14,395 results on '"Espagne A"'
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52. Photosensitized oxidative addition to gold(i) enables alkynylative cyclization of o-alkylnylphenols with iodoalkynes
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Xia, Zhonghua, Corcé, Vincent, Zhao, Fen, Przybylski, Cédric, Espagne, Agathe, Jullien, Ludovic, Le Saux, Thomas, Gimbert, Yves, Dossmann, Héloïse, Mouriès-Mansuy, Virginie, Ollivier, Cyril, and Fensterbank, Louis
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- 2019
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53. The Added Value of Intraoperative Hypnosis during Spinal Cord Stimulation Lead Implantation under Awake Anesthesia in Patients Presenting with Refractory Chronic Pain
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Chantal Wood, Gaëlle Martiné, Gaëlle Espagne-Dubreuilh, Karine Le Goff, Maarten Moens, Lisa Goudman, Sandrine Baron, Romain David, Nicolas Naïditch, Maxime Billot, and Philippe Rigoard
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persistent spinal pain syndrome (PSPS) ,failed back surgery syndrome (FBSS) ,neuromodulation ,chronic pain ,surgery ,adjunct therapy ,Medicine (General) ,R5-920 - Abstract
To improve pain relief for refractory pain condition, spinal cord stimulation (SCS) needs to target the dedicated neuronal fibers within the dorsal columns. Intraoperative feedback from the patient can optimize lead placement but requires “awake surgery”, allowing interaction between patient and surgeon. This can produce negative effects like anxiety and stress. To better manage these aspects, we propose to combine intraoperative hypnosis with awake anesthesia. Seventy-four patients (35 females, 22–80 years) presenting with chronic refractory pain, were offered intraoperative hypnosis during awake SCS lead implantation. Interactive conversational hypnosis was used as well as interactive touch, which was enhanced during painful moments during the lead intraoperative programming. All patients participated actively during the intraoperative testing which helped to optimize the lead positioning. They kept an extremely positive memory of the surgery and of the hypnotic experience, despite some painful moments. Pain could be reduced in these patients by using interactions and touch, which works on Gate Control modulation. Positive memory was reinforced by congratulations to create self-confidence and to induce positive expectations, which could reinforce the Diffuse Noxious Inhibitory Controls at the spinal level. Cooperation was improved because the patient was actively participating and thus, much more alert when feedback was required. Combining intraoperative hypnosis with awake anesthesia appears helpful for SCS lead implantation. It enhances patient cooperation, allows optimization of lead positioning, and leads to better pain control, positive and resourceful memory.
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- 2022
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54. Viajando com o conceito de transferências culturais: entrevista com Michel Espagne
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Michel Espagne, Alexandre Fontaine, and Felipe Ziotti Narita
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Transferências culturais ,Modernidade ,Educação ,Historiografia ,Education (General) ,L7-991 - Abstract
Entrevista com Michel Espagne a respeito do campo de pesquisa das transferências culturais. A conversa foi realizada na École normale supérieure de la rue d'Ulm de Paris (França) e conduzida sob a coordenação de Alexandre Fontaine, pesquisador do Departamento de Educação da Universidade de Viena (Áustria). Tradução de Felipe Ziotti Narita. An interview with Michel Espagne on the problem of cultural transfers. The interview was held at École normale supérieure de la rue d'Ulm in Paris (France) and was coordinated by Alexandre Fontaine, researcher linked to the Department of Education of the University of Vienna (Austria). Translation: Felipe Ziotti Narita.
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- 2018
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55. Enlightenment Germany and the Invention of Siberia
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Michel Espagne
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Siberia ,Altai ,anthropology ,shamanism ,linguistics ,history of the humanities ,Russian Germans ,Literature (General) ,PN1-6790 - Abstract
During the period of German Enlightenment, German scholars at service in the Russian state began scientific exploration of Siberia and organized the “Great northern expedition” (1733–1743) which was later completed by other researchers. Johann Georg Gmelin, Carl Heinrich Merck, Georg Wilhelm Steller, Gerhard Friedrich Müller, and Peter Simon Pallas among others focused on the religious life, languages and everyday life of the Siberian ethnic groups they encountered. Their accounts remained for a long time unpublished as they were a “formal” property of the Russian Academy of Sciences. Not only are they a valuable contribution to the invention of Russian identity conceived as part of the Eurasian space, they also form the basis of new sciences such anthropology and linguistics resulting from the contact between German universities and the widely unexplored Siberian world.
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- 2018
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56. De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora, a model organism for fungal morphogenesis.
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Nowrousian, Minou, Stajich, Jason E, Chu, Meiling, Engh, Ines, Espagne, Eric, Halliday, Karen, Kamerewerd, Jens, Kempken, Frank, Knab, Birgit, Kuo, Hsiao-Che, Osiewacz, Heinz D, Pöggeler, Stefanie, Read, Nick D, Seiler, Stephan, Smith, Kristina M, Zickler, Denise, Kück, Ulrich, and Freitag, Michael
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Sordariales ,Neurospora crassa ,Gene Expression Profiling ,Sequence Analysis ,DNA ,Genomics ,Phylogeny ,Base Sequence ,Genome ,Fungal ,Genome ,Models ,Biological ,Molecular Sequence Data ,Developmental Biology ,Genetics - Abstract
Filamentous fungi are of great importance in ecology, agriculture, medicine, and biotechnology. Thus, it is not surprising that genomes for more than 100 filamentous fungi have been sequenced, most of them by Sanger sequencing. While next-generation sequencing techniques have revolutionized genome resequencing, e.g. for strain comparisons, genetic mapping, or transcriptome and ChIP analyses, de novo assembly of eukaryotic genomes still presents significant hurdles, because of their large size and stretches of repetitive sequences. Filamentous fungi contain few repetitive regions in their 30-90 Mb genomes and thus are suitable candidates to test de novo genome assembly from short sequence reads. Here, we present a high-quality draft sequence of the Sordaria macrospora genome that was obtained by a combination of Illumina/Solexa and Roche/454 sequencing. Paired-end Solexa sequencing of genomic DNA to 85-fold coverage and an additional 10-fold coverage by single-end 454 sequencing resulted in approximately 4 Gb of DNA sequence. Reads were assembled to a 40 Mb draft version (N50 of 117 kb) with the Velvet assembler. Comparative analysis with Neurospora genomes increased the N50 to 498 kb. The S. macrospora genome contains even fewer repeat regions than its closest sequenced relative, Neurospora crassa. Comparison with genomes of other fungi showed that S. macrospora, a model organism for morphogenesis and meiosis, harbors duplications of several genes involved in self/nonself-recognition. Furthermore, S. macrospora contains more polyketide biosynthesis genes than N. crassa. Phylogenetic analyses suggest that some of these genes may have been acquired by horizontal gene transfer from a distantly related ascomycete group. Our study shows that, for typical filamentous fungi, de novo assembly of genomes from short sequence reads alone is feasible, that a mixture of Solexa and 454 sequencing substantially improves the assembly, and that the resulting data can be used for comparative studies to address basic questions of fungal biology.
