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Earthworms have a prominent role in supporting soil functioning and thus in providing key services to humanity. Their beneficial role relates to effects on soil structure, carbon and nutrient cycling as well as the soil microbial community. Optimizing the role of earthworms in agricultural systems is therefore crucial for maintaining or improving soil quality and supporting a more sustainable, circular agriculture. Here, we summarize established knowledge on the role of earthworms in agronomy; present novel insights from the past decades; and identify key knowledge gaps to be addressed in the future to fully benefit from earthworms in our agricultural soils. We start by discussing how earthworms affect basic soil processes through their effects on soil structure, microbial communities and biogeochemical cycles. Further, we show how as a result of these changes, earthworms indirectly affect plant growth, the soil greenhouse gas balance and play a role in remediation of contaminated arable soils. We further address one of the paradoxes of earthworm ecology: that they are often not present in the soils where they are most needed. We subsequently discuss potential solutions to this paradox. Finally, we identify 10 key questions that need to be addressed in the near future. In our view, recognizing that earthworms are not a stand-alone solution to improving the sustainability of cropping systems, but an essential piece of the puzzle is crucial for optimizing the benefits they offer in agronomic systems. By managing our earthworm populations well, we manage our soils well. [ABSTRACT FROM AUTHOR]

Objective: Plastic bronchitis (PB) is a rare disease characterized by obstruction of the airway by fibrinous mucus plugs. The etiology can be idiopathic or secondary to systematic diseases such as congenital heart diseases. Definitive diagnosis is made by pathological examination of the sputum or bronchial sample taken by bronchoscopy. In this study, the clinical status and treatment status of patients with PB were evaluated. Materials and Methods: Medical records of the patients diagnosed as PB were reviewed retrospectively. Age, gender, clinical symptoms, radiology, bronchoscopic findings, and pathology results were documented. Results: Six patients with PB were included in this study (female:male, 2:4). The median age of the diagnosis was 45 months. The most common symptoms are persistent wet cough and shortness of breath. The duration of symptoms ranged from 30 to 90 days. Atelectasis was the most common radiological finding. Diagnosis was made with pathological examination of the mucus in all patients. All of the patients were treated with bronchoscopic removal of the mucus, and 4 patients required oral prednisolone therapy. Symptoms and radiological findings resolved completely in all patients. Conclusion: Although PB is a rare disease, it should be kept in mind in relation to patients with persistent radiological and clinical respiratory symptoms. [ABSTRACT FROM AUTHOR]

The purpose of the study was to compare the efficacy of 6 different commercially available waterproof cast protectors in their ability to maintain a dry environment and evaluate whether cast protectors perform better than a plastic bag secured with tape in keeping casts dry. We enrolled 23 adult participants to test 6 different commercially available cast protectors and a plastic bag. Participants trialed all cast protectors twice, with and without motion, by fully submerging each cast protector in water with a paper towel held between their index and middle fingers. Moisture accumulation within the cast protectors was estimated by the change in weight of paper towel. An analysis of variance test was performed to compare differences between cast protectors in their ability to maintain a dry internal environment. The plastic bag showed an average moisture accumulation of 5.50 g without motion compared with all other cast protectors, which had 0.0 g of moisture accumulation. One cast protector and the plastic bag had an average moisture accumulation of 0.46 g and 4.51 g with motion compared to all other cast protectors. The plastic bag was ranked the worst by 100% of participants. Cast protectors appear to offer superior protection from moisture compared with a plastic bag. Therapeutic IV. [ABSTRACT FROM AUTHOR]

Given the national goal of "emission peaking and carbon neutralization", China has become the largest country in the world for offshore wind farm construction. At the same time, navigational safety problems in offshore wind farm waters have become increasingly frequent. Owing to the complexity of offshore wind farm waters and the small number of accident data samples available for reference, the system theory method is more suitable for selection than the traditional method. Based on causal analysis based on system theory (CAST) and a complex network (CN), in this study, a qualitative and quantitative accident analysis model, CAST-CN, is constructed to analyze a complete case of vessel and wind turbine allision in offshore wind farm waters. The results show that, at the micro level, in addition to the master, crew, shipping company, and typhoon Hato, the maritime safety administration and the wind farm operation management department have a certain impact on the development of the accident discussed in this study. At the macro level, internal and external factors leading to the lack of system safety are identified, and measures and suggestions for system safety improvement are proposed based on analysis. This study can fill the research gap in the systematic analysis of traffic accidents in offshore wind farm waters and provide support for the safety assessment and decision-making of government management departments and research institutes. [ABSTRACT FROM AUTHOR]

In this study, Ti-48Al-3Nb-1.5Ta powders were manufactured from cast bars by the supreme-speed plasma rotating electrode process (SS-PREP) and used to prepare hot isostatically pressed (HIPed) material at 1050–1260 °C with 150 MPa for 4 h. The phase, microstructure and mechanical performance were analyzed by XRD, SEM, electrical universal material testing machine and other methods. The results revealed that the phase constitution changed from γ phase to α2 phase and then to γ phase with the material changing from as-cast to powders and then to as-HIPed. Compared with the as-cast material, the grain size and element segregation were significantly reduced for both powders and as-HIPed. When the hot isostatic pressing (HIP) temperature was low, the genetic characteristics of the powder microstructure were evident. With the HIP temperature increasing, the homogeneity of the composition and microstructure increased, and the prior particle boundaries (PPBs) gradually disappeared. The elastic moduli of powder and as-HIPed were superior to those of as-cast, which increased with the HIP temperature increasing. The hardness of as-HIPed was lower than that of the powder. The compressive strength, compressive strain, bending strength, and tensile strength of as-HIPed were higher than those of as-cast. With an increase in the HIP temperature, the compressive strength decreased gradually, and the compressive strain first decreased and then increased. [ABSTRACT FROM AUTHOR]

This study discusses the Dramaturgy lecture process using a direct acting practice approach in a theater performance project where the city is positioned as object material, then interpreted and articulated by students through the process of creating theatrical performances. The creation process went through collaborative learning from research on cities, script writing, to creation of works, while Dramaturgy is placed as a theoretical approach in theater creation. This research is an effort to provide empirical experience to students in creating teamwork as a basis for film and television work patterns. This study uses a participatory action research method where the author is involved in all actions taken by film and television (FTV) students. This study found that through project: 1) students gain an understanding of dramaturgy as a science of analyzing drama with all kinds of derivatives related to it, 2) it is more effective to gain empirical experience as a real provision when creating film and Television works, 3) students can create works based on real cases. This research is expected to be able to strengthen KBK in FTV study program and become a treasure trove of intellectual property particularly in Universitas Pendidikan Indonesia and generally become a strategy for developing dramaturgy learning for Indonesia Society

