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58. Hierarchical GNNs for Large Graph Generation

Author

Davies, Alex O., Ajmeri, Nirav S., and Filho, Telmo M. Silva

Subjects
Social and Information Networks (cs.SI), FOS: Computer and information sciences, Computer Science - Machine Learning, Artificial Intelligence (cs.AI), Computer Science - Artificial Intelligence, Computer Science - Social and Information Networks, Machine Learning (cs.LG)
Abstract

Large graphs are present in a variety of domains, including social networks, civil infrastructure, and the physical sciences to name a few. Graph generation is similarly widespread, with applications in drug discovery, network analysis and synthetic datasets among others. While GNN (Graph Neural Network) models have been applied in these domains their high in-memory costs restrict them to small graphs. Conversely less costly rule-based methods struggle to reproduce complex structures. We propose HIGGS (Hierarchical Generation of Graphs) as a model-agnostic framework of producing large graphs with realistic local structures. HIGGS uses GNN models with conditional generation capabilities to sample graphs in hierarchies of resolution. As a result HIGGS has the capacity to extend the scale of generated graphs from a given GNN model by quadratic order. As a demonstration we implement HIGGS using DiGress, a recent graph-diffusion model, including a novel edge-predictive-diffusion variant edge-DiGress. We use this implementation to generate categorically attributed graphs with tens of thousands of nodes. These HIGGS generated graphs are far larger than any previously produced using GNNs. Despite this jump in scale we demonstrate that the graphs produced by HIGGS are, on the local scale, more realistic than those from the rule-based model BTER., Comment: In submission for NeurIPS 23

Published
2023
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64. Multiple Small Bowel Intussusceptions in the Setting of Anabolic Steroid Use.

Author

Davies, Alex, Sangiorgio, Michael, and Patwardhan, Ashwin

Subjects
THROMBOEMBOLISM risk factors, SMALL intestine radiography, PATIENT aftercare, HOSPITAL emergency services, NAUSEA, PARASYMPATHOMIMETIC agents, CONSTIPATION, POLYCYTHEMIA, CHOLINESTERASE inhibitors, RISK assessment, URBAN hospitals, VOMITING, TREATMENT effectiveness, SMALL intestine, INTESTINAL intussusception, ANABOLIC steroids, COMPUTED tomography, ABDOMINAL pain, RARE diseases, ABDOMINAL radiography, DISCHARGE planning, DISEASE risk factors, ADULTS
Abstract

Adult intussusception is a rare phenomenon and often provides a unique diagnostic challenge, typically involving extensive investigation to rule out sinister pathology. We present the case of a healthy 28-year-old male, who presented with symptoms suggestive of small bowel obstruction. Computed tomography displayed evidence of a small bowel intussusception; however, thorough investigation was unremarkable, besides a marked polycythemia. The patient represented several months later with another bowel obstruction, at which time he disclosed the regular use of androgenous anabolic steroids (AAS), which are recognized to induce polycythemia. AAS increase the risk of thromboembolic events and have more recently been implicated as a risk factor for intussusception. This case aims to highlight the increasing prevalence of AAS use, and the importance of its consideration in diagnostic dilemmas, particularly in otherwise healthy adults presenting with intussusception. [ABSTRACT FROM AUTHOR]

Published
2024
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65. VIRGIL – Providing Institutional Access to a Repository of Access Grid Sessions

Author

Chernich, Ron, Hunter, Jane, Davies, Alex, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Kovács, László, editor, Fuhr, Norbert, editor, and Meghini, Carlo, editor

Published
2007
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66. Current Surgical Practice for Children Born with a Cleft lip and/or Palate in the United Kingdom.

Author

Fell, Matthew, Davies, Alex, Davies, Amy, Chummun, Shaheel, Cobb, Alistair R.M., Moar, Kanwalraj, and Wren, Yvonne

Subjects
PROFESSIONAL practice, CONFIDENCE intervals, CLEFT palate, PEDIATRICS, PLASTIC surgery, CLEFT lip, MEDICAL protocols, RESEARCH funding, DESCRIPTIVE statistics, ODDS ratio, LONGITUDINAL method
Abstract

Objective: This study describes primary surgical reconstructions performed for children born with a cleft lip and/or palate (CL ± P) in the United Kingdom (UK). Design: Data forms completed at the time of surgery included details on timing, technique, and adjuncts used during the operative period. Demographic data on participants were validated via parental questionnaires. Setting: Data were obtained from the Cleft Collective, a national longitudinal cohort study. Patients: Between 2015 and 2021, 1782 Cleft Collective surgical forms were included, relating to the primary reconstructions of 1514 individual children. Results: The median age at primary cheiloplasty was 4.3 months. Unilateral cleft lips (UCL) were reconstructed with an anatomical subunit approximation technique in 53%, whereas bilateral cleft lips (BCL) were reconstructed with a broader range of eponymous techniques. Clefts of the soft palate were reconstructed at a median age of 10.3 months with an intravelar veloplasty in 94% cases. Clefts of the hard palate were reconstructed with a vomer flap in 84% cases in a bimodal age distribution, relating to reconstruction carried out simultaneously with either lip or soft palate reconstruction. Antibiotics were used in 96% of cases, with an at-induction-only regimen used more commonly for cheiloplasties (P <.001) and a 5 to 7-day postoperative regime used more commonly for soft palatoplasties (P <.001). Perioperative steroids were used more commonly in palatoplasties than cheiloplasties (P <.001) but tranexamic acid use was equivalent (P =.73). Conclusions: This study contributes to our understanding of current cleft surgical pathways in the UK and will provide a baseline for analysis of the effectiveness of utilized protocols. [ABSTRACT FROM AUTHOR]

Published
2023
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68. Metasemantic Moral Encroachment

Author

Davies, Alex

Abstract

This is an experiment designed to check for evidence that the moral consequences of using a word with a given context in a given context affect the content of the word in the context.

Published
2022
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69. Cayman Islands - Trina Solar: A Warning Regarding Reliance on Merger Price and Deficient Disclosure in s238 Proceedings.

