., Graaf, Y. van der, Groot, C.J. de, Maas, A.H.E.M., Roeters van Lennep, J.E., Steegers, E.A., Visseren, F.L., Rijn, B.B. van, Velthuis, B.K., Franx, A., Zoet, G.A., Benschop, L., Boersma, E., Budde, R.P., Fauser, B., Graaf, Y. van der, Groot, C.J. de, Maas, A.H.E.M., Roeters van Lennep, J.E., Steegers, E.A., Visseren, F.L., Rijn, B.B. van, Velthuis, B.K., and Franx, A.
- Abstract
Item does not contain fulltext
- Published
- 2018
65. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.
- Author
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Tapanainen J.S., Witchel S., Woolcock J., Yildiz B.O., Rombauts L., Mol B.W., Mansfield D., Joham A., Teede H.J., Misso M.L., Costello M.F., Dokras A., Laven J., Moran L., Piltonen T., Norman R.J., Andersen M., Azziz R., Balen A., Baye E., Boyle J., Brennan L., Broekmans F., Dabadghao P., Devoto L., Dewailly D., Downes L., Fauser B., Franks S., Garad R.M., Gibson-Helm M., Harrison C., Hart R., Hawkes R., Hirschberg A., Hoeger K., Hohmann F., Hohmann H., Vet D., Hutchison S., Johnson L., Jordan C., Kulkarni J., Legro R.S., Li R., Lujan M., Malhotra J., Marsh K., McAllister V., Mocanu E., Ng E., Oberfield S., Ottey S., Pena A., Qiao J., Redman L., Rodgers R., Romualdi D., Shah D., Speight J., Spritzer P.M., Stener-Victorin E., Stepto N., Tassone E.C., Thangaratinam S., Thondan M., Tzeng C.-R., van der Spuy Z., Vanky E., Vogiatzi M., Wan A., Wijeyaratne C., Tapanainen J.S., Witchel S., Woolcock J., Yildiz B.O., Rombauts L., Mol B.W., Mansfield D., Joham A., Teede H.J., Misso M.L., Costello M.F., Dokras A., Laven J., Moran L., Piltonen T., Norman R.J., Andersen M., Azziz R., Balen A., Baye E., Boyle J., Brennan L., Broekmans F., Dabadghao P., Devoto L., Dewailly D., Downes L., Fauser B., Franks S., Garad R.M., Gibson-Helm M., Harrison C., Hart R., Hawkes R., Hirschberg A., Hoeger K., Hohmann F., Hohmann H., Vet D., Hutchison S., Johnson L., Jordan C., Kulkarni J., Legro R.S., Li R., Lujan M., Malhotra J., Marsh K., McAllister V., Mocanu E., Ng E., Oberfield S., Ottey S., Pena A., Qiao J., Redman L., Rodgers R., Romualdi D., Shah D., Speight J., Spritzer P.M., Stener-Victorin E., Stepto N., Tassone E.C., Thangaratinam S., Thondan M., Tzeng C.-R., van der Spuy Z., Vanky E., Vogiatzi M., Wan A., and Wijeyaratne C.
- Abstract
Study Question: What is the recommended assessment and management of women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise, and consumer preference?. Summary Answer: International evidence-based guidelines including 166 recommendations and practice points, addressed prioritized questions to promote consistent, evidence-based care and improve the experience and health outcomes of women with PCOS. What is Known Already: Previous guidelines either lacked rigorous evidence-based processes, did not engage consumer and international multidisciplinary perspectives, or were outdated. Diagnosis of PCOS remains controversial and assessment and management are inconsistent. The needs of women with PCOS are not being adequately met and evidence practice gaps persist. Study Design, Size, Duration: International evidence-based guideline development engaged professional societies and consumer organizations with multidisciplinary experts and women with PCOS directly involved at all stages. Appraisal of Guidelines for Research and Evaluation (AGREE) II-compliant processes were followed, with extensive evidence synthesis. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework was applied across evidence quality, feasibility, acceptability, cost, implementation and ultimately recommendation strength. Participants/Materials, Setting, Methods: Governance included a six continent international advisory and a project board, five guideline development groups (GDGs), and consumer and translation committees. Extensive health professional and consumer engagement informed guideline scope and priorities. Engaged international society-nominated panels included pediatrics, endocrinology, gynecology, primary care, reproductive endocrinology, obstetrics, psychiatry, psychology, dietetics, exercise physiology, public health and other experts, alongside consumers, project management, evidence synthesis, and translation
- Published
- 2018
66. Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome.
- Author
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Malhotra J., Stepto N., Tapanainen J.S., Tassone E.C., Thangaratinam S., Thondan M., Tzeng C.-R., Van Der Spuy Z., Vanky E., Vogiatzi M., Wan A., Wijeyaratne C., Witchel S., Woolcock J., Yildiz B.O., Qiao J., Redman L., Rodgers R., Romualdi D., Shah D., Speight J., Spritzer P.M., Stener-Victorin E., Teede H.J., Rombauts L., Moran L., Mol B.W., Mansfield D., Joham A., Misso M.L., Costello M.F., Dokras A., Laven J., Piltonen T., Norman R.J., Andersen M., Azziz R., Balen A., Baye E., Boyle J., Brennan L., Broekmans F., Dabadghao P., Devoto L., Dewailly D., Downes L., Fauser B., Franks S., Garad R.M., Gibson-Helm M., Harrison C., Hart R., Hawkes R., Hirschberg A., Hoeger K., Hohmann F., Hutchison S., Johnson L., Jordan C., Kulkarni J., Legro R.S., Li R., Lujan M., Marsh K., McAllister V., Mocanu E., Ng E., Oberfield S., Ottey S., Pena A., Malhotra J., Stepto N., Tapanainen J.S., Tassone E.C., Thangaratinam S., Thondan M., Tzeng C.-R., Van Der Spuy Z., Vanky E., Vogiatzi M., Wan A., Wijeyaratne C., Witchel S., Woolcock J., Yildiz B.O., Qiao J., Redman L., Rodgers R., Romualdi D., Shah D., Speight J., Spritzer P.M., Stener-Victorin E., Teede H.J., Rombauts L., Moran L., Mol B.W., Mansfield D., Joham A., Misso M.L., Costello M.F., Dokras A., Laven J., Piltonen T., Norman R.J., Andersen M., Azziz R., Balen A., Baye E., Boyle J., Brennan L., Broekmans F., Dabadghao P., Devoto L., Dewailly D., Downes L., Fauser B., Franks S., Garad R.M., Gibson-Helm M., Harrison C., Hart R., Hawkes R., Hirschberg A., Hoeger K., Hohmann F., Hutchison S., Johnson L., Jordan C., Kulkarni J., Legro R.S., Li R., Lujan M., Marsh K., McAllister V., Mocanu E., Ng E., Oberfield S., Ottey S., and Pena A.