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- 2010
57. Genome Sequence of a Polydnavirus: Insights into Symbiotic Virus Evolution
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Espagne, Eric, Dupuy, Catherine, Huguet, Elisabeth, Cattolico, Laurence, Provost, Bertille, Martins, Nathalie, Poirié, Marylène, Periquet, Georges, and Drezen, Jean Michel
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- 2004
58. Theodor Lipps : de l'esthétique à l'histoire de l'art
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Espagne, Michel
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- 2017
59. Climat, finance et croissance : l'introuvable tango à trois des modèles économie-climat ?
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ESPAGNE, Étienne
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- 2017
60. Phosphatidylinositol 3-phosphate–binding protein AtPH1 controls the localization of the metal transporter NRAMP1 in Arabidopsis
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Agorio, Astrid, Giraudat, Jérôme, Bianchi, Michele Wolfe, Marion, Jessica, Espagne, Christelle, Castaings, Loren, Lelièvre, Françoise, Curie, Catherine, Thomine, Sébastien, and Merlot, Sylvain
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- 2017
61. Near-infrared co-illumination of fluorescent proteins reduces photobleaching and phototoxicity
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Ludvikova, Lucie, primary, Simon, Emma, additional, Deygas, Mathieu, additional, Panier, Thomas, additional, Plamont, Marie-Aude, additional, Ollion, Jean, additional, Tebo, Alison, additional, Piel, Matthieu, additional, Jullien, Ludovic, additional, Robert, Lydia, additional, Le Saux, Thomas, additional, and Espagne, Agathe, additional
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- 2023
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62. Multiscale Transient Absorption Study of the Fluorescent Protein Dreiklang and Two Point Variants Provides Insight into Photoswitching and Nonproductive Reaction Pathways
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Renouard, Emilie, primary, Nowinska, Magdalena, additional, Lacombat, Fabien, additional, Plaza, Pascal, additional, Müller, Pavel, additional, and Espagne, Agathe, additional
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- 2023
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63. Alain Deligne, L’itinéraire philosophique du jeune Éric Weil. Hambourg-Berlin-Paris
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Espagne, Michel, primary
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- 2023
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64. Planification écologique et changement structurel
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Étienne Espagne and Guilherme Magacho
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- 2022
65. Impacts of the CBAM on EU trade partners: consequences for developing countries.
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Magacho, Guilherme, Espagne, Etienne, and Godin, Antoine
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COUNTRIES , *EMERGING markets , *CARBON pricing , *SOCIOECONOMIC factors , *MACROECONOMIC models , *CARBON emissions ,DEVELOPING countries - Abstract
This article analyses the impact of the introduction of the Carbon Border Adjustment Mechanism (CBAM) on European Union (EU) trade partners, focusing especially on its potential socio-economic and external consequences for developing and emerging economies (EMDEs). It uses trade data and Multi-Regional Input-Output (MRIO) matrices to investigate the geographically and sectorally uneven distribution of CBAM's potential impacts. The introduction of the CBAM by the EU is still under discussion. This mechanism, which seeks to reduce the incentives for firms to outsource their carbon emissions and promote a more generalised low-carbon transition, might disproportionally expose some non-EU economies. In absolute terms, Russia, China, Turkey, and Ukraine are the main EU trade partners in CBAM products, and hence the most exposed countries in external and socio-economic dimensions. In relative terms, the degree of exposure of economies that export CBAM products to Europe varies substantially, with many developing economies having more than 2% of their exports and 1% of their production impacted by this measure. East European economies, mainly in the Balkans, as well as Mozambique, Zimbabwe, and Cameroon in Africa, are the most exposed as far as the external dimension is concerned. In socio-economic terms, we can also include Morocco and Tajikistan to the group of most exposed economies. In the end, promoting the substitution of highly polluting technologies with green technologies seems notably easier in Europe than in EMDEs. Many jobs, tax revenues, and export revenues will be lost if the CBAM is implemented without taking into account the specificities of the EU's trading partners. We discuss options to mitigate adverse consequences on EMDEs. The CBAM is a logical complementary policy to the EU-ETS, which aims to avoid EU industries outsourcing their production to countries that do not adopt similar levels of carbon pricing. Although most macroeconomic models generally assume that all countries have a relatively high capacity to migrate from one industry to another, evidence shows otherwise. Previous results analysing the impacts of the CBAM might hence have underestimated the consequences for developing and emerging economies. Accounting for rigidities in the production structure, we show that the CBAM may have a regressive impact, therefore requiring careful attention to its institutional design, especially if the objective is to reinforce global climate ambitions in line with the EU's own decarbonisation strategy. Promoting the substitution of highly polluting technologies with green technologies seems notably easier in Europe than in EMDEs. Many jobs, tax revenues, and export revenues will be lost if the CBAM is implemented without taking into account the specificities of the EU's trading partners. One possible way to minimise its side effects is to exempt the so-called least developed countries from the CBAM. Rather than an exemption, these countries could also receive targeted support from the EU to reduce their dependence on highly emitting industries, via transfer of technologies, climate subsidies, or concessional lending. The adoption of CBAM-like measures in other developed economies, such as Japan and North America, as well as in wealthier developing countries with the capacity to decarbonise their industries, such as China, would exacerbate the fragilities of emerging and developing economies unless counter-measures are taken. [ABSTRACT FROM AUTHOR]
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- 2024
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66. HEINRICH HEINE TRADUCTEUR DE GÉRARD DE NERVAL ?