Author

Bodden, Erik, Davies, Alex, and Da Rocha, Mauricio

Subjects
PRICES, MERGERS & acquisitions, DISCOUNTED cash flow, MARKET prices, FAIR value
Abstract

The article discusses the Trina Solar case in the Cayman Islands, where dissenting shareholders sought fair value appraisal of their shares after a take-private transaction. The initial valuation relied on a combination of market price, transaction price, and discounted cash flow analysis. However, the Court of Appeal highlighted the challenges of relying solely on the merger price and emphasized the importance of robust disclosure and protections for shareholders. The Court increased the weight assigned to discounted cash flow analysis, resulting in dissenting shareholders receiving an uplift to the merger price. The ruling underscores the need for an independent special committee and adequate disclosure in similar proceedings. [Extracted from the article]

Published
2023

71. Extra Terrestrial

Author

Davies, Alex

Subjects
Carbon taxes, Railroads -- Environmental aspects -- Services -- Taxation, Global temperature changes, Climate change, Air travel, Forest fires, Computers, Hobbies and crafts, Sociology and social work
Abstract

Byline: BY Alex Davies ILLUSTRATION BY Alvaro Dominguez Extra Terrestrial Some environmentally conscious people are trying to give up flying. For many trips, there's a great, cleaner alternative: It's called [...]

