Search

Your search keyword '"Alfaro-Acha A"' showing total 74 results
Start Over Author "Alfaro-Acha A"
74 results on '"Alfaro-Acha A"'

52. The force-velocity relationship in older people

Author

Alcázar Caminero, Julián, Rodríguez López, Carlos, Ara Royo, Ignacio, Alfaro Acha, Ana, Mañas Bote, Asier, Guadalupe Grau, Amelia, García García, Francisco José, and Alegre Durán, Luís María

Subjects
Aging, Muscle function, Muscle power, Functional ability, Power training, Resistance training
Abstract

This study compared the reliability and validity of different protocols evaluating the force-velocity (F-V) relationship and muscle power in older adults. Thirty-one older men and women (75.8 ± 4.7 years) underwent two F-V tests by collecting the mean and peak force and velocity data exerted against increasing loads until one repetition maximum (1RM) was achieved in the leg press exercise. Two attempts per load were performed, with a third attempt when F-V points deviated from the linear F-V regression equation. Then, the subjects performed 2 × 3 repetitions at 60 % 1RM to compare purely concentric and eccentric- concentric repetitions. The Short Physical Performance Battery was conducted to assess the validity of the different protocols. Significant differences were found in maximal power (Pmax) between mean and peak values and between protocols differing in the number of attempts per load (p < 0.01). Registering mean values, a third attempt, and multiple loads (>3), was significantly more reliable (Pmax: CV = 2.6 %; ICC = 0.99) than the other alternatives. Mean values were also observed to be more associated with physical function than peak values (R2 = 0.34 and 0.15, respectively; p < 0.05). No significant differences were observed between concentric and eccentric-concentric repetitions. Thus, collecting mean force and velocity values against multiple loads, while monitoring the linearity of the F-V relationship, seemed to be the more adequate procedure to assess the F-V profile and muscle power in older adults.

Published
2017

53. Endocrinology of Aging From a Muscle Function Point of View: Results From the Toledo Study for Healthy Aging

Author

Jose Losa-Reyna, Ana Alfaro-Acha, Leocadio Rodríguez-Mañas, José A. Carnicero, Francisco José García-García, Carmen Castillo, Maria Carmen Gomez-Cabrera, Jesús A.F. Tresguerres, Cristina Rosado-Artalejo, and Amelia Guadalupe-Grau

Subjects
0301 basic medicine, Male, medicine.medical_specialty, Anabolism, medicine.medical_treatment, Dehydroepiandrosterone, Endocrine System, Isometric exercise, Physical strength, Logistic regression, Healthy Aging, 03 medical and health sciences, chemistry.chemical_compound, Insulin-like growth factor, 0302 clinical medicine, Dehydroepiandrosterone sulfate, Internal medicine, medicine, Humans, 030212 general & internal medicine, Muscle Strength, Muscle, Skeletal, General Nursing, Aged, business.industry, Health Policy, Mortality rate, General Medicine, Hospitalization, 030104 developmental biology, Endocrinology, chemistry, Spain, Female, Geriatrics and Gerontology, business
Abstract

Aging is a process that involves a reduction in muscle strength and anabolic hormone concentrations, which impacts significantly on health.To study the hormone/total strength (H/TS) ratio as a proxy of anabolic insensitivity status in elders, and its relationship with disability, hospitalization, and mortality risk.A total of 1462 persons aged ≥65 years from the Toledo Study of Healthy Aging participated in this study. Serum concentrations of insulin like growth factor 1, total and free testosterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate, and 17β-estradiol were measured. Total maximal voluntary isometric strength was obtained (handgrip, shoulder, hip, and knee) using standardized techniques and equipment. Physical activity was recorded by physical activity scale for the elderly questionnaire. Associations of the H/TS ratio with hospitalization and mortality were assessed using logistic regression models, and participants stratified into quartiles for each H/TS ratio.In women, all individual ratio H/TS models showed a strong to moderate increased risk for death and hospitalization. In men, all models revealed a significant positive association of the ratio H/TS with mortality rate but not for hospitalization (P .01). Participants who have 2 or more H/TS ratios in the worst quartile increased the risk of hospitalization and mortality at least by 2-fold.We demonstrate the main role that muscle function plays in the relationship between the hormonal status and hospitalization and mortality risk; this could be taken into consideration as a way to classify patients for hormonal therapy.

