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51. Measurement of Atmospheric Neutrino Mixing with Improved IceCube DeepCore Calibration and Data Processing

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benning, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chau, N., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., Delgado, D., Dembinski, H., Deng, S., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Mentawi, S. El, Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Gries, O., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hori, S., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Ishihara, A., Jacquart, M., Janik, O., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krishnamoorthi, J., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Latseva, S., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Micallef, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, O'Dell, V., Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Rifaie, A., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlickmann, L., Schlüter, B., Schlüter, F., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seikh, M., Seunarine, S., Shah, R., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, A., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Young, R., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract: We describe a new data sample of IceCube DeepCore and report on the latest measurement of atmospheric neutrino oscillations obtained with data recorded between 2011-2019. The sample includes significant improvements in data calibration, detector simulation, and data processing, and the analysis benefits from a detailed treatment of systematic uncertainties, with significantly higher level of detail since our last study. By measuring the relative fluxes of neutrino flavors as a function of their reconstructed energies and arrival directions we constrain the atmospheric neutrino mixing parameters to be $\sin^2\theta_{23} = 0.51\pm 0.05$ and $\Delta m^2_{32} = 2.41\pm0.07\times 10^{-3}\mathrm{eV}^2$, assuming a normal mass ordering. The resulting 40\% reduction in the error of both parameters with respect to our previous result makes this the most precise measurement of oscillation parameters using atmospheric neutrinos. Our results are also compatible and complementary to those obtained using neutrino beams from accelerators, which are obtained at lower neutrino energies and are subject to different sources of uncertainties.
Published: 2023
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52. IceCat-1: the IceCube Event Catalog of Alert Tracks

Author: Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chau, N., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., Delgado, D., Dembinski, H., Deng, S., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Ishihara, A., Jacquart, M., Janik, O., Jansson, M., Japaridze, G. S., Jayakumar, K., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Madsen, J., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Micallef, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, O'Dell, V., Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schlüter, F., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Shah, R., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thiesmeyer, M., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, A., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present a catalog of likely astrophysical neutrino track-like events from the IceCube Neutrino Observatory. IceCube began reporting likely astrophysical neutrinos in 2016 and this system was updated in 2019. The catalog presented here includes events that were reported in real-time since 2019, as well as events identified in archival data samples starting from 2011. We report 275 neutrino events from two selection channels as the first entries in the catalog, the IceCube Event Catalog of Alert Tracks, which will see ongoing extensions with additional alerts. The gold and bronze alert channels respectively provide neutrino candidates with 50\% and 30\% probability of being astrophysical, on average assuming an astrophysical neutrino power law energy spectral index of 2.19. For each neutrino alert, we provide the reconstructed energy, direction, false alarm rate, probability of being astrophysical in origin, and likelihood contours describing the spatial uncertainty in the alert's reconstructed location. We also investigate a directional correlation of these neutrino events with gamma-ray and X-ray catalogs including 4FGL, 3HWC, TeVCat and Swift-BAT., Comment: Published in ApJS. Figure 4 and 6 corrected. Online version of the catalog is available on dataverse at https://doi.org/10.7910/DVN/SCRUCD
Published: 2023
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53. A Search for IceCube sub-TeV Neutrinos Correlated with Gravitational-Wave Events Detected By LIGO/Virgo

Author: Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chau, N., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Ishihara, A., Jacquart, M., Jansson, M., Japaridze, G. S., Jayakumar, K., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, O'Dell, V., Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schlüter, F., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The LIGO/Virgo collaboration published the catalogs GWTC-1, GWTC-2.1 and GWTC-3 containing candidate gravitational-wave (GW) events detected during its runs O1, O2 and O3. These GW events can be possible sites of neutrino emission. In this paper, we present a search for neutrino counterparts of 90 GW candidates using IceCube DeepCore, the low-energy infill array of the IceCube Neutrino Observatory. The search is conducted using an unbinned maximum likelihood method, within a time window of 1000 s and uses the spatial and timing information from the GW events. The neutrinos used for the search have energies ranging from a few GeV to several tens of TeV. We do not find any significant emission of neutrinos, and place upper limits on the flux and the isotropic-equivalent energy emitted in low-energy neutrinos. We also conduct a binomial test to search for source populations potentially contributing to neutrino emission. We report a non-detection of a significant neutrino-source population with this test.
Published: 2023
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54. Search for neutrino lines from dark matter annihilation and decay with IceCube

Author: The IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deng, S., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Aisati, C. El, Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Gustafsson, M., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hambye, T., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Hauser, S., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jacquart, M., Jansson, M., Japaridze, G. S., Jayakumar, K., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mari{ş}, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: Dark Matter particles in the Galactic Center and halo can annihilate or decay into a pair of neutrinos producing a monochromatic flux of neutrinos. The spectral feature of this signal is unique and it is not expected from any astrophysical production mechanism. Its observation would constitute a dark matter smoking gun signal. We performed the first dedicated search with a neutrino telescope for such signal, by looking at both the angular and energy information of the neutrino events. To this end, a total of five years of IceCube's DeepCore data has been used to test dark matter masses ranging from 10~GeV to 40~TeV. No significant neutrino excess was found and upper limits on the annihilation cross section, as well as lower limits on the dark matter lifetime, were set. The limits reached are of the order of $10^{-24}$~cm$^3/s$ for an annihilation and up to $10^{27}$ seconds for decaying Dark Matter. Using the same data sample we also derive limits for dark matter annihilation or decay into a pair of Standard Model charged particles.
Published: 2023

55. Constraining the Astrophysical p Process: Cross Section Measurement of the 84Kr(p,g)85Rb Reaction in Inverse Kinematics

Author: Palmisano-Kyle, Alicia, Spyrou, Artemis, DeYoung, Paul, Gastis, Panagiotis, Olivas-Gomez, Orlando, Harris, Caley, Liddick, Sean, Lyons, Stephanie, Pereira, Jorge, Richard, Andrea, Simon, Anna, Smith, Mallory, Tsantiri, Artemis, and Zegers, Remco
Subjects: Nuclear Experiment
Abstract: One of the biggest questions in nuclear astrophysics is understanding where the elements come from and how they are made. This work focuses on the p process, a nucleosynthesis process that consists of a series of photodisintegration reactions responsible for producing stable isotopes on the proton-rich side of stability. These nuclei, known as the p nuclei, cannot be made through the well-known neutron-capture processes. Currently p-process models rely heavily on theory to provide the relevant reaction rates to predict the final p-nuclei abundances and more experimental data is needed. The present work reports on an experiment performed with the SuN detector at the National Superconducting Cyclotron Laboratory, NSCL, at Michigan State University using the ReA facility to measure the $^{84}$Kr(p,$\gamma$)$^{85}$Rb reaction cross section in inverse kinematics. The reverse $^{85}$Rb($\gamma$,p)$^{84}$Kr reaction is a branching point in the p-process reaction network that was highlighted as an important reaction in sensitivity studies in the production of the $^{78}$Kr p nucleus. A new hydrogen gas target was designed and fabricated and a new analysis technique for background subtraction and efficiency calculations of the detector were developed. The experimental cross section is compared to standard statistical model calculations using the NON-SMOKER and TALYS codes.
Published: 2023
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56. Observation of Seasonal Variations of the Flux of High-Energy Atmospheric Neutrinos with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deng, S., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Hauser, S., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jacquart, M., Jansson, M., Japaridze, G. S., Jayakumar, K., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Atmospheric muon neutrinos are produced by meson decays in cosmic-ray-induced air showers. The flux depends on meteorological quantities such as the air temperature, which affects the density of air. Competition between decay and re-interaction of those mesons in the first particle production generations gives rise to a higher neutrino flux when the air density in the stratosphere is lower, corresponding to a higher temperature. A measurement of a temperature dependence of the atmospheric $\nu_{\mu}$ flux provides a novel method for constraining hadro\-nic interaction models of air showers. It is particularly sensitive to the production of kaons. Studying this temperature dependence for the first time requires a large sample of high-energy neutrinos as well as a detailed understanding of atmospheric properties. We report the significant ($> 10 \sigma$) observation of a correlation between the rate of more than 260,000 neutrinos, detected by IceCube between 2012 and 2018, and atmospheric temperatures of the stratosphere, measured by the Atmospheric Infrared Sounder (AIRS) instrument aboard NASA's AQUA satellite. For the observed 10$\%$ seasonal change of effective atmospheric temperature we measure a 3.5(3)$\%$ change in the muon neutrino flux. This observed correlation deviates by about 2-3 standard deviations from the expected correlation of 4.3$\%$ as obtained from theoretical predictions under the assumption of various hadronic interaction models, Comment: Preprint submitted to EPJC
Published: 2023
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57. Constraining High-Energy Neutrino Emission from Supernovae with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Butterfield, D., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chattopadhyay, S., Chau, N., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Ishihara, A., Jacquart, M., Jansson, M., Japaridze, G. S., Jayakumar, K., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, O'Dell, V., Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schlüter, F., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Core-collapse supernovae are a promising potential high-energy neutrino source class. We test for correlation between seven years of IceCube neutrino data and a catalog containing more than 1000 core-collapse supernovae of types IIn and IIP and a sample of stripped-envelope supernovae. We search both for neutrino emission from individual supernovae, and for combined emission from the whole supernova sample through a stacking analysis. No significant spatial or temporal correlation of neutrinos with the cataloged supernovae was found. The overall deviation of all tested scenarios from the background expectation yields a p-value of 93% which is fully compatible with background. The derived upper limits on the total energy emitted in neutrinos are $1.7\times 10^{48}$ erg for stripped-envelope supernovae, $2.8\times 10^{48}$ erg for type IIP, and $1.3\times 10^{49}$ erg for type IIn SNe, the latter disfavouring models with optimistic assumptions for neutrino production in interacting supernovae. We conclude that strippe-envelope supernovae and supernovae of type IIn do not contribute more than $14.6\%$ and $33.9\%$ respectively to the diffuse neutrino flux in the energy range of about $10^3-10^5$ GeV, assuming that the neutrino energy spectrum follows a power-law with an index of $-2.5$. Under the same assumption, we can only constrain the contribution of type IIP SNe to no more than $59.9\%$. Thus core-collapse supernovae of types IIn and stripped-envelope supernovae can both be ruled out as the dominant source of the diffuse neutrino flux under the given assumptions., Comment: Submitted to ApJ Letters
Published: 2023
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58. Obstructive sleep apnea and psychomotor vigilance task performance