- Abstract
STUDY QUESTION: What is the recommended assessment and management of women with polycystic ovary syndrome (PCOS), based on the best available evidence, clinical expertise and consumer preference? SUMMARY ANSWER: International evidence-based guidelines, including 166 recommendations and practice points, addressed prioritized questions to promote consistent, evidence-based care and improve the experience and health outcomes of women with PCOS. WHAT IS KNOWN ALREADY: Previous guidelines either lacked rigorous evidence-based processes, did not engage consumer and international multidisciplinary perspectives, or were outdated. Diagnosis of PCOS remains controversial, and assessment and management are inconsistent. The needs of women with PCOS are not being adequately met and evidence practice gaps persist. STUDY DESIGN, SIZE, DURATION: International evidence-based guideline development engaged professional societies and consumer organizations with multidisciplinary experts and women with PCOS directly involved at all stages. Appraisal of Guidelines for Research and Evaluation (AGREE) II-compliant processes were followed, with extensive evidence synthesis. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework was applied across evidence quality, feasibility, acceptability, cost, implementation and ultimately recommendation strength. PARTICIPANTS/MATERIALS, SETTING, METHODS: Governance included a six continent international advisory and a project board, five guideline development groups, and consumer and translation committees. Extensive health professional and consumer engagement informed guideline scope and priorities. Engaged international society-nominated panels included pediatrics, endocrinology, gynecology, primary care, reproductive endocrinology, obstetrics, psychiatry, psychology, dietetics, exercise physiology, public health and other experts, alongside consumers, project management, evidence synthesis and translation experts.
- Published
- 2018
67. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
- Author
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Day, F. (Felix), Karaderi, T. (Tugce), Jones, M. R. (Michelle R.), Meun, C. (Cindy), He, C. (Chunyan), Drong, A. (Alex), Kraft, P. (Peter), Lin, N. (Nan), Huang, H. (Hongyan), Broer, L. (Linda), Magi, R. (Reedik), Saxena, R. (Richa), Laisk, T. (Triin), Urbanek, M. (Margrit), Hayes, M. G. (M. Geoffrey), Thorleifsson, G. (Gudmar), Fernandez-Tajes, J. (Juan), Mahajan, A. (Anubha), Mullin, B. H. (Benjamin H.), Stuckey, B. G. (Bronwyn G. A.), Spector, T. D. (Timothy D.), Wilson, S. G. (Scott G.), Goodarzi, M. O. (Mark O.), Davis, L. (Lea), Obermayer-Pietsch, B. (Barbara), Uitterlinden, A. G. (Andre G.), Anttila, V. (Verneri), Neale, B. M. (Benjamin M.), Järvelin, M.-R. (Marjo-Riitta), Fauser, B. (Bart), Kowalska, I. (Irina), Visser, J. A. (Jenny A.), Andersen, M. (Marianne), Ong, K. (Ken), Stener-Victorin, E. (Elisabet), Ehrmann, D. (David), Legro, R. S. (Richard S.), Salumets, A. (Andres), McCarthy, M. I. (Mark I.), Morin-Papunen, L. (Laure), Thorsteinsdottir, U. (Unnur), Stefansson, K. (Kari), Styrkarsdottir, U. (Unnur), Perry, J. R. (John R. B.), Dunaif, A. (Andrea), Laven, J. (Joop), Franks, S. (Steve), Lindgren, C. M. (Cecilia M.), Welt, C. K. (Corrine K.), Day, F. (Felix), Karaderi, T. (Tugce), Jones, M. R. (Michelle R.), Meun, C. (Cindy), He, C. (Chunyan), Drong, A. (Alex), Kraft, P. (Peter), Lin, N. (Nan), Huang, H. (Hongyan), Broer, L. (Linda), Magi, R. (Reedik), Saxena, R. (Richa), Laisk, T. (Triin), Urbanek, M. (Margrit), Hayes, M. G. (M. Geoffrey), Thorleifsson, G. (Gudmar), Fernandez-Tajes, J. (Juan), Mahajan, A. (Anubha), Mullin, B. H. (Benjamin H.), Stuckey, B. G. (Bronwyn G. A.), Spector, T. D. (Timothy D.), Wilson, S. G. (Scott G.), Goodarzi, M. O. (Mark O.), Davis, L. (Lea), Obermayer-Pietsch, B. (Barbara), Uitterlinden, A. G. (Andre G.), Anttila, V. (Verneri), Neale, B. M. (Benjamin M.), Järvelin, M.-R. (Marjo-Riitta), Fauser, B. (Bart), Kowalska, I. (Irina), Visser, J. A. (Jenny A.), Andersen, M. (Marianne), Ong, K. (Ken), Stener-Victorin, E. (Elisabet), Ehrmann, D. (David), Legro, R. S. (Richard S.), Salumets, A. (Andres), McCarthy, M. I. (Mark I.), Morin-Papunen, L. (Laure), Thorsteinsdottir, U. (Unnur), Stefansson, K. (Kari), Styrkarsdottir, U. (Unnur), Perry, J. R. (John R. B.), Dunaif, A. (Andrea), Laven, J. (Joop), Franks, S. (Steve), Lindgren, C. M. (Cecilia M.), and Welt, C. K. (Corrine K.)
