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752 results on '"De Nicola S."'

54. Code design for radar STAP via optimization theory

Author

De Maio, A., De Nicola, S., Yongwei Huang Palomar, D.P. Shuzhong, and Zhang Farina, A.

Subjects
Gaussian processes -- Analysis, Mathematical optimization -- Usage, Radar systems -- Analysis, Signal processing -- Analysis, Waveforms -- Analysis, Digital signal processor, Business, Computers, Electronics, Electronics and electrical industries
Published
2010

56. Design of phase codes for radar performance optimization with a similarity constraint

Author

De Maio, A., De Nicola, S., Yongwei Huang, Zhi-Quan Luo, and Shuzhong Zhang

Subjects
Polynomials -- Usage, Radar systems -- Evaluation, Random noise theory -- Analysis, Signal processing -- Analysis, Waveforms -- Evaluation, Digital signal processor, Business, Computers, Electronics, Electronics and electrical industries
Published
2009

57. The optimal timing of hepatitis C therapy in liver transplant-eligible patients: Cost-effectiveness analysis of new opportunities

Author

Cortesi, P, Belli, L, Facchetti, R, Mazzarelli, C, Perricone, G, De Nicola, S, Cesana, G, Duvoux, C, Mantovani, L, Strazzabosco, M, Cortesi, P. A., Belli, L. S., Facchetti, R., Mazzarelli, C., Perricone, G., De Nicola, S., Cesana, G., Duvoux, C., Mantovani, L. G., Strazzabosco, M., Cortesi, P, Belli, L, Facchetti, R, Mazzarelli, C, Perricone, G, De Nicola, S, Cesana, G, Duvoux, C, Mantovani, L, Strazzabosco, M, Cortesi, P. A., Belli, L. S., Facchetti, R., Mazzarelli, C., Perricone, G., De Nicola, S., Cesana, G., Duvoux, C., Mantovani, L. G., and Strazzabosco, M.

Abstract

Different strategies of DAAs treatment are currently possible both pre- and postliver transplantation (LT). Clinical and economic consequences of these strategies still need to be adequately investigated; this study aims at assessing their cost-effectiveness. A decision analytical model was created to simulate the progression of HCV-infected patients listed for decompensated cirrhosis (DCC) or for hepatocellular carcinoma (HCC). Three DAAs treatment strategies were compared: (i) a 12-week course of DAAs prior to transplantation (PRE-LT), (ii) a 4-week course of DAAs starting at the time of transplantation (PERI-LT) and (iii) a 12-week course of DAAs administered at disease recurrence (POST-LT). The population was substratified according to HCC presence and, in those without HCC, according to the MELD score at listing. Data on DAAs effectiveness were estimated using a cohort of patients still followed by 11 transplant centres of the European Liver and Intestine Transplant Association and by data available in the literature. In this study, PRE-LT treatment strategy was dominant for DCC patients with MELD<16 and cost-effective for those with MELD16-20, while POST-LT strategy emerged as cost-effective for DCC patients with MELD>20 and for those with HCC. Sensitivity analyses confirmed PRE-LT as the cost-effective strategy for patients with MELD≤20. In conclusion, PRE-LT treatment is cost-effective for patients with MELD≤20 without HCC, while treatments after LT are cost-effective in cirrhotic patients with MELD>20 and in those with HCC. It is worth reminding, though, that the final choice of a specific regimen at the patient level will have to be personalized based on clinical, social and transplant-related factors

Published
2018

58. Nonlinearity at an Interface

Author

Bloisi, F., Vicari, L., De Nicola, S., Finizio, A., Mormile, P., Pierattini, G., Kaplan, A. E., Martellucci, S., Quartieri, J., Zichichi, Antonino, editor, Martellucci, S., editor, and Chester, A. N., editor

Published
1990
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65. Liver transplant recipients with Covid-19: results from an Italian multicenter cohort

Author

Mazzarelli, C., primary, Viganò, R., additional, Perricone, G., additional, Merli, M., additional, Pasulo, L., additional, Invernizzi, F., additional, Bhoori, S., additional, Morelli, M.C., additional, Patrono, D., additional, Sandro, S. Di, additional, Cortesi, P., additional, Angrisani, D., additional, De Nicola, S., additional, Vangeli, M., additional, and Belli, L.S., additional

Published
2021
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66. Liver transplant candidates and SARS-CoV-2 infection: Results from an Italian multicenter cohort

Author

Perricone, G., primary, Vigano, R., additional, Mazzarelli, C., additional, Travi, G., additional, Pasulo, L., additional, Invernizzi, F., additional, Morelli, M.C., additional, Patrono, D., additional, Sandro, S. Di, additional, De Simone, P., additional, Facchetti, R., additional, Angrisani, D., additional, De Nicola, S., additional, Airoldi, A., additional, Vangeli, M., additional, and Belli, e L.S., additional

Published
2021
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85. 03:18 PM Abstract No. 75 Portal cavernoma revascularization through splenic access in symptomatic portal hypertension: a paradigm shift in interventional radiology

