Search

Your search keyword '"Bontempi, Luca"' showing total 301 results
Start Over Author "Bontempi, Luca"
301 results on '"Bontempi, Luca"'

54. Sinus Node Dysfunction in a Young Patient With COVID-19

Author

Cimino, Giuliana, primary, Pascariello, Greta, additional, Bernardi, Nicola, additional, Calvi, Emiliano, additional, Arabia, Gianmarco, additional, Salghetti, Francesca, additional, Bontempi, Luca, additional, Vizzardi, Enrico, additional, Metra, Marco, additional, and Curnis, Antonio, additional

Published
2020
Full Text
View/download PDF

56. The MB score: a new risk stratification index to predict the need for advanced tools in lead extraction procedures

Author

Bontempi, Luca, primary, Curnis, Antonio, primary, Della Bella, Paolo, primary, Cerini, Manuel, primary, Radinovic, Andrea, primary, Inama, Lorenza, primary, Melillo, Francesco, primary, Salghetti, Francesca, primary, Marzi, Alessandra, primary, Gargaro, Alessio, primary, Giacopelli, Daniele, primary, and Mazzone, Patrizio, primary

Published
2020
Full Text
View/download PDF

57. Left Atrial Thrombus Formation During Pulmonary Vein Cryoablation: The Pivotal Role of Intracardiac Echocardiography.

Author

Bontempi, Luca, Fundaliotis, Angelica, Moretti, Marina, Giacopelli, Daniele, Ghidelli, Francesca, Pitì, Antonino, Curnis, Antonio, and Dell'Aquila, Andrea

Subjects
*THROMBOSIS, *PULMONARY vein abnormalities, *PULMONARY veins, *CRYOSURGERY, *ECHOCARDIOGRAPHY
Abstract

Trans-septal puncture (TSP) is a challenging step in pulmonary vein isolation (PVI) procedure for atrial fibrillation. Fluoroscopy guidance alone is burdened by a high rate of complications. Therefore, additional transesophageal echocardiography or intracardiac echocardiography (ICE) guidance is recommended to reduce the risk of adverse events. We report the case of a PVI procedure using cryoablation complicated by the formation of a serpiginous left atrial swinging thrombus after TSP. This high-risk adverse event was resolved without sequelae using ICE guidance. [ABSTRACT FROM AUTHOR]

Published
2023

60. Combining home monitoring temporal trends from implanted defibrillators and baseline patient risk profile to predict heart failure hospitalizations: results from the SELENE HF study.

Author

D'Onofrio, Antonio, Solimene, Francesco, Calò, Leonardo, Calvi, Valeria, Viscusi, Miguel, Melissano, Donato, Russo, Vitantonio, Rapacciuolo, Antonio, Campana, Andrea, Caravati, Fabrizio, Bonfanti, Paolo, Zanotto, Gabriele, Gronda, Edoardo, Vado, Antonello, Calzolari, Vittorio, Botto, Giovanni Luca, Zecchin, Massimo, Bontempi, Luca, Giacopelli, Daniele, and Gargaro, Alessio

Subjects
HEART failure treatment, RESEARCH, RESEARCH methodology, ARTHRITIS Impact Measurement Scales, IMPLANTABLE cardioverter-defibrillators, EVALUATION research, CARDIAC pacing, COMPARATIVE studies, RANDOMIZED controlled trials, HOSPITAL care, RESEARCH funding, STROKE volume (Cardiac output), HEART failure
Abstract

