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54. 2013 WSES guidelines for management of intra-abdominal infections

Author

Sartelli, Massimo, Viale, Pierluigi, Catena, Fausto, Ansaloni, Luca, Moore, Ernest, Malangoni, Mark, Moore, Frederick A., Velmahos, George, Coimbra, Raul, Ivatury, Rao, Peitzman, Andrew, Koike, Kaoru, Leppäniemi, Ari, Biffl, Walter, Burlew, Clay Cothren, Balogh, Zsolt J., Boffard, Ken, Bendinelli, Cino, Gupta, Sanjay, Kluger, Yoram, Agresta, Ferdinando, Di Saverio, Salomone, Wani, Imtiaz, Escalona, Alex, Ordonez, Carlos, Fraga, Gustavo P., Pereira Junior, Gerson Alves, Bala, Miklosh, Cui, Yunfeng, Marwah, Sanjay, Sakakushev, Boris, Kong, Victor, Naidoo, Noel, Ahmed, Adamu, Abbas, Ashraf, Guercioni, Gianluca, Vettoretto, Nereo, Diaz-Nieto, Rafael, Gerych, Ihor, Trana, Cristian, Faro, Mario Paulo, Yuan, Kuo-Ching, Kok, Kenneth Yuh Yen, Mefire, Alain Chichom, Lee, Jae Gil, Hong, Suk-Kyung, Ghnnam, Wagih, Siribumrungwong, Boonying, Sato, Norio, Murata, Kiyoshi, Irahara, Takayuki, Coccolini, Federico, Segovia Lohse, Helmut A., Verni, Alfredo, Shoko, Tomohisa, and II kirurgian klinikka

Subjects
UNCOMPLICATED ACUTE APPENDICITIS, ANTIMICROBIAL RESISTANCE TRENDS, PERFORATED PEPTIC-ULCER, RANDOMIZED CONTROLLED-TRIALS, IMMEDIATE DEFINITIVE SURGERY, ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY, education, TYPHOID ILEAL PERFORATION, ACUTE CALCULOUS CHOLECYSTITIS, 3126 Surgery, anesthesiology, intensive care, radiology, DAMAGE CONTROL LAPAROTOMY, LAPAROSCOPIC PERITONEAL-LAVAGE
Published
2013

55. Complicated intra-abdominal infections in a worldwide context: an observational prospective study (CIAOW Study)

Author

Sartelli, Massimo, Catena, Fausto, Ansaloni, Luca, Moore, Ernest, Malangoni, Mark, Velmahos, George, Coimbra, Raul, Koike, Kaoru, Leppäniemi, Ari, Biffl, Walter, Balogh, Zsolt, Bendinelli, Cino, Gupta, Sanjay, Kluger, Yoram, Agresta, Ferdinando, di Saverio, Salomone, Tugnoli, Gregorio, Jovine, Elio, Ordonez, Carlos, Gomes, Carlos Augusto, Pereira Junior, Gerson Alves, Yuan, Kuo-Ching, Bala, Miklosh, Peev, Miroslav P., Cui, Yunfeng, Marwah, Sanjay, Zachariah, Sanoop, Sakakushev, Boris, Kong, Victor, Ahmed, Adamu, Abbas, Ashraf, Teixeira Gonsaga, Ricardo Alessandro, Guercioni, Gianluca, Vettoretto, Nereo, Poiasina, Elia, Ben-Ishay, Offir, Diaz-Nieto, Rafael, Massalou, Damien, Skrovina, Matej, Gerych, Ihor, Augustin, Goran, Kenig, Jakub, Khokha, Vladimir, Trana, Cristian, Kok, Kenneth Yuh Yen, Chichom Mefire, Alain, Lee, Jae Gil, Hong, Suk-Kyung, Segovia Lohse, Helmut Alfredo, Ghnnam, Wagih, Verni, Alfredo, Lohsiriwat, Varut, Siribumrungwong, Boonying, Tavares, Alberto, Baiocchi, Gianluca, Das, Koray, Jarry, Julien, Zida, Maurice, Sato, Norio, Murata, Kiyoshi, Shoko, Tomohisa, Irahara, Takayuki, Hamedelneel, Ahmed O., Naidoo, Noel, Adesunkanmi, Abdul Rashid Kayode, Kobe, Yoshiro, Attri, A. K., Sharma, Rajeev, Coccolini, Federico, El Zalabany, Tamer, Al Khalifa, Khalid, Sanjuan, Juan, Barnabe, Rita, Ishii, Wataru, and II kirurgian klinikka

