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52. [Isoflurane in spontaneous ventilation (in orthopedic surgery: comparison with halothane)].

Author

Foissac J, Slama S, Caillard B, and Allaert F

Subjects
Adolescent, Adult, Carbon Dioxide blood, Humans, Middle Aged, Pulmonary Ventilation drug effects, Random Allocation, Respiration drug effects, Anesthesia, Inhalation, Halothane pharmacology, Isoflurane pharmacology, Methyl Ethers, Orthopedics
Abstract

Isoflurane and halothane, two anaesthetics agents have been compared. Forty young and healthy patients were divided into two randomly selected group. Each of them was anaesthetized either with isoflurane or with halothane. Anaesthesia was maintained with nitrous-oxide and dextromoramide. During induction, the ventilation was spontaneous. Blood-gas, ventilation rate and tidal-volume were studied before induction, during anaesthesia and at the end of the surgery. Statistical data show a higher PaCO2 and a lower pH with isoflurane. This was increased by dextromoramide. During induction, complications occurred more after than with halothane but the emergence was better.

Published
1986

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