Aims: We developed and validated an algorithm for prediction of heart failure (HF) hospitalizations using remote monitoring (RM) data transmitted by implanted defibrillators.Methods and Results: The SELENE HF study enrolled 918 patients (median age 69 years, 81% men, median ejection fraction 30%) with cardiac resynchronization therapy (44%), dual-chamber (38%), or single-chamber defibrillators with atrial diagnostics (18%). To develop a predictive algorithm, temporal trends of diurnal and nocturnal heart rates, ventricular extrasystoles, atrial tachyarrhythmia burden, heart rate variability, physical activity, and thoracic impedance obtained by daily automatic RM were combined with a baseline risk-stratifier (Seattle HF Model) into one index. The primary endpoint was the first post-implant adjudicated HF hospitalization. After a median follow-up of 22.5 months since enrolment, patients were randomly allocated to the algorithm derivation group (n = 457; 31 endpoints) or algorithm validation group (n = 461; 29 endpoints). In the derivation group, the index showed a C-statistics of 0.89 [95% confidence interval (CI): 0.83-0.95] with 2.73 odds ratio (CI 1.98-3.78) for first HF hospitalization per unitary increase of index value (P < 0.001). In the validation group, sensitivity of predicting primary endpoint was 65.5% (CI 45.7-82.1%), median alerting time 42 days (interquartile range 21-89), and false (or unexplained) alert rate 0.69 (CI 0.64-0.74) [or 0.63 (CI 0.58-0.68)] per patient-year. Without the baseline risk-stratifier, the sensitivity remained 65.5% and the false/unexplained alert rates increased by ≈10% to 0.76/0.71 per patient-year.Conclusion: With the developed algorithm, two-thirds of first post-implant HF hospitalizations could be predicted timely with only 0.7 false alerts per patient-year. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