Published
2016

55. Colaboradores

Author

Abizanda Soler, Pedro, Agudo Mena, José Luis, Aguilar, Adriana B., Alarcón Alarcón, Teresa, Albrecht Junghanns, Rodolfo Emmanuel, Alfaro Acha, Ana, Almaida Pagán, Pedro Francisco, Alonso Bouzón, Cristina, Alonso Fernández, Teresa, Alvira Rasal, Berta, Andradas Aragonés, Elena, Andrés Lacueva, Cristina, Angulo Frutos, Javier, Arche Coto, José Miguel, Ariza Zafra, Gabriel, Arriola Manchola, Enrique, Avellana Zaragoza, Juan Antonio, Avendaño Céspedes, Almudena, Defez, José Manuel Azaña, Elías, Íñigo Azcoitia, Balducci, Lodovico, Bardales Mas, Yadira, Baztán Cortés, Juan José, Varea, Ángel Belenguer, Bermeo Serrato, Sandra Milena, Menéndez de la Granda, Manuel Bermúdez, Borrás Blasco, Consuelo, Burcet Pérez, Silvia, Mora, María Ángeles Caballero, Cabré Roure, Mateu, Calcaterra, Laura, Camilo Beltrán, Jonathan, Cano Gutiérrez, Carlos Alberto, Casas Agustench, Patricia, Herrero, Álvaro Casas, Castro Rodríguez, Marta, Cebollero Ribas, Pilar, Celaya Cifuentes, Sara, Cesari, Matteo, Chavarro Carvajal, Diego Andrés, Chaves, Paulo H.M., Chodzko-Zajko, Wojtek, Clavé Civit, Pere, Contreras Escámez, Beatriz, Contreras Luque, Claudia Patricia, Santiago, Dámaso Crespo, Allue, Ramón Cristófol, Cristofori, Giovanna, María Cuervo, Ana, Cuesta Triana, Federico, Curcio Borrero, Carmen Lucía, de Costa Ruiz, Jorge, Rey, Mónica de la Fuente del, de la Fuente Gutiérrez, Carlos, Martín, María de la Puente, del Pozo Guerrero (D.E.P.), Francisco, Domínguez Martín, Laura, Duque Naranjo, Gustavo, Durio Calero, Enrique Antonio, Enfedaque Montes, Belén, Escobar Gómez, Lina María, Esquinas Requena, José Luis, Esteve Arríen, Ainhoa, Estrella Cazalla, Juan de Dios, Fernández, Agustín F., Fernández, Iñaki Fernández de Trocóniz, Fernández Fernández, María, Fernández Martínez, Nuria, Fernández Minaya, Dionis Carolina, Fernández Rodríguez, Esperanza, Fernández Viadero, Carlos, Flores Ruano, Teresa, Fraga, Mario F., Galmés Belmonte, Ignacio, Gambini Buchón, Juan, Garatachea Vallejo, Nuria, Garcia Cifuentes, Elkin, García Esquinas, Esther, García García, Francisco José, García Navarro, José Augusto, García Sánchez, Sergio, García Segura, Luis Miguel, Garreta Buriel, Marisa, Garrido Cid, María Jesús, Gil Gregorio, Pedro, Gimeno Mallench, Lucía, Gómez Fernández, Marisol, Gómez Montes, Fernando, Gómez Pavón, Javier, González-Colaço Harmand, Magali, González García, Paloma, González Guerrero, José Luis, González Montalvo, Juan Ignacio, Gramunt Fombuena, Nina, Grande Martín, Alberto, Guerrero Díaz, María Teresa, Luis Guerrero Solano, José, Gutiérrez Robledo, Luis Miguel, Gutiérrez Rodríguez, José, Hendry, Anne, Heras Benito, Manuel, Hernández Zamora, Paulo, Hernández Zegarra, Pablo Alberto, Hoogendijk, Emiel O., Hornillos Calvo, Mercedes, Huedo Rodenas, Isabel, Pérez de Heredia, Javier Hueto, Ibarzábal Aramberri, Xabier, Inzitari, Marco, Izquierdo Redín, Mikel, Jiménez Muela, Francisco, Jiménez Rojas, Concepción, Jiménez Segura, José Daniel, Jordán Bueso, Joaquín, Jové Font, Mariona, Júdez Navarro, Enrique, Juncos Martínez, Gema, Laosa Zafra, Olga, León Ortiz, Matilde, Limón Ramírez, Esther, Linge Martín, Magdalena, Arrieta, Jesús María López, Chicharro, José Luis López, López-Dóriga Bonnardeaux, Pedro, López García, Esther, López Jiménez, Esther, Sáez de Asteasu, Mikel López, López Utiel, Melisa, Lozano Berrio, Vicente, Lozano Montoya, Isabel, Lucía Mulas, Alejandro, Luengo Márquez, Carmen, Madrid Pérez, Juan Antonio, Manzarbeitia Arambarri, Jorge, Fuentes, Ángel Martín, Martín Martínez, Alberto, Martín Sanz, Eduardo, Sebastiá, Asunción Martín, Martín Sebastiá, Elena, Luz Martínez, Iveris, Martínez Antón, Miguel Ángel, Montandón, Álvaro Martínez, Martínez Ramírez, Alicia, Martínez Reig, Marta, Velilla, Nicolás Martínez, Mas Bergas, Miquel Àngel, Mas Romero, Marta, Matheu, Ander, Mazoteras Muñoz, Virginia, Miguel Alhambra, Luciana, Millor Muruzábal, Nora, Basseda, Ramón Miralles, Mohedano Molano, Julia, Garrido, María José Molina, Molina Olivas, Marta, Guix, José Luis Molinuevo, Montero Moreno, Javier Antonio, Montero-Odasso, Manuel, Morales Martínez, Fernando, Moreno Cugnon, Leire, Moreno Valladares, Manuel, Mosquera Gorostidi, Carmen, Negrín Mena, Natalia, Noguerón García, Alicia, Ochando Ibernón, Gemma, Olaso González, Gloria, Oliva Moreno, Juan, Carbonell, José Luis Oliver, Ortega Fernández, Omar, Pamplona Gras, Reinald, Fernández, José Manuel Pardal, Pareja Galeano, Helios, Pareja Sierra, Teresa, García, José Francisco Parodi, Pedraza Sepúlveda, Laura, Peláez, Martha B., Peña Longobardo, Luz María, Pérez Bazán, Laura Mónica, Pérez-Jara Carrera, Javier, Pérez Rodríguez, Rodrigo, Pérez Rojo, Gema, Petidier Torregrossa, Roberto, Pradas Barriga, Irene, Villanueva, Begoña Prado, Prieto Prieto, Fernando, Puertas Cuesta, Francisco Javier, Puyol Antolín, Rafael, Ramos Bacco, Mauricio, Rangel Selvera, Omar, Rexach Cano, Lourdes, Rodríguez Artalejo, Fernando, Rodríguez Mañas, Leocadio, Rodríguez Sánchez, Beatriz, Rodríguez Sánchez, Isabel, Rodríguez Solís, Juan, Lama, María Ángeles Rol de, Romero Macías, Juan Ramón, Romero Rizos, Luis, Ruiz Medrano, Jorge, Ruiz-Moreno, José María, Ruiz Sáenz, Pedro Luis, Salas Carrillo, Mario, Cristóbal Velasco, Esther San, Sánchez Castellano, Carmen, Sánchez Jurado, Pedro Manuel, Nievas, Ginés Sánchez, Escudero, José Manuel Santacruz, Sanz Fernández, Ricardo, Schwingel, Andiara, Scuteri, Angelo, Sierra, Marta I., Sinclair, Alan J., Solano Jaurrieta, Juan José, Soler Moratalla, Isabel, Rodríguez, María del Carmen Soriano, Tarazona Santabalbina, Francisco, Tardáguila García, Noelia, Tasset, Inmaculada, Dorta, Agustín Tejera, Ucha Domingo, Marisol, Urpi Sarda, Mireia, van Leeuwen, Mara, Vega García, Enrique, Verdejo Bravo, Carlos, Verduga Vélez, Rosario, Vial Escolano, Raquel, Vilches Moraga, Arturo, Ribes, José Viña, Walston, Jeremy, Yubero Pancorbo, Raquel, Zambom-Ferraresi, Fabrício, and Zúñiga Gil, Clemente Humberto

Published
2020
Full Text
View/download PDF

56. Oral and Poster Papers Submitted for Presentation at the 5th Congress of the EUGMS 'Geriatric Medicine in a Time of Generational Shift September 3–6, 2008 Copenhagen, Denmark

