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5,915 results on '"Boffetta, Paolo"'

51. Dietary glycaemic index, glycaemic load and head and neck cancer risk: a pooled analysis in an international consortium

Author

Chang, Chun-Pin, La Vecchia, Carlo, Serraino, Diego, Olshan, Andrew F, Zevallos, Jose P, Morgenstern, Hal, Levi, Fabio, Garavello, Werner, Kelsey, Karl, McClean, Michael, Chen, Chu, Schwartz, Stephen M, Schantz, Stimson, Yu, Guo-Pei, Boffetta, Paolo, Hashibe, Mia, Lee, Yuan-Chin Amy, Parpinel, Maria, Augustin, Livia SA, Turati, Federica, Zhang, Zuo-Feng, and Edefonti, Valeria

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Digestive Diseases, Prevention, Dental/Oral and Craniofacial Disease, Cancer, Case-Control Studies, Female, Glycemic Index, Glycemic Load, Head and Neck Neoplasms, Humans, Male, Surveys and Questionnaires, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

High dietary glycaemic index (GI) and glycaemic load (GL) may increase cancer risk. However, limited information was available on GI and/or GL and head and neck cancer (HNC) risk. We conducted a pooled analysis on 8 case-control studies (4081 HNC cases; 7407 controls) from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. We estimated the odds ratios (ORs) and 95% confidence intervals (CIs) of HNC, and its subsites, from fixed- or mixed-effects logistic models including centre-specific quartiles of GI or GL. GI, but not GL, had a weak positive association with HNC (ORQ4 vs. Q1 = 1.16; 95% CI = 1.02-1.31). In subsites, we found a positive association between GI and laryngeal cancer (ORQ4 vs. Q1 = 1.60; 95% CI = 1.30-1.96) and an inverse association between GL and oropharyngeal cancer (ORQ4 vs. Q1 = 0.78; 95% CI = 0.63-0.97). This pooled analysis indicates a modest positive association between GI and HNC, mainly driven by laryngeal cancer.

Published
2020

52. Age at start of using tobacco on the risk of head and neck cancer: Pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE)

Author

Chang, Chun-Pin, Chang, Shen-Chih, Chuang, Shu-Chun, Berthiller, Julien, Ferro, Gilles, Matsuo, Keitaro, Wünsch-Filho, Victor, Toporcov, Tatiana N, de Carvalho, Marcos Brasilino, La Vecchia, Carlo, Olshan, Andrew F, Zevallos, Jose P, Serraino, Diego, Muscat, Joshua, Sturgis, Erich M, Li, Guojun, Morgenstern, Hal, Levi, Fabio, Dal Maso, Luigino, Smith, Elaine, Kelsey, Karl, McClean, Michael, Vaughan, Thomas L, Lazarus, Philip, Ramroth, Heribert, Chen, Chu, Schwartz, Stephen M, Winn, Deborah M, Bosetti, Cristina, Edefonti, Valeria, Garavello, Werner, Negri, Eva, Hayes, Richard B, Purdue, Mark P, Boccia, Stefania, Cadoni, Gabriella, Shangina, Oxana, Koifman, Rosalina, Curado, Maria Paula, Vilensky, Marta, Swiatkowska, Beata, Herrero, Rolando, Franceschi, Silvia, Benhamou, Simone, Fernandez, Leticia, Menezes, Ana MB, Daudt, Alexander W, Mates, Dana, Schantz, Stimson, Yu, Guo-Pei, Lissowska, Jolanta, Brenner, Hermann, Fabianova, Eleonora, Rudnai, Peter, Brennan, Paul, Boffetta, Paolo, Zhang, Zuo-Feng, Hashibe, Mia, and Lee, Yuan-Chin Amy

Subjects
Biomedical and Clinical Sciences, Epidemiology, Health Services and Systems, Health Sciences, Public Health, Oncology and Carcinogenesis, Prevention, Rare Diseases, Cancer, Tobacco Smoke and Health, Dental/Oral and Craniofacial Disease, Substance Misuse, Tobacco, Aetiology, 2.2 Factors relating to the physical environment, Good Health and Well Being, Adult, Age Factors, Aged, Case-Control Studies, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Risk Factors, Nicotiana, Age at start of tobacco use, Head and neck cancer, Oral cancer, Oropharyngeal cancer, Hypopharyngeal cancer, Laryngeal cancer, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

BackgroundTobacco use is a well-established risk factor for head and neck cancer (HNC). However, less is known about the potential impact of exposure to tobacco at an early age on HNC risk.MethodsWe analyzed individual-level data on ever tobacco smokers from 27 case-control studies (17,146 HNC cases and 17,449 controls) in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using random-effects logistic regression models.ResultsWithout adjusting for tobacco packyears, we observed that younger age at starting tobacco use was associated with an increased HNC risk for ever smokers (OR