61. Antibacterial Envelope to Prevent Cardiac Implantable Device Infection

Author

Tarakji, Khaldoun G, Mittal, Suneet, Kennergren, Charles, Corey, Ralph, Poole, Jeanne E, Schloss, Edward, Gallastegui, Jose, Pickett, Robert A, Evonich, Rudolph, Philippon, François, Mccomb, Janet M, Roark, Steven F, Sorrentino, Denise, Sholevar, Darius, Cronin, Edmond, Berman, Brett, Riggio, David, Biffi, Mauro, Khan, Hafiza, Silver, Marc T, Collier, Jack, Eldadah, Zayd, Wright, David J, Lande, Jeff D, Lexcen, Daniel R, Cheng, Alan, Wilkoff, Bruce L, Edward, Schloss, Jose, Gallastegui, Robert Andrew Drew Pickett, Rudolph, Evonich, François, Philippon, Janet, Mccomb, Steven, Roark, Denise, Sorrentino, Darius, Sholevar, Khaldoun, Tarakji, Edmond, Cronin, Brett, Berman, David, Riggio, Mauro, Biffi, Igor, Diemberger, Hafiza, Khan, Marc, Silver, Jack, Collier, Zayd, Eldadah, David Justin Wright, Joellyn, Moore, Kamel, Addo, R Chris Jones, Robert, Schaller, Joaquin, Martinez-Arraras, Ismaile, Abdalla, Ziad, Issa, Calum, Redpath, Jean, Moubarak, Surinder Kaur Khelea, Berit Thornvig Philbert, Timothy Alexander Simmers, Lucas V, A Boersma, Panagiotis, Korantzopoulos, John, Love, Ralph, Augostini, Havard, Keilegavlen, Svein, Faerestrand, Suneet, Mittal, Scott, Wiggins, Jeff, Healey, Brian, Ramza, Riple, Hansalia, Chad, Brodt, Paul, Wang, Attila, Mihalcz, Daniel, Gras, Ulrika Maria Birgersdotter-Green, Ethan, Fruechte, Douglas, Hodgkin, Daniel, Lustgarten, Gery, Tomassoni, Fozia, Ahmed, Cecilia, Rorsman, Pugazhendhi, Vijayaraman, Judith, Mackall, Harish, Manyam, Allan, Nichols, Serge David Bar-Lev, James, Merrill, Wayne, Adkisson, Juan José Olalla, Nagib, Chalfoun, Eric, Johnson, Jorge, Massare, Camille, Frazier-Mills, John, Chenarides, Mohammad, Jazayeri, Kevin, Boran, John, Schoenhard, Simon, Milstein, John, Bailey, Mark, Kremers, Thomas, Burkart, Wilfried, Mullens, Jay, Franklin, Frederick, Ehlert, Charles, Henrikson, Ilana, Kutinsky, Ignasi, Anguera, Michael, Springer, Grant, Simons, Frederic, Anselme, David, Sandler, Bontempi, Luca, Laurence Marie-Pierre Guedon-Moreau, Sei, Iwai, John, Mcanulty, Eric, Putz, Gregory, Golovchiner, David, Juang, Peter, Ammann, Randy, Jones, Allan, Katz, Malini, Madhavan, Martin, Emert, António Cãndido de Freitas Fernandes Hipólito Reis, Tina, Salo, Christopher, Cole, Stephen, Keim, George, Thomas, Chanta, Chakrabarti, Christina, Murray, Pierce, Vatterott, Robert, Sangrigoli, Theofanie, Mela, Mark John Mason, Robert, Winslow, Shang-Chiun, Lee, Przemyslaw, Mitkowski, Antoine Da Costa, Girish, Nair, Westby, Fisher, Jean-Claude, Deharo, Mark, Castellani, David, Rhine, Hamid, Ghanbari, Gautham, Kalahasty, Daniel, Anderson, Daniel, Frisch, Larry, Chinitz, Charles, Love, Andrew, Rubin, Timothy, Lessmeier, Steven, Compton, Mark, Mitchell, Katherine, Fan, Saeed Bandar Al Ghamdi, Gabriela, Kaliska, Peter, Margitfalvi, Glenn, Meininger, Maria Grazia Bongiorni, Jeffrey, Luebbert, Michael, Pelini, Silvia, Misikova, Jerome, Kuhnlein, Robert, Schweikert, Jean-Manuel, Herzet, Stefano, Pedretti, Byron, Lee, Peter, Santucci, Jonas, Hörnsten, Samir, Saba, Evan, Adelstein, Stuart, Mendenhall, Ngai-Yin, Chan, Shabbar, Jamaly, Javier, Moreno, Tiziano, Moccetti, Paresh, Shah, John Douglas Pappas, Thomas, Blum, Etienne, Pruvot, Anthony, Chu, Chetan, Gangireddy, Joshua, Cooper, Walter, Chien, Ali, Al-Mugamgha, Matthew, Smelley, Heath, Saltzman, Arun, Kolli, William, Kostis, Sluja, Amardeep, Charles, Kennergren, Rajiv, Handa, Emmanuel, Simantirakis, Tony, Simmons, Randel, Smith, Marye, Gleva, George, N Theodorakis, Emad, Aziz, Scott, Burke, Kah Leng Ho, Carlo De Asmundis, Kenneth, Civello, Tan Vern Hsen, Darryl, Wells, Hüseyin, Ince, Sami, Pakarinen, Jodie, Hurwitz, Vinay, Mehta, Imra Zainal Abidin, Michael, Osayamen, Javier, Banchs, Kelly, Kim, Andrzej, Kutarski, João Manuel Frazão, Rodrigues de Sousa, Senthil, Tambidorai, James, Sandberg, Rubén, Aguayo, Darren, Traub, Siddarth, Mukerji, Rajesh, Venaktaraman, Ramesh, Hariharan, Saravanan, Krishinan, Jorge, Silvestre, Vladimir, Rankovic, University of Zurich, and Tarakji, Khaldoun G

Subjects
Male, medicine.medical_specialty, Pacemaker, Artificial, Standard of care, Prosthesis-Related Infections, Heart Diseases, Minocycline, 610 Medicine & health, Kaplan-Meier Estimate, 2700 General Medicine, 030204 cardiovascular system & hematology, 11171 Cardiocentro Ticino, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, Single-Blind Method, 030212 general & internal medicine, Limited evidence, Antibiotic prophylaxis, Intensive care medicine, Aged, business.industry, Incidence, Standard of Care, General Medicine, Bacterial Infections, Middle Aged, Antibiotic Prophylaxis, Defibrillators, Implantable, Anti-Bacterial Agents, Pacemaker, Multicenter study, Artificial, Disease prevention, Female, Implantable, Rifampin, business, Defibrillators
Abstract

