Search

Your search keyword '"Ding, Lin"' showing total 4,190 results
Start Over Author "Ding, Lin"
4,190 results on '"Ding, Lin"'

63. Field investigation combined with modeling uncovers the ecological heterogeneity of Aedes albopictus habitats for strategically improving systematic management during urbanization

Author

Guo, Xiang, Luo, Lei, Long, Yuxiang, Teng, Pingying, Wei, Yuehong, Xie, Tian, Li, Li, Yin, Qingqing, Li, Ziyao, Wang, Yuji, He, Jiejun, Ji, Xiatian, Zhou, Huasheng, Zhang, Xiaofan, Chen, Shigang, Zhou, Yezhen, Xu, Kaihui, Liang, Guancong, Kuang, Haocheng, Gao, Yuting, Liu, Xiaohua, Luo, Luting, Ding, Lin, Li, Yiji, Liu, Zhuanzhuan, Zhou, Tengfei, Lai, Zetian, Su, Xinghua, Guo, Yuyan, Li, Chenying, Xie, Lihua, Li, Minqing, Wu, Xinglong, Huang, Jianhao, Su, Weicong, Pan, Yicheng, Hu, Wei, Zhou, Dongrui, Li, Chunv, Gui, Juan, Ma, Jiazhi, Feng, Xiaoli, Zhu, Minyi, Zhong, Shangbin, Chen, Fan, Zeng, Huanchao, Wu, Yingxian, Wang, Chen, Li, Shukai, Wang, Qi, Wang, Xueyi, Zhou, Yekai, Ling, Jianxun, Liu, Yingjie, Wu, Shang, Li, Zhiwei, Zhong, Minghui, Wei, Wenxia, Xie, Lixian, Xu, Xianli, Huang, Hehai, Yang, Guilan, Liu, Yan, Liang, Siting, Wu, Yingxia, Zhang, Deyu, Xu, Changqing, Wang, Jie, Wang, Chunmei, Wu, Rangke, Yang, Zhicong, Chen, Xiao-Guang, and Zhou, Xiaohong

Published
2023
Full Text
View/download PDF

70. Functional regulation of microglia by vitamin B12 alleviates ischemic stroke-induced neuroinflammation in mice

Author

Yong Ge, Changjun Yang, Mojgan Zadeh, Shane M. Sprague, Yang-Ding Lin, Heetanshi Sanjay Jain, Brenden Fitzgerald Determann, II, William H. Roth, Juan Pablo Palavicini, Jonathan Larochelle, Eduardo Candelario-Jalil, and Mansour Mohamadzadeh

Subjects
Neuroscience, Immunology, Omics, Transcriptomics, Science
Abstract

Summary: Ischemic stroke is the second leading cause of death and disability worldwide, and efforts to prevent stroke, mitigate secondary neurological damage, and promote neurological recovery remain paramount. Recent findings highlight the critical importance of microbiome-related metabolites, including vitamin B12 (VB12), in alleviating toxic stroke-associated neuroinflammation. Here, we showed that VB12 tonically programmed genes supporting microglial cell division and activation and critically controlled cellular fatty acid metabolism in homeostasis. Intriguingly, VB12 promoted mitochondrial transcriptional and metabolic activities and significantly restricted stroke-associated gene alterations in microglia. Furthermore, VB12 differentially altered the functions of microglial subsets during the acute phase of ischemic stroke, resulting in reduced brain damage and improved neurological function. Pharmacological depletion of microglia before ischemic stroke abolished VB12-mediated neurological improvement. Thus, our preclinical studies highlight the relevance of VB12 in the functional programming of microglia to alleviate neuroinflammation, minimize ischemic injury, and improve host neurological recovery after ischemic stroke.

Published
2024
Full Text
View/download PDF

83. Monitoring urban ecosystem service value using dynamic multi-level grids

Author

Shao, Zhenfeng, Li, Yong, Huang, Xiao, Cai, Bowen, Ding, Lin, Pan, Wenkang, and Zhang, Ya

Subjects
Quantitative Biology - Populations and Evolution
Abstract

Ecosystem services are the direct and indirect contributions of an ecosystem to human well-being and survival. Ecosystem valuation is a method of assigning a monetary value to an ecosystem with its goods and services,often referred to as ecosystem service value (ESV). With the rapid expansion of cities, a mismatch occurs between urban development and ecological development, and it is increasingly urgent to establish a valid ecological assessment method. In this study, we propose an ecological evaluation standard framework by designing an ESV monitoring workflow based on the establishment of multi-level grids. The proposed method is able to capture multi-scale features, facilitates multi-level spatial expression, and can effectively reveal the spatial heterogeneity of ESV. Taking Haian city in the Jiangsu province as the study case, we implemented the proposed dynamic multi-level grids-based (DMLG) to calculate its urban ESV in 2016 and 2019. We found that the ESV of Haian city showed considerable growth (increased by 24.54 million RMB). Negative ESVs are concentrated in the central city, which presented a rapid trend of outward expansion. The results illustrated that the ongoing urban expanse does not reduce the ecological value in the study area. The proposed unified grid framework can be applied to other geographical regions and is expected to benefit future studies in ecosystem service evaluation in terms of capture multi-level spatial heterogeneity.