Author: Batool-Anwar S, Kales SN, Patel SR, Varvarigou V, DeYoung PN, and Malhotra A
Subjects: Psychiatry, RC435-571, Neurophysiology and neuropsychology, QP351-495
Abstract: Salma Batool-Anwar,1 Stefanos N Kales,3,4 Sanjay R Patel,1 Vasileia Varvarigou,3 Pamela N DeYoung,2 Atul Malhotra21Department of Medicine, Sleep Disorders Program, Brigham and Women's Hospital, Boston, MA, USA; 2Pulmonary Critical Care Division, University of California San Diego, La Jolla, CA, USA; 3Department of Environmental and Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, 4Department of Occupational Medicine, The Cambridge Health Alliance, Cambridge, MA, USABackground: Obstructive sleep apnea (OSA) is a highly prevalent disorder with considerable morbidity and mortality. Vigilance and attentiveness are often impaired in OSA patients. In occupational medicine settings, subjective reports of sleepiness are notoriously inaccurate, making the identification of objective measures of vigilance potentially important for risk assessments of fitness for duty. In order to evaluate the effects of OSA on attentiveness and vigilance, we conducted a cross-sectional study to examine the association between OSA and psychomotor vigilance task (PVT) performance.Methods: Patients attending sleep clinics for evaluation of possible sleep apnea were recruited. The subjects underwent either a standard overnight laboratory polysomnography or home sleep study. Subjective daytime sleepiness was assessed by Epworth sleepiness scale, and vigilance was tested using a portable device. The participants were asked to respond to the PVT signals using their dominant hand. Each PVT administration lasted 10 minutes, with stimuli signals appearing randomly at variable intervals of 2–10 seconds.Results: Mean age of the participants was 46±15 years, and mean body mass index was 34.3±9.8 kg/m2. Participants with higher Epworth scores had worse PVT performance (P
Published: 2014

59. DNA methylation networks underlying mammalian traits.

Author: Haghani, Amin, Li, Caesar, Robeck, Todd, Zhang, Joshua, Lu, Ake, Ablaeva, Julia, Acosta-Rodríguez, Victoria, Adams, Danielle, Alagaili, Abdulaziz, Almunia, Javier, Aloysius, Ajoy, Amor, Nabil, Ardehali, Reza, Arneson, Adriana, Baker, C, Banks, Gareth, Belov, Katherine, Bennett, Nigel, Black, Peter, Blumstein, Daniel, Bors, Eleanor, Breeze, Charles, Brooke, Robert, Brown, Janine, Carter, Gerald, Caulton, Alex, Cavin, Julie, Chakrabarti, Lisa, Chatzistamou, Ioulia, Chavez, Andreas, Chen, Hao, Cheng, Kaiyang, Chiavellini, Priscila, Choi, Oi-Wa, Clarke, Shannon, Cook, Joseph, Cooper, Lisa, Cossette, Marie-Laurence, Day, Joanna, DeYoung, Joseph, Dirocco, Stacy, Dold, Christopher, Dunnum, Jonathan, Ehmke, Erin, Emmons, Candice, Emmrich, Stephan, Erbay, Ebru, Erlacher-Reid, Claire, Faulkes, Chris, Fei, Zhe, Ferguson, Steven, Finno, Carrie, Flower, Jennifer, Gaillard, Jean-Michel, Garde, Eva, Gerber, Livia, Gladyshev, Vadim, Goya, Rodolfo, Grant, Matthew, Green, Carla, Hanson, M, Hart, Daniel, Haulena, Martin, Herrick, Kelsey, Hogan, Andrew, Hogg, Carolyn, Hore, Timothy, Huang, Taosheng, Izpisua Belmonte, Juan, Jasinska, Anna, Jones, Gareth, Jourdain, Eve, Kashpur, Olga, Katcher, Harold, Katsumata, Etsuko, Kaza, Vimala, Kiaris, Hippokratis, Kobor, Michael, Kordowitzki, Pawel, Koski, William, Krützen, Michael, Kwon, Soo, Larison, Brenda, Lee, Sang-Goo, Lehmann, Marianne, Lemaître, Jean-François, Levine, Andrew, Li, Xinmin, Li, Cun, Lim, Andrea, Lin, David, Lindemann, Dana, Liphardt, Schuyler, Little, Thomas, Macoretta, Nicholas, Maddox, Dewey, Matkin, Craig, Mattison, Julie, McClure, Matthew, and Mergl, June
Subjects: Adult, Animals, Humans, DNA Methylation, Epigenesis, Genetic, Epigenome, Genome, Mammals, Phylogeny
Abstract: Using DNA methylation profiles (n = 15,456) from 348 mammalian species, we constructed phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using unsupervised clustering across all samples, we identified 55 distinct cytosine modules, of which 30 are related to traits such as maximum life span, adult weight, age, sex, and human mortality risk. Maximum life span is associated with methylation levels in HOXL subclass homeobox genes and developmental processes and is potentially regulated by pluripotency transcription factors. The methylation state of some modules responds to perturbations such as caloric restriction, ablation of growth hormone receptors, consumption of high-fat diets, and expression of Yamanaka factors. This study reveals an intertwined evolution of the genome and epigenome that mediates the biological characteristics and traits of different mammalian species.
Published: 2023

60. Search for sub-TeV Neutrino Emission from Novae with IceCube-DeepCore

Author: Abbasi, R, Ackermann, M, Adams, J, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Alves, AA, Amin, NM, Andeen, K, Anderson, T, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carnie-Bronca, EG, Chen, C, Chen, Z, Chirkin, D, Choi, S, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Fienberg, AT, Finley, C, Fischer, L, Fox, D, Franckowiak, A, Friedman, E, Fritz, A, and Fürst, P
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural), Astronomy & Astrophysics, Astronomical sciences, Particle and high energy physics, Space sciences
Abstract: The understanding of novae, the thermonuclear eruptions on the surfaces of white dwarf stars in binaries, has recently undergone a major paradigm shift. Though the bolometric luminosity of novae was long thought to arise directly from photons supplied by the thermonuclear runaway, recent gigaelectronvolt (GeV) gamma-ray observations have supported the notion that a significant portion of the luminosity could come from radiative shocks. More recently, observations of novae have lent evidence that these shocks are acceleration sites for hadrons for at least some types of novae. In this scenario, a flux of neutrinos may accompany the observed gamma rays. As the gamma rays from most novae have only been observed up to a few GeV, novae have previously not been considered as targets for neutrino telescopes, which are most sensitive at and above teraelectronvolt (TeV) energies. Here, we present the first search for neutrinos from novae with energies between a few GeV and 10 TeV using IceCube-DeepCore, a densely instrumented region of the IceCube Neutrino Observatory with a reduced energy threshold. We search both for a correlation between gamma-ray and neutrino emission as well as between optical and neutrino emission from novae. We find no evidence for neutrino emission from the novae considered in this analysis and set upper limits for all gamma-ray detected novae.
Published: 2023

61. Constraints on Populations of Neutrino Sources from Searches in the Directions of IceCube Neutrino Alerts

Author: Abbasi, R, Ackermann, M, Adams, J, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Alves, AA, Amin, NM, Andeen, K, Anderson, T, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, Benda, S, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carnie-Bronca, EG, Chen, C, Chen, Z, Chirkin, D, Choi, K, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Cross, R, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Fienberg, AT, Finley, C, Fischer, L, Fox, D, Franckowiak, A, and Friedman, E
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural), Astronomy & Astrophysics, Astronomical sciences, Particle and high energy physics, Space sciences
Abstract: Beginning in 2016, the IceCube Neutrino Observatory has sent out alerts in real time containing the information of high-energy (E ≳ 100 TeV) neutrino candidate events with moderate to high (≳30%) probability of astrophysical origin. In this work, we use a recent catalog of such alert events, which, in addition to events announced in real time, includes events that were identified retroactively and covers the time period of 2011-2020. We also search for additional, lower-energy neutrinos from the arrival directions of these IceCube alerts. We show how performing such an analysis can constrain the contribution of rare populations of cosmic neutrino sources to the diffuse astrophysical neutrino flux. After searching for neutrino emission coincident with these alert events on various timescales, we find no significant evidence of either minute-scale or day-scale transient neutrino emission or of steady neutrino emission in the direction of these alert events. This study also shows how numerous a population of neutrino sources has to be to account for the complete astrophysical neutrino flux. Assuming that sources have the same luminosity, an E −2.5 neutrino spectrum, and number densities that follow star formation rates, the population of sources has to be more numerous than 7 × 10−9 Mpc−3. This number changes to 3 × 10−7 Mpc−3 if number densities instead have no cosmic evolution.
Published: 2023

62. The prevalence of sleep-disordered breathing and associated risk factors in patients with decompensated congestive heart failure in Mozambique.

Author: Lo, Shelton, Mbanze, Irina, Orr, Jeremy E, DeYoung, Pamela, Checkoway, Harvey, Govo, Valerio, Jessen, Neusa, Damasceno, Albertino, and Malhotra, Atul
Subjects: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cardiovascular, Clinical Research, Sleep Research, Heart Disease, Lung, Humans, Male, Stroke Volume, Prevalence, Mozambique, Ventricular Function, Left, Sleep Apnea Syndromes, Cheyne-Stokes Respiration, Risk Factors, Heart Failure, breathing, sleep, heart failure, apnea, breath, sleep disorder, decompensated, congestive, Clinical Sciences, Other Medical and Health Sciences, Psychology, Neurology & Neurosurgery, Clinical sciences
Abstract: Study objectivesSleep-disordered breathing (SDB) is common in patients with congestive heart failure and has important implications regarding symptoms and prognosis. However, the burden of SDB on those with heart failure has not been well characterized in developing countries, including Mozambique in sub-Saharan Africa. Diagnosing SDB in individuals with congestive heart failure is important because treatment of SDB may improve outcomes.MethodsBetween September 2014 and April 2017, patients hospitalized in a specialized cardiology unit in Maputo, Mozambique with decompensated congestive heart failure were recruited using convenience sampling. We determined the prevalence of SDB and associated risk factors.ResultsA total of 165 patients were recruited, of which 145 had evaluable sleep study data. The overall prevalence of SDB in patients with decompensated congestive heart failure was 72%, and of these 46% had Cheyne-Stokes respirations. Male sex, higher body mass index, and lower left ventricular ejection fraction were all associated with a higher likelihood of SDB and more severe SDB. Cheyne-Stokes respirations were associated with male sex, lower ejection fraction, and larger left atrial size.ConclusionsWe conclude that in sub-Saharan Africa SDB is common in decompensated congestive heart failure and strongly predicted by demographic and echocardiographic parameters. This study highlights the need for the development of diagnostic tools and management strategies for patients with severe heart failure in resource-limited settings.CitationLo S, Mbanze I, Orr JE, et al. The prevalence of sleep-disordered breathing and associated risk factors in patients with decompensated congestive heart failure in Mozambique. J Clin Sleep Med. 2023;19(6):1103-1110.
Published: 2023