Infections after placement of cardiac implantable electronic devices (CIEDs) are associated with substantial morbidity and mortality. There is limited evidence on prophylactic strategies, other than the use of preoperative antibiotics, to prevent such infections.We conducted a randomized, controlled clinical trial to assess the safety and efficacy of an absorbable, antibiotic-eluting envelope in reducing the incidence of infection associated with CIED implantations. Patients who were undergoing a CIED pocket revision, generator replacement, or system upgrade or an initial implantation of a cardiac resynchronization therapy defibrillator were randomly assigned, in a 1:1 ratio, to receive the envelope or not. Standard-of-care strategies to prevent infection were used in all patients. The primary end point was infection resulting in system extraction or revision, long-term antibiotic therapy with infection recurrence, or death, within 12 months after the CIED implantation procedure. The secondary end point for safety was procedure-related or system-related complications within 12 months.A total of 6983 patients underwent randomization: 3495 to the envelope group and 3488 to the control group. The primary end point occurred in 25 patients in the envelope group and 42 patients in the control group (12-month Kaplan-Meier estimated event rate, 0.7% and 1.2%, respectively; hazard ratio, 0.60; 95% confidence interval [CI], 0.36 to 0.98; P = 0.04). The safety end point occurred in 201 patients in the envelope group and 236 patients in the control group (12-month Kaplan-Meier estimated event rate, 6.0% and 6.9%, respectively; hazard ratio, 0.87; 95% CI, 0.72 to 1.06; P0.001 for noninferiority). The mean (±SD) duration of follow-up was 20.7±8.5 months. Major CIED-related infections through the entire follow-up period occurred in 32 patients in the envelope group and 51 patients in the control group (hazard ratio, 0.63; 95% CI, 0.40 to 0.98).Adjunctive use of an antibacterial envelope resulted in a significantly lower incidence of major CIED infections than standard-of-care infection-prevention strategies alone, without a higher incidence of complications. (Funded by Medtronic; WRAP-IT ClinicalTrials.gov number, NCT02277990.).

Published
2019

66. Clinical impact of defibrillation testing in a real‐world S‐ICD population: Data from the ELISIR registry.

Author

Ricciardi, Danilo, Ziacchi, Matteo, Gasperetti, Alessio, Schiavone, Marco, Picarelli, Francesco, Diemberger, Igor, Bontempi, Luca, Di Belardino, Natale, Bisignani, Giovanni, De Bonis, Silvia, Mitacchione, Gianfranco, Calabrese, Vito, Lavalle, Carlo, Piro, Agostino, Pignalberi, Carlo, Santini, Luca, Grigioni, Francesco, Tondo, Claudio, Biffi, Mauro, and Forleo, Giovanni Battista

Subjects
CHI-squared test, FISHER exact test, IMPLANTABLE cardioverter-defibrillators, MEDICAL protocols, SHOCK (Pathology), STATISTICS, DATA analysis software, DESCRIPTIVE statistics, LOG-rank test, MANN Whitney U Test, EQUIPMENT & supplies
Abstract

