586 results on '"Batinica A"'
Search Results
52. Increased Toll-like receptor 4 expression in infants with respiratory syncytial virus bronchiolitis
- Author
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GAGRO, A., TOMINAC, M., KRŠULOVIĆ-HREŠIĆ, V., BAĆE, A., MATIĆ, M., DRAŽENOVIĆ, V., MLINARIĆ-GALINOVIĆ, G., KOSOR, E., GOTOVAC, K., BOLANČA, I., BATINICA, S., and RABATIĆ, S.
- Published
- 2004
53. Bug or no bug: challenges in diagnosing cutaneous mycobacterial infections
- Author
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Georg Plum, Franziska Peters, Sabine A. Eming, Marina Batinica, and Mario Fabri
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medicine.medical_specialty ,Microbiological culture ,business.industry ,Cutaneous mycobacterial infections ,030231 tropical medicine ,Dermatology ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Effective treatment ,Differential diagnosis ,Medical diagnosis ,business ,Skin pathology - Abstract
Cutaneous mycobacterioses are rare in Germany. Nevertheless, early diagnosis and subsequent effective treatment requires awareness of these conditions. Moreover, mycobacterial infections are on the differential diagnosis list of many skin diseases. Diagnoses of cutaneous mycobacterioses are based on clinical features, but also on laboratory investigations, including bacterial culture, histopathology and PCR-based methods. Knowledge about the opportunities and limitations of theses laboratory tests is pivotal to reasonable clinical decision-making. In this paper, we review the current diagnostic options when suspecting a case of cutaneous mycobacterial infection.
- Published
- 2016
54. Clinical profile of adolescents with essential hypertension
- Author
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Helena Strizić, Vesna Herceg Čavrak, and Maja Batinica
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Pediatrics, Perinatology and Child Health - Published
- 2016
55. ANALIZA EKSTERNE OKOLINE PODUZEĆA IMPOL – TLM d.o.o. : Završni rad
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Batinica, Daria and Talaja, Anita
- Subjects
eksterna okolina ,Impol – TLM ,externalenvironment ,SOCIAL SCIENCES. Economics. Organization and Management ,interna okolina ,internalenvironment ,DRUŠTVENE ZNANOSTI. Ekonomija. Organizacija i menadžment - Abstract
U ovome radu obrađena je tema analize okoline poduzeća „Impol – TLM d.o.o.“ Da bi pobliže objasnili što je to točno okolina, trebamo prvenstveno definirati što je to menadžment i kakva je poveznica između njega i okoline. Menadžment možemo definirati kao proces, vještinu, znanstvenu disciplinu, profesiju ili funkciju u organizaciji, tj. nositelje određenih funkcija. Menadžment kao vještinu treba shvatiti kao sposobnost da se, više ili manje uspješno, obnašaju funkcije i uloge menadžmenta. Svatko tko u bilo kojoj organizaciji usmjerava posao drugih ljudi prema ostvarenju ciljeva organizacije može se zvati menadžerom. Okolina poduzeća je kompleksan pojam koji sadrži eksternu i internu okolinu. Eksternu okolinu poduzeća čine činitelji koji izvana utječu na poduzeće. Dijeli se na opću ili socijalnu okolinu i poslovnu okolinu ili okolinu zadatka. Opću ili socijalnu okolinu čine snage koje nisu pod utjecajem poduzeća, a trebamo ih promatrati i na njih reagirati. Poslovnu okolinu čine svi koji se nalaze u neposrednoj okolini poduzeća, a povezani su s njim. Poduzeće Impol – TLM se kroz ekonomska gledišta lako nosi s gospodarskom situacijom u zemlji, svi su ekonomski faktori zadovoljeni, te se poduzeće lako nosi s razvojem novih tehnologija koje utječu na poslovanje.Najveću prijetnju, ali ne i preveliku predstavljaju prirodna ili fizička okolina i socijalno – kulturna okolina o kojoj ovisi distribucija proizvoda koja je otežana u vremenskim neprilikama. Analizom poslovne okoline utvrđeno je kako najveći problem za poduzeće predstavljaju konkurenti i sindikati. Dobavljači i kupci su najbitniji segmenti i o njima najviše ovisi uspješnost poslovanja. SWOT analizom, došli smo do rezultata da poduzeće ima izražajnije interne snage i eksterne prilike u odnosu na interne slabosti i eksterne prijetnje. In this Bachelor Thesis, the Environmental Analysis of the company Impol-TLM d.o.o. has been processed. At first glance, we should define management so that the reader can better understand the term of environment itself. Management can be defined as the process, skill, science discipline, profession, or function within an organization, also known as “Holder of certain functions”. Management from a skill perspective should be considered as an aptitude observation of the functions and parts of the management. A manager can be proclaimed by any person that manages and leads other people’s business. Company environment is a complex term which contains both the external and internal einvironments. The external environment holds factors that have an impact on a company from the outside. It is divided in general or social environments, and business environment or environment of the tasks. General (or social) environement constitutes strengths that are not under supervision of the company, but should rather be observed and reacted by us in the most appropriate way. Business environment consists of any factor that is near proximity to the company and is related to it. Impol-TLM has been well surrounded by the economic situation of the country. All economic factors have been fullfilled and the company follows upcoming technologies that are related to its business. The biggest threat presents natural/or physical and socio-cultural environment which has an impact on distribution. The conclusion has been defined by the analysis of the business environment. The biggest problem for the company presents competition and trade unions. Suppliers and customers are the most important part, and because of them the success of the company is tenable. The SWOT analysis has provided results that show the company has more reliable internal strengths and external opportunities than the internal weaknesses and external threats.
- Published
- 2018
56. 05 / Interventional neuroradiology- the specific challenges for anesthesiologist
- Author
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Vladimir Kalousek, Lana Videc, and Inga Mladić Batinica
- Published
- 2018
57. 08 / Comparison of normal saline and balanced crystalloid intravenous therapy during neurosurgery
- Author
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Inga Mladić Batinica and Natasa Kovac
- Published
- 2018
58. Metal allergy as a late-onset complication of the Nuss procedure in a pediatric patient
- Author
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Irena Ivković-Jureković, Maja Batinica, and Marta Navratil
- Subjects
Pulmonary and Respiratory Medicine ,Hypersensitivity, Immediate ,Male ,medicine.medical_specialty ,Adolescent ,Late onset ,Nuss procedure ,Steel bar ,Metal allergy ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Pectus excavatum ,medicine ,Humans ,business.industry ,fungi ,Atopic diathesis ,Prostheses and Implants ,medicine.disease ,Stainless Steel ,Surgery ,Pediatric patient ,030220 oncology & carcinogenesis ,Funnel Chest ,Pediatrics, Perinatology and Child Health ,business ,Complication - Abstract
We report the case of a 14-year-old boy with pectus excavatum who developed a metal allergy to stainless steel bar as a late-onset complication after the Nuss procedure. He did not have atopic diathesis. Treatment with oral steroids was effective and the metal bar was successfully removed 2 years later.
- Published
- 2018
59. Povišeni troponin u djece i adolescenata sa zdravim srcem
- Author
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Vujnović, Katarina, Navratil, Marta, Mustapić, Željka, and Batinica, Maja
- Subjects
troponin ,djeca - Abstract
Uvod: Srčani troponini, prvenstveno upotrebljavani u dijagnostici akutnog koronarnog sindroma, osjetljivi su i specifi čni biomarkeri miokardijalne patnje - oslobađaju se u krvotok iz srčanih miocita, oštećenih akutnom ishemijom ili drugim mehanizmom. Osim miokardnog infarkta, povišenje troponina može nastati zbog brojnih drugih kliničkih stanja. Povišenje troponina upućuje na prisutnost, ali ne i na mehanizam miokardne ozljede. Patofi ziološki mehanizmi još nisu potpuno razjašnjeni i interpretacija nalaza, primjerice uz povišenje razine troponina nakon tjelesne aktivnosti, varira od dokaza miokardnog oštećenja induciranog aktivnošću do nevažnog, „lažnog“, povišenja troponina, vjerojatno uzrokovanog analitičkim interferencijama ili cirkulirajućim heterofi lnim protutijelima. Povišena vrijednost srčanog troponina, uz odsutnost kliničkih znakova ishemije, treba potaknuti pretrage za otkrivanje drugih uzroka miokardne patnje. Prikaz slučaja: Trinaestogodišnji dječak se prezentirao u hitnoj službi s boli u prsištu, blagom egzacerbacijom astme i povišenom razinom troponina I. (hsTnI = 255, 8 ; 575, 7 ng/L - ref. < 10, 0) nakon športske aktivnosti. Nakon prijma je liječen kratkodjelujućim beta-agonistima, našto je uslijedila potpuna regresija boli. Razina troponina postupno se normalizirala 48 sati nakon prijma. U daljnjem tijeku pacijent nije imao simptoma bolesti za 4-dnevne hospitalizacije, a ni drugih znakova ishemije miokarda. Parametri plućne funkcije su bili uredni. Dodatne pretrage jedan mjesec nakon hospitalizacije otkrile su umjerenu bronhalnu hiperreaktivnost nakon metakolinskog testa. Razina troponina i nalaz spirometrije bili su u granicama normale prije i nakon testa opterećenja (spiroergometrije). Slijedom prikaza pacijenta raspravlja se o diferencijalno-dijagnostičkim dvojbama u djece i adolescenata sa zdravim srcem, bez ozljede srca i s povišenom razinom troponina - utjecaj tjelesne/športske aktivnosti, akutne respiratorne insufi cijencije - egzacerbacije astme, tahikardije - što je sve bio slučaj u prikazanog pacijenta. Rasprava/zaključak: Premda se srčani troponini smatraju zlatnim standardom u dijagnosticiranju akutnog koronarnog sindroma, pogrješna interpretacija može voditi k neprimjerenim dijagnostičkim i terapijskim postupcima. Liječnici, osobito pedijatri kojima je takva problematika povremena, trebaju poznavati neishemijske uzroke povišenja troponina, kao i njihove patogenetske mehanizme te kliničko značenje, kako bi se spriječili nepotrebni daljnji dijagnostički i terapijski postupci, a da se pritom ne previde potencijalno životno ugrožavajuća stanja.
- Published
- 2018
60. Comparison of normal saline and balanced crystalloid intravenous therapy during neurosurgery
- Author
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Kovač, Nataša, Mladić Batinica, Inga, Kukin, Dijana, Murselović, Tamara, and Tonković Dinko
- Subjects
Neurosurgery, normal saline fluid, balanced fluid - Abstract
Normal saline or 0.9% NaCl solution is the most commonly used intravenous fluid worldwide and its composition are 154 mmol Na+ and 154 mmol Cl- per litter with osmolarity of 308 mOsmol/L. That composition is not “normal” because plasma contains sodium in range between 137-146 mmol/L, and chloride in range between 98-106 mmol/L, with plasma osmolality of 280- 295 mOsmol/kg. Recently published data suggested detrimental effects of chloride rich fluids on renal blood flow and glomerular filtration rate, urine output and acute kidney injury. One alternative to saline solution is a buffered, balanced, crystalloid solution with an electrolyte composition similar to plasma and osmolarity between 286-295 mOsmol/L. Someone could indicate that such balanced solutions are not suitable for neurosurgical patients because of a possible impact on the brain oedema development.
- Published
- 2018
61. Metal allergy as late-onset complication of the Nuss procedure in a pediatric patient
- Author
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Navratil M, Batinica M, Ivković-Jureković I
- Subjects
fungi ,Nuss procedure ,metal allergy ,pectus excavatum ,stainless steel ,titanium - Abstract
We report the case of a 14-year-old boy with pectus excavatum who developed a metal allergy to stainless steel bar as a late-onset complication after the Nuss procedure. He did not have atopic diathesis. Treatment with oral steroids was effective and the metal bar was successfully removed 2 years later.
- Published
- 2018
62. White matter anatomy relevant for glioma surgery in eloquent brain regions
- Author
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Tomislav Sajko, Krešimir Rotim, Marina Zmajević-Schoenwald, Inga Mladić-Batinica, and Svjetlana Salkičević
- Subjects
Glioma – complications, diagnosis, surgery ,White Matter – anatomy & histology ,Neurosurgery ,glioma – complications, diagnosis, surgery ,white matter – anatomy & histology ,neurosurgery - Abstract
Background: The primary aim of the glioma surgery is to achieve a balance between maximal tumor removal and minimal functional morbidity. The knowledge of morphology of the sulci, fissures, gyri and the white matter with its connecting fibers are crucial for successful resection. Material and methods: Fourteen patients had tumor lesions in close proximity to eloquent cortex, including primary motor and sensory cortex in either hemisphere and the language cortex in the dominant hemisphere. Patients underwent a thorough neuropsychological evaluation prior to surgery. Patients were kept fully awake during the whole surgical procedure. Brain mapping was performed by direct cortical stimulation using the Ojemann stimulator to identify a safe cor- ridor for surgical approach to the tumor. Intraoperative physiological monitoring was carried out by the assessment of speech, motor and sensory functions during the process of surgical resection. All resections were evaluated and verified by postoperative imaging. Postoperative complications and neurological deficits, as well as the extent of tumor resection, were evaluated. Results: Fourteen patients were operated due to tumor lesions in the primary motor cortex of the left hemisphere (glioma, metastatic tumor). Patients were fully collaborative during the cortical mapping. There were no perioperative complications. There was no deterioration of the neurological finding after the surgery. Conclusion: Subcortical stimulations remain the 'gold standard' when attempting to perform a complete resection together with a safe functional outcome.
- Published
- 2018
63. Intraoperacijska neurofiziologija i njezina uloga u sprječavanju poslijeoperacijskog deficita
- Author
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Marina Zmajević Schönwald, Krešimir Rotim, Tomislav Sajko, Inga Mladić-Batinica, and Svjetlana Salkičević
- Subjects
Neurofiziologija ,Intraoperacijsko neurofiziološko promatranje ,Poslijeoperacijske komplikacije ,neurofiziologija ,intraoperacijsko neurofiziološko promatranje ,poslijeoperacijske komplikacije - Abstract
U intraoperacijskoj neurofiziologiji razlicitim se neurofizioloskim tehnikama, koje su prila- godene operacijskim uvjetima, prikupljaju informacije o trenutacnom funkcioniranju struktura u operacijskome polju i/ili funkcioniranju onih inervacijskih (i irigacijskih) podrucja koja su u viskom riziku ostecenja zbog rada u operacijskom polju. Neurofizioloskim mapiranjem odredujemo anatomski smjestaj elokventnih mozdanih funkcionalnih regija, ukljucujuci i govor, te biranih neelokventnih funk- cionalnih regija u operacijskome polju. Mapiranjem se znacajne regije, bitne za kvalitetu zivota poslije operacije, mogu prepoznati u operacijskome polju i maksimalno postedjeti za vrijeme operacijskih postupaka ili intraoperacijske resekcije tkiva. Drugi smjer neurofizioloskoga djelovanja u operacijskoj sali jest intraoperacijsko monitori- ranje tj. kontinuirano pracenje funkcija aferentnih i eferentnih zivcanih putova od generiranja zivcanoga impulsa do njegove registracije za vrijeme operacije. U neurofizioloskome monitoriranju najcesce primjenjujemo sljedece modalitete: somatosenzoricke evocirane potencijale (SSEP), motoricke evocirane potencijale (MEP), kortikobulbame motoricke evocirane potencijale (CoMEP), slusne evocirane potencijale mozdanoga debla (BAEP), vidne evocirane potencijale (VEP), spontani EMG, elektroencefalogram (EEG) i elektrokortikografiju (ECoG). U praksi se uvijek primjenjuje multimodalno monitoriranje kako bi se intraoperacijski kontro- lirao veci broj ugrozenih mozdanih puteva. Kombinacija modaliteta ovisi o prijeoperacijskom statusu bolesnika, anamnezi, ucinjenoj dija- gnostici i ustanovljenim intraoperacijskim podrucjima rizika. Bas zbog toga od velikogje znacaja ozbiljno prijeoperacijski pregledati bolesnika te klinicki , , predvidjeti" rizicne ili ustanoviti vec djelomicno ostecene regije. Rad neurologa nastavlja se poslijeoperacijskim neuroloskim pregle- dom bolesnika unutar 24 sata nakon operacije te daljnjim neuroloskim pregledima i konzultaci- jama s rehabilitacijskim timom. Boravak u bolnici pacijenta zavrsava neuroloskim pregledom kod otpusta iz bolnice. Kontrole, osobito kod mogucih recidivirajucih patologija (recidivirajuci tumori) nastavljaju se ambulantno.
