51. MWASTools: an R/bioconductor package for metabolome-wide association studies.
- Author
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Rodriguez-Martinez A, Posma JM, Ayala R, Neves AL, Anwar M, Petretto E, Emanueli C, Gauguier D, Nicholson JK, and Dumas ME
- Subjects
- Genetic Association Studies, Humans, Metabolomics standards, Models, Biological, Quality Control, Metabolome, Metabolomics methods, Software
- Abstract
Summary: MWASTools is an R package designed to provide an integrated pipeline to analyse metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analysis using various models (partial correlations, generalized linear models); visualization of statistical outcomes; metabolite assignment using statistical total correlation spectroscopy (STOCSY); and biological interpretation of metabolome-wide association studies results., Availability and Implementation: The MWASTools R package is implemented in R (version > =3.4) and is available from Bioconductor: https://bioconductor.org/packages/MWASTools/., Contact: m.dumas@imperial.ac.uk., Supplementary Information: Supplementary data are available at Bioinformatics online., (© The Author(s) 2017. Published by Oxford University Press.)
- Published
- 2018
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