Search

Your search keyword '"Bernard, J.-L."' showing total 412 results
Start Over Author "Bernard, J.-L."
412 results on '"Bernard, J.-L."'

59. A homobimetallic vanadium d2–d2 complex (Cp2V)2(3η:4η-Me3SiCC–CC–CCSiMe3):structure and magnetism

Author

Bruno Donnadieu, Christian Lorber, Bernard J. L. Henner, Robert Choukroun, Richard Frantz, and Christian Guerin

Subjects
Magnetic moment, Magnetism, Inorganic chemistry, Metals and Alloys, Vanadium, chemistry.chemical_element, General Chemistry, Crystal structure, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Crystallography, chemistry, Materials Chemistry, Ceramics and Composites, Antiferromagnetism
Abstract

The d2–d2 homobimetallic complex (Cp2V)2(3η:4η-Me3-SiCC–CC–CCSiMe3) was synthesized from Me3SiCC–CC–CCSiMe3 and Cp2V and characterized by an X-ray crystal structure; magnetic moment measurements from 300 to 2 K indicated a weak antiferromagnetic J exchange coupling of –3.7 cm–1.

Published
1999

63. ChemInform Abstract: Pentacoordinated Silicon Anions: Synthesis and Reactivity

Author

Corriu Robert, W. W. C. Wong Chi Man, Bernard J. L. Henner, J.L. Brefort, and Christian Guerin

Subjects
Silicon, Chemistry, chemistry.chemical_element, Reactivity (chemistry), General Medicine, Medicinal chemistry
Abstract

Synthese des complexes Ph 3 Si(OMe) 2 − K + (18-crown-6), Ph 2 Si(OMe) 3 K + (18-crown-6), Ph 3 SiF 2 − K + (18-crown-6) et MePhSiF 3 − K + (18-crown-6) a partir de K.F (18-crown-6) et de Ph 3 SiF ou MePhSiF 2 , de KOMe (18-crown-6) et de Ph n Si(OMe) 4-n (n=1, 2 ou 3). Etude de la reactivite de ces complexes vis-a-vis de nucleophiles (RMgX, RLi, ROLi, LiAlH 4 )

Published
1990

69. Improving survival in recurrent medulloblastoma: earlier detection, better treatment or still an impasse?

Author

Bouffet, E, Doz, F, Demaille, M C, Tron, P, Roche, Henri, Plantaz, D, Thyss, Antoine, Stephan, J L, Lejars, O, Sariban, Eric, Buclon, M, Zucker, J M, Brunat-Mentigny, M, Bernard, J L, Gentet, J C, Bouffet, E, Doz, F, Demaille, M C, Tron, P, Roche, Henri, Plantaz, D, Thyss, Antoine, Stephan, J L, Lejars, O, Sariban, Eric, Buclon, M, Zucker, J M, Brunat-Mentigny, M, Bernard, J L, and Gentet, J C

Abstract

Early detection of relapse has been advocated to improve survival in children with recurrent medulloblastoma. However, the prognostic factors and the longer term outcome of these patients remains unclear. Pattern of recurrences were analysed in three consecutive protocols of the Société Française d'Oncologie Pédiatrique (1985-91). A uniform surveillance programme including repeated lumbar puncture combined with computerized tomography (CT) or magnetic resonance imaging (MRI) scan was applied for all registered patients. Forty-six out of 116 patients had progressive or recurrent disease. The median time from diagnosis to recurrence was 10.5 months and 76% relapses occurred during the first 2 years. Seventeen patients had asymptomatic relapses that were detected by the surveillance protocol. Forty-one patients were treated at time of progression. Twenty-three responded to salvage therapy and 11 achieved a second complete remission. The median survival time after progression was 5 months (<1-41 months), and only two patients remained alive at time of follow-up. Length of survival is primarily related to some specific patterns of relapse (time from diagnosis to recurrence, circumstances of relapse, extent of relapse) and to the response to salvage therapy. No evidence of long-term benefit appeared from any form of treatment., Clinical Trial, Journal Article, Multicenter Study, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1998

