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236 results on '"Bonini, MARIA CHIARA"'

51. Editing central memory T-lymphocyte specificity for safe and effective adoptive immunotherapy of leukaemia

Author

Genovese P, Provasi E, Magnani Z, Lombardo A, Pello OM, Kuball J, BONDANZA , ATTILIO, Gregory P, BORDIGNON, CLAUDIO, Holmes M, Greenberg P, Naldini L, BONINI , MARIA CHIARA, Provasi, E, Genovese, P, Magnani, Z, Lombardo, A, Pello, Om, Kuball, J, Bondanza, Attilio, Gregory, Pd, Bordignon, Claudio, Holmes, Mc, Greenberg, Pd, Naldini, L, Bonini, MARIA CHIARA, Gregory, P, Holmes, M, and Greenberg, P

Published
2010

52. Loss of mismatched HLA as a mechanism of leukemia immune escape in family haploidentical and unrelated HSCT: updated analysis of 113 transplants from alternative donors

Author

Vago L, Stanghellini MTL, Clerici D, Crotta A, Messina C, Forno B, Mazzi B, Zanussi M, Turchiano G, Marcatti M, Corti C, Bernardi M, Peccatori J, Rossini S, Fleischhauer K, FERRARI, MAURIZIO, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, CICERI , FABIO, Vago, L, Stanghellini, Mtl, Clerici, D, Crotta, A, Messina, C, Forno, B, Mazzi, B, Zanussi, M, Turchiano, G, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Rossini, S, Ferrari, Maurizio, Bordignon, Claudio, Bonini, MARIA CHIARA, Fleischhauer, K, and Ciceri, Fabio

Published
2010

53. Transplantation Outcome By Disease Risk and Donor Type over Time: An Analysis of 100,000 Allogeneic Stem Cell Transplantation on Behalf of the Acute Leukemia Working Party of the EBMT

Author

Nicolaus Kröger, Myriam Labopin, Carlo Dufour, Rafael F. Duarte, Roni Shouval, Arnon Nagler, Arjan C. Lankester, Peter Bader, Bonini Maria Chiara, John A. Snowden, Silvia Montoto, Joshua A Fein, Jürgen Kuball, Mohamad Mohty, Grzegorz W. Basak, and Jan Styczyński

Subjects
Oncology, medicine.medical_specialty, Acute leukemia, Bone marrow transplantation, business.industry, medicine.medical_treatment, Immunology, Cell Biology, Hematology, Human leukocyte antigen, Hematopoietic stem cell transplantation, Biochemistry, Transplantation, Internal medicine, medicine, Disease risk, Allogeneic hematopoietic stem cell transplant, Stem cell, business
Abstract

