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487 results on '"Cho, Hee-Yeon"'

59. An alternative route towards socialization of democracy in Asia: review ofLiberalism Disavowed: Communitarianism and State Capitalism in Singaporeby Chua Beng Huat

Author

Cho Hee-Yeon and Jang Hun-Gyo

Subjects
Cultural Studies, Liberalism, Hegemony, Communitarianism, media_common.quotation_subject, Political science, Political economy, Socialization (Marxism), State capitalism, Democracy, media_common
Abstract

The contribution of Chua’s Liberalism Disavowed is very large in that it shows how the hegemony of the PAP is working and resisting liberalism, especially in the everyday world of Singaporeans. It ...

Published
2018
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61. Enhanced brain delivery and therapeutic activity of trastuzumab after blood-brain barrier opening by NEO100 in mouse models of brain-metastatic breast cancer

Author

Wang, Weijun, primary, He, Haiping, additional, Marín-Ramos, Nagore I, additional, Zeng, Shan, additional, Swenson, Steven D, additional, Cho, Hee-Yeon, additional, Fu, Jie, additional, Beringer, Paul M, additional, Neman, Josh, additional, Chen, Ligang, additional, Schönthal, Axel H, additional, and Chen, Thomas C, additional

Published
2021
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62. Regulation of expression of cellulosomes and noncellulosomal (hemi)cellulolytic enzymes in Clostridium cellulovorans during growth on different carbon sources

Author

Han, Sung Ok, Cho, Hee-Yeon, Yukawa, Hideaki, Inui, Masayuki, and Doi, Roy H.

Subjects
Microbial enzymes -- Research, Clostridium -- Research, Clostridium -- Physiological aspects, Biological sciences
Abstract

Cellulosomes and noncellulosomal (hemi)cellulolytic enzymes are produced by Clostridium cellulovorans to degrade plant cell walls. To understand their synergistic relationship, changes in mRNA and protein expression in cellulosomes and noncellulosomal (hemi)cellulolytic enzymes (hereafter called noncellulosomal enzymes) of cultures grown on cellobiose, cellulose, pectin, xylan, and corn fiber or mixtures thereof were examined. Cellulase expression, favored particularly by the presence of Avicel, was found with all substrates. Comparison of cellulosome and noncellulosomal enzymes showed that expression profiles were strongly affected by the carbon source. High xylanase or pectate lyase expression was observed when C. cellulovorans was grown on xylan or pectin, respectively. Mixed carbon substrates (cellulose-pectin-xylan mixture or corn fiber) induced a wider variety of enzymes than a single carbon source, such as cellobiose, pectin, or xylan. Cellulosomal proteome profiles were more affected by the carbon source than the noncellulosomal enzymes. Transcription and protein analyses revealed that cellulosomes and noncellulosomal enzymes were expressed simultaneously on mixed carbon sources, but their degree of inducibility varied when the substrate was either cellulose or cellobiose. Cellulosomes and noncellulosomal enzymes had synergistic activity on various carbon substrates. These results indicated that expression of plant cell wall-degrading enzymes is highly influenced by the available carbon source and that synergy between cellulosomes and noncellulosomal enzymes contribute to plant cell wall degradation.

Published
2004

64. Genetic basis of Bartter syndrome in Korea

Author

Lee, Beom Hee, Cho, Hee Yeon, Lee, HyunKyung, Han, Kyoung Hee, Kang, Hee Gyung, Ha, Il Soo, Lee, Joo Hoon, Park, Young Seo, Shin, Jae Il, Lee, Dae-Yeol, Kim, Su-Yung, Choi, Yong, and Cheong, Hae Il

Published
2012
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65. Modulation of the multisubstrate specificity of Thermus maltogenic amylase by truncation of the N-terminal domain and by a salt-induced shift of the monomer/dimer equilibrium

Author

Kim, Tae-Jip, Nguyen, Van Dao, Lee, Hee-Scob, Kim, Myo-Jeong, Cho, Hee-Yeon, Kim, Young-Wan, Moon, Tae-Wha, Park, Cheon Seok, Kim, Jung-Wan, Oh, Byung-Ha, Lee, Soo-Bok, Svensson, Brite, and Park, Kwan-Hwa

Subjects
Amylases -- Research, Enzymes -- Structure-activity relationship, Structure-activity relationships (Biochemistry) -- Analysis, Enzyme kinetics -- Analysis, Biological sciences, Chemistry
Abstract

Results show that Thermus maltogenic amylase monomer and dimer both are enzymatically active with different substrate preferences. Furthermore, wild-type and truncated enzymes exhibit different kinetics and specific activities with multisubstrate specificity of the N-terminal domain.