Background: Current guidelines recommend defibrillation testing (DT) performance in patients with a subcutaneous implantable cardioverter defibrillator (S‐ICD), theoretically to reduce the amount of ineffective shocks. DT, however, has been proven unnecessary in transvenous ICD and real‐world data show a growing trend in avoidance of DT after S‐ICD implantation. Methods: All patients undergoing S‐ICD implant at nine associated Italian centers joining in the ELISIR registry (ClinicalTrials.gov Identifier: NCT04373876) were enrolled and classified upon DT performance. Long‐term follow‐up events were recorded and compared to report the long‐term efficacy and safety of S‐ICD implantations without DT in a real‐world setting. Results: A total of 420 patients (54.0 ± 15.5 years, 80.0% male) were enrolled in the study. A DT was performed in 254 (60.5%) patients (DT+ group), while in 166 (39.5%) was avoided (DT− group). Over a median follow‐up of 19 (11–31) months, a very low rate (0.7%) of ineffective shocks was observed, and no significant differences in the primary combined arrhythmic outcome were observed between the two groups (p =.656). At regression analysis, the only clinical predictor associated with the primary combined outcome was S‐ICD placement for primary prevention (odds ratio: 0.42; p =.013); DT performance instead was not associated with a reduction in primary outcome (p =.375). Conclusion: Implanting an S‐ICD without DT does not appear to impact the safety of defibrillation therapy and overall patients' survival. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

67. Hybrid Minimally Invasive Approach for Transvenous Lead Extraction: A Feasible Technique in High-Risk Patients

Author

Bontempi, Luca, Vassanelli, Francesca, Cerini, Manuel, Bisleri, Gianluigi, Repossini, Alberto, Giroletti, Laura, Inama, Lorenza, Salghetti, Francesca, Liberto, Daria, Giacopelli, Daniele, Raweh, Abdallah, Muneretto, Claudio, and Curnis, Antonio

Subjects
Adult, Male, Pacemaker, Artificial, implantable cardioverter defibrillator, Time Factors, thoracoscopy, Prosthesis Design, minimally invasive thoracotomy, Cardiologists, Risk Factors, Physiology (medical), 80 and over, Humans, Cardiac Resynchronization Therapy Devices, Device Removal, Aged, Aged, 80 and over, Patient Care Team, Surgeons, Length of Stay, pacemaker, Defibrillators, Implantable, lead extraction, Prosthesis Failure, Electrophysiologic Techniques, Cardiac, Feasibility Studies, Female, Treatment Outcome, Thoracoscopy, Thoracotomy, Artificial, Electrophysiologic Techniques, Implantable cardioverter defibrillator, Lead extraction, Minimally invasive thoracotomy, Pacemaker, Cardiology and Cardiovascular Medicine, Implantable, Cardiac, Defibrillators
Abstract

Despite the overall safety, transvenous lead extraction (TLE) remains a challenging procedure with inherent risks, where surgery can still be required in elective cases. In this study, we report our experience with a minimally invasive "hybrid" approach, defined as a procedure performed by an electrophysiologist with the support of a cardiac surgeon in the same operative session.We reported 12 cases of planned hybrid lead extraction; minithoracotomy and thoracoscopy were performed on 10 (83%) and 2 (17%) patients, respectively. A total of 25 leads out of 27 (median lead age 19 years) were successfully extracted with laser, mechanical or combined transvenous sheath. In 3 patients, the direct monitoring of vascular and myocardial integrity allowed for prompt treatment of potential vascular injury during the lead extraction maneuvers. Mean in-hospital stay was 4 ± 2 days. There were no major intraoperative complications and no deaths occurred after 30 days' follow-up.The hybrid approach, with minithoracotomy or thoracoscopy, is feasible and it might increase the safety in the most challenging TLE procedures: the minimally invasive surgical intervention allows for continuous monitoring of the critical cardiac structures and prompt treatment of potential complications.