Subjects
education, PERCUTANEOUS DRAINAGE, ABSCESSES, FLUID COLLECTIONS, RELAPAROTOMY, 3126 Surgery, anesthesiology, intensive care, radiology, SECONDARY PERITONITIS
Published
2013

56. Curative-intent treatment of recurrent colorectal liver metastases: A comparison between ablation and resection.

Author

Diaz-Nieto, Rafael, Fenwick, Stephen W., Poston, Graeme J., Malik, Hassan Z., Dupré, Aurélien, and Jones, Robert P.

Subjects
LIVER cancer, COLON cancer treatment, CURATIVE medicine, CATHETER ablation, SURGICAL excision, CANCER relapse, HEALTH outcome assessment
Abstract

Background Liver-limited recurrence after resection of colorectal liver metastases is a frequent occurrence, and can in some cases be treated with curative intent. Although surgical re-resection remains standard of care, there is growing interest in the role of ablation in this setting. The aim of this study was to compare the outcomes after curative-intent ablation and resection in patients with recurrent colorectal liver metastases. Methods We retrospectively analysed data from 366 consecutive patients who underwent liver resection for colorectal liver metastases between June 2010 and August 2015. Sixty-four developed liver-limited recurrence which was treated with curative intent, thirty-three (51.6%) by ablation and 31 (48.4%) by repeat resection. Results Patient groups were well matched, with surgically resected patients showing higher pre-operative carcinoembryonic antigen levels and larger metastases. There were fewer post-operative complications and shorter length of stay in the ablation group (p < 0.02). After a median follow-up of 36.2 months, median overall survival was the same for both the resected and ablated groups at 33.3 months. Median progression-free survival was longer for patients treated with surgery (10.2 months) compared to ablation (4.3 months) (p = 0.002). Conclusions Ablation or resection for liver-limited recurrence after surgery for colorectal liver metastases is associated with improved overall survival compared with systemic chemotherapy alone, and should always be considered for patients with resectable liver recurrence. Although ablation seemed to be associated with a shorter progression-free survival, post-procedure morbidity was significantly lower. The choice between ablation and resection should therefore be made on a personalised basis. [ABSTRACT FROM AUTHOR]

Published
2017
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61. Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study

Author

Sartelli, Massimo, Catena, Fausto, Ansaloni, Luca, Coccolini, Federico, Corbella, Davide, Moore, Ernest E, Malangoni, Mark, Velmahos, George, Coimbra, Raul, Koike, Kaoru, Leppaniemi, Ari, Biffl, Walter, Balogh, Zsolt, Bendinelli, Cino, Gupta, Sanjay, Kluger, Yoram, Agresta, Ferdinando, Saverio, Salomone Di, Tugnoli, Gregorio, Jovine, Elio, Ordonez, Carlos A, Whelan, James F, Fraga, Gustavo P, Gomes, Carlos Augusto, Pereira, Gerson Alves, Yuan, Kuo-Ching, Bala, Miklosh, Peev, Miroslav P, Ben-Ishay, Offir, Cui, Yunfeng, Marwah, Sanjay, Zachariah, Sanoop, Wani, Imtiaz, Rangarajan, Muthukumaran, Sakakushev, Boris, Kong, Victor, Ahmed, Adamu, Abbas, Ashraf, Gonsaga, Ricardo Alessandro Teixeira, Guercioni, Gianluca, Vettoretto, Nereo, Poiasina, Elia, Díaz-Nieto, Rafael, Massalou, Damien, Skrovina, Matej, Gerych, Ihor, Augustin, Goran, Kenig, Jakub, Khokha, Vladimir, Tranà, Cristian, Kok, Kenneth Yuh Yen, Mefire, Alain Chichom, Lee, Jae Gil, Hong, Suk-Kyung, Lohse, Helmut Alfredo Segovia, Ghnnam, Wagih, Verni, Alfredo, Lohsiriwat, Varut, Siribumrungwong, Boonying, El Zalabany, Tamer, Tavares, Alberto, Baiocchi, Gianluca, Das, Koray, Jarry, Julien, Zida, Maurice, Sato, Norio, Murata, Kiyoshi, Shoko, Tomohisa, Irahara, Takayuki, Hamedelneel, Ahmed O, Naidoo, Noel, Adesunkanmi, Abdul Rashid Kayode, Kobe, Yoshiro, Ishii, Wataru, Oka, Kazuyuki, Izawa, Yoshimitsu, Hamid, Hytham, Khan, Iqbal, Attri, AK, Sharma, Rajeev, Sanjuan, Juan, Badiel, Marisol, and Barnabé, Rita

