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395 results on '"Carcassi, C"'

51. Susceptibility to human herpesvirus-8 infection in a healthy population from Sardinia is not directly correlated with the expression of HLA-DR alleles

Author

Alberto Faggioni, Cerimele D, Satta R, Carcassi C, Antonio Angeloni, Cottoni F, Ma Montesu, Roberta Santarelli, Stefania Uccini, and Mv Masala

Subjects
Adult, Aged, 80 and over, Pathology, medicine.medical_specialty, Adolescent, business.industry, Healthy population, Genes, MHC Class II, HLA-DR Antigens, Dermatology, Middle Aged, Italy, Herpesvirus 8, Human, Immunology, HLA-DR, Humans, Medicine, Genetic Predisposition to Disease, Allele, business, Sarcoma, Kaposi, Alleles, Human herpesvirus, Aged
Published
2004
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52. Killer immunoglobulin-like receptors can predict TKI treatment-free remission in chronic myeloid leukemia patients

Author

Caocci, G, Martino, B, Greco, M, Abruzzese, E, Trawinska, M, Lai, S, Ragatzu, P, Galimberti, S, Baratè, C, Mulas, O, Labate, C, Littera, R, Carcassi, C, GAMBACORTI PASSERINI, C, La Nasa, G, La Nasa, G., GAMBACORTI PASSERINI, CARLO, Caocci, G, Martino, B, Greco, M, Abruzzese, E, Trawinska, M, Lai, S, Ragatzu, P, Galimberti, S, Baratè, C, Mulas, O, Labate, C, Littera, R, Carcassi, C, GAMBACORTI PASSERINI, C, La Nasa, G, La Nasa, G., and GAMBACORTI PASSERINI, CARLO

Abstract

Several factors are predictive of treatment-free remission (TFR) in chronic myeloid leukemia (CML), but few data exist on the role of natural killer (NK) cells and their killer-cell immunoglobulin-like receptors (KIRs). KIR and human leukocyte antigen (HLA) genotypes were investigated in 36 CML patients who discontinued tyrosine kinase inhibitor (TKI) treatment after achieving deep molecular response (MR4.5). Cumulative TFR was significantly higher in patients homozygous for KIR A haplotype (85.7% vs. 45.5%; p = 0.029). Younger age, Bx haplotype, and the combination KIR3DS1/KIR3DL1 present/HLA-Bw4 present were significantly associated with relapse. KIR genotypes could prove useful in identifying patients that are likely to maintain MR4.5 after discontinuing TKI treatment.

Published
2015

53. Role of Killer cell immunoglobulin-like receptors and their HLA class I ligands in autoimmune hepatitis

Author

Littera, R., primary, Carcassi, C., additional, Secci, L., additional, Lai, S., additional, Cappai, L., additional, Porcella, R., additional, Alba, F., additional, Maddi, R., additional, Serra, M., additional, Cappellini, S., additional, Salustro, C., additional, Onali, S., additional, Balestrieri, C., additional, Serra, G., additional, Conti, M., additional, Zolfino, T., additional, Scioscia, R., additional, Barca, L., additional, and Chessa, L., additional

Published
2015
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54. Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation

Author

Crocchiolo, R., Zino, E., Vago, L., Oneto, R., Bruno, B., Pollichieni, S., Sacchi, N., Sormani, M. P., Marcon, J., Lamparelli, T., Fanin, R., Garbarino, L., Miotti, V., Bandini, G., Bosi, A., Ciceri, F., Bacigalupo, A., Fleischhauer, K., Midollo Osseo Gruppo Italiano Trapianto, D. I., Terapia Cellulare, Cellule Staminali Ematopoietiche Cse E., Italian Bone Marrow Donor Registry Collaboratori, Scalari P., Bontempelli, M., Prinoth, O., Carcassi, C., Marceno, R., Porfirio, Rombola, G., Lombardo, Ferrioli, G., Poli, F., Scalamogna, M., Mazzi, B., Rossi, F., Mascaretti, L., Albergoni, Salvaneschi, L., Salvaneschi, M., Valentini, Nesci, S., Papola, F., Scatena, Mariotti, Perrone, Laurenti, Grammatico, Paola, Mariani, M., Favoino, B., Guizzardi, Pontiero, Leoni, P., Rambaldi, A., Casini, M., Angelucci, E., Baronciani, D., La Nasa, G., Milone, G., Guidi, S., Van Lint, M. T., Dini, G., Corradini, P., Milani, R., Morra, E., Marenco, P., Deliliers, Lambretenghi G., Onida, F., Marcatti, M., Castagna, L., Pioltelli, P., Selleri, C., Zanesco, L., Scime, R., Musso, M., Alessandrino, E. P., Locatelli, F., Visani, G., Di Bartolomeo, P., Papineschi, F., Favre, C., Iori, A. P., Foa, Roberto, Locasciulli, A., Majolino, I., Majolino, P., Leone, G., Arcese, W., Cerretti, R., Carella, A. M., Cascavilla, N., Lauria, F., Mazza, P., Cerno, M., Benedetti, F., Crocchiolo, R, Zino, E, Vago, L, Oneto, R, Bruno, B, Pollichieni, S, Sacchi, N, Sormani, Mp, Marcon, J, Lamparelli, T, Fanin, R, Garbarino, L, Miotti, V, Bandini, G, Bosi, A, Ciceri, F, Bacigalupo, A, and Fleischhauer, K

Subjects
Adult, Disease-Free Survival, Donor Selection, Female, HLA-DRB1 Chains, Hematologic Neoplasms, Humans, Italy, Male, Middle Aged, Recurrence, Registries, Retrospective Studies, Risk Factors, Survival Rate, Transplantation, Homologous, Algorithms, HLA-DR Antigens, Hematopoietic Stem Cell Transplantation, Tissue Donors, Biochemistry, Immunology, Hematology, Cell Biology, Homologous, medicine.medical_treatment, Human leukocyte antigen, Hematopoietic stem cell transplantation, Medicine, Risk factor, Survival rate, Transplantation, HLA-DPB1, business.industry, Hazard ratio, Confidence interval, business, Settore MED/15 - Malattie del Sangue
Abstract

The importance of donor-recipient human leukocyte antigen (HLA)-DPB1 matching for the clinical outcome of unrelated hematopoietic stem cell transplantation (HSCT) is controversial. We have previously described an algorithm for nonpermissive HLA-DPB1 disparities involving HLA-DPB1*0901,*1001,*1701,*0301,*1401,*4501, based on T-cell alloreactivity patterns. By revisiting the immunogenicity of HLA-DPB1*02, a modified algorithm was developed and retrospectively tested in 621 unrelated HSCTs facilitated through the Italian Registry for onco-hematologic adult patients. The modified algorithm proved to be markedly more predictive of outcome than the original one, with significantly higher KaplanMeier probabilities of 2-year survival in permissive compared with nonpermissive transplantations (55% vs 39%, P = .005). This was the result of increased adjusted hazards of nonrelapse mortality (hazard ratio [HR] = 1.74; confidence interval [CI], 1.19-2.53; P = .004) but not of relapse (HR = 1.02; CI, 0.73-1.42; P = .92). The increase in the hazards of overall mortality by nonpermissive HLA-DPB1 disparity was similar in 10 of 10 (HR = 2.12; CI, 1.23-3.64; P = .006) and 9 of 10 allele-matched transplantations (HR = 2.21; CI, 1.28-3.80; P = .004), both in early-stage and in advanced-stage disease. These data call for revisiting current HLA matching strategies for unrelated HSCT, suggesting that searches should be directed up-front toward identification of HLA-DPB1 permissive, 10 of 10 or 9 of 10 matched donors. (Blood. 2009; 114:1437-1444) RI Porfirio, Berardino/I-1988-2012