Published
2020

72. Large-scale migration into Britain during the Middle to Late Bronze Age

Author

European Research Council, Croatian Science Foundation, Ministry of Culture (Czech Republic), Academy of Sciences of the Czech Republic, Leverhulme Trust, Culture Vannin, Hungarian Academy of Sciences, National Research, Development and Innovation Office (Hungary), Ministerio de Ciencia e Innovación (España), National Institutes of Health (US), John Templeton Foundation, Paul G. Allen Family Foundation, Howard Hughes Medical Institute, Patterson, Nick, Isakov, Michael, Booth, Thomas, Büster, Lindsey, Fischer, Claire-Elise, Olalde, Iñigo, Ringbauer, Harald, Akbari, Ali, Cheronet, Olivia, Bleasdale, Madeleine, Adamski, Nicole, Šefčáková, Alena, Curtis, Elizabeth, Sheridan, Alison, Glenis Tavarez Maria, Terry, Rachel, Teržan, Biba, Teschler-Nicola, Maria, Brunning, Richard, Torres-Martínez, Jesús F., Lawson, Ann Marie, Fowler, Chris, Trapp, Julien, Turle, Ross, Ujvári, Ferenc, van der Heiden, Menno, González Morales, Manuel R., Carlson, Kellie Sara Duffett, Veleminsky, Petr, Veselka, Barbara, Vytlačil, Zdeněk, Budd, Chelsea, Fox, Allison, Carnicero-Cáceres, Silvia, Waddington, Clive, Ware, Paula, Wilkinson, Paul, Wilson, Linda, Wiseman, Rob, Young, Eilidh, González-Rabanal, Borja, Zaninović, Joško, Edwards, Ceiridwen J, Gallina, Zsolt, Žitňan, Andrej, McSweeney, Kathleen, Burmaz, Josip, Lalueza-Fox, Carles, de Knijff, Peter, Barnes, Ian, Halkon, Peter, Thomas, Mark G, Kennett, Douglas J., Cunliffe, Barry, Hernu, Bénédicte, Green, Adrian, Lillie, Malcolm, Lazaridis, Iosif, Rohland, Nadin, Canet, Sylvain, Fernandes, Daniel M, Mah, Matthew, Mallick, Swapan, Mandl, Kirsten, Micco, Adam, Hey, Gill, Michel, Megan, Morante, Guillermo Bravo, Oppenheimer, Jonas, Özdoğan, Kadir Toykan, Habermehl, Diederick, Meijlink, Bernard, Harris, James, Qiu, Lijun, Schattke, Constanze, Stewardson, Kristin, Horňák, Milan, Workman, J Noah, Zalzala, Fatma, Zhang, Zhao, Agustí, Bibiana, Allen, Tim, Almássy, Katalin, Mende, Balazs G., Amkreutz, Luc, Skae, Sabine, Hajdu, Tamás, Ilon, Gábor, Ash, Abigail, Baillif-Ducros, Christèle, Barclay, Alistair, Bartosiewicz, László, Baxter, Katherine, Bernert, Zsolt, Blažek, Jan, Menđušić, Marko, Bodružić, Mario, Boissinot, Philippe, Stephens, Mark, Čaušević-Bully, Morana, Bonsall, Clive, Hamilton, Derek, Bradley, Pippa, Chamberlain, Andrew, Chauvin, Sébastien, Clough, Sharon, Čondić, Natalija, Metlička, Milan, Coppa, Alfredo, Istvánovits, Eszter, Craig, Oliver, Črešnar, Matija, Cummings, Vicki, Czifra, Szabolcs, Šmolíková, Miroslava, Hayden, Chris, Danielisová, Alžběta, Daniels, Robin, Davies, Alex, Meyer, Sophie, Milasinovic, Lidija, de Jersey, Philip, Deacon, Jody, Deminger, Csilla, Ditchfield, Peter W, Dizdar, Marko, Dobeš, Miroslav, Somogyi, Krisztina, Dobisíková, Miluše, Altena, Eveline, Domboróczki, László, Pinhasi, Ron, Mihovilić, Kristina, Drinkall, Gail, Đukić, Ana, Ernée, Michal, Evans, Christopher, Evans, Jane, Fernández-Götz, Manuel, Filipović, Slavica, Somogyvári, Ágnes, Fitzpatrick, Andrew, Jones, Andy M, Fokkens, Harry, Callan, Kimberly, Hendriks, Joep, Kavur, Martina Blečić, Kazek, Kevin, Kenyon, Robert A, Bernardos, Rebecca, Khreisheh, Amal, Kiss, Viktória, Kleijne, Jos, Knight, Mark, Szabó, Géza, Armit, Ian, Tabor, Jonathan, Kootker, Lisette M, Kovács, Péter F, Kozubová, Anita, Kulcsár, Gabriella, Kulcsár, Valéria, Le Pennec, Christophe, Brace, Selina, Legge, Michael, Leivers, Matt, Reich, David, Loe, Louise, Brittain, Marcus, Szécsényi-Nagy, Anna, López-Costas, Olalla, Lord, Tom, Los, Dženi, Lyall, James, Marín-Arroyo, Ana B., Mason, Philip, Matošević, Damir, Foody, M George B, Broomandkhoshbacht, Nasreen, Maxted, Andy, Minnitt, Steve, McIntyre, Lauren, Szeniczey, Tamás, McKinley, Jacqueline, Moore, Joanna, Morley, Geoff, Mullan, Graham, Musilová, Margaréta, Freilich, Suzanne, Neil, Benjamin, Nicholls, Rebecca, Novak, Mario, Pala, Maria, Candilio, Francesca, Brookes, Alison, Demetz, Lea, Papworth, Martin, Paresys, Cécile, Patten, Ricky, Goodchild, Helen, Perkić, Domagoj, Pesti, Krisztina, Petit, Alba, Petriščáková, Katarína, Pichon, Coline, Pickard, Catriona, Brown, Fraser, Pilling, Zoltán, Gamble, Michelle, Culleton, Brendan, Kearns, Aisling, Price, T. Douglas, Radović, Siniša, Redfern, Rebecca, Resutík, Branislav, Rhodes, Daniel T, Richards, Martin B, Roberts, Amy, Brown, Lisa, Roefstra, Jean, Sankot, Pavel, Gyenesei, Katalin, Tankó, Károly, European Research Council, Croatian Science Foundation, Ministry of Culture (Czech Republic), Academy of Sciences of the Czech Republic, Leverhulme Trust, Culture Vannin, Hungarian Academy of Sciences, National Research, Development and Innovation Office (Hungary), Ministerio de Ciencia e Innovación (España), National Institutes of Health (US), John Templeton Foundation, Paul G. Allen Family Foundation, Howard Hughes Medical Institute, Patterson, Nick, Isakov, Michael, Booth, Thomas, Büster, Lindsey, Fischer, Claire-Elise, Olalde, Iñigo, Ringbauer, Harald, Akbari, Ali, Cheronet, Olivia, Bleasdale, Madeleine, Adamski, Nicole, Šefčáková, Alena, Curtis, Elizabeth, Sheridan, Alison, Glenis Tavarez Maria, Terry, Rachel, Teržan, Biba, Teschler-Nicola, Maria, Brunning, Richard, Torres-Martínez, Jesús F., Lawson, Ann Marie, Fowler, Chris, Trapp, Julien, Turle, Ross, Ujvári, Ferenc, van der Heiden, Menno, González Morales, Manuel R., Carlson, Kellie Sara Duffett, Veleminsky, Petr, Veselka, Barbara, Vytlačil, Zdeněk, Budd, Chelsea, Fox, Allison, Carnicero-Cáceres, Silvia, Waddington, Clive, Ware, Paula, Wilkinson, Paul, Wilson, Linda, Wiseman, Rob, Young, Eilidh, González-Rabanal, Borja, Zaninović, Joško, Edwards, Ceiridwen J, Gallina, Zsolt, Žitňan, Andrej, McSweeney, Kathleen, Burmaz, Josip, Lalueza-Fox, Carles, de Knijff, Peter, Barnes, Ian, Halkon, Peter, Thomas, Mark G, Kennett, Douglas J., Cunliffe, Barry, Hernu, Bénédicte, Green, Adrian, Lillie, Malcolm, Lazaridis, Iosif, Rohland, Nadin, Canet, Sylvain, Fernandes, Daniel M, Mah, Matthew, Mallick, Swapan, Mandl, Kirsten, Micco, Adam, Hey, Gill, Michel, Megan, Morante, Guillermo Bravo, Oppenheimer, Jonas, Özdoğan, Kadir Toykan, Habermehl, Diederick, Meijlink, Bernard, Harris, James, Qiu, Lijun, Schattke, Constanze, Stewardson, Kristin, Horňák, Milan, Workman, J Noah, Zalzala, Fatma, Zhang, Zhao, Agustí, Bibiana, Allen, Tim, Almássy, Katalin, Mende, Balazs G., Amkreutz, Luc, Skae, Sabine, Hajdu, Tamás, Ilon, Gábor, Ash, Abigail, Baillif-Ducros, Christèle, Barclay, Alistair, Bartosiewicz, László, Baxter, Katherine, Bernert, Zsolt, Blažek, Jan, Menđušić, Marko, Bodružić, Mario, Boissinot, Philippe, Stephens, Mark, Čaušević-Bully, Morana, Bonsall, Clive, Hamilton, Derek, Bradley, Pippa, Chamberlain, Andrew, Chauvin, Sébastien, Clough, Sharon, Čondić, Natalija, Metlička, Milan, Coppa, Alfredo, Istvánovits, Eszter, Craig, Oliver, Črešnar, Matija, Cummings, Vicki, Czifra, Szabolcs, Šmolíková, Miroslava, Hayden, Chris, Danielisová, Alžběta, Daniels, Robin, Davies, Alex, Meyer, Sophie, Milasinovic, Lidija, de Jersey, Philip, Deacon, Jody, Deminger, Csilla, Ditchfield, Peter W, Dizdar, Marko, Dobeš, Miroslav, Somogyi, Krisztina, Dobisíková, Miluše, Altena, Eveline, Domboróczki, László, Pinhasi, Ron, Mihovilić, Kristina, Drinkall, Gail, Đukić, Ana, Ernée, Michal, Evans, Christopher, Evans, Jane, Fernández-Götz, Manuel, Filipović, Slavica, Somogyvári, Ágnes, Fitzpatrick, Andrew, Jones, Andy M, Fokkens, Harry, Callan, Kimberly, Hendriks, Joep, Kavur, Martina Blečić, Kazek, Kevin, Kenyon, Robert A, Bernardos, Rebecca, Khreisheh, Amal, Kiss, Viktória, Kleijne, Jos, Knight, Mark, Szabó, Géza, Armit, Ian, Tabor, Jonathan, Kootker, Lisette M, Kovács, Péter F, Kozubová, Anita, Kulcsár, Gabriella, Kulcsár, Valéria, Le Pennec, Christophe, Brace, Selina, Legge, Michael, Leivers, Matt, Reich, David, Loe, Louise, Brittain, Marcus, Szécsényi-Nagy, Anna, López-Costas, Olalla, Lord, Tom, Los, Dženi, Lyall, James, Marín-Arroyo, Ana B., Mason, Philip, Matošević, Damir, Foody, M George B, Broomandkhoshbacht, Nasreen, Maxted, Andy, Minnitt, Steve, McIntyre, Lauren, Szeniczey, Tamás, McKinley, Jacqueline, Moore, Joanna, Morley, Geoff, Mullan, Graham, Musilová, Margaréta, Freilich, Suzanne, Neil, Benjamin, Nicholls, Rebecca, Novak, Mario, Pala, Maria, Candilio, Francesca, Brookes, Alison, Demetz, Lea, Papworth, Martin, Paresys, Cécile, Patten, Ricky, Goodchild, Helen, Perkić, Domagoj, Pesti, Krisztina, Petit, Alba, Petriščáková, Katarína, Pichon, Coline, Pickard, Catriona, Brown, Fraser, Pilling, Zoltán, Gamble, Michelle, Culleton, Brendan, Kearns, Aisling, Price, T. Douglas, Radović, Siniša, Redfern, Rebecca, Resutík, Branislav, Rhodes, Daniel T, Richards, Martin B, Roberts, Amy, Brown, Lisa, Roefstra, Jean, Sankot, Pavel, Gyenesei, Katalin, and Tankó, Károly