- Published
- 2018
64. Awake surgery for tumor sin eloquent brain region : first cases in Croatia
- Author
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Krešimir Rotim, Tomislav Sajko, Inga Mladić-Batinica, and Marina Zmajević-Schoenwald
- Subjects
Neurosurgery ,Brain Neoplasms – diagnosis ,Consciousness - Published
- 2018
65. Izbor anesteziološke tehnike za operacije tumora mozga u budnom stanju bolesnika
- Author
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Inga Mladić Batinica
- Subjects
Tumori mozga ,Neurokirurgija ,Anestezija ,Svjesnost - Published
- 2018
66. PSEUDOCHOLINESTERASE IN INFANTS WITH BILIARY LIVER CIRRHOSIS
- Author
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Popovic, Lj., Kunec- Vajic, E., Mazar, M., Colak, Z., Batinica, S., and Zupancic, B.
- Published
- 1997
67. Bilateral gonadoblastoma in a 9-month-old infant with 46,XY gonadal dysgenesis
- Author
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Dumić, M., Jukić, S., Batinica, S., Ille, J., and Filipović-Grc̆ić, B.
- Published
- 1993
- Full Text
- View/download PDF
68. Correlation of Merkel cell polyomavirus positivity with PDGFRα mutations and survivin expression in Merkel cell carcinoma
- Author
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Paola Zigrino, Cornelia Mauch, Baki Akgül, Steffi Silling, and M. Batinica
- Subjects
Male ,Receptor, Platelet-Derived Growth Factor alpha ,Skin Neoplasms ,Survivin ,Virus Integration ,Population ,Merkel cell polyomavirus ,Dermatology ,medicine.disease_cause ,Polymorphism, Single Nucleotide ,Biochemistry ,Virus ,Inhibitor of Apoptosis Proteins ,medicine ,Humans ,education ,Molecular Biology ,Aged ,education.field_of_study ,Mutation ,biology ,Merkel cell carcinoma ,food and beverages ,Viral Load ,Genes, p53 ,medicine.disease ,biology.organism_classification ,Carcinoma, Merkel Cell ,Disease Progression ,Cancer research ,Female ,Carcinogenesis ,Viral load - Abstract
Background Merkel cell carcinoma (MCC) is a neuroendocrine cancer of the skin postulated to originate through Merkel cell polyomavirus (MCPyV) oncogenesis and/or by mutations in molecules implicated in the regulation of cell growth and survival. Despite the fact that MCPvV is detected more broadly within the population, only a part of the infected people also develop MCC. It is thus conceivable that together, virus and for example mutations, are necessary for disease development. However, apart from a correlation between MCPyV positivity or mutations and MCC development, less is known about the association of these factors with progressive disease. Objectives To analyze MCPyV positivity, load and integration in MCC as well as presence of mutations in PDGFRα and TP53 genes and correlate these with clinical features and disease progression to identify features with prognostic value for clinical progression. Methods This is a study on a MCC population group of 64 patients. MCPyV positivity, load and integration in parallel to mutations in the PDGFRα and TP53 were analyzed on genomic DNA from MCC specimens. In addition, expression of PDGFRα, survivin and p53 proteins was analyzed by immunodetection in tissues specimens. All these parameters were analyzed as function of patient's disease progression status. Results 83% of MCCs were positive for the MCPyV and among these 36% also displayed virus-T integration. Viral load ranged from 0.006 to 943 viral DNA copies/β-globin gene and was highest in patients with progressive disease. We detected more than one mutation within the PDGFRα gene and identified two new SNPs in 36% of MCC patients, whereas no mutations were found in TP53 gene. Survivin was expressed in 78% of specimens. We could not correlate either mutations in PDGFR or expression of PDGFR, p53 and surviving either to the disease progression or to the MCPyV positivity. Conclusions In conclusion, our data indicate that the viral positivity when associated with high viral load, correlates with poor disease outcome. Frequent mutations in the PDGFRα gene and high survivin expression were found in MCC independent of the viral positivity. These data suggest that these three factors independently contribute to Merkel cell carcinoma development and that only the viral load can be used as indicator of disease progression in virus positive patients.
- Published
- 2015
69. Stimulus-dependent NETosis by neutrophils from a Papillon-Lefèvre Syndrome patient
- Author
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J. Steiger, I. Tantcheva-Poόr, Alexander Stephan, Sabine A. Eming, Marina Batinica, and Mario Fabri
- Subjects
0301 basic medicine ,business.industry ,Dermatology ,Papillon–Lefèvre syndrome ,Stimulus (physiology) ,medicine.disease ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Infectious Diseases ,030220 oncology & carcinogenesis ,Medicine ,business ,Neuroscience - Published
- 2016
70. Awake craniotomy - the anaesthesiologist´s view
- Author
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Inga Mladić Batinica
- Published
- 2017
71. Speech brain mapping by direct cortical stimulation during the awake craniotomy and possible increase in sympathetic activity: a case report
- Author
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Inga Mladić Batinica
- Published
- 2017
72. Proizvodnja i kakvoća Drniškog pršuta
- Author
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Batinica, Ivona
- Subjects
Drniški pršut, tehnološki proces, kakvoća, oznaka zemljopisnog podrijetla - Abstract
Pršut je jedan od najcjenjenijih i najkvalitetnijih mesnih proizvoda, a njegova proizvodnja vezana je uz priobalno područje. Tehnološki proces proizvodnje pršuta općenito se razlikuje od regije do regije, s obzirom na različitosti sirovine, tehnološkog procesa i uvjeta proizvodnje. Drniški pršut zaštićen je oznakom zemljopisnog podrijetla prema standardima Europske unije 2015. godine i predstavlja visoko kvalitetan mesni proizvod na svjetskoj razini. Drniški pršut se proizvodi na način da se svinjski but soli s krupnom morskom soli, preša, hladno dimi i suši, a proizvodi se tijekom razdoblja od minimalno dvanaest mjeseci. Karakterističnog je izgleda, bez zdjeličnih kosti i nožice, te dijela kože i masnog tkiva s unutrašnje strane buta, pravilno zaobljenog ruba. Odlikuje ga jednolična intenzivna rubin – crvena boja nareska, osim bjeline u području masnog tkiva, te intenzivan miris zrelog, blago dimljenog, sušenog svinjskog mesa. U trenutku stavljanja na tržište, Drniški pršut mora imati minimalnu masu od 6, 5 kg. Drniški pršut koji zadovoljava sve zahtjeve propisane u specifikaciji proizvoda, po završetku proizvodnje označava se na koži s lateralne strane vrućim žigom, a prije stavljanja u promet i zajedničkim znakom ovog proizvoda.
- Published
- 2017
73. Awake craniotomy - the anaesthesiologistu00b4s view
- Author
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Batinica, Inga Mladić, Rotim, K., and Sajko, T.
- Abstract
Awake craniotomy - the anaesthesiologist's viewInga Mladiu0107 Batinica1, K. Rotim2, T. Sajko2, M. Zmajeviu0107 Schonwald2, S. Salkiu010deviu010731Department of Anaesthesiology, Intensive Care and Pain Therapy, University Hospital Center u201cSisters of Mercyu201d, Zagreb, Croatia; 2Department of Neurosurgery, University Hospital Center u201cSisters of Mercyu201d, Zagreb, Croatia; 3Department of Psychology, Faculty of Humanities and Social Sciences, University of Zagreb, CroatiaE-mail: ingamblue@gmail.comBackground: Compared with surgery under general anaesthesia (GA), awake craniotomy (AC) is associated with advantageous outcomes. It is standard of care for tumors in eloquent brain areas. For anaesthesiologist it is a challenge because there is no standardized anaesthestic technique.Clinical case-series: During last three years, AC with monitored anaesthesia care (MAC) is successfully implemented in Croatia. We present single centre experience with thirteen patients (age 32-64 yrs; 7M, 6F; ASA II). After selection by multidisciplinary team (neurosurgeon, anaesthesiologist, neurologist, psychologist), patients were sedated and breathed spontaneously during the procedure. We used target controlled infusion pumps for fine titration of remifentanil and propofol, and for local infiltration at the site of pin insertion, skin incision and nerve blocks mixture of 0.5% bupivacaine and 2% lidocaine with adrenalin. Monitoring included: ECG, invasive and non-invasive BP, SPO2, RR, ETCO2, BIS and hourly urinary output. There were no surgical, neither anaesthesiological complications. Maximum alert and minimally stressed patients were optimal for awake brain mapping.Discussion: In anaesthetic management exists large variability and implementing AC is challenging for anaesthesiologist. Avoidance of GA prevents associated physiological disturbance, need for mechanical ventilation and utilization of anaesthetics that can play a role on antitumor immunity and tumor progression. It is difficult to differentiate the benefits related to anaesthetic care from those attributable to surgical technique. Using MAC, surgeonu2019s credit is an ability to increase the extent of resection and survival, while preserving neurological function. Anaesthesiologistu2019s credit is competence to avoid a complications of general endotracheal anaesthesia. Avoiding these factors may contribute to better outcome after AC. Our experience shows patientsu2019 satisfaction (evaluated by psychologist), with optimal intraoperative working conditions for neurosurgeon.Learning points: Crucial steps in establishment of an awake surgery is creation of a competent neuroanaesthesiologist, who are able to provide care for awake patients. Drugs fine titration, accurate respiratory function monitoring, good plan in dealing with possible respiratory complication and constant training in management of difficult airways are milestones of favourable outcome. In view of that, anaesthesiologist contribution to AC is essential.
- Published
- 2017
74. Biped walking and stairs climbing using reconfigurable adaptive motion primitives
- Author
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Aleksandar Batinica, Milutin Nikolic, Mirko Raković, José Santos-Victor, Branislav Borovac, and Srdan Savic
- Subjects
0209 industrial biotechnology ,Computer science ,business.industry ,Stair climbing ,02 engineering and technology ,Gait ,Preferred walking speed ,03 medical and health sciences ,020901 industrial engineering & automation ,0302 clinical medicine ,Stairs ,Climbing ,Robot ,Computer vision ,Artificial intelligence ,Set (psychology) ,business ,030217 neurology & neurosurgery ,Simulation ,Humanoid robot - Abstract
Humans can reliably walk in dynamic and unstructured environments, simultaneously handle stairs and obstacles, as well as the transition from one gait to another. Despite the outstanding progress in the last decades, today's robots are still far from attaining that level of performance. This paper presents a new way of walk and stair climbing realization with a smooth transition between two types of gait. The gaits are composed of Reconfigurable Adaptive Motion Primitives (RAMPs), which serves as building blocks for any walking pattern. A human locomotion experiment is conducted to better understand how human approaches and positions the foot in front of the stairs with respect to the overall walk characteristics. These findings are used to compare the results of a simulation experiment with humanoid robot performing same locomotion as the human subject. It is shown that the robot's path or gait shape can be modified by the set of overall gait parameters that can be changed at any time instance. The robot can approach stairs with a variable number of half-steps, switch smoothly to stair climbing, and back to walking on flat surface, and modify walking speed and direction on-line as humans can do.