Background: Donor type is a key modifiable determinant of outcome following allogeneic hematopoietic stem cell transplantation (HSCT). Utilizing a dataset of more than 100,000 allogeneic transplantations registered with the European Society for Blood and Marrow Transplantation (EBMT), we sought to characterize the evolution of outcomes in transplantation with different donor types across levels of disease-associated risk. Methods: This retrospective study included adult patients treated for hematologic malignancies who underwent first allogeneic HSCT between 2000 and 2015 in EBMT centers. Cord-blood transplantations were excluded, as were patients for whom diagnosis, disease status, or donor relationship were unknown. Missing values were accounted for by multiple imputations. A three-level disease-risk scheme (low, intermediate, and high), was defined by introducing combinations of diagnosis and disease status into a Cox multivariate model for overall survival (OS), similar to the method employed in creating the Disease Risk Index (Armand et al., Blood, 2014). Additional covariates included in the model were reflective of patient, disease, transplant, and center related features. Patients were classified according to a combination of disease risk, donor type, and HSCT year (2000-2005, 2006-2010, 2011-2015). A variable capturing the grouping was introduced into a Cox multivariate analysis adjusted for major transplantation parameters, with the reference category being a matched sibling donor in low-risk disease transplanted between 2011 and 2015. OS was estimated using the Kaplan-Meier method. Competing risk analysis was used to calculate cumulative incidence of non-relapse mortality (NRM) and relapse. Results: A total of 106,086 patients were included in the analysis, with a median age of 48 years (IQR 36-58); Twenty five percent of patients were transplanted between 2000 - 2005, 33% between 2006 and 2010 and 42% between 2011 and 2015. The leading indications for HSCT were acute leukemia (58%), myeloproliferative neoplasms (11%) and non-Hodgkin's lymphomas (10%). Recipients had either HLA matched sibling donors (MSD) (46%), unrelated donors (overall 50%; HLA matched 10/10 (MUD) [20%], mismatched HLA 9/10 (MMUD) [6%], mismatched HLA The risk of overall mortality varied depending on the combination of donor type, disease risk and transplantation year (figure A). In low and intermediate risk disease, a matched sibling donor had the most favorable outcome across year-periods. However, in high-risk disease, overlapping hazard ratios (HRs) were observed between MSD and MUD in 2011-2015 (2.8 [2.6-3.0] versus 3.0 [2.8-3.2], respectively). The cumulative incidence for NRM for MSD vs. MUD in high-risk disease transplanted from 2011-2015 was 26.1% (23.8-28.6) vs. 35.3% (32.6-38.3, p < 0.0001), respectively. Similarly, relapse incidence was 50.7% (48.0-53.6) vs. 41.0% (38.3-44.0, p < 0.0001). In high disease risk, the risk for mortality has decreased over the years for MSD and MUD, and even more so for transplantations from Haplo donors (2000-2005 HR 5.11 [4.3-6.1]; 2011-2015 HR 3.9 [3.5-4.3]). In the low-risk setting, transplantations from Haplo donors had a comparable risk to MSD and MUD (2011-2015 Low risk: MSD reference, MUD 1.2 [1.1-1.3], Haplo 1.3 [1.2-1.5]). A representative example is seen in Figure B: the probability of 2-year overall survival between 2011-2015, low risk in MSD was 66.5% (95% CI 65.0-68.0), MUD 63.4% (61.7-65.1), and Haplo 60.4 (56.9-64.1). Conclusion: Survival has improved following allogeneic HSCT over the past two decades. This improvement is especially clear in the case of haploidentical donors, though MSD and MUD are still associated with better outcomes. In high-risk disease, the risk of mortality is equivalent between matched sibling and matched unrelated donors. Notably, the probability for NRM is higher with MUD, but relapse incidence is lower, emphasizing the importance of graft-versus-tumor effect in the high-risk setting and the ongoing need for NRM reduction strategies. Disclosures Kröger: Janssen Global Services, LLC: Speakers Bureau; Amgen Inc.: Speakers Bureau; Novartis AG: Research Funding; RIEMSER Pharma: Research Funding; Neovii Pharmaceuticals AG: Speakers Bureau; Novartis AG: Speakers Bureau; Sanofi: Speakers Bureau. Bader: Novartis, Medac, Amgen, Riemser, Neovii: Consultancy, Honoraria, Research Funding. Kuball: Miltenyi: Research Funding; Gadeta (www.gadeta.nl): Consultancy, Equity Ownership, Patents & Royalties: on gdT cells and receptors and isolation strategies , Research Funding. Snowden: Sanofi: Honoraria. Mohty: Sanofi: Honoraria, Speakers Bureau.

Published
2017
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54. Cell-Specific Transcriptional Regulatory Domains Attract Gamma Retroviral Integration in the Human Genome

Author

Cattoglio C, Felice B, Cittaro D, Pellin D, AMBROSI , ALESSANDRO, Rizzi E, De Bellis G, BONINI , MARIA CHIARA, Maruggi G, Miselli F, Schmidt M, Luzi L, Recchia A, Mavilio F., Proceedings of the ASGT, Cattoglio, C, Felice, B, Cittaro, D, Pellin, D, Ambrosi, Alessandro, Rizzi, E, De Bellis, G, Bonini, MARIA CHIARA, Maruggi, G, Miselli, F, Schmidt, M, Luzi, L, Recchia, A, and Mavilio, F.

Published
2009

55. Leukemic Dendritic Cells Expand Central Memory T Lymphocytes From HCT Donors Able to React against the Original Leukemia in Vitro and In Vivo

Author

Casucci M, Perna SK, BONDANZA , ATTILIO, Magnani Z, Bernardi M, Crotta A, Tresoldi C, Fleischhauer K, Provasi E, PONZONI , MAURILIO, Caligaris Cappio F, CICERI, FABIO, BORDIGNON, CLAUDIO, Cignetti A, BONINI , MARIA CHIARA, Casucci, M, Perna, Sk, Bondanza, Attilio, Magnani, Z, Bernardi, M, Crotta, A, Tresoldi, C, Fleischhauer, K, Provasi, E, Ponzoni, Maurilio, Caligaris Cappio, F, Ciceri, Fabio, Bordignon, Claudio, Cignetti, A, and Bonini, MARIA CHIARA

Published
2009

56. GENOMIC LOSS OF MISMATCHED HLA IN LEUKEMIA IS A MAJOR MECHANISM OF IN VIVO ESCAPE FROM T CELL IMMUNOSURVEILLANCE FOLLOWING HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION

Author

Vago L, Zanussi M, Mazzi B, Barlassina C, Stanghellini MTL, Peccatori J, BORDIGNON, CLAUDIO, CICERI, FABIO, Fleischhauer K., BONINI , MARIA CHIARA, Vago, L, Zanussi, M, Mazzi, B, Barlassina, C, Stanghellini, Mtl, Peccatori, J, Bordignon, Claudio, Ciceri, Fabio, Bonini, MARIA CHIARA, and Fleischhauer, K.