Abstract

Present-day people from England and Wales have more ancestry derived from early European farmers (EEF) than did people of the Early Bronze Age1. To understand this, here we generated genome-wide data from 793 individuals, increasing data from the Middle to the Late Bronze Age and Iron Age in Britain by 12-fold, and western and central Europe by 3.5-fold. Between 1000 and 875 BC, EEF ancestry increased in southern Britain (England and Wales) but not northern Britain (Scotland) due to incorporation of migrants who arrived at this time and over previous centuries, and who were genetically most similar to ancient individuals from France. These migrants contributed about half the ancestry of people of England and Wales from the Iron Age, thereby creating a plausible vector for the spread of early Celtic languages into Britain. These patterns are part of a broader trend of EEF ancestry becoming more similar across central and western Europe in the Middle to the Late Bronze Age, coincident with archaeological evidence of intensified cultural exchange2-6. There was comparatively less gene flow from continental Europe during the Iron Age, and the independent genetic trajectory in Britain is also reflected in the rise of the allele conferring lactase persistence to approximately 50% by this time compared to approximately 7% in central Europe where it rose rapidly in frequency only a millennium later. This suggests that dairy products were used in qualitatively different ways in Britain and in central Europe over this period.

Published
2022

76. sj-docx-1-cpc-10.1177_10556656221078151 - Supplemental material for Current Surgical Practice for Children Born with a Cleft lip and/or Palate in the United Kingdom

Author

Fell, Matthew, Davies, Alex, Davies, Amy, Chummun, Shaheel, Cobb, Alistair R.M., Moar, Kanwalraj, and Wren, Yvonne

Subjects
FOS: Clinical medicine, 110323 Surgery
Abstract

Supplemental material, sj-docx-1-cpc-10.1177_10556656221078151 for Current Surgical Practice for Children Born with a Cleft lip and/or Palate in the United Kingdom by Matthew Fell, Alex Davies, Amy Davies, Shaheel Chummun, Alistair R.M. Cobb, Kanwalraj Moar and Yvonne Wren in The Cleft Palate-Craniofacial Journal

Published
2022
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79. Large-scale migration into Britain during the Middle to Late Bronze Age