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- 2016
75. Metal allergy as a late-onset complication of the Nuss procedure in a pediatric patient
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Navratil, Marta, primary, Batinica, Maja, additional, and Ivković-Jureković, Irena, additional
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- 2018
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76. 05 / Interventional neuroradiology- the specific challenges for anesthesiologist
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Mladić Batinica, Inga, primary, Videc, Lana, primary, and Kalousek, Vladimir, primary
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- 2018
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77. 08 / Comparison of normal saline and balanced crystalloid intravenous therapy during neurosurgery
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Kovac, Natasa, primary and Mladić Batinica, Inga, primary
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- 2018
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78. Generalization of task model using compliant movement primitives in a bimanual setting
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Batinica, Aleksandar, primary, Nemec, Bojan, additional, Santos-Victor, Jose, additional, Gams, Andrej, additional, and Rakovic, Mirko, additional
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- 2017
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79. Compliant movement primitives in a bimanual setting
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Batinica, Aleksandar, primary, Nemec, Bojan, additional, Ude, Ales, additional, Rakovic, Mirko, additional, and Gams, Andrej, additional
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- 2017
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80. Mortality after surgery in Europe: a 7 day cohort study
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Pearse, R, Moreno, R, Bauer, P, Pelosi, P, Metnitz, P, Spies, C, Vallet, B, Vincent, J, Hoeft, A, Rhodes, A, Fagnoul, D, van Obbergh, L, Al Subaie, N, Arif, F, Cashman, J, Cecconi, M, Edsell, M, Fossati, N, Hammond, S, Hamilton, M, Lonsdale, D, Moran, C, Siegmueller, C, Velzeboer, F, Wong, P, Awlakpui, E, Scheidemann, M, Wittmann, M, Damster, S, Golder, K, Hewson, R, Januszewska, M, Leva, B, Ramos, V, Hoste, E, Huyghens, L, Jacobs, R, Van Mossevelde, V, Opdenacker, G, Poelaert, J, Spapen, H, Leleu, K, Rijckaert, D, De Decker, K, Foubert, L, De Neve, N, Biston, P, Piagnerelli, M, Collin, V, den Blauwen, N, Clauwaert, C, De Crop, L, Verbeke, A, Derumeaux, P, Gardin, C, Kindt, S, Louage, S, Verhamme, B, Druwé, P, Lahaye, I, Rosseel, F, Rutsaert, R, Vanlinthout, L, De Kock, M, Forget, P, Georges, P, Grosu, I, Kahn, D, Lois, F, Momeni, M, Pospiech, A, Yemnga, B, Jadoul, J, Malbrain, M, Bosinceanu, D, Collard, E, Jorens, P, Reyntiens, D, Smitz, C, Vercauteren, M, Goranović, T, Mazul Sunko, B, Toplice, K, Oremuš, K, Bešlić, G, Duzel, V, Hauptman, A, Peremin, S, Šribar, A, Župčić, M, Brod, S, Mirković, I, Šarić Bauer, Z, Belavić, M, Blažanin, B, Katušin, M, Brozović Krijan, A, Mišković, P, Šimić Korać, N, Topić, J, Žilić, A, Žuni, J, Acan, I, Adanić, M, Ivanov, N, Pavičić Šarić, J, Tomulić, K, Visković, N, Bošnjak, S, Haršanji Drenjančevic, I, Kristek, G, Kvolik, S, Markić, S, Stojanovic Rakipovic, A, Katarina Tot, O, Venzera Azenic, D, Kalagac Fabris, L, Bačak Kocman, I, Balenović, I, Bandić, D, Judith Deutsch, P, Divjak, L, Filipović, I, Gužvinec, Z, Krznarić, Z, Lončarić, Y, Magaš, J, Mitrović, M, Okić, M, Pavlek, M, Ramov, E, Rezek, K, Sekulić, A, Tomasevic, B, Mirić, M, Tomašević, A, Tomić Mahečić, T, Vrbanović, V, Bobinac, M, Božić, A, Debelic, D, Frkovic, V, Batinica, I, Baranović, S, Gavranović, Ž, Kikec, M, Maldini, B, Marić, S, Agnić, I, Delić, N, Dropulić, N, Kljaković Gašpić, T, Ilić, D, Ivančev, B, Karanović, N, Kuščević, D, Marović, Z, Milić, M, Nevešćanin, A, Petković, T, Smoje, M, Brozović, G, Jelisavac, M, Matolić, M, Oberhofer, D, Marija Pavičić, A, Šakić, K, Delija Bozovic, M, Kotorac Krecek, Z, Krobot, R, Andabaka, T, Bratanić, M, Dzepina, O, Kraljev, M, Šeric, J, Šimurina, T, Grujić, R, Nacevski Bulaja, B, Barižon, M, Danira, V, Dražen, B, Dušanka, K, Bašić Halužan, M, Joško, Ž, Katica, R, Labor, M, Grgurević Marinković, T, Mihovilčević, D, Marija, B, Srečko, M, Vranković, S, Kyprianou, T, Neophytou, K, Cerny, V, Cvachovec, K, Belikova, B, Drab, M, Hudacek, K, Krikava, I, Stourac, P, Zadrazilova, K, Bicek, V, Brabcová, M, Klozová, R, Vajter, J, Vymazal, T, Toft, P, Blichfeldt, L, Dilling Hansen, B, Moller, K, Sylvest Nielsen, J, Frederiksen, J, Dohn Andersen, J, Peter Kühne, J, Leivdal, S, Stendell, L, Simonsen, M, Konrad Zoltowski, M, Salman Ali, Z, Freundlich, M, Pilypaite, J, Groes Clausen, N, Thorup, L, Hansen, F, Bestle, M, Steen Hansen, C, Afshari, A, Bastholm Bille, A, Lefort, M, Secher, E, Liboriussen, L, Herodes, V, Härma, E, Marvet, K, Pool, K, Kallas, P, Mägi, T, Sütt, J, Vijar, K, Visk, E, Vinnal, M, Ellermaa, J, Liibusk, L, Tikkerberi, A, Falk, I, Mällo, E, Talving, J, Pettilä, V, Hovilehto, S, Kirsi, A, Mustola, S, Tiainen, P, Toivonen, J, Dabnell, S, Kaminski, T, Sysimetsa, A, Kaukonen, M, Silvasti, P, Vainio, K, Lund, V, Sjövall, S, Saarinen, K, Viitanen, M, Ahonen, T, Alaspää, A, Zittling, R, Saarinen, A, Moisander, A, Wagner, B, Laru Sompa, R, Elomaa, E, Lavonen, L, Nevantaus, J, Geier, K, Kavasmaa, T, Koorits, U, Kubjas, M, Lauritsalo, S, Ottelin, L, Palve, M, Pynnönen, J, Rääbis, I, Saarelainen, M, Heikkilä, T, Kontula, T, Lehtimäki, M, Liimatainen, J, Moilanen Oikarinen, M, Pakarinen, M, Palanne, R, Seppänen, H, Pulkkinen, A, Vääräniemi, H, Koskenkari, J, Sälkiö, S, Vakkala, M, Koskue, T, Loisa, P, Laitio, R, Hautamäki, R, Koivisto, S, Futier, E, Lefrant, J, Leon, A, Bonnet, F, Marret, E, Spielvogel, C, Papageorgiou, C, Szymkiewicz, O, Tounou Akue, F, Aubrun, F, Bonnet, A, Gazon, M, Guiraud, M, Laurent, V, Tachon, G, Demars, N, Dumenil, A, Mercier, F, Landais, A, Mentec, H, Bazin, M, Gonnu, S, Petit, A, Albaladejo, P, Almeras, L, Bataillard, A, Rossi Blancher, M, Yves Lefrant, J, Barthel, F, Hallel, D, Sbai, H, Khalifeh, P, Lidzborski, L, Jully, M, Platon, E, Pottecher, J, Baumgarten, R, Schultz, C, Elmiloudi, F, Lefebvre, J, Waton, K, Sprunck, A, Steib, A, Thibaud, A, Thuet, V, Kieffer, V, Dubois Vallaud, D, Jacob, L, Becanne, X, Cherfaoui, S, Gauzit, R, Godier, A, Lakhdari, M, Samma, C, Bigeon, J, Burtin, P, Halchini, C, Lacroix, M, Pinna, F, Barbes, A, Just, B, Mateu, P, Benayoun, L, Berger, P, Granier, N, Francois Perrigault, P, Libert, N, De Rudnicki, S, Merat, S, Bourdet, B, Ferré, F, Minville, V, Piriou, V, Rague, P, Wallet, F, Lebuffe, G, Desbordes, J, Robin, E, Ichai, C, Orban, J, Marx, G, Sander, M, Gottschalk, A, Piontek, A, Unterberg, M, Hilpert, J, Kees, M, Triltsch, A, Wiegand Löhnert, C, Glöckner, C, Hohn, A, Rose, E, Schröder, S, Wiese, O, Ramminger, A, Dresden, C, de Abreu, M, Heller, A, Marx, C, Neidel, J, Goldmann, A, von Heymann, C, Laetsch, B, Maahs, E, Scholz, L, Frenzel, D, Massarat, K, Lenhart, F, Reichle, F, Rudlof, K, Borchers, F, Buettner, C, Schmutzler, M, Burgard, G, Lucht, A, Wagner, J, Pilge, S, Schneider, G, Untergehrer, G, Bis, B, Krassler, J, Dittmann, J, Haberkorn, J, Eberitsch, J, Eberitsch, K, Nippraschk, T, Wepler, U, Engelen, W, Nau, C, Scholler, A, Schüttler, J, Wintzheimer, S, Bloos, F, Braune, A, Fergen, D, Ludewig, K, Paxian, M, Reinhart, K, Graf, N, Schwarzkopf, K, Berger, K, Habicher, M, Kasperiunaite, R, Savelsberg, S, Krep, H, Reindl, M, Weber, M, Bauer, W, Bingold, F, Christ, S, Friederich, P, Kaviani, R, Auer, P, Bonnländer, G, Drescher, J, Braun, R, Eichenauer, T, Kerner, J, Bierbaum, K, Brünner, H, Grond, S, Perez Platz, U, Andresen, B, Linstedt, U, Stegmann, N, Erkens, U, Kopcke, J, Meyer, A, Brestrich, H, Ernst, S, Merkel, S, Krieger, L, Luers, F, Weyland, A, Noeldge Schomburg, G, Menckie, T, 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Crooks, N, Gao Smith, F, Melody, T, Snaith, C, Patel, J, Parekh, D, Yeung, J, Loughnan, B, Moosajee, V, Rope, T, Edger, L, Dawson, J, Hadfield, D, Hopkins, P, Mcdonald, L, Willars, C, Campbell, G, Craig, J, Ladipo, K, Lockwood, G, Moreno, J, Ballington, R, Hamandishe, S, Rogerson, D, Cowman, S, Hayden, P, Pinto, N, Sandhar, T, Arawwawala, D, Brotherston, L, Mitchell Inwang, C, Walsh, H, Alagarsamy, F, Goon, S, Karcheva, S, Krepska, A, Mckinney, B, Patil, V, Batchelor, N, Day, C, Finch, L, Gibson, C, Grayling, M, Hubble, S, Key, W, Knight, T, Loosley, A, Margetts, P, Stewart, H, Bewley, J, Hurley, K, Murphy, R, Philpott, C, Pollock, K, Sweet, K, Thomas, M, Tucker, K, Windsor, D, Conway, D, Gold, S, Quraishi, T, Cupitt, J, Baddeley, S, Brown, J, Foo, I, Mantle, D, Carvalho, P, Huddart, S, Kirk Bayley, J, Smith, R, Milligan, L, Poulose, S, Sarkar, S, Nolan, J, Pedley, E, Padkin, A, Pesian, S, Rajamanickam, S, Ramkumar, K, Crayford, A, Turner, A, Bottrill, F, Webb, S, Jhanji, S, Maccallum, N, Wessels, K, Wigmore, T, Meikle, A, Wilson, S, White, S, Bonnett, A, Rushton, A, Williams, C, Zuzan, O, Hall, A, Montgomery, J, Piggot, A, Read, R, Stocker, M, Tamm, T, Agarwal, B, Ward, S, Brown, L, Joy, M, Venkatesh, S, Hughes, T, Zsisku, L, Roy, A, Hooper, V, Mouland, J, Nightingale, J, Rose, S, Chiam, P, Chohan, H, Dickson, C, Gibb, S, Higham, C, Harvey, C, Janarthanan, C, Jones, L, Kapoor, A, Moll, M, Roberts, L, Saunders, D, Arnold, G, Gibbs, C, Jhurgursing, M, Pierro, D, Pritchard, F, Doyle, P, Templeton, M, Wilson, R, Zantua, K, Collyer, T, Featherstone, J, Worton, R, Bruce, J, Mcguigan, K, Price, G, Moreton, S, Pulletz, M, Anderson, H, Baxter, I, Beckingsale, A, Callaghan, M, Datta, A, Gollogly, J, Izod, C, Lobaz, S, Macfie, C, Patel, M, Payne, H, Singh, R, Timms, G, Mcleod, S, O'Brian, P, Horner, E, Joshi, V, Stuart Smith, K, Seale, T, Bolger, C, Collins, H, Ekins, E, Hawkins, L, Jonas, M, Linford, K, Wadams, B, Beach, M, Vizcaychipi, M, Jewsbury, W, Davies, S, Balaji, P, Kangaraj, M, Pissay, N, Smith, N, Gopalakrishnan, S, Mackinnon, J, Strandvik, G, Francis, R, Jennings, A, Keating, M, Kumar, S, Leese, S, Magee, C, Pilsbury, J, Ralph, J, Riddington, D, Sachdeva, R, Snelson, C, Vasanth, S, Wilde, J, Lavender, B, Lyons, R, Watters, M, Adams, T, Dyer, S, Tindall, L, Claxton, A, Netke, M, Akouds, E, Bates, D, Gallagher, H, Hatton, J, Holroyd, W, Mitra, A, Nurse, T, Reed, D, Desikan, S, Barber, R, Childs, S, O'Carroll Kuehn, B, Wyldbore, M, Al Abdaly, A, Amatya, S, Bhaskaran, S, Chandan, G, Chaudhry, S, Chikungwa, M, Earnshaw, G, Grewal, M, Haque, S, Hawkins, J, Javaid, A, Jackson, C, Kamel, M, Marla, R, Mculloch, D, Parker, T, Salib, Y, Saravanmuthu, R, Secker, C, Sockalingam, S, Taylor, A, Austine, P, Kanade, V, Paal, D, Sam Mok, M, Burtenshaw, A, Davis, L, Ellahee, P, Freeman, D, Pierson, R, Wollaston, J, Karmarkar, A, Ball, C, Calton, E, Maxwell, L, Walker, R, Bland, M, Bullock, L, Harrison Briggs, D, Hodge, P, Krige, A, Dempsey, G, Hammell, C, Loveridge, R, Parker, R, Snell, J, Wright, C, Baker, A, Barr, K, Belcher, A, Bonnington, S, Bougeard, A, Fitzgerald, E, Ford, R, Gillard, C, Griffiths, L, Greenberg, L, Huber, J, Mathieu, S, Richardson, N, Tompsett, L, White, N, Patel, S, Corner, V, Thomas, R, Trodd, D, Wilson, J, Copley, E, Flutter, L, Hulme, J, Susarla, J, Thwaites, A, Jayasundera, S, Mcafee, S, Chantler, J, Mckechnie, S, Neely, J, Mouton, R, Scarth, E, Soar, J, Buss, J, Currie, V, Sange, M, Kuttler, A, Power, F, Alexander, D, Dunne, K, Shinner, G, Black, E, Haldane, G, Kerr, J, Saran, T, Ward, G, Jefferies, F, Alexander, P, Royle, A, Nahla, F, Bowles, T, Gregory, M, Ahern, R, Cartlidge, D, Craker, L, Thompson, C, Bidd, H, Giles, J, Manser, A, Parry, G, Chan, P, Das, D, Fahmy, N, Higgins, D, Khader, A, Stone, A, Leonardi, S, Rose, O, Bright, E, Ercole, A, Amir