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Espagne, Michel
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- 2024
67. Présentation
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Aglietta, Michel, primary and Espagne, Étienne, additional
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- 2019
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68. Chapitre 8. Dynamiques du capitalocène
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Espagne, Étienne, primary
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- 2019
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69. Un projet de dictionnaire sino-européen des concepts critiques
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Espagne, Michel, primary
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- 2019
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70. Introduction
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Espagne, Michel, primary, Isaxanli, Hamlet, additional, and Mustafayev, Shahin, additional
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- 2019
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71. 7. De Julius Klaproth à Friedrich Bodenstedt
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Espagne, Michel, primary
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- 2019
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72. Transferts et échanges savants
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Espagne, Michel, primary
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- 2019
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73. Plural Globality and Shift in Perspective
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Espagne, Michel, primary
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- 2019
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74. Préface
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Espagne, Michel, primary
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- 2019
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75. Alain Deligne, L’itinéraire philosophique du jeune Éric Weil. Hambourg-Berlin-Paris
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Espagne, Michel
- Abstract
Éric Weil fait partie des figures les plus marquantes de la philosophie française des années 1945 à 1975 et l’Institut Éric Weil à l’université de Lille illustre l’importance de son apport. Or, il venait d’Allemagne et devait sa formation philosophique à la fréquentation de plusieurs universités allemandes. L’ouvrage d’Alain Deligne met en évidence l’itinéraire philosophique du jeune Éric Weil en Allemagne, en accompagnant cette biographie intellectuelle d’un choix important de textes inédits...
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- 2023
76. Money, Finance and Climate: The Elusive Quest for a Truly Integrated Assessment Model
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Espagne, Etienne
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Climate change -- Conferences, meetings and seminars ,Financial services -- Environmental aspects -- Economic aspects ,Financial services industry ,Business, general ,Business ,Economics - Abstract
In this paper, we show how existing IAMs generally omit any representation of a financial sector. We then discuss the potential impacts of climate change policies and climate change events on the financial sector as shown in the existing literature. We underline how the structure of the financial sector itself could impact the carbon trend of the economy. We then see how these specific linkages between the financial and the climate sector can be represented in new types of IAMs, and how they have already started to be addressed, notably in the stock- flow consistent models literature. We conclude on the necessary convergence agenda between climate policies addressing the financial goals in article 2 of the Paris Agreement and financial sector reforms to dampen the intrinsic financial instability. Keywords Climate finance * Paris Agreement * IAM * Financial instability * Stockflow consistent models JEL Classification Q54 Q57 * E6 * E12 * G1, The adoption of the Paris Agreement on December 12, 2015, as a conclusion of the 21st Conference of the Parties (COP21) at the United Nations Framework Convention on Climate Change [...]
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- 2018
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77. OnabotulinumtoxinA injections in chronic migraine, targeted to sites of pericranial myofascial pain: an observational, open label, real-life cohort study
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Danièle Ranoux, Gaelle Martiné, Gaëlle Espagne-Dubreuilh, Marlène Amilhaud-Bordier, François Caire, and Laurent Magy
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Medicine - Abstract
Abstract Background OnabotulinumtoxinA has proven its efficacy in reducing the number of headache days in chronic migraine (CM) patients. The usual paradigm includes 31 pericranial injection sites with low dose (5 U) per site. The aim of this study is to present the results obtained using a simpler injection protocol of onabotulinumtoxinA, with injection sites targeted to pericranial myofascial sites of pain. Methods Observational, open label, real-life, cohort study. We enrolled 63 consecutive patients fulfilling the diagnostic criteria of CM, and refractory to conventional treatments. The patients were injected using a “follow-the-pain” pattern into the corrugator and/or temporalis and/or trapezius muscles. The doses per muscle were fixed. According to the number of muscles injected, the total dose could vary from 70 to 150 U per session. Patients were considered responders if they had a ≥ 50% decrease in number of headache days in at least two consecutive injection cycles. Results Forty one patients (65.1% in intention to treat analysis) responded to treatment. In 70.7% of responders, the effect size was even higher, with a reduction ≥70% in the number of headache days. The associated cervical pain and muscle tenderness, present in 33 patients, was reduced by ≥50% in 31 patients (94%). Triptan consumption dramatically decreased (81%) in responders. The trapezius was the most frequently injected muscle. We observed no serious adverse event. The mean patient satisfaction rate was 8.5/10. Conclusions This study provides additional robust evidence supporting the efficacy of onabotulinumtoxinA injections in CM. Furthermore, the paradigm we used, with reduced number of injection sites targeted to pericranial myofascial sites of pain, may provide evidence in favor of the implication of myofascial trigger points in migraine chronicization. Trial Registration ClinicalTrials.gov Protocol Record I17022 ClinicalTrials.gov Identifier: NCT03175263 . Date of registration: June 7, 2017. Retrospectively registered.
