570 results on '"Dhana, Klodian"'
Search Results
52. Different associations of varying types of Vitamin E and cognitive function in older adults with or without APOE Ɛ4 allele
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Liu, Xiaoran, primary, Beck, Todd, additional, Dhana, Klodian, additional, Evans, Denis A, additional, and Rajan, Kumar B, additional
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- 2022
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53. Racial Differences in the Association of MIND Diet/Physical Activity Combinations and Cognition in older adults
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Holland, Thomas Monroe, primary, Agarwal, Puja, additional, Dhana, Klodian, additional, Desai, Pankaja, additional, Liu, Xiaoran, additional, Krueger, Kristin R, additional, Beck, Todd, additional, Cherian, Laurel J, additional, Schneider, Julie A, additional, Aggarwal, Neelum T., additional, Barnes, Lisa L., additional, and Rajan, Kumar B, additional
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- 2022
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54. Mediterranean-DASH Intervention for Neurodegenerative Delay diet and risk of dementia: three prospective studies and meta-analysis of cohort studies
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Chen, Hui, primary, Dhana, Klodian, additional, Huang, Yuhui, additional, Huang, Liyan, additional, Tao, Yang, additional, Liu, Xiaoran, additional, van Lent, Debora Melo, additional, Zheng, Yan, additional, Ascherio, Alberto, additional, Willett, Walter, additional, and Yuan, Changzheng, additional
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- 2022
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55. The challenge of pre-enrollment selection bias in estimating the effects of air pollution on cognitive decline and other dementia-related outcomes
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Andrews, Ryan, primary, Adar, Sara D., additional, Kaufman, Joel D., additional, Christopher, Cami, additional, Beck, Todd, additional, Rajan, Kumar B., additional, Dhana, Klodian, additional, Evans, Denis, additional, and Weuve, Jennifer, additional
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- 2022
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56. Lifestyle and Cognitive Decline in Community-Dwelling Stroke Survivors
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Dhana, Klodian, primary, Aggarwal, Neelum T., additional, Beck, Todd, additional, Holland, Thomas M., additional, Dhana, Anisa, additional, Cherian, Laurel J., additional, Desai, Pankaja, additional, Evans, Denis A., additional, and Rajan, Kumar B., additional
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- 2022
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57. Antioxidants and risk of dementia: recent insights and future opportunities
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Koch, Manja, Dhana, Klodian, and Jensen, Majken K.
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- 2018
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58. Impact of Healthy Lifestyle Factors on Life Expectancies in the US Population
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Li, Yanping, Pan, An, Wang, Dong D., Liu, Xiaoran, Dhana, Klodian, Franco, Oscar H., Kaptoge, Stephen, Di Angelantonio, Emanuele, Stampfer, Meir, Willett, Walter C., and Hu, Frank B.
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- 2018
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59. Exposure to perchlorate, nitrate and thiocyanate, and prevalence of diabetes mellitus
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Liu, Gang, Zong, Geng, Dhana, Klodian, Hu, Yang, Blount, Benjamin C, Morel-Espinosa, Maria, and Sun, Qi
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- 2017
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60. Risk Prediction Models of Natural Menopause Onset: A Systematic Review
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Raeisi-Dehkordi, Hamidreza, primary, Kummer, Stefanie, additional, Francis Raguindin, Peter, additional, Dejanovic, Gordana, additional, Eylul Taneri, Petek, additional, Cardona, Isabel, additional, Kastrati, Lum, additional, Minder, Beatrice, additional, Voortman, Trudy, additional, Marques-Vidal, Pedro, additional, Dhana, Klodian, additional, Glisic, Marija, additional, and Muka, Taulant, additional
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- 2022
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61. Vitamin D intake and cognitive decline in Blacks and Whites: The role of diet and supplements
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Dhana, Klodian, primary, Barnes, Lisa L., additional, Agarwal, Puja, additional, Liu, Xiaoran, additional, Dhana, Anisa, additional, Desai, Pankaja, additional, Aggarwal, Neelum, additional, Evans, Denis A., additional, and Rajan, Kumar B., additional
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- 2022
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62. Association of Whole Grain Consumption and Cognitive Function in Biracial Population Sample
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Liu, Xiaoran, primary, Beck, Todd, additional, Dhana, Klodian, additional, Agarwal, Puja, additional, Tangney, Christy, additional, Evans, Denis, additional, and Rajan, Kumar, additional
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- 2022
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63. Racial Differences in the Association of Fruit and Vegetable Intake With Cognitive Decline
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Agarwal, Puja, primary, Beck, Todd, additional, Dhana, Klodian, additional, Liu, Xiaoran, additional, Rajan, Kumar, additional, Tangney, Christy, additional, Zhang, Yanyu, additional, and Barnes, Lisa, additional
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- 2022
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64. Abstract 20397: The Impact of Healthy Lifestyle on Life Expectancy in the U.S. Population
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Li, Yanping, Pan, An, Wang, Dong D, Liu, Xiaoran, Dhana, Klodian, Franco, Oscar H, Kaptoge, Stephen, Angelantonio, Emanuele D, Stampfer, Meir, Walter, Willett C, and Hu, Frank B
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- 2017
65. Association of Thyroid Function With Life Expectancy With and Without Cardiovascular Disease: The Rotterdam Study
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Bano, Arjola, Dhana, Klodian, Chaker, Layal, Kavousi, Maryam, Ikram, M. Arfan, Mattace-Raso, Francesco U. S., Peeters, Robin P., and Franco, Oscar H.
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- 2017
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66. Vitamin D intake and cognitive decline in Blacks and Whites: The role of diet and supplements.
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Dhana, Klodian, Barnes, Lisa L., Agarwal, Puja, Liu, Xiaoran, Dhana, Anisa, Desai, Pankaja, Aggarwal, Neelum, Evans, Denis A., and Rajan, Kumar B.