Rafi, M, Ramasamy, R, Sheshgiri, B, Merrill, C, Page, V, Walker, E, Harris, S, Hughes, S, Morrison, A, Razouk, K, Ayman, M, Jakeman, A, Mowatt, C, Paananen, S, Translational Physiology, Other departments, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity, Anesthesiology, APH - Amsterdam Public Health, Pearse Rupert, Moreno Rui P., Bauer Peter, Pelosi Paolo, Metnitz Philipp, Spies Claudia, Vallet Benoit, Vincent Jean-Loui, Hoeft Andrea, Rhodes Andrew, Fagnoul David, van Obbergh Luc, Al-Subaie Nawaf, Arif Fuhazia, Cashman Jeremy, Cecconi Maurizio, Edsell Mark, Fossati Nicoletta, Hammond Sarah Jane, Hamilton Mark, Lonsdale Dagan, Moran Carl, Siegmueller Claa, Velzeboer Freya, Wong Patrick, Awlakpui Eli, Scheidemann Mona, Wittmann Maria, Damster Sandrine, Golder Kim, Hewson Russell, Januszewska Marta, Leva Brigitte, Ramos Vasco, Hoste Eric, Huyghens Luc, Jacobs Rita, Van Mossevelde Veerle, Opdenacker Godelieve, Poelaert Jan, Spapen Herbert, Leleu Kri, Rijckaert Dirk, De Decker Koen, Foubert Luc, De Neve Nikolaa, Biston Patrick, Piagnerelli Michael, Collin Vincent, den Blauwen Nadia, Clauwaert Charlotte, De Crop Luc, Verbeke An, Derumeaux Pieter, Gardin Christophe, Kindt Sebastiaan, Louage Sofie, Verhamme Bruno, Druwé Patrick, Lahaye Ingrid, Rosseel Franci, Rutsaert Robert, Vanlinthout Luc, De Kock Marc, Forget Patrice, Georges Pascal, Grosu Irina, Kahn David, Lois Fernande, Momeni Mona, Pospiech Audrey, Yemnga Bernadette, Jadoul Jean-Luc, Malbrain Manu, Bosinceanu Dana, Collard Edith, Jorens Philippe, Reyntiens Dirk, Smitz Carine, Vercauteren Marcel, Goranović Tatjana, Mazul-Sunko Branka, Toplice Krapinske, Oremuš Krešimir, Bešlić Gabrijela, Duzel Viktor, Hauptman Ada, Peremin Sanja, Šribar Andrej, Župčić Miroslav, Brod Slavonski, Mirković Ivan, Šarić Bauer Zlata, Belavić Matija, Blažanin Božidar, Katušin Mirjana Lončarić, Brozović Krijan Antonija, Mišković Petar, Šimić-Korać Nataša, Topić Jasna, Žilić Antonio, Žuni Josip, Acan Ivana, Adanić Mirta, Ivanov Nikola, Pavičić Šarić Jadranka, Tomulić Katarina, Visković Nataša, Bošnjak Silvana, Haršanji Drenjančevic Ivana, Kristek Gordana, Kvolik Slavica, Markić Stela, Stojanovic Rakipovic Andreja, Katarina Tot Ozana, Venzera-Azenic Darija, Kalagac Fabris Lada, Bačak-Kocman Iva, Balenović Igor, Bandić Daniela, Judith Deutsch Patricia Adrianne, Divjak Loredana, Filipović Ina Grčić, Gužvinec Zvonka, Krznarić Zrinka, Lončarić Yvonne, Magaš Jelena Vadlja, Mitrović Marek, Okić Marija, Pavlek Mario, Ramov Elza, Rezek Karolina, Sekulić Ante, Tomasevic Bori, Mirić Mirjana, Tomašević Anita, Tomić Mahečić Tina, Vrbanović Vilena, Bobinac Mirna, Božić Alfred, Debelic Danijela, Frkovic Vedran, Batinica Inga Mladić, Baranović Senka, Gavranović Željka, Kikec Mirna, Maldini Branka, Marić Stela, Agnić Ivan, Delić Nikola, Dropulić Nataša, Kljaković Gašpić Toni, Ilić Darko, Ivančev Božena, Karanović Nenad, Kuščević Dorjan, Marović Zlatko, Milić Matija, Nevešćanin Ana, Petković Tatjana, Smoje Mario, Brozović Gordana, Jelisavac Milana, Matolić Martina, Oberhofer Dagmar, Marija Pavičić Ana, Šakić Kata, Delija Bozovic Margarita, Kotorac Krecek Zvjezdana, Krobot Renata, Andabaka Tatjana, Bratanić Mislav, Dzepina Orjana, Kraljev Martina, Šeric Julija, Šimurina Tatjana, Grujić Rosa, Nacevski-Bulaja Biljana, Barižon Mirna, Danira Vrančić, Dražen Bulaja, Dušanka Kimer, Bašić Halužan Marijana, Joško Žaja, Katica Roca, Labor Magda, Grgurević Marinković Tea, Mihovilčević Danči, Marija Bego, Srečko Marinković, Vranković Srdan, Kyprianou Theodoro, Neophytou Kyriako, Cerny Vladimir, Cvachovec Karel, Belikova Barbora, Drab Michal, Hudacek Kamil, Krikava Ivo, Stourac Petr, Zadrazilova Katarina, Bicek Vladimír, Brabcová Milena, Klozová Radka, Vajter Jaromír, Vymazal Tomáš, Toft Palle, Blichfeldt Louise, Dilling Hansen Bo, Moller Kirsten, Sylvest Nielsen Jeppe, Frederiksen Joachim, Dohn Andersen Johnny, Peter Kühne Jan, Leivdal Siv, Stendell Line, Simonsen Martin, Konrad Zoltowski Marcin, Salman Ali Zahida, Freundlich Morten, Pilypaite Jurgita, Groes Clausen Nicola, Thorup Line, Hansen Frank, Bestle Morten, Steen Hansen Christian, Afshari Arash, Bastholm Bille Ander, Lefort Michele, Secher Erik L., Liboriussen Lisbeth, Herodes Veiko, Härma Eve, Marvet Kadri, Pool Kristiina, Kallas Pille, Mägi Triinu-Kreete, Sütt Jaan, Vijar Kerli, Visk Evelin, Vinnal Mare, Ellermaa Jaanu, Liibusk Liia, Tikkerberi Artur, Falk Ilme, Mällo Esta, Talving Jaak, Pettilä Ville, Hovilehto Seppo, Kirsi Anne, Mustola Seppo, Tiainen Pekka, Toivonen Juhani, Dabnell Sandra, Kaminski Tadeusz, Sysimetsa Anu, Kaukonen Maija, Silvasti Päivi, Vainio Kaisa, Lund Vesa, Sjövall Sari, Saarinen Kari, Viitanen Matti, Ahonen Tommi, Alaspää Ari, Zittling Ritva, Saarinen Aarne, Moisander Annette, Wagner Bodo, Laru-Sompa Raili, Elomaa Esa, Lavonen Leena, Nevantaus Juha, Geier Klau, Kavasmaa Tomi, Koorits Ursula, Kubjas Mare, Lauritsalo Seppo, Ottelin Lauri, Palve Markki, Pynnönen Jari, Rääbis Inga, Saarelainen Minna, Heikkilä Tapani, Kontula Timo, Lehtimäki Markku, Liimatainen Jari, Moilanen-Oikarinen Mari, Pakarinen Marika, Palanne Riku, Seppänen Hanna, Pulkkinen Anni, Vääräniemi Heikki, Koskenkari Juha, Sälkiö Sinikka, Vakkala Merja, Koskue Talvikki, Loisa Pekka, Laitio Ruut, Hautamäki Raku, Koivisto Simo-Pekka, Futier Emmanuel, Lefrant Jean-Yve, Leon Alain, Bonnet Franci, Marret Emmanuel, Spielvogel Catherine, Papageorgiou Chryssa, Szymkiewicz Olga, Tounou-Akue Felix, Aubrun Frederic, Bonnet Aurélie, Gazon Mathieu, Guiraud Michel, Laurent Virginie, Tachon Guillaume, Demars Nadège, Dumenil Anne-Sylvie, Mercier Frederic, Landais Alain, Mentec Herve, Bazin Marie, Gonnu Sophie, Petit Antoine, Albaladejo Pierre, Almeras Luc, Bataillard Amélie, Rossi-Blancher Marine, Yves Lefrant Jean, Barthel Florian, Hallel Dan, Sbai Hicham, Khalifeh Pamela, Lidzborski Lionel, Jully Marion, Platon Ecaterina, Pottecher Julien, Baumgarten Romain, Schultz Christel, Elmiloudi Fayçal, Lefebvre Julie, Waton Karen, Sprunck Adrien, Steib Annick, Thibaud Adrien, Thuet Vincent, Kieffer Vianney, Dubois-Vallaud Delphine, Jacob Laurent, Becanne Xavier, Cherfaoui Salim, Gauzit Remy, Godier Anne, Lakhdari Mourad, Samma Charle, Bigeon Jean-Yve, Burtin Philippe, Halchini Constantin, Lacroix Magali, Pinna Frederic, Barbes Aurélie, Just Bernard, Mateu Philippe, Benayoun Laurent, Berger Philippe, Granier Nathalie, Francois Perrigault Pierre, Libert Nicola, De Rudnicki Stephan, Merat Stéphane, Bourdet Benoit, Ferré Fabrice, Minville Vincent, Piriou Vincent, Rague Philippe, Wallet Florent, Lebuffe Gille, Desbordes Jacque, Robin Emmanuel, Ichai Carole, Orban Jean-Christophe, Marx Gernot, Sander Michael, Gottschalk André, Piontek André, Unterberg Matthia, Hilpert Justu, Kees Martin, Triltsch Andrea, Wiegand-Löhnert Carola, Glöckner Christiane, Hohn Andrea, Rose Elmar, Schröder Stefan, Wiese Oliver, Ramminger Axel, Dresden Caru, de Abreu Marcelo Gama, Heller Axel, Marx Christine, Neidel Julia, Goldmann Anton, von Heymann Christian, Laetsch Beatrix, Maahs Esther, Scholz Lar, Frenzel Dirk, Massarat Kyro, Lenhart Franz-Peter, Reichle Florian, Rudlof Kristina, Borchers Friedrich, Buettner Christoph, Schmutzler Martin, Burgard Gerald, Lucht Alexander, Wagner Jan, Pilge Stefanie, Schneider Gerhard, Untergehrer Gisela, Bis Beata, Krassler Jen, Dittmann Jan, Haberkorn Jörg, Eberitsch Jürgen, Eberitsch Karola, Nippraschk Thoma, Wepler Ulrich, Engelen Wolf-Christian, Nau Carla, Scholler Axel, Schüttler Jürgen, Wintzheimer Simone, Bloos Frank, Braune Anke, Fergen Daniela, Ludewig Katrin, Paxian Marku, Reinhart Konrad, Graf Nikolau, Schwarzkopf Konrad, Berger Katharina, Habicher Marit, Kasperiunaite Ruta, Savelsberg Sabine, Krep Henning, Reindl Michael, Weber Matthia, Bauer Wolfgang, Bingold Florian, Christ Saskia, Friederich Patrick, Kaviani Reza, Auer Patrick, Bonnländer Georg, Drescher Jürgen, Braun Roland, Eichenauer Tim, Kerner John, Bierbaum Kathrin, Brünner Horst, Grond Stefan, Perez-Platz Ursula, Andresen Bent, Linstedt Ulf, Stegmann Nil, Erkens Uwe, Kopcke Jen, Meyer Andrea, Brestrich Hartmut, Ernst Sandra, Merkel Stella, Krieger Lena, Luers Frank, Weyland Andrea, Noeldge-Schomburg Gabriele, Menckie Thoma, Wasmund Christina, Bredtmann Ralph-Dieter, Erler Ine, Raufhake Carsten, Haumann Christine, Möllemann Angela, Oehmichen Uwe, Sergejewa Olga, Lehning Brigitte, Czeslick Elke, Geyer Michaela, Malcharek Michael, Sablotzki Armin, Stier Marina, Feld Florian, Rossaint Rolf, Simon Verena, Armaganidis Apostolo, Koulenti Despoina, Kotanidou Anastasia, Nanas Serafim, Papastylianou Androula, Psevdi Aikaterini, Stathopoulos Anastasio, Voulas Asklepieion, Kanna Efthymia, Koutsikou Anastasia, Moustaka Alexandra, Chovas Achillea, Komnos Apostolo, Zafiridis Tilemacho, Franses Josef, Lavrentieva Athena, Koraki Eleni, Katsenos Chrysostomo, Flora Kasianidou Maria, Nasopoulou Pantelia, Spyropoulou Eleni, Gousia Chrysoula, Katsanoulas Constantine, Lathyris Dimitrio, Kyriazopoulos George, Sfyras Dimitrio, Tsirogianni Athanasia, Kostopanagiotou Georgia, Lignos Mihail, Matsota Paraskevi, Christopoulos Christo, Mouratidou Alexandra, Vrettou Efstratia, Boufidis Spyro, Moka Eleni, Arnaoutoglou Eleni, Koulouras Vasileio, Nakos George, Papathanakos Georgio, Anthopoulos Georgio, Choutas Georgio, Karapanos Dimitrio, Tzani Vaso, Gkiokas Georgio, Nastos Konstantino, Nikolakopoulos Fotio, Dragoumanis Christo, Nikitidis Niko, Pneumatikos Ioanni, Theodorou Vassiliki, Zacharouli Danai, Kandi Stella, Tasopoulos Konstantino, Arvaniti Kostoula, Matamis Dimitrio, Mplougoura Eva, Petropoulou Polixeni, Soumpasis Ioanni, Amaniti Ekaterini, Giannakou-Peftoulidou Maria, Gkeka Eleni, Soultati Ioanna, Kokinou Maria, Papatheodorou Lambrini, Stafylaraki Maria, Giasnetsova Tatiana, Gritsi-Gerogianni Nikoleta, Kydona Christina, Kiskira Olga, Koulentis Ioanni, Apsokardos Alexandro, Dimitropoulos Konstantino, Soldatou Ourania, Nathanail Christodoulo, Papazotos Alexio, Tsakas Pirro, Clouva-Molyvdas Phyllis-Maria, Kolotoura Athina, Sartzi Monika, Papanikolaou Spiro, Polakis Pavlo, Karatzas Styliano, Kyparissi Aikaterini, Papavasilopoulou Theonymfi, Koukoubani Triantafillia, Mastora Evangelia, Spyropoulou-Pagdatoglou Kyriaki, Nyktari Vasileia, Malliotakis Polychroni, Papaioannou Alexandra, Bekos Vasileio, Maragkou Elisavet, Spring Anna, Evagelatos Stavro, Ioakeimidou Aikaterini, Noulas Niko, Molnár Zsolt, Csüllög Emese, Elekes Eniko, Molnár Tamá, Katona Zsuzsana, Kremer Ildiko, Miko Angela, Csomos Ako, Galambos Zsuzsanna, Szucs Ako, Nyikos Gyorgy, Szekeres Gabor, Szabo Ervin, Kranitz Katalin, Simon Melinda, Szigeti Jano, Gaál Emánuel, Havas Attila, Ille Alexandru, Bráz Krisztina, Nagy Geza, Sigurdsson Gisli, Sigurbjörnsson Fridrik T., Sigurdsson Gisli H., Kárason Sigurbergur, Edda Sigurdardottir Elin, Blöndal Ásbjörn, Gunnarsson Björn, Westbrook Andrew, Broderick Alan, Hafeez Parvaiz, Hanumanthaiah Deepak, Brohan Janette, O'Chroinin Donal, Bailey Kevin, Ramamoorthy Karthik, Doyle Yvonne, Freir Noelle, O'Rourke Jame, Jonson Philip, Saeed Sabir, Hayes Ivan, Loughrey John, Frohlich Stephen, Mccauley Nuala, Ryan Donal, Fitzpatrick Gerry, Kevin Leo, Thomas Jubil, Warde Barry, Woolhead Alan, Duggan Michelle, Egan Cara, Crowley Seamu, Lebese Soloman, Bergin Anne, Page Rory, Collins Daniel, Mckenny Michael, Della Rocca Giorgio, Grasso Salvatore, Bresciani Anna, Carmino Livio, Ghelfi Silvia, Lorenzelli Laura, Teresa Novelli Maria, Pescarmona Chiara, Roasio Agostino, Gatta Alessandro, Nastasi Mauro, Sanseverino Manlio, Tinti Carla, Bianchin Andrea, Tormena Maria, Franco Antonio, Marini Federica, Di Mauro Piero, Rapido Francesca, Tommasino Concezione, Bellotti Ferdinando, Boninsegna Daniele, Castellani Gianluca, Sances Daniele, Spano Gianluca, Tredici Stefano, Vezzoli Dario, Fucecchio Igneo, Bacci Alessandro, Coppini Roberta, Dell'Unto Sandro, Mori Emanuele, Rosa Stanzani Maria, Tosi Monica, Collareta Michele, Forfori Francesco, Franchi Matteo, Mancino