51. A simple technique for morphological measurement of cerebral arterial circle variations using public domain software (Osiris)
- Author
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J Mocco, Sarah Ganji, Shahab Kamali-Ardakani, Majid Dadmehr, Behzad Eftekhar, Brian L. Hoh, Douglas J. McConnell, Hassan Azari, and Saeed Ansari
- Subjects
Pathology ,medicine.medical_specialty ,Histology ,Anatomical structures ,Anatomical variation ,Cellular and Molecular Neuroscience ,Neurobiology ,medicine.artery ,Methods ,medicine ,Bilateral hypoplasia ,Posterior communicating artery ,Cerebral arterial circle ,Public domain software ,biology ,business.industry ,Cell Biology ,Anatomy ,biology.organism_classification ,Circle of Willis ,Original Article ,Osiris ,business ,Developmental Biology - Abstract
Th is article describes a straightforward method to measure the dimensions and identify morphological variations in the cerebral arterial circle using the general-purpose software program Osiris. This user-friendly and portable program displays, manipulates, and analyzes medical digital images, and it has the capability to determine morphometric properties of selected blood vessels (or other anatomical structures) in humans and animals. To ascertain morphometric variations in the cerebral arterial circle, 132 brains of recently deceased fetuses, infants, and adults were dissected. Th e dissection procedure was first digitized, and then the dimensions were measured with Osiris software. Measurements of each vessel's length and external diameters were used to identify and classify morphological variations in the cerebral arterial circle. The most commonly observed anatomical variations were uni- and bilateral hypoplasia of the posterior communicating artery. Th is study demonstrates that public domain soft ware can be used to measure and classify cerebral arterial circle vessels. Th is method could be extended to examine other anatomical regions or to study other animals. Additionally, knowledge of variations within the circle could be applied clinically to enhance diagnostic and treatment specifi city.
- Published
- 2011
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