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Reseña del libro: Barrientos Márquez, María del Mar y Lozano Salado, Lola (eds.). Revolución y Diplomacia: el Trienio Liberal y América. Santiago de Chile, Ariadna, 2023, 166 pp. ISBN: 978-95-66095-92-7.

Con la llegada a América, decenas de animales fueron traídos a Europa como alimento, pero sobre todo como mascotas exóticas. Su presencia en jardines y cámaras de maravillas pronto despertó la curiosidad de científicos y artistas, que incluyeron estas nuevas especies en sus libros y cuadros. En el caso de los artistas, su representación estuvo fuertemente condicionada por la presencia previa o no de especies de la misma familia. Para mostrar las diferencias según el caso y la red de significados y usos otorgados en el arte a las distintas especies americanas, tomaremos los loros como ejemplo de una familia conocida desde la Antigüedad por los europeos y los armadillos como muestra de una familia desconocida en el Viejo Continente.

It has been almost a century since James Truslow Adams’ formulation of the concept “American dream” in “The Epic of America” (1931). The review aims to follow the concept of the American dream and its evolution over centuries, encompassing the attainment of such core values as freedom, equal opportunity, and the search for happiness. It has been established that at the heart of this notion lies the belief that the United States offers boundless possibilities to those with determination, courage, and audacity to pursue their dreams, relying on hard work and risk-taking rather than mere luck or chance. An integral facet of American “mythology” is highlighted - each individual’s capacity to achieve their dreams and secure a comfortable lifestyle through diligent effort and self-sacrifice, propagating the idea that everyone can be successful. It is concluded that an expression dedicated to this social accomplishment is “to go from rags to riches,” encapsulating this journey.

The invasion of fall armyworm (FAW) to the Eastern hemisphere poses a major challenge to the food security efforts of several nations including India. Invasive FAW population is primarily composed of two predominant strains differentiated based on the mitochondrial cytochrome c oxidase (COI) gene, known as COI-RS (hybrid strain) and COI-CS (corn strain). COI-RS, in particular was found to be different from the ancestral rice strain in America and displayed characteristics of typical inter-strain hybrid population. Although the ancestral populations have been tested for their mating behaviour and response toward pheromones and biocontrol agents, similar studies have not been performed on the invasive populations. We report here the interstrain mating behaviour of COI-RS and COI-CS populations from India along with their susceptibilities towards different biocontrol agents. COI-RS larvae were more susceptible to SpfrNPV infection compared to COI-CS larvae. The response towards other biocontrol agents was similar in the two strains. Electroantennogram response study revealed that the two strains differed in their response towards FAW pheromone, where COICS males displayed higher mean antennal response towards Z-9-tetradecenyl acetate (87%), Z-11-hexadecenyl acetate (12.5%) and Z-7-dodecenyl acetate (0.5%) than COI-RS males. Similar to the ancestral population, we found unidirectional mating between COI-RS females and COI-CS males while the reverse cross did not yield viable offspring. However, further detailed studies are required to confirm this observation. [ABSTRACT FROM AUTHOR]

The credo of the generalist physician has always been the promotion of health for all, in every aspect: not just multiple vulnerable organ systems, but multiple social, cultural, and political factors that contribute to poor health and exacerbate health inequity. In recent years, the field of global health has also adopted this same mission: working across both national and clinical specialty borders to improve health for all and end health disparities worldwide. Yet within the Society for General Internal Medicine, and among American generalists, engagement in global health, both within and outside the USA, remains uncommon. We see this gap as an opportunity, because in fact generalists in America already have the skills and experience that global health badly needs. SGIM could promote generalists to global health's vanguard, with three core steps. First, we generalists must continue to integrate health for the vulnerable into our domestic work, generating care models applicable in low-resource settings around the globe. Conversely, we must also engage with and implement international ideas and solutions for universal access to primary care for vulnerable patients in the USA. And lastly, we must build platforms to connect ourselves with colleagues worldwide to exchange these learnings. [ABSTRACT FROM AUTHOR]

Objectives: The weight-adjusted waist circumference index (WWI), a novel obesity indicator, gives better accuracy in assessing both muscle and fat mass. Our goal was to evaluate the relationship between WWI and the occurrence of hyperuricemia/gout among middle-aged and older adults in America. Methods: We analyzed the National Health and Nutrition Examination Survey (NHANES) data from the 2007–2014 cycles. Logistic regression analyses, subgroup analyses, and restricted cubic splines (RCS) were performed to evaluate the association between WWI and hyperuricemia/gout prevalence. Results: A total of 5332 adults aged 50 years and above were included in this study. The prevalence of hyperuricemia and gout was 23.20% and 6.70% respectively. The fourth quartile of WWI was associated with a 56% higher risk for hyperuricemia, compared with the first quartile (OR = 1.56, 95% CI 1.07–2.27, P trend < 0.001). A similar association was found between continuous WWI increase and OR of hyperuricemia in the fully adjusted model (OR = 1.35, 95% CI = 1.13–1.61, P < 0.05). However, WWI was not significantly associated with the prevalence of gout. The RCS model suggested a significant linear relationship between WWI and the risk of hyperuricemia/gout. Stratification analysis showed that the positive associations of WWI with the risk of hyperuricemia were more pronounced in participants who were women, aged 50–59, smokers, no physical activity, non-diabetes, hypertension, and hyperlipidemia. Conclusions: Our findings suggest a positive correlation between WWI and hyperuricemia among middle-aged and older adults in America. Employing WWI as a tool for hyperuricemia prevention may be meaningful. Key Points • Weight-adjusted waist circumference index is a new obesity evaluation index. • Weight-adjusted waist circumference index is associated with hyperuricemia not gout. • The association is more pronounced in participants who were women, aged 50–59, smokers, no physical activity, non-diabetes, hypertension, and hyperlipidemia. [ABSTRACT FROM AUTHOR]