Published
2009

55. Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation

Author

Crocchiolo, R, Zino, E, Vago, L, Oneto, R, Bruno, B, Pollichieni, S, Sacchi, N, Sormani, Mp, Marcon, J, Lamparelli, T, Fanin, R, Garbarino, L, Miotti, V, Bandini, G, Bosi, A, Ciceri, F, Bacigalupo, A, Fleischhauer, K, Gruppo Italiano Trapianto di Midollo Osseo, Terapia Cellulare, Cellule Staminale Ematopoietiche e., Italian Bone Marrow Donor Registry, Scalari, P, Bontempelli, M, Prinoth, O, Carcassi, C, Marcenò, R, Porfirio, Rombolà, G, Lombardo, Ferrioli, G, Poli, F, Scalamogna, M, Mazzi, B, Rossi, F, Mascaretti, L, Albergoni, Salvaneschi, L, Martinetti, M, Valentini, Renzo, Nesci, S, Papola, F, Scatena, Mariotti, Perrone, Laurenti, Grammatico, P, Mariani, M, Favoino, B, Guizzardi, Pontiero, Leoni, P, Rambaldi, A, Casini, M, Angelucci, E, Baronciani, D, La Nasa, G, Milone, G, Guidi, S, Van Lint MT, Dini, G, Corradini, P, Milani, R, Morra, E, Marenco, P, Lambretenghi Deliliers, G, Onida, F, Marcatti, M, Castagna, L, Pioltelli, P, Selleri, C, Zanesco, L, Scimè, R, Musso, M, Alessandrino, Ep, Locatelli, F, Visani, G, Di Bartolomeo, P, Papineschi, Federico, Favre, C, Iori, Ap, Foà, R, Locasciulli, A, Majolino, I, Majolino, P, Leone, G, Arcese, W, Cerretti, R, Carella, Am, Cascavilla, N, Lauria, F, Mazza, P, Cerno, M, and Benedetti, F.

Published
2009

56. RFLP Standardization Report for BF/PstI

Author

Hyldig-Nielsen, J. J., primary, Trucco, M., additional, Coppin, H., additional, Andreas-Zietz, A., additional, Keller, E., additional, Carcassi, C., additional, Takada, A., additional, and Svejgaard, A., additional

Published
1989
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57. RFLP Standardization Report for 210H/PstI

Author

Hyldig-Nielsen, J. J., primary, Trucco, M., additional, Coppin, H., additional, Andreas-Zietz, A., additional, Keller, E., additional, Carcassi, C., additional, Takada, A., additional, and Svejgaard, A., additional

Published
1989
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59. European Working Party on Systemic Lupus Erythematosus. Systemic lupus erythematosus in Europe at the change of the millennium: lessons from the 'Euro-Lupus Project'

Author

Cervera, R, ABARCA COSTALAGO, M, Abramovicz, D, Allegri, F, Annunziata, P, Aydintug, Ao, Bacarelli, Mr, Bellisai, F, Bernardino, I, BIERNAT KALUZA, E, Blockmans, D, Boki, K, Bracci, L, Campanella, V, Camps, Mt, Carcassi, C, Cattaneo, Roberto, Cauli, A, CHWALINSKA SADOWSKA, H, Contu, L, Cosyns, Jp, Danieli, Mg, Dcruz, D, Depresseux, G, Direskeneli, H, Domènech, I, Espinosa, G, FERNÁNDEZ NEBRO, A, Ferrara, Gb, Font, J, Frutos, Ma, Galeazzi, M, GARCÌA CARRASCO, M, GARCÍA IGLESIAS MF, GARCÍA TOBARUELA, A, George, J, Gil, A, GONZÁLEZ SANTOS, P, Grana, M, Gül, A, Haga, Hj, DE HARO LIGER, M, Houssiau, F, Hughes, Gr, Ingelmo, M, JEDRYKA GÓRAL, A, Khamashta, Ma, Lavilla, P, Levi, Y, LÓPEZ DULPA, M, LÓPEZ SOTO, A, Maldykowa, H, Marcolongo, R, Mathieu, A, Morozzi, G, Nicolopoulou, N, Papasteriades, C, Passiu, G, Perelló, I, Petera, P, Petrovic, R, Piette, Jc, Pintado, V, DE PITA, O, Popovic, R, Pucci, G, Puddu, P, DE RAMÓN, E, RAMOS CASALS, M, RODRÍGUEZ ANDREU, J, RUIZ IRASTORZA, G, SANCHEZ LORA, J, Sanna, G, Scorza, R, Sebastiani, Gd, Sherer, Y, Shoenfeld, Y, Simpatico, A, Sinico, Ra, Smolen, J, Tincani, Angela, Tokgöz, G, URBANO MÁRQUEZ, A, Vasconcelos, C, Vázquez, Jj, Veronesi, J, Vianna, J, and Vivancos, J.