Author

Rampoldi, A., primary, Barbosa, F., additional, Di Sandro, S., additional, Nichelatti, M., additional, De Gasperi, A., additional, De Nicola, S., additional, Vercelli, R., additional, Migliorisi, C., additional, Mazzarelli, C., additional, Solcia, M., additional, Airoldi, A., additional, Belli, L., additional, and De Carlis, L., additional

Published
2019
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87. Clinical presentation and etiological spectrum of idiopathic non-cirrhotic portal hypertension (INCPH): data from the Italian Registry

Author

Primignani, M., primary, Tosetti, G., additional, La Mura, V., additional, Bitto, N., additional, Turco, L., additional, Bianchini, M., additional, Gioia, S., additional, Maggioni, M., additional, Senzolo, M., additional, Ferrarese, A., additional, Angeli, P., additional, Colloredo, G., additional, Airoldi, A., additional, Angrisani, D., additional, De Nicola, S., additional, Sarcognato, S., additional, Lampertico, P., additional, Schepis, F., additional, Riggio, O., additional, and Guido, M., additional

Published
2019
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89. EuPRAXIA – a compact, cost-efficient particle and radiation source

Author

Weikum, M. K., primary, Akhter, T., additional, Alesini, P. D., additional, Alexandrova, A. S., additional, Anania, M. P., additional, Andreev, N. E., additional, Andriyash, I., additional, Aschikhin, A., additional, Assmann, R. W., additional, Audet, T., additional, Bacci, A., additional, Barna, I. F., additional, Beaton, A., additional, Beck, A., additional, Beluze, A., additional, Bernhard, A., additional, Bielawski, S., additional, Bisesto, F. G., additional, Brandi, F., additional, Bringer, O., additional, Brinkmann, R., additional, Bründermann, E., additional, Büscher, M., additional, Bussmann, M., additional, Bussolino, G. C., additional, Chance, A., additional, Chanteloup, J. C., additional, Chen, M., additional, Chiadroni, E., additional, Cianchi, A., additional, Clarke, J., additional, Cole, J., additional, Couprie, M. E., additional, Croia, M., additional, Cros, B., additional, Crump, P., additional, Dattoli, G., additional, Delerue, N., additional, Delferriere, O., additional, Delinikolas, P., additional, De Nicola, S., additional, Dias, J., additional, Dorda, U., additional, Fedele, R., additional, Pousa, A. Ferran, additional, Ferrario, M., additional, Filippi, F., additional, Fils, J., additional, Fiore, G., additional, Fonseca, R. A., additional, Galimberti, M., additional, Gallo, A., additional, Garzella, D., additional, Gastinel, P., additional, Giove, D., additional, Giribono, A., additional, Gizzi, L. A., additional, Grüner, F. J., additional, Habib, A. F., additional, Heinemann, T., additional, Hidding, B., additional, Holzer, B. J., additional, Hooker, S. M., additional, Hosokai, T., additional, Hübner, M., additional, Irman, A., additional, Jafarinia, F., additional, Jaroszynski, D. A., additional, Jaster-Merz, S., additional, Joshi, C., additional, Kaluza, M. C., additional, Kando, M., additional, Karger, O. S., additional, Karsch, S., additional, Khazanov, E., additional, Khikhlukha, D., additional, Knetsch, A., additional, Kocon, D., additional, Koester, P., additional, Kononenko, O., additional, Korn, G., additional, Kostyukov, I., additional, Kruchinin, K., additional, Labate, L., additional, Lechner, C., additional, Leemans, W. P., additional, Lehrach, A., additional, Li, F. Y., additional, Li, X., additional, Libov, V., additional, Lifschitz, A., additional, Litvinenko, V., additional, Lu, W., additional, Lundh, O., additional, Maier, A. R., additional, Malka, V., additional, Manahan, G. G., additional, Mangles, S. P. D., additional, Marchetti, B., additional, Marocchino, A., additional, de la Ossa, A. Martinez, additional, Martins, J. L., additional, Mason, P., additional, Massimo, F., additional, Mathieu, F., additional, Maynard, G., additional, Mazzotta, Z., additional, Mehrling, T. J., additional, Molodozhentsev, A. Y., additional, Mostacci, A., additional, Müller, A. S., additional, Murphy, C. D., additional, Najmudin, Z., additional, Nghiem, P. A. P., additional, Nguyen, F., additional, Niknejadi, P., additional, Osterhoff, J., additional, Papadopoulos, D., additional, Patrizi, B., additional, Petrillo, V., additional, Pocsai, M. A., additional, Poder, K., additional, Pompili, R., additional, Pribyl, L., additional, Pugacheva, D., additional, Romeo, S., additional, Rajeev, P. P., additional, Conti, M. Rossetti, additional, Rossi, A. R., additional, Rossmanith, R., additional, Roussel, E., additional, Sahai, A. A., additional, Sarri, G., additional, Schaper, L., additional, Scherkl, P., additional, Schramm, U., additional, Schroeder, C. B., additional, Schwindling, J., additional, Scifo, J., additional, Serafini, L., additional, Sheng, Z. M., additional, Silva, L. O., additional, Silva, T., additional, Simon, C., additional, Sinha, U., additional, Specka, A., additional, Streeter, M. J. V., additional, Svystun, E. N., additional, Symes, D., additional, Szwaj, C., additional, Tauscher, G., additional, Terzani, D., additional, Thompson, N., additional, Toci, G., additional, Tomassini, P., additional, Torres, R., additional, Ullmann, D., additional, Vaccarezza, C., additional, Vannini, M., additional, Vieira, J. M., additional, Villa, F., additional, Wahlström, C. -G., additional, Walczak, R., additional, Walker, P. A., additional, Wang, K., additional, Welsch, C. P., additional, Wolfenden, J., additional, Xia, G., additional, Yabashi, M., additional, Yu, L., additional, Zhu, J., additional, and Zigler, A., additional