America's juvenile justice system was founded on the notion that the juvenile court would serve as the "ultimate parent" for youth. Yet, the history of youth punishment challenges the promise of juvenile "justice." To offer a more comprehensive account of the family systems in juvenile court, this study draws from the insights of historical research on youth punishment and family criminalization to examine juvenile court outcomes in Arizona. Combining a historical lens with insights from attribution theory, we use quantitative and qualitative methods to examine the relationship between diverse family systems, including single mothers, single fathers, extended families, and foster care families, and juvenile court outcomes (i.e., diversion, preadjudication detention, petition, and judicial dismissal). Our findings suggest the need for more complex understandings of both family and punishment, and more expansive theorizations of the sorts of solutions that match the scope and scale of the problem. [ABSTRACT FROM AUTHOR]

The lingering influence of the Homeowners’ Loan Corporation (HOLC), a programme established during the 1930s as part of the New Deal, persists in creating a barrier that prevents progress for marginalised communities [Faber, J. 2020. “We Built This: Consequences of New Deal Era Intervention in America’s Racial Geography.” American Sociological Review 85 (5): 739–775. https://doi.org/10.1177/000312242094846]. Particularly notable is the urban heat island phenomenon, currently evident in numerous metropolitan areas nationwide, which disproportionately impacts neighbourhoods that were redlined due to the historical HOLC rankings and subsequent lack of financial investments. This study undertakes a comparative and analytical examination of temperature variations within HOLC-designated zones in Houston, Texas. It employs basic social indicators and evaluates tree canopy density through analysis of variance. Furthermore, spatial regression modelling is employed to mitigate temperature differentials between neighbourhoods characterised by urban tree canopy, especially focusing on the contrast between “A” and “D” zones. In addition, drawing on the statistical parameters derived from estimation, the study's scenario analysis uncovers that a 54% augmentation in tree canopy density within “D” zones would effectively establish thermal equity. As a result, elevating tree canopy density emerges as a strategy to curtail temperature discrepancies while concurrently introducing cooling impacts on surrounding districts. The dataset utilised for the study encompasses satellite-derived urban temperature records, spatially extensive data on tree canopy density, vulnerability insights from the U.S. Census Bureau, and demographic data, including the proportion of African American residents primarily concentrated in “D” graded districts. Thus, this study not only holds potential for enhancing circumstances within marginalised communities but also introduces a pathway to cultivate an enabling environment for all residents. [ABSTRACT FROM AUTHOR]

The triglyceride-glucose (TyG) index is a novel marker of insulin resistance that has been strongly associated with many diseases related to metabolic disorders, such as diabetes, coronary heart disease, myocardial infarction, obesity, nonalcoholic fatty liver disease, and stroke. However, whether the TyG index is associated with the prevalence of gallstones has not been determined. Therefore, the purpose of this study was to evaluate the relationship between the TyG index and the prevalence of gallstones in American adults, as well as the age at which adults in America undergo their first gallstone surgery. We selected individuals from the National Health and Nutrition Examination Survey (NHANES) database from 2017 to March 2020. Based on the goal of our study, comprehensive inclusion and exclusion criteria were created. A logistic regression analysis, dose–response curve, and subgroup analysis were computed to assess the relationship between the TyG index and gallstone prevalence and age at first surgery for gallstone. A total of 3905 participants aged > 20 years were included in our study, of whom 421 had a self-reported history of gallstones. A total of 1884 (48.2%) males and 2021 (51.8%) females were included. After confounders adjustment, it was found single-unit increases in the TyG index were linked with a 25.0% increase in gallstone prevalence (odds ratio [OR] = 1.25, 95% confidence interval [95%CI]: 1.04, 1.51). After conversion of the TyG index values from continuous to categorical variables with tertiles, a marked 48% increase in gallstone incidence was found in tertile 3 relative to tertile 1 (OR = 1.48, 95% CI: 1.09, 1.99). The dose–response curve results indicated positive associations between gallstone prevalence and the TyG index, while the latter was negatively associated with age at first gallstone surgery. Based on subgroup analysis, the positive association between TyG index and high-incidence of gallstones was more significant in females (OR = 1.39, 95% CI: 1.09, 1.77), age < 40 years (OR = 2.02, 95% CI: 1.23, 3.29), and other race (OR = 1.46, 95% CI: 1.06, 2.02). A higher TyG index is associated with a higher incidence of gallstones and may lead to an earlier age of first gallstone surgery. However, a causal relationship between TyG and gallstones cannot be established. [ABSTRACT FROM AUTHOR]

Background: Bariatric surgery can lead to short-mid-term vitamin deficiencies, but the long-term vitamin deficiencies is unclear. This study aimed to conduct a meta-analysis regarding the long-term prevalence (≥ 5 years) of vitamin deficiencies after bariatric surgery. Methods: We searched the EMBASE, PubMed, and CENTRAL databases for clinical studies until June 2023. Meta-analysis, sensitivity, subgroup, and meta-regression analyses were performed. Results: This meta-analysis included 54 articles with follow-up duration ranging from 5 to 17 years. The most prevalent vitamin deficiencies after surgery were vitamin D (35.8%), followed by vitamin E (16.5%), vitamin A (13.4%), vitamin K (9.6%), and vitamin B12 (8.5%). Subgroup analyses showed that the prevalence of vitamin A and folate deficiencies increased with the follow-up time. Roux-en-Y gastric bypass had a higher rate of vitamin B12 deficiency than sleeve gastrectomy and biliopancreatic diversion with duodenal switch (BPD-DS). Studies conducted in Europe had higher vitamin A deficiency (25.8%) than in America (0.8%); Asian studies had more vitamin B12 but less vitamin D deficiency than European and American studies. Meta-regression analysis displayed that publication year, study design, preoperative age, BMI, and quality assessment score were not associated with vitamin A, B12, D, and folate deficiencies rate. Conclusion: A high prevalence of vitamin deficiencies was found after bariatric surgery in the long-term follow-up, especially vitamin D, E, A, K, and B12. The variation in study regions, surgical procedures, and follow-up time are associated with different postoperative vitamin deficiencies; it is necessary to develop more targeted vitamin supplement programs. [ABSTRACT FROM AUTHOR]