Published
2019

56. Correction: Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes

Author

Berndt, Sonja I., Vijai, Joseph, Benavente, Yolanda, Camp, Nicola J., Nieters, Alexandra, Wang, Zhaoming, Smedby, Karin E., Kleinstern, Geffen, Hjalgrim, Henrik, Besson, Caroline, Skibola, Christine F., Morton, Lindsay M., Brooks-Wilson, Angela R., Teras, Lauren R., Breeze, Charles, Arias, Joshua, Adami, Hans-Olov, Albanes, Demetrius, Anderson, Kenneth C., Ansell, Stephen M., Bassig, Bryan, Becker, Nikolaus, Bhatti, Parveen, Birmann, Brenda M., Boffetta, Paolo, Bracci, Paige M., Brennan, Paul, Brown, Elizabeth E., Burdett, Laurie, Cannon-Albright, Lisa A., Chang, Ellen T., Chiu, Brian C. H., Chung, Charles C., Clavel, Jacqueline, Cocco, Pierluigi, Colditz, Graham, Conde, Lucia, Conti, David V., Cox, David G., Curtin, Karen, Casabonne, Delphine, De Vivo, Immaculata, Diepstra, Arjan, Diver, W. Ryan, Dogan, Ahmet, Edlund, Christopher K., Foretova, Lenka, Fraumeni, Jr, Joseph F., Gabbas, Attilio, Ghesquières, Hervé, Giles, Graham G., Glaser, Sally, Glenn, Martha, Glimelius, Bengt, Gu, Jian, Habermann, Thomas M., Haiman, Christopher A., Haioun, Corinne, Hofmann, Jonathan N., Holford, Theodore R., Holly, Elizabeth A., Hutchinson, Amy, Izhar, Aalin, Jackson, Rebecca D., Jarrett, Ruth F., Kaaks, Rudolph, Kane, Eleanor, Kolonel, Laurence N., Kong, Yinfei, Kraft, Peter, Kricker, Anne, Lake, Annette, Lan, Qing, Lawrence, Charles, Li, Dalin, Liebow, Mark, Link, Brian K., Magnani, Corrado, Maynadie, Marc, McKay, James, Melbye, Mads, Miligi, Lucia, Milne, Roger L., Molina, Thierry J., Monnereau, Alain, Montalvan, Rebecca, North, Kari E., Novak, Anne J., Onel, Kenan, Purdue, Mark P., Rand, Kristin A., Riboli, Elio, Riby, Jacques, Roman, Eve, Salles, Gilles, Sborov, Douglas W., Severson, Richard K., Shanafelt, Tait D., Smith, Martyn T., Smith, Alexandra, Song, Kevin W., Song, Lei, Southey, Melissa C., Spinelli, John J., Staines, Anthony, Stephens, Deborah, Sutherland, Heather J., Tkachuk, Kaitlyn, Thompson, Carrie A., Tilly, Hervé, Tinker, Lesley F., Travis, Ruth C., Turner, Jenny, Vachon, Celine M., Vajdic, Claire M., Van Den Berg, Anke, Van Den Berg, David J., Vermeulen, Roel C. H., Vineis, Paolo, Wang, Sophia S., Weiderpass, Elisabete, Weiner, George J., Weinstein, Stephanie, Doo, Nicole Wong, Ye, Yuanqing, Yeager, Meredith, Yu, Kai, Zeleniuch-Jacquotte, Anne, Zhang, Yawei, Zheng, Tongzhang, Ziv, Elad, Sampson, Joshua, Chatterjee, Nilanjan, Offit, Kenneth, Cozen, Wendy, Wu, Xifeng, Cerhan, James R., Chanock, Stephen J., Slager, Susan L., and Rothman, Nathaniel

Published
2023
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57. Salt intake and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project

Author

Morais, Samantha, Costa, Adriana, Albuquerque, Gabriela, Araújo, Natália, Pelucchi, Claudio, Rabkin, Charles S., Liao, Linda M., Sinha, Rashmi, Zhang, Zuo-Feng, Hu, Jinfu, Johnson, Kenneth C., Palli, Domenico, Ferraroni, Monica, Bonzi, Rossella, Yu, Guo-Pei, López-Carrillo, Lizbeth, Malekzadeh, Reza, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson Shigueaki, Zaridze, David, Maximovitch, Dmitry, Vioque, Jesus, de la Hera, Manoli García, Moreno, Victor, Vanaclocha-Espi, Mercedes, Ward, Mary H., Pakseresht, Mohammadreza, Hernández-Ramirez, Raúl Ulises, López-Cervantes, Malaquias, Pourfarzi, Farhad, Mu, Lina, Kurtz, Robert C., Boccia, Stefania, Pastorino, Roberta, Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Camargo, M. Constanza, Curado, Maria Paula, Negri, Eva, La Vecchia, Carlo, and Lunet, Nuno

Published
2022
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58. Incidence, risk and protective factors of symptoms after colonoscopy

