51. Potential genotoxic effects of low-intensity ultrasound on fibroblasts, evaluated with the cytokinesis-block micronucleus assay
- Author
-
D. Pozzi, F. Luongo, Angelico Bedini, Agostina Congiu Castellano, Claudia Giliberti, Federico Bordi, Ion Udroiu, Fabio Domenici, Raffaele Palomba, Udroiu, Ion, Fabio, Domenici, Claudia, Giliberti, Angelico, Bedini, Raffaele, Palomba, Fabio, Luongo, Deleana, Pozzi, Federico, Bordi, and Agostina Congiu, Castellano
- Subjects
CBMN assay ,Health, Toxicology and Mutagenesis ,Biology ,Micronuclei ,medicine.disease_cause ,Toxicology ,Mice ,Ultrasound ,Genetics ,medicine ,Cytotoxic T cell ,Animals ,Cytotoxicity ,NIH-3T3 ,Micronuclei, Chromosome-Defective ,Settore CHIM/02 - Chimica Fisica ,micronucleu ,Genotoxicity ,Micronucleus ,3T3 Cells ,Fibroblasts ,Sound ,ultrasound ,business.industry ,genotoxicity ,cbmn assay ,nih-3t3 ,micronucleus ,In vitro ,Micronucleus test ,Cancer research ,business ,Chromosome-Defective ,Cytokinesis - Abstract
Although medical ultrasound offers compelling opportunities to improve therapy in principle, progress in the field has been limited because of an insufficient understanding of the potential genotoxic and cytotoxic effects of ultrasound on biological systems. This paper is mainly focused on an in vitro study of effects with respect to genotoxicity and viability induced by 1- and 3-MHz medical ultrasound in murine fibroblasts (NIH-3T3) at low-intensity exposure (spatial peak temporal average intensity Ita
- Published
- 2014