Background/Objectives: The purpose of this systematic review was to assess the global prevalence of sleep bruxism and awake bruxism in pediatric and adult populations. Methods: This systematic review was conducted by analyzing studies published from 2003 to 2023. The following keyword combination was utilized: prevalence, epidemiology, population, and bruxism. The PubMed database was analyzed, supplemented by manual searches using the Google search. Additionally, the snowballing procedure method was applied. A double assessment of the quality of publications was carried out to preserve the highest possible quality of evidence (e.g., Joanna Briggs Institute critical appraisal checklist). Analyses were conducted using the R statistical language. Results: The global bruxism (sleep and awake) prevalence is 22.22%. The global sleep bruxism prevalence is 21% and awake prevalence is 23%. The occurrence of sleep bruxism, based on polysomnography, was estimated at 43%. The highest prevalence of sleep bruxism was observed in North America at 31%, followed by South America at 23%, Europe at 21%, and Asia at 19%. The prevalence of awake bruxism was highest in South America at 30%, followed by Asia at 25% and Europe at 18%. Conclusions: One in four individuals may experience awake bruxism. Bruxism is a significant factor among women. It was observed that age is a significant factor for the occurrence of sleep bruxism in women. Among the limitations of the study is the lack of analysis of the prevalence of bruxism in Africa and Australia due to not collecting an adequate sample for analysis. The study was registered in the Open Science Framework (10.17605/OSF.IO/ZE786). [ABSTRACT FROM AUTHOR]

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Background: Since the Coronavirus disease 2019 (COVID-19) pandemic began, the number of individuals recovering from COVID-19 infection have increased. Post-COVID Syndrome, or PCS, which is defined as signs and symptoms that develop during or after infection in line with COVID-19, continue beyond 12 weeks, and are not explained by an alternative diagnosis, has also gained attention. We systematically reviewed and determined the pooled prevalence estimate of PCS worldwide based on published literature. Methods: Relevant articles from the Web of Science, Scopus, PubMed, Cochrane Library, and Ovid MEDLINE databases were screened using a Preferred Reporting Items for Systematic Reviews and Meta-Analyses-guided systematic search process. The included studies were in English, published from January 2020 to April 2024, had overall PCS prevalence as one of the outcomes studied, involved a human population with confirmed COVID-19 diagnosis and undergone assessment at 12 weeks post-COVID infection or beyond. As the primary outcome measured, the pooled prevalence of PCS was estimated from a meta-analysis of the PCS prevalence data extracted from individual studies, which was conducted via the random-effects model. This study has been registered on PROSPERO (CRD42023435280). Results: Forty eight studies met the eligibility criteria and were included in this review. 16 were accepted for meta-analysis to estimate the pooled prevalence for PCS worldwide, which was 41.79% (95% confidence interval [CI] 39.70–43.88%, I2 = 51%, p = 0.03). Based on different assessment or follow-up timepoints after acute COVID-19 infection, PCS prevalence estimated at ≥ 3rd, ≥ 6th, and ≥ 12th months timepoints were each 45.06% (95% CI: 41.25–48.87%), 41.30% (95% CI: 34.37–48.24%), and 41.32% (95% CI: 39.27–43.37%), respectively. Sex-stratified PCS prevalence was estimated at 47.23% (95% CI: 44.03–50.42%) in male and 52.77% (95% CI: 49.58–55.97%) in female. Based on continental regions, pooled PCS prevalence was estimated at 46.28% (95% CI: 39.53%-53.03%) in Europe, 46.29% (95% CI: 35.82%-56.77%) in America, 49.79% (95% CI: 30.05%-69.54%) in Asia, and 42.41% (95% CI: 0.00%-90.06%) in Australia. Conclusion: The prevalence estimates in this meta-analysis could be used in further comprehensive studies on PCS, which might enable the development of better PCS management plans to reduce the effect of PCS on population health and the related economic burden. [ABSTRACT FROM AUTHOR]

The judicial decision to overturn the federal right to abortion in the United States has profoundly influenced women across the country. Relying on 2,230 individual stories and over 500 posts on Instagram by anti-abortion activists, we investigate their discourse around abortion produced in a specific cultural moment—that of post-Roe America and a post-truth online society in which disinformation and conspiracy spread rampantly. This combined moment is particularly relevant given that people who can get pregnant are being marginalized and criminalized in American society at the same time that trust in experts and institutions is declining, thus troubling both institutional and feminist knowledge-production. Conceptually we draw on existing studies on embodied, feminist knowledge, intersectionality, populist expertise and conspiracy-believing, as well as gendered disinformation and conspiracy to show how (a) anti-abortion rhetoric devolves not only into disinformation but also conspiracy theories that are common among the alt-right and conservative online networks; (b) that the feedback loop among these communities is strong, and (c) that the anti-abortion movement on Instagram is experimenting with Gen Z rhetoric. We introduce and demonstrate the concept of embodied propaganda to capture the phenomenon of co-opting the experiences of marginalized groups in society to manipulate public opinion. [ABSTRACT FROM AUTHOR]

The article focuses on the intertwined relationship between civic integration and urban political machines in nineteenth- and early twentieth-century America, with scholars offering varying perspectives on why immigrants were mobilized by political bosses, some attributing it to a desire to instill American values while others suggest it was driven by securing electoral support through providing goods and services.

Purpose: Surgical patients with thymoma and myasthenia gravis (MG) must have their MG status and oncological outcomes critically monitored. We aimed to identify clinicopathological predictors of the postoperative MG status. Methods: We conducted a retrospective review of 40 consecutive surgical patients with MG-related thymomas between 2002 and 2020. The quantitative myasthenia gravis score (QMGS) and Myasthenia Gravis Foundation of America post-intervention status (MGFA-PIS) were used to evaluate postoperative MG status. Results: All patients underwent extended total thymectomy. The most common WHO type was type B2 (32%), while 65% of patients had type B1–B3 and 35% had type A–AB thymomas. Eleven patients (28%) achieved controlled MG status in MGFA-PIS 6 months after surgery. This controlled status was observed more frequently in type A–AB than in B1–B3 (57% vs. 12%, p = 0.007). In a multivariate analysis, WHO type (A–AB or B1–B3) was an independent predictor of worsening episodes of MG based on the QMGS (Type B1–B3, hazard ratio: 3.23, 95% confidence interval: 1.12–9.25). At the last follow-up, 23 patients (58%) achieved controlled MG status. The 5-year overall survival rate of all patients was 93.7%. Conclusion: The WHO type of thymoma is an informative predictor of postoperative MG status in patients with MG-related thymoma. [ABSTRACT FROM AUTHOR]