- Abstract
Introduction: To determine the role of vitamin D intake on cognitive decline among Blacks and Whites. Methods: Using data from the population‐based Chicago Health and Aging Project, we studied 2061 Blacks and 1329 Whites with dietary vitamin D data and cognitive testing over 12 years of follow‐up. Multivariable linear mixed‐effects models were used to determine the association of vitamin D intake with cognitive decline. Results: Vitamin D intake, particularly dietary vitamin D, was associated with a slower rate of decline in cognitive function among Blacks. In Blacks, comparing individuals in the lowest tertile of dietary intake, those in the highest tertile had a slower cognitive decline of 0.017 units/year (95% confidence interval 0.006, 0.027), independently of supplementation use. In Whites, vitamin D intake was not associated with cognitive decline. Discussion: Dietary vitamin D may help to slow the decline in cognitive abilities among Blacks as they age. [ABSTRACT FROM AUTHOR]
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- 2023
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67. Association of Subjective Memory Complaints With White Matter Hyperintensities and Cognitive Decline Among Older Adults in Chicago, Illinois
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Dhana, Anisa, primary, DeCarli, Charles, additional, Dhana, Klodian, additional, Desai, Pankaja, additional, Krueger, Kristin, additional, Evans, Denis A., additional, and Rajan, Kumar B., additional
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- 2022
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68. Healthy lifestyle and life expectancy with and without Alzheimer’s dementia: population based cohort study
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Dhana, Klodian, primary, Franco, Oscar H, additional, Ritz, Ethan M, additional, Ford, Christopher N, additional, Desai, Pankaja, additional, Krueger, Kristin R, additional, Holland, Thomas M, additional, Dhana, Anisa, additional, Liu, Xiaoran, additional, Aggarwal, Neelum T, additional, Evans, Denis A, additional, and Rajan, Kumar B, additional
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- 2022
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69. Examination of Neurofilament Light Chain Serum Concentrations, Physical Activity, and Cognitive Decline in Older Adults
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Desai, Pankaja, primary, Dhana, Klodian, additional, DeCarli, Charles, additional, Wilson, Robert S., additional, McAninch, Elizabeth A., additional, Evans, Denis A., additional, and Rajan, Kumar B., additional
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- 2022
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70. Abstract 066: A Healthy Plant-based Diet Was Associated With Slower Cognitive Decline In African Americans: A Biracial Community-based Cohort Of Older Adults
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Liu, Xiaoran, primary, Dhana, Klodian, additional, Barnes, Lisa, additional, Tangney, Christy, additional, Aggarwal, Puja, additional, Agarwal, Neelum, additional, Holland, Thomas, additional, and Rajan, Kumar, additional
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- 2022
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71. Association of a Healthy Lifestyle With All-Cause and Cause-Specific Mortality Among Individuals With Type 2 Diabetes: A Prospective Study in UK Biobank
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Han, Han, primary, Cao, Yaying, primary, Feng, Chengwu, primary, Zheng, Yan, primary, Dhana, Klodian, primary, Zhu, Shu, primary, Shang, Cong, primary, Yuan, Changzheng, primary, and Zong, Geng, primary
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- 2021
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72. Properties of the cognitive function battery for the MIND diet intervention to prevent Alzheimer’s disease
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Krueger, Kristin R., primary, Dhana, Klodian, additional, Aggarwal, Neelum T., additional, Arfanakis, Konstantinos, additional, Carey, Vincent, additional, Sacks, Frank, additional, and Barnes, Lisa L., additional
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- 2021
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73. Effects of the MIND diet and physical activity on cognitive domains in the elderly
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Holland, Thomas Monroe, primary, Agarwal, Puja, additional, Dhana, Klodian, additional, Halloway, Shannon, additional, Desai, Pankaja, additional, Wang, Yamin, additional, Aggarwal, Neelum T, additional, Barnes, Lisa L, additional, and Rajan, Kumar B, additional
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- 2021
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74. Healthy lifestyle, brain pathology, and cognition in community‐dwelling older adults
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Dhana, Klodian, primary, James, Bryan D, additional, Leurgans, Sue E., additional, Rajan, Kumar B, additional, Aggarwal, Neelum T, additional, Barnes, Lisa L, additional, Bennett, David A, additional, and Schneider, Julie A, additional
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- 2021
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75. Healthy lifestyle and cognitive decline in people living with stroke in the community
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Dhana, Klodian, primary, Aggarwal, Neelum T, additional, Beck, Todd, additional, Desai, Pankaja, additional, Liu, Xiaoran, additional, Barnes, Lisa L, additional, Evans, Denis A, additional, and Rajan, Kumar B, additional
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- 2021
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76. Trajectories of cognitive activity from early to late life and risk of Alzheimer’s dementia in community‐dwelling older adults
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Dhana, Klodian, primary, Rajan, Kumar B, additional, Zammit, Andrea R, additional, Wilson, Robert S, additional, Liu, Xiaoran, additional, Aggarwal, Neelum T, additional, Leurgans, Sue E, additional, Bennett, David A, additional, and Barnes, Lisa L, additional
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- 2021
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77. MIND and Mediterranean diet association with Alzheimer’s disease pathology
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Agarwal, Puja, primary, Wang, Yamin, additional, Aggarwal, Neelum T, additional, Cherian, Laurel J, additional, James, Bryan D, additional, Dhana, Klodian, additional, Leurgans, Sue E, additional, Bennett, David A, additional, and Schneider, Julie A, additional
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- 2021
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78. Plant‐based dietary patterns and cognitive function in U.S. adults: A prospective evaluation
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Liu, Xiaoran, primary, Wang, Yamin, additional, Dhana, Klodian, additional, Agarwal, Puja, additional, Cherian, Laurel J, additional, Bennett, David A., additional, Schneider, Julie A., additional, and Aggarwal, Neelum T., additional
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- 2021
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79. Longitudinal evaluation of total tau and physical activity on cognitive decline in a population‐based study
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Desai, Pankaja, primary, Evans, Denis A., additional, Dhana, Klodian, additional, Aggarwal, Neelum T., additional, Wilson, Robert S., additional, and Rajan, Kumar B., additional
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- 2021
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80. Physical Activity Types and Coronary Heart Disease Risk in Middle-Aged and Elderly Persons: The Rotterdam Study
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Koolhaas, Chantal M., Dhana, Klodian, Golubic, Rajna, Schoufour, Josje D., Hofman, Albert, van Rooij, Frank J. A., and Franco, Oscar H.
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- 2016
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81. Association of Dietary Intake of Flavonols With Changes in Global Cognition and Several Cognitive Abilities.
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Holland, Thomas Monroe, Agarwal, Puja, Wang, Yamin, Dhana, Klodian, Leurgans, Sue E., Shea, Kyla, Booth, Sarah L., Rajan, Kumar B., Schneider, Julie A., and Barnes, Lisa L.
