51. Effects of medium-term green tea extract supplementation combined with CrossFit workout on blood antioxidant status and serum brain-derived neurotrophic factor in young men: a pilot study
- Author
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Aleksandra Żebrowska, Agnieszka Gdańska, Tomasz Podgórski, Ewa Sadowska-Krępa, Ilona Pokora, and Przemysław Domaszewski
- Subjects
0301 basic medicine ,Male ,CrossFit ,Antioxidant ,medicine.medical_treatment ,Pilot Projects ,Green tea extract ,Antioxidants ,Lipid peroxidation ,chemistry.chemical_compound ,0302 clinical medicine ,Blood plasma ,chemistry.chemical_classification ,Nutrition and Dietetics ,Glutathione peroxidase ,Catalase ,lcsh:RC1200-1245 ,lcsh:Nutrition. Foods and food supply ,Research Article ,Prooxidant-antioxidant balance ,medicine.medical_specialty ,lcsh:TX341-641 ,03 medical and health sciences ,Young Adult ,Oxygen Consumption ,Internal medicine ,medicine ,TBARS ,Humans ,lcsh:Sports medicine ,Exercise ,Glutathione Peroxidase ,030109 nutrition & dietetics ,Tea ,business.industry ,Plant Extracts ,Superoxide Dismutase ,Brain-Derived Neurotrophic Factor ,030229 sport sciences ,Glutathione ,Endocrinology ,BDNF ,chemistry ,Dietary Supplements ,Exercise Test ,Uric acid ,Lipid Peroxidation ,business ,Food Science - Abstract
Background Potential health benefits are attributed to the antioxidant properties of green tea polyphenolic compounds. The main aim of the study was to evaluate the effects of a six-week green tea extract (GTE) supplementation combined with CrossFit workout on blood antioxidant status and serum brain-derived neurotrophic factor (BDNF) in men. Methods Sixteen young males involved in CrossFit training were randomized into two groups supplemented with GTE or placebo for six weeks. Each participant performed an exercise test for the evaluation of maximum oxygen uptake (VO2max) twice, i.e., before starting (1st trial) and after completing the supplementation combined with CrosFit workout (2nd trial). Venous blood samples were drawn at rest, immediately post-test and after one hour of recovery in order to estimate activities of antioxidant enzymes (superoxide dismutase [SOD], catalase [CAT], glutathione peroxidase [GPx], reduced glutathione [GR]), non-enzymatic antioxidants (reduced glutathione [GSH], uric acid [UA], total phenolics), total antioxidant capacity (FRAP), lipid peroxidation products (TBARS), and BDNF. Results Except for a significantly higher SOD activity and FRAP level recorded at rest and post-exercise in the 2nd trial compared to the corresponding values in the 1st trial, no significant differences were recorded among other assayed measures such as CAT, GPx, GR, GSH and BDNF. Moreover, a percentage increase in FRAP level was twice as high after six weeks’ GTE consumption than after placebo. Regardless of the trial, an increase in plasma UA concentration and a decrease in plasma total phenolics level were observed after exercise test. Plasma TBARS concentrations were significantly higher in PLA group after six weeks’ CrossFit training, while in GTE group they were slightly lower compared to the corresponding values in the 1st trial. Moreover, there was a significant inverse correlation between FRAP and TBARS in the GTE-supplemented group (r = − 0.40, p
- Published
- 2018