2,390 results on '"Albers, Gregory W"'
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52. Contributors
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Adams, Harold P., primary, Adeoye, Opeolu, additional, Albers, Gregory W., additional, Alexandrov, Andrei V., additional, Amin-Hanjani, Sepideh, additional, An, Hongyu, additional, Anderson, Craig S., additional, Anrather, Josef, additional, Aparicio, Hugo J., additional, Arai, Ken, additional, Aronowski, Jaroslaw, additional, Atchaneeyasakul, Kunakorn, additional, Audebert, Heinrich, additional, Auer, Roland N., additional, Awad, Issam A., additional, Ay, Hakan, additional, Baltan, Selva, additional, Balu, Ramani, additional, Behbahani, Mandana, additional, Benavente, Oscar R., additional, Bershad, Eric M., additional, Berthaud, Jimmy V., additional, Blackburn, Spiros L., additional, Bonati, Leo H., additional, Bösel, Julian, additional, Bousser, Marie Germaine, additional, Broderick, Joseph P., additional, Brown, Martin M., additional, Brown, Wendy, additional, Brust, John C.M., additional, Bushnell, Cheryl, additional, Canhão, Patrícia, additional, Caplan, Louis R., additional, Carrión-Penagos, Julián, additional, Castellanos, Mar, additional, Caunca, Michelle R., additional, Chabriat, Hugues, additional, Chamorro, Angel, additional, Chen, Jieli, additional, Chen, Jun, additional, Chopp, Michael, additional, Christorforids, Greg, additional, Connolly, E. Sander, additional, Cramer, Steven C., additional, Cucchiara, Brett L., additional, Czap, Alexandra L., additional, Dannenbaum, Mark J., additional, Davis, Patricia H., additional, Dawson, Ted M., additional, Dawson, Valina L., additional, Day, Arthur L., additional, De Silva, T. Michael, additional, de Sousa, Diana Aguiar, additional, Del Brutto, Victor J., additional, del Zoppo, Gregory J., additional, Derdeyn, Colin P., additional, Di Tullio, Marco R., additional, Diener, Hans Christoph, additional, Diringer, Michael N., additional, Dobkin, Bruce H., additional, Dzialowski, Imanuel, additional, Elkind, Mitchell S.V., additional, Elm, Jordan, additional, Feigin, Valery L., additional, Ferro, José Manuel, additional, Field, Thalia S., additional, Fischer, Marlene, additional, Fornage, Myriam, additional, Furie, Karen L., additional, Garcia-Bonilla, Lidia, additional, Giannotta, Steven L., additional, Gobin, Y. Pierre, additional, Goldberg, Mark P., additional, Goldstein, Larry B., additional, Gonzales, Nicole R., additional, Greer, David M., additional, Grotta, James C., additional, Guo, Ruiming, additional, Gutierrez, Jose, additional, Harmel, Peter, additional, Howard, George, additional, Howard, Virginia J., additional, Hwang, Jee-Yeon, additional, Iadecola, Costantino, additional, Jahan, Reza, additional, Jickling, Glen C., additional, Joutel, Anne, additional, Kasner, Scott E., additional, Katan, Mira, additional, Kellner, Christopher P., additional, Khan, Muhib, additional, Kidwell, Chelsea S., additional, Kim, Helen, additional, Kim, Jong S., additional, Kircher, Charles E., additional, Krings, Timo, additional, Krishnamurthi, Rita V., additional, Kurth, Tobias, additional, Lansberg, Maarten G., additional, Levy, Elad I., additional, Liebeskind, David S., additional, Liew, Sook-Lei, additional, Lin, David J., additional, Lisle, Benjamin, additional, Lo, Eng H., additional, Lyden, Patrick D., additional, Maki, Takakuni, additional, Maragkos, Georgios A., additional, Marosfoi, Miklos, additional, McCullough, Louise D., additional, Meckler, Jason M., additional, Meschia, James Frederick, additional, Messé, Steven R., additional, Mocco, J, additional, Mokin, Maxim, additional, Mooney, Michael A., additional, Morgenstern, Lewis B., additional, Moskowitz, Michael A., additional, Mullen, Michael T., additional, Nägel, Steffen, additional, Nedergaard, Maiken, additional, Neira, Justin A., additional, Newman, Sarah, additional, Nicholson, Patrick J., additional, Norrving, Bo, additional, O’Donnell, Martin, additional, Ofengeim, Dimitry, additional, Ogata, Jun, additional, Ogilvy, Christopher S., additional, Orrù, Emanuele, additional, Ortega-Gutiérrez, Santiago, additional, Padrick, Matthew Maximillian, additional, Parsha, Kaushik, additional, Parsons, Mark, additional, Patel, Neil V., additional, Patel, Virendra I., additional, Pawlikowska, Ludmila, additional, Pérez, Adriana, additional, Perez-Pinzon, Miguel A., additional, Picard, John M., additional, Polster, Sean P., additional, Powers, William J., additional, Puetz, Volker, additional, Putaala, Jukka, additional, Rabinovich, Margarita, additional, Ransom, Bruce