Abstract

The CIAOW study (Complicated intra-abdominal infections worldwide observational study) is a multicenter observational study underwent in 68 medical institutions worldwide during a six-month study period (October 2012-March 2013). The study included patients older than 18 years undergoing surgery or interventional drainage to address complicated intra-abdominal infections (IAIs). 1898 patients with a mean age of 51.6 years (range 18-99) were enrolled in the study. 777 patients (41%) were women and 1,121 (59%) were men. Among these patients, 1,645 (86.7%) were affected by community-acquired IAIs while the remaining 253 (13.3%) suffered from healthcare-associated infections. Intraperitoneal specimens were collected from 1,190 (62.7%) of the enrolled patients. 827 patients (43.6%) were affected by generalized peritonitis while 1071 (56.4%) suffered from localized peritonitis or abscesses. The overall mortality rate was 10.5% (199/1898). According to stepwise multivariate analysis (PR = 0.005 and PE = 0.001), several criteria were found to be independent variables predictive of mortality, including patient age (OR = 1.1; 95%CI = 1.0-1.1; p < 0.0001), the presence of small bowel perforation (OR = 2.8; 95%CI = 1.5-5.3; p < 0.0001), a delayed initial intervention (a delay exceeding 24 hours) (OR = 1.8; 95%CI = 1.5-3.7; p < 0.0001), ICU admission (OR = 5.9; 95%CI = 3.6-9.5; p < 0.0001) and patient immunosuppression (OR = 3.8; 95%CI = 2.1-6.7; p < 0.0001).

Published
2014
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62. Complicated intra-abdominal infections in Europe: preliminary data from the first three months of the CIAO Study

Author

Sartelli, Massimo, Catena, Fausto, Ansaloni, Luca, Leppaniemi, Ari, Taviloglu, Korhan, Van Goor, Harry, Viale, Pierluigi, Lazzareschi, Daniel Vasco, De Werra, Carlo, Marrelli, Daniele, Colizza, Sergio, Scibé, Rodolfo, Alis, Halil, Torer, Nurkan, Navarro, Salvador, Catani, Marco, Kauhanen, Saila, Augustin, Goran, Sakakushev, Boris, Massalou, Damien, Pletinckx, Pieter, Kenig, Jakub, Di Saverio, Salomone, Guercioni, Gianluca, Rausei, Stefano, Laine, Samipetteri, Major, Piotr, Skrovina, Matej, Angst, Eliane, Pittet, Olivier, Gerych, Ihor, Tepp, Jaan, Weiss, Guenter, Vasquez, Giorgio, Vladov, Nikola, Tranà, Cristian, Vettoretto, Nereo, Delibegovic, Samir, Dziki, Adam, Giraudo, Giorgio, Pereira, Jorge, Poiasina, Elia, Tzerbinis, Helen, Hutan, Martin, Vereczkei, Andras, Krasniqi, Avdyl, Seretis, Charalampos, Diaz-Nieto, Rafael, Mesina, Cristian, Rems, Miran, Campanile, Fabio Cesare, Agresta, Ferdinando, Coletta, Pietro, Uotila-Nieminen, Mirjami, Dente, Mario, Bouliaris, Konstantinos, Lasithiotakis, Konstantinos, Khokha, Vladimir, Zivanović, Dragoljub, Smirnov, Dmitry, Marinis, Athanasios, Negoi, Ionut, Ney, Ludwig, Bini, Roberto, Leon, Miguel, Aloia, Sergio, Huchon, Cyrille, Moldovanu, Radu, De Melo, Renato Bessa, Giakoustidis, Dimitrios, Ioannidis, Orestis, Cucchi, Michele, Pintar, Tadeja, and Jovine, Elio