Published
2019
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92. Fabrication and characterizations of films made of Te/TeO 2 nanopowder consolidated by poly(methyl methacrylate)

Author

Palomba, M., Coscia, U., Carotenuto, G., De Nicola, S., Ambrosone, G., Palomba, M, Coscia, Ubaldo, Carotenuto, Gianfranco, Nicola, S. De, and Ambrosone, Giuseppina

Subjects
Poly(methyl methacrylate), Materials science, Photoconductivity, Scanning electron microscope, chemistry.chemical_element, Vibration milling, Condensed Matter Physics, chemistry.chemical_compound, chemistry, Chemical engineering, visual_art, X-ray crystallography, visual_art.visual_art_medium, Tellurium, Methyl methacrylate, Thin film, Power density
Abstract

Tellurium based material was obtained by binding nanosized tellurium grains, produced by dry vibration milling technique, with poly(methyl methacrylate) (PMMA). The morphology, structural and electrical properties of Te/PMMA films were investigated. The photoelectrical properties of the films were studied under white light illumination varying the optical power density from 2 to 170mW/cm2 and turning on and off the light cyclically. In order to determine the effects of milling technique two sets of Te/PMMA samples were produced by binding the “as received” and milled Te powders with PMMA. A quite prompt and evident photoresponse was observed for the material prepared with Te nanopowder, while not significant variations of the conductivity were detected in a reference sample fabricated with the as received coarse Te powder and illuminated in the same optical power density range. The origin of the photoconduction can be attributed to the enhancement of the ratio between TeO2 and Te phases in the nanopowder occurring during the milling stage. (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

Published
2015
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95. Imidazole-stabilized gold nanoparticles induce neuronal apoptosis: An in vitro and in vivo study

Author

Imperatore, R, Carotenuto, G, Di Grazia MA, Ferrandino, I, Palomba, Letizia, Mariotti, R, Vitale, E, De Nicola, S, Longo, A, Cristino, L., Imperatore, R., Carotenuto, G., Di Grazia, Ma, Ferrandino, I., Palomba, L, Mariotti, R., Vitale, E., De Nicola, S., Longo, A., and Cristino, L.

Subjects
Neurons, Time Factors, Imidazoles, apoptosis, Brain, Metal Nanoparticles, blood brain barrier, cytotoxicity, neuroblastoma, thiolato ligands, Blood-brain barrier, Endocytosis, nanoparticelle, barriera emato encefalica, apoptosi, Mice, Inbred C57BL, tumore, Injections, Intravenous, In Situ Nick-End Labeling, Animals, Humans, Tissue Distribution, Gold, Cell Shape
Abstract

Gold nanoparticles are increasingly being employed in innovative biological applications thanks to their advantages of material- and size-dependent physics and chemical interactions with the cellular systems. On the other hand, growing concern has emerged on the toxicity which would render gold-based nanoparticles harmful to cell cultures, animals, and humans. Emerging attention is focused on the interaction of gold nanoparticles with nervous system, especially regarding the ability to overcome the blood-brain barrier (BBB) which represents the major impediment to the delivery of therapeutics into the brain. We synthesized highly stable 2-mercapto-1-methylimidazole-stabilized gold-nanoparticles (AuNPs)-mmi to investigate their entry, accumulation, and toxicity in vitro (SH-SY5Y human neuroblastoma cells) and in vivo (brain of C57BL/6 mice) through optical and electron microscopy. After incubation in the cell culture medium at the lowest dose of 0.1 mg/mL the (AuNPs)-mmi nanoparticles were found compacted and recruited into endosome/lysosomes (1 h) before their fusion (2 h) and the onset of neuronal death by apoptosis (4 h) as proved by terminal-transferase-mediated dUTP nick end labeling assay and caspase-3 immunoreactivity. The ability of (AuNPs)-mmi to cross the BBB was assessed by injection in the caudal vein of C57BL/6 mice. Among different brain regions, the nanoparticles were found in the CaudatoPutamen area, mainly in the striatal neurons 4 h after injection. These neurons showed the typical hallmarks of apoptosis. Our findings provide, for the first time, the dynamic of 2-mercapto-1-methylimidazole nanogold uptake. The molecular mechanism which underlies the nanogold-driven apoptotic event is analyzed and discussed in order to take into account when designing nanomaterials to interface with biological structures. © 2014 Wiley Periodicals, Inc.

Published
2015
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