Author

Patterson, Nick, primary, Isakov, Michael, additional, Booth, Thomas, additional, Büster, Lindsey, additional, Fischer, Claire-Elise, additional, Olalde, Iñigo, additional, Ringbauer, Harald, additional, Akbari, Ali, additional, Cheronet, Olivia, additional, Bleasdale, Madeleine, additional, Adamski, Nicole, additional, Altena, Eveline, additional, Bernardos, Rebecca, additional, Brace, Selina, additional, Broomandkhoshbacht, Nasreen, additional, Callan, Kimberly, additional, Candilio, Francesca, additional, Culleton, Brendan, additional, Curtis, Elizabeth, additional, Demetz, Lea, additional, Carlson, Kellie Sara Duffett, additional, Edwards, Ceiridwen J., additional, Fernandes, Daniel M., additional, Foody, M. George B., additional, Freilich, Suzanne, additional, Goodchild, Helen, additional, Kearns, Aisling, additional, Lawson, Ann Marie, additional, Lazaridis, Iosif, additional, Mah, Matthew, additional, Mallick, Swapan, additional, Mandl, Kirsten, additional, Micco, Adam, additional, Michel, Megan, additional, Morante, Guillermo Bravo, additional, Oppenheimer, Jonas, additional, Özdoğan, Kadir Toykan, additional, Qiu, Lijun, additional, Schattke, Constanze, additional, Stewardson, Kristin, additional, Workman, J. Noah, additional, Zalzala, Fatma, additional, Zhang, Zhao, additional, Agustí, Bibiana, additional, Allen, Tim, additional, Almássy, Katalin, additional, Amkreutz, Luc, additional, Ash, Abigail, additional, Baillif-Ducros, Christèle, additional, Barclay, Alistair, additional, Bartosiewicz, László, additional, Baxter, Katherine, additional, Bernert, Zsolt, additional, Blažek, Jan, additional, Bodružić, Mario, additional, Boissinot, Philippe, additional, Bonsall, Clive, additional, Bradley, Pippa, additional, Brittain, Marcus, additional, Brookes, Alison, additional, Brown, Fraser, additional, Brown, Lisa, additional, Brunning, Richard, additional, Budd, Chelsea, additional, Burmaz, Josip, additional, Canet, Sylvain, additional, Carnicero-Cáceres, Silvia, additional, Čaušević-Bully, Morana, additional, Chamberlain, Andrew, additional, Chauvin, Sébastien, additional, Clough, Sharon, additional, Čondić, Natalija, additional, Coppa, Alfredo, additional, Craig, Oliver, additional, Črešnar, Matija, additional, Cummings, Vicki, additional, Czifra, Szabolcs, additional, Danielisová, Alžběta, additional, Daniels, Robin, additional, Davies, Alex, additional, de Jersey, Philip, additional, Deacon, Jody, additional, Deminger, Csilla, additional, Ditchfield, Peter W., additional, Dizdar, Marko, additional, Dobeš, Miroslav, additional, Dobisíková, Miluše, additional, Domboróczki, László, additional, Drinkall, Gail, additional, Đukić, Ana, additional, Ernée, Michal, additional, Evans, Christopher, additional, Evans, Jane, additional, Fernández-Götz, Manuel, additional, Filipović, Slavica, additional, Fitzpatrick, Andrew, additional, Fokkens, Harry, additional, Fowler, Chris, additional, Fox, Allison, additional, Gallina, Zsolt, additional, Gamble, Michelle, additional, González Morales, Manuel R., additional, González-Rabanal, Borja, additional, Green, Adrian, additional, Gyenesei, Katalin, additional, Habermehl, Diederick, additional, Hajdu, Tamás, additional, Hamilton, Derek, additional, Harris, James, additional, Hayden, Chris, additional, Hendriks, Joep, additional, Hernu, Bénédicte, additional, Hey, Gill, additional, Horňák, Milan, additional, Ilon, Gábor, additional, Istvánovits, Eszter, additional, Jones, Andy M., additional, Kavur, Martina Blečić, additional, Kazek, Kevin, additional, Kenyon, Robert A., additional, Khreisheh, Amal, additional, Kiss, Viktória, additional, Kleijne, Jos, additional, Knight, Mark, additional, Kootker, Lisette M., additional, Kovács, Péter F., additional, Kozubová, Anita, additional, Kulcsár, Gabriella, additional, Kulcsár, Valéria, additional, Le Pennec, Christophe, additional, Legge, Michael, additional, Leivers, Matt, additional, Loe, Louise, additional, López-Costas, Olalla, additional, Lord, Tom, additional, Los, Dženi, additional, Lyall, James, additional, Marín-Arroyo, Ana B., additional, Mason, Philip, additional, Matošević, Damir, additional, Maxted, Andy, additional, McIntyre, Lauren, additional, McKinley, Jacqueline, additional, McSweeney, Kathleen, additional, Meijlink, Bernard, additional, Mende, Balázs G., additional, Menđušić, Marko, additional, Metlička, Milan, additional, Meyer, Sophie, additional, Mihovilić, Kristina, additional, Milasinovic, Lidija, additional, Minnitt, Steve, additional, Moore, Joanna, additional, Morley, Geoff, additional, Mullan, Graham, additional, Musilová, Margaréta, additional, Neil, Benjamin, additional, Nicholls, Rebecca, additional, Novak, Mario, additional, Pala, Maria, additional, Papworth, Martin, additional, Paresys, Cécile, additional, Patten, Ricky, additional, Perkić, Domagoj, additional, Pesti, Krisztina, additional, Petit, Alba, additional, Petriščáková, Katarína, additional, Pichon, Coline, additional, Pickard, Catriona, additional, Pilling, Zoltán, additional, Price, T. Douglas, additional, Radović, Siniša, additional, Redfern, Rebecca, additional, Resutík, Branislav, additional, Rhodes, Daniel T., additional, Richards, Martin B., additional, Roberts, Amy, additional, Roefstra, Jean, additional, Sankot, Pavel, additional, Šefčáková, Alena, additional, Sheridan, Alison, additional, Skae, Sabine, additional, Šmolíková, Miroslava, additional, Somogyi, Krisztina, additional, Somogyvári, Ágnes, additional, Stephens, Mark, additional, Szabó, Géza, additional, Szécsényi-Nagy, Anna, additional, Szeniczey, Tamás, additional, Tabor, Jonathan, additional, Tankó, Károly, additional, Maria, Clenis Tavarez, additional, Terry, Rachel, additional, Teržan, Biba, additional, Teschler-Nicola, Maria, additional, Torres-Martínez, Jesús F., additional, Trapp, Julien, additional, Turle, Ross, additional, Ujvári, Ferenc, additional, van der Heiden, Menno, additional, Veleminsky, Petr, additional, Veselka, Barbara, additional, Vytlačil, Zdeněk, additional, Waddington, Clive, additional, Ware, Paula, additional, Wilkinson, Paul, additional, Wilson, Linda, additional, Wiseman, Rob, additional, Young, Eilidh, additional, Zaninović, Joško, additional, Žitňan, Andrej, additional, Lalueza-Fox, Carles, additional, de Knijff, Peter, additional, Barnes, Ian, additional, Halkon, Peter, additional, Thomas, Mark G., additional, Kennett, Douglas J., additional, Cunliffe, Barry, additional, Lillie, Malcolm, additional, Rohland, Nadin, additional, Pinhasi, Ron, additional, Armit, Ian, additional, and Reich, David, additional

Published
2021
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80. Science Communication, Cultural Cognition, and the Pull of Epistemic Paternalism.

Author

Davies, Alex

Subjects
*SCIENTIFIC communication, *DELIBERATIVE democracy, *COGNITION, *PATERNALISM, *PHILOSOPHERS
Abstract

There is a correlation between positions taken on some scientific questions and political leaning. One way to explain this correlation is the cultural cognition hypothesis (CCH): people's political leanings are causing them to process evidence to maintain fixed answers to the questions, rather than to seek the truth. Another way is the different background belief hypothesis (DBBH): people of different political leanings have different background beliefs which rationalize different positions on these scientific questions. In this article, I argue for two things. I argue that two attempts by proponents of the CCH to discredit the DBBH fail. And I argue that this matters, because while the CCH makes epistemic paternalistic interventions seem called for (as some philosophers have argued compellingly), the DBBH does not. The DBBH makes it much easier to stay closer to an ideal of deliberative democracy. [ABSTRACT FROM AUTHOR]

Published
2023
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81. Syndromes associated with Robin sequence: a national prospective cohort study.

Author

Davies, Alex, Davies, Amy, Wren, Yvonne, Deacon, Scott, Cobb, Alistair, McLean, Neil, David, David, and Chummun, Shaheel

Subjects
COHORT analysis, LONGITUDINAL method, CLEFT palate, SYNDROMES, DIAGNOSTIC errors
Abstract

Objectives: To determine the prevalence of syndromic Robin sequence (RS) in the UK and if this group of patients had an increased need for airway and feeding management compared with a non-syndromic RS cohort.Design: A prospective national multicentre study of cases submitted to the Cleft Collective cohort studies.Setting: Specialist cleft services in the UK.Patients: 259 participants who fulfilled the diagnosis of RS. This group was compared with 548 participants with cleft palate only (CPO).Main Outcome Measures: The primary outcome measure was the presence of a syndrome in patients with RS and CPO. Secondary outcome measures included the use of airway and feeding adjuncts.Results: An associated syndrome was seen in 28% of patients with RS and 14% of patients with CPO. The most common syndrome for the RS group was Stickler syndrome (27%). Syndromic status was significantly higher among patients with RS compared with those with CPO (OR 2.36, 95% CI 1.65 to 3.39; p<0.001). Patients with syndromic RS have an increased reliance on airway adjuncts compared with the patients without syndromic RS (OR 2.02, 95% CI 1.13 to 3.64; p=0.018). There was no evidence of a difference in the use of feeding adjuncts between syndromic and non-syndromic RS groups (OR 2.43, 95% CI 0.78 to 7.58; p=0.126).Conclusion: The presence of a syndrome has implications for management of patients with RS. Early identification of a syndrome may help prevent the consequences of a missed syndromic diagnosis. Routine ophthalmological and genetic screening for Stickler syndrome should be mandatory for all patients with RS. [ABSTRACT FROM AUTHOR]