R., additional, Roa, Jorge A., additional, Rosenberg, Gary A., additional, Rossitto, Christina P., additional, Rundek, Tatjana, additional, Russin, Jonathan J., additional, Sacco, Ralph L., additional, Safouris, Apostolos, additional, Samaniego, Edgar A., additional, Sansing, Lauren H., additional, Satani, Nikunj, additional, Sattenberg, Ronald J., additional, Saver, Jeffrey L., additional, Savitz, Sean I., additional, Schmidt, Christian, additional, Seshadri, Sudha, additional, Sharma, Vijay K., additional, Sharp, Frank R., additional, Sheth, Kevin N., additional, Siddiqi, Omar K., additional, Singhal, Aneesh B., additional, Sobey, Christopher G., additional, Sommer, Clemens J., additional, Spetzler, Robert F., additional, Stapleton, Christopher J., additional, Strickland, Ben A., additional, Su, Hua, additional, Suarez, José I., additional, Takayama, Hiroo, additional, Tarsia, Joseph, additional, Tatlisumak, Turgut, additional, Thomas, Ajith J., additional, Thompson, John W., additional, Tsivgoulis, Georgios, additional, Tournier-Lasserve, Elizabeth, additional, Vidal, Gabriel, additional, Wakhloo, Ajay K., additional, Weksler, Babette B., additional, Willey, Joshua Z., additional, Wintermark, Max, additional, Wong, Lawrence K.S., additional, Xi, Guohua, additional, Xu, Jinchong, additional, Yaghi, Shadi, additional, Yamaguchi, Takenori, additional, Yang, Tuo, additional, Yasaka, Masahiro, additional, Zahuranec, Darin B., additional, Zhang, Feng, additional, Zhang, John H., additional, Zheng, Zhitong, additional, Zukin, R. Suzanne, additional, and Zweifler, Richard M., additional
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- 2022
- Full Text
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53. Cost-Effectiveness of Solitaire Stent Retriever Thrombectomy for Acute Ischemic Stroke
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Shireman, Theresa I, Wang, Kaijun, Saver, Jeffrey L, Goyal, Mayank, Bonafé, Alain, Diener, Hans-Christoph, Levy, Elad I, Pereira, Vitor M, Albers, Gregory W, Cognard, Christophe, Hacke, Werner, Jansen, Olav, Jovin, Tudor G, Mattle, Heinrich P, Nogueira, Raul G, Siddiqui, Adnan H, Yavagal, Dileep R, Devlin, Thomas G, Lopes, Demetrius K, Reddy, Vivek K, du Mesnil de Rochemont, Richard, Jahan, Reza, Vilain, Katherine A, House, John, Lee, Jin-Moo, and Cohen, David J
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Aging ,Clinical Research ,Comparative Effectiveness Research ,Brain Disorders ,Clinical Trials and Supportive Activities ,Cost Effectiveness Research ,Stroke ,Good Health and Well Being ,Aged ,Aged ,80 and over ,Brain Ischemia ,Cohort Studies ,Cost-Benefit Analysis ,Endovascular Procedures ,Equipment Failure ,Female ,Follow-Up Studies ,Hospitalization ,Humans ,Male ,Middle Aged ,Prospective Studies ,Stents ,Thrombectomy ,Treatment Outcome ,quality-adjusted life years ,stents ,stroke ,thrombectomy ,tissue-type plasminogen activator ,SWIFT-PRIME Investigators ,Cardiorespiratory Medicine and Haematology ,Neurosciences ,Neurology & Neurosurgery ,Clinical sciences ,Allied health and rehabilitation science - Abstract
Background and purposeClinical trials have demonstrated improved 90-day outcomes for patients with acute ischemic stroke treated with stent retriever thrombectomy plus tissue-type plasminogen activator (SST+tPA) compared with tPA. Previous studies suggested that this strategy may be cost-effective, but models were derived from pooled data and older assumptions.MethodsIn this prospective economic substudy conducted alongside the SWIFT-PRIME trial (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke), in-trial costs were measured for patients using detailed medical resource utilization and hospital billing data. Utility weights were assessed at 30 and 90 days using the EuroQol-5 dimension questionnaire. Post-trial costs and life-expectancy were estimated for each surviving patient using a model based on trial data and inputs derived from a contemporary cohort of ischemic stroke survivors.ResultsIndex hospitalization costs were $17 183 per patient higher for SST+tPA than for tPA ($45 761 versus $28 578; P
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- 2017
54. Effect of Sex on Clinical Outcome and Imaging after Endovascular Treatment of Large-Vessel Ischemic Stroke
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Demeestere, Jelle, Christensen, Sören, Mlynash, Michael, Federau, Christian, Albers, Gregory W., Lemmens, Robin, and Lansberg, Maarten G.