• Dioscorea bulbifera L. is well known for its diverse chemical composition and medicinal applications. • This systemic review covers the ethnobotany, phytochemistry, pharmacological importance and toxicity of D. bulbifera L. • Various clinical studies included in this review validate the folk usage of this herb. • The findings presented herein provide a stepping stone for future investigations into the mechanism of action of the formulations or metabolites derived from it and delve into their potential as pharmaceutical agents. Dioscorea bulbifera L. (Dioscoreaceae) is extensively being used in African, Chinese and Indian traditional medicinal systems since ages. It is an ingredient in many herbal and Ayurvedic preparations that are used against various ailments. The current study is aimed to systematically review and document findings on ethnobotany, phytochemistry, pharmacology, nutritive value and toxicity of the herb. The study is intended to overcome the inconsistency between the traditional and pharmacological applications of the herb concerning its folkloric use and offer novel insights for future researchers. The literature was systematically collected from various offline and online sources using relevant keywords. Electronic databases including Google Scholar, PubMed, Science Direct, Springer Online, Research Gate, Scopus etc. were used to retrieve the relevant information. D. bulbifera L. is widespread in tropical and temperate regions of Asia, Africa and America. In traditional medicinal systems, it is used widely to cure sore throat, skin diseases, ulcers, boils, piles, pain, inflammation, dog bites, snake bites, food poisoning, asthma, cough, tuberculosis, cold, jaundice, malaria, typhoid of children, contraceptives, diabetes, ophthalmia, pink eye conjunctivitis etc. Among bioactive constituents, aglycone types of steroidal saponins dioscorin(e), dioscin(e), diosbulbin, and diosgenin possess significant biological activities. The chemical structures of the phytoconstituents presented in this review are drawn using ChemDraw Ultra software. The clinical studies included in this review have been performed to validate the folk usage of this herb. However, more studies are required to be done on scientific and clinical aspects to support its therapeutic applications. The updated information provided in this systematic review would open new perspectives for performing in-depth analysis of pharmacological research in future. The study would be useful for improving the clinical use of the herb and is surely going to bridge a gap between the traditional and modern use of scientific research for future researchers. [ABSTRACT FROM AUTHOR]

The Moon Village Association Italian associates and institutional partners successfully organized a remarkable Space Summer School in Italy on July 24th and 25th, 2023. This event coincided with the celebration of International Moon Day 2023. The school was conducted in a hybrid mode, blending in- person and virtual participation, making it accessible to a wide audience. With an overwhelming response, more than 70 individuals registered for the event, showcasing the significant interest and enthusiasm among stakeholders from various backgrounds. The school provided an unparalleled networking experience, bringing together speakers and attendees from over ten (10) different countries across Europe, Asia, America, and Africa As an NGO, the MVA’s primary objective is to establish a permanent global forum for governments, industry, academia, and the public invested in lunar exploration. With over 600 participants, the MVA embodies a wide spectrum of technical, scientific, cultural, and interdisciplinary fields. The IMD is an annual event celebrated worldwide to raise awareness about the status and future prospects of sustainable Moon exploration and utilization. The experience of organizing and leading the school event, along with the participants’ follow up three months after the school, will be documented in this essay. This documentation seeks to illustrate the school’s role in addressing global societal issues and understanding the significance of such activities in tackling challenges related to the Moon and beyond. Overall, the school proved to be a resounding success, leaving a lasting impact on the international lunar exploration community, and nurturing a collective vision for humanity’s future in space. [ABSTRACT FROM AUTHOR]

We are witnessing a new space race. In the past few years, the number of successful launches to low Earth orbit has been higher than at any time since Sputnik. Commercial space companies, led by SpaceX and Blue Origin, have developed reusable rockets that are fundamentally changing the economics of spaceflight and opening new markets for recreation and tourism. Large numbers of small satellites are being deployed to monitor Earth resources and deliver high speed Internet to developing countries. Meanwhile, a growing number of countries have built space programs, and a superpower rivalry between China and America has replaced the traditional competition between Russia and America. All this activity raises legal and ethical issues. Space debris is accumulating at a rapid rate, creating a hazard for humans and hardware in low Earth orbit. Currently, there is no real incentive for companies or governments to mitigate this threat. The ownership of space resources is not covered by international law and in most countries, spaceflight is subject to very little regulation. Another concern is the potential militarization of space by the major powers. As we explore space, exploitation may be taking precedence over conservation. Hopefully, the economic benefits of space will be realized while the activity grows ethically and sustainably. [ABSTRACT FROM AUTHOR]

This study evaluated the efficacy and safety of eculizumab, a terminal complement C5 inhibitor, in juvenile generalized myasthenia gravis (gMG). Adolescents aged 12 to 17 years with refractory anti-acetylcholine receptor (AChR) antibody-positive gMG received eculizumab (weekly induction [one to two doses of 600 mg or four doses of 900 mg] followed by maintenance doses [300 to 1200 mg] every two weeks for up to 26 weeks) in a phase 3, open-label multicenter study (NCT03759366). Change from baseline to week 26 in Quantitative Myasthenia Gravis (QMG) total score (primary end point) and secondary end points including Myasthenia Gravis-Activities of Daily Living (MG-ADL) total score, Myasthenia Gravis Composite score, Myasthenia Gravis Foundation of America postintervention status, EuroQol 5-Dimensions (Youth) and Neurological Quality-of-Life Pediatric Fatigue questionnaire scores, as well as pharmacokinetics, pharmacodynamics, and safety, were recorded. Eleven adolescents (mean ± S.D. age 14.8 ± 1.8 years) were enrolled; 10 completed the primary evaluation period. Least-squares mean changes from baseline at week 26 were −5.8 (standard error [SE] 1.2; P = 0.0004) for QMG total score and −2.3 (SE 0.6; P = 0.0017) for MG-ADL total score. Overall, the primary and all secondary efficacy end point analyses met statistical significance from the first assessment and were sustained throughout. Complete terminal complement inhibition was sustained through 26 weeks in all patients. Treatment-emergent adverse events were all mild/moderate and predominantly unrelated to eculizumab. Eculizumab was effective in reducing disease burden and was well tolerated in adolescents with refractory AChR antibody-positive gMG. [ABSTRACT FROM AUTHOR]