63. The language of sleepiness in obstructive sleep apnea beyond the Epworth

Author: Sunwoo, Bernie Y, Kaufmann, Christopher N, Murez, Andrea, Lee, Ellen, Gilbertson, Dillon, Bosompra, Naa-Oye, DeYoung, Pamela, and Malhotra, Atul
Subjects: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Lung, Clinical Research, Aging, Sleep Research, Adult, Female, Humans, Sleepiness, Disorders of Excessive Somnolence, Sleep Apnea, Obstructive, Wakefulness, Polysomnography, Surveys and Questionnaires, Excessive daytime sleepiness, Obstructive sleep apnea, Epworth Sleepiness Scale, Hypersomnolence, Fatigue, Clinical Sciences, Psychology, Respiratory System, Clinical sciences
Abstract: PurposeObstructive sleep apnea (OSA) is underdiagnosed, partially from variable clinical presentations. Emphasis is often placed on Epworth Sleepiness Scale (ESS), a subjective measure of sleepiness, but variable in OSA. We hypothesized that daytime complaints measured with Language of Sleepiness Questionnaire (LOS) in OSA are not being captured by ESS.MethodsAdults referred to a tertiary sleep clinic undergoing sleep studies completed ESS and LOS questionnaires (20 items with various patient-reported descriptors). LOS was examined in patients who had or did not have OSA without sleepiness based on ESS
Published: 2023

64. Author Correction: Precision behavioral phenotyping as a strategy for uncovering the biological correlates of psychopathology

Author: Tiego, Jeggan, Martin, Elizabeth A., DeYoung, Colin G., Hagan, Kelsey, Cooper, Samuel E., Pasion, Rita, Satchell, Liam, Shackman, Alexander J., Bellgrove, Mark A., and Fornito, Alex
Published: 2024
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65. Limits on Neutrino Emission from GRB 221009A from MeV to PeV using the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Venugopal, M., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract: Gamma-ray bursts (GRBs) have long been considered a possible source of high-energy neutrinos. While no correlations have yet been detected between high-energy neutrinos and GRBs, the recent observation of GRB 221009A - the brightest GRB observed by Fermi-GBM to date and the first one to be observed above an energy of 10 TeV - provides a unique opportunity to test for hadronic emission. In this paper, we leverage the wide energy range of the IceCube Neutrino Observatory to search for neutrinos from GRB 221009A. We find no significant deviation from background expectation across event samples ranging from MeV to PeV energies, placing stringent upper limits on the neutrino emission from this source., Comment: Revised figure 1 and table 2 accounting for missing normalization factors in the flux upper limits from the GRECO (factor 2) and ELOWEN (factor 1/3) sample. Revised figure A1 accounting for a missing factor 1/2 in the visualization of GRECO and ELOWEN effective area
Published: 2023
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66. The multi-wavelength view of shocks in the fastest nova V1674 Her

Author: Sokolovsky, K. V., Johnson, T. J., Buson, S., Jean, P., Cheung, C. C., Mukai, K., Chomiuk, L., Aydi, E., Molina, B., Kawash, A., Linford, J. D., Mioduszewski, A. J., Rupen, M. P., Sokoloski, J. L., Williams, M. N., Steinberg, E., Vurm, I., Metzger, B. D., Page, K. L., Orio, M., Quimby, R. M., Shafter, A. W., Corbett, H., Bolzoni, S., DeYoung, J., Menzies, K., Romanov, F. D., Richmond, M., Ulowetz, J., Vanmunster, T., Williamson, G., Lane, D. J., Bartnik, M., Bellaver, M., Bruinsma, E., Dugan, E., Fedewa, J., Gerhard, C., Painter, S., Peterson, D. -M., Rodriguez, J. E., Smith, C., Sullivan, H., and Watson, S.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Classical novae are shock-powered multi-wavelength transients triggered by a thermonuclear runaway on an accreting white dwarf. V1674 Her is the fastest nova ever recorded (time to declined by two magnitudes is t_2=1.1 d) that challenges our understanding of shock formation in novae. We investigate the physical mechanisms behind nova emission from GeV gamma-rays to cm-band radio using coordinated Fermi-LAT, NuSTAR, Swift and VLA observations supported by optical photometry. Fermi-LAT detected short-lived (18 h) 0.1-100 GeV emission from V1674 Her that appeared 6 h after the eruption began; this was at a level of (1.6 +/- 0.4)x10^-6 photons cm^-2 s^-1. Eleven days later, simultaneous NuSTAR and Swift X-ray observations revealed optically thin thermal plasma shock-heated to kT_shock = 4 keV. The lack of a detectable 6.7 keV Fe K_alpha emission suggests super-solar CNO abundances. The radio emission from V1674 Her was consistent with thermal emission at early times and synchrotron at late times. The radio spectrum steeply rising with frequency may be a result of either free-free absorption of synchrotron and thermal emission by unshocked outer regions of the nova shell or the Razin-Tsytovich effect attenuating synchrotron emission in dense plasma. The development of the shock inside the ejecta is unaffected by the extraordinarily rapid evolution and the intermediate polar host of this nova., Comment: 20 pages, 9 figures, 3 tables. Accepted to MNRAS
Published: 2023
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67. Do Multi-Document Summarization Models Synthesize?

Author: DeYoung, Jay, Martinez, Stephanie C., Marshall, Iain J., and Wallace, Byron C.
Subjects: Computer Science - Computation and Language
Abstract: Multi-document summarization entails producing concise synopses of collections of inputs. For some applications, the synopsis should accurately synthesize inputs with respect to a key aspect, e.g., a synopsis of film reviews written about a particular movie should reflect the average critic consensus. As a more consequential example, narrative summaries that accompany biomedical systematic reviews of clinical trial results should accurately summarize the potentially conflicting results from individual trials. In this paper we ask: To what extent do modern multi-document summarization models implicitly perform this sort of synthesis? We run experiments over opinion and evidence synthesis datasets using a suite of summarization models, from fine-tuned transformers to GPT-4. We find that existing models partially perform synthesis, but imperfectly: even the best performing models are over-sensitive to changes in input ordering and under-sensitive to changes in input compositions (e.g., ratio of positive to negative reviews). We propose a simple, general, effective method for improving model synthesis capabilities by generating an explicitly diverse set of candidate outputs, and then selecting from these the string best aligned with the expected aggregate measure for the inputs, or abstaining when the model produces no good candidate., Comment: Accepted to TACL, to be presented at ACL 2024 in Bangkok, Thailand. 9 Figures, 11 Tables, 14 pages of main content, 20 pages total. This paper has some _history_. Buy me a drink if you want to hear about it
Published: 2023

68. D-Egg: a Dual PMT Optical Module for IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carloni, K., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Domi, A., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Meures, T., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Sandstrom, P., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Shimizu, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weber, J., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wisher, I., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, F., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract: The D-Egg, an acronym for ``Dual optical sensors in an Ellipsoid Glass for Gen2,'' is one of the optical modules designed for future extensions of the IceCube experiment at the South Pole. The D-Egg has an elongated-sphere shape to maximize the photon-sensitive effective area while maintaining a narrow diameter to reduce the cost and the time needed for drilling of the deployment holes in the glacial ice for the optical modules at depths up to 2700 meters. The D-Egg design is utilized for the IceCube Upgrade, the next stage of the IceCube project also known as IceCube-Gen2 Phase 1, where nearly half of the optical sensors to be deployed are D-Eggs. With two 8-inch high-quantum efficiency photomultiplier tubes (PMTs) per module, D-Eggs offer an increased effective area while retaining the successful design of the IceCube digital optical module (DOM). The convolution of the wavelength-dependent effective area and the Cherenkov emission spectrum provides an effective photodetection sensitivity that is 2.8 times larger than that of IceCube DOMs. The signal of each of the two PMTs is digitized using ultra-low-power 14-bit analog-to-digital converters with a sampling frequency of 240 MSPS, enabling a flexible event triggering, as well as seamless and lossless event recording of single-photon signals to multi-photons exceeding 200 photoelectrons within 10 nanoseconds. Mass production of D-Eggs has been completed, with 277 out of the 310 D-Eggs produced to be used in the IceCube Upgrade. In this paper, we report the des\ ign of the D-Eggs, as well as the sensitivity and the single to multi-photon detection performance of mass-produced D-Eggs measured in a laboratory using the built-in data acquisition system in each D-Egg optical sensor module., Comment: 26 pages, 18 figures, 1 table
Published: 2022
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69. Search for sub-TeV Neutrino Emission from Novae with IceCube-DeepCore

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Diaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Nayerhoda, A., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The understanding of novae, the thermonuclear eruptions on the surfaces of white dwarf stars in binaries, has recently undergone a major paradigm shift. Though the bolometric luminosity of novae was long thought to arise directly from photons supplied by the thermonuclear runaway, recent GeV gamma-ray observations have supported the notion that a significant portion of the luminosity could come from radiative shocks. More recently, observations of novae have lent evidence that these shocks are acceleration sites for hadrons for at least some types of novae. In this scenario, a flux of neutrinos may accompany the observed gamma rays. As the gamma rays from most novae have only been observed up to a few GeV, novae have previously not been considered as targets for neutrino telescopes, which are most sensitive at and above TeV energies. Here, we present the first search for neutrinos from novae with energies between a few GeV and 10 TeV using IceCube-DeepCore, a densely instrumented region of the IceCube Neutrino Observatory with a reduced energy threshold. We search both for a correlation between gamma-ray and neutrino emission as well as between optical and neutrino emission from novae. We find no evidence for neutrino emission from the novae considered in this analysis and set upper limits for all gamma-ray detected novae., Comment: Published in ApJ. 21 pages, 11 figures. Revised figure 1, 4, 6 (left panel), 11 and table 1 accounting for missing normalization factor of 2 in the flux upper limits from the GRECO Astronomy sample. Revised figure 8 accounting for a missing factor 1/2 in the visualization of GRECO effective area
Published: 2022
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70. A Search for Coincident Neutrino Emission from Fast Radio Bursts with Seven Years of IceCube Cascade Events

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Nayerhoda, A., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: This paper presents the results of a search for neutrinos that are spatially and temporally coincident with 22 unique, non-repeating Fast Radio Bursts (FRBs) and one repeating FRB (FRB121102). FRBs are a rapidly growing class of Galactic and extragalactic astrophysical objects that are considered a potential source of high-energy neutrinos. The IceCube Neutrino Observatory's previous FRB analyses have solely used track events. This search utilizes seven years of IceCube's cascade events which are statistically independent of the track events. This event selection allows probing of a longer range of extended timescales due to the low background rate. No statistically significant clustering of neutrinos was observed. Upper limits are set on the time-integrated neutrino flux emitted by FRBs for a range of extended time-windows.
Published: 2022
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71. Data Layout from a Type-Theoretic Perspective

Author: DeYoung, Henry and Pfenning, Frank
Subjects: Computer Science - Logic in Computer Science, Computer Science - Programming Languages
Abstract: The specifics of data layout can be important for the efficiency of functional programs and interaction with external libraries. In this paper, we develop a type-theoretic approach to data layout that could be used as a typed intermediate language in a compiler or to give a programmer more control. Our starting point is a computational interpretation of the semi-axiomatic sequent calculus for intuitionistic logic that defines abstract notions of cells and addresses. We refine this semantics so addresses have more structure to reflect possible alternative layouts without fundamentally departing from intuitionistic logic. We then add recursive types and explore example programs and properties of the resulting language., Comment: Invited paper for MFPS 2022 special issue of ENTICS
Published: 2022
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72. Testing secondary sex ratio bias hypotheses in white‐tailed deer in Mississippi, USA