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- 2017
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78. Mythes et dieux dans la Psychologie des peuples
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Espagne, Michel
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Materials Chemistry - Abstract
Dans le volume de la Psychologie des peuples paru en 1915 Wundt aborde la question des relations entre mythe et religion. Il s’appuie sur des travaux préalables de Usener, Tylor, Frazer, Strehlow, etc. Il insiste sur le fait que la légende héroïque, célébrant des héros locaux, est antérieure aux mythes divins et il faut la réunion du héros et du démon pour permettre l’apparition d’un dieu. La légende des dieux se distingue en outre de la légende héroïque par le fait qu’elle génère une cosmologie. Mais la religion dépend surtout de la pratique collective du culte. Le monothéisme se développe en même temps que la philosophie. Chaque élément de la construction religieuse lorsqu’on l’analyse apparaît comme le résultat d’un syncrétisme et d’une histoire dont les textes épiques fondateurs ont conservé la mémoire. In dem 1915 erschienenen Band der Völkerpsychologie befasst sich Wundt mit dem Verhältnis von Mythos und Religion. Er bezieht sich dabei auf frühere Arbeiten von Usener, Tylor, Frazer, Strehlow usw. Er vertritt den Standpunkt, dass die Heldenlegende, die lokale Helden feiert, den Mythen der Götter vorausgeht und dass die Vereinigung des Helden und des Dämons erforderlich ist, um die Erscheinung eines Gottes zu ermöglichen. Die Göttersage unterscheidet sich weiter von der Heldensage dadurch, dass sie eine Kosmologie hervorbringt. Aber Religion hängt vor allem von der kollektiven Ausübung der Kulthandlung ab. Der Monotheismus entwickelt sich gleichzeitig mit der Philosophie. Jedes Element der religiösen Konstruktion scheint bei näherer Betrachtung das Ergebnis eines Synkretismus und einer Geschichte zu sein, die die epischen Gründungstexte in Erinnerung behalten haben. In the volume of the Völkerpsychologie published in 1915 Wundt addresses the question of the relationship between myth and religion. He builds on previous works by Usener, Tylor, Frazer, Strehlow etc. He insists that the heroic legend, celebrating local heroes, predates divine myths and he observes that the reunion of the hero and the demon is necessary to allow the creation of a god. The legend of the gods is further distinguished from the heroic legend by the fact that it generates a cosmology. But religion depends above all on the collective practice of worship. Monotheism develops at the same time as philosophy. Each element of religious construction when analyzed appears to be the result of a syncretism and a history which the founding epic texts have memorized.
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- 2022
79. Les concepts en sciences de l’Antiquité : mode d’emploi
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Anca Dan, Huang Yang, Hyun Jin Kim, David Konstan, and Michel Espagne
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History ,Classics - Published
- 2022
80. Typhoons and urbanization in Vietnam
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Espagne, Étienne, primary, Ha, Yen Boi, additional, Houngbedji, Kenneth, additional, and Ngo-Duc, Thanh, additional
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- 2023
- Full Text
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81. Impacts of the CBAM on EU trade partners: consequences for developing countries
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Magacho, Guilherme, primary, Espagne, Etienne, additional, and Godin, Antoine, additional
- Published
- 2023
- Full Text
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82. An Agent-Based Model for Land-Use Change Adaptation Strategies in the Context of Climate Change and Land Subsidence in the Mekong Delta
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Truong, Quang Chi, primary, Drogoul, Alexis, additional, Gaudou, Benoit, additional, Taillandier, Patrick, additional, Huynh, Nghi Quang, additional, Nguyen, Thao Hong, additional, Minderhoud, Philip, additional, Nguyen Thi Thu, Ha, additional, and Espagne, Etienne, additional
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- 2023
- Full Text
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83. OnabotulinumtoxinA injections in chronic migraine, targeted to sites of pericranial myofascial pain: an observational, open label, real-life cohort study
- Author
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Ranoux, Danièle, Martiné, Gaelle, Espagne-Dubreuilh, Gaëlle, Amilhaud-Bordier, Marlène, Caire, François, and Magy, Laurent
- Published
- 2017
- Full Text
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84. Conveni de col·laboració entre l'Ajuntament de Barcelona i Orange Espagne, S.A. per a l'ocupació del domini públic local
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Ajuntament de Barcelona, Orange Espagne, S.A., Ajuntament de Barcelona, and Orange Espagne, S.A.
