Search

Your search keyword '"Brůža,, Petr"' showing total 56 results
Start Over Author "Brůža,, Petr"
56 results on '"Brůža,, Petr"'

56. Fluorescence-guided and molecularly-guided debridement: identifying devitalized and infected tissue in orthopaedic trauma.

Author

Elliott JT, Henderson E, Streeter SS, Demidov V, Han X, Tang Y, Sottosanti JS, Bateman L, Brůža P, Jiang S, and Gitajn IL

Abstract

Following orthopaedic trauma, bone devitalization is a critical determinant of complications such as infection or nonunion. Intraoperative assessment of bone perfusion has thus far been limited. Furthermore, treatment failure for infected fractures is unreasonably high, owing to the propensity of biofilm to form and become entrenched in poorly vascularized bone. Fluorescence-guided surgery and molecularly-guided surgery could be used to evaluate the viability of bone and soft tissue and detect the presence of planktonic and biofilm-forming bacteria. This proceedings paper discusses the motivation behind developing this technology and our most recent preclinical and clinical results.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results