Author: Jane E. Dentinger, Lacy A. Dolan Todt, Emma A. Schultz, James N. Helferich, Stephen Demarais, Randy W. DeYoung, William T. McKinley, Bronson K. Strickland, and Melanie R. Boudreau
Subjects: Fisherian frequency dependence, local resource competition hypothesis, Odocoileus virginianus, Trivers–Willard hypothesis, Ecology, QH540-549.5
Abstract: Abstract Natural selection favors individuals with the highest inclusive fitness (i.e., total number of descendants). In cases where one sex is more productive, one or both parents may maximize their inclusive fitness by investing in the offspring of the more prolific sex. Such preferential production can lead to skewed sex ratios at various life history stages, including at birth, resulting in secondary sex ratio bias. Several competing hypotheses have been proposed to explain observed variation in secondary sex ratios including Fisher's frequency dependence and two hypotheses related to maternal condition: Trivers–Willard and the local resource hypotheses. Although it has been shown that maternal condition can influence the number of offspring produced in white‐tailed deer, there is no consensus as to which of the hypotheses drives sex ratio bias in wild populations. Using a spatiotemporally extensive dataset of pregnant white‐tailed deer from Mississippi, USA, we examined fetal sex ratio in relation to the Fisherian frequency‐dependence hypothesis and hypotheses related to maternal condition. While there was a male‐sex ratio bias in pregnant females that reduced in intensity with the number of offspring, there was no support for condition‐related hypotheses. Instead, secondary sex ratios for white‐tailed deer in Mississippi were nearly consistent with Fisherian frequency dependence. Our findings add to the body of literature on secondary sex biases in white‐tailed deer and help inform sex bias ratios for a southern population of a cervid of management importance in the US.
Published: 2024
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73. Constraining High-energy Neutrino Emission from Supernovae with IceCube

Author: Abbasi, R, Ackermann, M, Adams, J, Agarwalla, SK, Aguilar, JA, Ahlers, M, Alameddine, JM, Amin, NM, Andeen, K, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Butterfield, D, Campana, MA, Carloni, K, Carnie-Bronca, EG, Chattopadhyay, S, Chen, C, Chen, Z, Chirkin, D, Choi, S, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Domi, A, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fang, K, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Finley, C, Fischer, L, Fox, D, Franckowiak, A, Friedman, E, Fritz, A, and Fürst, P
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Astronomy & Astrophysics, Astronomical sciences, Space sciences
Abstract: Core-collapse supernovae are a promising potential high-energy neutrino source class. We test for correlation between seven years of IceCube neutrino data and a catalog containing more than 1000 core-collapse supernovae of types IIn and IIP and a sample of stripped-envelope supernovae. We search both for neutrino emission from individual supernovae as well as for combined emission from the whole supernova sample, through a stacking analysis. No significant spatial or temporal correlation of neutrinos with the cataloged supernovae was found. All scenarios were tested against the background expectation and together yield an overall p-value of 93%; therefore, they show consistency with the background only. The derived upper limits on the total energy emitted in neutrinos are 1.7 × 1048 erg for stripped-envelope supernovae, 2.8 × 1048 erg for type IIP, and 1.3 × 1049 erg for type IIn SNe, the latter disfavoring models with optimistic assumptions for neutrino production in interacting supernovae. We conclude that stripped-envelope supernovae and supernovae of type IIn do not contribute more than 14.6% and 33.9%, respectively, to the diffuse neutrino flux in the energy range of about [ 103-105] GeV, assuming that the neutrino energy spectrum follows a power-law with an index of −2.5. Under the same assumption, we can only constrain the contribution of type IIP SNe to no more than 59.9%. Thus, core-collapse supernovae of types IIn and stripped-envelope supernovae can both be ruled out as the dominant source of the diffuse neutrino flux under the given assumptions.
Published: 2023

74. The impact of sleep disordered breathing on cardiac troponin in acutely decompensated heart failure

Author: Light, Matthew P, Kreitinger, Kimberly Y, Lee, Euyhyun, DeYoung, Pamela N, Lakhani, Avni, Siegel, Brent, Daniels, Lori B, Malhotra, Atul, and Owens, Robert L
Subjects: Biomedical and Clinical Sciences, Medical Physiology, Cardiovascular Medicine and Haematology, Clinical Research, Aging, Heart Disease, Lung, Cardiovascular, Sleep Research, Adult, Humans, Sleep Apnea, Central, Sleep Apnea Syndromes, Sleep, Polysomnography, Heart Failure, Sleep apnea, Heart failure, Troponin, Cheyne-Stokes, Clinical Sciences, Psychology, Respiratory System, Clinical sciences
Abstract: PurposeSleep disordered breathing in decompensated heart failure has physiological consequences (e.g., intermittent hypoxemia) that may predispose to subclinical myocardial injury, yet a temporal relationship between sleep apnea and troponin elevation has not been established.MethodsWe assessed the feasibility of performing respiratory polygraphy and measuring overnight high-sensitivity cardiac troponin T change in adults admitted to the hospital with acutely decompensated heart failure. Repeat sleep apnea tests (SATs) were performed to determine response to optimal medical heart failure therapy. Multivariable logistic regression was used to identify associations between absolute overnight troponin change and sleep apnea characteristics.ResultsAmong the 19 subjects with acutely decompensated heart failure, 92% of SATs demonstrated sleep disordered breathing (apnea-hypopnea index [AHI] > 5 events/h). For those with repeat SATs, AHI increased in 67% despite medical management of heart failure. Overnight troponin increase was associated with moderate to severe sleep apnea (vs. no to mild sleep apnea, odds ratio (OR = 18.4 [1.51-224.18]), central apnea index (OR = 1.11 [1.01-1.22]), and predominantly central sleep apnea (vs. obstructive, OR = 22.9 [1.29-406.32]).ConclusionsSleep apnea severity and a central apnea pattern may be associated with myocardial injury. Respiratory polygraphy with serial biomarker assessment is feasible in this population, and combining this approach with interventions (e.g., positive airway pressure) may help establish if a link exists between sleep apnea and subclinical myocardial injury.
Published: 2023

75. D-Egg: a dual PMT optical module for IceCube

Author: Abbasi, R, Ackermann, M, Adams, J, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Alves, AA, Amin, NM, Andeen, K, Anderson, T, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carnie-Bronca, EG, Chen, C, Chen, Z, Chirkin, D, Choi, S, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Fienberg, AT, Finley, C, Fischer, L, Fox, D, Franckowiak, A, Friedman, E, Fritz, A, and Fürst, P
Subjects: Engineering, Electronics, Sensors and Digital Hardware, Physical Sciences, Cherenkov detectors, Detectors for UV, visible and IR photons, Neutrino detectors, Nuclear & Particles Physics, Physical sciences
Abstract: The D-Egg, an acronym for "Dual optical sensors in an Ellipsoid Glass for Gen2,"is one of the optical modules designed for future extensions of the IceCube experiment at the South Pole. The D-Egg has an elongated-sphere shape to maximize the photon-sensitive effective area while maintaining a narrow diameter to reduce the cost and the time needed for drilling of the deployment holes in the glacial ice for the optical modules at depths up to 2700 m. The D-Egg design is utilized for the IceCube Upgrade, the next stage of the IceCube project also known as IceCube-Gen2 Phase 1, where nearly half of the optical sensors to be deployed are D-Eggs. With two 8-inch high-quantum efficiency photomultiplier tubes (PMTs) per module, D-Eggs offer an increased effective area while retaining the successful design of the IceCube digital optical module (DOM). The convolution of the wavelength-dependent effective area and the Cherenkov emission spectrum provides an effective photodetection sensitivity that is 2.8 times larger than that of IceCube DOMs. The signal of each of the two PMTs is digitized using ultra-low-power 14-bit analog-to-digital converters with a sampling frequency of 240 MSPS, enabling a flexible event triggering, as well as seamless and lossless event recording of single-photon signals to multi-photons exceeding 200 photoelectrons within 10 ns. Mass production of D-Eggs has been completed, with 277 out of the 310 D-Eggs produced to be used in the IceCube Upgrade. In this paper, we report the design of the D-Eggs, as well as the sensitivity and the single to multi-photon detection performance of mass-produced D-Eggs measured in a laboratory using the built-in data acquisition system in each D-Egg optical sensor module.
Published: 2023

76. Limits on Neutrino Emission from GRB 221009A from MeV to PeV Using the IceCube Neutrino Observatory

Author: Abbasi, R, Ackermann, M, Adams, J, Agarwalla, SK, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Amin, NM, Andeen, K, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carloni, K, Carnie-Bronca, EG, Chen, C, Chen, Z, Chirkin, D, Choi, S, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Domi, A, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Finley, C, Fischer, L, Fox, D, Franckowiak, A, Friedman, E, Fritz, A, and Fürst, P
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Astronomical and Space Sciences, Astronomy & Astrophysics, Astronomical sciences, Space sciences
Abstract: Gamma-ray bursts (GRBs) have long been considered a possible source of high-energy neutrinos. While no correlations have yet been detected between high-energy neutrinos and GRBs, the recent observation of GRB 221009A—the brightest GRB observed by Fermi-GBM to date and the first one to be observed above an energy of 10 TeV—provides a unique opportunity to test for hadronic emission. In this paper, we leverage the wide energy range of the IceCube Neutrino Observatory to search for neutrinos from GRB 221009A. We find no significant deviation from background expectation across event samples ranging from MeV to PeV energies, placing stringent upper limits on the neutrino emission from this source.
Published: 2023

77. Searches for Neutrinos from Large High Altitude Air Shower Observatory Ultra-high-energy γ-Ray Sources Using the IceCube Neutrino Observatory

Author: Abbasi, R, Ackermann, M, Adams, J, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Alves, AA, Amin, NM, Andeen, K, Anderson, T, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, V., A Balagopal, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, Benda, S, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Meneguolo, C Boscolo, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carnie-Bronca, EG, Chang, YL, Chen, C, Chen, Z, Chirkin, D, Choi, K, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Fienberg, AT, Finley, C, Fischer, L, Fox, D, Franckowiak, A, and Friedman, E
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Astronomical Sciences, Physical Sciences, Astronomical and Space Sciences, Astronomy & Astrophysics, Astronomical sciences, Space sciences
Abstract: Galactic PeV cosmic-ray accelerators (PeVatrons) are Galactic sources theorized to accelerate cosmic rays up to PeV in energy. The accelerated cosmic rays are expected to interact hadronically with nearby ambient gas or the interstellar medium, resulting in γ-rays and neutrinos. Recently, the Large High Altitude Air Shower Observatory (LHAASO) identified 12 γ-ray sources with emissions above 100 TeV, making them candidates for PeVatrons. While at these high energies the Klein-Nishina effect exponentially suppresses leptonic emission from Galactic sources, evidence for neutrino emission would unequivocally confirm hadronic acceleration. Here, we present the results of a search for neutrinos from these γ-ray sources and stacking searches testing for excess neutrino emission from all 12 sources as well as their subcatalogs of supernova remnants and pulsar wind nebulae with 11 yr of track events from the IceCube Neutrino Observatory. No significant emissions were found. Based on the resulting limits, we place constraints on the fraction of γ-ray flux originating from the hadronic processes in the Crab Nebula and LHAASO J2226+6057.
Published: 2023