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- 2021
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55. The Effect of Hyperglycemia on Infarct Growth after Reperfusion: An Analysis of the DEFUSE 3 trial
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Yaghi, Shadi, Dehkharghani, Seena, Raz, Eytan, Jayaraman, Mahesh, Tanweer, Omar, Grory, Brian Mac, Henninger, Nils, Lansberg, Maarten G., Albers, Gregory W., and Havenon, Adam de
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- 2021
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56. Intravenous tPA (Tissue-Type Plasminogen Activator) Correlates With Favorable Venous Outflow Profiles in Acute Ischemic Stroke
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Faizy, Tobias D., Mlynash, Michael, Marks, Michael P., Christensen, Soren, Kabiri, Reza, Kuraitis, Gabriella M., Broocks, Gabriel, Winkelmeier, Laurens, Geest, Vincent, Nawabi, Jawed, Lansberg, Maarten G., Albers, Gregory W., Fiehler, Jens, Wintermark, Max, and Heit, Jeremy J.
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- 2022
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57. Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data
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Berkhemer, Olvert A, Fransen, Puck SS, Beumer, Debbie, van den Berg, Lucie A, Lingsma, Hester F, Yoo, Albert J, Schonewille, Wouter J, Vos, Jan Albert, Nederkoorn, Paul J, Wermer, Marieke JH, van Walderveen, Marianne AA, Staals, Julie, Hofmeijer, Jeannette, van Oostayen, Jacques A., Lycklama à Nijeholt, Geert J., Boiten, Jelis, Brouwer, Patrick A., Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., Kappelle, Jaap, Lo, Rob H, van Dijk, Ewoud J., de Vries, Joost, de Kort, Paul L.M., van Rooij, Willem Jan J., van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Visser, Marieke C., Bot, Joseph C.J., Vroomen, Patrick C., Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Tielbeek, Alexander V., den Hertog, Heleen M., Gerrits, Dick G., van den Berg-Vos, Renske M., Karas, Giorgos B., Steyerberg, Ewout W., Flach, Zwenneke, Marquering, Henk A., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., Beenen, Ludo F.M., van den Berg, René, Koudstaal, Peter J., van Zwam, Wim H., Roos, Yvo B.W.E.M., van der Lugt, Aad, van Oostenbrugge, Robert J., Majoie, Charles B.L.M., Dippel, Diederik W.J., Brown, Martin M., Liebig, Thomas, Stijnen, Theo, Andersson, Tommy, Mattle, Heinrich, Wahlgren, Nils, van der Heijden, Esther, Ghannouti, Naziha, Fleitour, Nadine, Hooijenga, Imke, Puppels, Corina, Pellikaan, Wilma, Geerling, Annet, Lindl-Velema, Annemieke, van Vemde, Gina, de Ridder, Ans, Greebe, Paut, de Bont-Stikkelbroeck, José, de