- Abstract
Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. PCOS is diagnosed with two different sets of diagnostic criteria, resulting in a phenotypic spectrum of PCOS cases. The genetic similarities between cases diagnosed based on the two criteria have been largely unknown. Previous studies in Chinese and European subjects have identified 16 loci associated with risk of PCOS. We report a fixed-effect, inverse-weighted-variance meta-analysis from 10,074 PCOS cases and 103,164 controls of European ancestry and characterisation of PCOS related traits. We identified 3 novel loci (near PLGRKT, ZBTB16 and MAPRE1), and provide replication of 11 previously reported loci. Only one locus differed significantly in its association by diagnostic criteria; otherwise the genetic architecture was similar between PCOS diagnosed by self-report and PCOS diagnosed by NIH or non-NIH Rotterdam criteria across common variants at 13 loci. Identified variants were associated with hyperandrogenism, gonadotropin regulation and testosterone levels in affected women. Linkage disequilibrium score regression analysis revealed genetic correlations with obesity, fasting insulin, type 2 diabetes, lipid levels and coronary artery disease, indicating shared genetic architecture between metabolic traits and PCOS. Mendelian randomization analyses suggested variants associated with body mass index, fasting insulin, menopause timing, depression and male-pattern balding play a causal role in PCOS. The data thus demonstrate 3 novel loci associated with PCOS and similar genetic architecture for all diagnostic criteria. The data also provide the first genetic evidence for a male phenotype for PCOS and a causal link to depression, a previously hypothesized comorbid disease. Thus, the genetics provi
- Published
- 2018
68. Ethics of oocyte banking for third-party assisted reproduction: a systematic review
- Author
-
Medical Humanities Onderzoek Team 2, MS VPG/Gynaecologie, Child Health, Cancer, Medical Humanities Onderzoek Team 1, Circulatory Health, JC onderzoeksprogramma Methodologie, Brain, Regenerative Medicine and Stem Cells, Kool, E M, Bos, A M E, van der Graaf, R, Fauser, B C J M, Bredenoord, A L, Medical Humanities Onderzoek Team 2, MS VPG/Gynaecologie, Child Health, Cancer, Medical Humanities Onderzoek Team 1, Circulatory Health, JC onderzoeksprogramma Methodologie, Brain, Regenerative Medicine and Stem Cells, Kool, E M, Bos, A M E, van der Graaf, R, Fauser, B C J M, and Bredenoord, A L
- Published
- 2018
69. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria
- Author
-
Day, F, Karaderi, T, Jones, MR, Meun, Cindy, He, CY, Drong, A, Kraft, P, Lin, N, Huang, HY, Broer, Linda, Magi, R, Saxena, R, Laisk, T, Urbanek, M, Hayes, MG, Thorleifsson, G, Fernandez-Tajes, J, Mahajan, A, Mullin, BH, Stuckey, BGA, Spector, TD, Wilson, SG, Goodarzi, MO, Davis, L, Obermayer-Pietsch, B, Uitterlinden, André, Anttila, V, Neale, BM, Jarvelin, MR, Fauser, B, Kowalska, I, Visser, Jenny, Andersen, M, Ong, K, Stener-Victorin, E, Ehrmann, D, Legro, RS, Salumets, A, McCarthy, MI, Morin-Papunen, L, Thorsteinsdottir, U, Stefansson, K, Styrkarsdottir, U, Perry, JRB, Dunaif, A, Laven, Joop, Franks, S, Lindgren, CM, Welt, CK, Day, F, Karaderi, T, Jones, MR, Meun, Cindy, He, CY, Drong, A, Kraft, P, Lin, N, Huang, HY, Broer, Linda, Magi, R, Saxena, R, Laisk, T, Urbanek, M, Hayes, MG, Thorleifsson, G, Fernandez-Tajes, J, Mahajan, A, Mullin, BH, Stuckey, BGA, Spector, TD, Wilson, SG, Goodarzi, MO, Davis, L, Obermayer-Pietsch, B, Uitterlinden, André, Anttila, V, Neale, BM, Jarvelin, MR, Fauser, B, Kowalska, I, Visser, Jenny, Andersen, M, Ong, K, Stener-Victorin, E, Ehrmann, D, Legro, RS, Salumets, A, McCarthy, MI, Morin-Papunen, L, Thorsteinsdottir, U, Stefansson, K, Styrkarsdottir, U, Perry, JRB, Dunaif, A, Laven, Joop, Franks, S, Lindgren, CM, and Welt, CK
- Published
- 2018
70. Genetic studies of body mass index yield new insights for obesity biology
- Author
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Locke, A, Kahali, B, Berndt, S, Justice, A, Pers, T, Day, F, Powell, C, Vedantam, S, Buchkovich, M, Yang, J, Croteau-Chonka, D, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Magi, R, Randall, J, Winkler, T, Wood, A, Workalemahu, T, Faul, J, Smith, J, Zhao, J, Zhao, W, Chen, J, Fehrmann, R, Hedman, A, Karjalainen, J, Schmidt, E, Absher, D, Amin, N, Anderson, D, Beekman, M, Bolton, J, Bragg-Gresham, J, Buyske, S, Demirkan, A, Deng, G, Ehret, G, Feenstra, B, Feitosa, M, Fischer, K, Goel, A, Gong, J, Jackson, A, Kanoni, S, Kleber, M, Kristiansson, K, Lim, U, Lotay, V, Mangino, M, Leach, I, Medina-Gomez, C, Medland, S, Nalls, M, Palmer, C, Pasko, D, Pechlivanis, S, Peters, M, Prokopenko, I, Shungin, D, Stancakova, A, Strawbridge, R, Sung, Y, Tanaka, T, Teumer, A, Trompet, S, van