Published
2021

84. Rasch Measurement in Discipline-Based Physics Education Research

Author

Ding, Lin, Zeidler, Dana L., Series Editor, Bencze, John Lawrence, Editorial Board Member, Clough, Michael P., Editorial Board Member, Abd-El-Khalick, Fouad, Editorial Board Member, Rollnick, Marissa, Editorial Board Member, Sadler, Troy D., Editorial Board Member, Sjøeberg, Svein, Editorial Board Member, Treagust, David, Editorial Board Member, Yore, Larry D, Editorial Board Member, Liu, Xiufeng, editor, and Boone, William J., editor

Published
2023
Full Text
View/download PDF

85. Experimental Research on Ergonomics Evaluation of HMDs

Author

An, Kai, Wu, Xu, Miao, Chongchong, Ding, Lin, Sun, Guoqiang, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, and Duffy, Vincent G., editor

Published
2023
Full Text
View/download PDF

86. Experience Design for Multi-device Sharing Based on 3C Framework

Author

Wang, Kun, Huang, Bilan, Ding, Lin, Bu, Hanxu, Ge, Ying, Gu, Tingting, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Streitz, Norbert A., editor, and Konomi, Shin'ichi, editor

Published
2023
Full Text
View/download PDF

95. Disparities in the level of COVID-19 health literacy and the associated factors among employees in long-term care facilities in Taiwan

Author

Lan-Ping Lin, Jia-Rong Yu, and Jin-Ding Lin

Subjects
Coronavirus disease 2019 (COVID-19), Health literacy, Caregiving manpower, Elderly welfare agencies, Long-term care, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Coronavirus disease 2019 (COVID-19) poses a significant threat to the safety of residents in long-term care facilities, and the staff of long-term care facilities are essential in the care and prevention of major infectious diseases and therefore require good health literacy to ensure the health of residents. The main objective of this study was to examine the health literacy of staff in long-term care facilities and analyze the factors associated with their COVID-19 health literacy in Taiwan to provide a basis for the response mechanism to emerging infectious diseases. Methods A cross-sectional survey with a structured questionnaire by a convenience sample method and to assess the COVID-19 health literacy of caregivers working in long-term care facilities in this study. The COVID-19 health literacy scale was a self-administered scale designed to combine the concept of “health literacy” with the 3 levels and 5 stages of preventive medicine. A total of 385 workers from 10 long-term care facilities were surveyed as the study sample, and the validated questionnaires were statistically analyzed using SPSS version 22.0 statistical software. A multivariate logistic regression model was used to establish the associated factors of the COVID-19 health literacy level. Results Overall, the mean COVID-19 health literacy score was 88.7 ± 10.4 (range: 58–105). Using a quartile scale, 92 (23.9%) of the study participants had low health literacy (health literacy score 82 vs. ≤82) showed a significant difference in the study sample by gender (male vs. female, OR = 2.46, 95% CI = 1.15–5.26), job category (nurse practitioner vs. caregiver, OR = 7.25, 95% CI = 2.46–21.44), monthly service hours (> 160 h vs. 40–79 h, OR = 0.044, 95% CI = 0.07–0.97), experience caring for confirmed COVID-19 patients (yes vs. no, OR = 0.13, 95% CI = 0.02–0.98), and training related to infectious disease prevention and control (yes vs. no, OR = 2.8, 95% CI = 1.52–5.15). Conclusions This study recommends that facilities provide immediate updated COVID-19 information to staff, especially frontline caregivers, and specifically enhance COVID-19 infection control education training for all facility staff to eliminate health literacy disparities.

Published
2023
Full Text
View/download PDF

96. Co-infection of dengue and Zika viruses mutually enhances viral replication in the mosquito Aedes aegypti

Author

Daniel Chieh-Ding Lin, Shih-Che Weng, Po-Nien Tsao, Justin Jang Hann Chu, and Shin-Hong Shiao

Subjects
Aedes aegypti, Dengue virus, Zika virus, Co-infection, NS5 protein, Infectious and parasitic diseases, RC109-216
Abstract

Abstract Background The mosquito Aedes aegypti transmits two of the most serious mosquito-borne viruses, dengue virus (DENV) and Zika virus (ZIKV), which results in significant human morbidity and mortality worldwide. The quickly shifting landscapes of DENV and ZIKV endemicity worldwide raise concerns that their co-circulation through the Ae. aegypti mosquito vector could greatly exacerbate the disease burden in humans. Recent reports have indicated an increase in the number of co-infection cases in expanding co-endemic regions; however, the impact of co-infection on viral infection and the detailed molecular mechanisms remain to be defined. Methods C6/36 (Aedes albopictus) cells were cultured in Dulbecco's modified Eagle medium/Mitsuhashi and Maramorosch Insect Medium (DMEM/MM) (1:1) containing 2% heat-inactivated fetal bovine serum and 1× penicillin/streptomycin solution. For virus propagation, the cells were infected with either DENV serotype 2 (DENV2) strain 16681 or ZIKV isolate Thailand/1610acTw (MF692778.1). Mosquitoes (Ae. aegypti UGAL [University of Georgia Laboratory]/Rockefeller strain) were orally infected with DENV2 and ZIKV through infectious blood-feeding. Results We first examined viral replication activity in cells infected simultaneously, or sequentially, with DENV and ZIKV, and found interspecies binding of viral genomic transcripts to the non-structural protein 5 (NS5). When we challenged Ae. aegypti mosquitos with both DENV2 and ZIKV sequentially to probe similar interactions, virus production and vector susceptibility to infection were significantly enhanced. Conclusions Our results suggest that DENV2 and ZIKV simultaneously establishing infection in the Ae. aegypti mosquito vector may augment one another during replication. The data also implicate the homologous NS5 protein as a key intersection between the flaviviruses in co-infection, highlighting it as a potential target for vector control.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results