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73 results on '"DiGiovanni, Laura"'

53. Exercise-Induced Dose-Response Alterations in Adiponectin and Leptin Levels Are Dependent on Body Fat Changes in Women at Risk for Breast Cancer

Author

Sturgeon, Kathleen, primary, Digiovanni, Laura, additional, Good, Jerene, additional, Salvatore, Domenick, additional, Fenderson, Desiré, additional, Domchek, Susan, additional, Stopfer, Jill, additional, Galantino, Mary Lou, additional, Bryan, Cathy, additional, Hwang, Wei-Ting, additional, and Schmitz, Kathryn, additional

Published
2016
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56. Prospective registry of multiplex testing (PROMPT): A web-based platform to assess cancer risk of genetic variants.

Author

Walsh, Michael Francis, primary, Gaddam, Pragna, additional, Digiovanni, Laura, additional, Balmaña, Judith, additional, Dolinsky, Jill S, additional, Sittler, Taylor, additional, Klein, Rachel, additional, Lincoln, Stephen E, additional, Allen, Brian, additional, Leighton, Justin, additional, Strom, Charles, additional, Ranger-Miller, Vanessa, additional, Brown, Kyle, additional, Garber, Judy Ellen, additional, Couch, Fergus J., additional, Domchek, Susan M., additional, Robson, Mark E., additional, and Offit, Kenneth, additional

Published
2016
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57. Patient feedback and early outcome data with a novel tiered-binned model for multiplex breast cancer susceptibility testing

Author

Bradbury, Angela R., primary, Patrick-Miller, Linda J., additional, Egleston, Brian L., additional, DiGiovanni, Laura, additional, Brower, Jamie, additional, Harris, Diana, additional, Stevens, Evelyn M., additional, Maxwell, Kara N., additional, Kulkarni, Abha, additional, Chavez, Tyler, additional, Brandt, Amanda, additional, Long, Jessica M., additional, Powers, Jacquelyn, additional, Stopfer, Jill E., additional, Nathanson, Katherine L., additional, and Domchek, Susan M., additional

Published
2016
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58. Dose–response effects of aerobic exercise on estrogen among women at high risk for breast cancer: a randomized controlled trial

Author

Schmitz, Kathryn H., primary, Williams, Nancy I., additional, Kontos, Despina, additional, Domchek, Susan, additional, Morales, Knashawn H., additional, Hwang, Wei-Ting, additional, Grant, Lorita L., additional, DiGiovanni, Laura, additional, Salvatore, Domenick, additional, Fenderson, Desire’, additional, Schnall, Mitchell, additional, Galantino, Mary Lou, additional, Stopfer, Jill, additional, Kurzer, Mindy S., additional, Wu, Shandong, additional, Adelman, Jessica, additional, Brown, Justin C., additional, and Good, Jerene, additional

Published
2015
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59. Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility

Author

Bradbury, Angela R., primary, Patrick-Miller, Linda, additional, Long, Jessica, additional, Powers, Jacquelyn, additional, Stopfer, Jill, additional, Forman, Andrea, additional, Rybak, Christina, additional, Mattie, Kristin, additional, Brandt, Amanda, additional, Chambers, Rachelle, additional, Chung, Wendy K., additional, Churpek, Jane, additional, Daly, Mary B., additional, Digiovanni, Laura, additional, Farengo-Clark, Dana, additional, Fetzer, Dominique, additional, Ganschow, Pamela, additional, Grana, Generosa, additional, Gulden, Cassandra, additional, Hall, Michael, additional, Kohler, Lynne, additional, Maxwell, Kara, additional, Merrill, Shana, additional, Montgomery, Susan, additional, Mueller, Rebecca, additional, Nielsen, Sarah, additional, Olopade, Olufunmilayo, additional, Rainey, Kimberly, additional, Seelaus, Christina, additional, Nathanson, Katherine L., additional, and Domchek, Susan M., additional

Published
2015
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60. Interest in and outcomes with return of individual genetic research results for inherited susceptibility to breast cancer.

Author

Bradbury, Angela R., primary, Patrick-Miller, Linda J., additional, Egleston, Brian L., additional, Maxwell, Kara Noelle, additional, Brandt, Amanda, additional, Brower, Jamie, additional, Digiovanni, Laura, additional, Long, Jessica M., additional, Powers, Jacquelyn, additional, Stopfer, Jill, additional, Nathanson, Katherine L., additional, and Domchek, Susan M., additional

Published
2015
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62. Women In Steady Exercise Research (WISER) Sister: Study design and methods

Author

Schmitz, Kathryn H., primary, Williams, Nancy I., additional, Kontos, Despina, additional, Kurzer, Mindy S., additional, Schnall, Mitchell, additional, Domchek, Susan, additional, Stopfer, Jill, additional, Galantino, Mary Lou, additional, Hwang, Wei-Ting, additional, Morales, Knashawn, additional, Wu, Shandong, additional, DiGiovanni, Laura, additional, Salvatore, Domenick, additional, Fenderson, Desire', additional, Good, Jerene, additional, Sturgeon, Kathleen, additional, Grant, Lorita, additional, Bryan, Cathy J., additional, and Adelman, Jess, additional

Published
2015
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65. Adiponectin and Leptin are Not Positively Effected by Low Dose or High Dose Exercise Training