Published
2009

57. Loss of Mismatched HLA as a Mechanism of Leukemia Immune Escape in Family Haploidentical and Unrelated HSCT: Analysis of 103 Transplants From Alternative Donors

Author

Vago L, Stanghellini MTL, Clerici D, Crotta A, Messina C, Forno B, Mazzi B, Zanussi M, Assanelli A, Marktel S, Marcatti M, Corti C, Bernardi M, Peccatori J, Rossini S, FERRARI, MAURIZIO, BORDIGNON, CLAUDIO, Fleischhauer K, CICERI, FABIO, BONINI , MARIA CHIARA, Vago, L, Stanghellini, Mtl, Clerici, D, Crotta, A, Messina, C, Forno, B, Mazzi, B, Zanussi, M, Assanelli, A, Marktel, S, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Rossini, S, Ferrari, Maurizio, Bordignon, Claudio, Bonini, MARIA CHIARA, Fleischhauer, K, and Ciceri, Fabio

Published
2009

59. Immune Reconstitution and Immune Correlates of Clinical Outcome in Acute Leukemia Patients Treated with Haploidentical stem cell transplantation

Author

Forcina A, Noviello M, Valtolina V, BONDANZA , ATTILIO, Clerici D, Vago L, Mastaglio S, Lupo Stanghellini MT, Fleischhauer K, Corti C, Bernardi M, Peccatori J, BORDIGNON, CLAUDIO, CICERI , FABIO, BONINI , MARIA CHIARA, Forcina, A, Noviello, M, Valtolina, V, Bondanza, Attilio, Clerici, D, Vago, L, Mastaglio, S, Lupo Stanghellini, Mt, Fleischhauer, K, Corti, C, Bernardi, M, Peccatori, J, Bordignon, Claudio, Ciceri, Fabio, and Bonini, MARIA CHIARA

Published
2009

60. Thiotepa-cyclophosphamide high-dose immunosuppressive therapy with autologous haematopoietic stem cell transplantation in aggressive forms of multiple sclerosis: results in 9 patients

Author

Greco R, Moiola L, Roccia T, Radaelli M, Peccatori J, BONINI , MARIA CHIARA, Corti C, Bernardi M, Stanghellini MTL, COMI, GIANCARLO, CICERI , FABIO, Greco, R, Moiola, L, Roccia, T, Radaelli, M, Peccatori, J, Bonini, MARIA CHIARA, Corti, C, Bernardi, M, Stanghellini, Mtl, Comi, Giancarlo, and Ciceri, Fabio

Published
2009

62. Rapamycin-based GvHD prophylaxis after T-cell replete unmanipulated haploidentical peripheral stem cell transplantation for advanced leukaemias: preliminary results of the TrRaMM study

Author

Peccatori J, Clerici D, Forcina A, Messina C, Lupo Stanghellini MT, Noviello M, Valtolina V, Giorgiani G, Crocchiolo R, Marcatti M, Mastaglio S, Assanelli A, Guggiari E, Crotta A, Gattillo S, Rossini S, Corti C, Bernardi M, Locatelli F, CICERI, FABIO, BONINI , MARIA CHIARA, Peccatori, J, Clerici, D, Forcina, A, Messina, C, Lupo Stanghellini, Mt, Noviello, M, Valtolina, V, Giorgiani, G, Crocchiolo, R, Marcatti, M, Mastaglio, S, Assanelli, A, Guggiari, E, Crotta, A, Gattillo, S, Rossini, S, Corti, C, Bernardi, M, Locatelli, F, Bonini, MARIA CHIARA, and Ciceri, Fabio

Published
2009

64. SECOND ALLOGENEIC STEM CELL TRANSPLANTATION AS SALVAGE TREATMENT IN RELAPSED HAEMATOLOGICAL MALIGNANCIES: FEASIBILITY AND OUTCOME IN 26 PATIENTS

Author

Stanghellini MTL, Assanelli AA, Crocchiolo R, Clerici D, Tassara M, Calbi V, Bernardi M, Marcatti M, Corti C, Carrabba MG, Lunghi F, Guggiari E, Camba L, BONINI , MARIA CHIARA, Peccatori J, CICERI , FABIO, Stanghellini, Mtl, Assanelli, Aa, Crocchiolo, R, Clerici, D, Tassara, M, Calbi, V, Bernardi, M, Marcatti, M, Corti, C, Carrabba, Mg, Lunghi, F, Guggiari, E, Camba, L, Bonini, MARIA CHIARA, Peccatori, J, and Ciceri, Fabio