Published
2017

70. Ranolazine therapy in drug-refractory ventricular arrhythmias

Author

Curnis, Antonio, primary, Salghetti, Francesca, additional, Cerini, Manuel, additional, Vizzardi, Enrico, additional, Sciatti, Edoardo, additional, Vassanelli, Francesca, additional, Villa, Clara, additional, Inama, Lorenza, additional, Raweh, Abdallah, additional, Giacopelli, Daniele, additional, and Bontempi, Luca, additional

Published
2017
Full Text
View/download PDF

71. Thoracoscopic Implantation of An Array Electrode in the Pericardium Transverse Sinus to Reduce Defibrillation Threshold

Author

Curnis, Antonio, primary, Muneretto, Claudio, additional, Bisleri, Gianluigi, additional, Cerini, Manuel, additional, Inama, Lorenza, additional, Salghetti, Francesca, additional, De Vito, Raffaella, additional, Giroletti, Laura, additional, Rosati, Fabrizio, additional, Giacopelli, Daniele, additional, Vassanelli, Francesca, additional, and Bontempi, Luca, additional

Published
2017
Full Text
View/download PDF

73. Hybrid Minimally Invasive Approach for Transvenous Lead Extraction: A Feasible Technique in High-Risk Patients

Author

BONTEMPI, LUCA, primary, VASSANELLI, FRANCESCA, additional, CERINI, MANUEL, additional, BISLERI, GIANLUIGI, additional, REPOSSINI, ALBERTO, additional, GIROLETTI, LAURA, additional, INAMA, LORENZA, additional, SALGHETTI, FRANCESCA, additional, LIBERTO, DARIA, additional, GIACOPELLI, DANIELE, additional, RAWEH, ABDALLAH, additional, MUNERETTO, CLAUDIO, additional, and CURNIS, ANTONIO, additional

Published
2017
Full Text
View/download PDF

74. Unexpected challenging case of coronary sinus lead extraction

Author

Bontempi, Luca, primary, Tempio, Donatella, additional, De Vito, Raffaella, additional, Cerini, Manuel, additional, Salghetti, Francesca, additional, Dasseni, Niccolò, additional, Villa, Clara, additional, Raweh, Abdallah, additional, Inama, Lorenza, additional, Vassanelli, Francesca, additional, Luzi, Mario, additional, and Curnis, Antonio, additional

Published
2017
Full Text
View/download PDF

75. The economic impact of battery longevity in implantable cardioverter-defibrillators for cardiac resynchronization therapy: the hospital and healthcare system perspectives

Author

Landolina, Maurizio, primary, Morani, Giovanni, additional, Curnis, Antonio, additional, Vado, Antonello, additional, D'Onofrio, Antonio, additional, Bianchi, Valter, additional, Stabile, Giuseppe, additional, Crosato, Martino, additional, Petracci, Barbara, additional, Ceriotti, Carlo, additional, Bontempi, Luca, additional, Morosato, Martina, additional, Ballari, Gian Paolo, additional, and Gasparini, Maurizio, additional

Published
2016
Full Text
View/download PDF

76. 96-59: Electrical performance and lead handling evaluation of a new active fixation left ventricular lead: results of an italian multicenter experience

Author

Biffi, Mauro, primary, Giannola, Gabriele, additional, Rordorf, Roberto, additional, Luzzi, Giovanni, additional, Pecora, Domenico, additional, Bongiorni, Maria Grazia, additional, Maglia, Giampiero, additional, Bontempi, Luca, additional, Sagone, Antonio, additional, Infusino, Tommaso, additional, Ziacchi, Matteo, additional, and Lunati, Maurizio, additional

Published
2016
Full Text
View/download PDF

77. 216-63: The economic impact of longevity of implantable cardioverter-defibrillator for cardiac resynchronization therapy from a healthcare service perspective

Author

Landolina, Maurizio, primary, Morani, Giovanni, additional, Curnis, Antonio, additional, Vado, Antonello, additional, Ammendola, Ernesto, additional, D'Onofrio, Antonio, additional, Stabile, Giuseppe, additional, Crosato, Martino, additional, Petracci, Barbara, additional, Ceriotti, Carlo, additional, Bontempi, Luca, additional, Morosato, Martina, additional, Ballari, Gian Paolo, additional, and Gasparini, Maurizio, additional