Giuseppe, Battistella Massimo, Baricocchi Elisa, Bona Francesco, Debernardi Felicino, Giacoletto Gianmarco, Iacobellis Antonio, Massucco Paolo, Moselli Nora, Muratore Andrea, Palomba Graziella, Sardo Elena, De Simone Michele, Suita Luisa, Zocca Edoardo, Bucci Barbara, Della Corte Francesco, Piciucco Tiziana, Viarengo Valeria, Bettelli Gabriella, Cantarini Eugenia, Giampieri Marina, Tanfani Alessandra, Recchia Eugenio, Bignami Elena, Bruno Giovanna, Costagliola Roberto, Gandolfi Azzurra, Greco Massimiliano, Lembo Rosalba, Monti Giacomo, Nicelli Elisa, Pasculli Nicola, Turi Stefano, Baroselli Antonio, Brazzoni Marcella, Buttazzoni Mattia, Buttera Stefania, Centonze Carlo, Serena Giovanni, Spagnesi Lorenzo, Toretti Ilaria, Vilardi Anna, Zearo Ester, Arpino Ine, Baraldi Sara, Guarnerio Chiara, Molene Vincenzo, Concetta Monea Maria, Vaccarisi Enrico, Vicari Luigi, Albante Alida, Aversano Marco, Loiacono Cinzia, Marandola Maurizio, Fusari Maurizio, Petrucci Nicola, Galla Amerigo, Mascia Antonio, Primieri Paolo, Di Noto Anna, Gratarola Angelo, Molin Alessandro, Spagnolo Luigi, Spena Claudio, Calligaro Plinio, Marchiotto Simonetta, Merlini Alberto, Pedrazzoli Eleonora, Perina Giulia, Visentin Renea, Fumagalli Roberto, Garbagnati Andrea, Manetti Bruna, Snaier Chiara, Somaini Marta, Farnia Antonio, Nani Roberto, Pierantonio Novello, De Michele Michele, Gazzanelli Sergio, Pugliese Francesco, Ruberto Franco, Bergamini Elena, Tassinati Tania, Capuzzo Maurizia, Cirillo Vera, Tufano Rosalba, Oggioni Roberto, Parrini Vieri, Brunori Emanuela, Capone Micaela, Carbone Luigi, Corradetti Francesco, Elisei Daniele, Fiorentino Stefano, Francesconi Maurizio, Gattari Diego, Gorgoglione Maria, Lacobone Emanuele, Minnucci Francesco, Montironi Claudio, Riccioni Gianrenato, Tappata Giuseppe, Zompanti Valeria, Verdenelli Paola, Cerutti Elisabetta, Ranieri Vito Marco, Golubovska Iveta, Grigorjevs Sergej, Rikmane Maija, Rozkalne Daina, Stepanovs Jevgenij, Suba Oleg, Kazune Sigita, Miscuk Aleksej, Nemme Jani, Oss Peteri, Sipylaite Jurate, Macas Andriu, Ragaisis Vytauta, Kontrimaviciute Egle, Tomkute Gabija, Boerma Christiaan, Fleur Kramer Irene, Poeze Martijn, Maria John, Pelzer Gerardu, Winsser Lex, Nijsten Maarten, Schoorl Michiel, Spanjersberg Rob, Buhre Wolfgang, Dieleman Stefan, van Klei Wilton, Bouw Martijn, Pickkers Peter, van der Marieke A., Schreiner Frodo, Zandvliet Ria, van den Berg Roy, De Wit Esther, Keijzer Christaan, Hollmann Marku, Preckel Benedikt, van Acker Gij, Dennesen Paul, Veld Ba, Kuijpers-Visser Agne, Inan T., Koopman-van Gemert A., Ponssen Huibert, Brouwer Tammo, Koopmans Matty, van Bommel Jasper, van Duijn Ditty, van der Hoven Ben, Ormskerk Patricia, Beck Oliver, Schiere Sjouke, Reidinga Auke, Venema Allart, Hoogendoorn Marga, Olthof Kee, Flaatten Han, Jammer Ib, Dokka Vegard, Arne Monsen Svein, Marius Ytrebo Lar, Noursadeghi Mostafa, Shahzad Ahmed, Dagfinn Boksasp Ola, Roiss Christoph, Frank Strietzel Han, Gina Anne, Berntsen Schie, Haugland Helge, Ove Vingsnes Svein, Axelsson Patric, Risom Olsen Thoma, Katre Sanjay, Aakeroey Kristin, Mikstacki Adam, Tamowicz Barbara, Boziłow Dominika, Goch Robert, Grabowski Piotr, Kupisiak Jacek, Małłek Małgorzata, Szyca Robert, Kostyrka Włodzimierz, Choma Robert, Jankowski Grzegorz, Kościelniak Władysław, Pietraszek Paweł, Szarowar Bartosz, Matos Ricardo, França Carlo, Pais Lacerda António, Ormonde Lucindo, Rosa Rosário, Pereira Inê, Vitor Paula, Completo Bento Henrique, Raquel Lopes Maria, Carvalho Marque, Faria Manuela, Cláudia de Sousa Ana, de Freitas Pereira, Almeida Eduardo, Mealha Rui, Vicente Rachel, Monte Raquel, Rua Fernando, Barros Nelson, Esteves Francisco, Gouveia Pinheiro Célia Maria, Real Vila, Miguel Oliveira Vítor, Fátima Oliveira Maria, Martins Isabel, Pedro Saraiva José, Pedro Assunção José, Bártolo Anabela, Carvalho Anabela, Correia Carlo, Martins Salomé, Milheiro Ruth, Diaz Alejandro, Imelda Gonçalves Maria, Ribeiro Rosa, Estilita Joana, Glória Carlo, de Almeida José, Barros Filipa, Ramos Armindo, Camara Margarida, Richard Maul Edward, Nobrega Julio, Langner Anuscka, Faria Maia Dionísio, Afonso Ofélia, Faria Filomena, Serra Sofia, Manuela Botelho Maria, Ferreira Pedro, Mourão Luí, Vintém Oliveira Ana, Resende Margarida, Aleman Miguel, Fonseca Jorge, Isidoro Marta, de Meneses Helena, Pêgas António, Pereira José, Pereira Lui, Ramos Bárbara, Matos Francisco, Gonçalves Castro Maria de Lurde, Martins Ana, Ramos Cristina, de Sousa Manuel, Bento Luí, Botas Conceição, Lopes Vitor, Mendes Rosa, Grigoras Ioana, Blaj Mihaela, Damian Mihaela, Lupusoru Andreea, Ristescu Irina, Codreanu Monica, Diaconescu Ciresica, Nistor Alina, Stanescu Stelian Dorin, Streanga Livia, Berneanu Maria, Bordeianu Cristina, Florenta Calarasu, Iacob Alina, Nicoleta Lupu Mary, Mocanu Iulian, Moraru Coca, Meran Carleta, Nicolae Bacalbasa, Sandu Madalina, Turcanu Roxana, Epure Florina, Grigore Monica, Hotaranu Cristina, Popescu Nicoleta, Baban Oleg, Baciu Manuela, Ciobanu Aurica, Ioan Denciu Catalin, Gurau Vitalie, Maftei Ion, Moldovan Ion, Ungureanu Liviu, Bogdan Prodan, Corneci Dan, Dinu Melania, Madalina Dutu, Rely Manolescu, Silvius Negoita, Tomescu Dana, Gabriela Droc, Adrian Dinescu Stelian, Calin Mitre, Ionescu Daniela, Margarit Simona, Vasian Horatiu, Albu Corina, Balasa Carmen, Cadrigati Alina, Dragulescu Dorian, Gavra Loredana, Hentia Ciprian, Macarie Claudiu, Manescu Mihaela, Nediglea Ioan, Ocica Dana, Ovidiu Bedreag, Papurica Mariu, Plavat Cosmin, Popa Claudia, Ramneantu Mihaela, Sandesc Dorel, Sandici Zoran, Sarandan Mihaela, Belciu Ioana, Tincu Eugen, Ursu Irina, Aignatoaie Mariana, Huzuneanu Mariana, Cocu Simona, Hagau Natalia, Ciubotaru Roxana, Copotoiu Sanda-Maria, Copotoiu Ruxandra, Ioana Ghitescu, Kovacs Judit, Leonard Azamfirei, Szederjesi Iano, Genoveva Vanvu, Mosnegutu Simona, Surbatovic Maja, Djordjevic Dragan, Djordjevic Biljana, Grujic Krasimirka, Jovanovic Dusko, Krstic-Lecic Ivana, Obradovic Jovana, Zeba Snjezana, Jevdjic Jasna, Miletic Milo, Zunic Filip, Bulasevic Aleksandra, Brko Radoslava, Gazibegovic Narcisa, Kendrisic Mirjana, Vojinovic Radisa, Firment Jozef, Zahorec Roman, Capková Judita, Grochova Monika, Trenkler Stefan, Griger Martin, Bakosova Erika, Kvasnica Martin, Saniova Beata, Sulaj Miroslav, Zacharovska Andrea, Simkova Alexandra, Číková Andrea, Gebhardtova Andrea, Hanuljaková Slávka, Koutun Juraj, Martonová Andrea, Žilinčárová Veronika, Galkova Katarína, Krbila Stefan, Sobona Viliam, Ocenasova Marieta, Novak-Jankovic Vesna, Stecher Adela, Stivan Feri, Grynyuk Andriy, Damjanovska Marija, Kostadinov Ivan, Knezevic Mile, Malivojevic Marko, Borovsak Zvonko, Kamenik Mirt, Mekiš Dušan, Osojnik Irena, Kosec Lučka, Ostojič Kapš Silva, Aleksic Dragoslav, Gerjevič Božena, Kalan Katja, Ursic Tomaz, Aldecoa Cesar, Montejo González Juan, Artigas Anna, Garcia Andre, Lisi Alberto, Perez Isabel, Perez Gisela, Poch Nuria, Vaquer Sergi, Balciscueta Goiatz, Barrasa Helena, Cabanes Sara, Maynar Javier, Poveda Yolanda, Quintano Rodero Amaia, Vallejo Ana, Duque Patrícia, Garcia-Bunger Beatriz, Adoracion Elvira Maria, María Lajara Ana, Palencia María, Ramos Rafael, Saez Fernandez Ana, Tirapu León Juan, Iza López Jaione, Yoldi Murillo Francisco, Turumbay Ramirez Eva, Unzué Rico Patricia, Patricia Marta, Vizcaíno Martín, Bernat Álvarez Maria José, Planas Real Kenneth, Mas Serra Arantxa, Aracil Norma, Menendez Bodega Begoña, Fernández García Raquel, Álvarez García Marivi, Gordon Borja de la Quintana, Gutiérrez Jodrá Alicia, De Santos López Angela, Llavador Ros Juan José, Ayala Soto Rocío, Sepúlveda Isabel, Pascual Díez Esperanza, Fernández Fernández Luisa, Soria Gulina Carlo, Pérez Arviza Laura, Fernandez Lorena Mouriz, Río Gómez Antía, Alonso Martínez Concepción, Rodríguez Rodríguez Ana Belén, Lopez Soto Carmen, Garcia Clara, Lorenzo Mario, Pinilla Elena, Rico Jesu, Ruperez Irene, Saiz Alonso Eduardo, Leira Fernando, Emilio Maseda David Pestaña, Royo Concepcion, Villagran Jose, Murillo Candi Giralt, Eduardo Esteva Garcia, Mansilla Folgado Raquel, Joan Fornaguera Nadal, Calonge Montse Pijoan, Sape Prat Anna, Sintes Dolore, Arteta Arteta Donaldo, García Delgado Horacio, Fajardo López-Cuervo Juan, López Mikel Celaya, Ramírez Alejandro, José Saldaña Francisco, Aliste Pilar, Hermira Anchuelo Ana, García Campos Ascensión, Catalán Mercede, García Gómez Mónica, Gonzalez Gonzalaez Olga, López López Eloísa, Real Navacerrada Isabel, de Quevedo Sara Arlanzón, Gonzalez Serrano Matilde, Silvestre Francisco Perez-Cerdá, Martinez Torrente Francisco, Arocas Blanca, Pastor Martinez Ernesto, Soro Marina, Maroto Fernando, Robledo Algarra Ruth, Silla Aleixandre Iné, Argente Gemma Rodriguez, Lleó Ana Broseta, Rubio Antonio Vela, Vicente Sánchez José Lui, Enríquez Valcárcel Irene, Balust Clara, Balust Jaume, Borrat Xavier, Jose Carretero Maria, Gracia Isabel, Matute Purificacion, Mercadal Jordi, Pujol Roger, Tena Beatriz, Ubre Marta, Dorda Albalad Dolore, Muñoz Alcaide Concepción, Caballero Jesu, Camps Cervantes Angel, de Nadal Clanchet Miriam, Montferrer Estruch Nuria, Ballvé Ferrer Mercè, Lacasta Fornells Albert, Terrer Galera Eduard, Garcia Martinez Irene, Manrique Muñoz Susana, Pelavski Andre, Tormos Perez Pilar, Gonzalez Posada Miguel Angel, de Prat Ivette Chocron, Rello Jordi, García Serrano Llum, Naya Sieiro José Manuel, Silva Lorena, Colomina Sole Maria Jose, Biarnes Suñé Alfon, Rochera Villach Isabel, Gómez Herreras José Ignacio, Poves Rodrigo, Martinez Rafael Beatriz, Martinez Almeida Icier, Fernandez Collates Angel, Jose Bartolomé Maria, Cimadevilla Bonifacio, González González Antonio Manuel, Rabanal Llevot Jose Manuel, de Terán Mira Juan Carlos Diaz, González Molina Begoña, Pardo Sara, López Sánchez Carlo, Williams Monica, Zaldibar Estibaliz, Muñoz Corsini Lourde, Rodríguez Fraile José Ramón, de la Lastra Maria, Kabiri Sacramento Monir, López Saña Francisco Javier, Trenado Ålvarez Josep, Cantón Bulnes Maria Luisa, Gándara Carrasco Violeta, Crespo Ma del Rocío Míguez, Narváez Cubillos Diana, Laza Laza Enrique, Pérez Ma del Pino Heredia, Arenzana Seisdedos Ángel, Fernández Torres Bartolomé, Santos Ampuero Marian, Chicot Llano Marta, Mata Esperanza, Munoz Manuel, Orts Mar, Planas Antonio, Ramasco Fernando, Roman Carlo, Varela Durán Marina, Fernandez Sabela del Río, Sanduende Otero Yolanda, Lopez Pineiro Susana, Barreiro Pardal Cristina, Fernández Alcantud Jesú, Ayuso Antolinos Mercede, Barrios Francisco, Collantes Casanova Ana, Ruiz Castro Manuel, Infantes Crespo Beatriz, Lancha Felipe Uzuri, Liceras Fuster Marta, Sanz García Máximo, Herrero Garrote Begoña, Moreno Gonzalez Ricardo, Montes Granero Maria José, de la Guía Carlos Lloreda, Chaves López Raquel, de Frutos López Santiago, Marco Martinez Jose Javier, Garcia Mostaza Angel, Jiménez Moreno Antonio, Riquelme Osado Irene, Bardina Pastor Ana, Peña Rosa, Rustarazo Pérez Mónica, Aliaño Piña María, Aranda Romero Carlo, Rodríguez Elena Rodríguez, Pedroviejo Sáez Vicente, Safatle Fernando, Hernández Salvan Javier, Galán Sampedro Mar, de la Torre Patricia Alfaro, Pérez Toro Jonatan, Lasa Unzúe Crsitina, José Vargas Maria, Garcia Bernal David, Echevarria Mercede, Ubeda Iglesias Alejandro, Loza Ana, Rodriguez Morillo Araceli, Diaz Serrano Pedro, Barrientos Sevilla Fernando Caba, Cacho Elena, Calderón Ricardo, Dufur Mercede, Marginet Carolina, Monedero Pablo, José Yepes Maria, Rellán Alvarez Luzdivina, Fernández Carballal Francisca, Pensado Castiñeiras Alberto, Dieguez García Paula, Ramos López Lorena, Rama Maceiras Pablo, Martínez Puente María Socorro, Rey Rilo Maria Teresa, Trujillo Alonso Ana Esther, Rodríguez Fernández Sonia, Omaña García Rafael, Pérez García Aníbal, Bello Puentes Rafael, Nunez Aguado Domingo, Lopez Carballo Carlo, Fernandez Fernandez Ricardo, Toledo Presedo Amadeo, de Rabago Ricardo Bermejo Diaz, Rodriguez Velasco Ana, Jiménez Capel Yolanda, Fernández Cortés Ana, Martínez