Published
2006

60. Activating KIR molecules and their cognate ligands prevail in children with a diagnosis of ASD and in their mothers

Author

Guerini, Fr, Bolognesi, E, Chiappedi, M, Manca, S, Ghezzo, A, Agliardi, C, Zanette, Michela, Littera, R, Carcassi, C, Sotgiu, S, Clerici, M., Zanette, Michela (ORCID:0000-0002-6096-1896), Guerini, Fr, Bolognesi, E, Chiappedi, M, Manca, S, Ghezzo, A, Agliardi, C, Zanette, Michela, Littera, R, Carcassi, C, Sotgiu, S, Clerici, M., and Zanette, Michela (ORCID:0000-0002-6096-1896)

Abstract

The activity of natural killer (NK) cells is modulated by the interaction between killer-cell immune globulin-like receptor (KIR) proteins and their cognate HLA ligands; activated NK cells produce inflammatory cytokines and mediate innate immune responses. Activating KIR/HLA complexes (aKIR/HLA) were recently suggested to prevail in children with autism spectrum disorders (ASD), a neurodevelopmental syndrome characterized by brain and behavioral abnormalities and associated with a degree of inflammation. We verified whether such findings could be confirmed by analyzing two sample cohorts of Sardinian and continental Italian ASD children and their mothers. Results showed that aKIR/HLA are increased whereas inhibitory KIR/HLA complexes are reduced in ASD children; notably this skewing was even more significant in their mothers. KIR and HLA molecules are expressed by placental cells and by the trophoblast and their interactions result in immune activation and influence fetal, as well as central nervous system development and plasticity. Data herein suggest that in utero KIR/HLA immune interactions favor immune activation in ASD; this may play a role in the pathogenesis of the disease.

Published
2014

61. Activating KIR molecules and their cognate ligands prevail in children with a diagnosis of ASD and in their mothers.

Author

Guerini, F. R., Bolognesi, E., Chiappedi, M., Manca, S., Ghezzo, A., Agliardi, C., Zanette, Michela, Littera, R., Carcassi, C., Sotgiu, S., Clerici, M., Zanette, Michela (ORCID:0000-0002-6096-1896), Guerini, F. R., Bolognesi, E., Chiappedi, M., Manca, S., Ghezzo, A., Agliardi, C., Zanette, Michela, Littera, R., Carcassi, C., Sotgiu, S., Clerici, M., and Zanette, Michela (ORCID:0000-0002-6096-1896)

Abstract

Activating KIR molecules and their cognate ligands prevail in children with a diagnosis of ASD and in their mothers.

Published
2014

65. European Working Party on Systemic Lupus Erythematosus. Lessons from the 'Euro-Lupus Cohort'

Author

Cervera, R, ABARCA COSTALAGO, M, Abramovicz, D, Allegri, F, Annunziata, P, Aydintug, Ao, Bacarelli, Mr, Bellisai, F, Bernardino, I, BIERNAT KALUZA, E, Blockmans, D, Boki, K, Bracci, L, Campanella, V, Camps, Mt, Carcassi, C, Cattaneo, Roberto, Cauli, A, CHWALINSKA SADOWSKA, H, Contu, L, Cosyns, Jp, Danieli, Mg, D'Cruz, D, Depresseux, G, Direskeneli, H, Domènech, I, Espinosa, G, FERNÁNDEZ NEBRO, A, Ferrara, Gb, Font, J, Frutos, Ma, Galeazzi, M, GARCÍA CARRASCO, M, GARCÍA IGLESIAS MF, GARCÍA TOBARUELA, A, George, J, Gil, A, GONZÁLEZ SANTOS, P, Grana, M, Gül, A, Haga, Hj, DE HARO LIGER, M, Houssiau, F, Hughes, Gr, Ingelmo, M, JEDRYKA GÓRAL, A, Khamashta, Ma, Lavilla, P, Levi, Y, LÓPEZ DUPLA, M, LÓPEZ SOTO, A, Maldykowa, H, Marcolongo, R, Mathieu, A, Morozzi, G, Nicolopoulou, N, Papasteriades, C, Passiu, G, Perelló, I, Petera, P, Petrovic, R, Piette, Jc, Pintado, V, DE PITA, O, Popovic, R, Pucci, G, Puddu, P, DE RAMÓN, E, RAMOS CASALS, M, RODRÍGUEZ ANDREU, J, RUIZ IRASTROZA, G, SÁNCHEZ LORA, J, Sanna, G, Scorza, R, Sebastini, Gd, Sherer, Y, Shoenfeld, Y, Simpatico, A, Sinico, Ra, Smolen, J, Tincani, Angela, Tokgöz, G, URBANO MÁRQUEZ, A, Vasconcelos, C, Vázquez, Jj, Veronesi, M, Vianni, J, and Vivancos, J.