Published
2016
Full Text
View/download PDF

79. The role of antiarrhythmic drugs in atrial fibrillation

Author

Bontempi, Luca, Vassanelli, Francesca, Alessandro, Lipari, Carlo, Pagnoni, Elisa, Locantore, Mohamed, Elmaghawry, Salghetti, Francesca, Cerini, Manuel, and Curnis, Antonio

Subjects
Elderly, Medical therapy, Atrial fibrillation
Published
2013

81. La resincronizzazione ventricolare

Author

Curnis, Antonio, Mascioli, G, Bontempi, Luca, Racheli, M, Borrelli, A, Cerini, M, Narbone, M. P., and DEI CAS, Livio

Published
2006

82. The economic impact of battery longevity in implantable cardioverter-defibrillators for cardiac resynchronization therapy: the hospital and healthcare system perspectives.

Author

Landolina, Maurizio, Morani, Giovanni, Curnis, Antonio, Vado, Antonello, D'Onofrio, Antonio, Bianchi, Valter, Stabile, Giuseppe, Crosato, Martino, Petracci, Barbara, Ceriotti, Carlo, Bontempi, Luca, Morosato, Martina, Ballari, Gian Paolo, and Gasparini, Maurizio

Subjects
HEART failure treatment, IMPLANTABLE cardioverter-defibrillators, CARDIAC pacemakers, ELECTRIC power supplies to apparatus, CARDIAC pacing, COMPARATIVE studies, COST control, COST effectiveness, DATABASES, ELECTRIC countershock, HEART failure, RESEARCH methodology, MEDICAL care costs, MEDICAL cooperation, RESEARCH, TIME, PRODUCT design, EVALUATION research, MEDICAL equipment reliability, MEDICAL device removal, STATISTICAL models, ECONOMICS, DIAGNOSIS, EQUIPMENT & supplies
Abstract

Aims: Patients receiving cardiac resynchronization therapy defibrillators (CRT-Ds) are likely to undergo one or more device replacements, mainly for battery depletion. We assessed the economic impact of battery depletion on the overall cost of CRT-D treatment from the perspectives of the healthcare system and the hospital. We also compared devices of different generations and from different manufacturers in terms of therapy cost.Methods and Results: We analysed data on 1792 CRT-Ds implanted in 1399 patients in 9 Italian centres. We calculated the replacement probability and the total therapy cost over 6 years, stratified by device generation and manufacturer. Public tariffs from diagnosis-related groups were used together with device prices and hospitalization costs. Generators were from 3 manufacturers: Boston Scientific (667, 37%), Medtronic (973, 54%), and St Jude Medical (152, 9%). The replacement probability at 6 years was 83 and 68% for earlier- and recent-generation devices, respectively. The need for replacement increased total therapy costs by more than 50% over the initial implantation cost for hospitals and by more than 30% for healthcare system. The improved longevity of recent-generation CRT-Ds reduced the therapy cost by ∼6% in both perspectives. Among recent-generation CRT-Ds, the replacement probability of devices from different manufacturers ranged from 12 to 70%. Consequently, the maximum difference in therapy cost between manufacturers was 40% for hospitals and 19% for the healthcare system.Conclusions: Differences in CRT-D longevity strongly affect the overall therapy cost. While the use of recent-generation devices has reduced the cost, significant differences exist among currently available systems. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

84. Predicting the difficulty of a lead extraction procedure

Author

Bontempi, Luca, primary, Vassanelli, Francesca, additional, Cerini, Manuel, additional, D’Aloia, Antonio, additional, Vizzardi, Enrico, additional, Gargaro, Alessio, additional, Chiusso, Francesco, additional, Mamedouv, Rashad, additional, Lipari, Alessandro, additional, and Curnis, Antonio, additional