- Published
- 2023
85. An Agent-Based Model for Land-Use Change Adaptation Strategies in the Context of Climate Change and Land Subsidence in the Mekong Delta
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Truong, Quang Chi, Drogoul, Alexis, Gaudou, Benoit, Taillandier, Patrick, Huynh, Nghi Quang, Nguyen, Thao Hong, Minderhoud, Philip, Nguyen thi thu, Ha, Espagne, Etienne, Truong, Quang Chi, Drogoul, Alexis, Gaudou, Benoit, Taillandier, Patrick, Huynh, Nghi Quang, Nguyen, Thao Hong, Minderhoud, Philip, Nguyen thi thu, Ha, and Espagne, Etienne
- Abstract
The Mekong Delta region has been seriously affected by climate change, with increasing temperatures, sea-level rise, and salinization strongly impacting agricultural activities of the region. Recent studies have shown that groundwater exploitation also contributes significantly to land subsidence throughout the delta. Thus, combating climate change now makes it necessary to design strategies and policies for adapting to and mitigating climate change and subsidence, not only at the individual level (mainly farmers), but also at the institutional level (province and region). This study aims to build an integrated model for the purpose of exploring the socio-economic impact of adaptation strategies provinces choose under various climate and economic scenarios. The LUCAS–GEMMES model (an agent-based model for strategies for adapting to land-use change in the context of climate change) was developed in order to evaluate socio-economic factors, climate, and water use by farmers, as well as the subsidence dynamics and macroeconomic trends in land-use selection strategies. The simulations are carried out according to four main scenarios: (i) lack of provincial adaptation strategies and absence of subsidence dynamics, (ii) lack of adaptation strategies though subsidence and the impact of land-use production benefits, (iii) purely individual adaptation strategies combined with the impact of subsidence, and (iv) provincial and individual-scale adaptation combined with the impact of subsidence. In all the scenarios that consider subsidence, our results show that early response decisions to even low-level subsidence lead to many positive outcomes in water resource management, such as a significant reduction in water-use in the dry season and a reduction in the area vulnerable to subsidence and climate change. However, the same results also indicate a possible decrease in farmers’ income due to reduced agricultural seasons and restricted land-use transformation, which demonstrate
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- 2023
86. HDL anti-inflammatory function is impaired and associated with high SAA1 and low APOA4 levels in aneurysmal subarachnoid hemorrhage
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Ambassade de France en Espagne, Junta de Andalucía, European Commission, Universidad de Sevilla, Ruiz de Azúa-López, Zaida, Pezzotti, María R., González-Díaz, Ángela, Meilhac, Olivier, Ureña, Juan, Amaya-Villar, Rosario, Castellano, Antonio, Varela, Lourdes, Ambassade de France en Espagne, Junta de Andalucía, European Commission, Universidad de Sevilla, Ruiz de Azúa-López, Zaida, Pezzotti, María R., González-Díaz, Ángela, Meilhac, Olivier, Ureña, Juan, Amaya-Villar, Rosario, Castellano, Antonio, and Varela, Lourdes
- Abstract
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease with high morbidity and mortality rates. Within 24 hours after aSAH, monocytes are recruited and enter the subarachnoid space, where they mature into macrophages, increasing the inflammatory response and contributing, along with other factors, to delayed neurological dysfunction and poor outcomes. High-density lipoproteins (HDL) are lipid-protein complexes that exert anti-inflammatory effects but under pathological conditions undergo structural alterations that have been associated with loss of functionality. Plasma HDL were isolated from patients with aSAH and analyzed for their anti-inflammatory activity and protein composition. HDL isolated from patients lost the ability to prevent VCAM-1 expression in endothelial cells (HUVEC) and subsequent adhesion of THP-1 monocytes to the endothelium. Proteomic analysis showed that HDL particles from patients had an altered composition compared to those of healthy subjects. We confirmed by western blot that low levels of apolipoprotein A4 (APOA4) and high of serum amyloid A1 (SAA1) in HDL were associated with the lack of anti-inflammatory function observed in aSAH. Our results indicate that the study of HDL in the pathophysiology of aSAH is needed, and functional HDL supplementation could be considered a novel therapeutic approach to the treatment of the inflammatory response after aSAH.
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- 2023
87. Las transferencias culturales. Campos de aplicación y tendencias de investigación
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Michel Espagne
- Published
- 2023
88. An Agent-Based Model for Land-Use Change Adaptation Strategies in the Context of Climate Change and Land Subsidence in the Mekong Delta
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Quang Chi Truong, Alexis Drogoul, Benoit Gaudou, Patrick Taillandier, Nghi Quang Huynh, Thao Hong Nguyen, Philip Minderhoud, Ha Nguyen Thi Thu, Etienne Espagne, Can Tho University [Vietnam] (CTU), Unité de modélisation mathématique et informatique des systèmes complexes [Bondy] (UMMISCO), Université de Yaoundé I-Institut de la francophonie pour l'informatique-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Université Gaston Bergé (Saint-Louis, Sénégal)-Université Cadi Ayyad [Marrakech] (UCA)-Sorbonne Université (SU)-Institut de Recherche pour le Développement (IRD [France-Nord]), Thuyloi University, Institut de Recherche pour le Développement (IRD), Systèmes Multi-Agents Coopératifs (IRIT-SMAC), Institut de recherche en informatique de Toulouse (IRIT), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Unité de Mathématiques et Informatique Appliquées de Toulouse (MIAT INRAE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Wageningen University and Research [Wageningen] (WUR), Deltares [The Netherlands], Università degli Studi di Padova = University of Padua (Unipd), Laboratoire d'Analyse des Sociétés, Transformations et Adaptations (LASTA), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Agence française de développement (AFD), and Projet GEMMES Vietnam, AFD
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Renewable Energy, Sustainability and the Environment ,Geography, Planning and Development ,agent-based modeling ,Building and Construction ,adaptation ,Management, Monitoring, Policy and Law ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,land-use change ,Bodemgeografie en Landschap ,land subsidence ,climate change ,[SDE]Environmental Sciences ,Soil Geography and Landscape ,Life Science - Abstract
International audience; The Mekong Delta region has been seriously affected by climate change, with increasing temperatures, sea-level rise, and salinization strongly impacting agricultural activities of the region. Recent studies have shown that groundwater exploitation also contributes significantly to land subsidence throughout the delta. Thus, combating climate change now makes it necessary to design strategies and policies for adapting to and mitigating climate change and subsidence, not only at the individual level (mainly farmers), but also at the institutional level (province and region). This study aims to build an integrated model for the purpose of exploring the socioeconomic impact of adaptation strategies provinces choose under various climate and economic scenarios. The LUCAS-GEMMES model (an agent-based model for strategies for adapting to land-use change in the context of climate change) was developed in order to evaluate socioeconomic factors, climate, and water use by farmers, as well as the subsidence dynamics and macroeconomic trends in land-use selection strategies. The simulations are carried out according to four main scenarios: (i) lack of provincial adaptation strategies and absence of subsidence dynamics, (ii) lack of adaptation strategies though subsidence and the impact of land-use production benefits, (iii) purely individual adaptation strategies combined with the impact of subsidence, and (iv) provincial and individual-scale adaptation combined with the impact of subsidence. In all the scenarios that consider subsidence, our results show that early response decisions to even low-level subsidence lead to many positive outcomes in water resource management, such as a significant reduction in water-use in the dry season and a reduction in the area vulnerable to subsidence and climate change. However, the same results also indicate a possible decrease in farmers' income due to reduced agricultural seasons and restricted land-use transformation, which demonstrates the importance of modeling the multi-sectoral aspects of adaptation. Finally, at a more general level, in the fourth scenario, the model clearly shows the benefits when provinces located in the same agro-ecological zone harmonize strategies, thus paving the way for defining integrated land-use policies at the regional level.