In this article, we elaborate on the central themes of our recent book, The New Nationalism in America and Beyond (OUP, 2022), before responding to the comments and criticisms of several esteemed colleagues (Phil Gorski, Cynthia Miller‐Idriss, and Sophie Duchesne). In sum, our book argues that the relative success of right‐wing populists among the white majorities of the West – including Donald Trump in the US, Marine Le Pen in France, and the Brexit Campaigners in the UK – is partly due to the way in which they draw upon long‐established ethnic nationalist myths and symbols in their political communication. By adapting this cultural content to the contemporary context, these elites are ensuring that their messaging resonates among their target populations. In making this case, our book seeks to demonstrate the value of taking culture seriously in the analysis of the so‐called 'new nationalism.' [ABSTRACT FROM AUTHOR]

Background and purpose: This study was undertaken to highlight neonatal Fc receptor inhibition (efgartigimod) as a valuable therapeutic option for patients with refractory seronegative myasthenia gravis (MG) and to emphasize the concept that seronegative MG is greatly constrained by the limitations of currently available diagnostic methods and therapeutic measures. Methods: We describe the first refractory, generalized MG (gMG) patient successfully treated with efgartigimod after testing negative on standard autoantibody detection tests. Results: Our patient presented with severe fluctuating bulbar and generalized weakness, resulting in multiple myasthenic crises requiring intubation. After a 28‐year medical history of multiple failed lines of treatment, our patient was started on efgartigimod. Over five treatment cycles, a definite improvement in her clinical condition was observed (Myasthenia Gravis Foundation of America class: IIIb to IIb; MG‐Activities of Daily Living score: 11 to 0; MG‐Quality of Life 15 score: 30 to 0; Quantitative MG score: 28 to 6). Standard autoantibody detection tests failed to detect known pathogenic autoantibodies, but cell‐based assay (CBA) identified autoantibodies against clustered adult acetylcholine receptor (AChR). Conclusions: In light of recent approvals of efgartigimod by the European Medicines Agency and US Food and Drug Administration exclusively for AChR‐positive gMG forms, our case highlights evidence suggesting that such an approach might be shortsighted and could limit therapeutic options for patients with refractory seronegative gMG. Additionally, introducing more sensitive analytical techniques, exemplified by CBA, may help bridge the gap between seronegative and seropositive patients. This represents an urgent unmet need for gMG patients, as the antibody profile dramatically influences the therapeutic approach. [ABSTRACT FROM AUTHOR]

Nearly 20 years have passed since this journal's last review of Latino politics. Today, American politics have shifted dramatically, even alarmingly, with Latinos absorbing and contributing to many of these changes. Yet American politics research still overwhelmingly privileges non-Hispanic Whites and their political opinions and behavior. We argue that this marginalization of Latino politics research has even fewer excuses in this era when data, methodologies, and other resources have expanded, making theory-based, empirically grounded research on Latino politics more feasible. We also argue that to better grasp what happens in contemporary politics today and tomorrow, a deeper understanding of Latinos' political psychology is indispensable because they are a highly diverse, minoritized group whose members are acutely sensitive to structural, temporal, and situational pressures. Finally, in an overwhelmingly quantitative, empirically oriented field, we urge Latino politics scholars to more earnestly consider the normative implications of research on this growing pan-ethnic population. [ABSTRACT FROM AUTHOR]

Drawing on Jean Baudrillard's theorizing of the theme park, this study recognizes the TV show Westworld (2016-2022) as a simulation of contemporary America with intriguing questions about rape culture and justice in a post-#MeToo moment? In seasons 1 and 2, android characters like Dolores (Evan Rachael Wood), Maeve (Thandiwe Newton), and Akecheta (Zahn McClarnon) are violated but rebel against sexist and racist programing, and the "Man in Black" represents the violating nature of the stereotypical, Western hero. The principles of the Old West, like benevolent violence, are reflected in a TV industry where the actors of Westworld document their own violation in #MeToo artifacts, such Wood's documenting of abuse in Phoenix Rising (2022), and interviews with Newton. In thinking about justice, Westworld falters, because it frames redress only in terms of further violence and revenge. Wood and Newton, however, represent the prevention of future violence, offering a possibility of justice. [ABSTRACT FROM AUTHOR]

Objectives: Describe the characteristics of the different cardiology medical residencies in Latin America. Method: Cross-sectional study that aims to evaluate the characteristics of cardiology residencies in Spanish-speaking countries of Latin America, through self-administered electronic surveys. Results: Three hundred seven residents of 147 residences were surveyed. Mean age was 31 years and 63% were male. Ninety eight percent carry out their training in the capital city. The average total training time is 4.8 years. Forty four percent complete their residency in internal medicine prior to starting cardiology, and 10% have no prior training. In cardiology training is 3 years in most countries. Fifty four percent present academic activities every day and 16% only once or less, consisting of theoretical classes (93%), clinical cases (85%), bibliographic workshops (69%), and writing scientific papers (68%). Supervision is carried out by the chief resident (45%), resident coordinator (44%), resident instructor (27%) or the department head (54%), while 2.6% do not present supervision. The main rotations were echocardiography (99%), hemodynamics (96%), coronary unit (93%), and electrophysiology (92%). Residents highlighted the need to improve academic activities (23%) and scientific production (12%). Conclusions: There are important differences in the academic and practical training between the residences of the different countries of America. [ABSTRACT FROM AUTHOR]