Objectives: Distal forearm fractures are the most common pediatric fractures. This study aimed to investigate the effectiveness of below-elbow cast treatment for displaced distal forearm fractures in children compared to above-elbow cast through meta-analysis of randomized controlled trials. Methods: Several databases from January 1, 2000 until October 1, 2021 were searched for randomized controlled trials that assessed below versus above-elbow cast treatment of displaced distal forearm fractures in pediatric patients. The main meta-analysis comparison was based on the relative risk of loss of fracture reduction between children undergoing below versus above-elbow cast treatment. Other outcome measures including re-manipulation and cast-related complications were also investigated. Results: Nine studies were eligible of the 156 articles identified, with a total of 1049 children. Analysis was undertaken for all included studies with a sensitivity analysis conducted for studies with high quality. In the sensitivity analysis, the relative risks of loss of fracture reduction (relative risk = 0.6, 95% confidence interval = 0.38, 0.96) and re-manipulation (relative risk = 0.3, 95% confidence interval = 0.19, 0.48) between the below and above-elbow cast groups were in favor of below-elbow cast and statistically significant. Cast-related complications were in favor of below-elbow cast but did not attain statistical significance (relative risk = 0.45, 95% confidence interval = 0.05, 3.99). Loss of fracture reduction was noted in 28.9% of patients treated with above-elbow cast and 21.5% in below-elbow cast. Re-manipulation was attempted in 48.1% versus 53.8% of children who lost fracture reduction in the below-elbow cast and above-elbow cast groups, respectively. Conclusion: Below-elbow cast treatment was favored, with statistical significance, in terms of loss of fracture reduction and re-manipulation, and was not associated with a higher risk of cast-related complications. The accumulative evidence currently does not support above-elbow cast treatment and below-elbow cast treatment should be the mainstay for displaced distal forearm fractures in children. Level of evidence: Level I, meta-analysis of therapeutic level I studies. [ABSTRACT FROM AUTHOR]

The cytomatrix at the active zone-associated structural protein (CAST) and its homologue, named ELKS, being rich in glutamate (E), leucine (L), lysine (K), and serine (S), belong to a family of proteins that organize presynaptic active zones at nerve terminals. These proteins interact with other active zone proteins, including RIMs, Munc13s, Bassoon, and the β subunit of Ca2+ channels, and have various roles in neurotransmitter release. A previous study showed that depletion of CAST/ELKS in the retina causes morphological changes and functional impairment of this structure. In this study, we investigated the roles of CAST and ELKS in ectopic synapse localization. We found that the involvement of these proteins in ribbon synapse distribution is complex. Unexpectedly, CAST and ELKS, in photoreceptors or in horizontal cells, did not play a major role in ribbon synapse ectopic localization. However, depletion of CAST and ELKS in the mature retina resulted in degeneration of the photoreceptors. These findings suggest that CAST and ELKS play critical roles in maintaining neural signal transduction in the retina, but the regulation of photoreceptor triad synapse distribution is not solely dependent on their actions within photoreceptors and horizontal cells. [ABSTRACT FROM AUTHOR]

Air transport is considered to be the safest means of transport. However, if an accident occurs, it often ends in catastrophe. Thus, significant efforts have been paid to sustain successful operations in aviation. Several studies have been carried out to understand the underlying reasons for accidents. This study used Fault Tree Analysis (FTA), Failure Mode and Effects Analysis (FMEA) and Causal Analysis based on Systems Theory (CAST) methods to analyse Tenerife aircraft accident and to compare the findings of different methods. The findings showed that while all three methods provided some overlapping findings, the CAST method led to the identification of all causes that were identified by other methods. Considering the nature of the causal factors, FMEA provided more causal factors that are related to organisation and technology than FTA. This study indicates that CAST has a significant value to identify all causes that can be identified by the use of traditional methods. [ABSTRACT FROM AUTHOR]

Background: The present study aimed to determine relationship between psychological distress with self-rated oral health and dental caries status among dental patients. Materials and methods: A cross-sectional study was designed to explore the relationship between psychological distress using Kessler Psychological Distress (K6) Scale with self-rated oral health and dental caries among dental patients in Hyderabad city. Clinical examination was done using Caries Assessment Spectrum and Treatment (CAST) index. P

Borides with varied morphologies and structures obtained by changing B content in as-cast Ti-45Al-2Mn-2Nb alloys are investigated. With the increase of B content, morphologies of borides change from curved to straight, and flake shape, ribbon shape, needle/rod shape, and blocky appear in turn. Curved boride particles have a lamellar structure composed of TiB2 and B2 layers, accompanied by the random appearance and distribution of Ti3B4 and Bf-TiB layers. Except for the absence of the B2 layer, straight needle-like and blocky boride particles have roughly the same structure as curved boride particles, revealing that the formation of curved boride particles is accompanied by divorced eutectic with the matrix and internal irregular eutectic, while no eutectics occurs in straight boride particles. The lack of B atoms during solidification in alloys with lower B content results in a less regular structure and higher stacking fault density of curved boride particles compared to straight boride particles in alloys with higher B content. In addition, some needle-like boride particles are observed to have pure B27-TiB structure without intergrowth. The difference in morphologies and structures can be attributed to the difference in formation mechanism and crystallographic structures of the borides.