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- 2023
- Full Text
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89. How to Write Modern European History Today? Statements to Jörn Leonhard’s JMEH-Forum
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Espagne, Michael, Kreienbaum, Jonas, Cooper, Frederic, Conrad, Christoph, and Ther, Philipp
- Published
- 2016
90. LUCAS-GEMMES : Integrated dynamics of adaptation strategies in the Vietnamese Mekong Delta
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Truong, Chi Quang, Drogoul, Alexis, Gaudou, Benoit, Taillandier, Patrick, Huynh Quang, Nghi, Brugière, Arthur, Thi Thu Nguyen, Ha, Minderhoud, Philip, Espagne, Etienne, Can Tho University [Vietnam] (CTU), Unité de modélisation mathématique et informatique des systèmes complexes [Bondy] (UMMISCO), Université de Yaoundé I-Institut de la francophonie pour l'informatique-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Université Gaston Bergé (Saint-Louis, Sénégal)-Université Cadi Ayyad [Marrakech] (UCA)-Sorbonne Université (SU)-Institut de Recherche pour le Développement (IRD [France-Nord]), Université Toulouse Capitole (UT Capitole), Université de Toulouse (UT), Systèmes Multi-Agents Coopératifs (IRIT-SMAC), Institut de recherche en informatique de Toulouse (IRIT), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université Toulouse Capitole (UT Capitole), Unité de Mathématiques et Informatique Appliquées de Toulouse (MIAT INRAE), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Thuyloi University, Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Wageningen University and Research [Wageningen] (WUR), Agence française de développement (AFD), AFD : Agence française de développement, Woillez, Marie-Noël, Espagne, Etienne, and GEMMES
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Mekong Delta ,[INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA] ,Vietnamese ,[INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation ,[INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI] - Abstract
International audience; The predominantly agricultural Mekong Delta region will be profoundly affected by the effects of climate change, such as rising temperatures, sea level rise, and salinization. But recent studies show that other factors, such as sand mining and groundwater exploitation, will also largely contribute to future pressures, particularly through land subsidence. Alongside the fight against climate change, this makes it necessary to design strategies and policies for subsidence mitigation, not only at the individual level (mainly farmers), but also at the institutional level (province and region). Indeed, in the Vietnamese Mekong Delta (VMD), local provinces play a crucial role in the choice and implementation of strategies for the exploitation of natural resources, such as water or sand. However, the VMD is also a complex system in which the decisions of one province can have indirect effects on the other 12 provinces, especially because some provinces share common agro-ecological regions and aquifer areas. This chapter aims to explore, through simulation of an integrated model, the economic impact on farmers of the adaptation strategies chosen by the provinces under a number of climatic and economic scenarios. It thus builds on the adaptation options evaluated in Part 3 of the report. In particular, one objective is to understand which conditions of inter-province coordination on groundwater exploitation in common agro-ecological areas could improve the economic situation of farmers. To this end, the LUCAS model (an agent-based model for land-use change adaptation strategies in the context of climate change) [ Truong et al., 2021 ] was extended to take groundwater use by farmers into account, as well as the subsidence dynamics and macroeconomic trends from the GEMMES model. In the updated model, called LUCAS-GEMMES, subsidence-related adaptation strategies chosen at the provincial level and their interactions with individual decisions were also introduced. The simulation is performed with 4 experiments including (i) No provincial adaptation strategies and ignorance of subsidence dynamics; (ii) No adaptation strategies while subsidence impacts the benefit of land-use production; (iii) Individual adaptation strategies combined with the impact of subsidence; (iv) Province and individual adaptation combined with the impact of subsidence.The results show that decisions in early response to low-level subsidence bring many positive results in resource management, such as significantly reducing water use in the dry season, and reducing the vulnerability area from subsidence and climate change. The results also show a decrease in incomes in case of adaptation. Therefore, it is necessary to have investment solutions (technical support in shrimp farming, studying for new upland crops in the dry season) for new land-use types that could compensate for the economic benefits lost when applying policies that restrict people in the use of resources.; La région du delta du Mékong, essentiellement agricole, sera profondément touchée par les effets du changement climatique, tels que la hausse des températures, l’élévation du niveau de la mer et la salinisation. Mais des études récentes montrent que d’autres facteurs, comme l’extraction de sable et l’exploitation des eaux souterraines, contribueront également fortement aux pressions futures, notamment par la subsidence. Au-delà de la lutte contre le changement climatique, il est donc nécessaire de concevoir des stratégies et des politiques d’atténuation de la subsidence, non seulement au niveau individuel (principalement les agriculteurs), mais aussi au niveau institutionnel (province et région). En effet, dans le delta du Mékong vietnamien (DMV), les provinces locales jouent un rôle crucial dans le choix et la mise en œuvre des stratégies d’exploitation des ressources naturelles, comme l’eau ou le sable. Cependant, le DMV est aussi un système complexe dans lequel les décisions d’une province peuvent avoir des effets indirects sur les 12 autres provinces, notamment parce que certaines provinces partagent des régions agro-écologiques et des zones aquifères communes. Ce chapitre vise à explorer, par la simulation d’un modèle intégré, l’impact économique sur les agriculteurs des stratégies d’adaptation choisies par les provinces dans un certain nombre de scénarios climatiques et économiques. Il s’appuie donc sur les options d’adaptation évaluées dans la partie 3 du rapport. En particulier, un objectif est de comprendre dans quelles conditions