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- 2023
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82. Abstract 13759: Adherence to Healthy Lifestyle is Associated With Lower Total and Cause-Specific Mortality Risk Among Patients With Diabetes: The UK Biobank Study
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Han, Han, primary, Cao, Yaying, additional, Feng, Chengwu, additional, zheng, yan, additional, Dhana, Klodian, additional, Zhu, Shu, additional, Shang, Cong, additional, Yuan, Changzheng, additional, and Zong, Geng, additional
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- 2021
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83. Abstract 13245: Cardiovascular Risk Burden in Relation to Dementia and Brain Structural Imaging Markers: A Study From UK Biobank
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Cao, Yaying, primary, Feng, Chengwu, additional, Chen, Jing, additional, Gan, Wei, additional, Ma, Yuan, additional, Hu, Yonghua, additional, Dhana, Klodian, additional, Shen, Jie, additional, zheng, yan, additional, Yuan, Changzheng, additional, and Zong, Geng, additional
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- 2021
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84. MIND Diet, Common Brain Pathologies, and Cognition in Community-Dwelling Older Adults
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Dhana, Klodian, primary, James, Bryan D., additional, Agarwal, Puja, additional, Aggarwal, Neelum T., additional, Cherian, Laurel J., additional, Leurgans, Sue E., additional, Barnes, Lisa L., additional, Bennett, David A., additional, and Schneider, Julie A., additional
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- 2021
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85. Vitamin D Intake and Brain Cortical Thickness in Community-Dwelling Overweight Older Adults: A Cross-Sectional Study
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Lefèvre-Arbogast, Sophie, primary, Dhana, Klodian, additional, Aggarwal, Neelum T, additional, Zhang, Shengwei, additional, Agarwal, Puja, additional, Liu, Xiaoran, additional, Laranjo, Nancy, additional, Carey, Vincent, additional, Sacks, Frank, additional, Barnes, Lisa L, additional, and Arfanakis, Konstantinos, additional
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- 2021
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86. Perfluoroalkyl substances and changes in body weight and resting metabolic rate in response to weight-loss diets: A prospective study
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Liu, Gang, Dhana, Klodian, Furtado, Jeremy D., Rood, Jennifer, Zong, Geng, Liang, Liming, Qi, Lu, Bray, George A., DeJonge, Lilian, Coull, Brent, Grandjean, Philippe, and Sun, Qi
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Reducing diets -- Health aspects ,Alkyl groups -- Physiological aspects -- Health aspects ,Body weight -- Measurement ,Biological sciences - Abstract
Background The potential endocrine-disrupting effects of perfluoroalkyl substances (PFASs) have been demonstrated in animal studies, but whether PFASs may interfere with body weight regulation in humans is largely unknown. This study aimed to examine the associations of PFAS exposure with changes in body weight and resting metabolic rate (RMR) in a diet-induced weight-loss setting. Methods and findings In the 2-year POUNDS Lost randomized clinical trial based in Boston, Massachusetts, and Baton Rouge, Louisiana, that examined the effects of energy-restricted diets on weight changes, baseline plasma concentrations of major PFASs were measured among 621 overweight and obese participants aged 30-70 years. Body weight was measured at baseline and 6, 12, 18, and 24 months. RMR and other metabolic parameters, including glucose, lipids, thyroid hormones, and leptin, were measured at baseline and 6 and 24 months. Participants lost an average of 6.4 kg of body weight during the first 6 months (weight-loss period) and subsequently regained an average of 2.7 kg of body weight during the period of 6-24 months (weight regain period). After multivariate adjustment, baseline PFAS concentrations were not significantly associated with concurrent body weight or weight loss during the first 6 months. In contrast, higher baseline levels of PFASs were significantly associated with a greater weight regain, primarily in women. In women, comparing the highest to the lowest tertiles of PFAS concentrations, the multivariate-adjusted mean weight regain (SE) was 4.0 (0.8) versus 2.1 (0.9) kg for perfluorooctanesulfonic acid (PFOS) (P.sub.trend = 0.01); 4.3 (0.9) versus 2.2 (0.8) kg for perfluorooctanoic acid (PFOA) (P.sub.trend = 0.007); 4.7 (0.9) versus 2.5 (0.9) kg for perfluorononanoic acid (PFNA) (P.sub.trend = 0.006); 4.9 (0.9) versus 2.7 (0.8) kg for perfluorohexanesulfonic acid (PFHxS) (P.sub.trend = 0.009); and 4.2 (0.8) versus 2.5 (0.9) kg for perfluorodecanoic acid (PFDA) (P.sub.trend = 0.03). When further adjusted for changes in body weight or thyroid hormones during the first 6 months, results remained similar. Moreover, higher baseline plasma PFAS concentrations, especially for PFOS and PFNA, were significantly associated with greater decline in RMR during the weight-loss period and less increase in RMR during the weight regain period in both men and women. Limitations of the study include the possibility of unmeasured or residual confounding by socioeconomic and psychosocial factors, as well as possible relapse to the usual diet prior to randomization, which could have been rich in foods contaminated by PFASs through food packaging and also dense in energy. Conclusions In this diet-induced weight-loss trial, higher baseline plasma PFAS concentrations were associated with a greater weight regain, especially in women, possibly explained by a slower regression of RMR levels. These data illustrate a potential novel pathway through which PFASs interfere with human body weight regulation and metabolism. The possible impact of environmental chemicals on the obesity epidemic therefore deserves attention. Trial registration ClinicalTrials.gov NCT00072995, Author(s): Gang Liu 1, Klodian Dhana 1, Jeremy D. Furtado 1, Jennifer Rood 2, Geng Zong 1, Liming Liang 3,4, Lu Qi 5, George A. Bray 2, Lilian DeJonge 2, [...]
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- 2018
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87. Anthropometric measures in cardiovascular disease prediction: comparison of laboratory-based versus non-laboratory-based model
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Dhana, Klodian, Ikram, M Arfan, Hofman, Albert, Franco, Oscar H, and Kavousi, Maryam
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- 2015
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88. healthy plant-based diet was associated with slower cognitive decline in African American older adults: a biracial community-based cohort.
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Liu, Xiaoran, Dhana, Klodian, Barnes, Lisa L, Tangney, Christy C, Agarwal, Puja, Aggarwal, Neelum, Holland, Thomas M, Beck, Todd, Evans, Denis A, and Rajan, Kumar B
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FOOD habits ,RACE ,SENSORY perception ,PLANT-based diet ,QUALITY assurance ,EPISODIC memory ,INDEPENDENT living ,COGNITIVE testing ,AFRICAN Americans ,LONGITUDINAL method ,OLD age - Abstract
Background African American (AA) adults have about twice the risk of developing dementia compared with white adults. However, evidence on dietary modification in preventing cognitive decline from diverse populations focusing on AA adults is minimal. Objectives We aimed to evaluate the association between a plant-based diet and the rate of cognitive decline in a population-based sample of AA and white adults. Methods This study consisted of 3337 participants from the Chicago Health and Aging Project (60% AA participants, 64% female). Plant-based diet quality was evaluated by the overall plant-based diet index (PDI), the healthful PDI (hPDI), and the unhealthful PDI (uPDI). Global cognition was assessed using a composite score of 4 individual tests of cognition. We used mixed models to examine the associations of PDI, hPDI, and uPDI with the rates of decline in global cognition, perceptual speed, and episodic memory. Models were adjusted for age, sex, presence of apoE e4 allele, lifestyle factors including education, cognitive activities, smoking status, calorie intake, risk factors for cardiovascular disease, time, and the interaction terms of time × each covariate. Results AA and white participants had various dietary patterns. Higher hPDI was associated with a slower rate of decline in global cognition, perceptual speed, and episodic memory in AA participants but not white participants. AA study participants in the highest quintile of hPDI had significantly slower rates of global cognitive decline (β: 0.0183 ± 0.0086; P = 0.032), perceptual speed (β: 0.0179 ± 0.0088; P = 0.04), and episodic memory (β: 0.0163 ± 0.0118; P = 0.04) than individuals in the lowest quintile of hPDI. There were no associations of either PDI or uPDI with the rate of cognitive decline in either racial group. Conclusions A healthy plant-based diet was associated with a slower rate of decline in global cognition, perceptual speed, and episodic memory in AA adults. [ABSTRACT FROM AUTHOR]
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- 2022
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89. Properties of the Cognitive Function Battery for the MIND Diet Intervention to Prevent Alzheimer's Disease.