Published
2014
Full Text
View/download PDF

86. Risk factors for atrial fibrillation recurrence

Author

Vizzardi, Enrico, primary, Curnis, Antonio, additional, Latini, Maria G., additional, Salghetti, Francesca, additional, Rocco, Elena, additional, Lupi, Laura, additional, Rovetta, Riccardo, additional, Quinzani, Filippo, additional, Bonadei, Ivano, additional, Bontempi, Luca, additional, D’Aloia, Antonio, additional, and Dei Cas, Livio, additional

Published
2014
Full Text
View/download PDF

87. Critical appraisal of cardiac implantable electronic devices: complications and management

Author

Padeletti,Luigi, Mascioli,Giosuè, Paoletti Perini,Alessandro, Grifoni,Gino, Perrotta,Laura, Marchese,Procolo, Bontempi,Luca, Curnis,Antonio, Padeletti,Luigi, Mascioli,Giosuè, Paoletti Perini,Alessandro, Grifoni,Gino, Perrotta,Laura, Marchese,Procolo, Bontempi,Luca, and Curnis,Antonio

Abstract

Luigi Padeletti1, Giosuè Mascioli2, Alessandro Paoletti Perini1, Gino Grifoni1, Laura Perrotta1, Procolo Marchese3, Luca Bontempi3, Antonio Curnis31Istituto di Clinica Medica e Cardiologia, Università degli Studi di Firenze, Italia; 2Elettrofisiologia, Istituto Humanitas Gavazzeni, Bergamo, Italia; 3Elettrofisiologia, Spedali Civili, Brescia, ItaliaAbstract: Population aging and broader indications for the implant of cardiac implantable electronic devices (CIEDs) are the main reasons for the continuous increase in the use of pacemakers (PMs), implantable cardioverter-defibrillators (ICDs) and devices for cardiac resynchronization therapy (CRT-P, CRT-D). The growing burden of comorbidities in CIED patients, the greater complexity of the devices, and the increased duration of procedures have led to an augmented risk of infections, which is out of proportion to the increase in implantation rate. CIED infections are an ominous condition, which often implies the necessity of hospitalization and carries an augmented risk of in-hospital death. Their clinical presentation may be either at pocket or at endocardial level, but they can also manifest themselves with lone bacteremia. The management of these infections requires the complete removal of the device and subsequent, specific, antibiotic therapy. CIED failures are monitored by competent public authorities, that require physicians to alert them to any failures, and that suggest the opportune strategies for their management. Although the replacement of all potentially affected devices is often suggested, common practice indicates the replacement of only a minority of devices, as close follow-up of the patients involved may be a safer strategy. Implantation of a PM or an ICD may cause problems in the patients' psychosocial adaptation and quality of life, and may contribute to the development of affective disorders. Clinicians are usually unaware of the psychosocial impact of implanted PMs and

Published
2011

91. Active-fixation coronary sinus pacing lead extraction: A hybrid approach

Author

Curnis, Antonio, primary, Bontempi, Luca, additional, Coppola, Giuseppe, additional, Cerini, Manuel, additional, Gennaro, Francesca, additional, Vassanelli, Francesca, additional, Lipari, Alessandro, additional, Ashofair, Najat, additional, Pagnoni, Carlo, additional, Bisleri, Gianluigi, additional, Munaretto, Claudio, additional, and Dei Cas, Livio, additional

Published
2012
Full Text
View/download PDF

95. Prospective assessment of integrating the existing emergency medical system with automated external defibrillators fully operated by volunteers and laypersons for out-of-hospital cardiac arrest: the Brescia Early Defibrillation Study (BEDS)

Author

Cappato, Riccardo, primary, Curnis, Antonio, additional, Marzollo, Paolo, additional, Mascioli, Giosuè, additional, Bordonali, Tania, additional, Beretti, Sonia, additional, Scalfi, Fausto, additional, Bontempi, Luca, additional, Carolei, Adriana, additional, Bardy, Gust, additional, De Ambroggi, Luigi, additional, and Cas, Livio Dei, additional

Published
2005
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results