Author

Collatuzzo, Giulia, Boffetta, Paolo, Radaelli, Franco, Cadoni, Sergio, Hassan, Cesare, Frazzoni, Leonardo, Anderloni, Andrea, Laterza, Liboria, La Marca, Marina, Rogai, Francesca, Binda, Cecilia, Montale, Amedeo, Soriani, Paola, Fabbri, Carlo, Sacco, Marco, Gallittu, Paolo, Mura, Donatella, Trovato, Cristina, Vitale, Giovanna, Mussetto, Alessandro, Musso, Alessandro, Conti, Clara Benedetta, Manno, Mauro, Repici, Alessandro, Zagari, Rocco Maurizio, Farioli, Andrea, and Fuccio, Lorenzo

Published
2022
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59. Genetic overlap between autoimmune diseases and non‐Hodgkin lymphoma subtypes

Author

Din, Lennox, Sheikh, Mohammad, Kosaraju, Nikitha, Smedby, Karin Ekstrom, Bernatsky, Sasha, Berndt, Sonja I, Skibola, Christine F, Nieters, Alexandra, Wang, Sophia, McKay, James D, Cocco, Pierluigi, Maynadié, Marc, Foretová, Lenka, Staines, Anthony, Mack, Thomas M, de Sanjosé, Silvia, Vyse, Timothy J, Padyukov, Leonid, Monnereau, Alain, Arslan, Alan A, Moore, Amy, Brooks‐Wilson, Angela R, Novak, Anne J, Glimelius, Bengt, Birmann, Brenda M, Link, Brian K, Stewart, Carolyn, Vajdic, Claire M, Haioun, Corinne, Magnani, Corrado, Conti, David V, Cox, David G, Casabonne, Delphine, Albanes, Demetrius, Kane, Eleanor, Roman, Eve, Muzi, Giacomo, Salles, Gilles, Giles, Graham G, Adami, Hans‐Olov, Ghesquières, Hervé, De Vivo, Immaculata, Clavel, Jacqueline, Cerhan, James R, Spinelli, John J, Hofmann, Jonathan, Vijai, Joseph, Curtin, Karen, Costenbader, Karen H, Onel, Kenan, Offit, Kenneth, Teras, Lauren R, Morton, Lindsay, Conde, Lucia, Miligi, Lucia, Melbye, Mads, Ennas, Maria Grazia, Liebow, Mark, Purdue, Mark P, Glenn, Martha, Southey, Melissa C, Din, Morris, Rothman, Nathaniel, Camp, Nicola J, Doo, Nicole Wong, Becker, Nikolaus, Pradhan, Nisha, Bracci, Paige M, Boffetta, Paolo, Vineis, Paolo, Brennan, Paul, Kraft, Peter, Lan, Qing, Severson, Richard K, Vermeulen, Roel CH, Milne, Roger L, Kaaks, Rudolph, Travis, Ruth C, Weinstein, Stephanie J, Chanock, Stephen J, Ansell, Stephen M, Slager, Susan L, Zheng, Tongzhang, Zhang, Yawei, Benavente, Yolanda, Taub, Zachary, Madireddy, Lohith, Gourraud, Pierre‐Antoine, Oksenberg, Jorge R, Cozen, Wendy, Hjalgrim, Henrik, and Khankhanian, Pouya

Subjects
Biological Sciences, Genetics, Lymphoma, Arthritis, Neurodegenerative, Brain Disorders, Autoimmune Disease, Cancer, Human Genome, Rare Diseases, Hematology, Aetiology, 2.1 Biological and endogenous factors, Inflammatory and immune system, Alleles, Autoimmune Diseases, Female, Genetic Predisposition to Disease, HLA Antigens, Humans, Lymphoma, Non-Hodgkin, Male, Middle Aged, Multifactorial Inheritance, Polymorphism, Single Nucleotide, Risk Factors, autoimmune disease, genome-wide association study, meta-analysis, non-Hodgkin lymphoma, Public Health and Health Services, Epidemiology
Abstract

Epidemiologic studies show an increased risk of non-Hodgkin lymphoma (NHL) in patients with autoimmune disease (AD), due to a combination of shared environmental factors and/or genetic factors, or a causative cascade: chronic inflammation/antigen-stimulation in one disease leads to another. Here we assess shared genetic risk in genome-wide-association-studies (GWAS). Secondary analysis of GWAS of NHL subtypes (chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma, and marginal zone lymphoma) and ADs (rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis). Shared genetic risk was assessed by (a) description of regional genetic of overlap, (b) polygenic risk score (PRS), (c)"diseasome", (d)meta-analysis. Descriptive analysis revealed few shared genetic factors between each AD and each NHL subtype. The PRS of ADs were not increased in NHL patients (nor vice versa). In the diseasome, NHLs shared more genetic etiology with ADs than solid cancers (p = .0041). A meta-analysis (combing AD with NHL) implicated genes of apoptosis and telomere length. This GWAS-based analysis four NHL subtypes and three ADs revealed few weakly-associated shared loci, explaining little total risk. This suggests common genetic variation, as assessed by GWAS in these sample sizes, may not be the primary explanation for the link between these ADs and NHLs.