78. Searches for Neutrinos from LHAASO ultra-high-energy {\gamma}-ray sources using the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chang, Y. L., Chen, C., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griffin, S., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., DeHolton, K. Leonard, Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Merten, L., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Nayerhoda, A., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rameez, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaufel, M., Schieler, H., Schindler, S., Schlueter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, D. L., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Galactic PeVatrons are Galactic sources theorized to accelerate cosmic rays up to PeV in energy. The accelerated cosmic rays are expected to interact hadronically with nearby ambient gas or the interstellar medium, resulting in {\gamma}-rays and neutrinos. Recently, the Large High Altitude Air Shower Observatory (LHAASO) identified 12 {\gamma}-ray sources with emissions above 100 TeV, making them candidates for PeV cosmic-ray accelerators (PeVatrons). While at these high energies the Klein-Nishina effect suppresses exponentially leptonic emission from Galactic sources, evidence for neutrino emission would unequivocally confirm hadronic acceleration. Here, we present the results of a search for neutrinos from these {\gamma}-ray sources and stacking searches testing for excess neutrino emission from all 12 sources as well as their subcatalogs of supernova remnants and pulsar wind nebulae with 11 years of track events from the IceCube Neutrino Observatory. No significant emissions were found. Based on the resulting limits, we place constraints on the fraction of {\gamma}-ray flux originating from the hadronic processes in the Crab Nebula and LHAASOJ2226+6057.
Published: 2022
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79. Evidence for neutrino emission from the nearby active galaxy NGC 1068

Author: IceCube Collaboration, Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alispach, C., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barbano, A., Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Boddenberg, M., Bontempo, F., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Browne, S., Burgman, A., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Dvorak, E., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Filimonov, K., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goldschmidt, A., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoffmann, R., Hokanson-Fasig, B., Hoshina, K., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mariş, I. C., Martinez-Soler, I., Maruyama, R., Mase, K., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Naab, R., Nagai, R., Nahnhauer, R., Naumann, U., Necker, J., Nguyên, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Nygren, D., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pittermann, M., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Price, P. B., Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rehman, A., Reichherzer, P., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Herrera, S. E. Sanchez, Sandrock, A., Sandroos, J., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Steuer, A., Stezelberger, T., Stokstad, R., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Tilav, S., Tischbein, F., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Verpoest, S., Walck, C., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Wolf, M., Woschnagg, K., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Astrophysics of Galaxies, Astrophysics - Instrumentation and Methods for Astrophysics, High Energy Physics - Experiment
Abstract: We report three searches for high energy neutrino emission from astrophysical objects using data recorded with IceCube between 2011 and 2020. Improvements over previous work include new neutrino reconstruction and data calibration methods. In one search, the positions of 110 a priori selected gamma-ray sources were analyzed individually for a possible surplus of neutrinos over atmospheric and cosmic background expectations. We found an excess of $79_{-20}^{+22}$ neutrinos associated with the nearby active galaxy NGC 1068 at a significance of 4.2$\,\sigma$. The excess, which is spatially consistent with the direction of the strongest clustering of neutrinos in the Northern Sky, is interpreted as direct evidence of TeV neutrino emission from a nearby active galaxy. The inferred flux exceeds the potential TeV gamma-ray flux by at least one order of magnitude., Comment: Minor adjustment to the pdf metadata. Paper content remains unchanged. For the published version of this article visit the Science web portal: https://www.science.org/doi/10.1126/science.abg3395 , or the IceCube database (no subscription needed): https://icecube.wisc.edu/science/publications/
Published: 2022
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80. Constraints on populations of neutrino sources from searches in the directions of IceCube neutrino alerts

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Nayerhoda, A., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Noell, A., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rameez, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Schaufel, M., Schieler, H., Schindler, S., Schlueter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Beginning in 2016, the IceCube Neutrino Observatory has sent out alerts in real time containing the information of high-energy ($E \gtrsim 100$~TeV) neutrino candidate events with moderate-to-high ($\gtrsim 30$\%) probability of astrophysical origin. In this work, we use a recent catalog of such alert events, which, in addition to events announced in real-time, includes events that were identified retroactively, and covers the time period of 2011-2020. We also search for additional, lower-energy, neutrinos from the arrival directions of these IceCube alerts. We show how performing such an analysis can constrain the contribution of rare populations of cosmic neutrino sources to the diffuse astrophysical neutrino flux. After searching for neutrino emission coincident with these alert events on various timescales, we find no significant evidence of either minute-scale or day-scale transient neutrino emission or of steady neutrino emission in the direction of these alert events. This study also shows how numerous a population of neutrino sources has to be to account for the complete astrophysical neutrino flux. Assuming sources have the same luminosity, an $E^{-2.5}$ neutrino spectrum and number densities that follow star-formation rates, the population of sources has to be more numerous than $7\times 10^{-9}~\textrm{Mpc}^{-3}$. This number changes to $3\times 10^{-7}~\textrm{Mpc}^{-3}$ if number densities instead have no cosmic evolution., Comment: 22 pages, 9 figures 2 Tables
Published: 2022
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81. Graph Neural Networks for Low-Energy Event Classification & Reconstruction in IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Gray, S. J., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Nayerhoda, A., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Petersen, T. C., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rameez, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Schaufel, M., Schieler, H., Schindler, S., Schlueter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: High Energy Physics - Experiment, Astrophysics - Instrumentation and Methods for Astrophysics, Computer Science - Machine Learning, Physics - Data Analysis, Statistics and Probability, Physics - Instrumentation and Detectors
Abstract: IceCube, a cubic-kilometer array of optical sensors built to detect atmospheric and astrophysical neutrinos between 1 GeV and 1 PeV, is deployed 1.45 km to 2.45 km below the surface of the ice sheet at the South Pole. The classification and reconstruction of events from the in-ice detectors play a central role in the analysis of data from IceCube. Reconstructing and classifying events is a challenge due to the irregular detector geometry, inhomogeneous scattering and absorption of light in the ice and, below 100 GeV, the relatively low number of signal photons produced per event. To address this challenge, it is possible to represent IceCube events as point cloud graphs and use a Graph Neural Network (GNN) as the classification and reconstruction method. The GNN is capable of distinguishing neutrino events from cosmic-ray backgrounds, classifying different neutrino event types, and reconstructing the deposited energy, direction and interaction vertex. Based on simulation, we provide a comparison in the 1-100 GeV energy range to the current state-of-the-art maximum likelihood techniques used in current IceCube analyses, including the effects of known systematic uncertainties. For neutrino event classification, the GNN increases the signal efficiency by 18% at a fixed false positive rate (FPR), compared to current IceCube methods. Alternatively, the GNN offers a reduction of the FPR by over a factor 8 (to below half a percent) at a fixed signal efficiency. For the reconstruction of energy, direction, and interaction vertex, the resolution improves by an average of 13%-20% compared to current maximum likelihood techniques in the energy range of 1-30 GeV. The GNN, when run on a GPU, is capable of processing IceCube events at a rate nearly double of the median IceCube trigger rate of 2.7 kHz, which opens the possibility of using low energy neutrinos in online searches for transient events., Comment: Prepared for submission to JINST
Published: 2022
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82. The Impacts of Legalization of Physician-Assisted Suicide on Binge Drinking Among US Adults

Author: Suzuki, Emily, Nawa, Nobutoshi, Matsuyama, Yusuke, DeYoung, Kyle, and Fujiwara, Takeo
Published: 2023
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83. Ophthalmology procedure trends in the United States during the COVID-19 pandemic

Author: DeYoung, Charles, Asahi, Masumi G., Rosenberg, Sedona, Pakhchanian, Haig, Liu, Ivan Z., Bellur, Sunil, Raiker, Rahul, and Dalal, Monica
Published: 2023
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84. Optimization of plasma-based BioID identifies plasminogen as a ligand of ADAMTS13

Author: Hasam Madarati, Veronica DeYoung, Kanwal Singh, Taylor Sparring, Andrew C. Kwong, James C. Fredenburgh, Cherie Teney, Marlys L. Koschinsky, Michael B. Boffa, Jeffrey I. Weitz, and Colin A. Kretz
Subjects: ADAMTS13, BioID, Plasminogen, Von Willebrand factor, Medicine, Science
Abstract: Abstract ADAMTS13, a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13, regulates the length of Von Willebrand factor (VWF) multimers and their platelet-binding activity. ADAMTS13 is constitutively secreted as an active protease and is not inhibited by circulating protease inhibitors. Therefore, the mechanisms that regulate ADAMTS13 protease activity are unknown. We performed an unbiased proteomics screen to identify ligands of ADAMTS13 by optimizing the application of BioID to plasma. Plasma BioID identified 5 plasma proteins significantly labeled by the ADAMTS13-birA* fusion, including VWF and plasminogen. Glu-plasminogen, Lys-plasminogen, mini-plasminogen, and apo(a) bound ADAMTS13 with high affinity, whereas micro-plasminogen did not. None of the plasminogen variants or apo(a) bound to a C-terminal truncation variant of ADAMTS13 (MDTCS). The binding of plasminogen to ADAMTS13 was attenuated by tranexamic acid or ε-aminocaproic acid, and tranexamic acid protected ADAMTS13 from plasmin degradation. These data demonstrate that plasminogen is an important ligand of ADAMTS13 in plasma by binding to the C-terminus of ADAMTS13. Plasmin proteolytically degrades ADAMTS13 in a lysine-dependent manner, which may contribute to its regulation. Adapting BioID to identify protein-interaction networks in plasma provides a powerful new tool to study protease regulation in the cardiovascular system.
Published: 2024
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85. IceCube search for neutrinos coincident with gravitational wave events from LIGO/Virgo run O3

Author: Abbasi, R., Ackermann, M., Adams, J., Aggarwal, N., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Asali, Y., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Countryman, S., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Heuermann, L., Hickford, S., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Love, C., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Neumann, M., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Rameez, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Schaufel, M., Schieler, H., Schindler, S., Schlueter, B., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Oliveira, A. C. Silva, Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, A. G., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tung, C. F., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Veitch-Michaelis, J., Verpoest, S., Veske, D., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Using data from the IceCube Neutrino Observatory, we searched for high-energy neutrino emission from the gravitational-wave events detected by advanced LIGO and Virgo detectors during their third observing run. We did a low-latency follow-up on the public candidate events released during the detectors' third observing run and an archival search on the 80 confident events reported in GWTC-2.1 and GWTC-3 catalogs. An extended search was also conducted for neutrino emission on longer timescales from neutron star containing mergers. Follow-up searches on the candidate optical counterpart of GW190521 were also conducted. We used two methods; an unbinned maximum likelihood analysis and a Bayesian analysis using astrophysical priors, both of which were previously used to search for high-energy neutrino emission from gravitational-wave events. No significant neutrino emission was observed by any analysis and upper limits were placed on the time-integrated neutrino flux as well as the total isotropic equivalent energy emitted in high-energy neutrinos.
Published: 2022
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86. Entity Anchored ICD Coding

