56 results on '"Ashour, Z"'
Search Results
52. Value of conventional and tissue Doppler echocardiography in the noninvasive measurement of right atrial pressure.
- Author
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Said K, Shehata A, Ashour Z, and El-Tobgi S
- Subjects
- Female, Humans, Male, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Algorithms, Atrial Function, Right, Atrial Pressure, Echocardiography, Doppler methods, Elasticity Imaging Techniques methods, Image Interpretation, Computer-Assisted methods
- Abstract
Background: Evaluation of right atrial pressure (RAP) provides useful diagnostic, therapeutic, and prognostic information., Aim: To assess the utility of several conventional and tissue Doppler parameters in the estimation of RAP., Methods: Among 50 consecutive patients (median age: 50 years; all in sinus rhythm), invasively measured RAP was simultaneously correlated with pulsed Doppler of tricuspid inflow (peak E and A velocities, E-wave deceleration time) and pulsed tissue Doppler of lateral tricuspid annulus (peak E' and A' velocities, isovolumic relaxation time [IVRT], acceleration time and rate of E'-wave, deceleration time and rate of E'-wave). These ratios were calculated: E/A, E'/A', E/E', and E/IVRT., Results: The median RAP was 14 mmHg (range 1-27 mmHg) with 29 patients (58%) having an elevated RAP (>10 mmHg). Among all studied Doppler variables, E/E' ratio showed the strongest correlation with RAP (r = 0.84, P < 0.001) with the following regression equations: RAP = 1.24 + (1.69 × E/E'). The mean difference between Doppler and invasively measured RAP was 0.21 ± 2.6 mmHg. E/ E' ratio ≥ 4.5 provides 89% sensitivity and 100% specificity for detection of elevated RAP (receiver operating characteristic area 0.95; P < 0.001)., Conclusion: Of all echocardiographic variables investigated, tricuspid annular E/E' ratio is identified as the best index for noninvasive determination of RAP., (© 2012, Wiley Periodicals, Inc.)
- Published
- 2012
- Full Text
- View/download PDF
53. Low-grade endometrial stromal sarcoma with intravenous extension to the heart.
- Author
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Gabal S, Ashour Z, Hamada G, Aziz SA, Khairy H, Badawy H, Hamada EM, and Saied K
- Subjects
- Endometrial Neoplasms surgery, Female, Heart Neoplasms surgery, Humans, Sarcoma, Endometrial Stromal surgery, Young Adult, Endometrial Neoplasms diagnosis, Heart Neoplasms diagnosis, Heart Neoplasms secondary, Sarcoma, Endometrial Stromal diagnosis
- Abstract
Endometrial stromal sarcoma (ESS) is a rare neoplasm of uterine origin. Intracardiac metastasis from this tumor is extremely infrequent. This report describes a 24-year-old woman from Yemen who had irregular vaginal bleeding shortly after spontaneous abortion. She developed left-lower-limb swelling, diagnosed by duplex scanning and magnetic resonance imaging as deep venous thrombosis in the inferior vena cava (IVC) that extended into the iliac veins on both sides, as well as the left femoral vein and right atrium. She developed acute respiratory distress, from which she recovered after transfer to the intensive care unit. Transesophageal echocardiography showed a large mass occupying the right atrium and ventricle and another mass in the right ventricular outflow tract with areas of cavitations. The tumor appeared to come from the IVC and extended through the right atrium and right ventricle into the pulmonary artery, ending in several digit-like projections. After surgical resection of the intracardiac mass, pathologic examination revealed a low-grade ESS that was confirmed by immunohistochemistry. The patient underwent panhysterectomy and IVC debridement. Pathologic examination revealed infiltrating low-grade endometrial sarcoma invading the myometrium and left adnexa, with intravenous extension into the pelvic veins and the IVC to the right side of the heart. This case shows that despite its well-known good prognostic nature, low-grade ESS may behave as an aggressive malignancy.
- Published
- 2009
54. Relationship between skin color and blood pressure in egyptian adults: results from the national hypertension project.