Author

M. T. Lonergan, B. Hovmand, M. Sánchez Cuervo, M. Tange Kristensen, C. Yau, Stefano Volpato, K. Christensen, K. Guha, J. Duggan, Y. Sawayama, J. F. M. de Jonghe, R. Rosenberg, K. Goupal, N. R. Jørgensen, P. Jordá, H. Kubšová, B. Riou, M. Monami, L. Özdemir, B. R. Duus, J. M. Fernandez Ibanez, Add Neuromed Study, S. Maertens, R. Winder, N. Akdemir, Carmelinda Ruggiero, F. Cambien, D. Bonnet, G. Barban, M. Fuentes, C. Datu, B. Ni Mhaille, D. G. Seymour, Toshio Hayashi, S. Lord, I. Kjeken, E. J. Schaefer, I. Raducanu, E. Tung, A. Truyols Bonet, D. Power, N. Morel, S. Edwards, C. Vigder, K. Promsopa, C. Geny, L. Derame, A. Dukat, A. Vilches-Moraga, K. Lihavainen, Z. Yang, R. M. Pircalabu, P. Huber, C. Eddy, A. Cella, C. Napoli, A. B. L. Pedersen, A. Fedeli, I. Sleiman, P. Weber, W. Kitisomprayoonkul, E. L. Marcus, K. Given, J. Sinclair-Cohen, S. O. Mahony, S. Vinkler, M. Krogseth, S. Otaguro, C. V. U. Øresund, D. Schoevaerdts, R. Pircalabu, B. Brack, H. Sasaki, F. Retornaz, I. Ionescu, M. Dubiel, J. Florian, L. Rokkedal, N. Quinlan, G. Dell’aquila, B. Way, C. Ionescu, T. Bermejo Vicedo, P. Eikelenboom, D. O’neill, T. Koga, A. Kachhia, M. R. Padilla Clemente, G. Batist, K. Moynier Vantieghem, P. Moerland, J. M. Bjordal, A. Pilotto, M. Michelet, R. Shafiei, Mirko Petrovic, J. Sulicka, J. Wagle, T. B. Wyller, J. Hrubanová, B. Stensrød, R. Ferretti, E. Turcu, S. Opris, A. Moreira, A. Zamora Mur, F J Martín Sánchez, N. Cogan, Marcello Maggio, Y. Kreslov, D. Ni Chroinin, G. Hanson, L. Kaiser, P. A. Kocaturk, S. Trainor, P. Takahashi, D. R. Collins, L. Campos, A. Björg Jönsdóttir, M. Cappuccio, V. Massart, T. Pattison, G. Notaridis, S. L. Ktvelä, S. Ghiorghe, Ruth Piers, L. Viati, M. Hollmann, Anja Velghe, Mikko P. Björkman, A. Zwinderman, K. Damkjær, P. Marsden, G. Cuneo, N. Bartoli, P. Gómez De Abia, A. Vilches Moraga, P. Campbell, Didem Sener Dede, B. Kirby, J. Oristrell, C. O’regan, T. Sander Pedersen, A. Hickey, R. Rozzini, B. Jansen, G. Fisher, N. Vogt-Ferrier, E. Kovari, B. Gasperini, K. Kalisvaart, N. Rye Jørgensen, K. Soda, U. Muster, K. Overgaard, J. Duiez-Domingo, M. Urbano, A. Oto, M. C. Cavallini, R. J. Van Marum, F. Gozukara, M. Cabrera Orozco, M. T. Olcoz-Chiva, A. Colvez, M. Di Bari, I. Cilesi, M. Migale, W. He, C. Dwyer, S. Engels, F. Hermmann, D. Small, Adam L. Gordon, Roberto Bernabei, R. Hnidei, C. Gonzalez-Rios, L. B. Husted, B. Dallapiccola, A. Moreau, R. Baron, U. Sveen, D. Chaiwanichsiri, A. Lopez Sierra, D. Villaneau, A. Mathur, G. Vedel Sørensen, P. Hemmi, F. Lattanzio, T. Frühwald, C. Marquis, A. Forest, B. Dalla Piccola, S. Lee, E. Ogawa, F. Coindreau, C. Rada, F. Lally, M. Yamada, K. Bakker, F. Comte, L. C. P. G. M. De Groot, H. L. Jørgensen, A. T. Isk, P. Schwarz, E. Portegijs, M. Kawakami, P. Giannakopoulos, A. Escolante Melich, M. O’ Connor, M. Rafanelli, P. Abete, M. Trabucchi, G. Clpaera, J. Vierendeels, M. Ramos, A. Salpakoski, G. Ziere, M. Ai, T. Fujisawa, K. I. Sørensen, C. Berard, K. Cobbaert, R. Fellin, M. Angel Mas, Phyo K. Myint, Burcu Balam Yavuz, K. Benmedjahed, P. Lampela, S. White, L. del Bianco, E. O. Ospedali Galliera, A. Frøland, L. Kozlov, M. T. Pacitti, P. Dave, B. Oeser, K. Kanaya, M. Rachita, Jean-Pierre Michel, Nadia Sourial, D. O’ Mahony, A. A. Piette, H. O’brien, K. Eiklid, A. J. Cruz-Jentoft, C. Shou, T. Bruun Wyller, J. Geerts, J. Korevaar, A. H. Johansen, P. Nimann Kannegaard, T. Korfitsen, A. Ayub, P. Baker, C. Scarcelli, A. Juszczak, L. S. Seest, A. Blundell, S. Bandinelli, P. A. F. Jansen, A. Maraviglia, E. S. Cankurtaran, B. Orhan, J. Vanakoski, K. J. Kalisvaart, M. Sakai, J. Oh, M. Henry, I. Kiviranta, S. Sanders, T. Mariani, A. H. Ranhoff, Mehmet Cankurtaran, B. Böhmdorfer, A. Tekeira, A. Lund, A. M. J. Maclullich, J. Hayashi, M. J. Lopez-Sanchez, S. M. I. Park, S. Willicombe, B. L. Langdahl, E. Lupeanu, A. Michael, R. Dias, G. Berrut, E. Ruffolo, D. Giet, Marianne Schroll, G. Onose, S. D. Shenkin, J. Driesen, T. Katsuya, C. Moe, M. San-Martin, Koenraad Vandewoude, A. Bambi, E. Shelley, C. Lamanna, B. Mc Eniry, B. Yoo, C. Colombi, H. Ekstrom, P. Gallagher, O. Mkhailova, A. Hnidei, F. P. Cariello, I. Moy, J. M. Vega Andion, G. Balci, F. Orso, W. Schrauwen, Patrizia Mecocci, J. L. Gallais, J. Saunders, M. Koefoed, J. Petrovicova, E. Paredes-Galan, C. Gutiérrez Fernández, Simon Lovestone, N. Berg, N. Weerasuriya, S. Biswas, K. Van Puyvelde, C. Chamot, T. Rantanenv, C. Rosen, K. O’connor, J. Ryg, L. Le Saint, D. A. Jones, M. Boncinelli, S. Baldasseroni, P. Barbisoni, E. Jones, C. F. Ambien, N. Dzerovych, P. Barry, A. Falanga, M. T. Olcoz Chiva, A. Skerris, S. Samandel, Antonio Cherubini, N. Binkley, A. Landi, P. Belli, G. Ditloto, M. Mellingsaeter, K. Wieczorowska-Tobis, L. Alonso Boix, C. Fernandez, V. Strelkova, G. Carmona, S. Amici, S. Mehrabian, J. Lietava, M. Iso-Aho, M. Masotti, I. G. Ftta, J. Carbonero Malberti, I. Carriere, A. Toornvliet, N. Grygoryeva, J. Soubeyrand, M. Cavalieri, Z. Malla, K. D. Pedersen, G. Clapera, J. M. Anton, N. R. Chopra, P. Eiken, S. Kapucu, G. Ventura, E. Cirinei, O. Vazquez, M. Checa, M. Filipa Seabra Pereira, R. Sylvest Mortensen, A. Osawa, J. Cunniffe, M. White, V. Batalha, A. Chatterjee, K. Bjøro, D. Zintchouk, E. Guillemard, R. Vreeswijk, C. Quinn, B. Romboli, G. Pepe, F. Simonsen, B. Morosanu, S. S. Celik, E. Kaykov, C. Bouras, B. Schousboe, N. van der Velde, P. Mowinckel, L. Toutous Trellu, J. Frimann, N. Vergis, T. Wulff, M. Salonoja, H. Doruk, A. Gonzalez, Dominique Benoit, L. Santos, Y. Ben-Israel, B. Grandal Leiros, F. Addante, C. Twomey, C. Sieber, C. Bonomini, P. Ziccardi, D. Carratelli, T. Jørgensen, F. Kasagi, A. Cebrian, M. Frisher, M. S. Brandt, W. Hussain, J. Mora, M. Alen, Maurits Vandewoude, C. Lidy, M. Burke, M. Mørch, A. Lyager, F. Huwez, J González Del Castillo, M. Cankuran, C. Prete, S. Anniss, S. Briggs, E. Bozoglu, S. Sipila, C. Fernandez Rios, H. Nomura, N. Faucher, L. Al-Dhahi, M. Gross, M. G. Longo, C. Schiaffini, H. Petersen, S. Crane, K. Brixen, C. Yucel, A. Leiro Manso, B. Yavuz, J. Petermans, W. Nielsen, T. Jokinen, C. L. Tofteng, D. Wan-Chow-Wah, B. Fantino, I. Barat, M. J. Lopez Sanchez, A. E. Larsen, E. Farrelly, S. Rostoft Kristjansson, J. M. Vega-Andion, V. Andrei, E. Pressel, B. Ni Bhuachalla, Steven Boonen, D. Simoni, M. G. Matera, E. Santillo, R. Sival, Dirk Vogelaers, Anna Skalska, S. Van Der Mark, H. Hirai, V. M. Chisciotti, R. Scoyni, M. Kallinen, A. Lopez-Sierra, E. Paredes Galan, D. Hagedorn, J. B. Lauritzen, Sölve Elmståhl, P. Mikes, M. Cohen, T. Vahlberg, L. E. Matzen, Gerda Verschraegen, H. Blain, E. Rees, R. Melton, T. L. J. Tammela, D. Aw, R. Miralles, E. Lopilato, M. van Zutphen, S. Ghorghe, N. Nissen, M. Lopponen, A. Oestergaard, A. Sorva, F. O’sullivan, M. Vanmeerbeek, A. Sclater, V. Juliebo, M.E. Fuentes Ferrer, S. Prada, E. Bryden, I. Maeve