Author: DeYoung, Jay, Shing, Han-Chin, Kong, Luyang, Winestock, Christopher, and Shivade, Chaitanya
Subjects: Computer Science - Machine Learning, Computer Science - Computation and Language
Abstract: Medical coding is a complex task, requiring assignment of a subset of over 72,000 ICD codes to a patient's notes. Modern natural language processing approaches to these tasks have been challenged by the length of the input and size of the output space. We limit our model inputs to a small window around medical entities found in our documents. From those local contexts, we build contextualized representations of both ICD codes and entities, and aggregate over these representations to form document-level predictions. In contrast to existing methods which use a representation fixed either in size or by codes seen in training, we represent ICD codes by encoding the code description with local context. We discuss metrics appropriate to deploying coding systems in practice. We show that our approach is superior to existing methods in both standard and deployable measures, including performance on rare and unseen codes., Comment: Accepted to American Medical Informatics Association (AMIA) 2022 Annual Symposium
Published: 2022

87. Search for Astrophysical Neutrinos from 1FLE Blazars with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Hettinger, E. C., Heuermann, L., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Sogaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Elorrieta, M. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The majority of astrophysical neutrinos have undetermined origins. The IceCube Neutrino Observatory has observed astrophysical neutrinos but has not yet identified their sources. Blazars are promising source candidates, but previous searches for neutrino emission from populations of blazars detected in $\gtrsim$ GeV gamma-rays have not observed any significant neutrino excess. Recent findings in multi-messenger astronomy indicate that high-energy photons, co-produced with high-energy neutrinos, are likely to be absorbed and reemitted at lower energies. Thus, lower-energy photons may be better indicators of TeV-PeV neutrino production. This paper presents the first time-integrated stacking search for astrophysical neutrino emission from MeV-detected blazars in the first Fermi-LAT low energy catalog (1FLE) using ten years of IceCube muon-neutrino data. The results of this analysis are found to be consistent with a background-only hypothesis. Assuming an E$^{-2}$ neutrino spectrum and proportionality between the blazars' MeV gamma-ray fluxes and TeV-PeV neutrino flux, the upper limit on the 1FLE blazar energy-scaled neutrino flux is determined to be $1.64 \times 10^{-12}$ TeV cm$^{-2}$ s$^{-1}$ at 90% confidence level. This upper limit is approximately 1% of IceCube's diffuse muon-neutrino flux measurement., Comment: 13 pages, 3 figures, 1 table; to be published in Astrophysical Journal
Published: 2022
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88. Searching for High-Energy Neutrino Emission from Galaxy Clusters with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Hettinger, E. C., Heuermann, L., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Sogaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Elorrieta, M. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: Galaxy clusters have the potential to accelerate cosmic rays (CRs) to ultra-high energies via accretion shocks or embedded CR acceleration sites. CRs with energies below the Hillas condition will be confined within the cluster and will eventually interact with the intracluster medium (ICM) gas to produce secondary neutrinos and $\gamma$ rays. Using 9.5 years of muon-neutrino track events from the IceCube Neutrino Observatory, we report the results of a stacking analysis of 1094 galaxy clusters, with masses $\gtrsim 10^{14}$ $\textup{M}_\odot$ and redshifts between 0.01 and $\sim$1, detected by the {\it Planck} mission via the Sunyaev-Zeldovich (SZ) effect. We find no evidence for significant neutrino emission and report upper limits on the cumulative unresolved neutrino flux from massive galaxy clusters after accounting for the completeness of the catalog up to a redshift of 2, assuming three different weighting scenarios for the stacking and three different power-law spectra. Weighting the sources according to mass and distance, we set upper limits at $90\%$ confidence level that constrain the flux of neutrinos from massive galaxy clusters ($\gtrsim 10^{14}$ $\textup{M}_\odot$) to be no more than $4.6\%$ of the diffuse IceCube observations at 100~TeV, assuming an unbroken $E^{-2.5}$ power-law spectrum., Comment: 12 pages, 3 figures and one table. Updated with accepted version
Published: 2022
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89. IceCube Search for Neutrinos Coincident with Gravitational Wave Events from LIGO/Virgo Run O3

Author: Abbasi, R, Ackermann, M, Adams, J, Aggarwal, N, Aguilar, JA, Ahlers, M, Ahrens, M, Alameddine, JM, Alves, AA, Amin, NM, Andeen, K, Anderson, T, Anton, G, Argüelles, C, Asali, Y, Ashida, Y, Athanasiadou, S, Axani, S, Bai, X, V., A Balagopal, Baricevic, M, Bartos, I, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Tjus, J Becker, Beise, J, Bellenghi, C, Benda, S, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Bradascio, F, Braun, J, Brinson, B, Bron, S, Brostean-Kaiser, J, Burley, RT, Busse, RS, Campana, MA, Carnie-Bronca, EG, Chen, C, Chen, Z, Chirkin, D, Choi, K, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, ST, Cowen, DF, Cross, R, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, López, D Delgado, Dembinski, H, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Fienberg, AT, and Finley, C
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Astronomical Sciences, Physical Sciences, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural), Astronomy & Astrophysics, Astronomical sciences, Particle and high energy physics, Space sciences
Abstract: Using data from the IceCube Neutrino Observatory, we searched for high-energy neutrino emission from the gravitational-wave events detected by the advanced LIGO and Virgo detectors during their third observing run. We did a low-latency follow-up on the public candidate events released during the detectors' third observing run and an archival search on the 80 confident events reported in the GWTC-2.1 and GWTC-3 catalogs. An extended search was also conducted for neutrino emission on longer timescales from neutron star containing mergers. Follow-up searches on the candidate optical counterpart of GW190521 were also conducted. We used two methods; an unbinned maximum likelihood analysis and a Bayesian analysis using astrophysical priors, both of which were previously used to search for high-energy neutrino emission from gravitational-wave events. No significant neutrino emission was observed by any analysis, and upper limits were placed on the time-integrated neutrino flux as well as the total isotropic equivalent energy emitted in high-energy neutrinos.
Published: 2023

90. Observation of seasonal variations of the flux of high-energy atmospheric neutrinos with IceCube

Author: Abbasi, R, Ackermann, M, Adams, J, Agarwalla, SK, Aggarwal, N, Aguilar, JA, Ahlers, M, Alameddine, JM, Amin, NM, Andeen, K, Anton, G, Argüelles, C, Ashida, Y, Athanasiadou, S, Axani, SN, Bai, X, Balagopal V., A, Baricevic, M, Barwick, SW, Basu, V, Bay, R, Beatty, JJ, Becker, K-H, Becker Tjus, J, Beise, J, Bellenghi, C, BenZvi, S, Berley, D, Bernardini, E, Besson, DZ, Binder, G, Bindig, D, Blaufuss, E, Blot, S, Bontempo, F, Book, JY, Borowka, J, Boscolo Meneguolo, C, Böser, S, Botner, O, Böttcher, J, Bourbeau, E, Braun, J, Brinson, B, Brostean-Kaiser, J, Burley, RT, Busse, RS, Butterfield, D, Campana, MA, Carloni, K, Carnie-Bronca, EG, Chattopadhyay, S, Chen, C, Chen, Z, Chirkin, D, Choi, S, Clark, BA, Classen, L, Coleman, A, Collin, GH, Connolly, A, Conrad, JM, Coppin, P, Correa, P, Countryman, S, Cowen, DF, Dappen, C, Dave, P, De Clercq, C, DeLaunay, JJ, Delgado López, D, Dembinski, H, Deng, S, Deoskar, K, Desai, A, Desiati, P, de Vries, KD, de Wasseige, G, DeYoung, T, Diaz, A, Díaz-Vélez, JC, Dittmer, M, Domi, A, Dujmovic, H, DuVernois, MA, Ehrhardt, T, Eller, P, Engel, R, Erpenbeck, H, Evans, J, Evenson, PA, Fan, KL, Fang, K, Fazely, AR, Fedynitch, A, Feigl, N, Fiedlschuster, S, Finley, C, Fischer, L, and Fox, D
Subjects: Nuclear and Plasma Physics, Particle and High Energy Physics, Physical Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Quantum Physics, Nuclear & Particles Physics, Astronomical sciences, Atomic, molecular and optical physics, Particle and high energy physics
Abstract: Atmospheric muon neutrinos are produced by meson decays in cosmic-ray-induced air showers. The flux depends on meteorological quantities such as the air temperature, which affects the density of air. Competition between decay and re-interaction of those mesons in the first particle production generations gives rise to a higher neutrino flux when the air density in the stratosphere is lower, corresponding to a higher temperature. A measurement of a temperature dependence of the atmospheric νμ flux provides a novel method for constraining hadronic interaction models of air showers. It is particularly sensitive to the production of kaons. Studying this temperature dependence for the first time requires a large sample of high-energy neutrinos as well as a detailed understanding of atmospheric properties. We report the significant (>10σ) observation of a correlation between the rate of more than 260,000 neutrinos, detected by IceCube between 2012 and 2018, and atmospheric temperatures of the stratosphere, measured by the Atmospheric Infrared Sounder (AIRS) instrument aboard NASA’s AQUA satellite. For the observed 10 % seasonal change of effective atmospheric temperature we measure a 3.5(3) % change in the muon neutrino flux. This observed correlation deviates by about 2-3 standard deviations from the expected correlation of 4.3 % as obtained from theoretical predictions under the assumption of various hadronic interaction models.
Published: 2023

91. Acute nicotine abstinence amplifies subjective withdrawal symptoms and threat-evoked fear and anxiety, but not extended amygdala reactivity

Author: Kim, Hyung Cho, Kaplan, Claire M, Islam, Samiha, Anderson, Allegra S, Piper, Megan E, Bradford, Daniel E, Curtin, John J, DeYoung, Kathryn A, Smith, Jason F, Fox, Andrew S, and Shackman, Alexander J
Subjects: Biological Psychology, Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Psychology, Substance Misuse, Neurosciences, Tobacco Smoke and Health, Behavioral and Social Science, Prevention, Mental Health, Drug Abuse (NIDA only), Tobacco, Good Health and Well Being, Humans, Amygdala, Anxiety, Fear, Nicotine, Septal Nuclei, Substance Withdrawal Syndrome, General Science & Technology
Abstract: Tobacco smoking imposes a staggering burden on public health, underscoring the urgency of developing a deeper understanding of the processes that maintain addiction. Clinical and experience-sampling data highlight the importance of anxious withdrawal symptoms, but the underlying neurobiology has remained elusive. Mechanistic work in animals implicates the central extended amygdala (EAc)-including the central nucleus of the amygdala and the neighboring bed nucleus of the stria terminalis-but the translational relevance of these discoveries remains unexplored. Here we leveraged a randomized trial design, well-established threat-anticipation paradigm, and multidimensional battery of assessments to understand the consequences of 24-hour nicotine abstinence. The threat-anticipation paradigm had the expected consequences, amplifying subjective distress and arousal, and recruiting the canonical threat-anticipation network. Abstinence increased smoking urges and withdrawal symptoms, and potentiated threat-evoked distress, but had negligible consequences for EAc threat reactivity, raising questions about the translational relevance of prominent animal and human models of addiction. These observations provide a framework for conceptualizing nicotine abstinence and withdrawal, with implications for basic, translational, and clinical science.
Published: 2023