In the healthcare system, lower leg fractures remain relevant, incurring costs related to surgical treatment, hospitalization, and rehabilitation. The duration of treatment may vary depending on the individual case and its severity. Casting as a post-surgical fracture treatment is a common method in human and experimental veterinary medicine. Despite the high importance of sheep in preclinical testing materials for osteosynthesis, there is no standardised cast system ensuring proper stabilisation and functionality of hind limbs during the healing of tibia fractures or defects. Existing treatment approaches for tibial osteosynthesis in laboratory animal science include sling hanging, external fixators, or former Achilles tendon incision. These methods restrict animal movement for 4–6 weeks, limit species-typical behaviour, and impact social interactions. Our pilot study introduces a Standardised Walking Cast (SWC) for sheep, enabling immediate physiological movement post surgery. Seven Rhone sheep (female, 63.5 kg ± 6.45 kg) each with a single tibia defect (6 mm mechanical drilled defect) underwent SWC application for 4 weeks after plate osteosynthesis. The animals bore weight on their operated leg from day one, exhibiting slight lameness (grade 1–2 out of 5). Individual step lengths showed good uniformity (average deviation: 0.89 cm). Group housing successfully started on day three after surgery. Weekly X-rays and cast changes ensured proper placement, depicting the healing process. This study demonstrates the feasibility of using an SWC for up to 72 kg of body weight without sling hanging via ceiling mounting or external fixation techniques. Allowing species-typical movement and social behaviour can significantly improve the physiological behaviour of sheep in experiments, contributing to refinement.

Copyright of Ordnance Industry Automation is the property of Editorial Board for Ordnance Industry Automation and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This paper gives a full description of development of foreign air-to-air missiles in 2021. It pre-sents the latest advancement of American AIM-9X, AIM-120, Longshot projects, innovative air-to-air missile technologies, European ASRAAM, IRIS-T, FCAAM, MICA NG, Meteor, Russian Izdeliye 300M, Israeli Python-5 and I-Derby ER, Indian Astra. In the end, the paper summarizes the new development features of air-to-air missiles.

Cast stainless steels with high strength and toughness are very important for industrial production, but the strengthening methods are very limited. In this study, a novel cast multi-phase stainless steel (CMPSS) containing ferrite, martensite and austenite was prepared and its strengthening mechanism was investigated. After solid solution and tempering at 520 °C for 4 h, the yield strength of the sample reaches over 800 MPa, and the total elongation exceeds 13%. This tempering strengthening is mainly achieved by precipitation of the nanoscale Laves phase pinning dislocations in ferrite. However, when prolonging the tempering time or increasing the tempering temperature, the Laves-phase particles precipitate and coarsen along the phase boundary, which seriously damages the strength and toughness of the sample. In addition, high-temperature tempering also leads to a decrease in retained austenite (RA) content by reducing the amount of C and Mn elements in the lath martensite and promotes the precipitation of the R phase (molybdenum-rich intermetallic compound) in ferrite, which is also detrimental to the mechanical properties of CMPSS.

Introduction: Computed tomography can be used to screen and diagnose the presence of drug-filled packets in the body. We present an unusual computed tomography finding in a suspected body packer. Case summary: A traveller suspected of being a body packer was brought to the emergency department complaining of low back pain. On examination, there was an abdominal cast circumferentially encasing his abdomen, which he alleged was part of the management of his lower back pain in his own country. Images: A plain computed tomogram of the abdomen and pelvis revealed that the cast was made of materials with a nodular appearance and heterogeneous density, which was different from that of a plaster of Paris cast. An investigation later confirmed the cast contained cocaine. Conclusion: Our case demonstrates how a body packer can traffic drugs outside their body for an alleged medical reason. [ABSTRACT FROM AUTHOR]

U-Zr metallic fuel is a promising fuel candidate for Gen Ⅳ fast spectrum reactors. Previous experimental irradiation campaigns showed that the sodium thermal bonded U-10Zr fuel design can achieve a burnup of 10% fissions per initial heavy metal atom (FIMA). Advanced metallic fuel designs are pushing the burnup limit to 20% or even 30% FIMA. To achieve the higher burnup and eliminate the pyrophoric sodium, a prototypical annular fuel has been designed, fabricated, clad with HT-9 in the Materials and Fuels Complex, and irradiated in the Advanced Test Reactors of Idaho National Laboratory (INL) to a peak burnup of 3.3% FIMA. During irradiation, the mechanical contact between fuel and cladding acts as a thermal bond. The irradiation lasted for 132 days in the reactor. Recently, the archived fresh and irradiated fuel samples were characterized using advanced characterization capabilities in the Irradiated Materials Characterization Laboratory (IMCL) of INL. This article summarizes the results of advanced characterization and computer vision-based materials informatics to reveal the irradiation effects on U-Zr metallic fuel. Future work will focus on further implementation of advanced characterization and statistical data mining to improve the fidelity of fuel performance modeling and support U-Zr metallic fuel qualification for fast spectrum reactors.

Background: The current study aims to investigate the clinical efficacy of closed reduction and cast immobilization for patients with developmental dysplasia of the hip (DDH) who failed Pavlik harness treatment. Methods: Patients with DDH who underwent cast immobilization under general anaesthesia after the failure of the Pavlik harness or Tübingen brace treatment between January 2015 and December 2020 were retrospectively recruited. General information, including Graf classification of initial diagnosis, initial treatment, age of cast immobilization, IHDI classification, AI index, avascular necrosis (AVN), and residual dysplasia, was collected. The incidence of AVN and late acetabular dysplasia (LACD) was also estimated. Moreover, factors related to AVN and LACD were investigated by multiple logistic regression analysis. Results: Thirty‐four patients (47 hips) were finally included in the current study. Of these patients, 31 hips (66.0%) were successfully treated with closed reduction and cast immobilization. Open reduction was successfully performed in 16 hips (34.0%). Till the latest follow‐up, LACD and AVN were found in 13 (27.7%) and 10 (21.3%) hips, respectively. In the open reduction group, type III and IV of the IHDI classification and type IV of the Ultrasound Graf classification were significantly higher when compared with the closed reduction group. Multiple logistic regression showed that failure of closed reduction was related to the initial types of the Ultrasound Graf and IHDI classifications. Conclusions: Although the success rate of closed reduction after early harness failure in DDH is only 66%, we still advocate closed reduction as a first‐line treatment for children who have failed sling treatment. Even if closed reduction fails, open reduction can still achieve acceptable results. [ABSTRACT FROM AUTHOR]