Published
2023
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85. Speed Kills-The Planet

Author

Davies, Alex

Subjects
Transportation industry -- Environmental aspects, Climate change -- Environmental aspects, Air pollution control -- Analysis, High speed trains, Aircraft, Computers, Hobbies and crafts, Sociology and social work
Abstract

Byline: -Alex Davies Speed Kills-the Planet The climate crisis is rushing at us like a bullet train. It's time to forget about velocity and focus on efficiency. psdJustin Fantl36 History [...]

Published
2019

86. Are We There Yet?

Author

Davies, Alex and Marshall, Aarian

Subjects
Driverless cars -- Innovations -- Analysis, Autonomous vehicles -- Innovations -- Analysis, Technology, Computers, Hobbies and crafts, Sociology and social work
Abstract

Byline: ALEX DAVIES AND AARIAN MARSHALL ILLUSTRATIONS BY Violet Reed ARE WE THERE YET? Fully autonomous cars may never arrive. But we'll all benefit from self-driving tech while we wait. [...]

Published
2019

87. Where We're Going

Author

Davies, Alex

Subjects
Flying automobiles -- Design and construction -- Innovations, Autonomous vehicles -- Design and construction -- Innovations, Algorithms, Data collection, Public transportation, Computers, Hobbies and crafts, Sociology and social work
Abstract

Byline: BY Alex Davies PHOTOGRAPH BY Christie Hemm Klok WHERE WE'RE GOING We've come a long way, but we are still cursing the traffic. It's true: We still need better [...]