70. Synthesis and X-ray Crystallographic Studies of Diacetylenic Molecules Bearing Triorganosilyl, Triorganostannyl, and Diorganophosphanyl Substituents. Investigation of Their Solid-State and Molten-State Polymerization

Author

Carré,, Francis, primary, Devylder, Nathalie, additional, Dutremez, Sylvain G., additional, Guérin, Christian, additional, Henner, Bernard J. L., additional, Jolivet, Agnès, additional, Tomberli, Véronique, additional, and Dahan, Françoise, additional

Published
2003
Full Text
View/download PDF

71. Ifosfamide and etoposide in childhood osteosarcoma. A phase II study of the French Society of Paediatric Oncology.

Author

Gentet, J C, Brunat-Mentigny, M, Demaille, M C, Pein, F, Avet-Loiseau, Herve, Berger, C, De Lumley, L, Pacquement, H, Schmitt, Christian, Sariban, Eric, Pillon, P, Bernard, J L, Kalifa, C, Gentet, J C, Brunat-Mentigny, M, Demaille, M C, Pein, F, Avet-Loiseau, Herve, Berger, C, De Lumley, L, Pacquement, H, Schmitt, Christian, Sariban, Eric, Pillon, P, Bernard, J L, and Kalifa, C

Abstract

The aim of this phase II study was to determine the efficacy of high-dose ifosfamide with moderate dose etoposide in childhood osteosarcoma. From January 1992 to January 1995, 27 children (15 male, 12 female) with relapsed or refractory evaluable osteosarcoma were included in a phase II study of two courses of ifosfamide 3g/m2/day and etoposide 75 mg/m2/day for 4 days. Median age was 14 years (7-19 years). All but one had received high-dose methotrexate and doxorubicin as first-line treatment. 22 patients had previously received ifosfamide. This regimen was given as first-line in 1 patient, second-line in 23 and third-line in 3. Evaluable disease was lung metastases in 21 patients, local relapse in 5 and adenopathy in 1. There were six complete responses, seven partial responses, three minor responses, six stable disease and five progressive disease (including one mixed response). Response rate was 48% (95% confidence interval, 29-67%). Duration of response was not available (10 responding patients had other treatments). Response rate was equivalent in the subgroup of 22 patients who had previously received ifosfamide (4 CR, 6 PR). Among 3 patients who received the phase II regimen as third-line chemotherapy, there was 1 PR. All but 4 patients had a well tolerated grade 4 neutropenia. Transient mild confusion or seizures were each observed once. 5 patients are alive 15-31 months after the beginning of chemotherapy. This combination of drugs at this dosage has tolerable toxicity, is efficient and deserves evaluation in phase III studies., Clinical Trial, Clinical Trial, Phase II, Journal Article, Research Support, Non-U.S. Gov't, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
1997

72. Homobimetallic vanadium d1–d1 complexes: structure and magnetism

Author

Isabelle Malfant, Robert Choukroun, Richard Frantz, Christian Guerin, Simone Haubrich, Bernard J. L. Henner, and Bruno Donnadieu

Subjects
Magnetic moment, Magnetism, Inorganic chemistry, Metals and Alloys, Vanadium, chemistry.chemical_element, General Chemistry, Crystal structure, Vanadocene, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Crystallography, chemistry.chemical_compound, chemistry, Materials Chemistry, Ceramics and Composites, Antiferromagnetism
Abstract

From Me3SiCC–CCSiMe3 and Ph2PCC–CCPPh2 diynes and vanadocene VCp2, homobimetallic vanadium d1–d1 complexes are synthesized and characterized by X-ray crystal structures of (Cp2V)2(1-2η:3-4η-RCC–CCR), (R = SiMe3 1 PPh2 2); magnetic moments of both complexes from 300 to 2 K indicate an antiferromagnetic J exchange coupling of –10.5 and –59.8 cm–1 for 1 and 2, respectively.