92. Time of day, time of sleep, and time on task effects on sleepiness and cognitive performance of bus drivers

Author: Maghsoudipour, Maryam, Moradi, Ramin, Moghimi, Sara, Ancoli-Israel, Sonia, DeYoung, Pamela N, and Malhotra, Atul
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Sleep Research, Behavioral and Social Science, Clinical Research, Good Health and Well Being, Humans, Automobile Driving, Cognition, Prospective Studies, Psychomotor Performance, Sleep, Sleepiness, Work Schedule Tolerance, Time Factors, Working memory, Driver, Shift work, Psychology, Respiratory System, Clinical sciences
Abstract: PurposeOptimal cognitive performance might prevent vehicle accidents. Identifying time-related circadian and homeostatic parameters having an impact on cognitive performance of drivers may be crucial to optimize drivers' performance.MethodsIn this prospective study conducted on bus drivers, two drivers alternated driving during a 24-h round trip and were accompanied by an interviewer. Each driver was tested using Karolinska Sleepiness Scale (KSS) and the reversed digit span Wechsler Working Memory test before the start of his shift and then every 6 h during a "work/driving" day. Psychomotor Vigilance Task (PVT) was assessed before and after the journey. Linear mixed model was used to explore the factors affecting cognitive performance and sleepiness in univariate and multivariate analysis.ResultsAmong 35 bus drivers, the effect of time of day on working memories was statistically significant (p = 0.001), with the lowest working memory scores at 04:00 am (± 1). The highest score of subjective sleepiness was also at 04:00 am (± 1). The time on task parameter affected sleepiness significantly (p = 0.024) and sleepiness was significantly associated with decreased working memory. Psychomotor Vigilance Task reaction time mean and the number of minor lapses were significantly increased after the journey, which suggested decreased vigilance. In multivariable analysis, a longer interval between the beginning of working hours and testing time (B (95% CI) = 15.25 (0.49 to 30), p = 0.043) was associated with higher (i.e., slower) PVT reaction time mean.ConclusionsThese results suggest that optimizing bus drivers' working schedules may improve drivers' sleepiness and cognitive performance and thus increase road safety.
Published: 2022

93. Point-of-care prediction model of loop gain in patients with obstructive sleep apnea: development and validation

Author: Schmickl, Christopher N, Orr, Jeremy E, Kim, Paul, Nokes, Brandon, Sands, Scott, Manoharan, Sreeganesh, McGinnis, Lana, Parra, Gabriela, DeYoung, Pamela, Owens, Robert L, and Malhotra, Atul
Subjects: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Lung, Sleep Research, Bioengineering, Adult, Cohort Studies, Humans, Point-of-Care Systems, Polysomnography, Retrospective Studies, Sleep Apnea, Obstructive, Clinical decision rules, Sleep apnea, obstructive, Respiration, Precision medicine, Sleep apnea, obstructive, Cardiorespiratory Medicine and Haematology, Respiratory System, Cardiovascular medicine and haematology
Abstract: BackgroundHigh loop gain (unstable ventilatory control) is an important-but difficult to measure-contributor to obstructive sleep apnea (OSA) pathogenesis, predicting OSA sequelae and/or treatment response. Our objective was to develop and validate a clinical prediction tool of loop gain.MethodsA retrospective cohort of consecutive adults with OSA (apnea-hypopnea index, AHI > 5/hour) based on in-laboratory polysomnography 01/2017-12/2018 was randomly split into a training and test-set (3:1-ratio). Using a customized algorithm ("reference standard") loop gain was quantified from raw polysomnography signals on a continuous scale and additionally dichotomized (high > 0.7). Candidate predictors included general patient characteristics and routine polysomnography data. The model was developed (training-set) using linear regression with backward selection (tenfold cross-validated mean square errors); the predicted loop gain of the final linear regression model was used to predict loop gain class. More complex, alternative models including lasso regression or random forests were considered but did not meet pre-specified superiority-criteria. Final model performance was validated on the test-set.ResultsThe total cohort included 1055 patients (33% high loop gain). Based on the final model, higher AHI (beta = 0.0016; P
Published: 2022

94. Fine‐scale phenotypic variation of a large herbivore in a pulsed environment

Author: Aaron M. Foley, Kory Gann, David G. Hewitt, Randy W. DeYoung, Timothy E. Fulbright, J. Alfonso Ortega‐S., and Tyler A. Campbell
Subjects: phenotype variation, pulsed envrionments, resource rule hypothesis, white‐tailed deer, Ecology, QH540-549.5
Abstract: Abstract The resource rule hypothesis predicts that geographic differences in body size among populations of organisms are due to the amount, availability, and quality of food resources. For instance, the body size of large herbivores is often correlated with soil characteristics because better soils produce better forage. In semiarid environments, rainfall variation is an important driver of forage availability, especially highly nutritious annual forbs. Thus, in such pulsed‐resource environments, it is unclear whether the body size of large herbivores is influenced by fixed resources correlated with soil characteristics, irregular resource pulses correlated with rainfall, or both. Furthermore, it is not clear whether phenotypic expression is a function of forage quality or quantity. During the early autumns of 2011–2018, we captured 4554 white‐tailed deer (Odocoileus virginianus) on seven rangeland sites in the semiarid climate of South Texas, USA. The sites range from coastal to 140 km inland and represent gradients in both soil texture and annual rainfall. We recorded age‐ and sex‐specific indices of skeletal size, antler size, and body mass. Site‐specific soil characteristics explained most of the variation in skeletal size; percent sand was inversely related to skeletal size. For environmentally sensitive phenotypes (antler size and body mass), both soil characteristics and rainfall were influencers; increases in rainfall reduced the negative effect of sand. Percent sand and rainfall were positively correlated with annual biomass of preferred forbs, yet all phenotypic traits declined with increases in forb quantity. Increases in percent shrub cover increased all phenotype sizes. Our data suggest that the phenotypic expression of large herbivores in semiarid environments is driven by forage quality via edaphic characteristics rather than forage quantity via rainfall. Specifically, less sand in the soil allows for the development of shrub communities, which in turn provide a consistent source of forage in a variable, pulsed‐rainfall environment. Although forbs are of higher quality, they are highly ephemeral. The availability of a consistent source of forage may enable white‐tailed deer to extend time invested in body growth, which results in greater phenotype size. Our findings align with the resource rule hypothesis that identifies resource availability as a fundamental element explaining geographical variation in phenotypic expression.
Published: 2024
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95. Cervical collar use in spinal cord injury management

Author: Shruti Kolli, Robert Medina, Chloe DeYoung, and Brandon Lucke‐Wold
Subjects: cervical collars, cervical spinal injury, spinal cord injury, spinal immobilization, spinal motion restriction, spinal surgery, Therapeutics. Pharmacology, RM1-950
Abstract: Abstract Background The use of cervical collars in the management of acute cervical spine injuries has been part of standard practice in the trauma setting for decades, aimed at preventing secondary injuries. Objectives To review the recent evidence challenging the routine use of cervical collars, addressing the limited scientific support, associated risks, and guidelines for their use. Methods A comprehensive literature review was conducted, analyzing recent studies and guidelines from authoritative bodies such as the American Association for Neurological Surgeons and the Congress of Neurological Surgeons. The review focused on the efficacy, risks, and recommendations regarding cervical collar use in acute cervical spine injuries. Results Recent evidence questions the routine use of cervical collars, highlighting limited scientific support and several associated risks, including pressure ulcers and decreased venous return. Cervical collars may also be contraindicated in individuals with abnormal spinal structures, such as those with Ankylosing Spondylitis. The efficacy of cervical collars is debated, particularly concerning undiagnosed spinal fractures, where delayed diagnosis can result in permanent injuries. Despite these risks, cervical collars may be beneficial in low‐resource areas and when used effectively with early clearance post‐injury. Current guidelines recommend immobilizing patients suspected of cervical spine injury but stress the importance of proper evaluation of the need for immobilization. Recent guidelines advocate for spinal motion restriction over traditional immobilization, emphasizing the need for better risk assessment and implementation strategies. Conclusions/Clinical Importance Re‐evaluating the routine use of cervical collars is crucial due to potential risks and limited supporting evidence, with a focus on individualized assessment and adherence to updated guidelines favoring spinal motion restriction.
Published: 2024
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96. Evaluation of drone surveys for ungulates in southwestern rangelands

Author: Jesse Blum, Aaron M. Foley, Randy W. DeYoung, David G. Hewitt, Jeremy Baumgardt, Mickey W. Hellickson, and Humberto L. Perotto‐Baldivieso
Subjects: distance sampling, drones, Odocoileus virginianus, population estimation, thermal, UAS, General. Including nature conservation, geographical distribution, QH1-199.5
Abstract: Abstract Drone platforms are increasingly used for aerial wildlife surveys, but the validity of population counts has not been fully evaluated in all environments. Aerial surveys generally undercount the true population size and one must estimate detection probability (p) to correct for missed individuals. Detection probability for visual observers is influenced by vegetation and terrain characteristics, but the use of thermal cameras as the observer may also introduce additional factors influencing detection probability. We conducted diurnal, thermal‐based drone surveys for ungulates during February–April 2020 in South Texas, USA, on sites with varying degrees of woody cover and terrain. We examined histograms of georeferenced perpendicular distances to determine the effect of habitat on detection probabilities. We also examined precision in population estimates and variation in repeated surveys. Finally, we compared drone population estimates to independent estimates derived from helicopter, spotlight, and trail‐camera surveys. Distributions of perpendicular distances from the transect were affected by habitat characteristics. A flat grassland site had relatively few detections near the transect because thermal (solar) reflectance in the center of the footage obscured detections. A hilly brushy site had a uniform p (1.00) but resulted in a severe undercount due to the inability of the drone to follow contours of hills. The flat brushy site had a lower p (0.63), indicating visibility bias. Two additional flat, brushy sites were surveyed repeatedly (n = 5 and 9 surveys, respectively). All combinations of up to 3 repeated surveys were pooled to meet the recommended minimum number of detections for distance sampling analyses (≥60 detections). Population estimates had acceptable precision (CV ≤ 20%) 80.7% of the time and variation among repeated surveys was acceptable (CV = 9% and 23%, respectively). Drone‐based population estimates were comparable with estimates generated from corrected helicopter, spotlight, and trail‐camera surveys. Overall, diurnal drone surveys can generate population estimates for large ungulates on southwestern rangelands after accounting for visibility bias, but may be limited by terrain and thermal conditions.
Published: 2024
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97. Searches for Connections between Dark Matter and High-Energy Neutrinos with IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Hettinger, E. C., Heuermann, L., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mari{ş}, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguy{\~{ê}}n, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Sogaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract: In this work, we present the results of searches for signatures of dark matter decay or annihilation into Standard Model particles, and secret neutrino interactions with dark matter. Neutrinos could be produced in the decay or annihilation of galactic or extragalactic dark matter. Additionally, if an interaction between dark matter and neutrinos exists then dark matter will interact with extragalactic neutrinos. In particular galactic dark matter will induce an anisotropy in the neutrino sky if this interaction is present. We use seven and a half years of the High-Energy Starting Event (HESE) sample data, which measures neutrinos in the energy range of approximately 60 TeV to 10 PeV, to study these phenomena. This all-sky event selection is dominated by extragalactic neutrinos. For dark matter of $\sim$ 1 PeV in mass, we constrain the velocity-averaged annihilation cross section to be smaller than $10^{-23}$cm$^3$/s for the exclusive $\mu^+\mu^-$ channel and $10^{-22}$ cm$^3$/s for the $b\bar b$ channel. For the same mass, we constrain the lifetime of dark matter to be larger than $10^{28}$ s for all channels studied, except for decaying exclusively to $b\bar b$ where it is bounded to be larger than $10^{27}$ s. Finally, we also search for evidence of astrophysical neutrinos scattering on galactic dark matter in two scenarios. For fermionic dark matter with a vector mediator, we constrain the dimensionless coupling associated with this interaction to be less than 0.1 for dark matter mass of 0.1 GeV and a mediator mass of $10^{-4}~$ GeV. In the case of scalar dark matter with a fermionic mediator, we constrain the coupling to be less than 0.1 for dark matter and mediator masses below 1 MeV., Comment: 23 pages, 8 figures
Published: 2022