Studies have reported a high percentage of ankle fracture dislocations with secondary loss of reduction during primary treatment with a splint or cast. This study aimed to assess the rate of secondary loss of reduction in unimalleolar ankle fracture dislocations treated primarily with a cast or external fixator, identify the potential influence of fracture morphology, and investigate the potential implications. Unimalleolar ankle fracture dislocations with and without posterior malleolar fracture between 2011 and 2020 were included. Patients were categorized into two groups, depending on the method of temporary treatment. Fracture morphology, time to definitive surgery, and soft-tissue complications were compared. Of 102 patients, loss of reduction tended to occur more often in the cast group (17.3%) than in the external fixator group (6.0%). The presence of a posterior malleolar fracture did not have a significant influence on loss of reduction in cast immobilization; however, the fragment proved to be significantly bigger in cases with loss of reduction. No statistically significant differences in soft tissue complications or time to definitive surgery were found. Surgeons should consider the application of interval external fixation in the primary treatment of unimalleolar ankle fracture dislocations with additional posterior malleolar fractures. [ABSTRACT FROM AUTHOR]

A complete ostrich femur from the Late Pleistocene deposits of the Upper Cave at Zhoukoudian (China) was referred by Shaw to Struthio anderssoni in the 1930s, but its present whereabouts are unknown. A good quality plaster cast of the missing specimen has been found in the collections of the Natural History Museum (London). This cast provides interesting information about the morphology of this large ostrich femur, which had previously been only summarily described and not illustrated. Although smaller than the femora of the Early Pleistocene giant ostrich Pachystruthio, the robust femur from Zhoukoudian shows morphological similarities with them, and it is suggested that 'Struthio' anderssoni should be placed in the genus Pachystruthio. The importance of old palaeontological casts is emphasized, as well as the need to preserve and curate them properly. [ABSTRACT FROM AUTHOR]

The best choice of orthosis in the treatment of acute Achilles tendon rupture is still under debate. To investigate if choice of orthosis in the first 3 weeks of treatment affected patient reported outcome (Achilles tendon Total Rupture Score (ATRS)), tendon elongation (Achilles Tendon Resting Angle (ATRA) and Heel Rise Height (HRH)) and re-rupture. Registry study in the Danish Achilles tendon Database. Patients treated with cast and patients treated with walker in the first 3 weeks of treatment were compared using a linear mixed-effects model adjusted for potential confounders. 1304 patients were included in the study. No clinically relevant difference was found: Adjusted mean difference (using walker the whole period as reference)(95% CI) ATRS after 1 year = 0.1(−3.0; 4.1), ATRS after 6 months = 2.0(−4.5; 5.8), ATRS after 2 years = 3.0(−0.7; 7.0), HRH difference = 0.6(−6.6; 8.2), ATRA difference = 0.03°(−1.5; 1.6), re-rupture(odds ratio) = 0.812(0.4; 1.61). Patients treated with cast the first 3 weeks after acute Achilles tendon rupture did not have better treatment outcome than patients treated with walker. [ABSTRACT FROM AUTHOR]

Bi-films are double-layered oxide films entrapped in the casting parts. Characterization of such nano-sized defects has always been an engrossing issue. The oxide/Metal/Oxide (OMO) sandwich method provides a physical simulation of oxide layers with areas thin enough to be studied by High-Resolution Transmission Electron Microscopy (HRTEM). The effect of Be on the oxide composition on the surface of Al–5Mg melt was studied with the addition of 2000 ppm Be via OMO technique. The average thickness of the oxide films was measured to be 51.4 and 10 nm for Al–5Mg and Al–5Mg–Be samples, respectively. After EDS and XRD Investigations, the study was carried on with HRTEM equipped with Selective Area Electron Diffraction (SAED). OMO sandwich samples were susceptible to providing areas thin enough to be studied by HRTEM, with no need for sample preparation. While thermodynamics predicts the formation of MgO, BeO, MgAl2O4, BeAl2O4, and Al2O3 oxides, SAED patterns only confirmed the formation of polycrystalline MgO and BeO layer in Be containing alloy. [ABSTRACT FROM AUTHOR]

Copyright of Pós: Revista do Programa de POS-Graduacao Em Artes - EBA/UFMG is the property of Pos - Programa de Pos-graduacao em Artes (PPG-Artes) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aims: To compare the cost-utility of removable brace compared with cast in the management of adult patients with ankle fracture. Methods: A within-trial economic evaluation conducted from the UK NHS and personnel social services (PSS) perspective. Health resources and quality-of-life data were collected as part of the Ankle Injury Rehabilitation (AIR) multicentre, randomized controlled trial over a 12-month period using trial case report forms and patient-completed questionnaires. Cost-utility analysis was estimated in terms of the incremental cost per quality adjusted life year (QALY) gained. Estimate uncertainty was explored by bootstrapping, visualized on the incremental cost-effectiveness ratio plane. Net monetary benefit and probability of cost-effectiveness were evaluated at a range of willingness-to-pay thresholds and visualized graphically. Results: The incremental cost and QALYs of using brace over a 12-month period were £46.73 (95% confidence interval (CI) £-9 to £147) and 0.0141 (95% CI -0.005 to 0.033), respectively. The cost per QALY gained was £3,318. The probability of brace being cost-effective at a £30,000 per QALY willingness-to-pay threshold was 88%. The results remained robust to a range of sensitivity analyses. Conclusion: This within-trial economic evaluation found that it is probable that using a removable brace provides good value to the NHS when compared to cast, in the management of adults with ankle fracture. Cite this article: Bone Jt Open 2022;3(6):455–462.

Abstract Background Dental Caries affect more than half of children and adolescents globally and more so in Africa. Most caries studies in Africa are based on DMFT index which does not assess early carious lesions making early prevention and minimal invasive treatment impossible. This study therefore aimed at determining pattern, socio-demographic and behavioral correlates of dental caries according to Caries Assessment and Treatment Spectrum (CAST). Methods Cross-sectional study involving secondary school adolescents in Copperbelt province, Zambia. Socio-demographics and oral health related behaviors were assessed using a structured questionnaire while dental caries was assessed using CAST. Data were summarized as frequency distributions while cross-tabulation with Chi-squire test and adjusted multinomial logistic regression assessed strength and direction of relationship between socio-demographics, oral health behaviors and dental caries. Level of statistical significance was set at 5%. Results A total of 1,794 participants were enrolled 54% being females. Total frequency of adolescents with healthy teeth (CAST0-2) was 51.1%, pre-morbidity stages (CAST 3–4) was 24.7%, severe morbidity CAST (6–7) was 6.4% and mortality was 2.7%. The odds of being found with teeth at pre-morbidity stage decreased among male OR (95%CI) = 0.55 (0.44, 0.70) and younger participants OR (95%CI) = 0.77 (0.61, 0.98). Participants in high socio-economic status had lower odds of morbidity OR (95%CI) = 0.69 (0.52, 0.92) while those taking sugary foods five times or more per day had higher odds of morbidity OR (95%CI = 1.52 (1.01, 2.34). The odds of being found at mortality clinical stage of caries was lower among males OR (95% CI) = 0.53 (0.29, 0.96) and those who did not attend to a dentist in the previous year OR (95%CI) = 0.42 (0.23, 0.75), while higher odds OR (95%CI = 2.01 (1.02, 3.97) were among the high socio-economic status. Conclusions The proportion of participants with teeth at pre-morbidity and morbidity were high. Socio-demographics and behavioral predictors of dental caries were sex, socio-economic status, frequency of sugary food intake per day and dental visit in the previous year.