der Laan, S, van Setten, J, Van Vliet-Ostaptchouk, J, Wang, Z, Yengo, L, Zhang, W, Isaacs, A, Albrecht, E, Arnlov, J, Arscott, G, Attwood, A, Bandinelli, S, Barrett, A, Bas, I, Bellis, C, Bennett, A, Berne, C, Blagieva, R, Bluher, M, Bohringer, S, Bonnycastle, L, Bottcher, Y, Boyd, H, Bruinenberg, M, Caspersen, I, Chen, Y, Clarke, R, Daw, E, de Craen, A, Delgado, G, Dimitriou, M, Doney, A, Eklund, N, Estrada, K, Eury, E, Folkersen, L, Fraser, R, Garcia, M, Geller, F, Giedraitis, V, Gigante, B, Go, A, Golay, A, Goodall, A, Gordon, S, Gorski, M, Grabe, H, Grallert, H, Grammer, T, Grassler, J, Gronberg, H, Groves, C, Gusto, G, Haessler, J, Hall, P, Haller, T, Hallmans, G, Hartman, C, Hassinen, M, Hayward, C, Heard-Costa, N, Helmer, Q, Hengstenberg, C, Holmen, O, Hottenga, J, James, A, Jeff, J, Johansson, A, Jolley, J, Juliusdottir, T, Kinnunen, L, Koenig, W, Koskenvuo, M, Kratzer, W, Laitinen, J, Lamina, C, Leander, K, Lee, N, Lichtner, P, Lind, L, Lindstrom, J, Lo, K, Lobbens, S, Lorbeer, R, Lu, Y, Mach, F, Magnusson, P, Mahajan, A, Mcardle, W, Mclachlan, S, Menni, C, Merger, S, Mihailov, E, Milani, L, Moayyeri, A, Monda, K, Morken, M, Mulas, A, Muller, G, Muller-Nurasyid, M, Musk, A, Nagaraja, R, Nothen, M, Nolte, I, Pilz, S, Rayner, N, Renstrom, F, Rettig, R, Ried, J, Ripke, S, Robertson, N, Rose, L, Sanna, S, Scharnagl, H, Scholtens, S, Schumacher, F, Scott, W, Seufferlein, T, Shi, J, Smith, A, Smolonska, J, Stanton, A, Steinthorsdottir, V, Stirrups, K, Stringham, H, Sundstrom, J, Swertz, M, Swift, A, Syvanen, A, Tan, S, Tayo, B, Thorand, B, Thorleifsson, G, Tyrer, J, Uh, H, Vandenput, L, Verhulst, F, Vermeulen, S, Verweij, N, Vonk, J, Waite, L, Warren, H, Waterworth, D, Weedon, M, Wilkens, L, Willenborg, C, Wilsgaard, T, Wojczynski, M, Wong, A, Wright, A, Zhang, Q, Brennan, E, Choi, M, Dastani, Z, Drong, A, Eriksson, P, Franco-Cereceda, A, Gadin, J, Gharavi, A, Goddard, M, Handsaker, R, Huang, J, Karpe, F, Kathiresan, S, Keildson, S, Kiryluk, K, Kubo, M, Lee, J, Liang, L, Lifton, R, Ma, B, Mccarroll, S, Mcknight, A, Min, J, Moffatt, M, Montgomery, G, Murabito, J, Nicholson, G, Nyholt, D, Okada, Y, Perry, J, Dorajoo, R, Reinmaa, E, Salem, R, Sandholm, N, Scott, R, Stolk, L, Takahashi, A, Van't Hooft, F, Vinkhuyzen, A, Westra, H, Zheng, W, Zondervan, K, Heath, A, Arveiler, D, Bakker, S, Beilby, J, Bergman, R, Blangero, J, Bovet, P, Campbell, H, Caulfield, M, Cesana, G, Chakravarti, A, Chasman, D, Chines, P, Collins, F, Crawford, D, Cupples, L, Cusi, D, Danesh, J, de Faire, U, Den Ruijter, H, Dominiczak, A, Erbel, R, Erdmann, J, Eriksson, J, Farrall, M, Felix, S, Ferrannini, E, Ferrieres, J, Ford, I, Forouhi, N, Forrester, T, Franco, O, Gansevoort, R, Gejman, P, Gieger, C, Gottesman, O, Gudnason, V, Gyllensten, U, Hall, A, Harris, T, Hattersley, A, Hicks, A, Hindorff, L, Hingorani, A, Hofman, A, Homuth, G, Hovingh, G, Humphries, S, Hunt, S, Hypponen, E, Illig, T, Jacobs, K, Jarvelin, M, Jockel, K, Johansen, B, Jousilahti, P, Jukema, J, Jula, A, Kaprio, J, Kastelein, J, Keinanen-Kiukaanniemi, S, Kiemeney, L, Knekt, P, Kooner, J, Kooperberg, C, Kovacs, P, Kraja, A, Kumari, M, Kuusisto, J, Lakka, T, Langenberg, C, 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- Abstract
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10-8), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20 % of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
- Published
- 2015
71. Prolonged estrogen deprivation is associated with increased cardiovascular disease risk among women with primary ovarian insufficiency
- Author
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Christ, J., Gunning, M., Palla, G., Eijkemans, R., Lambalk, Cornelis B., Laven, Joop S., and Fauser, B.
- Published
- 2017
72. Ethics of oocyte banking for third-party assisted reproduction: a systematic review
- Author
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Kool, E M, primary, Bos, A M E, additional, van der Graaf, R, additional, Fauser, B C J M, additional, and Bredenoord, A L, additional
- Published
- 2018
- Full Text
- View/download PDF
73. Cardiovascular RiskprofilE - IMaging and gender-specific disOrders (CREw-IMAGO): rationale and design of a multicenter cohort study
- Author
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Zoet, G.A., Meun, C., Benschop, L., Boersma, E., Budde, R.P., Fauser, B., Groot, C.J. de, Lugt, A. van der, Maas, A.H.E.M., Moons, K.G., Lennep, J.E. Roeters van, Roos-Hesselink, J.W., Steegers, E.A., Rijn, B.B. van, Laven, J.S., Franx, A., Velthuis, B.K., Zoet, G.A., Meun, C., Benschop, L., Boersma, E., Budde, R.P., Fauser, B., Groot, C.J. de, Lugt, A. van der, Maas, A.H.E.M., Moons, K.G., Lennep, J.E. Roeters van, Roos-Hesselink, J.W., Steegers, E.A., Rijn, B.B. van, Laven, J.S., Franx, A., and Velthuis, B.K.