By way of autoethnographic poetry, I reflect on my personal struggles related to racial consciousness as I embarked on a journey—from America, across the Atlantic, and eventually, to the Indian Ocean off the East Coast of (mother) Africa. The story of my apparent racial crisis is viewed through multiple lenses, as I infuse the pivotal readings of The Black Atlantic, Lose Your Mother, The Collected Poems of Langston Hughes, and personal experiences both in autoethnographic and in poetic form. [ABSTRACT FROM AUTHOR]

Social Impact Statement: The genetic variation of crop wild relatives will be key for our survival, as environmental change represents an increasing global threat for agriculture and food security. Cucurbita lundelliana and Cucurbita okeechobeensis subsp. martinezii are wild relatives of cultivated squashes and pumpkins that could be used for crop improvement. A genomic approach was used to characterize genetic resources in these taxa, that is, to identify candidate sites in the genome involved in responses to abiotic stress, and to understand the roles of gene flow and environmental differentiation in their divergence. This study highlights the importance of conserving these two species as phytogenetic resources for crop improvement. Summary: Crop wild relatives (CWR) are reservoirs of genetic diversity and they are important for the maintenance of crop evolutionary potential. Mexico is the centre of domestication and diversity for many CWR. The genus Cucurbita originated in America, where at least six independent domestication events took place. Nonetheless, Cucurbita CWR have been seldom studied. In the present study, we test the role of incomplete lineage sorting (ILS) and secondary contact in the divergence of C. okeechobeensis subsp. martinezii and C. lundelliana. Additionally, we seek to understand the role of environmental differentiation in their divergence.We obtained 1,638 single nucleotide polymorphisms (SNPs) for 107 individuals from the most recently diverged wild species in this genus, encompassing 25 localities of C. lundelliana and nine localities of C. okeechobeensis subsp. martinezii in Mexico.We found higher genetic variation in C. lundelliana (HE = 0.227) than in C. okeechobeensis subsp. martinezii (HE = 0.187). Each taxon constitutes a well‐differentiated genetic group, with an area of introgression in Pantanos de Centla. We found candidate loci associated to hydric and thermal stress, which could be valuable for crop improvement. Our study supported a scenario of ILS followed by secondary contact, where divergence was probably driven by Pleistocene climate change.These CWR represent important phytogenetic resources for crop improvement given their high levels of genetic variation and differentiation and their SNPs associated to different climatic variables. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Ciencias Sociales (13159518) is the property of Revista de Ciencias Sociales de la Universidad del Zulia Venezuela and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Araucaria is the property of Araucaria-Revista Iberoamericana de Filosofia, Politica y Humanidades and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article discusses the history of the perception of sugar from antiquity to the Middle Ages. The author shows how changes in society can be demonstrated by changes in the reflection of dietary attitudes towards sweet taste. Medieval society was influenced by ambiguous attitudes towards sugar and sweets in general. On one hand, sweet taste was associated with the risk of mental malaise, which contradicted religious devotion to the Christian faith; on the other hand, the description of sweet taste was often used symbolically in the Bible as an allegory of reward for strong faith. Sugar, however, found its way into pharmacy as a medicine and, above all, as a sweetener. Medieval trade between Europe and its Arab neighbours and the development of urban and international trade eventually opened the way for sugar cane to enter Europe. European merchants learned to produce sugar and, from the 16th century onwards, took their technological knowledge or knowledge of the organisation of cane sugar production to the newly discovered territories in America. The transfer of knowledge was the precursor to the Industrial Revolution and medieval concepts of sugar were forgotten. This article therefore provides a brief overview of medieval mindset regarding sugar and sweet taste. [ABSTRACT FROM AUTHOR]

In Irish tradition it was believed that both the living and the dead might in certain circumstances appear at a distance from their bodies. This article considers occasions where such supernatural visitations happened close to the moment of the death. Deathbed apparitions or 'crisis apparitions' were reported widely in Europe and America, but have not been much explored by historians. In crisis apparition stories, the dying or just-dead person visited a neighbour, friend or close relative and a key feature was that the percipient would declare what they had seen, even before confirmation had arrived of the death. Accounts dating from between about the 1820s and 1940s provide the basis for an exploration of the crisis apparition both as reported in Ireland and among Irish people abroad. That many crisis apparitions communicated across the Atlantic reflects the anxieties of 'exiles' and their friends and families about death far from home, and this article also considers their role in bridging gaps in conventional communications. Accounts of supernatural leave-taking also travelled across time, offering insights about how storytelling assisted the processing of grief and the handing down of the dead over generations that are relevant to other contexts far beyond Ireland's shores. [ABSTRACT FROM AUTHOR]

Introduction: The Colorado potato beetle (Leptinotarsa decemlineata) (CPB) is a major threat to potato crops in Europe, Asia, and America. In Europe, it is expected that climate change will cause the species to expand its range northwards and allow for an additional generation per year in regions where it is already established. The effectiveness of insecticides, a common method of control, is decreasing due to the emergence of resistance to several substances. Therefore, research into alternative measures is becoming increasingly necessary. One preventive measure that has already been shown to have great effects in past studies is the use of organic mulch. For organic mulching, conserved or freshly cut plant material is spread on the field usually when the potato emerges. Previous research has mainly used cereal straw for this purpose in plots that are relatively small compared to actual agricultural fields. Materials and methods: To address the lack of large-scale field trials in the literature, a series of on-station and on-farm field trials were conducted in this study. Organic, legume-rich mulches were used primarily, which so far have not been extensively investigated. Over a period of four years and in a total of six field trials, CPB and larval infestations were assessed. Results and discussion: Our results show effects on the initial infestation of young plants by adult CPB and on the emergence time of the first two larval stages. By the time of flowering, when the feeding effect of CPB on yield is known to be greatest, L3 and L4 larvae were reduced by about 30% in the on-station trials and by about 40% in the on-farm trials. In addition, when CPB larval stages were used to calculate a weighted daily leaf consumption per stage, total calculated leaf consumption was on average about 40% lower in the mulch treatments across all sampling dates and all trials. The recorded yields were equal or higher in the mulched treatments. In conclusion, organic mulching can effectively reduce CPB damage even on a large scale and can have a positive impact on yield. Further agronomic benefits of mulching, as well as drawbacks and putative mechanisms of action, are discussed. [ABSTRACT FROM AUTHOR]

