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933 results on '"Collet L"'

56. 925P Efficacy of 2nd line treatment with chemotherapy (CT) or immune checkpoint inhibitors (ICIs) for patients (pts) with a prolonged objective response (>6 months) after 1st line therapy for recurrent or metastatic head & neck squamous cell carcinoma (R/M-HNSCC)

Author

Vienne, A., primary, Collet, L., additional, Chevalier, T., additional, Borel, C., additional, Tardy, M.P., additional, Huguet, F., additional, Richard, S., additional, Salas, S., additional, Saada-Bouzid, E., additional, Fayette, J., additional, and Daste, A., additional

Published
2020
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65. Normative Findings of Electrically Evoked Compound Action Potential Measurements Uing the Neural Response Telemetry of the Nucleus CI24M Cochlear Implant System

Author

Dees, D. Cafarelli, Dillier, N., Lai, W. K., von Wallenberg, E., van Dijk, B., Akdas, F., Aksit, M., Batman, C., Beynon, A., Burdo, S., Chanal, J.-M., Collet, L., Conway, M., Coudert, C., Craddock, L., Cullington, H., Deggouj, N., Fraysse, B., Grabel, S., Kiefer, J., Kiss, J. G., Lenarz, T., Mair, A., Maune, S., Müller-Deile, J., Piron, J.-P., Razza, S., Tasche, C., Thai-Van, H., Toth, F., Truy, E., Uziel, A., and Smoorenburg, G. F.

Published
2005

66. Spatio-temporal analysis of compound hydro-hazard extremes across the UK

Author

Visser-Quinn, A., Beevers, L., Collet, L., Formetta, G., Smith, K., Wanders, N., Thober, Stephan, Pan, M., Kumar, Rohini, Visser-Quinn, A., Beevers, L., Collet, L., Formetta, G., Smith, K., Wanders, N., Thober, Stephan, Pan, M., and Kumar, Rohini

Abstract

There exists an increasing need to understand the impact of climate change on the hydrological extremes of flood and drought, collectively referred to as ‘hydro-hazards’. At present, current methodology are limited in their scope, particularly with respect to inadequate representation of the uncertainty in the hydroclimatological modelling chain.This paper proposes spatially consistent comprehensive impact and uncertainty methodological framework for the identification of compound hydro-hazard hotspots – hotspots of change where concurrent increase in mean annual flood and drought events is projected. We apply a quasi-ergodic analysis of variance (QE-ANOVA) framework, to detail both the magnitude and the sources of uncertainty in the modelling chain for the mean projected mean change signal whilst accounting for non-stationarity. The framework is designed for application across a wide geographical range and is thus readily transferable. We illustrate the ability of the framework through application to 239 UK catchments based on hydroclimatological projections from the EDgE project (5 CMI5-GCMs and 3 HMs, forced under RCP8.5).The results indicate that half of the projected hotspots are temporally concurrent or temporally successive within the year, exacerbating potential impacts on society. The north-east of Scotland and south-west of the UK were identified as spatio-temporally compound hotspot regions and are of particular concern. This intensification of the hydrologic dynamic (timing and seasonality of hydro-hazards) over a limited time frame represents a major challenge for future water management.Hydrological models were identified as the largest source of variability, in some instances exceeding 80% of the total variance. Critically, clear spatial variability in the sources of modelling uncertainty was also observed; highlighting the need to apply a spatially consistent methodology, such as that presented. This application raises important questions regarding t

Published
2019

73. Angiostrongyliasis due to A. cantonensis: first evidence in French Territories of America& an up-date in all French Overseas Territories

Author

Dard, C., Nguyen, D., Miossec, C., Tessier, E., de Meuron, K., Harrois, D., Mattera, D., Epelboin, Loïc, Demar, Magalie Pierre, Blanchet, Denis, Elenga, N., Defo, A., Nicolas, M., Desprez, P., Rulquin, L., Tournier, S., Aubert, L., Traversier, N., Jaffar Bandjee, M.C., Belmonte, O., Miltgen, G., Collet, L., Blondé, R., Chamouine, Abdourahim, Benoit-Cattin, T., Olivier, C., Giard, M., Guerin, A., Ghawche, F., Darteyre, S., Larre, P., Sookhareea, C., Pasche, J., Oehler, E., Delvallez, G., Gourinat, A.C., Lastère, S., Desbois-Nogard, N., Matillon, Mirlène, Unité des Maladies Infectieuses et Tropicales (UMIT), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Université de Guyane (UG), Laboratoire Hospitalier et Universitaire Parasitologie Mycologie, and Centre Hospitalier de Mayotte