- Abstract
Contains fulltext : 176974.pdf (publisher's version ) (Open Access), BACKGROUND: Reproductive disorders, such as polycystic ovary syndrome (PCOS), primary ovarian insufficiency (POI) and hypertensive pregnancy disorders (HPD) like pre-eclampsia (PE), are associated with an increased risk of cardiovascular disease (CVD). Detection of early signs of cardiovascular disease (CVD), as well as identification of risk factors among women of reproductive age which improve cardiovascular risk prediction, is a challenge and current models might underestimate long-term health risks. The aim of this study is to assess cardiovascular disease in patients with a history of a reproductive disorder by low-dose computed tomography (CT). METHODS: Women of 45 - 55 years, who experienced a reproductive disorder (PCOS, POI, HPD), are invited to participate in this multicenter, prospective, cohort study. Women will be recruited after regular cardiovascular screening, including assessment of classical cardiovascular risk factors. CT of the coronary arteries (both coronary artery calcium scoring (CACS), and contrast-enhanced coronary CT angiography (CCTA)) and carotid siphon calcium scoring (CSC) is planned in 300 women with HPD and 300 women with PCOS or POI. In addition, arterial stiffness (non-invasive pulse wave velocity (PWV)) measurement and cell-based biomarkers (inflammatory circulating cells) will be obtained. DISCUSSION: Initial inclusion is focused on women of 45 - 55 years. However, the age range (40 - 45 years and/or >/= 55 years) and group composition may be adjusted based on the findings of the interim analysis. Participants can potentially benefit from information obtained in this study concerning their current cardiovascular health and expected future risk of cardiovascular events. The results of this study will provide insights in the development of CVD in women with a history of reproductive disorders. Ultimately, this study may lead to improved cardiovascular prediction models and will provide an opportunity for timely adjustment of preven
- Published
- 2017
74. Implications of the 2014 Androgen Excess and Polycystic Ovary Syndrome Society guidelines on polycystic ovarian morphology for polycystic ovary syndrome diagnosis
- Author
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Christ, J. P., Gunning, M. N., Fauser, B. C.J.M., Christ, J. P., Gunning, M. N., and Fauser, B. C.J.M.
- Published
- 2017
75. Are women with polycystic ovary syndrome at increased cardiovascular disease risk later in life?
- Author
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Gunning, M. N., Fauser, B. C.J.M., Gunning, M. N., and Fauser, B. C.J.M.
- Published
- 2017
76. RBM online : challenges ahead in scientific publishing
- Author
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Fauser, B C J M and Fauser, B C J M
- Published
- 2017
77. Endocrine and cardiometabolic cord blood characteristics of offspring born to mothers with and without polycystic ovary syndrome
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Daan, Nadine M P, Koster, Maria P H, Steegers-Theunissen, Regine P., Eijkemans, Marinus J C, Fauser, B. C J M, Daan, Nadine M P, Koster, Maria P H, Steegers-Theunissen, Regine P., Eijkemans, Marinus J C, and Fauser, B. C J M
- Published
- 2017
78. Implications of the 2014 Androgen Excess and Polycystic Ovary Syndrome Society guidelines on polycystic ovarian morphology for polycystic ovary syndrome diagnosis
- Author
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UMC Utrecht, MS VPG/Gynaecologie, Child Health, Brain, Circulatory Health, Christ, J. P., Gunning, M. N., Fauser, B. C.J.M., UMC Utrecht, MS VPG/Gynaecologie, Child Health, Brain, Circulatory Health, Christ, J. P., Gunning, M. N., and Fauser, B. C.J.M.
- Published
- 2017
79. Prolonged estrogen deprivation is associated with increased cardiovascular disease risk among women with primary ovarian insufficiency
- Author
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MS VPG/Gynaecologie, Biostatistiek Onderzoek, Infection & Immunity, Circulatory Health, Child Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Methodologie, Brain, Christ, J., Gunning, M., Palla, G., Eijkemans, R., Lambalk, Cornelis B., Laven, Joop S., Fauser, B., MS VPG/Gynaecologie, Biostatistiek Onderzoek, Infection & Immunity, Circulatory Health, Child Health, JC onderzoeksprogramma Infectieziekten, JC onderzoeksprogramma Methodologie, Brain, Christ, J., Gunning, M., Palla, G., Eijkemans, R., Lambalk, Cornelis B., Laven, Joop S., and Fauser, B.
- Published
- 2017
80. Are women with polycystic ovary syndrome at increased cardiovascular disease risk later in life?
- Author
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UMC Utrecht, MS VPG/Gynaecologie, Child Health, Brain, Circulatory Health, Gunning, M. N., Fauser, B. C.J.M., UMC Utrecht, MS VPG/Gynaecologie, Child Health, Brain, Circulatory Health, Gunning, M. N., and Fauser, B. C.J.M.
- Published
- 2017
81. RBM online: challenges ahead in scientific publishing
- Author
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MS VPG/Gynaecologie, Brain, Circulatory Health, Child Health, Fauser, B C J M, MS VPG/Gynaecologie, Brain, Circulatory Health, Child Health, and Fauser, B C J M
- Published
- 2017
82. Endocrine and cardiometabolic cord blood characteristics of offspring born to mothers with and without polycystic ovary syndrome
- Author
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MS VPG/Gynaecologie, Groep Timmers, Biostatistiek Onderzoek, Circulatory Health, Child Health, JC onderzoeksprogramma Methodologie, JC onderzoeksprogramma Infectieziekten, Brain, Infection & Immunity, Daan, Nadine M P, Koster, Maria P H, Steegers-Theunissen, Regine P., Eijkemans, Marinus J C, Fauser, B. C J M, MS VPG/Gynaecologie, Groep Timmers, Biostatistiek Onderzoek, Circulatory Health, Child Health, JC onderzoeksprogramma Methodologie, JC onderzoeksprogramma Infectieziekten, Brain, Infection & Immunity, Daan, Nadine M P, Koster, Maria P H, Steegers-Theunissen, Regine P., Eijkemans, Marinus J C, and Fauser, B. C J M
- Published
- 2017
83. Cardiovascular RiskprofilE - IMaging and gender-specific disOrders (CREw-IMAGO): rationale and design of a multicenter cohort study
- Author
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Zoet, GA, Meun, Cindy, Benschop, L, Boersma, Eric, Budde, Ricardo, Fauser, B, de Groot, CJM, van der Lugt, Aad, Maas, AIR, Moons, KGM, Roeters van Lennep, Jeanine, Roos - Hesselink, Jolien, Steegers, Eric, Rijn, BB, Laven, Joop, Franx, A (Arie), Velthuis, BK, Zoet, GA, Meun, Cindy, Benschop, L, Boersma, Eric, Budde, Ricardo, Fauser, B, de Groot, CJM, van der Lugt, Aad, Maas, AIR, Moons, KGM, Roeters van Lennep, Jeanine, Roos - Hesselink, Jolien, Steegers, Eric, Rijn, BB, Laven, Joop, Franx, A (Arie), and Velthuis, BK
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- 2017
84. Prolonged estrogen deprivation is associated with increased cardiovascular disease risk among women with primary ovarian insufficiency
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Christ, J., primary, Gunning, M., additional, Palla, G., additional, Eijkemans, R., additional, Lambalk, C.B., additional, Laven, J.S., additional, and Fauser, B., additional