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Krueger, Kristin R., Dhana, Klodian, Aggarwal, Neelum T., Arfanakis, Konstantinos, Carey, Vincent J., Sacks, Frank M., and Barnes, Lisa L.
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ALZHEIMER'S disease , *COGNITIVE ability , *COGNITION , *PRINCIPAL components analysis , *EPISODIC memory , *SEMANTIC memory , *EXECUTIVE function - Abstract
Objective: To evaluate the properties of the cognitive battery used in the MIND Diet Intervention to Prevent Alzheimer's Disease. The MIND Diet Intervention is a randomized control trial to determine the relative effectiveness of the MIND diet in slowing cognitive decline and reducing brain atrophy in older adults at risk for Alzheimer's dementia. Methods: The MIND cognitive function battery was administered at baseline to 604 participants of an average age of 70 years, who agreed to participate in the diet intervention study, and was designed to measure change over time. The battery included 12 cognitive tests, measuring the 4 cognitive domains of executive function, perceptual speed, episodic memory, and semantic memory. We conducted a principal component analysis to examine the consistency between our theoretical domains and the statistical performance of participants in each domain. To further establish the validity of each domain, we regressed the domain scores against a late-life cognitive activity score, controlling for age, race, sex, and years of education. Results: Four factors emerged in the principal component analyses that were similar to the theoretical domains. In regression equations, we found the expected associations with age, education, and late-life cognitive activity with each of the four cognitive domains. Conclusions: These results indicate that the MIND cognitive battery is a comprehensive and valid battery of four separate domains of cognitive function that can be used in diet intervention trials for older adults. [ABSTRACT FROM AUTHOR]
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- 2022
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90. Longitudinal Association of Total Tau Concentrations and Physical Activity With Cognitive Decline in a Population Sample
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Desai, Pankaja, primary, Evans, Denis, additional, Dhana, Klodian, additional, Aggarwal, Neelum T., additional, Wilson, Robert S., additional, McAninch, Elizabeth, additional, and Rajan, Kumar B., additional
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- 2021
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91. Genetic risk, adherence to a healthy lifestyle, and cognitive decline in African Americans and European Americans
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Dhana, Klodian, primary, Barnes, Lisa L., additional, Liu, Xiaoran, additional, Agarwal, Puja, additional, Desai, Pankaja, additional, Krueger, Kristin R., additional, Holland, Thomas M., additional, Halloway, Shannon, additional, Aggarwal, Neelum T., additional, Evans, Denis A., additional, and Rajan, Kumar B., additional
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- 2021
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92. Higher Plasma α-Carotene Was Associated With Better Cognitive Function: A Cross-Sectional Evaluation Among the MIND Trial Participants
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Liu, Xiaoran, primary, Dhana, Klodian, additional, Furtado, Jeremy, additional, Agarwal, Puja, additional, Aggarwal, Neelum, additional, Tangney, Christy, additional, Laranjo, Nancy, additional, Carey, Vincent, additional, Barnes, Lisa, additional, and Sacks, Frank, additional
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- 2021
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93. A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
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Jhun, Mina-A, Mendelson, Michael, Wilson, Rory, Gondalia, Rahul, Joehanes, Roby, Salfati, Elias, Zhao, Xiaoping, Braun, Kim Valeska Emilie, Do, Anh Nguyet, Hedman, Åsa K, Zhang, Tao, Carnero-Montoro, Elena, Shen, Jincheng, Bartz, Traci M., Brody, Jennifer A., Montasser, May E., O'Connell, Jeff R., Yao, Chen, Xia, Rui, Boerwinkle, Eric, Grove, Megan, Guan, Weihua, Liliane, Pfeiffer, Singmann, Paula, Mueller-Nurasyid, Martina, Meitinger, Thomas, Gieger, Christian, Peters, Annette, Zhao, Wei, Ware, Erin B., Smith, Jennifer A., Dhana, Klodian, van Meurs, Joyce, Uitterlinden, Andre, Ikram, Mohammad Arfan, Ghanbari, Mohsen, Zhi, Deugi, Gustafsson, Stefan, Lind, Lars, Li, Shengxu, Sun, Dianjianyi, Spector, Tim D., Chen, Yii-der Ida, Damcott, Coleen, Shuldiner, Alan R., Absher, Devin M., Horvath, Steve, Tsao, Philip S., Kardia, Sharon, Psaty, Bruce M., Sotoodehnia, Nona, Bell, Jordana T., Ingelsson, Erik, Chen, Wei, Dehghan, Abbas, Arnett, Donna K., Waldenberger, Melanie, Hou, Lifang, Whitsel, Eric A., Baccarelli, Andrea, Levy, Daniel, Fornage, Myriam, Irvin, Marguerite R., Assimes, Themistocles L., Jhun, Mina-A, Mendelson, Michael, Wilson, Rory, Gondalia, Rahul, Joehanes, Roby, Salfati, Elias, Zhao, Xiaoping, Braun, Kim Valeska Emilie, Do, Anh Nguyet, Hedman, Åsa K, Zhang, Tao, Carnero-Montoro, Elena, Shen, Jincheng, Bartz, Traci M., Brody, Jennifer A., Montasser, May E., O'Connell, Jeff R., Yao, Chen, Xia, Rui, Boerwinkle, Eric, Grove, Megan, Guan, Weihua, Liliane, Pfeiffer, Singmann, Paula, Mueller-Nurasyid, Martina, Meitinger, Thomas, Gieger, Christian, Peters, Annette, Zhao, Wei, Ware, Erin B., Smith, Jennifer A., Dhana, Klodian, van Meurs, Joyce, Uitterlinden, Andre, Ikram, Mohammad Arfan, Ghanbari, Mohsen, Zhi, Deugi, Gustafsson, Stefan, Lind, Lars, Li, Shengxu, Sun, Dianjianyi, Spector, Tim D., Chen, Yii-der Ida, Damcott, Coleen, Shuldiner, Alan R., Absher, Devin M., Horvath, Steve, Tsao, Philip S., Kardia, Sharon, Psaty, Bruce M., Sotoodehnia, Nona, Bell, Jordana T., Ingelsson, Erik, Chen, Wei, Dehghan, Abbas, Arnett, Donna K., Waldenberger, Melanie, Hou, Lifang, Whitsel, Eric A., Baccarelli, Andrea, Levy, Daniel, Fornage, Myriam, Irvin, Marguerite R., and Assimes, Themistocles L.