Rea, N. Furusyo, K. Cho, H. Cronin, F. Tigoulet, V. Povoroznyuk, F. Paris, P. Clarkson, P. E. Cotter, S. Rodriguez-Justo, F. Mazzella, E. de Waele, S. Trasciatti, O. Beauchet, E. Mannucci, K. N. Raun, C. Verdejo, S. Pautex, M. M. Mørch, P. Giniès, R. Garavan, J. Nobrega, S. Kinsella, L. Skippari, Howard Bergman, J. E. B. Jensen, T. Lee, P. Godart, B. Montero Errasquin, C. Nyhuus, Reijo S. Tilvis, G. Mancioli, D. Dawe, M. D’imperio, I. Miralles, J. Serra, M. Baglioni, C. Fallon, Y. Tatsukawa, J. Forristall, J. C. Leners, G. D’onofrio, J. de Backer, K. Flekkøy, L. Kyne, V. Dubois-Ferrière, C. Ryan, M. P. Sibret, A. Nesbakken, V. Ochiana, T. Iwamoto, E. Lotti, M. Marchionni, A. Clemmensen, J. Puustinen, S. Amor Andres, L. Wileman, Anette Hylen Ranhoff, S. Gillett, F. Lauretani, M. Gullo, H. Meluzínová, M. Seidahamd, P. de Antonio, A. Sgadari, E. Jespersen, A. Morelli, Palacios Huertas, C. Fraguglia, A. S. Rigaud, H. E. Andersen, B. Wizner, D. Fedak, J. Boddaert, Shaun T. O'Keeffe, D. O. ’Neill, B. Felli, C. Morales Ballesteros, S. Mcintosh, P. Such, O. Akyol, I. S. Young, J. M. Guralnik, A. Leiro-Manso, L. P. D’ambrosio, S. Rooij, G. Gold, H. Lee, C. Sohrt, A. Egan, D. Susanne Nielsen, C. Gravina, P. Rinaldi, C. Lestrup, S. F. Syed Farooq, M. Nuotio, L. Rexach Cano, C. Maraldi, F. Mangiaasche, Z. Mikes, E. M. Damsgaard, C. Di Serio, S. Pecchioni, S. Caplan, E. Gonzalez, M. Baccini, Y. Caine, J. Gladman, J. M. Ribera, B. Lundgren, V. Sharma, M. Morocutti, Sara Ercolani, B. H. C. Stricker, C. Popescu, M. Carpena-Ruiz, M. Verny, B. Hofman, A. Ungar, Y. Kumei, E. Topikova, L. Franceschi, S. Hussain, V. Serafini, K. Shipman, F. Sioulis, T. Coughlan, S. Bhat, B. Comert, K. Engedal, B. Kream, A. Iguchi, D. F. Vitale, M. Fornal, K. Kristiansen, I. Palma-Reis, E. Sixt, C. H. Foss, R. Rizzoli, M. Bartley, B. Fure, P. Freitas, C. Fernández Alonso, R. Njemini, F. Kelleher, A. Zamora Catevilla, S. Hoeck, F. Rashidi, J.M. Ribera Casado, M. Honing, A. Rajska-Neumann, B. D. Pedersen, A. Martins, C. M. J. Van Der Linden, D. Sharpe, R. Grue, Denis O'Mahony, J. Van der Heyden, J. Cristoffersen, Marianna Noale, U. Sommeregger, V. Goffredo, A. Qvist, Y. Akkuþ, M. T. E. Puts, M. Luque, M. P. De Antonio García, T. Takagi, N. Carroll, A. Salakowski, M. Belladonna, A. Hylen Ranhoff, S. Otokozawa, C. Ekdahl, E. Delgado Silveira, Stijn Blot, H. Mcgee, U. Senin, G. C. Parisi, S. Pedersen, F. Rengo, A. Renom, E. Vestbo, Y. Akkus, G. Van Hal, S. Murphy, V. Ducasse, G. Ryzhak, M. I. Arranz Peña, W. Knol, V. Lesauskaite, F. Patacchini, S. Abe, M. Narro-Vidal, C. Lund, N. Hayashi, M. van Breemen, H. Ohnishi, M. Torrente-Carballido, B. Bogen, H. Kayihan, Z. Tuna, C. Verdejo-Bravo, B. Battacharya, F. M. Borgbjerg, Kudret Aytemir, A. C. Drenth-Van Maanen, F. Gori, O. Duems, T.J.M. van der Cammen, Servet Ariogul, P. Villarroel, M. Kat, N. Petitpierre, I. Akyar, M. Franceschi, M. Ohishi, S. Cassano, Roy L. Soiza, T. Patel, A. M. Herghelegiu, M. Clarfield, S. Ballentyne, L. Lambertucci, Cm. Pena, A. Bayer, A. Salam, E. Moriarty, C. Roux, Y. Takasugi, M. García, C. Rodriguez-Pascual, P. Mikus, Y. Akyar, M. Torrente Carballido, V. Vayda, F. Rønholt, M. Khayat, K. Ina, O. Hazer, M. Falconer, H. N. Jacobsen, R. Custureri, H. Kasem, T. Bandholm, A. Allue Bergua, M. Levi, R. Rehman, M. Monette, C. Verdejo Bravo, O. Millot, N. Caffrey, Y. Kano, C. Cherubini, J. Kolesar, S. Maeshima, J. Fox, P. Aarnio, E. Henderson, J. Monette, M. MacMahon, L. Rytter, J. Nurminen, A. Abbas, A. S. Whitehead, G. Longobardi, Zekeriya Ulger, M. Hamada, A. Sofia Duque, Luigi Ferrucci, P. Lavikainen, J. Kennedy, I. Saez, E. Hegarty, Stefania Maggi, J. Touchon, A. Chandra, A. Bhangu, M. Labib, A. Rnould, A. Bojan, S. Mukherjee, N. Ferrara, F. Raschilas, G. Popescu, C. Annweiler, D. Hevey, D. Seripa, C. Danneels, I. Crome, M. Karlsson, Y. Kamiya, C. Carvell, I. Trani, T. van der Ploeg, G. Zulian, J. Bencke, V. Curran, P. Gherasim, B. Sejtved, R. Meade, Rose Anne Kenny, V. Curiale, A. Yu-Ballard, E. Azevedo, A. Leiros, P. Gil Gregorio, J. Gonzalez Armengol, H. Rakugi, M. C. Esculier, O. Poire, R. Raz, R. Gugliotta, M. Carpena Ruiz, Tony Mets, Ivan Bautmans, T. Karasevskaya, P. Eoin Cotter, T. Masud, C. Jeandel, K. Leckie, J. P. Lopes, R. Isoaho, A. E. Evans, F. Lacoin, C. Cho, B. Vincent, M. Lazaro, R. Cecchetti, M. Carpena, A. Kavanagh, S. Juhl Pedersen, Niccolò Marchionni, C. Swine, François Herrmann, G. O. Kavas, F. J. Garcia Garcia, S. Quintela, G. I. Prada, C. Hertogh, S. Sun Kapucu, P. Granberg, S. Byrne, R. Mcdermott, R. Van Der Stichele, A. M. Mello, A. Waldir Bezerra, J. de Jonghe, L. F. Moreno Ramiez, A. de Tena Fontaneda, M. H. Saldanha, H. Kehlet, G. V. Sørensen, M. Jylhä, J. Silvestre, K. Czabanowska, L. Gowran, F. Albertí Homar, M. de Saint-Hubert, R. Huupponen, P. le Lous, T. Bertsch, P. Dieppe, R. Topor-Madry, R. Van Gara, W. Bemelmans, V. Polcarová, C. Donnellan, B. Jørgensen, G. Leandro, S. L. Kivela, C. Boubakri, Sirpa Hartikainen, K. Ferguson, Z. Barrou, E. Costanzi, H. Hilleret, L. Danbaek, A. O’hanlon, C. Hürny, O. G. Olaru, V. Seux, C. Divoy, M. Mowe, E. Holm, H. J. Heppner, J. Martin, M. Isik, B. Gryglewska, A. Lilja, E. Romero, I. Pillay, V. Kijowska, M. Therese Lonergan, A. Alfaro Acha, M. Uyanik, A. Gabelle, P. Bueso, S. Sinha, M. Corritore, T. Shingo, E. Lacey, L. Cascavilla, R. Sulkava, K. Terumalai, S. Pellerito, Gaetano Crepaldi, R. Moe-Nilssen, Francesco Cacciatore, J. Breda, J. M. Del Rey, J. Teixeira, N. B. Nielsen, E. Granot, D. Speijer, S. A. Anstey, G. Masotti, I. G. Fita, S. Krajèík, P. Brynningsen, S. Maeda, N. Vanden Noortgate, J. Wiersinga, M. Teixeira Veríssimo, J. Cooke, N. Van Den Noortgate, K. Daly, M. M. Bisschop, A. Galmés Truyols, W.A. van Gool, J. Fernandez Soria, C. Sánchez Castellano, A. M. Cervera, E. Mossello, T. Lindhardt, C. Boulanger, E. Oziol, C. Hendriksen, A. M. Pazienza, L. Farner, P. Bastiani, F. Horgan, A. Deniz, P. Ammann, H. Takeoka, J. Lauritsen, L. Sandvik, S. S. Kapucu, I. Nakagawa, A. Jung, L. Brewer, Anne-Marie Schott, S. Zanieri, A. Teixeira, G. Parisi, P. Lund Nielsen, J. Holckova, P. Alcalde, B. Whelan, K. Toyoda, B. Dieudonne, G. Guerra, Meltem Halil, E. Garcia-Villar, R. Paz Maya, C. E. Mogensen, M. O’connor, A. Bonnerup Vind, L. Vich Martorell, F. Tarantini, Katarzyna Szczerbińska, I. Ozerov, R. Turk, M. Kamigaki, E. Mirewska, H. Bayes, S. Arino, P. Lyngholm-Kxærby, B.C. van Munster, F. Konishi, A. Morrione, C. Pena, P. Harbig, D. Gradinaru, F. Kee, B. Knold, L. Aiello, T. de Man, Renaat Peleman, Taina Rantanen, P. Birschel, P. Crome, R. Meyling, V. Khavinson, D. H. Kim, T. Luukkaala, Q. Garcia, K. Elkholy, D. Gillain, M. L. Seux, S. Greffard, P. Kjear, S. Sihvonen, Patricia M. Kearney, Tomasz Grodzicki, F. Favier, Dominique Vandijck, E. Palummeri, F. Caldi, Y. Parel, E. Jorge, L. O’connor, S. Dahlin Ivanoff, L. Tiret, K. Adie, G. Lucchetti, M. Lauridsen, A. C. Berggren, M. Simon, D. Adane, P. O. Lang, and V. Niro