García Esther, Martinez Gimeno Laura, Klamburg Jordi, Castillo Omedas Rosa, González Núñez Miriam, Llubià Maristany Clara, Moret Ruiz Enrique, Artigas Xavier, Castrillón Sebastian, Espinosa Nieve, Gomez-Caro Ana M., Illa Susana, India Inmaculada, Martín-Huerta Beatriz, Moral Victoria, Moreno Marisa, Iglesias Fernández Cristina, Fernández García Violeta, Picatto Hernández Pedro, Honrubia Checa Angel Alberto, Salvatierra Diaz David, Linero Noguera Manuel, Pujol Varela Ignacio, González Gallego Miguel, Martínez García Oscar, Ariño Irujo José Javier, González Perrino Carlo, Rey Picazo Julio, López Timoneda Francisco, Manzanero Arroyo María, Albalá Blanco Isabel, Martínez Borja Marco, Martín Burcio Sara, Martinez Castro Nilda, Puente Cerdeiriña Aránzazu, de la Torre Concostrina Marta, Viñas Cristina Medrano, Dorado Díaz Trinidad, Avellanosa Esteruelas Juan, Ingelmo Ingelmo Ildefonso, Duran Insuga Paco, Claros Llamas Elisabeth, Martín Lopez Jose Juan, Beltran Martín María, Elías Martín Elena, Ureta Mesa Eva, Loren Monterde Manuela, Alonso Montoiro Paloma, Gonzalez Móstoles Maria Luisa, Velasco Olarte Eva, Martínez Pérez Adolfo, Domínguez Perez Fernando, Serrano Romero Ana, Parise Rous Diego, Mané Ruiz Nuria, Palomo Ruiz Jose Angel, Ruigomez Saiz Alvaro, Terol Alvaro de la Vega, Candela Toha Angel, Alvarez Utrera Fernando, Alberdi Fermín, Elósegui Itxaso, García Javier, Marco Garde Pilar, Itziar Mintegui Escudero, García Sáez Iker, Salas Estibaliz, Zabarte Mercede, Diaz-Boladeras Rosa-Maria, Mora-Guevara Emilio, Ferreras Zamora Julia, Bonet Alfon, Salo Lidia, Salinas Unai, Zaballos Juan, Abella Alvarez Ana, Jimenez Garrido Carlo, Hita Roa Juan Ramón, Gordo Vidal Federico, Garcia-Egea Jorge, Zamora Elson Monica, Seron-Arbeloa Carlo, Mendiola Asensio Miguel Angel, Gastaldo Simeón Rosa, Muñoz Alameda Luis Enrique, Oeding Angulo Guillermo, Aranzubia Monserrat, Juan Arcas Jose, Arevalo Julian, Quesada Belvert Belén, Pérez Calvo César, Cremades Marta, Crespo Pascual, Cuarental Ana, Del Olmo Mercede, Turrión Fernández Pablo, Garcia Vega José Luis Franqueza García Isabel, Herrera Elena, Alcala Llorente Miguel Angel, Martin Rabes Cecilia, de Maeyer Ana Gamo, Pérez Marquez Manuel, López Mendoza Diego, Milicua Muñoz José María, Arias Martínez Natividad, Santos Oviedo Arnoldo, Benavent Garrigues Pau, Alonso Íñigo José, Tormo Ferrandiz Sergi, Sanchez-Morcillo Silvia, Lafuente Sánchez Matilde, Marqués Parra Asunción, Gomar Vidal Sonia, Montoiro Allué Raquel, Zalba Etayo Begoña, Bustamante Rodriguez Raquel, Martin Villen Lui, Molla Jimenez Cristina, de Zayas Ricardo Sala, Dolera Moreno Cristina, SanJose Pacheco Fernando, Anton Pascual Jose Lui, Tejera Gude Fernando, Manteiga Riestra Eva, Cota Delgado Francisco, de la Torre Prados Maria Victoria, Barrios Javier, Cervera-Montes Manuel, García-Sanz Mercede, García Vicente, Sanmiguel Guillermo, López Álvaro Julian, Bornay Barrachima Beatriz, Romero Bermejo Francisco Jose, Martinez Garcia Alberto Garcia Fernandez Pilar, Navarro Ramírez Carolina, Gómez Ramos Jorge, Angel Samaniego Lui, Belenguer-Muncharaz Alberto, Ferrándiz-Selles Amparo, Mateu-Campos Maria-Lidon, Domínguez David, Espinosa Elena, León Teresa, Ojeda Betancor Nazario, Garcia Cortes Javier, Díaz Díaz Juan José, Manzano Canalechevarria Ana, Fores Novales Beatriz, Garcia Peña Jose Manuel, Rodriguez Delgado Toma, Santamaria Roquerio Beatriz, Gomez Sainz Juan Jose, Tebar Soto Teresa, Chew Michelle, Seeman-Lodding Heléne, Dahm Peter, Odenstedt Hergès Helena, Lundborg Christoffer, Söndergaard Sören, Rylander Christian, Sari Ferenc, Oscarsson Tibblin Anna, Adolfsson Anne, Klarin Bengt, Schrey Susann, Merisson Edyta, Rydén Jörgen, Britt Divander Mona, Hedin Annika, Hedlund Daniel, Axelsson Lindkvist Mikael, Jawad Monir, Layous Lona, Wernerman Jan, Björne Håkan, Brattström Olof, Olheden Staffan, Oldner Ander, Sellden Eva, Walder Bernhard, Wickboldt Nadine, Rossi Ariane, Steiner Luziu, Djurdjevic Mirjana, Lussmann Roger, Geisen Martin, Hofer Christoph, Turina Matthia, Grocott Mike, Goldhill David, Everett Lynn, Harris Katy, Wright Maggie, Adams David, Alderson Lorraine, Baker Julie, Christie Iain, Ferguson Colin, Hill Matthew, Holmes Kate, Hutton Andrew, Minto Gary, Moor Paul, Porter Andrew, Struthers Richard, Akotia Niven, Belhaj Alaa, Chang Serene, Collantes Enrique, Eigener Katrin, Husband Michael, Khan Ahsun, Kong Ming-Li, Jane McAlees Eleanor, Macdonald Neil, Niebrzegowska Edyta, Parnell Wendy, Smith Amanda, Chhatwal Ally, Jhingan Smriti, Muswell Richard, Poon Yoyo, Singh Nidhita, Stephens Robert, Vasan Robin, Waife Nicola, Weda Tahmina, Clarke Adrian, Szakmany Tama, Fletcher Simon, Rosbergen Melissa, Blunt Mark, Prince Liz, Wong Kate, Kumar Ram, Stilwell Sarah, Couper Keith, Crooks Neil, Gao-Smith Fang, Melody Teresa, Snaith Catherine, Patel Jaimin, Parekh Dhruv, Yeung Joyce, Loughnan Bernadette, Moosajee Va, Rope Tamsin, Edger Lliam, Dawson Julie, Hadfield Daniel, Hopkins Phil, Mcdonald Lisa, Willars Chri, Campbell Gillian, Craig Jayne, Smith Andrew, Ladipo Karleen, Lockwood Geoff, Moreno Juan, Ballington Ruth, Hamandishe Sibongilele, Rogerson David, Cowman Sarah, Hayden Paul, Pinto Nuno, Sandhar Taj, Arawwawala Dilshan, Brotherston Lauren, Mitchell-Inwang Christine, Walsh Helena, Alagarsamy Famila, Goon Serena, Karcheva Sylvia, Krepska Amy, Mckinney Brian, Patil Vishal, Batchelor Nichola, Day Christopher, Finch Louise, Gibson Charlie, Grayling Matthew, Hubble Sheena, Key William, Knight Thoma, Loosley Alexander, Margetts Paul, Stewart Hannah, Bewley Jeremy, Hurley Katrina, Murphy Ruth, Philpott Catherine, Pollock Kathryn, Sweet Katie, Thomas Matthew, Tucker Katy, Windsor David, Conway Daniel, Gold Steve, Quraishi Tanviha, Cupitt Jason, Baddeley Sally, Brown John David, Foo Irwin, Mantle Damien, Carvalho Peter, Huddart Sam, Kirk-Bayley Justin, Smith Rebecca, Milligan Lisa, Poulose Sonia, Sarkar Som, Nolan Jerry, Pedley Emma, Padkin Andrew, Pesian Siamak, Rajamanickam Satish, Ramkumar Konnur, Thomas Jerry, Crayford Alison, Turner Angu, Bottrill Fiona, Webb Stephen, Jhanji Shaman, Maccallum Niall, Wessels Kate, Wigmore Tim, Meikle Alistair, Wilson Stephen, White Stuart, Bonnett Andrew, Rushton Andrew, Williams Colin, Zuzan Oliver, Hall Andrew, Montgomery Jane, Piggot Ailie, Read Richard, Stocker Mary, Tamm Tiina, Agarwal Banwari, Ward Stephen, Brown Lucy, Joy Manju, Venkatesh Suresh, Hughes Thoma, Zsisku Lajo, Roy Alistair, Hooper Victoria, Mouland Johanna, Nightingale Jeremy, Rose Steve, Chiam Patrick, Chohan Harnita, Dickson Chri, Gibb Sarah, Higham Charley, Harvey Caroline, Janarthanan Chandra, Jones Laura, Kapoor Avinash, Moll Mark, Roberts Louise, Saunders David, Arnold Glenn, Gibbs Claire, Jhurgursing Mhairi, Pierro Dena, Pritchard France, Doyle Patrick, Templeton Maie, Wilson Robert, Zantua Kim, Collyer Thoma, Featherstone Jame, Worton Rachael, Bruce Jean, Mcguigan Kate, Price Grant, Moreton Sarah, Pulletz Mark, Anderson Helen, Baxter Ian, Beckingsale Alex, Callaghan Mark, Datta Ansu, Dawson Jo, Gollogly Jackit, Izod Chri, Lobaz Steve, Macfie Caroline, Patel Manju, Payne Heather, Singh Raj, Timms Gemma, Mcleod Shaun, O'Brian Peter, Horner Elspeth, Joshi Vivekananda, Stuart-Smith Karen, Seale Tania, Bolger Clare, Collins Hannah, Ekins Emma, Hawkins Lesley, Jonas Max, Linford Karen, Wadams Beverley, Beach Madeleine, Vizcaychipi Marcela, Jewsbury William, Davies Simon, Balaji Packianathaswamy, Kangaraj Muthuraj, Pissay Nagesh, Smith Neil, Gopalakrishnan Senthilkumar, Mackinnon John, Strandvik Gustav, Francis Ruth, Jennings Adrian, Keating Matthew, Kumar Sajith, Leese Sarah, Magee Cliona, Pilsbury Jane, Ralph Jame, Riddington David, Sachdeva Rajneesh, Snelson Catherine, Vasanth Suresh, Wilde Judith, Lavender Beth, Lyons Rachel, Watters Malcolm, Adams Tim, Dyer Simon, Tindall Lucy, Claxton Andrew, Netke Meenu, Akouds Esam, Bates Debrah, Gallagher Heather, Hatton Jonathan, Holroyd William, Mitra Atideb, Nurse Trudy, Reed Deborah, Desikan Somi, Barber Russell, Childs Sophie, O'Carroll-Kuehn Britta, Wyldbore Mark, Al-Abdaly Ayad, Amatya Suman, Bhaskaran Sherly, Chandan Garud, Chaudhry Suman, Chikungwa Mose, Earnshaw Greg, Grewal Moni, Haque Shamimul, Hawkins John, Javaid Ahmed, Jackson Clare, Kamel Miriam, Marla Ruchira, Mculloch Dori-Ann, Parker Tom, Salib Yussof, Saravanmuthu Ramesh, Secker Chri, Sockalingam Siva, Taylor Anne, Austine Pauline, Kanade Vrushali, Paal Dora, Sam Mok May Un, Burtenshaw Andrew, Davis Laura, Ellahee Parvez, Freeman David, Pierson Richard, Wollaston Julie, Karmarkar Amara, Ball Clare, Calton Emily, Maxwell Louise, Walker Rachel, Bland Martin, Bullock Lynne, Harrison-Briggs Donna, Hodge Paul, Krige Anton, Dempsey Ged, Hammell Claire, Loveridge Robert, Parker Robert, Snell Jane, Wright Carl, Baker Andy, Barr Katharine, Belcher Alex, Bonnington Sam, Bougeard Anne-Marie, Fitzgerald Emma, Ford Rachael, Gillard Chantal, Griffiths Liz, Greenberg Lizzie, Huber Jonathan, Mathieu Steve, Richardson Neil, Tompsett Laura, White Nigel, Patel Santosh, Corner Victoria, Thomas Richard, Trodd Dawn, Wilson Jennifer, Copley Ed, Flutter Laura, Hulme Jonathan, Susarla Jay, Thwaites Alison, Jayasundera Suraj, Mcafee Sean, Chantler Jonathan, Mckechnie Stuart, Neely Julia, Mouton Ronelle, Scarth Edward, Soar Jasmeet, Buss Joanne, Currie Vicki, Sange Mansoor, Kuttler Anja, Power Fiona, Alexander David, Dunne Kevin, Shinner Guy, Black Euan, Haldane Grant, Kerr Jennie, Saran Taj, Ward Geraldine, Jefferies Fiona, Alexander Peter, Royle Alison, Nahla Farid, Bowles Tim, Gregory Maggie, Ahern Rebecca, Cartlidge David, Craker Lloyd, Thompson Christopher, Bidd Heena, Giles Julian, Manser Amanda, Parry Gareth, Chan Peter, Das Dinesh, Fahmy Nisreen, Higgins David, Khader Ahmed, Stone Alex, Leonardi Silvia, Rose Oliver, Bright Elizabeth, Ercole Ari, Amir Rafi Muhammed, Ramasamy Radhika, Sheshgiri Bengeri, Merrill Colin, Page Valerie, Walker Elaine, Harris Stephen, Hughes Sarah, Morrison Alan, Razouk Khaled, Ayman Mustafa, Jakeman Alicia, Mowatt Chri, Paananen Sami, Supporting clinical sciences, Intensive Care, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service d'anesthésiologie, Surgery, and RS: NUTRIM - R2 - Gut-liver homeostasis
- Subjects
Male ,The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for national and international strategies to improve care for this group of patients ,Hospital admission, Hospital discharge, Intensive care, Length of stay, Surgical mortality ,Epidemiology ,Iron metabolism Pathogenesis and modulation of inflammation [IGMD 7] ,surgery ,Cohort Studies ,Clinical endpoint ,Medicine ,Hospital Mortality ,Hospital discharge ,education.field_of_study ,Mortality rate ,Medicine (all) ,Confounding ,General Medicine ,Middle Aged ,Surgical mortality ,Operative ,Europe ,Hospitalization ,Treatment Outcome ,Surgical Procedures, Operative ,outcomes, surgery, mortality ,Female ,mortality ,cohort study ,Cohort study ,Human ,Adult ,medicine.medical_specialty ,Critical Care ,Population ,MEDLINE ,Settore MED/41 - ANESTESIOLOGIA ,Humans ,ddc:610 ,Mortality ,education ,surgery, mortality, Europe ,Aged ,Postoperative Care ,Surgical Procedures ,business.industry ,Length of Stay ,Hospital admission ,Surgery ,Clinical outcomes ,Intensive care ,Mann–Whitney U test ,Cohort Studie ,business - Abstract
Item does not contain fulltext BACKGROUND: Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. METHODS: We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used chi(2) and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p
- Published
- 2012
81. Stimulus-dependent NETosis by neutrophils from a Papillon-Lefevre Syndrome patient
- Author
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Batinica, M., Stephan, A., Steiger, J., Tantcheva-Poor, I., Eming, S. A., Fabri, M., Batinica, M., Stephan, A., Steiger, J., Tantcheva-Poor, I., Eming, S. A., and Fabri, M.