98. Searches for Neutrinos from Gamma-Ray Bursts using the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Hamdaoui, H., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Helbing, K., Hellrung, J., Henningsen, F., Hettinger, E. C., Heuermann, L., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kelley, J. L., Kheirandish, A., Kin, K., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Sainte, W. Marie, Mariş, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Merckx, Y., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., Osborn, J., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Sogaard, A., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Upshaw, K., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., Zhelnin, P., Goldstein, A., and Wood, J.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: Gamma-ray bursts (GRBs) are considered as promising sources of ultra-high-energy cosmic rays (UHECRs) due to their large power output. Observing a neutrino flux from GRBs would offer evidence that GRBs are hadronic accelerators of UHECRs. Previous IceCube analyses, which primarily focused on neutrinos arriving in temporal coincidence with the prompt gamma rays, found no significant neutrino excess. The four analyses presented in this paper extend the region of interest to 14 days before and after the prompt phase, including generic extended time windows and targeted precursor searches. GRBs were selected between May 2011 and October 2018 to align with the data set of candidate muon-neutrino events observed by IceCube. No evidence of correlation between neutrino events and GRBs was found in these analyses. Limits are set to constrain the contribution of the cosmic GRB population to the diffuse astrophysical neutrino flux observed by IceCube. Prompt neutrino emission from GRBs is limited to $\lesssim$1% of the observed diffuse neutrino flux, and emission on timescales up to $10^4$ s is constrained to 24% of the total diffuse flux.
Published: 2022
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99. Framework and Tools for the Simulation and Analysis of the Radio Emission from Air Showers at IceCube

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Boddenberg, M., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Connolly, A., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mariş, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thwaites, J., Tilav, S., Tischbein, F., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: Astrophysics - High Energy Astrophysical Phenomena
Abstract: The Surface Enhancement of the IceTop air-shower array will include the addition of radio antennas and scintillator panels, co-located with the existing ice-Cherenkov tanks and covering an area of about 1 km$^2$. Together, these will increase the sensitivity of the IceCube Neutrino Observatory to the electromagnetic and muonic components of cosmic-ray-induced air showers at the South Pole. The inclusion of the radio technique necessitates an expanded set of simulation and analysis tools to explore the radio-frequency emission from air showers in the 70 MHz to 350 MHz band. In this paper we describe the software modules that have been developed to work with time- and frequency-domain information within IceCube's existing software framework, IceTray, which is used by the entire IceCube collaboration. The software includes a method by which air-shower simulation, generated using CoREAS, can be reused via waveform interpolation, thus overcoming a significant computational hurdle in the field.
Published: 2022
Full Text: View/download PDF

100. First Search for Unstable Sterile Neutrinos with the IceCube Neutrino Observatory

Author: Abbasi, R., Ackermann, M., Adams, J., Aguilar, J. A., Ahlers, M., Ahrens, M., Alameddine, J. M., Alves Jr., A. A., Amin, N. M., Andeen, K., Anderson, T., Anton, G., Argüelles, C., Ashida, Y., Axani, S., Bai, X., V., A. Balagopal, Barwick, S. W., Bastian, B., Basu, V., Baur, S., Bay, R., Beatty, J. J., Becker, K. -H., Tjus, J. Becker, Beise, J., Bellenghi, C., Benda, S., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Binder, G., Bindig, D., Blaufuss, E., Blot, S., Boddenberg, M., Bontempo, F., Book, J. Y., Borowka, J., Böser, S., Botner, O., Böttcher, J., Bourbeau, E., Bradascio, F., Braun, J., Brinson, B., Bron, S., Brostean-Kaiser, J., Burley, R. T., Busse, R. S., Campana, M. A., Carnie-Bronca, E. G., Chen, C., Chen, Z., Chirkin, D., Choi, K., Clark, B. A., Clark, K., Classen, L., Coleman, A., Collin, G. H., Conrad, J. M., Coppin, P., Correa, P., Cowen, D. F., Cross, R., Dappen, C., Dave, P., De Clercq, C., DeLaunay, J. J., López, D. Delgado, Dembinski, H., Deoskar, K., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., de With, M., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dittmer, M., Dujmovic, H., Dunkman, M., DuVernois, M. A., Ehrhardt, T., Eller, P., Engel, R., Erpenbeck, H., Evans, J., Evenson, P. A., Fan, K. L., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Fienberg, A. T., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Friedman, E., Fritz, A., Fürst, P., Gaisser, T. K., Gallagher, J., Ganster, E., Garcia, A., Garrappa, S., Gerhardt, L., Ghadimi, A., Glaser, C., Glauch, T., Glüsenkamp, T., Goehlke, N., Gonzalez, J. G., Goswami, S., Grant, D., Grégoire, T., Griswold, S., Günther, C., Gutjahr, P., Haack, C., Hallgren, A., Halliday, R., Halve, L., Halzen, F., Minh, M. Ha, Hanson, K., Hardin, J., Harnisch, A. A., Haungs, A., Hebecker, D., Helbing, K., Henningsen, F., Hettinger, E. C., Hickford, S., Hignight, J., Hill, C., Hill, G. C., Hoffman, K. D., Hoshina, K., Hou, W., Huang, F., Huber, M., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., In, S., Iovine, N., Ishihara, A., Jansson, M., Japaridze, G. S., Jeong, M., Jin, M., Jones, B. J. P., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katz, U., Kauer, M., Kellermann, M., Kelley, J. L., Kheirandish, A., Kin, K., Kintscher, T., Kiryluk, J., Klein, S. R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Kopper, S., Koskinen, D. J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krupczak, E., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lanfranchi, J. L., Larson, M. J., Lauber, F., Lazar, J. P., Lee, J. W., Leonard, K., Leszczyńska, A., Li, Y., Lincetto, M., Liu, Q. R., Liubarska, M., Lohfink, E., Mariscal, C. J. Lozano, Lu, L., Lucarelli, F., Ludwig, A., Luszczak, W., Lyu, Y., Ma, W. Y., Madsen, J., Mahn, K. B. M., Makino, Y., Mancina, S., Mariş, I. C., Martinez-Soler, I., Maruyama, R., McCarthy, S., McElroy, T., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Meighen-Berger, S., Micallef, J., Mockler, D., Montaruli, T., Moore, R. W., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Naumann, U., Necker, J., Nguyen, L. V., Niederhausen, H., Nisa, M. U., Nowicki, S. C., Pollmann, A. Obertacke, Oehler, M., Oeyen, B., Olivas, A., O'Sullivan, E., Pandya, H., Pankova, D. V., Park, N., Parker, G. K., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Peters, L., Peterson, J., Philippen, S., Pieper, S., Pizzuto, A., Plum, M., Popovych, Y., Porcelli, A., Rodriguez, M. Prado, Pries, B., Przybylski, G. T., Raab, C., Rack-Helleis, J., Raissi, A., Rameez, M., Rawlins, K., Rea, I. C., Rechav, Z., Rehman, A., Reichherzer, P., Reimann, R., Renzi, G., Resconi, E., Reusch, S., Rhode, W., Richman, M., Riedel, B., Roberts, E. J., Robertson, S., Roellinghoff, G., Rongen, M., Rott, C., Ruhe, T., Ryckbosch, D., Cantu, D. Rysewyk, Safa, I., Saffer, J., Sampathkumar, P., Herrera, S. E. Sanchez, Sandrock, A., Santander, M., Sarkar, S., Satalecka, K., Schaufel, M., Schieler, H., Schindler, S., Schmidt, T., Schneider, A., Schneider, J., Schröder, F. G., Schumacher, L., Schwefer, G., Sclafani, S., Seckel, D., Seunarine, S., Sharma, A., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Soldin, D., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stein, R., Stettner, J., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Thwaites, J., Tilav, S., Tischbein, F., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Tselengidou, M., Tung, C. F., Turcati, A., Turcotte, R., Turley, C. F., Twagirayezu, J. P., Ty, B., Elorrieta, M. A. Unland, Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Veitch-Michaelis, J., Verpoest, S., Walck, C., Wang, W., Watson, T. B., Weaver, C., Weigel, P., Weindl, A., Weiss, M. J., Weldert, J., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Willey, N., Williams, D. R., Wolf, M., Wrede, G., Wulff, J., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Yu, S., Yuan, T., Zhang, Z., and Zhelnin, P.
Subjects: High Energy Physics - Experiment
Abstract: We present a search for an unstable sterile neutrino by looking for a matter-induced signal in eight years of atmospheric $\nu_\mu$ data collected from 2011 to 2019 at the IceCube Neutrino Observatory. Both the (stable) three-neutrino and the 3+1 sterile neutrino models are disfavored relative to the unstable sterile neutrino model, though with $p$-values of 2.5\% and 0.81\%, respectively, we do not observe evidence for 3+1 neutrinos with neutrino decay. The best-fit parameters for the sterile neutrino with decay model from this study are $\Delta m_{41}^2=6.7^{+3.9}_{-2.5}\,\rm{eV}^2$, $\sin^2 2\theta_{24}=0.33^{+0.20}_{-0.17}$, and $g^2=2.5\pi\pm1.5\pi$, where $g$ is the decay-mediating coupling. The preferred regions from short-baseline oscillation searches are excluded at 90\% C.L.
Published: 2022
Full Text: View/download PDF

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