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The durability of the bond strength developed between 2-cyanoacrylate esters and bone has been determined by aging specimens in water. One-day bond strength of the isobutyl and isomeric amyl 2-cyanoacrylates varied from 6.2 to 7.2 MPa. The strength of the bond decreased on storage or on thermocycling in water. Hydrolytic stability increased with increasing length of the alkyl ester group. After a six-month storage in water the various amyl 2-cyanoacrylates retained from 70% to 73% of their one-day bond strength. Pretreatment of the bone surface prior to application of the adhesive did not prove beneficial. The cured 2-cyanoacrylate can be removed from the substrate surface by appropriate solvents. Thus, it is not bonded covalently to bone. The bond strength, especially of the isobutyl and amyl 2-cyanoacrylates to bone in an aqueous environment, appears to be superior to other adhesives. Provided these monomers are biocompatible, they may be useful clinically where an intermediate-term adhesion is desired.

Effected two studies in a prison setting to determine the effectiveness of self-control procedures with institutionalized cigarette smokers. In Study I, 14 male inmates were given instruction in self-control techniques. The 6 inmates who completed treatment manifested significant reductions in their cigarette smoking. Intercorrelations between goal setting and smoking rates suggested the efficacy of a changing criterion schedule. A second study replicated Study I and suggested an appreciable (p less than .06) locus of control X type of goal setting (therapist vs. client) interaction. Study II also showed: (1) some components of treatment were perceived as significantly more helpful than others; (2) self-control treatment seemed effective with a pipe smoker; and (3) in comparison to Study I a relatively low drop-out rate occurred in this study, which used a contracting procedure to discourage drop-outs. Results are discussed in terms of treatment implications for inmate smokers, and suggestions for further research were provided.