Published
2019

60. Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: A bivariate spline model approach

Author

Di Credico, Gioia, Edefonti, Valeria, Polesel, Jerry, Pauli, Francesco, Torelli, Nicola, Serraino, Diego, Negri, Eva, Luce, Daniele, Stucker, Isabelle, Matsuo, Keitaro, Brennan, Paul, Vilensky, Marta, Fernandez, Leticia, Curado, Maria Paula, Menezes, Ana, Daudt, Alexander W, Koifman, Rosalina, Wunsch-Filho, Victor, Holcatova, Ivana, Ahrens, Wolfgang, Lagiou, Pagona, Simonato, Lorenzo, Richiardi, Lorenzo, Healy, Claire, Kjaerheim, Kristina, Conway, David I, Macfarlane, Tatiana V, Thomson, Peter, Agudo, Antonio, Znaor, Ariana, Rios, Leonardo F Boaventura, Toporcov, Tatiana N, Franceschi, Silvia, Herrero, Rolando, Muscat, Joshua, Olshan, Andrew F, Zevallos, Jose P, La Vecchia, Carlo, Winn, Deborah M, Sturgis, Erich M, Li, Guojun, Fabianova, Eleonora, Lissowska, Jolanda, Mates, Dana, Rudnai, Peter, Shangina, Oxana, Swiatkowska, Beata, Moysich, Kirsten, Zhang, Zuo-Feng, Morgenstern, Hal, Levi, Fabio, Smith, Elaine, Lazarus, Philip, Bosetti, Cristina, Garavello, Werner, Kelsey, Karl, McClean, Michael, Ramroth, Heribert, Chen, Chu, Schwartz, Stephen M, Vaughan, Thomas L, Zheng, Tongzhang, Menvielle, Gwenn, Boccia, Stefania, Cadoni, Gabriella, Hayes, Richard B, Purdue, Mark, Gillison, Maura, Schantz, Stimson, Yu, Guo-Pei, Brenner, Hermann, D'Souza, Gypsyamber, Gross, Neil D, Chuang, Shu-Chun, Boffetta, Paolo, Hashibe, Mia, Lee, Yuan-Chin Amy, and Dal Maso, Luigino

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Prevention, Tobacco Smoke and Health, Substance Misuse, Tobacco, Dental/Oral and Craniofacial Disease, Rare Diseases, Cancer, 2.2 Factors relating to the physical environment, Good Health and Well Being, Adult, Aged, Aged, 80 and over, Case-Control Studies, Cigarette Smoking, Female, Head and Neck Neoplasms, Humans, Male, Middle Aged, Risk Factors, Bivariate spline models, Cigarette smoking duration, Cigarette smoking intensity, Head and neck cancer, INHANCE, Laryngeal cancer, Oral cavity and pharyngeal cancers, Dentistry, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

ObjectivesThis study aimed at re-evaluating the strength and shape of the dose-response relationship between the combined (or joint) effect of intensity and duration of cigarette smoking and the risk of head and neck cancer (HNC). We explored this issue considering bivariate spline models, where smoking intensity and duration were treated as interacting continuous exposures.Materials and methodsWe pooled individual-level data from 33 case-control studies (18,260 HNC cases and 29,844 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium. In bivariate regression spline models, exposures to cigarette smoking intensity and duration (compared with never smokers) were modeled as a linear piecewise function within a logistic regression also including potential confounders. We jointly estimated the optimal knot locations and regression parameters within the Bayesian framework.ResultsFor oral-cavity/pharyngeal (OCP) cancers, an odds ratio (OR) >5 was reached after 30 years in current smokers of ∼20 or more cigarettes/day. Patterns of OCP cancer risk in current smokers differed across strata of alcohol intensity. For laryngeal cancer, ORs >20 were found for current smokers of ≥20 cigarettes/day for ≥30  years. In former smokers who quit ≥10  years ago, the ORs were approximately halved for OCP cancers, and ∼1/3 for laryngeal cancer, as compared to the same levels of intensity and duration in current smokers.ConclusionReferring to bivariate spline models, this study better quantified the joint effect of intensity and duration of cigarette smoking on HNC risk, further stressing the need of smoking cessation policies.