- Published
- 2017
- Full Text
- View/download PDF
85. Are women with polycystic ovary syndrome at increased cardiovascular disease risk later in life?
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Gunning, M. N., primary and Fauser, B. C. J. M., additional
- Published
- 2017
- Full Text
- View/download PDF
86. Long-term follow-up after pre-eclampsia/HELLP syndrome
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van Pampus, M, Slager, E, Fauser, B, VanGeijn, H, Brolmann, H, and Vervest, H
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RENAL-FUNCTION ,medicine.medical_specialty ,Pediatrics ,hypertension ,Heart disease ,HELLP syndrome ,Renal function ,HEART-DISEASE ,Disease ,Preeclampsia ,renal disease ,PREGNANCY COMPLICATIONS ,HISTORY ,medicine ,risk factors ,COHORT ,reproductive and urinary physiology ,hepatic disease ,RISK ,Eclampsia ,business.industry ,brain lesions ,WOMEN ,General Medicine ,medicine.disease ,female genital diseases and pregnancy complications ,cardiovascular diseases ,Surgery ,PREECLAMPSIA ,embryonic structures ,Cohort ,business ,Psychosocial ,recurrence risk ,HELLP-SYNDROME - Abstract
Women with pre-eclampsia history are at increased risk for cardiovascular disease later in life. As pre-eclampsia is considered a vascular endothelial disease, the current interest in late cardiovascular complications is obvious. Moreover, there is much evidence that pre-eclampsia and cardiovascular disease share many risk factors. In contrast, information is scarce on possible late effects on organs commonly affected in pre-eclampsia/HELLP syndrome and eclampsia such as the kidney, the liver and the brain. Regarding the late psychosocial consequences of pre-eclampsia, there is growing evidence now that severe pre-eclampsia and/or HELLP syndrome may cause severe and long-lasting psychosomatic illness in some women postpartum. (c) 2005 Elsevier B.V. All rights reserved.
- Published
- 2005
87. Ulipristal acetate versus leuprolide acetate for uterine fibroids
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Donnez J., Tomaszewski J., Vaszquez F., Bouchard P., Lemieszczuk B., Barò F., Nouri K., Selvaggi L., Sodowski K., Bestel E., Terrill P., Osterloh I., Loumaye E., Barlow D. H., Barri P. N., Bergeron C., Bornstein J., Caraco Y., Carmona F., Caruso A., Diedrich K., Donnez O., Fauser B. C., Ferenczy A., Gilabert J., Giuliani A., Glezerman M., Goettker Schnetmann W., Hillemanns P., Huber J., Jimenez J. S., Kay R., Kiesel L., Kotarski J., Layani L., Mannering M., Marshall J., Martinez S., McPherson K., Melis G. B., Milani R., Morris E., Nisolle M., Palacios S., Parrilla J. J., Paul N. W., Pawlaczyk A., Pellicer A., Perino A., Vazquez F., Williams A. R., de Ziegler D., NAPPI, CARMINE, Donnez, J., Tomaszewski, J., Vaszquez, F., Bouchard, P., Lemieszczuk, B., Barò, F., Nouri, K., Selvaggi, L., Sodowski, K., Bestel, E., Terrill, P., Osterloh, I., Loumaye, E., Barlow, D. H., Barri, P. N., Bergeron, C., Bornstein, J., Caraco, Y., Carmona, F., Caruso, A., Diedrich, K., Donnez, O., Fauser, B. C., Ferenczy, A., Gilabert, J., Giuliani, A., Glezerman, M., Goettker Schnetmann, W., Hillemanns, P., Huber, J., Jimenez, J. S., Kay, R., Kiesel, L., Kotarski, J., Layani, L., Mannering, M., Marshall, J., Martinez, S., Mcpherson, K., Melis, G. B., Milani, R., Morris, E., Nappi, Carmine, Nisolle, M., Palacios, S., Parrilla, J. J., Paul, N. W., Pawlaczyk, A., Pellicer, A., Perino, A., Vazquez, F., Williams, A. R., and de Ziegler, D.
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myoma ,fibroid ,ulipristal - Published
- 2012
88. Outcome after Thrombectomy and Intravenous Thrombolysis in Patients with Acute Ischemic Stroke: A Prospective Observational Study
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Projectafdeling functional imaging, MS VPG/Gynaecologie, Brain, Circulatory Health, Child Health, Minnerup, Jens, Wersching, Heike, Teuber, Anja, Wellmann, Jürgen, Eyding, Jens, Weber, Ralph, Reimann, Gernot, Weber, Werner, Krause, Lars Udo, Kurth, Tobias, Berger, Klaus, Homberg, V., Petrovitch, A., Heuser, L., Mönnigs, P., Krogias, C., Wallner, B., Hennigs, S., Ahlers, A., Sahl, H., Ranft, A., Dobis, C., Brassel, F., Nolden-Koch, M., Schmitt, H., Chapot, R., Nordmeyer, H., Schlamann, M., Weimar, C., Busch, F., Busch, E. W., Sigges, E., Ruf, H., Wohlfahrt, K., Karatschai, R., Klein, B., Höhle, T., Haass, A., Nasreldein, A., Büchele, B., Gahn, G., Sterker, M., Hantel, T., Krämer, C., Henningsen, H., Adelt, I., König, M., Schmidt, C., Hofmann, A., Niederstadt, T., Unrath, M., Rehfeldt, T., Fauser, B., Pfeiffer, A., Lowens, S., Stögbauer, F., Staudacher, T., Erdmann, P., Grotemeyer, K. H., Spüntrup, E., Bücke, P., Wienecke, P., Faiss, J., Wolzik-Großmann, M., Brune, N., Isenmann, S., Thomas, C., Mucha, D., Projectafdeling functional imaging, MS VPG/Gynaecologie, Brain, Circulatory Health, Child Health, Minnerup, Jens, Wersching, Heike, Teuber, Anja, Wellmann, Jürgen, Eyding, Jens, Weber, Ralph, Reimann, Gernot, Weber, Werner, Krause, Lars Udo, Kurth, Tobias, Berger, Klaus, Homberg, V., Petrovitch, A., Heuser, L., Mönnigs, P., Krogias, C., Wallner, B., Hennigs, S., Ahlers, A., Sahl, H., Ranft, A., Dobis, C., Brassel, F., Nolden-Koch, M., Schmitt, H., Chapot, R., Nordmeyer, H., Schlamann, M., Weimar, C., Busch, F., Busch, E. W., Sigges, E., Ruf, H., Wohlfahrt, K., Karatschai, R., Klein, B., Höhle, T., Haass, A., Nasreldein, A., Büchele, B., Gahn, G., Sterker, M., Hantel, T., Krämer, C., Henningsen, H., Adelt, I., König, M., Schmidt, C., Hofmann, A., Niederstadt, T., Unrath, M., Rehfeldt, T., Fauser, B., Pfeiffer, A., Lowens, S., Stögbauer, F., Staudacher, T., Erdmann, P., Grotemeyer, K. H., Spüntrup, E., Bücke, P., Wienecke, P., Faiss, J., Wolzik-Großmann, M., Brune, N., Isenmann, S., Thomas, C., and Mucha, D.