Subjects
Gerontology, Geriatrics, 0303 health sciences, medicine.medical_specialty, Nutrition and Dietetics, 030309 nutrition & dietetics, Geriatrics gerontology, business.industry, media_common.quotation_subject, Alternative medicine, Medicine (miscellaneous), 03 medical and health sciences, Presentation, 0302 clinical medicine, medicine, 030212 general & internal medicine, Geriatrics and Gerontology, business, Quality of Life Research, media_common
Published
2008
Full Text
View/download PDF

59. Does 8-Foot Walk Time Predict Cognitive Decline in Older Mexicans Americans?

Author

Kenneth J. Ottenbacher, Mukaila A. Raji, Kyriakos S. Markides, Ana Alfaro-Acha, and Soham Al Snih

Subjects
Gerontology, Geriatrics, education.field_of_study, medicine.medical_specialty, business.industry, Visual impairment, Population, Cognitive disorder, medicine.disease, Quartile, medicine, Marital status, Geriatrics and Gerontology, medicine.symptom, Cognitive decline, business, education, human activities, Body mass index
Abstract

OBJECTIVES: To examine the association between 8-foot time walk and change in cognitive function over time in older Mexican Americans. DESIGN: Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (1993–2001). SETTING: Five southwestern states: Texas, New Mexico, Colorado, Arizona, and California. PARTICIPANTS: Two thousand seventy noninstitutionalized Mexican-American men and women aged 65 and older who had a Mini-Mental State Examination (MMSE) score of 21 or greater at baseline. MEASUREMENTS: Sociodemographic factors (age, sex, education, marital status), MMSE score, 8-foot walk time, body mass index, medical conditions (stroke, heart attack, diabetes mellitus, depression, and hypertension), and near and distant visual impairment. RESULTS: Using general linear mixed models, it was found that subjects with the slowest 8-foot walk time had a significantly greater rate of cognitive decline over 7 years than subjects with the fastest 8-foot walk time. There was a significant 8-foot walk time–by-time interaction with MMSE scores. Subjects in the lowest 8-foot walk time quartile had a greater cognitive decline over 7 years (estimate=−0.32, SE=0.08; P

Published
2007
Full Text
View/download PDF

60. Androgen Treatment and Muscle Strength in Elderly Men: A Meta-Analysis

Author

Ana Alfaro Acha, Margaret E. Ottenbacher, Glenn V. Ostir, Allison Ottenbacher, and Kenneth J. Ottenbacher

Subjects
medicine.medical_specialty, medicine.drug_class, business.industry, medicine.disease, Androgen, Confidence interval, law.invention, Clinical trial, Randomized controlled trial, law, Internal medicine, Meta-analysis, Dihydrotestosterone, Sarcopenia, medicine, Physical therapy, Geriatrics and Gerontology, business, Testosterone, medicine.drug
Abstract