Published
2019

61. Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study

Author

Brenner, Darren R, Fehringer, Gord, Zhang, Zuo-Feng, Lee, Yuan-Chin Amy, Meyers, Travis, Matsuo, Keitaro, Ito, Hidemi, Vineis, Paolo, Stucker, Isabelle, Boffetta, Paolo, Brennan, Paul, Christiani, David C, Diao, Nancy, Hong, Yun-Chul, Landi, Maria T, Morgenstern, Hal, Schwartz, Ann G, Rennert, Gad, Saliba, Walid, McLaughlin, John R, Harris, Curtis C, Orlow, Irene, Dios, Juan M Barros, Raviña, Alberto Ruano, Siemiatycki, Jack, Koushik, Anita, Cote, Michele, Lazarus, Philip, Fernandez-Tardon, Guillermo, Tardon, Adonina, Le Marchand, Loïc, Brenner, Hermann, Saum, Kai-Uwe, Duell, Eric J, Andrew, Angeline S, Consonni, Dario, Olsson, Ann, Hung, Rayjean J, and Straif, Kurt

Subjects
Biomedical and Clinical Sciences, Epidemiology, Health Sciences, Public Health, Oncology and Carcinogenesis, Cancer, Alcoholism, Alcohol Use and Health, Lung Cancer, Lung, Prevention, Substance Misuse, 2.2 Factors relating to the physical environment, Aetiology, Stroke, Good Health and Well Being, Adenocarcinoma, Aged, Alcohol Drinking, Alcoholic Beverages, Carcinoma, Squamous Cell, Case-Control Studies, Cohort Studies, Female, Humans, Lung Neoplasms, Male, Middle Aged, Odds Ratio, Risk Factors, Surveys and Questionnaires, Alcohol, Lung cancer, Pooled analysis, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

BackgroundThere is inadequate evidence to determine whether there is an effect of alcohol consumption on lung cancer risk. We conducted a pooled analysis of data from the International Lung Cancer Consortium and the SYNERGY study to investigate this possible association by type of beverage with adjustment for other potential confounders.MethodsTwenty one case-control studies and one cohort study with alcohol-intake data obtained from questionnaires were included in this pooled analysis (19,149 cases and 362,340 controls). Adjusted odds ratios (OR) or hazard ratios (HR) with corresponding 95% confidence intervals (CI) were estimated for each measure of alcohol consumption. Effect estimates were combined using random or fixed-effects models where appropriate. Associations were examined for overall lung cancer and by histological type.ResultsWe observed an inverse association between overall risk of lung cancer and consumption of alcoholic beverages compared to non-drinkers, but the association was not monotonic. The lowest risk was observed for persons who consumed 10-19.9 g/day ethanol (OR vs. non-drinkers = 0.78; 95% CI: 0.67, 0.91), where 1 drink is approximately 12-15 g. This J-shaped association was most prominent for squamous cell carcinoma (SCC). The association with all lung cancer varied little by type of alcoholic beverage, but there were notable differences for SCC. We observed an association with beer intake (OR for ≥20 g/day vs nondrinker = 1.42; 95% CI: 1.06, 1.90).ConclusionsWhether the non-monotonic associations we observed or the positive association between beer drinking and squamous cell carcinoma reflect real effects await future analyses and insights about possible biological mechanisms.

Published
2019

73. Improvement of esophageal cancer survival in Northeast Iran: A two-decade journey in a high-risk, low- resource region.

Author

Nemati, Saeed, Islami, Farhad, Kamangar, Farin, Poustchi, Hossein, Roshandel, Gholamreza, Shakeri, Ramin, Domingues, Allison, Khoshnia, Masoud, Gharavi, Abdolsamad, Brennan, Paul, Abnet, Christian C., Dawsey, Sanford M., Boffetta, Paolo, Malekzadeh, Reza, and Sheikh, Mahdi

Subjects
PROPORTIONAL hazards models, RESOURCE-limited settings, PUBLIC health infrastructure, SURVIVAL rate, PROGNOSIS, ETHNICITY
Abstract

Background and objective: Two decades ago, an international initiative (GEMINI) was launched in a high-risk, low-resource region in Northeast Iran, aiming to investigate incidence, etiology, early detection, and treatment of esophageal squamous cell carcinoma (ESCC). An earlier report from this area, highlighted poor ESCC survival rates, with a 5-year survival probability of 3.3% and the median survival time of 7 months. Our study assesses whether ESCC survival has improved since the implementation of the GEMINI initiative in this region. Material and methods: 490 adult patients with histologically-confirmed ESCC were recruited from the Atrak clinic, Golestan, Iran, between 2007 and 2018. At recruitment, information on demographics and various exposures were collected. Active (telephone surveys) and passive (linkage to Golestan population-based cancer and death registries) follow-up methods were used to determine patients' vital status though March 2019. Survival estimates were obtained by Kaplan-Meier method and Cox proportional hazards regression models. Results: Over the study period 340 deaths were recorded. Five-year ESCC survival probability was 23% (95% Confidence Interval: 19% to 28%), and the median survival time was 19 months. Five-year survival probability was higher among individuals who were younger (35% in <60-year-olds vs. 12% for >70-year-olds, p<0.001), educated (34% vs. 21% for no formal education, p = 0.027), never used opium (28% vs. 15%, p = 0.0016), and received cancer treatment (37% vs. 4%, p<0.001). In the adjusted models, a higher hazard of death was associated with older age [HR for each 10-year increase = 1.36 (95% CI = 1.22 to 1.51)], Turkman ethnicity [HR = 1.35 (95%CI: 1.07 to 1.70)], opium use [HR = 1.53 (95%CI: 1.20 to 1.94)],and receiving no cancer treatment [HR = 5.81 (95%CI: 3.97 to 8.52)]. Conclusion: Over the last two decades, ESCC survival in this population has significantly improved, highlighting the potential of enhancing healthcare infrastructure and ensuring access to affordable medical care in resource-limited, high-risk regions. Older age at diagnosis, Turkman ethnicity, opium use, and untreated cases (indicative of advanced disease at diagnosis) were identified as the main ESCC prognostic factors in this population. [ABSTRACT FROM AUTHOR]