[Display omitted] Anatomical 3D-printed nasal casts are valuable models to investigate intranasal drug deposition, providing preclinical data that cannot be obtained in animal models. However, these models are limited since they are often derived from a single patient or represent a mean of several groups. The present study aimed to better characterize the anatomical differences of the nasal cavity in a European sub-population and to assess the potential impact of anatomical variations on intranasal deposition by medical devices. Ninety-eight cranial computed tomography scans of patients were selected and analyzed in 2D and 3D conformations. They showed symmetry of cavities and a high level of heterogeneity of measurements, especially volume and area, in the population. Three anatomical groups with distinct nasal geometry were identified and 3D nasal casts of the most representative patient of each group were printed. Fluorescein was administered using three medical devices: a nasal spray, a sonic jet nebulizer and a prototype mesh-nebulizer. The deposition profiles were compared with the Aeronose® as a reference. Our results show that anatomical variations influenced the deposition profiles depending on the device, with a higher variation with spray and the mesh-nebulizer. This work emphasises the importance of anatomical parameters on drug intranasal deposition and the need to evaluate inhaled drugs on different 3D nasal casts reflecting the target population. [ABSTRACT FROM AUTHOR]

Earthworms are pivotal in shaping soil ecological processes through their bioturbation activity and organic matter consumption. Earthworm species are known to have different impacts on soil structure, but only a small number of species have been studied so far, and few studies have examined how earthworms simultaneously affect soil functions. Here, we measured the impact of different earthworm species on soil structure (bioturbation function), carbon (C) and nitrogen (N) dynamics and the microbial community (organic matter transformation function), while exploring the links between these functions, across distinct soil compartments (surface casts, below-ground drilosphere, and bulk soil). Six earthworm species (Lumbricus terrestris , Allolobophora chlorotica , Octolasion cyaneum, Octodrilus complanatus , Aporrectodea caliginosa meridionalis and Microscolex dubius) of different ecological categories and functional groups were incubated in soil cores with soil and alfalfa litter for 6 weeks. Our results on the bioturbation function illustrated a great diversity of behaviors and confirmed the relevance of a functional classification based on bioturbation metrics. The main microbial hotspots were surface casts, whose characteristics allowed to distinguish two groups of species. Octod. complanatus, L. terrestris and M. dubius induced high humidity (respectively, +57, +48, +74%), high C (respectively, 19.9, 24.8, 33.2 g kg⁻1 dry soil) and N (respectively, 2, 2.3, 3.2 g kg⁻1 dry soil) content and microbial community selection, promoting C and N mineralization. The three other species had a lower impact. The below-ground drilosphere only showed specific characteristics in the case of L. terrestris. The effects of the studied species on the organic matter transformation function did not align with their bioturbation activities nor with their ecological category. These findings show that the contribution of earthworms to C and N turnover is only partially dependent on their bioturbation effects and suggest the usefulness of developing distinct functional groups based on the specific soil functions under consideration. [Display omitted] • Earthworm effects on organic matter and bioturbation functions did not align. • Surface casts were the main microbial hotspots compared to below-ground drilosphere. • Microscolex dubius showed weak bioturbation but strong effects on C and N. • Only Lumbricus terrestris modified its below-ground drilosphere. [ABSTRACT FROM AUTHOR]

There are lots of gene editing tools for targeting genome sequences. Some are almost known, and most are a complete mystery and undiscovered. CRISPR/Cas editing tools have brought about a major revolution in medicine. Researchers have shown that CRISPR can modify DNA much more accurately, economically and easily than previous methods. CRISPR has proven itself effective for the deletion, replacement and insertion of DNA fragments into cell types, tissues and organisms. Recently, combining CRISPR/Cas with factors (transcription factors/repressors, exonucleases, endonucleases, transposons, caspase, fluorescent proteins, oxidoreductive enzymes, DNA/RNA polymerases), and elements (aptamers, barcodes, fluorescent probes, Trigger) have provided genome, transcriptome, proteome and epigenome modification. These modules are being investigated for cancer prevention and therapy and this review focuses on such innovative combinations that hopefully will become a clinical reality in the near future. [ABSTRACT FROM AUTHOR]

Heterogeneous W-steel joining components will produce brittle intermetallic compounds (IMCs) and significant residual stress in the interface. Adding a Cu interlayer serves as an effective solution. Nevertheless, the strengthening of W-Cu-steel joints is restricted because W-Cu and Cu-steel are members of binary immiscible and finite solid solution systems. Thus, accomplishing interface alloying by overcoming the positive generating energy of insoluble systems and opening up interatomic diffusion channels is a crucial issue to be addressed. In this work, casting and brazing technologies were incorporated into bonding W-Cu-steel to provide a high temperature field, as well as the dissolving and wetting of Cu-based liquid phase to refractory W. It is shown that the superior tensile strength of the W/Cu castings-steel brazed joints (∼264 MPa) was achieved, and the joint survived 1000 cycles of thermal fatigue under 1 MW/m2. To assess the effects of brazing and casting on the W-Cu-steel joint, a detailed analysis was conducted on the mechanism of atomic diffusion in the joint interface. It is considered that in W-Cu joining, casting provided a higher thermodynamic driving force than brazing, thus achieving better interatomic diffusion and a wider microalloying region. Cu-steel joining achieved good alloying and forming dendritic extensions by intergranular diffusion. Based on the process optimization results, the feasibility of preparing the U-shaped first wall (FW) mock-up with W armor using brazing technology was verified. This study provides a new technological path, offering a major design and manufacturing guide for plasma facing components (PFCs). [Display omitted] • The novel W/Cu castings-steel and W-Cu interlayer-steel brazed joints are devised by Cu-Ge fillers. • Interdiffusion and microalloying at the W-Cu interface achieved via high temperature induced interface alloying. • Intergranular diffusion and the ferrite phase zone of low deformation were produced in the Cu-steel interface. • The joint exhibited superior tensile performance (264 MPa) and successfully withstood 1000 high heat flux tests of 1 MW/m2. • Validating the feasibility of U-shaped W-coated First Walls with R-angles through brazing first. [ABSTRACT FROM AUTHOR]