Published
2002

66. The 312N variant of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) confers up to 2·7-fold increased risk of polycystic ovary syndrome in a Sardinian population

Author

Capalbo, Antonio, Sagnella, Francesca, Apa, Rosanna, Fulghesu, Am, Lanzone, Antonio, Morciano, Andrea, Farcomeni, A, Gangale, Mf, Moro, Francesca, Martinez, Daniela, Ciardulli, A, Palla, C, Uras, Ml, Spettu, F, Cappai, A, Carcassi, C, Neri, Geraldina, Tiziano, Francesco Danilo, Apa, Rosanna (ORCID:0000-0003-0143-9114), Lanzone, Antonio (ORCID:0000-0003-4119-414X), Tiziano, Francesco Danilo (ORCID:0000-0002-5545-6158), Capalbo, Antonio, Sagnella, Francesca, Apa, Rosanna, Fulghesu, Am, Lanzone, Antonio, Morciano, Andrea, Farcomeni, A, Gangale, Mf, Moro, Francesca, Martinez, Daniela, Ciardulli, A, Palla, C, Uras, Ml, Spettu, F, Cappai, A, Carcassi, C, Neri, Geraldina, Tiziano, Francesco Danilo, Apa, Rosanna (ORCID:0000-0003-0143-9114), Lanzone, Antonio (ORCID:0000-0003-4119-414X), and Tiziano, Francesco Danilo (ORCID:0000-0002-5545-6158)

Abstract

Polycystic ovary syndrome (PCOS) is a frequent condition, affecting about 15% of women of reproductive age. Because of its familial occurrence, a multifactorial model of susceptibility, including both genetic and environmental factors, has been proposed. However, the identification of genetic factors has been elusive.

Published
2012

73. The conundrum of HLA-DRB1*14:01/*14:54 and HLA-DRB3*02:01/*02:02 mismatches in unrelated hematopoietic SCT

Author

Pasi, A, primary, Crocchiolo, R, additional, Bontempelli, M, additional, Carcassi, C, additional, Carella, G, additional, Crespiatico, L, additional, Garbarino, L, additional, Mascaretti, L, additional, Mazzi, B, additional, Mazzola, G, additional, Miotti, V, additional, Porfirio, B, additional, Tagliaferri, C, additional, Valentini, T, additional, Vecchiato, C, additional, Fleischhauer, K, additional, Sacchi, N, additional, Bosi, A, additional, and Martinetti, M, additional

Published
2010
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76. Lessons from the 'Euro-Lupus Cohort'