- Abstract
Here we examine the association between DNA methylation in circulating leukocytes and blood lipids in a multi-ethnic sample of 16,265 subjects. We identify 148, 35, and 4 novel associations among Europeans, African Americans, and Hispanics, respectively, and an additional 186 novel associations through a trans-ethnic meta-analysis. We observe a high concordance in the direction of effects across racial/ethnic groups, a high correlation of effect sizes between high-density lipoprotein and triglycerides, a modest overlap of associations with epigenome-wide association studies of other cardio-metabolic traits, and a largely non-overlap with lipid loci identified to date through genome-wide association studies. Thirty CpGs reached significance in at least 2 racial/ethnic groups including 7 that showed association with the expression of an annotated gene. CpGs annotated to CPT1A showed evidence of being influenced by triglycerides levels. DNA methylation levels of circulating leukocytes show robust and consistent association with blood lipid levels across multiple racial/ethnic groups. Abnormal blood lipid levels are important risk factors for cardiovascular and other various diseases. Here the authors conduct a large-scale multi-ethnic epigenome-wide association study combined with epigenetic (cis-QTL and eQTM) data, and identify CpG-lipid traits associations that are specific to or common across racial/ethnic groups.
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- 2021
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94. Atopy is predictive of a decreased need for hospitalization for coronavirus disease 2019
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Keswani, Anjeni, Dhana, Klodian, Rosenthal, Jamie A., Moore, Donyea, and Mahdavinia, Mahboobeh
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- 2020
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95. The Stability of Vitamins D and K of the Human Brain During Freezer Storage: The Memory and Aging Project (MAP)
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Fu, Xueyan, Shea, M. Kyla, Dolnikowski, Gregory, Dawson-Hughes, Bess, Morris, Martha, Holland, Thomas, Dhana, Klodian, and Booth, Sarah
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- 2020
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96. Free-Living Standing Activity as Assessed by Seismic Accelerometers and Cognitive Function in Community-Dwelling Older Adults: The MIND Trial
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Halloway, Shannon, primary, Dhana, Klodian, additional, Desai, Pankaja, additional, Agarwal, Puja, additional, Holland, Thomas, additional, Aggarwal, Neelum T, additional, Evers, Jordi, additional, Sacks, Frank M, additional, Carey, Vincent J, additional, and Barnes, Lisa L, additional
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- 2021
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97. Gastrointestinal Symptoms Predict the Outcomes From COVID-19 Infection
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Bishehsari, Faraz, primary, Adnan, Darbaz, additional, Deshmukh, Ameya, additional, Khan, Shahab R., additional, Rempert, Trevor, additional, Dhana, Klodian, additional, and Mahdavinia, Mahboobeh, additional
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- 2021
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98. Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline
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Liu, Xiaoran, primary, Morris, Martha Clare, additional, Dhana, Klodian, additional, Ventrelle, Jennifer, additional, Johnson, Kathleen, additional, Bishop, Louise, additional, Hollings, Chiquia S., additional, Boulin, Adrianna, additional, Laranjo, Nancy, additional, Stubbs, Benjamin J., additional, Reilly, Xavier, additional, Carey, Vincent J., additional, Wang, Yamin, additional, Furtado, Jeremy D., additional, Marcovina, Santica M., additional, Tangney, Christy, additional, Aggarwal, Neelum T., additional, Arfanakis, Konstantinos, additional, Sacks, Frank M., additional, and Barnes, Lisa L., additional
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- 2021
- Full Text
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99. Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
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Rodriguez-Martinez, Andrea, Zhou, Bin, Sophiea, Marisa K, Bentham, James, Paciorek, Christopher J, Iurilli, Maria LC, Carrillo-Larco, Rodrigo M, Bennett, James E, Di Cesare, Mariachiara, Taddei, Cristina, Bixby, Honor, Stevens, Gretchen A, Riley, Leanne M, Cowan, Melanie J, Savin, Stefan, Danaei, Goodarz, Chirita-Emandi, Adela, Kengne, Andre P, Khang, Young-Ho, Laxmaiah, Avula, Malekzadeh, Reza, Miranda, J Jaime, Moon, Jin Soo, Popovic, Stevo R, Sorensen, Thorkild IA, Soric, Maroje, Starc, Gregor, Zainuddin, Ahmad A, Gregg, Edward W, Bhutta, Zulfiqar A, Black, Robert, Ezzati, Majid, Abarca-Gomez, Leandra, Abdeen, Ziad A, Abdrakhmanova, Shynar, Ghaffar, Suhaila Abdul, Rahim, Hanan F Abdul, Abu-Rmeileh, Niveen M, Garba, Jamila Abubakar, Acosta-Cazares, Benjamin, Adams, Robert J, Aekplakorn, Wichai, Afsana, Kaosar, Afzal, Shoaib, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmed, Soheir H, Ahrens, Wolfgang, Aitmurzaeva, Gulmira, Ajlouni, Kamel, Al-Hazzaa, Hazzaa M, Al-Othman, Amani Rashed, Al-Raddadi, Rajaa, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Allin, Kristine, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N, Amiri, Parisa, Amougou, Norbert, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A, Angquist, Lars, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araujo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assah, Felix