de coordination entre les provinces sur l’exploitation des eaux souterraines, dans des zones agro-écologiques communes, la situation économique des agriculteurs peut s’améliorer. À cette fin, le modèle LUCAS (un modèle “basé agents” pour les stratégies d’adaptation au changement d’utilisation des terres dans le contexte du changement climatique) [ Truong et al., 2021 ] a été étendu pour prendre en compte l’utilisation des eaux souterraines par les agriculteurs, ainsi que la dynamique de subsidence et les tendances macroéconomiques du modèle GEMMES. Dans le modèle mis à jour, appelé LUCAS-GEMMES, les stratégies d’adaptation liées à la subsidence choisies au niveau provincial et leurs interactions avec les décisions individuelles ont également été introduites. La simulation est réalisée à l’aide de quatre expériences : (i) aucune stratégie d’adaptation provinciale et ignorance de la dynamique de la subsidence ; (ii) aucune stratégie d’adaptation alors que la subsidence a un impact sur le bénéfice de la production de l’utilisation des terres ; (iii) stratégies d’adaptation individuelles combinées à l’impact de la subsidence ; (iv) adaptation provinciale et individuelle combinée à l’impact de la subsidence. Les résultats montrent que les décisions prises en réponse précoce à un affaissement de faible niveau apportent de nombreux résultats positifs dans la gestion des ressources, tels que la réduction significative de l’utilisation de l’eau pendant la saison sèche, puis la réduction de la zone de vulnérabilité à la subsidence et au changement climatique. Les résultats montrent également une diminution des revenus en cas d’adaptation. Par conséquent, il est nécessaire d’avoir des solutions d’investissement (soutien technique dans l’élevage de crevettes, étude de nouvelles cultures de montagne en saison sèche) pour de nouveaux types d’utilisation des terres qui compenseraient les avantages économiques perdus lors de l’application de politiques qui limitent les personnes dans l’utilisation des ressources.
- Published
- 2022
91. Introduction
- Author
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Dmitrieva, Ekaterina, primary, Alexeiev, Pavel, additional, and Espagne, Michel, additional
- Published
- 2018
- Full Text
- View/download PDF
92. 14. L’Allemagne des Lumières et la science de la Sibérie
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Espagne, Michel, primary
- Published
- 2018
- Full Text
- View/download PDF
93. Macroscale fluorescence imaging against autofluorescence under ambient light
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Zhang, Ruikang, Chouket, Raja, Plamont, Marie-Aude, Kelemen, Zsolt, Espagne, Agathe, Tebo, Alison G., Gautier, Arnaud, Gissot, Lionel, Faure, Jean-Denis, Jullien, Ludovic, Croquette, Vincent, and Le Saux, Thomas
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- 2018
- Full Text
- View/download PDF
94. Taine et les racines allemandes d’une méthode
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Michel Espagne
- Published
- 2022
95. Policy Responses to Cope with COVID-19 in Viet Nam: An Empirical Stock-Flow-Consistent Approach
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Thi Thu Ha Nguyen, Luis Reyes, Etienne Espagne, and Thi Anh-Dao Tran
- Published
- 2023
96. Ecological macroeconomics
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Étienne Espagne, Antoine Godin, and Romain Svartzman
- Published
- 2023
97. Impacts of the CBAM on EU trade partners: consequences for developing countries
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Guilherme Magacho, Etienne Espagne, and Antoine Godin
- Subjects
Atmospheric Science ,Global and Planetary Change ,Environmental Science (miscellaneous) ,Management, Monitoring, Policy and Law - Abstract
This article analyses the impact of the introduction of the Carbon Border Adjustment Mechanism (CBAM) on European Union (EU) trade partners, focusing especially on its potential socio-economic and external consequences for developing and emerging economies (EMDEs). It uses trade data and Multi-Regional Input-Output (MRIO) matrices to investigate the geographically and sectorally uneven distribution of CBAM’s potential impacts. The introduction of the CBAM by the EU is still under discussion. This mechanism, which seeks to reduce the incentives for firms to outsource their carbon emissions and promote a more generalised low-carbon transition, might disproportionally expose some non-EU economies. In absolute terms, Russia, China, Turkey, and Ukraine are the main EU trade partners in CBAM products, and hence the most exposed countries in external and socio-economic dimensions. In relative terms, the degree of exposure of economies that export CBAM products to Europe varies substantially, with many developing economies having more than 2% of their exports and 1% of their production impacted by this measure. East European economies, mainly in the Balkans, as well as Mozambique, Zimbabwe, and Cameroon in Africa, are the most exposed as far as the external dimension is concerned. In socio-economic terms, we can also include Morocco and Tajikistan to the group of most exposed economies. In the end, promoting the substitution of highly polluting technologies with green technologies seems notably easier in Europe than in EMDEs. Many jobs, tax revenues, and export revenues will be lost if the CBAM is implemented without taking into account the specificities of the EU’s trading partners. We discuss options to mitigate adverse consequences on EMDEs. The CBAM is a logical complementary policy to the EU-ETS, which aims to avoid EU industries outsourcing their production to countries that do not adopt similar levels of carbon pricing.Although most macroeconomic models generally assume that all countries have a relatively high capacity to migrate from one industry to another, evidence shows otherwise. Previous results analysing the impacts of the CBAM might hence have underestimated the consequences for developing and emerging economies.Accounting for rigidities in the production structure, we show that the CBAM may have a regressive impact, therefore requiring careful attention to its institutional design, especially if the objective is to reinforce global climate ambitions in line with the EU’s own decarbonisation strategy.Promoting the substitution of highly polluting technologies with green technologies seems notably easier in Europe than in EMDEs. Many jobs, tax revenues, and export revenues will be lost if the CBAM is implemented without taking into account the specificities of the EU’s trading partners.One