- Published
- 2017
82. LL37:DNA complexes provide antimicrobial activity against intracellular bacteria in human macrophages
- Author
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J. Steiger, Pia Hartmann, Frank Zaucke, Marina Batinica, Mario Fabri, Alexander Stephan, and Wilhelm Bloch
- Subjects
0301 basic medicine ,Neutrophils ,medicine.medical_treatment ,Immunology ,Antimicrobial peptides ,Intracellular Space ,Biology ,Extracellular Traps ,Neutrophil Activation ,Cathelicidin ,Microbiology ,03 medical and health sciences ,0302 clinical medicine ,Cathelicidins ,Phagosomes ,medicine ,Immunology and Allergy ,Macrophage ,Humans ,Tuberculosis ,Cells, Cultured ,Phagosome ,Intracellular parasite ,Macrophages ,Neutrophil extracellular traps ,Original Articles ,DNA ,Antimicrobial ,Mycobacterium bovis ,Endocytosis ,Immunity, Innate ,030104 developmental biology ,lipids (amino acids, peptides, and proteins) ,Intracellular ,030215 immunology ,Antimicrobial Cationic Peptides - Abstract
As part of the innate host response neutrophils release neutrophil extracellular traps (NETs), protein:DNA complexes that contain a number of antimicrobial peptides (AMPs), such as cathelicidin. Human cathelicidin in its active form, LL37, has potent antimicrobial activity against bacteria. However, whether LL37 derived from NETs contributes to antimicrobial activity against intracellular pathogens remains unclear. Here, we report that NETs induced by mycobacteria contain cathelicidin. Human macrophages internalized NET-bound cathelicidin, which is transported to lysosomal compartments. Furthermore, using a model of in vitro-generated LL37:DNA complexes we found that LL37 derived from such complexes attacks mycobacteria in macrophage phagolysosomes resulting in antimicrobial activity. Taken together, our results suggest a mechanism by which LL37 in complex with DNA contributes to host defence against intracellular bacteria in human macrophages.
- Published
- 2016
83. Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette-Guérin in Glucocorticoid-Treated Human Macrophages
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Lena Pitzler, Matteo Pellegrini, Bent Brachvogel, Robert L. Modlin, Andrea Sommer, J. Steiger, Susan Realegeno, Rainer Kalscheuer, Megan S. Inkeles, Philipp Kröll, Pia Hartmann, Marina Batinica, Mario Fabri, Georg Plum, Juliana de Castro Kroner, Heiko Bruns, Alexander Stephan, and Steffen Stenger
- Subjects
0301 basic medicine ,Vacuolar Proton-Translocating ATPases ,medicine.drug_class ,medicine.medical_treatment ,Cells ,Immunology ,Anti-Inflammatory Agents ,Antitubercular Agents ,Biology ,Antimycobacterial ,Phagolysosome ,Article ,Cathelicidin ,Microbiology ,03 medical and health sciences ,Interferon-gamma ,0302 clinical medicine ,Cathelicidins ,Lysosome ,Phagosomes ,Phagosome maturation ,medicine ,Autophagy ,Immunology and Allergy ,Macrophage ,Humans ,Tuberculosis ,Innate ,Lytic vacuole ,Glucocorticoids ,Cells, Cultured ,Cultured ,Macrophages ,Immunity ,Hydrogen-Ion Concentration ,Mycobacterium bovis ,Immunity, Innate ,030104 developmental biology ,medicine.anatomical_structure ,Gene Expression Regulation ,Imatinib Mesylate ,Glucocorticoid ,030215 immunology ,medicine.drug ,Antimicrobial Cationic Peptides - Abstract
Glucocorticoids are extensively used to treat inflammatory diseases; however, their chronic intake increases the risk for mycobacterial infections. Meanwhile, the effects of glucocorticoids on innate host responses are incompletely understood. In this study, we investigated the direct effects of glucocorticoids on antimycobacterial host defense in primary human macrophages. We found that glucocorticoids triggered the expression of cathelicidin, an antimicrobial critical for antimycobacterial responses, independent of the intracellular vitamin D metabolism. Despite upregulating cathelicidin, glucocorticoids failed to promote macrophage antimycobacterial activity. Gene expression profiles of human macrophages treated with glucocorticoids and/or IFN-γ, which promotes induction of cathelicidin, as well as antimycobacterial activity, were investigated. Using weighted gene coexpression network analysis, we identified a module of highly connected genes that was strongly inversely correlated with glucocorticoid treatment and associated with IFN-γ stimulation. This module was linked to the biological functions autophagy, phagosome maturation, and lytic vacuole/lysosome, and contained the vacuolar H+-ATPase subunit a3, alias TCIRG1, a known antimycobacterial host defense gene, as a top hub gene. We next found that glucocorticoids, in contrast with IFN-γ, failed to trigger expression and phagolysosome recruitment of TCIRG1, as well as to promote lysosome acidification. Finally, we demonstrated that the tyrosine kinase inhibitor imatinib induces lysosome acidification and antimicrobial activity in glucocorticoid-treated macrophages without reversing the anti-inflammatory effects of glucocorticoids. Taken together, we provide evidence that the induction of cathelicidin by glucocorticoids is not sufficient for macrophage antimicrobial activity, and identify the vacuolar H+-ATPase as a potential target for host-directed therapy in the context of glucocorticoid therapy.
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- 2016
84. Salutogeni pristup u promicanju kardiovaskularnog zdravlja
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Batinica, Maja, Grgurić, Josip, and Mladić Batinica, Inga
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salutogeneza ,pozitivno zdravlje ,promicanje zdravlja ,kardiovaskularne bolesti ,prevencija u djetinjstvu - Abstract
SAŽETAK Koncept salutogeneze – „stvaranja zdravlja“, podrazumijeva kontinuum zbivanja od stanja lošeg zdravlja (engl. dis-ease) do potpunog zdravlja (engl. ease), pri čemu je važnije usmjeriti se na resurse koji će pridonijeti stvaranju i održavanju zdravlja, nego se uobičajeno usredotočiti na zdravstvene rizike i bolesti – salutogeneza vs. patogeneza. Salutogenezom se prospektivno razmatra kako razviti, povećati i poboljšati fizičko, psihičko i socijalno blagostanje. Salutogeneza ovisi o koherenciji između pojedinca i njegove okoline. Osobe s primjerenim općim obrambenim mehanizmima mogu, učenjem kroz iskustva, postepeno razviti snažan osjećaj koherencije, što pridonosi zdravlju – naime, veći osjećaj koherencije podrazumijeva bolje zdravlje i kvalitetu života. U razvoju kardiovaskularnih bolesti važnu ulogu imaju emocije, promišljanja i stavovi pojedinca, pridonoseći preuranjenom početku bolesti ili poboljšanju zdravlja. U okviru zdravog stila života, u promicanju kardiovaskularnog zdravlja, uz salutogeni koncept pozitivne psihologije, treba se usmjeriti i na već dobro poznate čimbenike, osobito zdravu prehranu, redovitu tjelesnu aktivnost, primjerenu uhranjenost, te nepušenje. Stil življenja, povezan s osjećajem koherencije (engl. sense of coherence – SOC), jedan je od odlučujućih čimbenika zdravlja.
- Published
- 2014
85. TEŠKI OBLICI KAWASAKIJEVE BOLESTI: ŠOK I SINDROM VIŠESTRUKOG ORGANSKOG ZATAJENJA – PRIKAZ DVAJU BOLESNIKA
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Batinica, Maja, Rešić, Arnes, and Gagro, Alenka
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kawasakijeva bolest, multiplo orgransko zatajanje - Abstract
Uvod: Kawasakijeva bolest (KB) je akutni, samoograničavajući vaskulitis koji se tipično javlja u djetinjstvu. Njezine najvažnije komplikacije su promjene koronarnih arterija, do kojih dolazi u 15 do 25% neliječenih slučajeva. U posljednje se vrijeme izvje- štava o teškim oblicima KB-a, povezanima sa sindromom višestrukog organskog zatajenja (engl. multiple organ dysfunction syndrome - MODS), šokom i s učestalije promijenjenim koronarnim arterijama. U ovom radu prikazujemo dvoje bolesnika s tim obilježjima, liječena u našoj ustanovi. Prikazi bolesnika: Bolesnik 1. Šestogodišnji se dječak prezentirao s akutnim febrilnim faringitisom. Sljedećih dana njegovo se stanje pogoršalo - uslijedio je razvoj generaliziranih edema, hipotenzije i simptoma od strane više organskih sustava: gastro- intestinalnog (proljev, intestinalni edem, peritonealni izljev, hipoalbuminemija), respiratornog (alveolo-intersticijalna pneu- monija s obostranim pleuralnim izljevima), neurološkog (iritabilnost, letargija), kardiovaskularnog (miokarditis, fuziformna aneurizma desne koronarne arterije, dilatacija lijeve koronarne arterije). Iako od prvih dana bolesti hospitalno liječen (u lokal- noj bolnici), KB je dijagnosticiran i specifično liječen 18 dana nakon početnog febriliteta, kad su se evidentirale promjene koronarnih arterija. Retrospektivnoje dječak imao standardne kliničke kriterije za KB (vrućicu ≥5 dana, osip, infekciju konjunktiva, eritematozne, ispucane usnice, vratnu limfadenopatiju te promjene na ekstremitetima), na početku bolesti maskirane, od- nosno uklopljene u kliničku sliku višestrukog organskog zatajenja. Liječen je intravenskim imunoglobulinima (IVIG) i acetil- salicilnom kiselinom (ASA), što je dovelo do brzog kliničkog poboljšanja, uz usporenu regresiju promjena na koronarnim arterijama. Bolesnik 2. Petogodišnja djevojčica prezentirala se s vrućicom, unilateralnom ingvinalnom limfadenopatijom i multiformnim eritemom. Hospitalizirana je prvog dana bolesti. Njezino se stanje ubrzo kompliciralo višestrukim organskim zatajenjem, progredirajući u sindrom šoka. Imala je respiratornu insuficijenciju koja je zahtijevala mehaničku ventilaciju i hipovolemički šok s anasarkomom, pleuralnim, peritonealnim i perikardijalnim izljevom, te je dobivala inotropnu potporu. Od kardiovaskularnih promjena imala je perivaskularni ultrazvučni sjaj (engl. perivascular echo brightness - PEB) obiju koronarnih arterija, s regresijom nakon dvije doze IVIG-a (prvu je dozu dobila četvrtog dana febriliteta) i kortikosteroidne pulsne terapije s visokom dozom ASA-a. Pptpuno se oporavila, bez sekvela. Imala je kriterije za sindrom šoka zbog KB-a (engl. Kawasaki disease shock syndrome - KDSS). Zaključak: Teški oblici KB-a, šok i višestruko organsko zatajenje mogu otežati postavljanje dijagnoze u podlozi. Povezani su s jačom upalnom reakcijom, a mogu biti zahvaćeni svi organi. Liječnici praktičari i oni koji rade u jedinicama intenzivnog liječe- nja trebali bi imati na umu neuobičajene prezentacije KB-a, s obzirom na to da pravodobno, brzo liječenje smanjuje učestalost kardiovaskularnih komplikacija.
- Published
- 2016
86. Kliničke karakteristike adolescenata s esencijalnom hipertenzijom
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Helena Strizić, Vesna Herceg Čavrak, and Maja Batinica
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hipertenzija, esencijalna ,adolescenti ,hypertension, essential ,adolescent - Abstract
Prevalencija primarne arterijske hipertenzije (AH) u djece je u porastu. Iako je hipertenzija u pedijatrijskoj dobi većinom asimptomatska, već se registriraju subkliničke promjene ciljnih organa. Cilj istraživanja je bio analizirati čimbenike rizika za AH i kliničke značajke adolescenata s primarnom hipertenzijom. Retrospektivno su analizirani podatci 153-oje bolesnika u dobi od 10 do 18 godina (117 M, 36 Ž) s dijagnozom primarne AH-a, hospitaliziranih u tercijarnoj zdravstvenoj ustanovi tijekom desetogodišnjeg razdoblja. Razdijeljeni su u tri skupine - djeca s prehipertenzijom, hipertenzijom I. stupnja (HT I.) i hipertenzijom II. stupnja (HT II.). Za statističku analizu primijenjen je Studentov t-test, razina značajnosti p, The prevalence of primary arterial hypertension in children is increasing. Although hypertension in children is mostly asymptomatic, subclinical changes on target organs are already recorded. The aim was to analyze risk factors for arterial hypertension and clinical profi les in adolescents with primary hypertension. Retrospective analysis was performed on 153 children aged 10-18 years (117 M and 36 F) with primary hypertension, hospitalized during a 10-year period. Patients were divided into three groups: prehypertension, stage 1 hypertension and stage 2 hypertension. On statistical analysis, Student’s t-test was used. The level of signifi cance was set at p
- Published
- 2016
87. Kliničke karakteristike adolescenata s esencijalnom hipertenzijom
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Strizić, H, Herceg-Čavrak, V, and Batinica, M
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Kliničke karakteristike ,adolescenti ,esencijalna hipertenzija - Abstract
Prevencija, detekcija i liječenje hipertenzije i pridruženih stanja treba započeti već u dječjoj dobi.
- Published
- 2016
88. Long latency response in laryngeal muscles evoked by mapping with nTMS and DCS of Broca's area - A patient case report
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Rogić Vidaković, Maja, Zmajević Schonwald, Marina, Rotim, Krešimir, Sajko, Tomislav, and Mladić Batinica, Inga
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Long latency response ,laryngeal muscles ,Broca's area ,primary motor cortex ,TMS ,DCS - Abstract
Aim: Mapping of the primary motor cortex (M1) and the Broca’s area was performed preoperatively by navigated transcranial magnetic stimulation (nTMS) and intraoperatively during awake brain surgery by direct cortical stimulation (DCS) in a 44-year-old female patient with an expansive tumor process (glioblastoma) in the fronto-temporal cortex of left hemisphere. This is the first patient in whom both methodologies were performed for detecting motor speech cortical areas. The nTMS methodology was originally developed on healthy subjects, while DCS methodology on patients. Methods: The patient underwent nTMS preoperatively and intraoperatively DCS over the left M1 i.e. muscles of the upper extremities, larynx, and over the Broca’s area in the posterior part of inferior frontal gyrus hemisphere. The motor evoked potentials (MEPs) were recorded from abductor pollicis brevis muscle (APB) and corticobulbar MEPs (CoMEPs) from laryngeal muscle by mapping the M1, while long latency responses (LLRs) were recorded from laryngeal muscle by mapping the Broca’s area. Preoperatively the patient was engaged in visual object naming task, with the stimulation time-locked at 0 ms after picture presentation. Single pulse nTMS was used for mapping the M1 for hand muscle representation, while stimulation protocol consisting of 4 bursts of 4 stimuli each, with an interstimulus interval of 6 ms, and a burst repetition rate of 4 Hz was used for mapping the Broca’s area. Intraoperative stimulation was performed as close to the nTMS makers as possible using the neuronavigation equipment. DCS paradigm of 5 monophasic pulses of 0.4 ms duration, repetition rate of 2, 2 Hz, intensity up to 15 mA was used for eliciting patient clinical response as well as recording CoMEPs, and LLRs. Results: Preoperatively, the latency of CoMEP was 9.14 ms and intraoperatively 5.62 ms. The latency of LLR preoperatively was 54.94 ms, while intraoperatively 37, 4 ms. CoMEP elicited by the stimulation of M1 for laryngeal muscles corresponded to induced dysarthria preoperatively and intraoperatively, while LLR elicited by stimulation of the premotor cortex in the caudal opercular part of inferior frontal gyrus corresponded intraoperatively to semantic paraphasia at the beginning of the surgery, and later on to speech arrest. Conclusion: Mapping of the Broca’s area was successfully performed in patient with both methodologies, nTMS as a part of preoperative neurosurgical planning and with DCS during awake brain surgery. Future reports are needed to establish normative data for nTMS and DCS mappings of Broca’s area on group of patients.