Published
2009

66. Trapianto di cellule staminali ematopoietiche

Author

Lupo Stanghellini MT, Peccatori J, Assanelli A, CICERI, FABIO, BONINI , MARIA CHIARA, Rugarli C, Lupo Stanghellini, Mt, Peccatori, J, Assanelli, A, Ciceri, Fabio, and Bonini, MARIA CHIARA

Published
2009

67. Suicide gene therapy of GvHD fully preserves immunocompetence after haploidentical hemopoietic cell transplantation

Author

Noviello M, Forcina A, Valtolina V, BONDANZA , ATTILIO, Clerici D, Vago L, Mastaglio S, Lupo Stanghellini MT, Fleischhauer K, Corti C, Bernardi M, Peccatori J, BORDIGNON, CLAUDIO, CICERI , FABIO, BONINI , MARIA CHIARA, Noviello, M, Forcina, A, Valtolina, V, Bondanza, Attilio, Clerici, D, Vago, L, Mastaglio, S, Lupo Stanghellini, Mt, Fleischhauer, K, Corti, C, Bernardi, M, Peccatori, J, Bordignon, Claudio, Ciceri, Fabio, and Bonini, MARIA CHIARA

Published
2009

68. Targeted disruption of t cell receptor genes using engineered zinc finger protein nucleases

Author

BONINI , MARIA CHIARA, C, Pietro Genovese, Philip D. Gregory, Michael C. Holmes, Luigi Naldini, David Paschon, Elena Provasi, Lei Zhang, Bonini, MARIA CHIARA, Pietro, Genovese, Gregory, Philip D., Holmes, Michael C., Naldini, Luigi, David, Paschon, Elena, Provasi, and Lei, Zhang

Abstract

Disclosed herein are methods and compositions for inactivating TCR genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain in conditions able to preserve cell viability. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided. Disclosed herein are also methods and compositions for expressing a functional exogenous TCR in the absence of endogenous TCR expression in T lymphocytes, including lymphocytes with a central memory phenotype. Polynucleotides encoding exogenous TCR, vectors comprising polynucleotides encoding exogenous TCR and cells comprising polynucleotides encoding exogenous TCR and/or cells comprising exogenous TCR are also provided.

Published
2009

69. Immunostimulatory leukemic dendritic cells can efficiently expand leukemia-reactive T cells from HSCT donors

Author

Casucci M, Perna SK, BONDANZA , ATTILIO, Magnani Z, Bernardi M, Crotta A, Tresoldi C, Fleischhauer K, Caligaris Cappio F, CICERI, FABIO, BORDIGNON, CLAUDIO, Cignetti A, BONINI , MARIA CHIARA, Casucci, M, Perna, Sk, Bondanza, Attilio, Magnani, Z, Bernardi, M, Crotta, A, Tresoldi, C, Fleischhauer, K, Caligaris Cappio, F, Ciceri, Fabio, Bordignon, Claudio, Cignetti, A, and Bonini, MARIA CHIARA

Published
2009

72. T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia

Author

Provasi E, Genovese P, Magnani Z, Pello OM, Kuball J, Lombardo A, BONDANZA , ATTILIO, Gregory PD, BORDIGNON, CLAUDIO, Holmes MC, Greenberg PD, Naldini L, BONINI , MARIA CHIARA, Provasi, E, Genovese, P, Magnani, Z, Pello, Om, Kuball, J, Lombardo, A, Bondanza, Attilio, Gregory, Pd, Bordignon, Claudio, Holmes, Mc, Greenberg, Pd, Naldini, L, and Bonini, MARIA CHIARA

Published
2009

73. REQUIREMENTS FOR RETROVIRAL TARGETING OF A SUICIDE GENE TO ALLOREACTIVE SELF-RENEWING MEMORY LYMPHOCYTES FOR ADOPTIVE IMMUNOTHERAPY OF LEUKEMIA

Author

BONDANZA , ATTILIO, Kaneko S, Hambach L, Mastaglio S, Nijmeijer B, Van Halteren A, PONZONI , MAURILIO, Aldrighetti L, Toma S, Radrizzani M, CICERI , FABIO, BORDIGNON, CLAUDIO, Goulmy E, BONINI , MARIA CHIARA, Bondanza, Attilio, Kaneko, S, Hambach, L, Mastaglio, S, Nijmeijer, B, Van Halteren, A, Ponzoni, Maurilio, Aldrighetti, L, Toma, S, Radrizzani, M, Ciceri, Fabio, Bordignon, Claudio, Goulmy, E, and Bonini, MARIA CHIARA