Published
2024
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77. Application of two job indices for general occupational demands in a pooled analysis of case–control studies on lung cancer

Author

Hovanec, Jan, Siemiatycki, Jack, Conway, David I, Olsson, Ann, Guenel, Pascal, Luce, Danièle, Jöckel, Karl-Heinz, Pohlabeln, Hermann, Ahrens, Wolfgang, Karrasch, Stefan, Wichmann, Heinz-Erich, Gustavsson, Per, Consonni, Dario, Merletti, Franco, Richiardi, Lorenzo, Simonato, Lorenzo, Fortes, Cristina, Parent, Marie-Élise, McLaughlin, John R, Demers, Paul, Landi, Maria Teresa, Caporaso, Neil, Fernández-Tardón, Guillermo, Zaridze, David, Świątkowska, Beata, Pándics, Tamas, Lissowska, Jolanta, Fabianova, Eleonora, Field, John K, Mates, Dana, Bencko, Vladimir, Foretova, Lenka, Janout, Vladimir, Kromhout, Hans, Vermeulen, Roel, Boffetta, Paolo, Straif, Kurt, Schüz, Joachim, Casjens, Swaantje, Pesch, Beate, Brüning, Thomas, and Behrens, Thomas

Published
2021

79. Racial differences in the relationship between tobacco, alcohol, and the risk of head and neck cancer: pooled analysis of US studies in the INHANCE Consortium

Author

Voltzke, Kristin J, Lee, Yuan-Chin Amy, Zhang, Zuo-Feng, Zevallos, Jose P, Yu, Guo-Pei, Winn, Deborah M, Vaughan, Thomas L, Sturgis, Erich M, Smith, Elaine, Schwartz, Stephen M, Schantz, Stimson, Muscat, Joshua, Morgenstern, Hal, McClean, Michael, Li, Guojun, Lazarus, Philip, Kelsey, Karl, Gillison, Maura, Chen, Chu, Boffetta, Paolo, Hashibe, Mia, and Olshan, Andrew F

Subjects
Epidemiology, Biomedical and Clinical Sciences, Public Health, Health Sciences, Tobacco Smoke and Health, Rare Diseases, Dental/Oral and Craniofacial Disease, Alcoholism, Alcohol Use and Health, Substance Misuse, Prevention, Cancer, Clinical Research, Tobacco, Good Health and Well Being, Alcohol Drinking, Case-Control Studies, Head and Neck Neoplasms, Humans, Racial Groups, Risk Factors, Tobacco Use, United States, Head and neck cancer, Alcohol, Cigarette smoking, African American, Racial difference, Oncology and Carcinogenesis, Public Health and Health Services, Oncology and carcinogenesis
Abstract

There have been few published studies on differences between Blacks and Whites in the estimated effects of alcohol and tobacco use on the incidence of head and neck cancer (HNC) in the United States. Previous studies have been limited by small numbers of Blacks. Using pooled data from 13 US case-control studies of oral, pharyngeal, and laryngeal cancers in the International Head and Neck Cancer Epidemiology Consortium, this study comprised a large number of Black HNC cases (n = 975). Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI) for several tobacco and alcohol consumption characteristics. Blacks were found to have consistently stronger associations than Whites for the majority of tobacco consumption variables. For example, compared to never smokers, Blacks who smoked cigarettes for > 30 years had an OR 4.53 (95% CI 3.22-6.39), which was larger than that observed in Whites (OR 3.01, 95% CI 2.73-3.33; pinteraction

Published
2018

80. Erratum to: Hepatocellular carcinoma detection: diagnostic performance of a simulated abbreviated MRI protocol combining diffusion-weighted and T1-weighted imaging at the delayed phase post gadoxetic acid

Author

Besa, Cecilia, Lewis, Sara, Pandharipande, Pari V, Chhatwal, Jagpreet, Kamath, Amita, Cooper, Nancy, Knight-Greenfield, Ashley, Babb, James S, Boffetta, Paolo, Padron, Norma, Sirlin, Claude B, and Taouli, Bachir

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Nuclear Medicine & Medical Imaging, Clinical sciences
Published
2018

