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90 results on '"Bykov, V. V."'

58. Effects on thrombocytic hemostasis of a new derivate indolinone.

Author

Bykov, V. V., Serebrov, V. Yu., Udut, V. V., Udut, E. V., and Fisenko, V. P.

Subjects
*ASPIRIN, *INDOLINONE, *BLOOD platelet aggregation, *PLATELET aggregation inhibitors, *HEMOSTASIS
Abstract

Objective. Specific activity of an antiplatelet drug of indolinone series (codenamed DI) was studied in vitro in a model of ADP-induced platelet aggregation in vitro and in vivo in a model of streptozotocininduced diabetes mellitus in rats. Material and Methods. Acetylsalicylic acid and dipyridamole were used as reference drugs. In vitro tests have demonstrated that DI exhibits antiplatelet activity in a wide range of concentrations (0,75×10-6 - 1.5×10-5 M, P<0,05), being comparable to acetylsalicylic acid and dipyridamole. In vivo tests have demonstrated dose-dependent antiplatelet activity of DI in doses of 2,5 - 20 mg/kg (21-14 %). Results and Discussion.Increasing the dose of DI above 10 mg/kg doesn't increase its antiplatelet activity. After multiple oral administration to rats with streptozotocin-induced diabetes mellitus in 10 mg/kg dose, DI has exhibited antiplatelet activity, reducing the platelet aggregation rate to that of the control group (P<0,05).Conclusion. Thus, DI isapromisingcompound for furtherdevelopmentof an antiplatelet drug with new mechanism of action [ABSTRACT FROM AUTHOR]

Published
2019
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75. Vladimir Alexandrovich Kondratiev on the 70th anniversary of his birth.

Author

Astashova, I. V., Bagirov, L. A., Borovskikh, A. V., Bykov, V. V., Vetokhin, A. N., Goritskii, A. Yu., Grishina, G. V., Denisova, N. V., Il'yashenko, Yu. S., Kapustina, T. O., Kozlov, V. V., Kon'kov, A. A., Matrosov, I. V., Millionschikov, V. N., Nikishin, V. A., Radkevich, E. V., Rosanova, O. S., Rosendorn, E. R., Rozov, N. Kh., and Sadovnichii, V. A.

Subjects
MATHEMATICS, MATHEMATICIANS, DIFFERENTIAL equations, ELLIPTIC functions
Abstract

The article provides an overview of mathematical studies performed by Vladimir Alexandrovich Kondratiev, on the 70th anniversary of his birth. Included are studies on: the oscillation and nonoscillation conditions for solutions of ordinary differential equations; elliptic equations in domains with angular and conical points; and a problem with oblique derivatives.

Published
2007
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78. Present State and Immediate Problems of Short-Term Hydrodynamic Weather Forecasting

Author

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO, Bykov,V. V., Bortnikov,S. A., Kadyshnikov,V. M., Pressman,D. Ya., FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO, Bykov,V. V., Bortnikov,S. A., Kadyshnikov,V. M., and Pressman,D. Ya.

Abstract

Further advancements in the theory and practice of hydrodynamic short-term weather forecasting is illustrated by a brief description of prognostic models and effective work being done in the Hydrometeorological Scientific Research Center, USSR with the aid of the complete hydrodynamics equations., Edited trans. of Trudy v Vsesoyuznogo Meteorologicheskogo Sezda. Seksiya Prognoza Pogody (USSR) v2 p8-18 1972, by Marilyn Olaechea.

Published
1974

80. Digital Modeling in Statistical Radio Engineering

Author

ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA, Bykov,V. V., ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA, and Bykov,V. V.

Abstract

Mathematical methods for modeling processes common in radio systems are developed for use with multi-purpose digital computers. Efficient algorithms are constructed for digital modeling of radio signals and noise as well as a wide range of random processes. The modeling of random vectors and non-stationary and Markov processes are discussed. Models of random process are considered according to distribution law and within the framework of correlation theory. The modeling of signals and noise as they pass through linear and nonlinear systems are well covered. The principal criteria used in evaluating algorithms are accuracy and the efficient use of computer time. Several applications of digital modeling to statistical radio engineering problems are examined., Trans. of mono. Tsifrovoe Modelirovanie v Statisticheskoi Radiotekhnike, Moscow, 1971 328p.

Published
1973

81. Meteorological Translations Number 16

Author

DEPARTMENT OF TRANSPORT TORONTO (ONTARIO) METEOROLOGICAL BRANCH, Kibel,I. A., Bykov,V. V., Kurbatkin,G. P., Gorelysheva,I. V., Beloussov,S. L., DEPARTMENT OF TRANSPORT TORONTO (ONTARIO) METEOROLOGICAL BRANCH, Kibel,I. A., Bykov,V. V., Kurbatkin,G. P., Gorelysheva,I. V., and Beloussov,S. L.

Abstract

Contents: Some new problems of hydrodynamic short-range weather prediction; A multi-level scheme for numerical analysis of upper air data; A method for objective analysis of surface pressure and pressure tendency fields which preserves the field features with a scale of about 100 km5

Published
1970

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