Meris, Joke, Janssen, Kirsten, Struijk, Willy, Licher, Silvan, Boodt, Nikki, Ros, Adriaan, Venema, Esmee, Slokkers, Ilse, Ganpat, Raymie-Jayce, Mulder, Maxim, Saiedie, Nawid, Heshmatollah, Alis, Schipperen, Stefanie, Vinken, Stefan, van Boxtel, Tiemen, Koets, Jeroen, Boers, Merel, Santos, Emilie, Borst, Jordi, Jansen, Ivo, Kappelhof, Manon, Lucas, Marit, Geuskens, Ralph, Barros, Renan Sales, Dobbe, Roeland, Csizmadia, Marloes, Hill, MD, Goyal, M, Demchuk, AM, Menon, BK, Eesa, M, Ryckborst, KJ, Wright, MR, Kamal, NR, Andersen, L, Randhawa, PA, Stewart, T, Patil, S, Minhas, P, Almekhlafi, M, Mishra, S, Clement, F, Sajobi, T, Shuaib, A, Montanera, WJ, Roy, D, Silver, FL, Jovin, TG, Frei, DF, Sapkota, B, Rempel, JL, Thornton, J, Williams, D, Tampieri, D, Poppe, AY, Dowlatshahi, D, Wong, JH, Mitha, AP, Subramaniam, S, Hull, G, Lowerison, MW, Salluzzi, M, Maxwell, M, Lacusta, S, Drupals, E, Armitage, K, Barber, PA, Smith, EE, Morrish, WF, Coutts, SB, Derdeyn, C, Demaerschalk, B, Yavagal, D, Martin, R, Brant, R, Yu, Y, Willinsky, RA, Weill, A, Kenney, C, Aram, H, Stys, PK, Watson, TW, Klein, G, Pearson, D, Couillard, P, Trivedi, A, Singh, D, Klourfeld, E, Imoukhuede, O, Nikneshan, D, Blayney, S, Reddy, R, Choi, P, Horton, M, Musuka, T, Dubuc, V, Field, TS, Desai, J, Adatia, S, Alseraya, A, Nambiar, V, van Dijk, R, Newcommon, NJ, Schwindt, B, Butcher, KS, Jeerakathil, T, Buck, B, Khan, K, Naik, SS, Emery, DJ, Owen, RJ, Kotylak, TB, Ashforth, RA, Yeo, TA, McNally, D, Siddiqui, M, Saqqur, M, Hussain, D, Kalashyan, H, Manosalva, A, Kate, M, Gioia, L, Hasan, S, Mohammad, A, Muratoglu, M, Cullen, A, Brennan, P, O'Hare, A, Looby, S, Hyland, D, Duff, S, McCusker, M, Hallinan, B, Lee, S, McCormack, J, Moore, A, O'Connor, M, Donegan, C, Brewer, L, Martin, A, Murphy, S, O'Rourke, K, Smyth, S, Kelly, P, Lynch, T, Daly, T, O'Brien, P, O'Driscoll, A, Martin, M, Collins, R, Coughlan, T, McCabe, D, O'Neill, D, Mulroy, M, Lynch, O, Walsh, T, O'Donnell, M, Galvin, T, Harbison, J, McElwaine, P, Mulpeter, K, McLoughlin, C, Reardon, M, Harkin, E, Dolan, E, Watts, M, Cunningham, N, Fallon, C, Gallagher, S, Cotter, P, Crowe, M, Doyle, R, Noone, I, Lapierre, M, Coté, VA, Lanthier, S, Odier, C, Durocher, A, Raymond, J, Daneault, N, Deschaintre, Y, Jankowitz, B, Baxendell, L, Massaro, L, Jackson-Graves, C, Decesare, S, Porter, P, Armbruster, K, Adams, A, Billigan, J, Oakley, J, Ducruet, A, Jadhav, A, Giurgiutiu, D-V, Aghaebrahim, A, Reddy, V, Hammer, M, Starr, M, Totoraitis, V, Wechsler, L, Streib, S, Rangaraju, S, Campbell, D, Rocha, M, Gulati, D, Krings, T, Kalman, L, Cayley, A, Williams, J, Wiegner, R, Casaubon, LK, Jaigobin, C, del Campo, JM, Elamin, E, Schaafsma, JD, Agid, R, Farb, R, ter