- Author
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Mosley JD, Appel LJ, Ashour Z, Coresh J, Whelton PK, and Ibrahim MM
- Subjects
- Adult, Age Factors, Body Mass Index, Diastole, Egypt epidemiology, Female, Humans, Hypertension epidemiology, Male, Melanins analysis, Middle Aged, Multivariate Analysis, Prevalence, Systole, Blood Pressure physiology, Hypertension physiopathology, Skin Pigmentation physiology
- Abstract
In many, but not all societies, dark skin color is associated with high blood pressure. Whether the association between skin color and blood pressure is independent of known determinants of blood pressure remains controversial. We examined the association between skin color and blood pressure in 835 Egyptian adults (370 men and 465 women) participating in the National Hypertension Project, a national survey of hypertension prevalence and blood pressure-related complications conducted in Egypt during 1991-1993. Skin color was assessed by measuring the concentration of cutaneous melanin in an unexposed area with the use of reflectance spectrophotometry. Higher concentrations of melanin were associated with lower body mass index, less education, manual labor (among men), and a lower urinary sodium-to-potassium ratio (among women). In multivariate regression analyses adjusted for age, body mass index, and education, there was a significant nonlinear association between blood pressure and skin color among women; in the lower to intermediate range of skin pigmentation, both systolic and diastolic blood pressures were higher in women with greater concentrations of cutaneous melanin. In men, blood pressure was not associated with skin color. When we used a subjective assessment of skin color, there was no significant difference in blood pressure between black-skinned Egyptians (predominantly of Nubian descent) and fair-skinned Egyptians for either gender. While the significant relationship in women appeared to be independent of known risk factors for hypertension, residual confounding may explain the association.
- Published
- 2000
- Full Text
- View/download PDF
55. Outcome of pregnancy in women with mechanical valves.
- Author
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Ashour ZA, Shawky HA, and Hassan Hussein M
- Subjects
- Adult, Anticoagulants adverse effects, Anticoagulants therapeutic use, Female, Fetal Death etiology, Heparin therapeutic use, Humans, Infant, Newborn, Middle Aged, Parity, Pregnancy, Pregnancy Complications etiology, Pregnancy Complications, Hematologic prevention & control, Prospective Studies, Thromboembolism prevention & control, Tricuspid Valve surgery, Warfarin therapeutic use, Heart Valve Prosthesis Implantation adverse effects, Pregnancy Outcome
- Abstract
In women who have prosthetic heart valves, pregnancy is risky for mother and fetus. Heparin has been considered safer for the fetus than warfarin, but may not provide adequate anticoagulation for the mother. We examined prospectively gathered data from 100 pregnancies in 67 women with mechanical valves (age range, 19 to 45 years). A subgroup of 20 patients was compared with a control group of relatives and neighbors who conceived at similar ages. Fetal loss occurred in 44 of the 100 pregnancies, due to the following causes: spontaneous abortion (28), intrauterine fetal death (4), stillbirth (3), neonatal death (1), premature birth (2), Rh incompatibility (2), and maternal death (4). Age, parity, atrial fibrillation, and left ventricular enlargement did not affect the outcome. Tricuspid valve disease that required diuretics was associated with a higher rate of fetal loss (17 out of 23 pregnancies, versus 27 out of 77; p = 0.001), but did not affect the mother Of 66 pregnancies in which the mother was on heparin, 38 (576%) resulted in a healthy baby, compared with 18 out of 34 (52.9%) pregnancies in which the mother was on warfarin (p = NS). All thromboembolic complications occurred with heparin therapy (9 cases; p = 0.02). In the control group, fetal loss was 24 %, due exclusively to spontaneous abortion. Women with mechanical valves have higher rates of fetal loss and maternal complications. In our study, tricuspid valve disease adversely affected fetal outcome, which is a new finding that warrants further study. Warfarin was more effective than heparin in preventing thromboembolism in the mothers, and it did not show a significant impact on the babies.
- Published
- 2000
56. [Effect of reduced arterial compliance on the diastolic function of the heart].
- Author
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Ashour ZA, el Said G, Gharieb S, and Enein SA
- Subjects
- Adult, Aged, Blood Flow Velocity, Compliance, Echocardiography, Doppler, Female, Humans, Male, Middle Aged, Pulsatile Flow, Regression Analysis, Arteries physiology, Diastole physiology, Hypertension physiopathology
- Abstract
Background and Objective: Reduced arterial compliance is associated with age, hypertension and left ventricular hypertrophy. It is unclear if and how reduced arterial compliance affects the diastolic properties of the heart., Patient Population: We examined 64 normotensive and 27 hypertensive individuals, (31 females, 60 males). Their ages ranged from 19 to 78 years (mean 43 +/- 14.7 y), BP ranged from 80/50 to 180/110 mmHg. Exclusion criteria were atrial fibrillation, coronary or peripheral vascular disease, diabetes, anemia, hypercholesterolaemia, as well as antihypertensive drug therapy., Methods: Diastolic function was assessed by Doppler measurement of E and A wave velocities of Mitral flow. E acceleration and deceleration slopes and times. LV mass was calculated from an M- mode echocardiogram. Arterial compliance was assessed by an automatic pulse wave velocity (PWV) measurement., Results: Age and PWV correlated significantly with the mitral E and A waves, the E acceleration time. E deceleration and E deceleration time. No significant correlations were found between SBP, DBP or LV mass and the parameters of diastolic function (see table).
- Published
- 1998
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