Subjects
3. Good health
Abstract

The CIAO Study is a multicenter observational study currently underway in 66 European medical institutions over the course of a six-month study period (January-June 2012).This preliminary report overviews the findings of the first half of the study, which includes all data from the first three months of the six-month study period.Patients with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study.912 patients with a mean age of 54.4 years (range 4-98) were enrolled in the study during the first three-month period. 47.7% of the patients were women and 52.3% were men. Among these patients, 83.3% were affected by community-acquired IAIs while the remaining 16.7% presented with healthcare-associated infections. Intraperitoneal specimens were collected from 64.2% of the enrolled patients, and from these samples, 825 microorganisms were collectively identified.The overall mortality rate was 6.4% (58/912). According to univariate statistical analysis of the data, critical clinical condition of the patient upon hospital admission (defined by severe sepsis and septic shock) as well as healthcare-associated infections, non-appendicular origin, generalized peritonitis, and serious comorbidities such as malignancy and severe cardiovascular disease were all significant risk factors for patient mortality.White Blood Cell counts (WBCs) greater than 12,000 or less than 4,000 and core body temperatures exceeding 38°C or less than 36°C by the third post-operative day were statistically significant indicators of patient mortality.

65. Incidence and risk factors for anastomotic bile leakage in hepatic resection with bilioenteric reconstruction - A international multicenter study

Author

Eva Braunwarth, Francesca Ratti, Luca Aldrighetti, Hasan A. Al-Saffar, Melroy A. D`Souza, Christian Sturesson, Richard Linke, Andreas Schnitzbauer, Martin Bodingbauer, Klaus Kaczirek, Daniel Vagg, Giles Toogood, Daniele Ferraro, Giuseppe K. Fusai, Rafael Diaz-Nieto, Hassan Malik, Frederik J.H. Hoogwater, Doris Wagner, Peter Kornprat, Ines Fischer, Reinhold Függer, Georg Göbel, Dietmar Öfner, Stefan Stättner, Braunwarth, Eva, Ratti, Francesca, Aldrighetti, Luca, Al-Saffar, Hasan A, D Souza, Melroy A, Sturesson, Christian, Linke, Richard, Schnitzbauer, Andrea, Bodingbauer, Martin, Kaczirek, Klau, Vagg, Daniel, Toogood, Gile, Ferraro, Daniele, Fusai, Giuseppe K, Diaz-Nieto, Rafael, Malik, Hassan, Hoogwater, Frederik J H, Wagner, Dori, Kornprat, Peter, Fischer, Ine, Függer, Reinhold, Göbel, Georg, Öfner, Dietmar, and Stättner, Stefan

Subjects
Hepatology, Gastroenterology
Abstract

Background: Anastomotic leak (AL) after bilioenteric reconstruction (BR) is a feared complication after bile duct resection, especially in combination with liver resection. Literature on surgical outcome is sparse. This study aimed to determine the incidence and risk factors for AL after combined liver and bile duct resection with a focus on operative or endoscopic reinterventions.Methods: Data from consecutive patients who underwent liver resection and BR between 2004 and 2018 in 11 academic institutions in Europe were collected from prospectively maintained databases.Results: Within 921 patients, AL rate was 5.4% with a 30d mortality of 9.6%. Pringle maneuver (pConclusion: This multicenter data provides the largest series to date of LR with BR and could help in the management of these patients which are often challenging and hampering the patients’ postoperative course negatively.

Published
2022

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