The importance of earthworms for soil functioning is widely accepted and is mainly linked to their burrowing, feeding and casting behaviours. However, our knowledge of earthworm behavior is still limited by the lack of efficient and easy-to-use methods. In this work, we describe and test a new marker of earthworm bioturbation. Dense particles of tungsten, visible in X-ray images, were located at a certain depth in repacked soil cores inoculated by either Lumbricus terrestris or Aporrectodea caliginosa , alone or in combination. This marker was compared to the classical luminophore method (i.e. colored sand particles) generally used in aquatic ecology. The dynamics of both the burrow systems and the casting activities was followed using X-ray tomography every two weeks for a period of 10 weeks. Below ground casting activities could be assessed since parts of the casts excreted by the earthworms were marked by tungsten and appeared white in the images. The time dynamics of both burrow and cast productions were almost linear and significantly influenced by the earthworm species and the presence of litter. As expected, L. terrestris created larger (up to 50 cm3) and deeper burrow systems and made fewer macropores compared to A. caliginosa. Surprisingly, both species were equally influenced by the presence of litter, and this highlighted their behavioral plasticity. For example, A. caliginosa decreased by 32 % the volume of burrows in the presence of litter and the resulting burrow system was significantly shallower which showed that this endogeic species is indeed able to partly feed on surface litter. The use of tungsten particles is a promising new tool to accurately characterize the casting activities of earthworms in the soil and to study behavioral plasticity under the influence of environmental factors. • Tungsten (W) particles were tested s a new bioturbation marker visible in X-ray. • When W mixed with soil is egested by earthworms, casts appeared white in X-ray images. • W had no short-term toxicity for Lumbricus terrestris or Aporrectodea caliginosa. • Litter presence at the soil surface influences bioturbation dynamics for both species. [ABSTRACT FROM AUTHOR]

The addition of TiC nanoparticles induced a refined basket-weave structure, replacing coarse α colonies in cast Ti-2.5Al. Thus, the yield strength and elongation of Ti-2.5Al+TiC are increased by 46.3 % and 57.6 %, respectively. The effect of TiC nanoparticles on the grain refinement and tensile properties is more pronounced than the addition of elemental C. [ABSTRACT FROM AUTHOR]

Postmortem evaluation of the human vascular system has a long history, with advancements ranging from dissections to modern imaging techniques like computed tomography (CT scan). This study designs a novel combination of Angiofil, a liquid radiopaque polymer, and latex, a flexible cast material, for cadaveric vascular analysis. The aim was to synergize the advantages of both components, providing accurate radiological images and optimal dissection conditions. Three arterial territories (lateral circumflex femoral artery, profunda brachii artery, and radial artery) were injected and assessed through CT scans and dissections. The Angiofil-latex mixture allowed successful visualization of the vascular networks, offering a simple, reproducible, and non-toxic approach. Quantitative assessments of the three territories, including diameters and lengths, showed comparable results between CT scan and dissection. The technique precision and versatility make it an accessible and valuable tool for anatomical studies, potentially extending its application to MRI analyses. Overall, the Angiofil-latex combination presents a cost-effective solution for researchers, offering enhanced visibility and detailed anatomical insights for various applications, including anatomical variation studies. [Display omitted] • Combination of Angiofil, a radiopaque polymer, and latex, a flexible cast material. • Angiofil-latex mixture provides accurate radiological images. • Angiofil-latex mixture provides optimal dissection conditions. • Angiofil-latex mixture enhances visibility and detailed anatomical insights. [ABSTRACT FROM AUTHOR]

The effects of occupational isocyanate exposure range from asthma and contact dermatitis to neurotoxicity and cancer. Respiratory sensitization due to orthopedic cast application has been well documented. This study aims to compare the safety of standard-of-care fiberglass casts and a novel waterproof cast alternative by measuring the amount of isocyanate released during off-gassing over time. A 3D-printed arm simulator with comparable casing material amounts was placed in a sealed chamber. An isocyanate-sensing color-changing (SafeAir) tag was used to measure the levels of toxic exposure. Triplicate trials were conducted across all time periods (15 min, 1 h, and 24 h) and conditions. The bare arm simulator and freshly opened tags served as negative controls. Normalized pixel intensity indexes and isocyanate release estimates in ppb were derived from ImageJ-analyzed SafeAir tag photos. Fiberglass casts exhibited greater isocyanate release than both the waterproof alternative (p = 0.0002) and no-cast controls (p = 0.0006), particularly at 24 h. The waterproof alternative and no-cast control did not statistically differ (p = 0.1603). Therefore, the waterproof alternative released less isocyanate than the fiberglass casts. Waterproof cast alternatives may be safer than fiberglass by limiting medical professionals’ exposure to toxic isocyanates and, thus, decreasing their risk of suffering occupational asthma.

Context: The widely accepted caries risk assessment tools such as the Cariogram model needs modifications in the scoring of different factors for reliable results. Aims: The study was aimed to report the caries experience in 3-60 years of the Rajasthan population and to apply the newly derived average decayed exfoliated filled teeth/Decayed Missing Filled Teeth (deft/DMFT) scores in the Cariogram model to assess the caries risk. Settings and Design: The cross-sectional study was planned in the Department of Dentistry and a total of 500 participants were equally divided into five groups (3-6, 7-12, 13-30, 31-44, and 45-60 years) were included. Methods and Material: All participants were examined for caries detection using deft/DMFT, ICDAS, and CAST indices according to the predefined protocol. A single examiner evaluated the participants in a dental operatory and data was recorded. Statistical Analysis Used: One-Way ANOVA and Tukey's Post-Hoc tests were used to evaluate the significant difference between the groups of each caries index. Results: A statistically significant difference was observed between the mean deft/DMFT and CAST scores of 3-6, 7-12, and 13-30 age groups with the 45-60 years age group. Caries prevalence was highest (83%) in 31-44 and 45-60 year age groups and lowest (51%) in the 3-6 year age group. Conclusions: Caries experience scores increase as the age increases and the highest scores were observed in 31-44 and 45-60 year age groups and the lowest were observed in the 3-6 year age group. The average ICDAS and CAST scores were higher when compared to the deft/DMFT index.