K, Assuncao, Maria Cecilia F, Aung, May Soe, Auvinen, Juha, Avdicova, Maria, Azevedo, Ana, Azimi-Nezhad, Mohsen, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V, Jorgensen, Maja Baeksgaard, Baharudin, Azli, Bahijri, Suhad, Baker, Jennifer L, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, Jose R, Baran, Joanna, Barbagallo, 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Juresa V., Kaaks R., Kaducu F.O., Kafatos A., Kajantie E.O., Kalmatayeva Z., Kalter-Leibovici O., Kameli Y., Kanala K.R., Kannan S., Kapantais E., Karki K.B., Katibeh M., Katz J., Katzmarzyk P.T., Kauhanen J., Kaur P., Kavousi M., Kazakbaeva G.M., Keil U., Keinan Boker L., Keinanen-Kiukaanniemi S., Kelishadi R., Kelleher C., Kemper H.C., Keramati M., Kerimkulova A., Kersting M., Key T., Khader Y.S., Khalili D., Khaw K.-T., Kheiri B., Kheradmand M., Khosravi A., Khouw I.M., Kiechl-Kohlendorfer U., Kiechl S., Killewo J., Kim D.W., Kim H.C., Kim J., Kindblom J.M., Klakk H., Klimek M., Klimont J., Klumbiene J., Knoflach M., Koirala B., Kolle E., Kolsteren P., Konig J., Korpelainen R., Korrovits P., Korzycka M., Kos J., Koskinen S., Kouda K., Kovacs V.A., Kowlessur S., Koziel S., Kratzer W., Kriemler S., Kristensen P.L., Krokstad S., Kromhout D., Krtalic B., Kruger H.S., Kubinova R., Kuciene R., Kujala U.M., Kujundzic E., Kulaga Z., Kumar R.K., Kunesova M., Kurjata P., Kusuma Y.S., Kuulasmaa K., Kyobutungi C., La Q.N., Laamiri F.Z., Laatikainen T., Lachat C., Laid Y., Lam T.H., Lambrinou C.-P., Landais E., Lanska V., Lappas G., Larijani B., Latt T.S., Lauria L., Lazo-Porras M., Le Nguyen Bao K., Le Port A., Le T.D., Lee J., Lee P.H., Lehmann N., Lehtimaki T., Lemogoum D., Levitt N.S., Li Y., Liivak M., Lilly C.L., Lim W.-Y., Lima-Costa M.F., Lin H.-H., Lin X., Lin Y.-T., Lind L., Linneberg A., Lissner L., Litwin M., Liu J., Liu L., Lo W.-C., Loit H.-M., Long K.Q., Lopes L., Lopes O., Lopez-Garcia E., Lopez T., Lotufo P.A., Lozano J.E., Lukrafka J.L., Luksiene D., Lundqvist A., Lundqvist R., Lunet N., Lunogelo C., Lustigova M., Luszczki E., Ma G., Ma J., Ma X., Machado-Coelho G.L., Machado-Rodrigues A.M., Machi S., Macieira L.M., Madar A.A., Maggi S., Magliano D.J., Magnacca S., Magriplis E., Mahasampath G., Maire B., Majer M., Makdisse M., Maki P., Malekzadeh F., Malhotra R., Mallikharjuna Rao K., Malyutina S.K., Maniego L.V., Manios Y., Mann J.I., Mansour-Ghanaei F., Manzato E., Margozzini P., Markaki A., Markey O., Markidou Ioannidou E., Marques-Vidal P., Marques L.P., Marrugat J., Martin-Prevel Y., Martin R., Martorell R., Martos E., Marventano S., Mascarenhas L.P., Masoodi S.R., Mathiesen E.B., Mathur P., Matijasevich A., Matsha T.E., Mavrogianni C., Mazur A., Mbanya J.C.N., McFarlane S.R., McGarvey S.T., McKee M., McLachlan S., McLean R.M., McLean S.B., McNulty B.A., Mediene-Benchekor S., Medzioniene J., Mehdipour P., Mehlig K., Mehrparvar A.H., Meirhaeghe A., Meisfjord J., Meisinger C., Menezes A.M.B., Menon G.R., Mensink G.B., Menzano M.T., Mereke A., Meshram I.I., Metspalu A., Mi J., Michaelsen K.F., Michels N., Mikkel K., Milkowska K., Miller J.C., Minderico C.S., Mini G.K., Miquel J.F., Mirjalili M.R., Mirkopoulou D., Mirrakhimov E., Misigoj-Durakovic M., Mistretta A., Mocanu V., Modesti P.A., Moghaddam S.S., Mohajer B., Mohamed M.K., Mohamed S.F., Mohammad K., Mohammadi Z., Mohammadifard N., Mohammadpourhodki R., Mohan V., Mohanna S., Mohd Yusoff M.F., Mohebbi I., Mohebi F., Moitry M., Molbo D., Mollehave L.T., Moller N.C., Molnar D., Momenan A., Mondo C.K., Monroy-Valle M., Monterrubio-Flores E., Monyeki K.D.K., Moosazadeh M., Moreira L.B., Morejon A., Moreno L.A., Morgan K., Morin S.N., Mortensen E.L., Moschonis G., Mossakowska M., Mostafa A., Mota-Pinto A., Mota J., Motlagh M.E., Motta J., Moura-dos-Santos M.A., Mridha M.K., Msyamboza K.P., Mu T.T., Muc M., Mugosa B., Muiesan M.L., Mukhtorova P., Muller-Nurasyid M., Murphy N., Mursu J., Murtagh E.M., Musa K.I., Music Milanovic S., Musil V., Mustafa N., Nabipour I., Naderimagham S., Nagel G., Naidu B.M., Najafi F., Nakamura H., Namesna J., Nang E.E.K., Nangia V.B., Nankap M., Narake S., Nardone P., Nauck M., Neal W.A., Nejatizadeh A., Nelis K., Nelis L., Nenko I., Neovius M., Nervi F., Nguyen C.T., Nguyen D., Nguyen Q.N., Nieto-Martinez R.E., Nikitin Y.P., Ning G., Ninomiya T., Nishtar S., Noale M., Noboa O.A., Nogueira H., Norat T., Nordendahl M., Nordestgaard B.G., Noto D., Nowak-Szczepanska N., Nsour M.A., Nuhoglu I., Nurk E., O'Neill T.W., O'Reilly D., Obreja G., Ochimana C., Ochoa-Aviles A.M., Oda E., Oh K., Ohara K., Ohlsson C., Ohtsuka R., Olafsson O., Olinto M.T.A., Oliveira I.O., Omar M.A., Onat A., Ong S.K., Ono L.M., Ordunez P., Ornelas R., Ortiz A.P., Ortiz P.J., Osler M., Osmond C., Ostojic S.M., Ostovar A., Otero J.A., Overvad K., Owusu-Dabo E., Paccaud F.M., Padez C., Pagkalos I., Pahomova E., Paiva K.M.D., Pajak A., Palli D., Palloni A., Palmieri L., Pan W.-H., Panda-Jonas S., Pandey A., Panza F., Papandreou D., Park S.