81. Impact of oral hygiene on head and neck cancer risk in a Chinese population

Author

Kawakita, Daisuke, Lee, Yuan‐Chin Amy, Li, Qian, Chen, Yuji, Chen, Chien‐Jen, Hsu, Wan‐Lun, Lou, Pei‐Jen, Zhu, Cairong, Pan, Jian, Shen, Hongbing, Ma, Hongxia, Cai, Lin, He, Baochang, Wang, Yu, Zhou, Xiaoyan, Ji, Qinghai, Zhou, Baosen, Wu, Wei, Ma, Jie, Boffetta, Paolo, Zhang, Zuo‐Feng, Dai, Min, and Hashibe, Mia

Subjects
Rare Diseases, Cancer, Dental/Oral and Craniofacial Disease, Clinical Research, Prevention, Oral and gastrointestinal, Adult, Age Distribution, Aged, Aged, 80 and over, Carcinoma, Squamous Cell, Case-Control Studies, China, Confidence Intervals, Female, Head and Neck Neoplasms, Humans, Incidence, Logistic Models, Male, Middle Aged, Multivariate Analysis, Neoplasm Invasiveness, Neoplasm Staging, Odds Ratio, Oral Hygiene, Risk Assessment, Sex Distribution, Young Adult, Chinese, dental care, head and neck cancer, oral hygiene, risk, Clinical Sciences, Dentistry, Otorhinolaryngology
Abstract

BackgroundAlthough the impact of oral hygiene on head and neck cancer risk has been investigated, few studies have been conducted among the Asian population.MethodsWe conducted a multicenter case-control study to investigate this potential association. We performed unconditional multiple logistic regression models adjusted by potential confounders.ResultsWe observed an inverse association of frequency of dental visits with head and neck cancer risk, with an adjusted odds ratio (OR) of 3.70 (95% CI 2.51-5.45) for never dental visits compared with ≥1 time/year (Ptrend < .001). We also observed a positive association between the number of missing teeth and head and neck cancer risk, with an adjusted OR for ≥5 missing teeth compared with

Published
2017

82. Dietary fiber intake and head and neck cancer risk: A pooled analysis in the International Head and Neck Cancer Epidemiology consortium

Author

Kawakita, Daisuke, Lee, Yuan‐Chin Amy, Turati, Federica, Parpinel, Maria, Decarli, Adriano, Serraino, Diego, Matsuo, Keitaro, Olshan, Andrew F, Zevallos, Jose P, Winn, Deborah M, Moysich, Kirsten, Zhang, Zuo‐Feng, Morgenstern, Hal, Levi, Fabio, Kelsey, Karl, McClean, Michael, Bosetti, Cristina, Garavello, Werner, Schantz, Stimson, Yu, Guo‐Pei, Boffetta, Paolo, Chuang, Shu‐Chun, Hashibe, Mia, Ferraroni, Monica, La Vecchia, Carlo, and Edefonti, Valeria

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Dental/Oral and Craniofacial Disease, Prevention, Cancer, Rare Diseases, Digestive Diseases, Oral and gastrointestinal, Good Health and Well Being, Adult, Aged, Alcohol Drinking, Carcinoma, Squamous Cell, Case-Control Studies, Dietary Fiber, Female, Head and Neck Neoplasms, Humans, Laryngeal Neoplasms, Male, Middle Aged, Pharyngeal Neoplasms, Risk Factors, Squamous Cell Carcinoma of Head and Neck, Tobacco, dietary fiber intake, INHANCE, head and neck cancer, laryngeal cancer, oral cavity and pharyngeal cancer, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

The possible role of dietary fiber in the etiology of head neck cancers (HNCs) is unclear. We used individual-level pooled data from ten case-control studies (5959 cases and 12,248 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium, to examine the association between fiber intake and cancer of the oral cavity/pharynx and larynx. Odds Ratios (ORs) and their 95% Confidence Intervals (CIs) were estimated using unconditional multiple logistic regression applied to quintile categories of non-alcohol energy-adjusted fiber intake and adjusted for tobacco and alcohol use and other known or putative confounders. Fiber intake was inversely associated with oral and pharyngeal cancer combined (OR for 5th vs. 1st quintile category = 0.49, 95% CI: 0.40-0.59; p for trend

Published
2017

85. The association between dietary fiber intake and gastric cancer: a pooled analysis of 11 case–control studies

Author

Collatuzzo, Giulia, primary, Cortez Lainez, Jacqueline, additional, Pelucchi, Claudio, additional, Negri, Eva, additional, Bonzi, Rossella, additional, Palli, Domenico, additional, Ferraroni, Monica, additional, Zhang, Zuo-Feng, additional, Yu, Guo-Pei, additional, Lunet, Nuno, additional, Morais, Samantha, additional, López-Carrillo, Lizbeth, additional, Zaridze, David, additional, Maximovitch, Dmitry, additional, Guevara, Marcela, additional, Santos-Sanchez, Vanessa, additional, Vioque, Jesus, additional, Garcia de la Hera, Manoli, additional, Ward, Mary H., additional, Malekzadeh, Reza, additional, Pakseresht, Mohammadreza, additional, Hernández-Ramírez, Raúl Ulises, additional, Turati, Federica, additional, Rabkin, Charles S., additional, Liao, Linda M., additional, Sinha, Rashmi, additional, López-Cervantes, Malaquias, additional, Tsugane, Shoichiro, additional, Hidaka, Akihisa, additional, Camargo, M. Constanza, additional, Curado, Maria Paula, additional, Zubair, Nadia, additional, Kristjansson, Dana, additional, Shah, Shailja, additional, La Vecchia, Carlo, additional, and Boffetta, Paolo, additional