Background and aimsBoth casts and braces can be used for post-operational immobilization of ankle fractures. This meta-analysis aimed to assess the complications and functional effects of the two types of immobilization.Material and methodsPubMed, Embase, Cochrane, and CNKI was searched for randomized controlled trials (published between Jan 1, 1950, and March 2022). Relative risk (RR) or standard mean difference (SMD) with a 95% confidence interval (CI) was used to present the outcomes. The pooled data were assessed by using the fixed-effects model or random-effects model.ResultsA total of 5 randomized controlled studies involving 930 subjects were included according to our inclusion criteria. On the ankle score at 6w,12w and 52w, there was no statistically significant difference between the two groups. In terms of 6w, the brace group showed better ankle dorsiflexion (MD = 6.78, 95% CI 0.56–13.00, p = 0.03) and plantar flexion (MD = 6.58, 95% CI 1.60–11.55, p = 0.01) than the cast group. The wound complications (RR = 3.49, 95% CI 1.32 to 9.24, p = 0.01) and total complications (RR = 3.54, 95% CI 1.92 to 6.50, p

Introduction; Percutaneous Achilles tenotomy is a standard procedure in most clubfoot patients treated with Ponseti method as the most widely use method of conservative clubfoot treatment. To our knowledge, there are not studies published in Albanian literature about this technique. Our goal is to present results of conservative treatment of idiopathic clubfoot where this technique was performed. Material and Method. This is a prospective study of all idiopathic clubfoot patients treated in our Institution with Ponseti Method. We performed this technique under sedation anesthesia in operation room, not in clinic. We measured age of patient at time of presentation, gravity according to Pirani score, number of casting, need for Achilles tenotomy). We measured the degree of angle of dorsiflexion before and after this procedure, the gravity and need for a second procedure. Results: Out 400 clubfeet treated during 2005-2010 we included in our study 372 case that needed the percutaneous Achilles tenotomy performed. Average age at presentation was 3 weeks. Average Pirani score was 5.5. The number of weekly serial cast needed before the tenotomy was 8. Dorsiflexion angle after this procedure was improved by 45 degree (range from 30 to 90 degree). Only 2 cases needed reoperation due to non-compliance with foot abduction bar and physiotherapy Conclusion: The percutaneous Achilles tenotomy is used in 93% of case with idiopathic clubfoot serie of patient. It is an easy technique performed with sedation anesthesia in operation room not with local anesthesia. Achilles tenotomy is an important element to avoid recurrence This supports other studies that have used this method.

Purpose: Above-knee casts pose a major challenge in the day-to-day activities among walking age clubfoot patients due to complete restriction of knee movement. This current study investigates the effectiveness of below-knee casts compared to above-knee casts for managing walking age clubfoot deformity. Methods: After approval from the institutional ethical committee, we enrolled walking age clubfoot patients for deformity correction through corrective manipulation and casting through below-knee casts over 2 years. The corrective manipulation was performed using the Ponseti technique. The patients were followed for a minimum of 2 years period. To compare the effectiveness of below-knee casts over above-knee casts, we enrolled equal numbers of walking age clubfeet matched for age and gender. We compared the two groups in terms of initial and post-correction Dimeglio scores, individual deformities corrections (maximum ankle dorsiflexion, heel varus correction, foot abduction), failure rates, relapses, and complication rates. Results: 56 patients with 80 clubfeet with a mean follow-up of 39.98 months were considered for the final analysis. There were 29 patients in the below-knee cast group and 27 in the above-knee cast group, with 40 clubfeet each. The patients in the above-knee casting group had significantly better post-correction Dimeglio scores and individual deformity components corrections than the below-knee cast group. There were nil failures in the above-knee casting group and 7.5% in the below-knee cast group. The relapse rate was 15% in both groups, with none requiring any extensive soft tissue procedure. We did not encounter any major complications during the treatment and follow-up. Conclusion: The deformity correction and maintenance are suboptimal with the below-knee casts. Therefore, above-knee casts should be the preferred management modality for correction of walking age clubfoot deformities. [ABSTRACT FROM AUTHOR]

Forearm fractures such as distal radius fractures are traditionally treated with a plaster or synthetic cast. Patients commonly report inconvenience of the cast, skin problems, and occasionally radial sensory nerve numbness. A known issue with casting is that the rate of secondary dislocation is high. As an alternative to casts, personalized 3D-printed braces are increasingly used. This review provides an inventory of current developments and experience with 3D-printed forearm braces. Main focus was on the design requirements, materials used, technical requirements, and preclinical and clinical results. Review of 12 studies showed that all printed braces used an open design. Fused Deposition Modelling is most commonly used 3D-printing technique (seven studies) and polylactic acid is the most commonly used material (five studies). Clinical evaluation was done in six studies, mainly involving distal radius fractures, and generally showed a low complication rate and high patient satisfaction with the printed brace. Whether or not the results obtained with 3D-printed braces are superior to results after casting requires further studies. [ABSTRACT FROM AUTHOR]