Published
2008

74. Efficient differentiation of primary and secondary acute myeloid leukaemias into functionally competent leukaemic dendritic cells to improve graft-versus-leukemia effect

Author

Casucci M, Perna S, Magnani Z, Bernardi M, Crotta A, Cignetti A, Caligaris Cappio F, CICERI, FABIO, BORDIGNON, CLAUDIO, BONDANZA , ATTILIO, BONINI , MARIA CHIARA, Casucci, M, Perna, S, Bondanza, Attilio, Magnani, Z, Bernardi, M, Crotta, A, Cignetti, A, Caligaris Cappio, F, Ciceri, Fabio, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2008

75. Efficient differentiation of primary and secondary acute myeloid leukemias into functionally competent leukemic dendritic cells to improve the graft versus leukemia effect

Author

Casucci M, Perna SK, BONDANZA , ATTILIO, Magnani Z, Bernardi M, Crotta A, Cignetti A, Tresoldi C, Fleischhauer K, Caligaris Cappio F, CICERI, FABIO, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, Casucci, M, Perna, Sk, Bondanza, Attilio, Magnani, Z, Bernardi, M, Crotta, A, Cignetti, A, Tresoldi, C, Fleischhauer, K, Caligaris Cappio, F, Ciceri, Fabio, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2008

77. TK007 phase II study final analysis. Genetically modified donor lymphocytes abate transplant related mortality and increase leukaemia-free survival providing early immune reconstitution after haploidentical haematopoietic stem cell transplantation

Author

Stanghellini MTL, CICERI, FABIO, BONINI , MARIA CHIARA, BONDANZA , ATTILIO, Traversari C, Toma S, Salomoni M, Turchetto L, Colombi S, Bernardi M, Peccatori J, Pescarollo A, Servida P, Magnani Z, Perna SK, Valtolina V, Crippa F, Callegaro L, Spoldi E, Fleischhauer K, PONZONI , MAURILIO, Vago L, Santoro A, Todisco E, Apperley J, Slavin S, Weissinger E, Hertenstein B, Bregni M, Stampino CG, Bruzzi P, BORDIGNON, CLAUDIO, Stanghellini, Mtl, Ciceri, Fabio, Bonini, MARIA CHIARA, Bondanza, Attilio, Traversari, C, Toma, S, Salomoni, M, Turchetto, L, Colombi, S, Bernardi, M, Peccatori, J, Pescarollo, A, Servida, P, Magnani, Z, Perna, Sk, Valtolina, V, Crippa, F, Callegaro, L, Spoldi, E, Fleischhauer, K, Ponzoni, Maurilio, Vago, L, Santoro, A, Todisco, E, Apperley, J, Slavin, S, Weissinger, E, Hertenstein, B, Bregni, M, Stampino, Cg, Bruzzi, P, and Bordignon, Claudio

Published
2008

78. Direct antigen presentation by leukemic dendritic cells promotes expansion of allogeneic leukemia-reactive T lymphocytes

Author

Casucci M, Perna SK, BONDANZA , ATTILIO, Magnani Z, Bernardi M, Crotta A, Cignetti A, Tresoldi C, Fleischhauer K, Caligaris Cappio F, CICERI, FABIO, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, Casucci, M, Perna, Sk, Bondanza, Attilio, Magnani, Z, Bernardi, M, Crotta, A, Cignetti, A, Tresoldi, C, Fleischhauer, K, Caligaris Cappio, F, Ciceri, Fabio, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2008

81. SUICIDE GENE TRANSFER INTO DONOR LYMPHOCYTES ALLOWS EARLY AND EFFECTIVE IMMUNE-RECONSTITUTION AFTER FAMILY HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LEUKEMIAS: RESULTS OF THE TK007 STUDY