Brugge, K, Sapkoda, BL, Baxter, BW, Barton, K, Knox, A, Porter, A, Sirelkhatim, A, Devlin, T, Dellinger, C, Pitiyanuvath, N, Patterson, J, Nichols, J, Quarfordt, S, Calvert, J, Hawk, H, Fanale, C, Bitner, A, Novak, A, Huddle, D, Bellon, R, Loy, D, Wagner, J, Chang, I, Lampe, E, Spencer, B, Pratt, R, Bartt, R, Shine, S, Dooley, G, Nguyen, T, Whaley, M, McCarthy, K, Teitelbaum, J, Poon, W, Campbell, N, Cortes, M, Lum, C, Shamloul, R, Robert, S, Stotts, G, Shamy, M, Steffenhagen, N, Blacquiere, D, Hogan, M, AlHazzaa, M, Basir, G, Lesiuk, H, Iancu, D, Santos, M, Choe, H, Weisman, DC, Jonczak, K, Blue-Schaller, A, Shah, Q, MacKenzie, L, Klein, B, Kulandaivel, K, Kozak, O, Gzesh, DJ, Harris, LJ, Khoury, JS, Mandzia, J, Pelz, D, Crann, S, Fleming, L, Hesser, K, Beauchamp, B, Amato-Marzialli, B, Boulton, M, Lopez-Ojeda, P, Sharma, M, Lownie, S, Chan, R, Swartz, R, Howard, P, Golob, D, Gladstone, D, Boyle, K, Boulos, M, Hopyan, J, Yang, V, Da Costa, L, Holmstedt, CA, Turk, AS, Navarro, R, Jauch, E, Ozark, S, Turner, R, Phillips, S, Shankar, J, Jarrett, J, Gubitz, G, Maloney, W, Vandorpe, R, Schmidt, M, Heidenreich, J, Hunter, G, Kelly, M, Whelan, R, Peeling, L, Burns, PA, Hunter, A, Wiggam, I, Kerr, E, Watt, M, Fulton, A, Gordon, P, Rennie, I, Flynn, P, Smyth, G, O'Leary, S, Gentile, N, Linares, G, McNelis, P, Erkmen, K, Katz, P, Azizi, A, Weaver, M, Jungreis, C, Faro, S, Shah, P, Reimer, H, Kalugdan, V, Saposnik, G, Bharatha, A, Li, Y, Kostyrko, P, Marotta, T, Montanera, W, Sarma, D, Selchen, D, Spears, J, Heo, JH, Jeong, K, Kim, DJ, Kim, BM, Kim, YD, Song, D, Lee, K-J, Yoo, J, Bang, OY, Rho, S, Lee, J, Jeon, P, Kim, KH, Cha, J, Kim, SJ, Ryoo, S, Lee, MJ, Sohn, S-I, Kim, C-H, Ryu, H-G, Hong, J-H, Chang, H-W, Lee, C-Y, Rha, J, Davis, Stephen M, Donnan, Geoffrey A, Campbell, Bruce CV, Mitchell, Peter J, Churilov, Leonid, Yan, Bernard, Dowling, Richard, Yassi, Nawaf, Oxley, Thomas J, Wu, Teddy Y, Silver, Gabriel, McDonald, Amy, McCoy, Rachael, Kleinig, Timothy J, Scroop, Rebecca, Dewey, Helen M, Simpson, Marion, Brooks, Mark, Coulton, Bronwyn, Krause, Martin, Harrington, Timothy J, Steinfort, Brendan, Faulder, Kenneth, Priglinger, Miriam, Day, Susan, Phan, Thanh, Chong, Winston, Holt, Michael, Chandra, Ronil V, Ma, Henry, Young, Dennis, Wong, Kitty, Wijeratne, Tissa, Tu, Hans, Mackay, Elizabeth, Celestino, Sherisse, Bladin, Christopher F, Loh, Poh Sien, Gilligan, Amanda, Ross, Zofia, Coote, Skye, Frost, Tanya, Parsons, Mark W, Miteff, Ferdinand, Levi, Christopher R, Ang, Timothy, Spratt, Neil, Kaauwai, Lara, Badve, Monica, Rice, Henry, de Villiers, Laetitia, Barber, P. Alan, McGuinness, Ben, Hope, Ayton, Moriarty, Maurice, Bennett, Patricia, Wong, Andrew, Coulthard, Alan, Lee, Andrew, Jannes, Jim, Field, Deborah, Sharma, Gagan, Salinas, Simon, Cowley, Elise, Snow, Barry, Kolbe, John, Stark, Richard, King, John, Macdonnell, Richard, Attia, John, D'Este, Cate, Saver, Jeffrey