Published
1997

74. Exploratory Studies on the Synthesis of Unsymmetrically Substituted Diacetylenes Bearing Trialkoxysilyl Groups and Development of a Method for the Preparation of 1-Lithio-4-(2,8,9-trioxa-5-aza-1-silabicyclo[3.3.3]undecanyl)-1,3-butadiyne: Synthetic and Mechanistic Aspects

Author

Brunel, Luc, primary, Chaplais, Gérald, additional, Dutremez, Sylvain G., additional, Guérin, Christian, additional, Henner, Bernard J. L., additional, and Tomberli, Véronique, additional

Published
2000
Full Text
View/download PDF

77. An open-label, multicentre, randomised phase 2 study of recombinant human granulocyte colony-stimulating factor (filgrastim) as an adjunct to combination chemotherapy in paediatric patients with metastatic neuroblastoma

Author

Michon, J.M, primary, Hartmann, O, additional, Bouffet, E, additional, Meresse, V, additional, Coze, C, additional, Rubie, H, additional, Bordigoni, P, additional, Cattiaux, E, additional, Ward, N, additional, Bernard, J.-L, additional, Lemerle, J, additional, Zucker, J.-M, additional, and Philip, T, additional

Published
1998
Full Text
View/download PDF

78. NB87 induction protocol for stage 4 neuroblastoma in children over 1 year of age: a report from the French Society of Pediatric Oncology.

Author

Coze, C, primary, Hartmann, O, additional, Michon, J, additional, Frappaz, D, additional, Dusol, F, additional, Rubie, H, additional, Plouvier, E, additional, Leverger, G, additional, Bordigoni, P, additional, Béhar, C, additional, Beck, D, additional, Mechinaud, F, additional, Bergeron, C, additional, Plantaz, D, additional, Otten, J, additional, Zucker, J M, additional, Philip, T, additional, and Bernard, J L, additional

Published
1997
Full Text
View/download PDF

79. Organosilicon polymers: synthesis of poly[(silanylene)diethynylene]s with conducting properties

Author

Thomas Kuhlmann, Bernard J. L. Henner, Christian Guerin, Francis Garnier, Robert J. P. Corriu, Alain Jean, and A. Yassar

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Materials science, Polymer science, chemistry, General Chemical Engineering, Materials Chemistry, Organic chemistry, General Chemistry, Polymer, Organosilicon
Published
1990

80. Preirradiation chemotherapy including “eight drugs in 1 day” regimen and high-dose methotrexate in childhood medulloblastoma: results of the M7 French Cooperative Study

Author

Gentet, J. C., primary, Bouffet, E., additional, Doz, F., additional, Tron, P., additional, Roche, H., additional, Thyss, A., additional, Plantaz, D., additional, Stephan, J. L., additional, Mottolese, C., additional, Ponvert, D., additional, Carrie, C., additional, Raybaud, C., additional, Brunat-Mentigny, M., additional, Choux, M., additional, Philip, T., additional, Zucker, J. M., additional, and Bernard, J. L., additional

Published
1995
Full Text
View/download PDF

89. Pragmatic aspects of communication and language in typical children and in children later diagnosed with autism.

Author

Guidetti, M., Turquois, L., Adrien, J.-L., Barthélémy, C., and Bernard, J.-L.

Subjects
COMMUNICATION, AUTISM, AUTISM in children, COMMUNICATIVE disorders, HOME movies
Abstract

Copyright of Psychologie Française is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2004
Full Text
View/download PDF

92. Phenotyping of intrahepatic and peripheral blood lymphocytes in patients with chronic hepatitis C.

Author

Tran, A, Yang, G, Doglio, A, Ticchioni, M, Laffont, C, Durant, J, Bernard, J L, Gugenheim, J, Saint-Paul, M C, Bernard, A, Rampal, P, and Benzaken, S