Author

BONINI, MARIA CHIARA, CICERI, FABIO, BONDANZA, ATTILIO, PONZONI, MAURILIO, BORDIGNON, CLAUDIO, Lupo, Smt, Traversari, C, Salomoni, M, Turchetto, L, Colombi, S, Bernardi, M, Peccatori, J, Magnani, Z, Perna, Sk, Valtolina, V, Crippa, F, Callegaro, L, Spoldi, E, Crocchiolo, R, Fleischhauer, K, Vago, L, Santoro, A, Todisco, E, Apperley, J, Slavin, S, Weissinger, Em, Hertenstein, B, Bregni, M, Gallo, Sc, Bruzzi, P, Bonini, MARIA CHIARA, Ciceri, Fabio, Lupo, Smt, Bondanza, Attilio, Traversari, C, Salomoni, M, Turchetto, L, Colombi, S, Bernardi, M, Peccatori, J, Magnani, Z, Perna, Sk, Valtolina, V, Crippa, F, Callegaro, L, Spoldi, E, Crocchiolo, R, Fleischhauer, K, Ponzoni, Maurilio, Vago, L, Santoro, A, Todisco, E, Apperley, J, Slavin, S, Weissinger, Em, Hertenstein, B, Bregni, M, Gallo, Sc, Bruzzi, P, and Bordignon, Claudio

Published
2008

82. Genomic Loss of the Mismatched HLA Locus in Leukemia Is a Major Mechanism of in Vivo Escape from T Cell Immunosurveillance Following Haploidentical HSCT

Author

Vago L, Perna SK, Zanussi M, Mazzi B, Stanghellini MTL, Perrelli NF, Forno B, Corti C, Bernardi M, Peccatori J, FERRARI, MAURIZIO, Rossini S, Roncarolo MG, BORDIGNON, CLAUDIO, CICERI, FABIO, Fleischhauer K., BONINI , MARIA CHIARA, Vago, L, Perna, Sk, Zanussi, M, Mazzi, B, Stanghellini, Mtl, Perrelli, Nf, Forno, B, Corti, C, Bernardi, M, Peccatori, J, Ferrari, Maurizio, Rossini, S, Roncarolo, Mg, Bordignon, Claudio, Bonini, MARIA CHIARA, Ciceri, Fabio, and Fleischhauer, K.

Published
2008

83. Targeting of a therapeutic suicide gene to human alloreactive memory T-cells with stem-cell features requires IL-7 and IL-15

Author

BONDANZA, ATTILIO, PONZONI, MAURILIO, CICERI, FABIO, BORDIGNON, CLAUDIO, BONINI, MARIA CHIARA, Hambach, L, Kaneko, S, Mastaglio, S, Nijmeijer, B, van Halteren, A, Aldrighetti, L, Toma, S, Radrizzani, M, Goulmy, E, Bondanza, Attilio, Hambach, L, Kaneko, S, Mastaglio, S, Nijmeijer, B, van Halteren, A, Ponzoni, Maurilio, Aldrighetti, L, Toma, S, Radrizzani, M, Ciceri, Fabio, Bordignon, Claudio, Goulmy, E, and Bonini, MARIA CHIARA

Published
2008

84. The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity

Author

Vago L, Zino E, Di Terlizzi S, Forno B, Lupo Stanghellini MT, Mazzi B, Palini A, Rossini S, Roncarolo MG, BONINI , MARIA CHIARA, CICERI , FABIO, BORDIGNON, CLAUDIO, Fleischhauer K., Vago, L, Zino, E, Di Terlizzi, S, Forno, B, Lupo Stanghellini, Mt, Mazzi, B, Palini, A, Rossini, S, Roncarolo, Mg, Bonini, MARIA CHIARA, Ciceri, Fabio, Bordignon, Claudio, and Fleischhauer, K.

Published
2007

85. Suicide gene therapy with central memory human T lymphocytes for a graft-versus-leukemia effect and control of graft-versus-host disease

Author

BONDANZA , ATTILIO, Kaneko S, Hambach L, Mastaglio S, PONZONI , MAURILIO, Aldrighetti L, Toma S, Radrizzani M, Catamancio SLS, CICERI , FABIO, BORDIGNON, CLAUDIO, Goulmy E, BONINI , MARIA CHIARA, Bondanza, Attilio, Kaneko, S, Hambach, L, Mastaglio, S, Ponzoni, Maurilio, Aldrighetti, L, Toma, S, Radrizzani, M, Catamancio, Sl, Ciceri, Fabio, Bordignon, Claudio, Goulmy, E, and Bonini, MARIA CHIARA

Published
2007

87. Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT

Author

Vago L, Fomot B, Zino E, Di Terlizzi S, Stanghellini MTL, Crocchiolo R, Pema SK, BONDANZA , ATTILIO, Mazzi B, Peccatori J, Roncarolo MG, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, CICERI , FABIO, Fleischhauer K., Vago, L, Fomot, B, Zino, E, Di Terlizzi, S, Stanghellini, Mtl, Crocchiolo, R, Pema, Sk, Bondanza, Attilio, Mazzi, B, Peccatori, J, Roncarolo, Mg, Bordignon, Claudio, Bonini, MARIA CHIARA, Ciceri, Fabio, and Fleischhauer, K.