- Published
- 2016
89. Approaches to improve the diagnosis and management of infertility
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Devroey P., Fauser B. C., Diedrich K., Baart E., Barrat C., Bergh C., Broekmans F., Evers J. L., Griesinger G., Keay S., Olivennes F., Serour G., Staessen C., Sunde A., Venetis C., Yarali H., Howles C. M., Jenkins J., ALVIGGI, CARLO, Devroey, P., Fauser, B. C., Diedrich, K., Alviggi, Carlo, Baart, E., Barrat, C., Bergh, C., Broekmans, F., Evers, J. L., Griesinger, G., Keay, S., Olivennes, F., Serour, G., Staessen, C., Sunde, A., Venetis, C., Yarali, H., Howles, C. M., Jenkins, J., Department of Embryology and Genetics, and Obstetrics & Gynecology
- Subjects
Male ,Infertility ,medicine.medical_specialty ,predictive factors ,Reproductive Techniques, Assisted ,Standardization ,media_common.quotation_subject ,medicine.medical_treatment ,Reproductive medicine ,MEDLINE ,Reviews ,Fertility ,Preimplantation genetic diagnosis ,single embryo transfer ,Embryo Culture Techniques ,Ovarian Follicle ,Ovulation Induction ,Humans ,Medicine ,infertility work-up ,Medical physics ,ovarian response ,media_common ,Cryopreservation ,Gynecology ,Assisted reproductive technology ,business.industry ,Age Factors ,Obstetrics and Gynecology ,Cost-effectiveness analysis ,Embryo Transfer ,Embryo, Mammalian ,Prognosis ,medicine.disease ,Treatment Outcome ,Reproductive Medicine ,Female ,business ,in vitro fertilization - Abstract
BACKGROUND Recent advances in our understanding of the causes of infertility and of assisted reproductive technology (ART) have led to the development of complex diagnostic tools, prognostic models and treatment options. The Third Evian Annual Reproduction (EVAR) Workshop Meeting was held on 26-27 April 2008 to evaluate evidence supporting current approaches to the diagnosis and management of infertility and to identify areas for future research efforts. METHODS Specialist reproductive medicine clinicians and scientists delivered presentations based on published literature and ongoing research on patient work-up, ovarian stimulation and embryo quality assessment during ART. This report is based on the expert presentations and subsequent group discussions and was supplemented with publications from literature searches and the authors' knowledge. RESULTS It was agreed that single embryo transfer (SET) should be used with increasing frequency in cycles of ART. Continued improvements in cryopreservation techniques, which improve pregnancy rates using supernumerary frozen embryos, are expected to augment the global uptake of SET. Adaptation and personalization of fertility therapy may help to optimize efficacy and safety outcomes for individual patients. Prognostic modelling and personalized management strategies based on individual patient characteristics may prove to represent real progress towards improved treatment. However, at present, there is limited good-quality evidence to support the use of these individualized approaches. CONCLUSIONS Greater quality control and standardization of clinical and laboratory evaluations are required to optimize ART practices and improve individual patient outcomes. Well-designed, good-quality studies are required to drive improvements to the diagnosis and management of ART processes.