-W., Park S., Parnell W.R., Parsaeian M., Pascanu I.M., Pasquet P., Patel N.D., Pednekar M.S., Peer N., Peixoto S.V., Peltonen M., Pereira A.C., Peres M.A., Perez-Farinos N., Perez C.M., Peterkova V., Peters A., Petersmann A., Petkeviciene J., Petrauskiene A., Pettenuzzo E., Peykari N., Pham S.T., Pichardo R.N., Pierannunzio D., Pigeot I., Pikhart H., Pilav A., Pilotto L., Pistelli F., Pitakaka F., Piwonska A., Pizarro A.N., Plans-Rubio P., Poh B.K., Pohlabeln H., Pop R.M., Porta M., Posch G., Poudyal A., Poulimeneas D., Pouraram H., Pourfarzi F., Pourshams A., Poustchi H., Pradeepa R., Price A.J., Price J.F., Providencia R., Puder J.J., Pudule I., Puhakka S.E., Puiu M., Punab M., Qasrawi R.F., Qorbani M., Quoc Bao T., Radic I., Radisauskas R., Rahimikazerooni S., Rahman M., Raitakari O., Raj M., Rakhimova E., Rakhmatulloev S., Rakovac I., Ramachandra Rao S., Ramachandran A., Ramke J., Ramos E., Ramos R., Rampal L., Rampal S., Rarra V., Rascon-Pacheco R.A., Rasmussen M., Rech C.R., Redon J., Reganit P.F.M., Regecova V., Revilla L., Rezaianzadeh A., Ribas-Barba L., Ribeiro R., Riboli E., Richter A., Rigo F., Rinaldo N., Rinke de Wit T.F., Rito A., Ritti-Dias R.M., Rivera J.A., Robitaille C., Roccaldo R., Rodrigues D., Rodriguez-Artalejo F., Rodriguez-Perez M.D.C., Rodriguez-Villamizar L.A., Roggenbuck U., Rojas-Martinez R., Rojroongwasinkul N., Romaguera D., Romeo E.L., Rosario R.V., Rosengren A., Rouse I., Roy J.G., Rubinstein A., Ruhli F.J., Ruidavets J.-B., Ruiz-Betancourt B.S., Ruiz Moreno E., Rusakova I.A., Russell Jonsson K., Russo P., Rust P., Rutkowski M., Sabanayagam C., Sacchini E., Sachdev H.S., Sadjadi A., Safarpour A.R., Safi S., Safiri S., Saidi O., Saki N., Salanave B., Salazar Martinez E., Salmeron D., Salomaa V., Salonen J.T., Salvetti M., Samoutian M., Sanchez-Abanto J., Sandjaja, Sans S., Santa Marina L., Santos D.A., Santos I.S., Santos L.C., Santos M.P., Santos O., Santos R., Santos Sanz S., Saramies J.L., Sardinha L.B., Sarrafzadegan N., Sathish T., Saum K.-U., Savva S., Savy M., Sawada N., Sbaraini M., Scazufca M., Schaan B.D., Schaffrath Rosario A., Schargrodsky H., Schienkiewitz A., Schindler K., Schipf S., Schmidt C.O., Schmidt I.M., Schnohr P., Schottker B., Schramm S., Schroder H., Schultsz C., Schutte A.E., Sebert S., Sein A.A., Selamat R., Sember V., Sen A., Senbanjo I.O., Sepanlou S.G., Sequera V., Serra-Majem L., Servais J., Sevcikova L., Shalnova S.A., Shamah-Levy T., Shamshirgaran M., Shanthirani C.S., Sharafkhah M., Sharma S.K., Shaw J.E., Shayanrad A., Shayesteh A.A., Shengelia L., Shi Z., Shibuya K., Shimizu-Furusawa H., Shin D.W., Shin Y., Shirani M., Shiri R., Shrestha N., Si-Ramlee K., Siani A., Siantar R., Sibai A.M., Silva A.M., Silva D.A.S., Simon M., Simons J., Simons L.A., Sjoberg A., Sjostrom M., Skodje G., Slowikowska-Hilczer J., Slusarczyk P., Smeeth L., So H.-K., Soares F.C., Sobek G., Sobngwi E., Sodemann M., Soderberg S., Soekatri M.Y., Soemantri A., Sofat R., Solfrizzi V., Somi M.H., Sonestedt E., Song Y., Sorgjerd E.P., Sossa Jerome C., Soto-Rojas V.E., Soumare A., Sovic S., Sparboe-Nilsen B., Sparrenberger K., Spinelli A., Spiroski I., Staessen J.A., Stamm H., Stathopoulou M.G., Staub K., Stavreski B., Steene-Johannessen J., Stehle P., Stein A.D., Stergiou G.S., Stessman J., Stevanovic R., Stieber J., Stockl D., Stocks T., Stokwiszewski J., Stoyanova E., Stratton G., Stronks K., Strufaldi M.W., Sturua L., Suarez-Medina R., Suka M., Sun C.-A., Sundstrom J., Sung Y.-T., Sunyer J., Suriyawongpaisal P., Swinburn B.A., Sy R.G., Syddall H.E., Sylva R.C., Szklo M., Szponar L., Tai E.S., Tammesoo M.-L., Tamosiunas A., Tan E.J., Tang X., Tanser F., Tao Y., Tarawneh M.R., Tarp J., Tarqui-Mamani C.B., Taxova Braunerova R., Taylor A., Taylor J., Tchibindat F., Tebar W.R., Tell G.S., Tello T., Thankappan K.R., Theobald H., Theodoridis X., Thijs L., Thomas N., Thuesen B.H., Ticha L., Timmermans E.J., Tjonneland A., Tolonen H.K., Tolstrup J.S., Topbas M., Topor-Madry R., Torheim L.E., Tormo M.J., Tornaritis M.J., Torrent M., Torres-Collado L., Toselli S., Traissac P., Tran T.T.-H., Trichopoulos D., Trichopoulou A., Trinh O.T., Trivedi A., Tshepo L., Tsigga M., Tsugane S., Tuliakova A.M., Tulloch-Reid M.K., Tullu F., Tuomainen T.-P., Tuomilehto J., Turley M.L., Tynelius P., Tzotzas T., Tzourio C., Ueda P., Ugel E., Ukoli F.A., Ulmer H., Unal B., Usupova Z., Uusitalo H.M., Uysal N., Vaitkeviciute J., Valdivia G., Vale S., Valvi D., van Dam R.M., Van der Heyden J., van der Schouw Y.T., Van Herck K., Van Minh H., van Valkengoed I.G., Vanderschueren D., Vanuzzo D., Varbo A., Varela-Moreiras G., Varona-Perez P., Vasan S.K., Vega T., Veidebaum T., Velasquez-Melendez G., Velika B., Veronesi G., Verschuren W.M., Victora C.G., Viegi G., Viet L., Villalpando S., Vineis P., Vioque J., Virtanen J.K., Visser M., Visvikis-Siest S., Viswanathan B., Vladulescu M., Vlasoff T., Vocanec D., Volzke H., Voutilainen A., Voutilainen S., Vrijheid M., Vrijkotte T.G., Wade A.N., Wagner A., Waldhor T., Walton J., Wambiya E.O., Wan Bebakar W.M., Wan Mohamud W.N., Wanderley Junior R.D.S., Wang M.-D., Wang N., Wang Q., Wang X., Wang Y.X., Wang Y.-W., Wannamethee S.G., Wareham N., Weber A., Wedderkopp N., Weerasekera D., Weghuber D., Wei W., Weres A., Werner B., Whincup P.H., Widhalm K., Widyahening I.S., Wiecek A., Wilks R.J., Willeit J., Willeit P., Williams J., Wilsgaard T., Wojtyniak B., Wong-McClure R.A., Wong A., Wong J.E., Wong T.Y., Woo J., Woodward M., Wu F.C., Wu J., Wu L.J., Wu S., Xu H., Xu L., Yaacob N.A., Yamborisut U., Yan W., Yang L., Yang X., Yang Y., Yardim N., Yaseri M., Yasuharu T., Ye X., Yiallouros P.K., Yoosefi M., Yoshihara A., You Q.S., You S.-L., Younger-Coleman N.O., Yusof S.M., Yusoff A.F., Zaccagni L., Zafiropulos V., Zakavi S.R., Zamani F., Zambon S., Zampelas A., Zamrazilova H., Zapata M.E., Zargar A.H., Zaw K.K., Zdrojewski T., Zeljkovic Vrkic T., Zeng Y., Zhang L., Zhang Z.-Y., Zhao D., Zhao M.-H., Zhao W., Zhen S., Zheng W., Zheng Y., Zholdin B., Zhou M., Zhu D., Zocalo Y., Zuniga Cisneros J., Zuziak M., and Ezzati M.