- Published
- 2016
89. Biliary atresia: the Croatian experience 1992–2006
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Ruža Grizelj, Jurica Vuković, Milivoj Novak, and Stipe Batinica
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Male ,medicine.medical_specialty ,Pediatrics ,Croatia ,medicine.medical_treatment ,Portoenterostomy, Hepatic ,Liver transplantation ,Biliary Atresia ,Biliary atresia ,Epidemiology ,medicine ,Humans ,Child ,Survival rate ,Survival analysis ,Retrospective Studies ,business.industry ,Incidence ,Incidence (epidemiology) ,Infant, Newborn ,Infant ,Retrospective cohort study ,Biliary atresia . Children . Incidence . Kasai portoenterostomy ,medicine.disease ,Survival Analysis ,Liver Transplantation ,Surgery ,Biliary Tract Surgical Procedures ,Treatment Outcome ,Biliary tract ,Pediatrics, Perinatology and Child Health ,Female ,business ,Follow-Up Studies - Abstract
The objective of this study was to determine the outcomes of Croatian children with biliary atresia. Health records of infants born in Croatia between January 1, 1992 and December 31, 2006 who were diagnosed with biliary atresia and treated at a single university center were reviewed. Survival rates were calculated with the Kaplan–Meier method. Twenty-nine patients with biliary atresia were identified. Incidence was one in 23, 600 live births (95% confidence interval 1/17, 400–1/27, 200). The median age at Kasai operation was 66 days (range 22–192). Median follow-up was 2.65 years (range 0.2–14.3). Overall survival rates for the patients who underwent Kasai portoenterostomy, including those six (20%) who subsequently underwent liver transplantation, were 75.6%. Five and 10-year native liver survival rates were 51.7% and 38.8%, respectively (median survival time was 7.88 years). Survival rate curves in two groups of patients according to the biliary atresia phenotype (fetal or perinatal form) were divergent. Survival was 87.7% in perinatal form and 43.8% in fetal form (Breslow chi-square 8.082, p
- Published
- 2010
90. Cytological detection of lymphoma in Douglas aspirate
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Anita Grgurević Batinica M.D., Mirna Sučić, Nives Ljubić, Nada Lang, Ljiljanka Jurković, Mara Dominis, Ankica Vasilj M.D., and Zoran Šiftar
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Adult ,lymphoplasmacytic lymphoma ,effusion ,cytomorphology ,immunocytochemistry ,Pathology ,medicine.medical_specialty ,Histology ,Pathology and Forensic Medicine ,Lymphoplasmacytic Lymphoma ,Douglas' Pouch ,immune system diseases ,hemic and lymphatic diseases ,medicine ,Humans ,Cell Proliferation ,CD20 ,biology ,business.industry ,Biopsy, Needle ,Waldenstrom macroglobulinemia ,Cell Differentiation ,General Medicine ,medicine.disease ,Lymphoma ,Ileal Neoplasms ,Serous fluid ,medicine.anatomical_structure ,Effusion ,biology.protein ,Female ,Bone marrow ,Primary effusion lymphoma ,Waldenstrom Macroglobulinemia ,business - Abstract
Except in primary effusion lymphoma (PEL), serous effusions with lymphomatous cells in non-Hodgkin lymphoma (NHL) are not frequently seen as first manifestation of disease. In NHL lymphoplasmacytic lymphoma (LPL) the spleen, lymph nodes, and bone marrow are frequently sites of disease and this type of NHL is usually associated with a serum paraprotein of IgM type accompanied by the clinical syndrome of Waldenström macroglobulinemia. Our patient with NHL LPL type presented in this report had less frequently seen involvement of gastrointestinal tract and clinically was first manifested as effusion in Douglas space. Cytological evaluation as well immunoanalyses of effusion in such cases is essential, and various ancillary studies, because of differential diagnostic problems of lymphomas in serous effusions, first include reactive lymphocytoses and small round-cell tumors (SRCT). In our patient, cytology of effusion revealed cytomorphologically atypical lymphomatous cells with plasmocytoid differentiation. Immunocytochemical and flow cytometry analysis confirmed lymphoid cell differentiation and pathohistological diagnosis of CD20(+) LPL was set after pathohistological analysis of resected ileum.
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- 2008
91. Awake craniotomy - the anaesthesiologist´s view
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Mladić Batinica, Inga, primary
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- 2017
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92. Speech brain mapping by direct cortical stimulation during the awake craniotomy and possible increase in sympathetic activity: a case report
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Mladić Batinica, Inga, primary
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- 2017
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93. Blood pressure in adolescent athletes on regular checkup
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Batinica, Maja, primary, Alić, Ariana, additional, and Božikov, Jadranka, additional
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- 2017
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94. Speech Disturbance during Subcortical Mapping in Surgery for Right Superior Frontal Gyrus Glioma in Awake Patient
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I. Šumonja, Tomislav Sajko, Krešimir Rotim, M. Zmajević, and I. Mladić-Batinica
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Disturbance (geology) ,business.industry ,Glioma ,Anesthesia ,Medicine ,Surgery ,Neurology (clinical) ,business ,Left superior frontal gyrus ,medicine.disease - Published
- 2015
95. Positive Intraoperative Changes of Muscle Motor Evoked Potentials in Patients with Intramedullary Cervicospinal Tumors
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Željko Hamata, Inga Mladić Batinica, Maja Rogić Vidaković, Krešimir Rotim, Marina Zmajević Schönwald, and Rohde, V.
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Intramedullary rod ,medicine.medical_specialty ,Pathology ,business.industry ,law ,Medicine ,Surgery ,In patient ,Neurology (clinical) ,business ,muscle motor evoked potentials ,intramedullar cervicospinal tumors ,law.invention - Abstract
Intraoperative motor evoked potentials (MEPs) recorded as muscle motor evoked responses (MMEPs) and D wave are performed to avoid corticospinal tract (CST) lesions in spinal surgery. Not only CST but also the collaborative pathways play the significant role in conduction of evoked motor impulses. Using MMEPs, we can monitor the complete motor networking response. Patients (17), 10 males and 7 females with significant motor deficit (tetraparesis or paraparesis), due to intramedullary spinal tumor located within the C2 to Th11 spinal levels, were operated on. In selected muscles, we measured muscle strength deficit preoperatively and postoperatively using Medical Research Council Scale (MRCS). During the neuromonitoring, we performed transcranial electrical stimulation (C3–C4/C4–C3) using short train stimuli technique while recording D wave, and MMEPs. For MMEPs recording, we used needle electrodes inserted preoperatively during patients' voluntary muscle contraction. We measured MMEP parameters and D wave, using unchanged low-threshold stimulation, at 6 points during the surgery. During the middle part of tumor resection, we recorded the gradual rise in MMEP amplitude, duration, and number of phases, especially for hand and foot muscles, but unchanged D wave values. At the end of the tumor resection, we measured MMEP values again, and obtained the same results. Postoperatively, in 7 days' time, muscle strength of our patients improved, and was measured one point higher on the MRC-S, compared with the preoperative findings. The changes of MMEPs parameters during the tumor resection were good predictors of positive postoperative results. D wave remains reliable indicator of complete CST function. However, intraoperatively recorded improved MMEP values, with unchanged D wave, support the theory of alternative pathways connected with motoneurons. The influence of these pathways on evoked motor contraction seems to produce improved postoperative motor status later on.
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- 2015
96. Bug or no bug: challenges in diagnosing cutaneous mycobacterial infections
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Franziska, Peters, Marina, Batinica, Georg, Plum, Sabine A, Eming, and Mario, Fabri
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Diagnosis, Differential ,Evidence-Based Medicine ,Fungi ,Dermatomycoses ,Humans ,Reproducibility of Results ,Diagnostic Errors ,Mycological Typing Techniques ,Polymerase Chain Reaction ,Sensitivity and Specificity ,Skin - Abstract
Cutaneous mycobacterioses are rare in Germany. Nevertheless, early diagnosis and subsequent effective treatment requires awareness of these conditions. Moreover, mycobacterial infections are on the differential diagnosis list of many skin diseases. Diagnoses of cutaneous mycobacterioses are based on clinical features, but also on laboratory investigations, including bacterial culture, histopathology and PCR-based methods. Knowledge about the opportunities and limitations of theses laboratory tests is pivotal to reasonable clinical decision-making. In this paper, we review the current diagnostic options when suspecting a case of cutaneous mycobacterial infection.
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- 2015
97. Keim oder kein Keim: Herausforderungen bei der Diagnose mykobakterieller Infektionen der Haut
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Franziska, Peters, Marina, Batinica, Georg, Plum, Sabine A, Eming, and Mario, Fabri
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Kutane Mykobakteriosen sind in Deutschland selten. Dennoch ist es für eine frühzeitige Diagnose und anschließende wirksame Behandlung erforderlich, dass diese Krankheitsbilder im ärztlichen Bewusstsein verankert sind. Darüber hinaus stehen Infektionen mit Mykobakterien auf der Liste der Differentialdiagnosen vieler Hautkrankheiten. Diagnosen kutaner Mykobakteriosen beruhen auf klinischen Merkmalen und auf Laboruntersuchungen, einschließlich bakterieller Kulturen, histopathologischer Untersuchungen und PCR-basierten Verfahren. Das Wissen um Möglichkeiten und Grenzen dieser Laboruntersuchungen ist von zentraler Bedeutung, um eine angemessene klinische Entscheidung zu treffen. In diesem Beitrag diskutieren wir die aktuellen diagnostischen Möglichkeiten, die in Verdachtsfällen kutaner Mykobakteriosen zur Verfügung stehen.
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- 2015
98. Keim oder kein Keim: Herausforderungen bei der Diagnose mykobakterieller Infektionen der Haut
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Peters, Franziska, primary, Batinica, Marina, additional, Plum, Georg, additional, Eming, Sabine A., additional, and Fabri, Mario, additional
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- 2016
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99. Biped walking and stairs climbing using reconfigurable adaptive motion primitives
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Rakovic, Mirko, primary, Borovac, Branislav, additional, Santos-Victor, Jose, additional, Batinica, Aleksandar, additional, Nikolic, Milutin, additional, and Savic, Srdan, additional
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- 2016
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100. [Chronic disease and health condition prevention in childhood--2nd part: emphases from the 14th Symposium of Preventive Pediatrics]
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Maja Batinica, Josip Grgurić, and Filip Jadrijević-Cvrlje
- Subjects
Biomedical Research ,Chronic Disease ,Preventive Health Services ,Quality of Life ,Humans ,Kronična bolest – epidemiologija, klasifikacija, prevencija i kontrola ,Pedijatrija – tendencija, metode ,Dje~ja zdravstvena zaštita – metode ,Preventivna zdravstvena služba – metode ,Skrb za djecu ,Chronic disease – epidemiology, classification, prevention and control ,Pediatrics – trends, methods ,Child health services – methods ,Preventive health services – methods ,Child welfare ,Child ,Pediatrics - Abstract
Kronično bolesne djece danas je u razvijenim društvima sve više, a zbog modernih terapijskih mogućnosti sve više djece preživljava do odrasle dobi. Duži životni vijek ne znači nužno i bolju kakvoću života. S kronično bolesnim djetetom važan je holistički pristup koji uključuje ne samo ostvarivanje najviših mogućih standarda u dijagnostici i liječenju već i posebnu brigu za prevenciju bolesti. Sve je to važno u tzv. integrativnom pristupu u pomoći djetetu s kroničnim poremećajem, s ciljem postizanja što bolje kakvoće života i što potpunije socijalne integracije. Na XIV. simpoziju preventivne pedijatrije, održanom u Skradu 1. lipnja 2013., razmatrani su, s preventivnoga gledišta, ovi kronični poremećaji u dječjoj dobi: poremećaj pozornosti s hiperaktivnošću, migrenozne glavobolje, bolesti štitnjače, leukemije, cistična fibroza, kronična bubrežna bolest, kronične upalne bolesti jetre, kronične upalne bolesti crijeva, juvenilni idiopatski artritis te kronični sekretorni otitis. Naglašeno je da kada se govori o prevenciji, prilikom razmatranja određene bolesti na umu treba imati tri oblika prevencije – primarnu, sekundarnu i tercijarnu, a to znači: kako smanjiti pojavnost bolesti, kako je rano otkriti i ispravno liječiti te naposljetku kako poboljšati kakvoću života djeteta s kroničnom bolesti. Kvartarna prevencija, s ciljem smanjenja polipragmazije, uključuje mjere za ublažavanje ili izbjegavanje rezultata nepotrebnih ili suvišnih intervencija zdravstvenog sustava. Važan je proces i prijenos skrbi o pacijentu iz dječje dobi u odraslu dob. U odrasloj dobi važan je nastavak praćenja i nadzor kroničnog stanja, zbog mogućeg razvoja kasnih posljedica kronične bolesti u djetinjstvu., Chronically ill children nowdays in developed countries are more prevalent than before, and thanks to modern therapeutic modalities more children are surviving into adulthood. Increased survival cannot be assumed to be associated with increased quality of life. With the chronically ill child holistic approach is important, which incorporates not only realisation of the highest possible standards in diagnostics and treatment, but also special care for disease prevention. All this is very important in so called integrative approach in the care of a chronically ill child, with the aim of achieving as high as possible quality of life and complete social integration. At the 14th Preventive Pediatrics Symposium, which took place in Skrad, June 1st 2013, from preventive standpoint, the following chronic childhood illnesses were discussed: attention deficit hyperactivity disorder – ADHD, migraine, thyroid gland diseases, leukemia, cystic fibrosis, chronic renal disease, chronic inflammatory liver disease, chronic inflammatory bowel disease, juvenile idiopathic arthritis, and chronic otitis media with effusion. It is emphasized that talking about a disease prevention, there are three levels of it – primary, secondary and tertiary prevention: how to avoid occurrence of disease, how to diagnose and treat existent disease in early stages, before it causes significant morbidity, and finally how to reduce the negative impact of existent disease by restoring function and reducing disease-related complications – how to improve quality of life of children with chronic diseases. Quaternary prevention describes methods to mitigate or avoid results of unnecessary or excessive interventions of the health system. An important process is also transition of care from child-oriented to adult-oriented care. Adults with chronic health conditions should continue to be evaluated periodically for possible late consequences of their childhood illness and previous medical treatments.
- Published
- 2015
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