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

89. Les oto-émissions acoustiques chez l'humain

Author

Collet L

Subjects
medicine.anatomical_structure, Organ of Corti, Olivocochlear system, otorhinolaryngologic diseases, medicine, Otoacoustic emission, sense organs, General Medicine, Biology, Outer hair cells, Neuroscience, Cochlea
Abstract

Otoacoustic emissions are sounds emitted by the cochlea, basically deriving from the active micromechanical properties of the outer hair cells of the organ of Corti. As they can be recorded painlessly and non-intrusively, they provide a good means of studying human cochlear functioning. In this report, the main types of otoacoustic emission are described, with their characteristics and relation to cochlear functioning. The contribution of otoacoustic emission studies to the physiology of the medial olivocochlear system is discussed, this being the only sensitive and non-intrusive way of studying this system, the function of which remains uncertain.

Published
1994

92. Speech auditory brainstem response (speech ABR) characteristics depending on recording conditions, and hearing status An experimental parametric study

Author

Akhoun, I., Moulin, A., Jeanvoine, A., Menard, M., Buret, F., Vollaire, C., Scorretti, R., Veuillet, E., Berger-Vachon, C., Collet, L., Thai-Van, H., Neurosciences Sensorielles Comportement Cognition, Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon, IFR des neurosciences de Lyon (IFNL), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier le Vinatier [Bron]-Hospices Civils de Lyon (HCL)-Université Claude Bernard Lyon 1 (UCBL), Audiologie & Exploration Orofaciale, Hospices Civils de Lyon (HCL), Ampère (AMPERE), École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Claude Bernard Lyon 1 (UCBL), and Université de Lyon-Université de Lyon-Hospices Civils de Lyon (HCL)-Centre Hospitalier le Vinatier [Bron]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Adult, Male, PITCH, REPRESENTATION, Auditory Pathways, ARTIFACT, POTENTIALS, LANGUAGE, TONES, Hearing Loss, Unilateral, Electromagnetic leakage, MUSIC, Young Adult, Evoked Potentials, Auditory, Brain Stem, Reaction Time, otorhinolaryngologic diseases, Humans, Speech, Analysis of Variance, Artefact, Auditory Threshold, FREQUENCY-FOLLOWING RESPONSE, Auditory brainstem response, Middle Aged, Audiometry, Evoked Response, Acoustic Stimulation, Speech Perception, Unilateral deafness, Female, sense organs, Psychoacoustics
Abstract

International audience; Speech elicited auditory brainstem responses (Speech ABR) have been shown to be an objective measurement of speech processing in the brainstem. Given the simultaneous stimulation and recording, and the similarities between the recording and the speech stimulus envelope, there is a great risk of artefactual recordings. This study sought to systematically investigate the source of artefactual contamination in Speech ABR response. In a first part, we measured the sound level thresholds over which artefactual responses were obtained, for different types of transducers and experimental setup parameters. A watermelon model was used to model the human head susceptibility to electromagnetic artefact. It was found that impedances between the electrodes had a great effect on electromagnetic susceptibility and that the most prominent artefact is due to the transducer's electromagnetic leakage. The only artefact-free condition was obtained with insert-earphones shielded in a Faraday cage linked to common ground. In a second part of the study, using the previously defined artefact-free condition, we recorded speech ABR in unilateral deaf subjects and bilateral normal hearing subjects. In an additional control condition, Speech ABR was recorded with the insert-earphones used to deliver the stimulation, unplugged from the ears, so that the subjects did not perceive the stimulus. No responses were obtained from the deaf ear of unilaterally hearing impaired subjects, nor in the insert-out-of-the-ear condition in all the subjects, showing that Speech ABR reflects the functioning of the auditory pathways.

Published
2008

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