OBJECTIVES: To review published, randomized trials examining the effect of androgen treatment on muscle strength in older men. DESIGN: Systematic review using meta-analysis procedures. SETTING: Computerized and manual searches. PARTICIPANTS: MEDLINE, EMBASE, CINAHL, and the Cochrane Register were searched for trials. Key words included testosterone, androgen, sarcopenia, muscle loss, aged, aging, elderly, older, geriatric, randomized controlled trials, and controlled clinical trials. Sixty-five nonoverlapping studies were found. Meta-analysis methods were used to evaluate the 11 randomized, double-blind trials. INTERVENTION: Testosterone or dihydrotestosterone (DHT) replacement therapy in healthy men aged 65 and older. MEASUREMENTS: Tests of muscle strength. RESULTS: The studies included 38 statistical comparisons. The mean g-index (gi) adjusted for sample size was 0.53 (95% confidence interval (CI)=0.21–0.86). Subanalyses revealed larger effects for measures of lower extremity muscle strength (gi=0.63, 95% CI=0.03–1.28) than for upper extremity muscle strength (gi=0.47, 95% CI=0.12–0.84). A larger mean g-index was found for injected (gi=0.95, 95% CI=0.33–1.58) than topical (gi=0.26, 95% CI=0.08–0.42) or oral (gi=−0.21, 95% CI=−1.40–1.02) administration of testosterone/DHT. Effect sizes were related to study characteristics such as subject attrition and design-quality ratings. Sensitivity analyses revealed that the elimination of one study reduced the mean g-index from 0.53 to 0.23. CONCLUSION: The results suggest that testosterone/DHT therapy produced a moderate increase in muscle strength in men participating in 11 randomized trials. One study influenced the mean effect size.

Published
2006
Full Text
View/download PDF

61. Cognitive Status, Body Mass Index, and Hip Fracture in Older Hispanic Adults

Author

Glenn V. Ostir, Kenneth J. Ottenbacher, Kyriakos S. Markides, and Ana Alfaro-Acha

Subjects
Gerontology, Geriatrics, Hip fracture, medicine.medical_specialty, business.industry, Incidence (epidemiology), Hazard ratio, Anthropometry, medicine.disease, Confidence interval, medicine, Physical therapy, Geriatrics and Gerontology, business, Prospective cohort study, Body mass index
Abstract

OBJECTIVES: To examine the interactive effect of cognition and body weight on hip fracture. DESIGN: A 7-year (1993–2000) prospective cohort study. SETTING: Five southwestern states (Texas, New Mexico, Arizona, Colorado, and California). PARTICIPANTS: Noninstitutionalized Mexican Americans (N=2,653) aged 65 and older and free of hip fracture at baseline interview. MEASUREMENTS: Incidence of hip fracture at 2-, 5-, and 7-year follow-up interviews. Body weight and cognition were measured using body mass index (BMI) and Mini-Mental State Examination score, respectively. Covariates included sociodemographics, self-reported medical conditions, visual acuity, and Short Physical Performance Battery. RESULTS: A significant interaction between BMI and hip fracture was found in persons with cognitive impairment (hazard ratio =0.91, 95% confidence interval=0.85–0.98; P=.02), after adjusting for covariates. In the lowest BMI category, the hip fracture rate in cognitively impaired subjects was more than four times the hip fracture rate for subjects who were not cognitively impaired with the same BMI (34.6% vs 8.7%). Hip fracture rates in the highest BMI category were similar in persons with and without cognitive impairment (9.3% vs 6.1%). CONCLUSION: Low cognitive function increased the conditional association between BMI and hip fracture in older Mexican Americans. The relationship between BMI and cognition is potentially important in identifying persons at risk for hip fracture and supports the need to include cognitive and anthropometric measures in the assessment of hip fracture risk into osteoporosis screening programs.

Published
2006
Full Text
View/download PDF

62. The prevalence of frailty syndrome in an older population from Spain. The Toledo Study for Healthy Aging

Author

F J, Garcia-Garcia, G, Gutierrez Avila, A, Alfaro-Acha, M S, Amor Andres, M, De Los Angeles De La Torre Lanza, M V, Escribano Aparicio, S, Humanes Aparicio, J L, Larrion Zugasti, M, Gomez-Serranillo Reus, F, Rodriguez-Artalejo, L, Rodriguez-Manas, and Teresa, Moreno Casbas

Subjects
Gerontology, Male, Cross-sectional study, Frail Elderly, Population, Frailty syndrome, Physical fitness, Medicine (miscellaneous), Comorbidity, Motor Activity, Quality of life, Activities of Daily Living, Weight Loss, medicine, Prevalence, Humans, Disabled Persons, Muscle Strength, education, Exercise, Gait, Geriatric Assessment, Depression (differential diagnoses), Fatigue, Aged, Aged, 80 and over, education.field_of_study, Nutrition and Dietetics, Muscle Weakness, business.industry, Age Factors, Syndrome, medicine.disease, Physical Fitness, Spain, Marital status, Female, Geriatrics and Gerontology, business
Abstract

To assess the prevalence of the frailty syndrome and its associated variables among the older adult population in the province of Toledo (Spain). Data were taken from the Toledo Study for Healthy Aging, a population-based study conducted on 2,488 individuals aged 65 years and older. Study participants were selected by a two-stage random sampling from the municipal census of Toledo, covering both institutionalized and community dwelling persons from rural and urban settings. Data were collected from 2006 to 2009, and included information on social support, activities of daily living, comorbidity, physical activity, quality of life, depressive symptoms, and cognitive function. In addition, a nurse collected anthropometric data, conducted tests of physical performance (walk speed, upper and lower extremities strength, and the stand-and-sit from a chair test) and obtained a blood sample. The diagnosis of the frailty syndrome was based on the Fried criteria (weakness, low speed, low physical activity, exhaustion, and weight loss). In total, 41.8% (95% confidence interval [CI] 39.4–44.2%) of the study participants were prefrail, and 8.4% (95% CI 7.1–9.8%) were frail. There were no differences in the prevalence of frailty by sex, level of education, occupation, marital status, or place of residence. The frequency of the frailty syndrome increased with age, and was higher in those with disability, depression, hip fracture and other comorbidity, such as cardiovascular disease and disorders of the central nervous system. The prevalence of the frailty syndrome in older Spanish adults is high and similar to that reported in other populations in the Mediterranean basin.

Published
2011

64. Does 8-foot walk time predict cognitive decline in older Mexicans Americans?

Author

Ana, Alfaro-Acha, Soham, Al Snih, Mukaila A, Raji, Kyriakos S, Markides, and Kenneth J, Ottenbacher

Subjects
Male, Time Factors, Socioeconomic Factors, Predictive Value of Tests, Mexican Americans, Linear Models, Southwestern United States, Humans, Female, Walking, Cognition Disorders, Aged
Abstract

To examine the association between 8-foot time walk and change in cognitive function over time in older Mexican Americans.Data used are from the Hispanic Established Population for the Epidemiological Study of the Elderly (1993-2001).Five southwestern states: Texas, New Mexico, Colorado, Arizona, and California.Two thousand seventy noninstitutionalized Mexican-American men and women aged 65 and older who had a Mini-Mental State Examination (MMSE) score of 21 or greater at baseline.Sociodemographic factors (age, sex, education, marital status), MMSE score, 8-foot walk time, body mass index, medical conditions (stroke, heart attack, diabetes mellitus, depression, and hypertension), and near and distant visual impairment.Using general linear mixed models, it was found that subjects with the slowest 8-foot walk time had a significantly greater rate of cognitive decline over 7 years than subjects with the fastest 8-foot walk time. There was a significant 8-foot walk time-by-time interaction with MMSE scores. Subjects in the lowest 8-foot walk time quartile had a greater cognitive decline over 7 years (estimate=-0.32, SE=0.08; P.001) than those in the highest quartile. This association remained statistically significant after controlling for potential confounding factors.Slow 8-foot walk time in older Mexican-American adults without cognitive impairment at baseline was an independent predictor of MMSE score decline over a 7-year period. Slow 8-foot walk time may be an early marker for older adults in a predementia state who may benefit from early-intervention programs to prevent or slow cognitive decline.