Author

Sturgeon, Kathleen M., primary, Adelman, Jessica, additional, DiGiovanni, Laura, additional, Salvatore, Domenick, additional, Fenderson, Desire’, additional, Good, Jerene, additional, Grant, Lorita, additional, Schnall, Mitchell, additional, Kontos, Despina, additional, Domcheck, Susan, additional, Stopfer, Jill Stopfer, additional, Galantino, Mary Lou, additional, Kurzer, Mindy, additional, Williams, Nancy, additional, Hwang, Wei-Ting, additional, Morales, Knashawn, additional, Wu, Shandong, additional, Bryan, Cathy J., additional, and Schmitz, Kathryn H., additional

Published
2014
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71. Impact of a Brief Touchscreen Based Modified Geriatric Assessment on the Care of Older Adults with Multiple Myeloma

Author

Nathwani, Nitya, Kurtin, Sandra, Lipe, Brea, Mohile, Supriya, Catamero, Donna D, Wildes, Tanya M., Wujcik, Debra, Davis, Agnes, Digiovanni, Laura, Stricker, Carrie T, and Hurria, Arti

Abstract

Background:Most adults (60%) diagnosed with Multiple Myeloma (MM) are > 65 years old (YO) and thus are at higher risk for toxicities of cancer treatment. Geriatric assessment (GA) can identify patients at risk for toxicity and morbidity more effectively than age or performance status, but is not easily integrated into a busy clinical setting. A technology assisted, modified GA (mGA) that includes the Palumbo frailty score can be used to summarize and report relevant clinical and self-reported symptom data to inform treatment decision making.

Published
2017
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72. A Case of Massive Hepatic Infarction in a Patient with HELLP Syndrome.

Author

Morgan J, Della Torre M, Whelan AR, Rodriguez SM, and DiGiovanni LM

Abstract

Background  Hepatic infarction is an exceedingly rare complication of hemolysis, elevated liver enzymes, and low platelets syndrome. Few cases have been described in the medical literature and the true incidence remains unknown. It can lead to fulminant liver failure, liver transplant, or death if not promptly addressed. Case Report  A 22-year-old primigravida presented with right upper quadrant and epigastric pain at 28 weeks' gestation. She had severely elevated blood pressures requiring intravenous antihypertensives as well as proteinuria, thrombocytopenia, and mild transaminitis. Within 6 hours of admission, her rapidly rising liver function tests (LFTs) necessitated urgent delivery by primary cesarean section. Her liver enzymes continued to rapidly worsen postoperatively and immediate postpartum computed tomography of the abdomen and pelvis revealed massive hepatic infarction, 11 × 10 × 15 cm, of the right lobe of the liver. Her transaminases peaked at alanine transferase of 2,863 IU/L and aspartate transferase of 2,732 IU/L. She received supportive multidisciplinary intensive care, and LFTs returned to normal by postoperative day 20. Conclusion  Hepatic infarction is an extraordinarily rare complication of pre-eclampsia. Early recognition and prompt multidisciplinary management are vital to prevent catastrophic bleeding, hepatic failure, and death.

Published
2019
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73. A hybrid effectiveness-implementation trial of an evidence-based exercise intervention for breast cancer survivors.

Author

Beidas RS, Paciotti B, Barg F, Branas AR, Brown JC, Glanz K, DeMichele A, DiGiovanni L, Salvatore D, and Schmitz KH

Subjects
Adult, Aged, Body Image, Breast Neoplasms physiopathology, Breast Neoplasms psychology, Evidence-Based Medicine, Exercise physiology, Exercise psychology, Female, Humans, Integrative Medicine economics, Middle Aged, Muscle Strength, Muscle, Skeletal physiology, Patient Selection, Program Development, Program Evaluation, Referral and Consultation, Attitude of Health Personnel, Breast Neoplasms rehabilitation, Integrative Medicine organization & administration, Lymphedema therapy, Resistance Training adverse effects, Resistance Training economics, Resistance Training organization & administration, Survivors psychology
Abstract

Background: The primary aims of this hybrid Type 1 effectiveness-implementation trial were to quantitatively assess whether an evidence-based exercise intervention for breast cancer survivors, Strength After Breast Cancer, was safe and effective in a new setting and to qualitatively assess barriers to implementation., Methods: A cohort of 84 survivors completed measurements related to limb volume, muscle strength, and body image at baseline, 67 survivors completed measurements 12 months later. Qualitative methods were used to understand barriers to implementation experienced by referring oncology clinicians and physical therapists who delivered the program., Results: Similar to the efficacy trial, the revised intervention demonstrated safety with regard to lymphedema, and led to improvements in lymphedema symptoms, muscular strength, and body image. Comparison of effects in the effectiveness trial to effects in the efficacy trial revealed larger strength increases in the efficacy trial than in the effectiveness trial (P < .04), but few other differences were found. Qualitative implementation data suggested significant barriers around intervention characteristics, payment, eligibility criteria, the referral process, the need for champions (ie, advocates), and the need to adapt during implementation of the intervention, which should be considered in future dissemination and implementation efforts., Conclusions: This trial successfully demonstrated that a physical therapy led strength training program for breast cancer survivors can be implemented in a community setting while retaining the effectiveness and safety of the clinical trial. However, during the translation process, strategies to reduce barriers to implementation are required. This new program can inform larger scale dissemination and implementation efforts., (© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.)

Published
2014
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