Author

Cervera, R, Abarca Costalago, M, Abramovicz, D, Allegri, F, Annunziata, P, Aydintug, A, Bacarelli, M, Bellisai, F, Bernardino, I, Biernat Kaluza, E, Blockmans, D, Boki, K, Bracci, L, Campanella, V, Camps, M, Carcassi, C, Cattaneo, R, Cauli, A, Chwalinska Sadowska, H, Contu, L, Cosyns, J, Danieli, M, D'Cruz, D, Depresseux, G, Direskeneli, H, Domènech, I, Espinosa, G, Fernández Nebro, A, Ferrara, G, Font, J, Frutos, M, Galeazzi, M, García Carrasco, M, García Iglesias, M, García Tobaruela, A, George, J, Gil, A, González Santos, P, Grana, M, Gül, A, Haga, H, de Haro Liger, M, Houssiau, F, Hughes, G, Ingelmo, M, Jedryka Góral, A, Khamashta, M, Lavilla, P, Levi, Y, López Dupla, M, López Soto, A, Maldykowa, H, Marcolongo, R, Mathieu, A, Morozzi, G, Nicolopoulou, N, Papasteriades, C, Passiu, G, Perelló, I, Petera, P, Petrovic, R, Piette, J, Pintado, V, de Pita, O, Popovic, R, Pucci, G, Puddu, P, de Ramón, E, Ramos Casals, M, Rodríguez Andreu, J, Ruiz Irastroza, G, Sánchez Lora, J, Sanna, G, Scorza, R, Sebastini, G, Sherer, Y, Shoenfeld, Y, Simpatico, A, Sinico, R, Smolen, J, Tincani, A, Tokgöz, G, Urbano Márquez, A, Vasconcelos, C, Vázquez, J, Veronesi, M, Vianni, J, Vivancos, J, SINICO, RENATO ALBERTO, Vivancos, J., Cervera, R, Abarca Costalago, M, Abramovicz, D, Allegri, F, Annunziata, P, Aydintug, A, Bacarelli, M, Bellisai, F, Bernardino, I, Biernat Kaluza, E, Blockmans, D, Boki, K, Bracci, L, Campanella, V, Camps, M, Carcassi, C, Cattaneo, R, Cauli, A, Chwalinska Sadowska, H, Contu, L, Cosyns, J, Danieli, M, D'Cruz, D, Depresseux, G, Direskeneli, H, Domènech, I, Espinosa, G, Fernández Nebro, A, Ferrara, G, Font, J, Frutos, M, Galeazzi, M, García Carrasco, M, García Iglesias, M, García Tobaruela, A, George, J, Gil, A, González Santos, P, Grana, M, Gül, A, Haga, H, de Haro Liger, M, Houssiau, F, Hughes, G, Ingelmo, M, Jedryka Góral, A, Khamashta, M, Lavilla, P, Levi, Y, López Dupla, M, López Soto, A, Maldykowa, H, Marcolongo, R, Mathieu, A, Morozzi, G, Nicolopoulou, N, Papasteriades, C, Passiu, G, Perelló, I, Petera, P, Petrovic, R, Piette, J, Pintado, V, de Pita, O, Popovic, R, Pucci, G, Puddu, P, de Ramón, E, Ramos Casals, M, Rodríguez Andreu, J, Ruiz Irastroza, G, Sánchez Lora, J, Sanna, G, Scorza, R, Sebastini, G, Sherer, Y, Shoenfeld, Y, Simpatico, A, Sinico, R, Smolen, J, Tincani, A, Tokgöz, G, Urbano Márquez, A, Vasconcelos, C, Vázquez, J, Veronesi, M, Vianni, J, Vivancos, J, SINICO, RENATO ALBERTO, and Vivancos, J.

Abstract

The "Euro-Lupus Cohort" is composed by 1,000 patients with systemic lupus erythematosus (SLE) that have been followed prospectively since 1991. These patients have been gathered by a European consortium - the "Euro-Lupus Project Group". This consortium was originated as part of the network promoted by the "European Working Party on SLE", a working group created in 1990 in order to promote research in Europe on the different problems related to this disease. The "Euro-Lupus Cohort" provides an updated information on the SLE morbidity and mortality characteristics in the present decade as well as defines several clinical and immunological prognostic factors

Published
2002

81. Serological and molecular studies of HLA in Sardinian patients with Graves' disease

Author

Giorgio La Nasa, Martino E, Carcassi C, Mulargia M, Floris L, Vacca A, Baldini G, Orrù S, Ledda A, and Grasso L

Subjects
Adult, Aged, 80 and over, Genetic Markers, Male, Adolescent, Base Sequence, Histocompatibility Antigens Class I, Molecular Sequence Data, Histocompatibility Antigens Class II, DNA, HLA-DR Antigens, DNA Probes, HLA, Middle Aged, Graves Disease, Gene Frequency, Italy, HLA Antigens, HLA-DQ Antigens, Humans, Female, Alleles, Aged
Abstract