Published
2024
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87. Supplementary Methods and Materials from Unveiling an Association between Waterpipe Smoking and Bladder Cancer Risk: A Multicenter Case–Control Study in Iran

Author

Hadji, Maryam, primary, Rashidian, Hamideh, primary, Marzban, Maryam, primary, Rezaianzadeh, Abbas, primary, Ansari-Moghaddam, Alireza, primary, Bakhshi, Mahdieh, primary, Nejatizadeh, Azim, primary, Seyyedsalehi, Monireh Sadat, primary, Naghibzadeh-Tahami, Ahmad, primary, Haghdoost, AliAkbar, primary, Mohebbi, Elham, primary, Freedman, Neal D., primary, Malekzadeh, Reza, primary, Etemadi, Arash, primary, Kamangar, Farin, primary, Weiderpass, Elisabete, primary, Pukkala, Eero, primary, Boffetta, Paolo, primary, and Zendehdel, Kazem, primary

Published
2024
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88. Dietary intake of copper and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project

Author

Sassano, Michele, primary, Collatuzzo, Giulia, additional, Seyyedsalehi, Monireh Sadat, additional, Pelucchi, Claudio, additional, Bonzi, Rossella, additional, Palli, Domenico, additional, Ferraroni, Monica, additional, Lunet, Nuno, additional, Morais, Samantha, additional, López-Carrillo, Lizbeth, additional, Malekzadeh, Reza, additional, Pakseresht, Mohammadreza, additional, López-Cervantes, Malaquias, additional, Ward, Mary H, additional, Camargo, Maria Constanza, additional, Curado, Maria Paula, additional, Vioque, Jesùs, additional, Zhang, Zuo-Feng, additional, Boccia, Stefania, additional, Negri, Eva, additional, La Vecchia, Carlo, additional, and Boffetta, Paolo, additional

Published
2024
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89. Data from Unveiling an Association between Waterpipe Smoking and Bladder Cancer Risk: A Multicenter Case–Control Study in Iran

Author

Hadji, Maryam, primary, Rashidian, Hamideh, primary, Marzban, Maryam, primary, Rezaianzadeh, Abbas, primary, Ansari-Moghaddam, Alireza, primary, Bakhshi, Mahdieh, primary, Nejatizadeh, Azim, primary, Seyyedsalehi, Monireh Sadat, primary, Naghibzadeh-Tahami, Ahmad, primary, Haghdoost, AliAkbar, primary, Mohebbi, Elham, primary, Freedman, Neal D., primary, Malekzadeh, Reza, primary, Etemadi, Arash, primary, Kamangar, Farin, primary, Weiderpass, Elisabete, primary, Pukkala, Eero, primary, Boffetta, Paolo, primary, and Zendehdel, Kazem, primary

Published
2024
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92. Association of female reproductive and hormonal factors with gallbladder cancer risk in Asia: A pooled analysis of the Asia Cohort Consortium

Author

Shin, Aesun, primary, Cho, Sooyoung, additional, Abe, Sarah Krull, additional, Islam, Md Rashedul, additional, Rahman, Md Shafiur, additional, Saito, Eiko, additional, Kazmi, Sayada Zartasha, additional, Katagiri, Ryoko, additional, Merritt, Melissa, additional, Choi, Ji‐Yeob, additional, Shu, Xiao‐Ou, additional, Sawada, Norie, additional, Tamakoshi, Akiko, additional, Koh, Woon‐Puay, additional, Sakata, Ritsu, additional, Hozawa, Atsushi, additional, Kim, Jeongseon, additional, Park, Sue K., additional, Kweon, Sun‐Seog, additional, Wen, Wanqing, additional, Tsugane, Shoichiro, additional, Kimura, Takashi, additional, Yuan, Jian‐Min, additional, Kanemura, Seiki, additional, Sugawara, Yumi, additional, Shin, Min‐Ho, additional, Ahsan, Habibul, additional, Boffetta, Paolo, additional, Chia, Kee Seng, additional, Matsuo, Keitaro, additional, Qiao, You‐Lin, additional, Rothman, Nathaniel, additional, Zheng, Wei, additional, Inoue, Manami, additional, and Kang, Daehee, additional

Published
2024
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