Simple Summary: A bibliometric analysis was carried out to know the evolution of research on genes associated with meat tenderness, of interest for the development of selection programs. Since 1993, studies have been limited to a few researchers in high-income countries due to the costs associated with the techniques. The main findings showed that the scientific production had a discontinuous growth because science experienced a significant change since approximately 2010. Marker-assisted selection was widely used, evaluating mainly CAPN (calpain) and CAST (calpastatin) genes for their contribution to meat tenderness, especially in cattle. However, the effects are small; therefore, genomic selection was implemented by genotyping thousands of single nucleotide polymorphisms (SNPs) for further explanation of genetic variation. The results shown are important for scholars to identify emerging methodologies and gaps in the literature and to know who the prolific authors and institutions in the field for possible collaborations, etc., are. Tenderness is one of the main characteristics of meat because it determines its price and acceptability. This is the first bibliometric study on the trend of research on the role of genes in meat tenderness. A total of 175 original and English-language articles published up to 2021 were retrieved from Scopus. The bibliometric analysis was carried out with VOSviewer (version 1.6.18, Eck and Waltman, Leiden, Netherlands) and complemented with the Analyze search results service from Scopus. Erroneous and duplicate data were eliminated, and incomplete information was added to standardize the results. Scientific production was evaluated by means of quantity, quality and structure indicators. As a first glance, 8.816% of authors have published more than 50% of papers mainly related to genes encoding the calpain (CAPN)-calpastatin (CAST) system and single nucleotide polymorphisms (SNPs). Among other findings, a strong link was found between the contribution of the main countries (led by the United States with) and their institutions (led by the USDA Agricultural Research Service with) to their gross domestic product. Most studies on the topic are published in the Journal of Animal Science, and other journals with high impact according to the number of citations and different metrics. Finally, when evaluating the most cited articles, the occurrence and association of the main keywords, it was confirmed that research is focused on the role of CAPN and CAST genes and of SNPs in beef tenderness. The change in science was emphasized; although marker-assisted selection is still used, genes have an infinitesimal effect on complex traits. Therefore, since about 2010, new research groups adopted genomic selection to evaluate dense panels of SNPs and better explain genetic variation in meat tenderness. [ABSTRACT FROM AUTHOR]

Objective: There is limited evidence about the cross-cultural validity of autistic symptoms in schoolaged children in Brazil. We used data from a large school survey to evaluate the factor structure of autism symptoms in community-dwelling children and adolescents. Methods: We translated the Childhood Autism Spectrum Test to Brazilian Portuguese and performed factor analyses to investigate the factor structure of parent-reported autistic symptoms in a large sample (n=8,571) of children/adolescents from a school survey in the metropolitan area of São Paulo. Results: Autistic symptoms were best conceptualized under a correlated-factors model with two factors: one predominantly characterized by social-communication symptoms and the other by symptoms of inflexible/restricted language, behaviors, and interests. Conclusions: These findings provide evidence that the structure of autistic symptoms in Brazil is similar to that described in other countries, indicating the cross-cultural validity of autism in Brazil. [ABSTRACT FROM AUTHOR]

Vehicle emission regulations in Europe and many Asian countries include a particle number limit. The number concentration is measured, typically, with condensation particle counters (CPCs). For research purposes, the size distributions provide useful information. Scanning mobility particle sizers (SMPSs) accurately provide the size distribution but are not suitable for transient aerosol. Engine (fast) exhaust particle sizers (EEPSs) cover this gap, but with less accuracy. Fast size distribution instruments are commonly used in the research and development of engines. In the last few years, instrument algorithms have been improved, but studies assessing the improvements are limited, in particular in their lower size range, around 10–20 nm, and for soot-like aerosol. In this paper, we compared the three instruments using salt, silver, diffusion flame soot (CAST), and spark discharge graphite particles. Moreover, vehicle exhaust number concentration measurements with EEPSs over a seven-year period were presented. In terms of particle concentration, EEPS overestimated, on average, 25% compared to CPC, in agreement with previous studies. Its accuracy for mean particle size determination was better than 5 nm compared to SMPS. The agreement between the instruments was satisfactory but the uncertainty increased at low concentrations and larger particle sizes, showing that there is still room for further improvements. Experimental challenges, such as low concentration levels of modern vehicles, losses in the diluters, use of photometric mode by the CPCs, and the material impact, are also discussed. [ABSTRACT FROM AUTHOR]

The flowability of Ultra-high molecular weight polyethylene (UHMWPE) is very poor so flow modification is needed to improve its processing efficiency, but flow modification could significantly deteriorate its wear resistance. To solve this technical problem, it is necessary to recognize the reasons why flow modifiers deteriorate the wear resistance of UHMWPE. In current research, influence of calcium stearate (CaSt) which is a commonly used flow modifier on the wear resistance of UHMWPE was investigated, the experimental results showed that a small amount of CaSt (0.5wt%) could significantly deteriorate the wear resistance of UHMWPE (11%). Subsequently, the effect of CaSt on the three-phase structure (amorphous, crystalline and interphase) of UHMWPE was investigated to explain why CaSt deteriorates the wear resistance of UHMWPE in terms of structure–property relationship. The study of crystallization and melting behavior indicates that the incorporation of CaSt makes the matrix produce more well-formed crystals thus increasing the hardness of the matrix, and the increase in hardness can alleviate the degree of abrasive wear. The study of the amorphous region found that CaSt has a unique disentanglement effect, which reduces the degree of entanglement of molecular chains of the matrix, and the reduction of the degree of entanglement deteriorates the shear resistance of the matrix, thus aggravating the shear damage of the sample during the wear process. Meanwhile, the disentanglement effect of CaSt can also improve the recrystallization ability of the matrix, reducing the interphase of the matrix thus making the matrix more susceptible to structural damage during the wear process. Furthermore, the incorporation of CaSt significantly reduces the heat resistance of the matrix, which makes the wear resistance of the matrix deteriorate more caused by the friction heat during the wear process. This paper can provide theoretical guidance to solve the problem of severe degradation of wear resistance after flow modification of UHMWPE and provide inspiration for the structural design of other wear-resistant materials. [ABSTRACT FROM AUTHOR]

This paper deals with the topics of violence and enmity both in terms of their traditional and cultural characteristics, as well as in light of the transformations undergone between the 16th and 17th centuries following the measures implemented in various European environments to target above all the alarming phenomenon of banditry, and adopted in consideration of the new-found need for safety and tranquillity. Enmity is typical of all human groups everywhere and at any point in time. And since for long it was often closely related to a distinct dimension of violence, its characteristics and changes reveal the symbolic meanings and values that each society ascribes to conflicts and to the methods of their resolution. In fact, the concept of enmity, deeply intertwined with that of revenge, played an essential role within a society in which a peace-centred order was not only pre-eminent but also constituted as the safeguarding of social hierarchies focused on status, kinship, and honour. In the second half of the 16th century, in the wake of widespread social insecurity and the crisis of political polycentrism that had characterised the mediaeval state, the cultural system of enmity lost its traditional stamp and became, often unawares, a means of extreme violence. This passage is clearly noticeable in the ruthless challenge that the central powers mounted against banditry, enacting a legislation that led to a veritable state of emergency, which among other things entailed an explicit mandate for the use of private violence. [ABSTRACT FROM AUTHOR]