- Published
- 2009
90. The Significance of Fragile X Mental Retardation Gene 1 CGG Repeat Sizes in the Normal and Intermediate Range in Women With Primary Ovarian Insufficiency EDITORIAL COMMENT
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Voorhuis, M., Onland-Moret, N. C., Janse, F., van Amstel, H. K. Ploos, Goverde, A. J., Lambalk, C. B., Laven, J. S. E., van der Schouw, Y. T., Broekmans, F. J. M., Fauser, B. C. J. M., Obstetrics and gynaecology, ICaR - Ischemia and repair, RS: GROW - Developmental Biology, and RS: GROW - R4 - Reproductive and Perinatal Medicine
- Abstract
Primary ovarian insufficiency (POI) refers to the cessation of menses before the age of 40 years and occurs in 1% to 2% of women. The specific cause of POI is unknown in the majority of cases. Known causes include gene mutations of fragile X mental retardation 1 (FMR1), a gene located on the X chromosome. This gene codes for a protein essential for normal cognitive development and female reproductive function. FMR1 contains a CCG trinucleotide segment in an untranslated region of its DNA that is repeated less than 45 times in normal individuals (normal range of repeats). Mutation of FMR1 results in abnormal expansion of an unstable CGG triplet, leading to impaired cognitive and reproductive function. Between 55 and 200 CCG repeats is called premutation; affected individuals with premutation are at risk for POI and further expansion of repeats in subsequent generations. People with 45 to 54 CCG repeats (intermediate range of repeats) are considered to be at borderline risk for POI and further expansion of repeats. This case-control study was designed to determine whether the risk of POI is associated with CGG repeat length of normal and intermediate range (up to 55 repeats) in a large cohort of Dutch women with idiopathic POI. The second aim of the study was to examine a possible association between the number of CGG repeats and age at first manifestation of POI as a measurement for the severity of POI. The study population was composed of 375 well-phenotyped Dutch women diagnosed with POI; control subjects were 3368 women with natural menopause at 40 years or older. The FMR1 CGG repeat number was determined by polymerase chain reaction amplification of DNA extracted from blood samples drawn from each patient. Fisher exact test was used to assess the prevalence of intermediate-size CGG repeats in POI cases and control subjects. Analysis of variance tested differences in mean CGG repeat lengths on alleles 1 and 2 between POI cases and control subjects. Allele 1 has the lowest triple repeat number, and allele 2 has the highest triple repeat number. There was no significant difference between POI cases and control subjects in the frequency of intermediate-size CGG repeats on allele 2 (POI 2.7 vs control subjects 3.8%; the odds ratio was 0.72, with a 95% confidence interval of 0.38-1.39; P = 0.38). Linear regression analysis showed no association between the number of CGG repeats and age at first POI manifestation ( = 20.019, P = 0.72). These data suggest that intermediate-size CGG repeats are not associated with risk of POI. Therefore, evaluation of normal and intermediate FMR1 repeat size appears to be of little or no value in the diagnostic workup of women affected by POI or in the prognostic assessment of women at risk of developing POI. Reasons for caution in interpreting these results are as follows: (1) FMR1 CGG repeat lengths in POI cases and control subjects were genotyped in 2 different laboratories; technical differences could have affected the results; (2) distributions of CGG repeats could vary among ethnic populations; (3) women with primary amenorrhea (n = 17) were included in the POI group. The last 2 possible limitations were unlikely because exclusion of data from nonwhite women or women with primary amenorrhea did not affect the results.
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- 2014
91. Renormalization of gauge fields using Hopf algebras
- Author
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Suijlekom, W.D. van, Fauser, B., Tolksdorf, J., Zeidler, E., Fauser, B., Tolksdorf, J., and Zeidler, E.
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ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Mathematical Physics - Abstract
Contains fulltext : 72251.pdf (Author’s version preprint ) (Open Access) 3rd Blaubeuren Workshop, july 2007
- Published
- 2008
92. Chromosome segregation regulation in human zygotes : Altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex
- Author
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Van De Werken, C., Avo Santos, M., Laven, J. S E, Eleveld, C., Fauser, B. C J M, Lens, S. M A, Baart, E. B., Van De Werken, C., Avo Santos, M., Laven, J. S E, Eleveld, C., Fauser, B. C J M, Lens, S. M A, and Baart, E. B.
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- 2015
93. Ovarian response prediction in GnRH antagonist treatment for IVF using anti-Müllerian hormone
- Author
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Hamdine, O., Eijkemans, M. J C, Lentjes, E. W G, Torrance, H. L., Macklon, N. S., Fauser, B. C J M, Broekmans, F. J., Hamdine, O., Eijkemans, M. J C, Lentjes, E. W G, Torrance, H. L., Macklon, N. S., Fauser, B. C J M, and Broekmans, F. J.
- Published
- 2015
94. Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive : II. Clinical effects
- Author
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Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., Coelingh Bennink, H. J T, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., and Coelingh Bennink, H. J T
- Published
- 2015
95. Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive : I. Endocrine effects
- Author
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Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., Coelingh Bennink, H. J T, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., and Coelingh Bennink, H. J T
- Published
- 2015
96. Androgen levels in women with various forms of ovarian dysfunction : Associations with cardiometabolic features
- Author
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Daan, N. M P, Jaspers, L., Koster, M. P H, Broekmans, F. J M, De Rijke, Y. B., Franco, O. H., Laven, J. S E, Kavousi, M., Fauser, B. C J M, Daan, N. M P, Jaspers, L., Koster, M. P H, Broekmans, F. J M, De Rijke, Y. B., Franco, O. H., Laven, J. S E, Kavousi, M., and Fauser, B. C J M
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- 2015
97. Chromosome segregation regulation in human zygotes: Altered mitotic histone phosphorylation dynamics underlying centromeric targeting of the chromosomal passenger complex
- Author
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MS VPG/Gynaecologie, Child Health, CMM Groep Lens, Cancer, Van De Werken, C., Avo Santos, M., Laven, J. S E, Eleveld, C., Fauser, B. C J M, Lens, S. M A, Baart, E. B., MS VPG/Gynaecologie, Child Health, CMM Groep Lens, Cancer, Van De Werken, C., Avo Santos, M., Laven, J. S E, Eleveld, C., Fauser, B. C J M, Lens, S. M A, and Baart, E. B.
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- 2015
98. Androgen levels in women with various forms of ovarian dysfunction: Associations with cardiometabolic features
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MS VPG/Gynaecologie, Child Health, MS Verloskunde, Cancer, Daan, N. M P, Jaspers, L., Koster, M. P H, Broekmans, F. J M, De Rijke, Y. B., Franco, O. H., Laven, J. S E, Kavousi, M., Fauser, B. C J M, MS VPG/Gynaecologie, Child Health, MS Verloskunde, Cancer, Daan, N. M P, Jaspers, L., Koster, M. P H, Broekmans, F. J M, De Rijke, Y. B., Franco, O. H., Laven, J. S E, Kavousi, M., and Fauser, B. C J M
- Published
- 2015
99. Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: II. Clinical effects
- Author
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MS VPG/Gynaecologie, Child Health, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., Coelingh Bennink, H. J T, MS VPG/Gynaecologie, Child Health, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., and Coelingh Bennink, H. J T
- Published
- 2015
100. Restoring testosterone levels by adding dehydroepiandrosterone to a drospirenone containing combined oral contraceptive: I. Endocrine effects
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MS VPG/Gynaecologie, Child Health, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., Coelingh Bennink, H. J T, MS VPG/Gynaecologie, Child Health, Zimmerman, Y., Foidart, J. M., Pintiaux, A., Minon, J. M., Fauser, B. C J M, Cobey, K., and Coelingh Bennink, H. J T
- Published
- 2015
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