Abstract

The host immune responses have been suggested to play a role in liver injury occurring in patients with chronic hepatitis C. In order to explore the relationship between the relative proportions of intrahepatic and peripheral blood lymphocytes (IHL, PBL), the levels of viremia, and the histological hepatitis activity score, three-color fluorescence-activated cytometric analysis was performed for 36 patients with chronic hepatitis C and six control subjects without chronic hepatitis. The liver biopsy was performed before any antiviral therapy. Each liver specimen was divided into two parts: one for histological examination and one for immunological analysis. Tricolor CD45 was used to improve "lymphogating." Fluorescein isothiocyanate- or phycoerythrin-conjugated monoclonal antibodies with specificity for CD3, CD4, CD8, and CD20 (lymphocyte subpopulations), for CD69 (activated lymphocytes), and for CD16/56 (natural killer cells) were used. The livers of patients with chronic hepatitis C contained a greater proportion of CD4+ lymphocytes that exhibited marked expression of CD69 than in control subjects (20.7 +/- 7.3% vs 10.2 +/- 4.6%, P = 0.027). Moreover, in patients with chronic hepatitis C, the proportion of CD4+ IHL correlated with the histological hepatitis activity evaluated by the Knodell score (r = 0.48, P = 0.004). No correlation was found between the percentage of CD4+ IHL and the level of viremia or transaminase activities. Our findings clearly indicate that a cellular immune response does take place in HCV-infected livers and could thus contribute to the outcome of hepatitis C virus infection. [ABSTRACT FROM AUTHOR]

Published
1997

97. An Attribution Analysis of Jurors' Judgments in Civil Cases.

Author

Lupfer, Michael, Cohen, Robert, Bernard, J. L., Smalley, Dale, and Schippmann, Jeff

Subjects
COURT personnel, CRIMINAL justice personnel, REASONING, COLLEGE students, LEGAL judgments, BEHAVIOR
Abstract

Jurors' assessment of disputants in civil cases can be conceptualized as an attributional task. An experiment was designed to test the hypothesis that jurors, in the process of performing their attributional analyses of disputants, would exhibit judgmental biases that favor the defendant and disfavor the plaintiff. A total of 166 college students witnessed slide-tape presentations of trials for two civil cases. Each trial represented one condition in a 2 × 2 (Roles × Order) factorial design: Jurors (a) either heard Actors X and Y assume the roles of plaintiff and defendant or heard the same actors assume the opposite roles and (b) expressed their verdicts either before or after engaging in an attributional analysis of each litigant's behavior. The results supported the hypothesis. Juror's attributional analyses in both trials reflected a bias against the plaintiff. Each actor's behavior was attributed more often to hostile intentions and negative stereotypes when he assumed the role of plaintiff than when he was the defendant. Juror's verdicts also reflected a bias against the plaintiff, with votes for each actor in both trials decreasing as he shifted from defendant to plaintiff. No significant order effect was detected in either trial. [ABSTRACT FROM AUTHOR]

Published
1985
Full Text
View/download PDF

98. SOME EFFECTS OF A BRIEF COURSE IN THE PSYCHOLOGY OF ADJUSTMENT ON A PSYCHIATRIC ADMISSIONS WARD.

Author

Bernard, J. L., Kinzie, W. B., Tollman, G. A., and Webb, R. A.

Subjects
*PSYCHIATRIC hospital patients, *MENTAL health services, *PSYCHOLOGICAL adaptation, *GROUP psychotherapy, *PSYCHIATRY, *CLINICAL sociology
Abstract

The article presents information on some effects of a brief course in the psychology of adjustment on a psychiatric admissions ward. Group psychotherapy is an inadequate solution to the staggering patient load in the typical state hospital. The psychotherapy group begins to resemble a classroom with a teacher and pupils rather than a hospital with a therapist and patients. The data suggest that it is possible to influence pathological attitudes through the medium of a brief lecture series. The nonpsychotic controls showed a statistically significant reduction in somatic complaints.

Published
1965
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results