HLA Class I and Class II antigens were studied in 103 unrelated Sardinian patients with Graves' disease (GD), 71 of whom had ophthalmopathy, and in 220 healthy controls. Molecular typing of the DQB1 allelic variants was carried out on 34 GD patients and 35 healthy controls, selected for the HLA-DR2-DQw1 phenotype. The results of the serological typing showed a positive association with the DR2 and the DQw1 antigens and a negative association with DR3 and DQw2 antigens. These associations were stronger in the GD patients with ophthalmopathy. The DQB1 molecular analysis in patients with the HLA-DR2-DQw1 phenotype revealed the presence of the DQB1*0502 allele in 91.1 per cent of the patients and in 82.2 per cent of the controls. In the Sardinian population GD seems to present a different HLA association than that observed in other Caucasian populations (DR3-Dw24). The DR2 and DQw1 positive associations may be explained by the high frequency of the DQB1*0502 allelic variant (37.7 per cent) which is rare in the other Caucasian populations. The absence of an association between DR3 and GD in Sardinia can be attributed to the very low frequency of the HLA-B8-DR3 (Dw24) haplotype. In fact, in the Sardinian population, DR3 is associated with the allelic variant Dw25 carried by the HLA-B18-DR3 haplotype.

Published
1991

85. Distribution of killer cell immunoglobulin-like receptors genes in the Italian Caucasian population

Author

Bontadini, A, primary, Testi, M, additional, Cuccia, MC, additional, Martinetti, M, additional, Carcassi, C, additional, Chiesa, A, additional, Cosentini, E, additional, Dametto, E, additional, Frison, S, additional, Iannone, AM, additional, Lombardo, C, additional, Malagoli, A, additional, Mariani, M, additional, Mariotti, L, additional, Mascaretti, L, additional, Mele, L, additional, Miotti, V, additional, Nesci, S, additional, Ozzella, G, additional, Piancatelli, D, additional, Romeo, G, additional, Tagliaferri, C, additional, Vatta, S, additional, Andreani, M, additional, and Conte, R, additional

Published
2006
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90. Role of HLA extended haplotypes in unrelated bone marrow transplantation

Author

La Nasa, G., Vacca, A., Pizzati, A., Ledda, A., Arras, M., Locatelli, Franco, Carcassi, C., Mulargia, M., Piras, E., Floris, R., Mantovani, D., Contu, L., Locatelli F. (ORCID:0000-0002-7976-3654), La Nasa, G., Vacca, A., Pizzati, A., Ledda, A., Arras, M., Locatelli, Franco, Carcassi, C., Mulargia, M., Piras, E., Floris, R., Mantovani, D., Contu, L., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

N/A

Published
1997

93. Implication of HLA-DMA Alleles in Corsican IDDM

Author

Cucchi-Mouillot, P., primary, Lai, S., additional, Carcassi, C., additional, Sorba, P., additional, Stuart-Simoni, M., additional, Amoros, J.-P., additional, Genetet, B., additional, Haras, D., additional, and Contu, L., additional

Published
1998
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95. HLA-B35 alleles in 440 individuals from 16 different populations as assessed by DNA typing

Author

Satz, ML, primary, Theiler, GC, additional, Barrionuevo, P, additional, Schettini, J, additional, Vilches, C, additional, Betuel, H, additional, Gebuhrer, L, additional, Brautbar, C, additional, Papasteriades, C, additional, Carcassi, C, additional, Scorza, R, additional, Moraes, JR, additional, Moraes, ME, additional, Gorodezky, C, additional, Fainboim, L, additional, Stastny, P, additional, and Fernández-Viña, M, additional

Published
1996
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99. A missense mutation in the glucagon receptor gene is associated with non–insulin–dependent diabetes mellitus

Author

Hager, J., primary, Hansen, L., additional, Vaisse, C., additional, Vionnet, N., additional, Philippi, A., additional, Poller, W., additional, Velho, G., additional, Carcassi, C., additional, Contu, L., additional, Julier, C., additional, Cambien, F., additional, Passa, P., additional, Lathrop, M., additional, Kindsvogel, W., additional, Demenais, F., additional, Nishimura, E., additional, and Froguel, P., additional

Published
1995
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