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Male ,body-mass index ,ADULTHOOD ,Adolescents ,pituuskasvu ,Pediatrics ,Body Mass Index ,0302 clinical medicine ,Child Development ,nuoret ,Public health surveillance ,Medicine ,Health Status Indicators ,10. No inequality ,Child ,11 Medical and Health Sciences ,Body mass index ,ComputingMilieux_MISCELLANEOUS ,education.field_of_study ,VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801 ,General Medicine ,Body mass indexes ,kansainvälinen vertailu ,3. Good health ,Geography ,Health ,030220 oncology & carcinogenesis ,Child, Preschool ,Medical and Health sciences ,purl.org/becyt/ford/3 [https] ,medicine.medical_specialty ,School-aged adolescents ,Socio-culturale ,lapset (ikäryhmät) ,Nursing ,territories ,ravinto ,purl.org/becyt/ford/3.3 [https] ,03 medical and health sciences ,School Children ,SDG 3 - Good Health and Well-being ,SYSTEMATIC ANALYSIS ,Humans ,school-aged children and adolescents ,Montenegro ,education ,Science & Technology ,Omvårdnad ,Health sciences, Medical and Health sciences ,Ciências médicas e da saúde ,Bayes Theorem ,Anthropometry ,Adolescent Development ,medicine.disease ,TRENDS ,Height and Body-mass Index ,Faculdade de Ciências Sociais ,UNDERNUTRITION ,Height index trajectories ,Height, body mass index, children , epidemiology ,risk factors, growth ,Stature ,Demography ,Settore MED/09 - Medicina Interna ,Internationality ,[SDV]Life Sciences [q-bio] ,030204 cardiovascular system & hematology ,Body-mass index trajectories ,Epidemiology ,Medicine and Health Sciences ,risk factors ,countries ,EPIDEMIOLOGY ,height ,children ,adolescents ,BMI ,030212 general & internal medicine ,painoindeksi ,Child development ,2. Zero hunger ,Medicine(all) ,School age child ,obestity children cardiovascular ,Population Health ,1. No poverty ,Pediatrik ,Public Health, Global Health, Social Medicine and Epidemiology ,3142 Public health care science, environmental and occupational health ,Pooled analysis ,NUTRITION ,Female ,medicine.symptom ,pooled analysis ,Life Sciences & Biomedicine ,terveys ,height, BMI, nutrition, health, children, adolescents ,Adolescent ,growth ,Population ,body-mass ,Population based ,Body-mass index ,Young Adult ,Medicine, General & Internal ,Meta-Analysis as Topic ,General & Internal Medicine ,parasitic diseases ,Weight gain ,School-aged childrens ,Age trajectories ,business.industry ,Height ,Weight ,Body Height ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Malnutrition ,ONSET ,Ciências da Saúde, Ciências médicas e da saúde ,School-aged children ,VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801 ,business ,terveysriskit ,Estilos de Vida e Impacto na Saúde - Abstract
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents., METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence., FINDINGS: We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls., INTERPRETATION: The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks., Wellcome Trust, AstraZeneca Young Health Programme, EU., peer-reviewed
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- 2020
100. Repositioning of the global epicentre of non-optimal cholesterol
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Taddei, Cristina, Zhou, Bin, Bixby, Honor, Carrillo-Larco, Rodrigo M, Danaei, Goodarz, Jackson, Rod T, Farzadfar, Farshad, Sophiea, Marisa K, Di Cesare, Mariachiara, Iurilli, Maria Laura Caminia, Martinez, Andrea Rodriguez, Asghari, Golaleh, Dhana, Klodian, Gulayin, Pablo, Kakarmath, Sujay, Santero, Marilina, Voortman, Trudy, Riley, Leanne M, Cowan, Melanie J, Savin, Stefan, Bennett, James E, Stevens, Gretchen A, Paciorek, Christopher J, Aekplakorn, Wichai, Cifkova, Renata, Giampaoli, Simona, Kengne, Andre Pascal, Khang, Young-Ho, Kuulasmaa, Kari, Laxmaiah, Avula, Margozzini, Paula, Mathur, Prashant, Nordestgaard, Børge G, Zhao, Dong, Aadahl, Mette, Abarca-Gómez, Leandra, Rahim, Hanan Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert J, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahluwalia, Tarunveer S, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmed, Soheir H, Ahrens, Wolfgang, Ajlouni, Kamel, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Aly, Eman, Amarapurkar, Deepak N, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assunção, Maria Cecília F, Auvinen, Juha, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Azmin, Mehrdad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Bata, Iqbal, Batieha, Anwar M, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benet, Mikhail, Benn, Marianne, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhargava, Santosh K, Tan, Eng Joo, Taddei, Cristina, Zhou, Bin, Bixby, Honor, Carrillo-Larco, Rodrigo M, Danaei, Goodarz, Jackson, Rod T, Farzadfar, Farshad, Sophiea, Marisa K, Di Cesare, Mariachiara, Iurilli, Maria Laura Caminia, Martinez, Andrea Rodriguez, Asghari, Golaleh, Dhana, Klodian, Gulayin, Pablo, Kakarmath, Sujay, Santero, Marilina, Voortman, Trudy, Riley, Leanne M, Cowan, Melanie J, Savin, Stefan, Bennett, James E, Stevens, Gretchen A, Paciorek, Christopher J, Aekplakorn, Wichai, Cifkova, Renata, Giampaoli, Simona, Kengne, Andre Pascal, Khang, Young-Ho, Kuulasmaa, Kari, Laxmaiah, Avula, Margozzini, Paula, Mathur, Prashant, Nordestgaard, Børge G, Zhao, Dong, Aadahl, Mette, Abarca-Gómez, Leandra, Rahim, Hanan Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert J, Agdeppa, Imelda A, Aghazadeh-Attari, Javad, Aguilar-Salinas, Carlos A, Agyemang, Charles, Ahluwalia, Tarunveer S, Ahmad, Noor Ani, Ahmadi, Ali, Ahmadi, Naser, Ahmed, Soheir H, Ahrens, Wolfgang, Ajlouni, Kamel, Alarouj, Monira, AlBuhairan, Fadia, AlDhukair, Shahla, Ali, Mohamed M, Alkandari, Abdullah, Alkerwi, Ala'a, Aly, Eman, Amarapurkar, Deepak N, Amouyel, Philippe, Andersen, Lars Bo, Anderssen, Sigmund A, Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E, Arlappa, Nimmathota, Aryal, Krishna K, Aspelund, Thor, Assunção, Maria Cecília F, Auvinen, Juha, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Azmin, Mehrdad, Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, José R, Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Bata, Iqbal, Batieha, Anwar M, Batyrbek, Assembekov, Baur, Louise A, Beaglehole, Robert, Belavendra, Antonisamy, Ben Romdhane, Habiba, Benet, Mikhail, Benn, Marianne, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhargava, Santosh K, and Tan, Eng Joo
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- 2020
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