Published
2007

65. Androgen treatment and muscle strength in elderly men: A meta-analysis

Author

Kenneth J, Ottenbacher, Margaret E, Ottenbacher, Allison J, Ottenbacher, Ana Alfaro, Acha, and Glenn V, Ostir

Subjects
Male, Hormone Replacement Therapy, Humans, Dihydrotestosterone, Testosterone, Muscle Strength, Article, Aged, Randomized Controlled Trials as Topic
Abstract

To review published, randomized trials examining the effect of androgen treatment on muscle strength in older men.Systematic review using meta-analysis procedures.Computerized and manual searches.MEDLINE, EMBASE, CINAHL, and the Cochrane Register were searched for trials. Key words included testosterone, androgen, sarcopenia, muscle loss, aged, aging, elderly, older, geriatric, randomized controlled trials, and controlled clinical trials. Sixty-five nonoverlapping studies were found. Meta-analysis methods were used to evaluate the 11 randomized, double-blind trials.Testosterone or dihydrotestosterone (DHT) replacement therapy in healthy men aged 65 and older.Tests of muscle strength.The studies included 38 statistical comparisons. The mean g-index (g(i)) adjusted for sample size was 0.53 (95% confidence interval (CI) = 0.21-0.86). Subanalyses revealed larger effects for measures of lower extremity muscle strength (g(i) = 0.63, 95% CI = 0.03-1.28) than for upper extremity muscle strength (g(i) = 0.47, 95% CI = 0.12-0.84). A larger mean g-index was found for injected (g(i) = 0.95, 95% CI = 0.33-1.58) than topical (g(i) = 0.26, 95% CI = 0.08-0.42) or oral (g(i) = -0.21, 95% CI = -1.40-1.02) administration of testosterone/DHT. Effect sizes were related to study characteristics such as subject attrition and design-quality ratings. Sensitivity analyses revealed that the elimination of one study reduced the mean g-index from 0.53 to 0.23.The results suggest that testosterone/DHT therapy produced a moderate increase in muscle strength in men participating in 11 randomized trials. One study influenced the mean effect size.

Published
2006

66. Cognitive status, body mass index, and hip fracture in older Hispanic adults

Author

Ana, Alfaro-Acha, Glenn V, Ostir, Kyriakos S, Markides, and Kenneth J, Ottenbacher

Subjects
Aged, 80 and over, Male, Hip Fractures, Incidence, Hispanic or Latino, United States, Article, Body Mass Index, Cognition, Risk Factors, Humans, Female, Prospective Studies, Cognition Disorders, Aged, Follow-Up Studies
Abstract

To examine the interactive effect of cognition and body weight on hip fracture.A 7-year (1993-2000) prospective cohort study.Five southwestern states (Texas, New Mexico, Arizona, Colorado, and California).Noninstitutionalized Mexican Americans (N=2,653) aged 65 and older and free of hip fracture at baseline interview.Incidence of hip fracture at 2-, 5-, and 7-year follow-up interviews. Body weight and cognition were measured using body mass index (BMI) and Mini-Mental State Examination score, respectively. Covariates included sociodemographics, self-reported medical conditions, visual acuity, and Short Physical Performance Battery.A significant interaction between BMI and hip fracture was found in persons with cognitive impairment (hazard ratio =0.91, 95% confidence interval=0.85-0.98; P=.02), after adjusting for covariates. In the lowest BMI category, the hip fracture rate in cognitively impaired subjects was more than four times the hip fracture rate for subjects who were not cognitively impaired with the same BMI (34.6% vs 8.7%). Hip fracture rates in the highest BMI category were similar in persons with and without cognitive impairment (9.3% vs 6.1%).Low cognitive function increased the conditional association between BMI and hip fracture in older Mexican Americans. The relationship between BMI and cognition is potentially important in identifying persons at risk for hip fracture and supports the need to include cognitive and anthropometric measures in the assessment of hip fracture risk into osteoporosis screening programs.

Published
2006

67. Handgrip strength and cognitive decline in older Mexican Americans

Author

Kyriakos S. Markides, Yong Fang Kuo, Ana Alfaro-Acha, Soham Al Snih, Mukaila A. Raji, and Kenneth J. Ottenbacher

Subjects
Gerontology, Male, Aging, Population, Risk Assessment, Article, Cohort Studies, Cognition, Sex Factors, Predictive Value of Tests, Hand strength, Mexican Americans, Medicine, Humans, Cognitive decline, education, Prospective cohort study, Aged, education.field_of_study, Psychological Tests, Hand Strength, business.industry, Standard error, Quartile, Socioeconomic Factors, Female, Geriatrics and Gerontology, business, human activities, Body mass index, Cohort study
Abstract

Background. Cognitive decline and dementia are associated with disability and premature death in old age. We examined whether low handgrip strength predicts subsequent cognitive decline in older Mexican Americans. Methods. We worked with a 7-year prospective cohort of 2160 noninstitutionalized Mexican Americans aged 65 years or older from the Hispanic Established Population for the Epidemiological Study of the Elderly (H-EPESE) who had a Mini-Mental State Examination (MMSE) score � 21 at baseline. Measures included: (i) sociodemographic factors (age, gender, and education), handgrip strength, and near and distant visual impairment from baseline interview; and (ii) MMSE, body mass index (BMI), and medical conditions (stroke, heart attack, diabetes, depression, and hypertension) from four waves of data collection. Results. Using general linear mixed models, we found a significant trend with scores in the lowest quartile of handgrip strength at baseline to be associated with lower MMSE scores over time (estimate ¼� 1.28, standard error ¼ 0.16; p , .0001). There was a significant handgrip Strength-by-Time interaction with MMSE scores. Participants in the lowest handgrip strength quartile had a greater cognitive decline over time (estimate ¼� 0.26, standard error ¼ 0.07; p , .001) than did those participants in the highest quartile. This association remained statistically significant after controlling for potential confounding factors. Conclusion. Older Mexican Americans with reduced handgrip strength at baseline demonstrated a statistically significant decline in cognitive function over a 7-year period. By contrast, participants in the highest handgrip strength quartile maintained a higher level of cognitive function.