Published
2019

91. Large-scale migration into Britain during the Middle to Late Bronze Age

Author

Patterson, Nick, Isakov, Michael, Booth, Thomas, Büster, Lindsey, Fischer, Claire-Elise, Olalde, Iñigo, Ringbauer, Harald, Akbari, Ali, Cheronet, Olivia, Bleasdale, Madeleine, Adamski, Nicole, Altena, Eveline, Bernardos, Rebecca, Brace, Selina, Broomandkhoshbacht, Nasreen, Callan, Kimberly, Candilio, Francesca, Culleton, Brendan, Curtis, Elizabeth, Demetz, Lea, Carlson, Kellie Sara Duffett, Fernandes, Daniel M, Foody, M George B, Freilich, Suzanne, Goodchild, Helen, Kearns, Aisling, Lawson, Ann Marie, Lazaridis, Iosif, Mah, Matthew, Mallick, Swapan, Mandl, Kirsten, Micco, Adam, Michel, Megan, Morante, Guillermo Bravo, Oppenheimer, Jonas, Özdoğan, Kadir Toykan, Qiu, Lijun, Schattke, Constanze, Stewardson, Kristin, Workman, J Noah, Zalzala, Fatma, Zhang, Zhao, Agustí, Bibiana, Allen, Tim, Almássy, Katalin, Amkreutz, Luc, Ash, Abigail, Baillif-Ducros, Christèle, Barclay, Alistair, Bartosiewicz, László, Baxter, Katherine, Bernert, Zsolt, Blažek, Jan, Bodružić, Mario, Boissinot, Philippe, Bonsall, Clive, Bradley, Pippa, Brittain, Marcus, Brookes, Alison, Brown, Fraser, Brown, Lisa, Brunning, Richard, Budd, Chelsea, Burmaz, Josip, Canet, Sylvain, Carnicero-Cáceres, Silvia, Čaušević-Bully, Morana, Chamberlain, Andrew, Chauvin, Sébastien, Clough, Sharon, Čondić, Natalija, Coppa, Alfredo, Craig, Oliver, Črešnar, Matija, Cummings, Vicki, Czifra, Szabolcs, Danielisová, Alžběta, Daniels, Robin, Davies, Alex, de Jersey, Philip, Deacon, Jody, Deminger, Csilla, Ditchfield, Peter W, Dizdar, Marko, Dobeš, Miroslav, Dobisíková, Miluše, Domboróczki, László, Drinkall, Gail, Đukić, Ana, Edwards, Ceiridwen J, Ernée, Michal, Evans, Christopher, Evans, Jane, Fernández-Götz, Manuel, Filipović, Slavica, Fitzpatrick, Andrew, Fokkens, Harry, Fowler, Chris, Fox, Allison, Gallina, Zsolt, Gamble, Michelle, González Morales, Manuel R, González-Rabanal, Borja, Green, Adrian, Gyenesei, Katalin, Habermehl, Diederick, Hajdu, Tamás, Hamilton, Derek, Harris, James, Hayden, Chris, Hendriks, Joep, Hernu, Bénédicte, Hey, Gill, Horňák, Milan, Ilon, Gábor, Istvánovits, Eszter, Jones, Andy M, Kavur, Martina Blečić, Kazek, Kevin, Kenyon, Robert A, Khreisheh, Amal, Kiss, Viktória, Kleijne, Jos, Knight, Mark, Kootker, Lisette M, Kovács, Péter F, Kozubová, Anita, Kulcsár, Gabriella, Kulcsár, Valéria, Le Pennec, Christophe, Legge, Michael, Leivers, Matt, Loe, Louise, López-Costas, Olalla, Lord, Tom, Los, Dženi, Lyall, James, Marín-Arroyo, Ana B, Mason, Philip, Matošević, Damir, Maxted, Andy, McIntyre, Lauren, McKinley, Jacqueline, McSweeney, Kathleen, Meijlink, Bernard, Mende, Balázs G, Menđušić, Marko, Metlička, Milan, Meyer, Sophie, Mihovilić, Kristina, Milasinovic, Lidija, Minnitt, Steve, Moore, Joanna, Morley, Geoff, Mullan, Graham, Musilová, Margaréta, Neil, Benjamin, Nicholls, Rebecca, Novak, Mario, Pala, Maria, Papworth, Martin, Paresys, Cécile, Patten, Ricky, Perkić, Domagoj, Pesti, Krisztina, Petit, Alba, Petriščáková, Katarína, Pichon, Coline, Pickard, Catriona, Pilling, Zoltán, Price, T Douglas, Radović, Siniša, Redfern, Rebecca, Resutík, Branislav, Rhodes, Daniel T, Richards, Martin B, Roberts, Amy, Roefstra, Jean, Sankot, Pavel, Šefčáková, Alena, Sheridan, Alison, Skae, Sabine, Šmolíková, Miroslava, Somogyi, Krisztina, Somogyvári, Ágnes, Stephens, Mark, Szabó, Géza, Szécsényi-Nagy, Anna, Szeniczey, Tamás, Tabor, Jonathan, Tankó, Károly, Maria, Clenis Tavarez, Terry, Rachel, Teržan, Biba, Teschler-Nicola, Maria, Torres-Martínez, Jesús F, Trapp, Julien, Turle, Ross, Ujvári, Ferenc, van der Heiden, Menno, Veleminsky, Petr, Veselka, Barbara, Vytlačil, Zdeněk, Waddington, Clive, Ware, Paula, Wilkinson, Paul, Wilson, Linda, Wiseman, Rob, Young, Eilidh, Zaninović, Joško, Žitňan, Andrej, Lalueza-Fox, Carles, de Knijff, Peter, Barnes, Ian, Halkon, Peter, Thomas, Mark G, Kennett, Douglas J, Cunliffe, Barry, Lillie, Malcolm, Rohland, Nadin, Pinhasi, Ron, Armit, Ian, Reich, David, Patterson, Nick, Isakov, Michael, Booth, Thomas, Büster, Lindsey, Fischer, Claire-Elise, Olalde, Iñigo, Ringbauer, Harald, Akbari, Ali, Cheronet, Olivia, Bleasdale, Madeleine, Adamski, Nicole, Altena, Eveline, Bernardos, Rebecca, Brace, Selina, Broomandkhoshbacht, Nasreen, Callan, Kimberly, Candilio, Francesca, Culleton, Brendan, Curtis, Elizabeth, Demetz, Lea, Carlson, Kellie Sara Duffett, Fernandes, Daniel M, Foody, M George B, Freilich, Suzanne, Goodchild, Helen, Kearns, Aisling, Lawson, Ann Marie, Lazaridis, Iosif, Mah, Matthew, Mallick, Swapan, Mandl, Kirsten, Micco, Adam, Michel, Megan, Morante, Guillermo Bravo, Oppenheimer, Jonas, Özdoğan, Kadir Toykan, Qiu, Lijun, Schattke, Constanze, Stewardson, Kristin, Workman, J Noah, Zalzala, Fatma, Zhang, Zhao, Agustí, Bibiana, Allen, Tim, Almássy, Katalin, Amkreutz, Luc, Ash, Abigail, Baillif-Ducros, Christèle, Barclay, Alistair, Bartosiewicz, László, Baxter, Katherine, Bernert, Zsolt, Blažek, Jan, Bodružić, Mario, Boissinot, Philippe, Bonsall, Clive, Bradley, Pippa, Brittain, Marcus, Brookes, Alison, Brown, Fraser, Brown, Lisa, Brunning, Richard, Budd, Chelsea, Burmaz, Josip, Canet, Sylvain, Carnicero-Cáceres, Silvia, Čaušević-Bully, Morana, Chamberlain, Andrew, Chauvin, Sébastien, Clough, Sharon, Čondić, Natalija, Coppa, Alfredo, Craig, Oliver, Črešnar, Matija, Cummings, Vicki, Czifra, Szabolcs, Danielisová, Alžběta, Daniels, Robin, Davies, Alex, de Jersey, Philip, Deacon, Jody, Deminger, Csilla, Ditchfield, Peter W, Dizdar, Marko, Dobeš, Miroslav, Dobisíková, Miluše, Domboróczki, László, Drinkall, Gail, Đukić, Ana, Edwards, Ceiridwen J, Ernée, Michal, Evans, Christopher, Evans, Jane, Fernández-Götz, Manuel, Filipović, Slavica, Fitzpatrick, Andrew, Fokkens, Harry, Fowler, Chris, Fox, Allison, Gallina, Zsolt, Gamble, Michelle, González Morales, Manuel R, González-Rabanal, Borja, Green, Adrian, Gyenesei, Katalin, Habermehl, Diederick, Hajdu, Tamás, Hamilton, Derek, Harris, James, Hayden, Chris, Hendriks, Joep, Hernu, Bénédicte, Hey, Gill, Horňák, Milan, Ilon, Gábor, Istvánovits, Eszter, Jones, Andy M, Kavur, Martina Blečić, Kazek, Kevin, Kenyon, Robert A, Khreisheh, Amal, Kiss, Viktória, Kleijne, Jos, Knight, Mark, Kootker, Lisette M, Kovács, Péter F, Kozubová, Anita, Kulcsár, Gabriella, Kulcsár, Valéria, Le Pennec, Christophe, Legge, Michael, Leivers, Matt, Loe, Louise, López-Costas, Olalla, Lord, Tom, Los, Dženi, Lyall, James, Marín-Arroyo, Ana B, Mason, Philip, Matošević, Damir, Maxted, Andy, McIntyre, Lauren, McKinley, Jacqueline, McSweeney, Kathleen, Meijlink, Bernard, Mende, Balázs G, Menđušić, Marko, Metlička, Milan, Meyer, Sophie, Mihovilić, Kristina, Milasinovic, Lidija, Minnitt, Steve, Moore, Joanna, Morley, Geoff, Mullan, Graham, Musilová, Margaréta, Neil, Benjamin, Nicholls, Rebecca, Novak, Mario, Pala, Maria, Papworth, Martin, Paresys, Cécile, Patten, Ricky, Perkić, Domagoj, Pesti, Krisztina, Petit, Alba, Petriščáková, Katarína, Pichon, Coline, Pickard, Catriona, Pilling, Zoltán, Price, T Douglas, Radović, Siniša, Redfern, Rebecca, Resutík, Branislav, Rhodes, Daniel T, Richards, Martin B, Roberts, Amy, Roefstra, Jean, Sankot, Pavel, Šefčáková, Alena, Sheridan, Alison, Skae, Sabine, Šmolíková, Miroslava, Somogyi, Krisztina, Somogyvári, Ágnes, Stephens, Mark, Szabó, Géza, Szécsényi-Nagy, Anna, Szeniczey, Tamás, Tabor, Jonathan, Tankó, Károly, Maria, Clenis Tavarez, Terry, Rachel, Teržan, Biba, Teschler-Nicola, Maria, Torres-Martínez, Jesús F, Trapp, Julien, Turle, Ross, Ujvári, Ferenc, van der Heiden, Menno, Veleminsky, Petr, Veselka, Barbara, Vytlačil, Zdeněk, Waddington, Clive, Ware, Paula, Wilkinson, Paul, Wilson, Linda, Wiseman, Rob, Young, Eilidh, Zaninović, Joško, Žitňan, Andrej, Lalueza-Fox, Carles, de Knijff, Peter, Barnes, Ian, Halkon, Peter, Thomas, Mark G, Kennett, Douglas J, Cunliffe, Barry, Lillie, Malcolm, Rohland, Nadin, Pinhasi, Ron, Armit, Ian, and Reich, David