We used the quantile vector autoregressive (QVAR) dynamic connectedness framework to examine whether leading stock markets in America and Europe would have any impact on major stock markets in Asia.1 More precisely, we analyzed systematically the stock market connectedness in 15 countries, namely Germany, the UK, the USA, and 12 Asian countries, which include five major ASEAN countries, namely Indonesia, Malaysia, Philippines, Singapore, and Thailand from 1996 to 2023. The findings indicated that Hong Kong and Singaporean stocks were major transmitters of financial shocks at the extreme low price market condition, while Germany and UK were minor transmitters. By contrast, the USA could be considered the major transmitter of financial shock during the extreme high market price returns condition. In the normal market condition, these three countries in Europe and America are important transmitters of financial shock. More interestingly, the empirical findings indicated the centrality of Singapore in the stock market connectedness in Asia. 1 The authors are grateful to Professor David Gabauer who makes available the R codes for all calculations in this paper. [ABSTRACT FROM AUTHOR]

In early twentieth-century America, ownership of all four Shakespeare folios was a benchmark for rare-book collectors, showcasing a dedication to assembling an exceptional library. The First Folio (1623) typically commanded the highest prices. Dealers sought to capitalize on the popularity of Shakespeare's works by labelling a wide range of material as 'Shakespeareana', and the 1920s saw a boom in the market for early English plays. For some American collectors, notably Henry Folger, one copy of an edition was not enough, but others, including Henry Huntington, released duplicates back into the market, helping to keep interest high and facilitating the use of books as investments in the 1920s. This article examines the transatlantic trade in early English drama from c.1900 to 1929, to situate sales of First Folios in their economic and cultural context and to explore why large numbers of sixteenth-century English plays are now held in a handful of American libraries. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of the L.N. Gumilyov Eurasian National University. Philology Series is the property of L.N. Gumilyov Eurasian National University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The US Indo-Pacific Command (USINDOPACOM) is tasked with deterring and preparing for a potential conflict with China, while also facing a clear threat from North Korea (DPRK) against the American Pacific homeland. To address mounting cooperation among adversaries, the US should establish a designated homeland defense operation, enabling USINDOPACOM to activate Joint Task Force-Homeland Defense, augment its forces with Reserve component units, and enhance regional defense capabilities. These measures would mitigate risk in a China scenario and reaffirm US sovereignty in the Pacific. With further DPRK missile and nuclear tests expected, launching this operation would be a proportionate response. The Secretary of Defense must now direct planning for Operation Noble Eagle-Pacific. [ABSTRACT FROM AUTHOR]

Copyright of Trashumante. Revista Americana de Historia Social is the property of Universidad de Antioquia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Trashumante. Revista Americana de Historia Social is the property of Universidad de Antioquia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This article reads the seminal text-based computer videogame Colossal Cave Adventure (1976–77) as a key document to understand videogame and computing history's fraught relationship with race. It situates its simulation of underground exploration in the context of the actual location that inspired it: Kentucky's Mammoth Cave system, a destination that was immensely popular with tourists in the mid-nineteenth century, but also relied heavily on the labor of enslaved Black men. This article examines what it means for one of the foundational videogame texts to be modelled after a space historically marked by Black slave labor; it positions Adventure and the programming culture from which it emerged, and in which it was so enthusiastically received, as crucial sites to understand how the ideology of whiteness as an unraced, universal position came to be so enmeshed with videogame and computer culture. The ramifications of Adventure 's relation to race are explored through a reading of Cardboard Computer's critically acclaimed videogame Kentucky Route Zero (2012–2020), which pays homage to Adventure by using the Mammoth Cave as a setting for its magical realist exploration of the entanglement of media history, labor, and dispossession in America, but ends up providing a whitewashed account of the labor that shaped the region. [ABSTRACT FROM AUTHOR]

Copyright of Pasado y Memoria. Revista de Historia Contemporánea is the property of Pasado y Memoria and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

With the rapid developm the application of digital ent of the new generation of information and communication technologies (ICT), the state-level governance model has undergone profound changes. It is worth pondering whether this change will have an impact on the carbon peak and carbon neutrality goals. Therefore, we collected data from 51 global economies that have proposed carbon neutrality targets from 2003 to 2020 to build a series of spatial measurement models and explored the impact of e-government construction on carbon emission intensity (CEI). Then, we further considered regional heterogeneity factors, grouped the selected countries into Asian, European, and American countries, and verified the differences between e-government construction and CEI in different regions. Additionally, on the basis of the spatial mediation effect model, this paper analyzed the industrial structure which played an intermediary role in achieving target for reducing CEI through e-government construction. The main findings are as follows. (1) A higher level of e-government construction will result in lower-carbon emissions intensity. (2) Spatial spillover effect regression results showed that the construction of e-government in neighboring countries also significantly inhibits the carbon emission intensity of the host country. (3) There was significant regional heterogeneity in the impact of e-governments on CEI; in Asia, the construction of e-governments significantly reduced CEI, but no significant reductions were observed in Europe and America. (4) E-governments influenced CEI by optimizing the industrial structure. The construction of e-governments was effective in Asia and Europe, while intermediary effect test was failed to pass in the Americas. This study mainly focused on the environmental benefits brought by the construction of e-governments, and the obtained results would provide an important reference for the achievement of the dual-carbon goals in countries worldwide. [ABSTRACT FROM AUTHOR]

Working with data about homicide victims and perpetrators from 50 of America's largest cities, we investigate the explanatory power of some familiar explanations for why murder in those cities rose sharply in 2020. The analysis reveals that the distribution of risk by race was essentially the same in 2020 as in 2019. That empirical finding challenges some theories of how racial tensions after the death of George Floyd may have driven homicide increases. Similarly, homicide growth was not concentrated in those cities with the greatest availability in 2020 of new and older guns, or among the cities that suffered the most from the COVID‐19 pandemic. At a minimum, the cross‐city outcomes should reduce confidence that some combination of "race, guns, and COVID‐19" explains all of the most important aspects of what happened in 2020. [ABSTRACT FROM AUTHOR]