Published
2007

88. High alloreactive potential of suicide gene expressing central memory T lymphocytes cultured with homeostatic Gamma-chain cytokines for the cure of hematological malignancies

Author

Kaneko S, Mastaglio S, BONDANZA , ATTILIO, PONZONI , MAURILIO, Aldrighetti L, Toma S, Radrizzani M, La Seta Catamancio S, CICERI , FABIO, Nagasawa T, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, Kaneko, S, Mastaglio, S, Bondanza, Attilio, Ponzoni, Maurilio, Aldrighetti, L, Toma, S, Radrizzani, M, La Seta Catamancio, S, Ciceri, Fabio, Nagasawa, T, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2007

89. Infusions of HSV-TK engineered donor lymphocytes promote the expansion of host-restricted viral-specific T lymphocytes and protect patients undergoing haploidentical stem cell transplantation from infectious mortality

Author

Provasi E, Stanghellini MTL, Magnani Z, Perna SK, Forcina A, Bernardi M, Peccatori J, Crippa F, Valtolina V, Salomoni M, Turchetto L, Toma S, Traversari C, Colombi S, Stampino CG, MANFREDI, ANGELO ANDREA M. A., BORDIGNON, CLAUDIO, CICERI , FABIO, BONDANZA , ATTILIO, ROVERE QUERINI , PATRIZIA, BONINI , MARIA CHIARA, Provasi, E, Ciceri, Fabio, Stanghellini, Mtl, Bondanza, Attilio, Magnani, Z, Perna, Sk, Forcina, A, Bernardi, M, Peccatori, J, Crippa, F, Valtolina, V, Salomoni, M, Turchetto, L, Toma, S, Traversari, C, Colombi, S, Stampino, Cg, ROVERE QUERINI, Patrizia, Manfredi, ANGELO ANDREA M. A., Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2007

90. Impaired GvL potential of natural killer cells early reconstituting following haploidentical HSCT

Author

Vago L, Zino E, Di Terlizzi S, Forno B, Stanghellini MTL, Pema SK, Mazzi B, Peccatori J, Rossini S, Roncarolo MG, Fleischhauer K., BONINI , MARIA CHIARA, CICERI , FABIO, BORDIGNON, CLAUDIO, Vago, L, Zino, E, Di Terlizzi, S, Forno, B, Stanghellini, Mtl, Pema, Sk, Mazzi, B, Peccatori, J, Rossini, S, Roncarolo, Mg, Bonini, MARIA CHIARA, Ciceri, Fabio, Bordignon, Claudio, and Fleischhauer, K.

Published
2006

91. Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT

Author

BONINI , MARIA CHIARA, CICERI , FABIO, Lupo Stanghellini MT, BONDANZA , ATTILIO, Magnani Z, Perna SK, Bernardi M, Peccatori J, Pescarollo A, Servida P, Crippa F, Callegaro L, Vago L, Fleischhauer K, Salomoni M, Turchetto L, Toma S, Traversari C, Bruzzi P, Castagna L, Santoro A, Apperley J, Slavin S, Colombi S, Gallo Stampino C, Bregni M, BORDIGNON, CLAUDIO, Bonini, MARIA CHIARA, Ciceri, Fabio, Lupo Stanghellini, Mt, Bondanza, Attilio, Magnani, Z, Perna, Sk, Bernardi, M, Peccatori, J, Pescarollo, A, Servida, P, Crippa, F, Callegaro, L, Vago, L, Fleischhauer, K, Salomoni, M, Turchetto, L, Toma, S, Traversari, C, Bruzzi, P, Castagna, L, Santoro, A, Apperley, J, Slavin, S, Colombi, S, Gallo Stampino, C, Bregni, M, and Bordignon, Claudio

Published
2006

92. High alloreactive potential of central memory T-lymphocytes expressing a suicide gene for the cure of hematologic malignancies

Author

Kaneko S, Mastaglio S, BONDANZA , ATTILIO, PONZONI , MAURILIO, Aldrighetti L, Toma S, Radrizzani M, Catamancio SLS, CICERI , FABIO, Nagasawa T, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, Kaneko, S, Mastaglio, S, Bondanza, Attilio, Ponzoni, Maurilio, Aldrighetti, L, Toma, S, Radrizzani, M, Catamancio, Sl, Ciceri, Fabio, Nagasawa, T, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2006

93. Haematopoietic chimerism after T-cell depleted stem cell transplantation: early detection of host chimerism by patient-specific HLA alleles analysis is a sensitive marker for relapse of high-risk haematologic malignancies