Published
2006

72. Colaboradores

Author

Abellan van Kan, Gabor, Abizanda Soler, Pedro, Alarcón Alarcón, Teresa, Alfaro Acha, Ana, Alfonso Silguero, Sergio Alexandre, Alonso Bouzón, Cristina, Alonso Fernández, Teresa, Alonso Renedo, Javier, Alves Lourenço, Roberto, Angulo Frutos, Javier, Arche Coto, José Miguel, Areosa Sastre, Almudena, Ariza Zafra, Gabriel, Arriola Manchola, Enrique, Avellana Zaragoza, Juan Antonio, Balducci, Lodovico, Bayer, Anthony, Baztán Cortés, Juan José, Béland, François, Belenguer Varea, Ángel, Bermeo, Sandra, Bermúdez Menéndez de la Granda, Manuel, Betancor Santana, Évora, Borrás Blasco, Consuelo, Burcet Pérez, Silvia, Caballero Mora, María Ángeles, Cabré Roure, Mateu, Cadore Lusa, Eduardo, Calderón, Verónica, Callejas González, Francisco Javier, Cano Gutiérrez, Carlos Alberto, Carbonell Collar, Antonio, Casas Herrero, Álvaro, Castro Rodríguez, Marta, Chaves, Paulo H.M., Chodzko-Zajko, Wojtek, Clavé Civit, Pere, Crespo Santiago, Dámaso, Cuervo, Ana María, Cuesta Triana, Federico, de Costa Ruiz, Jorge, de la Fuente del Rey, Mónica, de la Fuente Gutiérrez, Carlos, del Pozo Guerrero, Francisco, Doménech Pascual, Juan Ramón, Domínguez Martín, Laura, Duque, Gustavo, Durio Calero, Enrique Antonio, El Assar de la Fuente, Mariam, Esquinas Requena, José Luis, Gutiérrez Robledo, Luis Miguel F., Fernández de Trocóniz Fernández, Iñaki, Fernández Fernández, María, Fernández Martínez, Nuria, Fernández Rodríguez, Esperanza, Fernández Viadero, Carlos, Flores Ruano, Teresa, Fontecha Gómez, Benito, Gambini Buchón, Juan, García García, Francisco José, García Navarro, José Augusto, Garreta Burrel, Marisa, Garrido Cid, María Jesús, Gil Gregorio, Pedro, Gómez Arnedo, Llanos, Gómez Fernández, Marisol, Gómez Pavón, Javier, González Guerrero, José Luis, González Montalvo, Juan Ignacio, González-Colaço Harmand, Magali, Guerrero Díaz, María Teresa, Gutiérrez Rodríguez, José, Heras Benito, Manuel, Hernández Zamora, Paulo, Hernández Zegarra, Pablo Alberto, Hornillos Calvo, Mercedes, Ibarzábal Aramberri, Xabier, Inglés de la Torre, Marta, Izquierdo Redín, Mikel, Jiménez Huete, Adolfo, Jiménez Muela, Francisco, Jiménez Rojas, Concepción, Jordán Bueso, Joaquín, Júdez Navarro, Enrique, Juncos Martínez, Gema, Kireev, Roman, Kurtis Urra, Mónica M., Laosa Zafra, Olga, León Ortiz, Matilde, López Arrieta, Jesús María, López Chicharro, José, López-Dóriga Bonnardeaux, Pedro, Lozano Berrio, Vicente, Luengo Márquez, Carmen, Madrid Pérez, Juan Antonio, Mansilla Lozano, David, Manzarbeitia Arambarri, Jorge, Martín Sebastiá, Asunción, Martín Sebastiá, Elena, Martínez, Iveris Luz, Martínez Montandón, Álvaro, Martínez Ramírez, Alicia, Martínez Reig, Marta, Martínez Velilla, Nicolás, Mazoteras Muñoz, Virginia, Millor Muruzábal, Nora, Miralles Basseda, Ramón, Mohedano Molano, Julia, Montero Moreno, Javier Antonio, Montero Odasso, Manuel, Montes Paixão Júnior, Carlos, Morales Martínez, Fernando, Naudí Farré, Alba, Navarrete-Reyes, Ana Patricia, Navarro López, José Luis, Núñez Ares, Ana, Ortega Fernández, Omar, Palumbo, Claudio, Pamplona Gras, Reinald, Pardal Fernández, José Manuel, Pareja Sierra, Teresa, Parodi García, José Francisco, Peláez, Martha, Pérez Díaz, David Salomón, Pérez-Jara Carrera, Javier, Petidier Torregrossa, Roberto, Portero-Otín, Manuel, Prado Esteban, Florentino, Prieto Prieto, Fernando, Puertas Cuesta, Francisco Javier, Ramos Bacco, Mauricio, Rangel Selvera, Omar, Rexach Cano, Lourdes, Riva Amarante, Elena, Rodríguez Mañas, Leocadio, Rodríguez Solís, Juan, Rol de Lama, María Ángeles, Romero Rizos, Luis, Ruiz Arregui, Liliana, Ruiz-Moreno, José María, Sáez Méndez, Lourdes, San Cristóbal Velasco, Esther, Sánchez Jurado, Pedro Manuel, Sánchez Nievas, Ginés, Sánchez Simón-Talero, Rafaela, Sanz Fernández, Ricardo, Schwingel, Andiara, Scuteri, Angelo, Solano Jaurrieta, Juan José, Suárez García, Francisco, Tardáguila García, Noelia, Tártalo Hernández, David, Tasset, Inmaculada, Tresguerres, Ana F., Tresguerres, Jesús Á.F., Vara Ameigeiras, Elena, Vega García, Enrique, Verdejo Bravo, Carlos, Verduga Vélez, Rosario, Vilches Moraga, Arturo, Villalba Mora, Elena, Viña Ribes, José, Yubero Pancorbo, Raquel, Zunzunegui, María Victoria, and Zúñiga Gil, Clemente H.

Published
2015
Full Text
View/download PDF

74. Cut-Off Points for Low Relative 30-s Sit-to-Stand Power and Their Associations With Adverse Health Conditions.

Author

Garcia-Aguirre M, Baltasar-Fernandez I, Alcazar J, Losa-Reyna J, Alfaro-Acha A, Ara I, Rodriguez-Mañas L, Alegre LM, and Garcia-Garcia FJ

Subjects
Humans, Male, Female, Aged, Aged, 80 and over, Activities of Daily Living, Geriatric Assessment methods, Frailty epidemiology, Muscle Strength physiology
Abstract

Background: Despite muscle power derived from the 5-rep sit-to-stand (STS) test having been demonstrated to be a valuable biomarker in older individuals, there is limited information regarding muscle power derived from the 30-s STS test, a widely used test in the clinical setting. This study aimed (i) to compare relative 30-s STS power values between older men and women, (ii) to identify cut-off points for low relative 30-s STS power, (iii) to compare the prevalence of low relative STS power between sexes and (iv) to evaluate the association of low relative 30-s STS power with adverse conditions in older people., Methods: A total of 1475 community-dwelling older adults (65-98 years; 45% men) from the Toledo Study for Healthy Aging were included. Relative STS power was assessed using the 30-s STS test and the Alcazar's equation. Adverse health conditions considered encompassed frailty, depression, disability in basic (BADL) and instrumental activities of daily living (IADL), cognitive impairment and low habitual gait speed (HGS)., Results: Relative STS power decreased linearly at an average rate of 1.0% year -1 in men and 1.5% year -1 in women. The cut-off points for low relative STS power were 2.53 and 2.01 W·kg -1 for men and women, respectively. The prevalence of low relative STS power was significantly lower in older men compared with older women (43.5% vs. 50.0%, respectively; p = 0.005). In men, low relative STS power was associated with frailty (OR [95% CI] = 4.4 [2.4-8.0]), cognitive impairment (OR [95% CI] = 1.7 [1.0-2.7]), disability in BADL (OR [95% CI] = 4.5 [1.5-13.8]) and low HGS (OR [95% CI] = 3.4 [1.9-5.9]). In women, low relative STS power was associated with frailty (OR [95% CI] = 5.2 [3.5-7.7]), disability in BADL (OR [95% CI] = 4.3 [1.8-9.9]) and IADL (OR [95% CI] = 3.1 [2.2-4.3]) and low HGS (OR [95% CI] = 6.1 [2.8-13.1]). No associations were found between low relative STS power and disability in IADL or depression in men, nor between low relative STS power and cognitive impairment or depression in women., Conclusion: Relative STS power decreased with increasing age in both men and women. The provided sex-specific cut-off points for low relative STS power using the 30-s STS test adequately identified older people with frailty and were associated with an increased risk of experiencing adverse conditions., (© 2025 The Author(s). Journal of Cachexia, Sarcopenia and Muscle published by Wiley Periodicals LLC.)

Published
2025
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results