The author is a trained book conservator and frequently gives free book repair workshops to local public and school librarians. This study was a nationwide survey of American school librarians to inform future workshops. Participants were asked about the damage they found to library books and whether those damaged books were weeded, repaired, or left as-is. They were then asked to describe how they carried out specific repairs. The author added suggestions to supplement the repair techniques participants discussed. The author concludes that most damage from school library books can and should be treated in-house, which is preferable to discarding. [ABSTRACT FROM AUTHOR]

Summary: What can the historical study of early American legations in Europe tell us about how the United States approaches its embassies in the world today? Embassy buildings today represent over two hundred years of American trial and error in constantly shifting foreign political environments. They are, by their nature, intended to straddle multiple modalities: public and private; political and personal; global and local. It was because of their deliberately fluid representational states that the first American diplomatic missions to Europe could attempt to bridge the paradigm of aristocratic and democratic approaches to embassy curation abroad. As the first modern post-colonial democracy, the diplomatic agents of the US experimented with the placement, decoration and occupation of their ministerial spaces. In doing so, they innovated strategies of fluidity still seen in American embassies today. [ABSTRACT FROM AUTHOR]

AbstractThis article invites middle and high school social studies teachers and students to address the question, “Is the United States Exceptional?” We define American exceptionalism as the belief that the United States is qualitatively different from other nations based upon having some special virtue, ideology, or mission that makes it an outlier. We identify four themes or components of American exceptionalism: democracy, individual liberty, opportunity, optimism. We then call for letting students decide for themselves whether, when, and how the United States has been an exceptional nation while studying U.S. and world history. We close considering the advantages of allowing students to explore America as an exceptional nation in the current moment. Inquiring into American exceptionalism positions students studying U.S. and world history to construct their own nuanced understandings, to see from multiple perspectives, and to consider the United States in a global context. [ABSTRACT FROM AUTHOR]

AbstractThe social movements of the last few years have highlighted the continued institutional inequities that exist in the United States. They have reinvigorated policy and administrative practices and programs that support DEIJ. They have also reawakened in earnest a battle that has been waged since colonial America, one in which people in power work to pass policies and promote institutions that undo social equity and uphold oppression. As public administration scholars and teachers, it is critical for us to give our students the tools, language, and skills necessary to fight against oppression. In this dialogue, I present advice from social equity scholars on how to accomplish this by highlighting conversations from a roundtable discussion held at PATNet 2023. Themes include overall feelings about teaching social equity, discussing positionality, incorporating interdisciplinary theory, linking theory to practice, and teaching under censorship. [ABSTRACT FROM AUTHOR]

Purpose: Physical inactivity and sedentary behaviors are key contributors to the rising rates of childhood obesity. Though many adolescents are aware of the benefits of exercise, youth in America are not sufficiently active. This study examined changes in physical activity (PA), physical education (PE), and sedentary behaviors among Black adolescents. Methods: Pooled data from Black high school students (n = 2,233) who completed the Youth Risk Behavior Survey (YRBS) from 2009–2019 in Broward County, Florida, were analyzed. Logistic and linear regression models examined trends in selected physical activity indicators. Results: There were no significant changes in recommended physical activity levels (p = .829), daily physical activity (p = .44), PE class attendance (p = .054), or the average number of days of PA engagement (p = .304) for this time period. However, there was a significant decline in daily PE class attendance, the average number of days of PE attendance, and excessive television watching (p < .001). There were also increases in excessive video gaming and computer usage (p = .002). Conclusion: Adolescents’ physical activity behaviors have not declined substantially over the past decade. However, sedentary behaviors, such as computer use and video gaming, have markedly increased. Results presented here should assist in broadening the understanding of Black adolescents’ views on weight and physical activity and developing local programs and interventions to promote regular physical activity aimed at this population. [ABSTRACT FROM AUTHOR]

There are worldwide growing concerns about environmental issues such as global warming and climate change. Moreover, it is expected that there will be regional differences in environmental issues. Therefore, this study focuses on a tri-regional comparison: America, Europe, and Asia-Pacific. Previous literature has paid less attention to exploring regional comparisons while considering regional heterogeneity. Against this backdrop, this study delves into the dynamic relationship between fossil fuel utilization, economic growth, globalization, urbanization, and CO2 emissions to understand the environmental implications of these interconnected factors. The study period spans from 1990 to 2021. Additionally, it employed rigorous tests to confirm cross-sectional dependence and data heterogeneity, following methodologies proposed by Pesaran (2004, 2015) and Pesaran (2007), utilizing the CS-ARDL panel cointegration methodology by Chudik and Pesaran (2015). The results confirm long-term significant relationships among OC, NGC, FDI, and UR variables in both combined panels, with and without regional dummies. However, GDP and COC become insignificant in the long run in the dummy variables regression. Furthermore, the regional dummies were found to be negative but remain insignificant, possibly due to heterogeneous effects or unobserved factors influencing each region independently. Analysis by region reveals predominant coal consumption in Asia, higher oil consumption in America, and greater gas consumption in Europe. Economic growth and CO2 emissions are positive in Asia and America but negative in Europe, aligning with theories prioritizing growth over environmental concerns in Asia and America, and advocating for renewable energy adoption in Europe. Urbanization increases energy demand and emissions, supporting the environmental revolution theory, while FDI holds the potential to reduce CO2 emissions, as per the endogenous growth theory. [ABSTRACT FROM AUTHOR]

Mona Lisa Smile (2003) and Dead Poets Society (1989) are two American films that made audiences across the globe reflect their learning paradigms. A rhizomatic educational ambiance helps to transform students from a state of stasis into dynamic individuals as it deterritorializes them from indoctrination by arborescent principles put forth by the ideological apparatuses of family, educational, and cultural institutions to an individual space where they can define themselves. This research paper attempts to look at Mona Lisa Smile and Dead Poets Society as visual texts that attempted to comment upon the rigidities that existed in America during the 'Fifties'. The conclusion provides a comparison of the learning outcomes in the two sets of learners in the films selected and describes the reasons why students in Mona Lisa Smile metamorphosize into dynamic individuals committed to a definite career path. [ABSTRACT FROM AUTHOR]