Author

Clerici TD, Mazzi B, Peccatori J, Bernardi M, Stanghellini MTL, BONINI , MARIA CHIARA, Fleischhauer K, BORDIGNON, CLAUDIO, CICERI , FABIO, Clerici, Td, Mazzi, B, Peccatori, J, Bernardi, M, Stanghellini, Mtl, Bonini, MARIA CHIARA, Fleischhauer, K, Bordignon, Claudio, and Ciceri, Fabio

Published
2006

94. Foscarnet is an effective pre-emptive treatment of cytomegalovirus reactivation after T-cell depleted haploidentical stem cell transplantation

Author

Lupo Stanghellini MT, Lunghi F, Corti C, Guggiari E, Crocchiolo R, Roccia TR, Brurnoventre M, Servida P, Bernardi M, Peccatori J, Crippa F, BONINI , MARIA CHIARA, BORDIGNON, CLAUDIO, CICERI , FABIO, Lupo Stanghellini, Mt, Lunghi, F, Bonini, MARIA CHIARA, Corti, C, Guggiari, E, Crocchiolo, R, Roccia, Tr, Brurnoventre, M, Servida, P, Bernardi, M, Peccatori, J, Crippa, F, Bordignon, Claudio, and Ciceri, Fabio

Published
2006

96. Infusions of HSV-TK genetically modified donor lymphocytes enable a wider use of partially mismatched allogeneic transplantation by reducing infection related mortality and improving survival in high risk acute leukemia

Author

CICERI , FABIO, BONINI , MARIA CHIARA, Stanghellini ML, Santoro A, Slavin S, Apperley J, Bruzzi P, Toma S, Stampino CG, Bregni M, BORDIGNON, CLAUDIO, San Raffaele H., Ciceri, Fabio, Bonini, MARIA CHIARA, Stanghellini, Ml, Santoro, A, Slavin, S, Apperley, J, Bruzzi, P, Toma, S, Stampino, Cg, Bregni, M, Bordignon, Claudio, and San Raffaele, H.

Published
2006

97. Secondary SOLID Tumors after Allogeneic STEM CELL Transplantation: A CROSS-Sectional Evaluation in 260 Adults at 1-Year Follow-up

Author

Lupo-Stanghellini, Maria Teresa, primary, Assanelli, Andrea, additional, Greco, Raffaella, additional, Giglio, Fabio, additional, Mastaglio, Sara, additional, Morelli, Mara, additional, Pavesi, Francesca, additional, Sala, Elisa, additional, Brambilla, Margherita, additional, Piemontese, Simon, additional, Vago, Luca, additional, Messina, Carlo, additional, Dalto, Serena Camilla, additional, Lorentino, Francesca, additional, Mannina, Daniele, additional, Malerba, Ambra, additional, Marcatti, Magda, additional, Guggiari, Elena, additional, Marktel, Sarah, additional, Carrabba, Matteo Giovanni, additional, Lunghi, Francesca, additional, Bernardi, Massimo, additional, Bonini, Maria Chiara, additional, Corti, Consuelo, additional, Peccatori, Jacopo, additional, and Ciceri, Fabio, additional

Published
2016
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99. Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

Author

BONDANZA , ATTILIO, PONZONI , MAURILIO, CICERI , FABIO, BONINI , MARIA CHIARA, Valtolina V, Magnani Z, Kaneko S, Sanvito F, Bonyhadi M, Traversari C, Toma S, Radrizzani M, La Seta Catamancio S, Fleischhauer K, BORDIGNON, CLAUDIO, Bondanza, Attilio, Valtolina, V, Magnani, Z, Kaneko, S, Ponzoni, Maurilio, Sanvito, F, Bonyhadi, M, Traversari, C, Toma, S, Radrizzani, M, La Seta Catamancio, S, Fleischhauer, K, Ciceri, Fabio, Bordignon, Claudio, and Bonini, MARIA CHIARA

Published
2005

100. Engraftment of CD34+ haplo-identical allogeneic cells after a non-TBI conditioning and ATG Fresenius: a single-centre experience in 30 patients

Author

CICERI , FABIO, BONINI , MARIA CHIARA, BORDIGNON, CLAUDIO, Peccatori J, Stanghellini ML, Bernardi M, Zappone E, Di Matteo P, Perna S, Corti C, Lunghi F, Callegaro L, Fleischhauer K, Servida P, Pescarollo A, Bregni M., Ciceri, Fabio, Peccatori, J, Stanghellini, Ml, Bonini, MARIA CHIARA, Bernardi, M, Zappone, E, Di Matteo, P, Perna, S, Corti, C, Lunghi, F, Callegaro, L, Fleischhauer, K, Servida, P, Pescarollo, A, Bordignon, Claudio, and Bregni, M.

Published
2005

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