possible way to minimise its side effects is to exempt the so-called least developed countries from the CBAM. Rather than an exemption, these countries could also receive targeted support from the EU to reduce their dependence on highly emitting industries, via transfer of technologies, climate subsidies, or concessional lending.The adoption of CBAM-like measures in other developed economies, such as Japan and North America, as well as in wealthier developing countries with the capacity to decarbonise their industries, such as China, would exacerbate the fragilities of emerging and developing economies unless counter-measures are taken. The CBAM is a logical complementary policy to the EU-ETS, which aims to avoid EU industries outsourcing their production to countries that do not adopt similar levels of carbon pricing. Although most macroeconomic models generally assume that all countries have a relatively high capacity to migrate from one industry to another, evidence shows otherwise. Previous results analysing the impacts of the CBAM might hence have underestimated the consequences for developing and emerging economies. Accounting for rigidities in the production structure, we show that the CBAM may have a regressive impact, therefore requiring careful attention to its institutional design, especially if the objective is to reinforce global climate ambitions in line with the EU’s own decarbonisation strategy. Promoting the substitution of highly polluting technologies with green technologies seems notably easier in Europe than in EMDEs. Many jobs, tax revenues, and export revenues will be lost if the CBAM is implemented without taking into account the specificities of the EU’s trading partners. One possible way to minimise its side effects is to exempt the so-called least developed countries from the CBAM. Rather than an exemption, these countries could also receive targeted support from the EU to reduce their dependence on highly emitting industries, via transfer of technologies, climate subsidies, or concessional lending. The adoption of CBAM-like measures in other developed economies, such as Japan and North America, as well as in wealthier developing countries with the capacity to decarbonise their industries, such as China, would exacerbate the fragilities of emerging and developing economies unless counter-measures are taken.
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- 2023
- Full Text
- View/download PDF
98. Delayed-onset post-craniotomy headache responsive to botulinum toxin A: a case series
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Ranoux, Danièle, Martiné, Gaëlle, Espagne, Gaëlle, Salle, Henri, and Caire, François
- Published
- 2017
- Full Text
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99. Reactant-induced photoactivation of in situ generated organogold intermediates leading to alkynylated indoles via Csp2-Csp cross-coupling
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Fen Zhao, Mehdi Abdellaoui, Wided Hagui, Maria Ballarin-Marion, Jérôme Berthet, Vincent Corcé, Stéphanie Delbaere, Héloïse Dossmann, Agathe Espagne, Jérémy Forté, Ludovic Jullien, Thomas Le Saux, Virginie Mouriès-Mansuy, Cyril Ollivier, Louis Fensterbank, Institut Parisien de Chimie Moléculaire (IPCM), Chimie Moléculaire de Paris Centre (FR 2769), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Lille Neurosciences & Cognition - U 1172 (LilNCog), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Département de Chimie - ENS Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Pigeon, Pascal, CHU Lille, Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) (PASTEUR), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), ESPAGNE, Agathe, ANR-17-CE07-0018,HyperSiLight,Utilisation de dérivés hypervalents du silicium en catalyse photoredox et duale(2017), and ANR-20-CE07-0038,LuxOr,Catalyse à l'or sous lumière visible(2020)
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Multidisciplinary ,[CHIM.ORGA]Chemical Sciences/Organic chemistry ,[CHIM] Chemical Sciences ,[CHIM]Chemical Sciences ,General Physics and Astronomy ,[CHIM.COOR]Chemical Sciences/Coordination chemistry ,General Chemistry ,[CHIM.COOR] Chemical Sciences/Coordination chemistry ,[CHIM.ORGA] Chemical Sciences/Organic chemistry ,General Biochemistry, Genetics and Molecular Biology - Abstract
Photosensitization of organogold intermediates is an emerging field in catalysis. In this context, an access to 2,3-disubstituted indoles from o-alkynyl aniline and iodoalkyne derivatives via a gold-catalyzed sequence under visible-light irradiation and in the absence of an exogenous photocatalyst was uncovered. A wide scope of the process is observed. Of note, 2-iodo-ynamides can be used as electrophiles in this cross-coupling reaction. The resulting N-alkynyl indoles lend themselves to post-functionalization affording valuable scaffolds, notably benzo[a]carbazoles. Mechanistic studies converge on the fact that a potassium sulfonyl amide generates emissive aggregates in the reaction medium. Static quenching of these aggregates by a vinylgold(I) intermediate yields to an excited state of the latter, which can react with an electrophile via oxidative addition and reductive elimination to forge the key C-C bond. This reactant-induced photoactivation of an organogold intermediate opens rich perspectives in the field of cross-coupling reactions.
- Published
- 2022
100. HP-HT Drilling Mud Based on Environmently-Friendly Fluorinated Chemicals
- Author
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Henaut I., Pasquier D., Rovinetti S., and Espagne B.
- Subjects
Chemical technology ,TP1-1185 ,Energy industries. Energy policy. Fuel trade ,HD9502-9502.5 - Abstract
The worldwide growing demand for energy drives oil and gas companies to drill deeper and hotter wells. The exploration and the development of Deeply Buried Reservoirs (DBR) generate major technical challenges due to the extremely high pressures and temperatures met (1 400 bar, 300°C). Currently, several drilling fluids are emerging. They are briefly reviewed at the beginning of the paper. The technical difficulty related to HP-HT mud is so significant that standard mud formulation technologies are irrelevant and alternative systems have to be considered. New formulations based on perfluorochemicals have been jointly developed by IFP Energies nouvelles (IFPEN), Solvay Specialty Polymers Italy and Total. Their lab characterizations are presented and reveal their promising benefits.
- Published
- 2015
- Full Text
- View/download PDF
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