Published
2001

67. Diagnostic yield and clinical utility of whole exome sequencing using an automated variant prioritization system, EVIDENCE

Author

Seo, Go Hun, primary, Kim, Taeho, additional, Choi, In Hee, additional, Park, Jung‐young, additional, Lee, Jungsul, additional, Kim, Sehwan, additional, Won, Dhong‐gun, additional, Oh, Arum, additional, Lee, Yena, additional, Choi, Jeongmin, additional, Lee, Hajeong, additional, Kang, Hee Gyung, additional, Cho, Hee Yeon, additional, Cho, Min Hyun, additional, Kim, Yoon Jeon, additional, Yoon, Young Hee, additional, Eun, Baik‐Lin, additional, Desnick, Robert J., additional, Keum, Changwon, additional, and Lee, Beom Hee, additional

Published
2020
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72. High Diagnostic Yield and Clinical Utility of Whole Exome Sequencing Using an Automated Variant Prioriti S Ation System, EVIDENCE, for Patients with Suspected Genetic Disorders

Author

Seo, Go Hun, primary, Kim, Taeho, additional, Park, Jung-young, additional, Lee, Jungsul, additional, Kim, Sehwan, additional, Won, Dhong-gun, additional, Oh, Arum, additional, Lee, Yena, additional, Choi, In Hee, additional, Choi, Jeongmin, additional, Lee, Hajeong, additional, Kang, Hee Gyung, additional, Cho, Hee Yeon, additional, Cho, Min Hyun, additional, Kim, Yoon Jeon, additional, Yoon, Young Hee, additional, Eun, Baik-Lin, additional, Desnick, Robert J., additional, Keum, Changwon, additional, and Lee, Beom Hee, additional

Published
2020
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81. Pilot study of EVIDENCE: High diagnostic yield and clinical utility of whole exome sequencing using an automated interpretation system for patients with suspected genetic disorders

Author

Seo, Go Hun, primary, Kim, Taeho, additional, Park, Jung-young, additional, Lee, Jungsul, additional, Kim, Sehwan, additional, Won, Dhong-gun, additional, Oh, Arum, additional, Lee, Yena, additional, Choi, In Hee, additional, Choi, Jeongmin, additional, Lee, Hajeong, additional, Kang, Hee Gyung, additional, Cho, Hee Yeon, additional, Cho, Min Hyun, additional, Kim, Yoon Jeon, additional, Yoon, Young Hee, additional, Eun, Baik-Lin, additional, Desnick, Robert J, additional, Keum, Changwon, additional, and Lee, Beom Hee, additional

Published
2019
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85. Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus

Author

Balmain Allan, Mao Jian-Hua, Cho Hee-Yeon, Gladman Nicholas, Dworkin Amy M, Fleming Jessica L, Mahler Kimberly L, and Toland Amanda

Subjects
Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background Mus spretus diverged from Mus musculus over one million years ago. These mice are genetically and phenotypically divergent. Despite the value of utilizing M. musculus and M. spretus for quantitative trait locus (QTL) mapping, relatively little genomic information on M. spretus exists, and most of the available sequence and polymorphic data is for one strain of M. spretus, Spret/Ei. In previous work, we mapped fifteen loci for skin cancer susceptibility using four different M. spretus by M. musculus F1 backcrosses. One locus, skin tumor susceptibility 5 (Skts5) on chromosome 12, shows strong linkage in one cross. Results To identify potential candidate genes for Skts5, we sequenced 65 named and unnamed genes and coding elements mapping to the peak linkage area in outbred spretus, Spret/EiJ, FVB/NJ, and NIH/Ola. We identified polymorphisms in 62 of 65 genes including 122 amino acid substitutions. To look for polymorphisms consistent with the linkage data, we sequenced exons with amino acid polymorphisms in two additional M. spretus strains and one additional M. musculus strain generating 40.1 kb of sequence data. Eight candidate variants were identified that fit with the linkage data. To determine the degree of variation across M. spretus, we conducted phylogenetic analyses. The relatedness of the M. spretus strains at this locus is consistent with the proximity of region of ascertainment of the ancestral mice. Conclusion Our analyses suggest that, if Skts5 on chromosome 12 is representative of other regions in the genome, then published genomic data for Spret/EiJ are likely to be of high utility for genomic studies in other M. spretus strains.

Published
2008
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88. Is democracy with Chinese characteristics possible? A theoretical and practical reflection of crisis in the Chinese party-state regime and post-revolutionary socialist hegemonic politics

Author

Cho Hee-Yeon

Subjects
Cultural Studies, media_common.quotation_subject, Democracy, Politics, Socialism, State (polity), Political economy, Socialist market economy, Marxist philosophy, Sociology, Political philosophy, Economic system, China, media_common
Abstract

This article discusses political challenges to the current party-state regime in China and the direction of its new political reform, on the one hand, and tries to theorize a post-revolutionary “socialist hegemonic politics” after the revolution, based on reinterpretation of Marxist political theory and Western democracy theory, on the other hand. It understands that there is a deeper crisis of Chinese politics, rather than simply providing an empirical analysis. In so doing, this article both reflects existing Marxist political theory and the concept of democracy while reconstructing both of them, interacting with the current Chinese political reality. Currently, the Chinese party-state regime is facing a compressed form of crisis due to rapid economic growth; that is, a kind of “success crisis.” The crisis is expressed in such phenomena as the breakdown of “identification of the party-state with society,” assumed since the revolution, the victimization of the working class and peasants, which ha...

Published
2014
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