Abstract

Present-day people from England and Wales harbour more ancestry derived from Early European Farmers (EEF) than people of the Early Bronze Age . To understand this, we generated genome-wide data from 793 individuals, increasing data from the Middle to Late Bronze and Iron Age in Britain by 12-fold, and Western and Central Europe by 3.5-fold. Between 1000 and 875 BC, EEF ancestry increased in southern Britain (England and Wales) but not northern Britain (Scotland) due to incorporation of migrants who arrived at this time and over previous centuries, and who were genetically most similar to ancient individuals from France. These migrants contributed about half the ancestry of Iron Age people of England and Wales, thereby creating a plausible vector for the spread of early Celtic languages into Britain. These patterns are part of a broader trend of EEF ancestry becoming more similar across central and western Europe in the Middle to Late Bronze Age, coincident with archaeological evidence of intensified cultural exchange . There was comparatively less gene flow from continental Europe during the Iron Age, and Britain's independent genetic trajectory is also reflected in the rise of the allele conferring lactase persistence to ~50% by this time compared to ~7% in central Europe where it rose rapidly in frequency only a millennium later. This suggests that dairy products were used in qualitatively different ways in Britain and in central Europe over this period. [Abstract copyright: © 2021. The Author(s), under exclusive licence to Springer Nature Limited.]

Published
2021

93. Robotrucks Will Crisscross The Country

Author

Davies, Alex

Subjects
Long haul trucking -- Forecasts and trends -- Innovations, Driverless trucks -- Forecasts and trends, Market trend/market analysis, Computers, Hobbies and crafts, Sociology and social work
Abstract

Byline: BY ALEX DAVIES SAMMY HARKHAM Robotrucks Will Crisscross the Country psdSAMMY HARKHAM60 The long-haul trucking industry is rumbling toward a crisis. The general crumminess of the job-weeks at a [...]

Published
2018

98. Forced activation of Wnt signaling alters morphogenesis and sensory organ identity in the chicken inner ear

Author

Stevens, Craig B., Davies, Alex L., Battista, Sarah, Lewis, Julian H., and Fekete, Donna M.

Subjects
Chickens -- Genetic aspects, Chickens -- Research, Ear -- Research, Morphogenesis -- Research, Biological sciences
Abstract

Components of the Wnt signaling pathway are expressed in the developing inner ear. To explore their role in ear patterning, we used retroviral gene transfer to force the expression of an activated form of [beta]-catenin that should constitutively activate targets of the canonical Wnt signaling pathway. At embryonic day 9 (E9) and beyond, morphological defects were apparent in the otic capsule and the membranous labyrinth, including ectopic and fused sensory patches. Most notably, the basilar papilla, an auditory organ, contained infected sensory patches with a vestibular phenotype. Vestibular identity was based on: (1) stereociliary bundle morphology; (2) spacing of hair cells and supporting cells; (3) the presence of otoliths; (4) immunolabeling indicative of vestibular supporting cells; and (5) expression of Msx1, a marker of certain vestibular sensory organs. Retrovirus-mediated misexpression of Wnt3a also gave rise to ectopic vestibular patches in the cochlear duct. In situ hybridization revealed that genes for three Frizzled receptors, c-Fz1, c-Fz7, and c-Fz10, are expressed in and adjacent to sensory primordia, while Wnt4 is expressed in adjacent, nonsensory regions of the cochlear duct. We hypothesize that Wnt/[beta]-catenin signaling specifies otic epithelium as macular and helps to define and maintain sensory/nonsensory boundaries in the cochlear duct. Keywords: [beta]-Catenin; Wnt3a; Wnt4; Msx1; p75ngfr; Frizzled; Serrate; Inner ear development; Cochlea; Hearing; Vestibular

Published
2003

99. Exploring the Relationship Between Palatal Cleft Type and Width With the Use of Relieving Incisions in Primary Repair.

Author

Davies, Alex, Davies, Amy, Wren, Yvonne, Deacon, Scott, Cobb, Alistair R.M., and Chummun, Shaheel

Subjects
CLEFT palate, PLASTIC surgery, RETROSPECTIVE studies, ACQUISITION of data, SURGERY, PATIENTS, TREATMENT effectiveness, SURGICAL site, MEDICAL records, PALATE
Abstract

Objective: The mainstay of palatal repair in the United Kingdom is the intravelar veloplasty (IVVP). It is not always possible to align the oral mucosa in the midline to achieve tension-free repair. The addition of lateral relieving incisions may aid transposition of the oral mucosa to allow closure. The aim of this study was to explore cleft features that may predispose to a requirement for relieving incisions in order to allow palate closure. Design: We performed a national multiinstitutional retrospective study using data from the UK Cleft Collective cohort study. Patients: The study sample consisted of 474 patients who had undergone IVVP at the time of palatal closure across all 16 of the UK cleft units. Results: We found strong evidence for the requirement for relieving incisions in patients with an increased degree of clefting per the Veau classification (P <.001), increasing palatal soft-edge width (P <.001) and moderate evidence of an associated use in patients with Pierre Robin sequence (P =.015). Insufficient data were available to explore the relationship between intertuberosity distance and the presence of fistula formation with the use of relieving incisions. Conclusions: The results of this study identify cleft features that increase the likelihood for requiring lateral relieving incisions to allow palatal closure. The degree to which the addition of relieving incisions to IVVP affects maxillary growth and speech outcomes is unknown. Further study is required to answer this important question. [ABSTRACT FROM AUTHOR]

Published
2022
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