L, Goyal, Mayank, Diener, Hans-Christoph, Levy, Elad I., Bonafé, Alain, Mendes Pereira, Vitor, Jahan, Reza, Albers, Gregory W., Cognard, Christophe, Cohen, David J., Hacke, Werner, Jansen, Olav, Jovin, Tudor G., Mattle, Heinrich P., Nogueira, Raul G., Siddiqui, Adnan H., Yavagal, Dileep R., von Kummer, Rüdiger, Smith, Wade, Turjman, Francis, Hamilton, Scott, Chiacchierini, Richard, Amar, Arun, Sanossian, Nerses, Loh, Yince, Baxter, B, Reddy, VK, Horev, A, Star, M, Siddiqui, A, Hopkins, LN, Snyder, K, Sawyer, R, Hall, S, Costalat, V, Riquelme, C, Machi, P, Omer, E, Arquizan, C, Mourand, I, Charif, M, Ayrignac, X, Menjot de Champfleur, N, Leboucq, N, Gascou, G, Moynier, M, du Mesnil de Rochemont, R, Singer, O, Berkefeld, J, Foerch, C, Lorenz, M, Pfeilschifer, W, Hattingen, E, Wagner, M, You, SJ, Lescher, S, Braun, H, Dehkharghani, S, Belagaje, SR, Anderson, A, Lima, A, Obideen, M, Haussen, D, Dharia, R, Frankel, M, Patel, V, Owada, K, Saad, A, Amerson, L, Horn, C, Doppelheuer, S, Schindler, K, Lopes, DK, Chen, M, Moftakhar, R, Anton, C, Smreczak, M, Carpenter, JS, Boo, S, Rai, A, Roberts, T, Tarabishy, A, Gutmann, L, Brooks, C, Brick, J, Domico, J, Reimann, G, Hinrichs, K, Becker, M, Heiss, E, Selle, C, Witteler, A, Al-Boutros, S, Danch, M-J, Ranft, A, Rohde, S, Burg, K, Weimar, C, Zegarac, V, Hartmann, C, Schlamann, M, Göricke, S, Ringlestein, A, Wanke, I, Mönninghoff, C, Dietzold, M, Budzik, R, Davis, T, Eubank, G, Hicks, WJ, Pema, P, Vora, N, Mejilla, J, Taylor, M, Clark, W, Rontal, A, Fields, J, Peterson, B, Nesbit, G, Lutsep, H, Bozorgchami, H, Priest, R, Ologuntoye, O, Barnwell, S, Dogan, A, Herrick, K, Takahasi, C, Beadell, N, Brown, B, Jamieson, S, Hussain, MS, Russman, A, Hui, F, Wisco, D, Uchino, K, Khawaja, Z, Katzan, I, Toth, G, Cheng-Ching, E, Bain, M, Man, S, Farrag, A, George, P, John, S, Shankar, L, Drofa, A, Dahlgren, R, Bauer, A, Itreat, A, Taqui, A, Cerejo, R, Richmond, A, Ringleb, P, Bendszus, M, Möhlenbruch, M, Reiff, T, Amiri, H, Purrucker, J, Herweh, C, Pham, M, Menn, O, Ludwig, I, Acosta, I, Villar, C, Morgan, W, Sombutmai, C, Hellinger, F, Allen, E, Bellew, M, Gandhi, R, Bonwit, E, Aly, J, Ecker, RD, Seder, D, Morris, J, Skaletsky, M, Belden, J, Baker, C, Connolly, LS, Papanagiotou, P, Roth, C, Kastrup, A, Politi, M, Brunner, F, Alexandrou, M, Merdivan, H, Ramsey, C, Given II, C, Renfrow, S, Deshmukh, V, Sasadeusz, K, Vincent, F, Thiesing, JT, Putnam, J, Bhatt, A, Kansara, A, Caceves, D, Lowenkopf, T, Yanase, L, Zurasky, J, Dancer, S, Freeman, B, Scheibe-Mirek, T, Robison, J, Roll, J, Clark, D, Rodriguez, M, Fitzsimmons, B-FM, Zaidat, O, Lynch, JR, Lazzaro, M, Larson, T, Padmore, L, Das, E, Farrow-Schmidt, A, Hassan, A, Tekle, W, Cate, C, Jansen, O, Cnyrim, C, Wodarg, F, Wiese, C, Binder, A, Riedel, C, Rohr, A, Lang, N, Laufs, H, Krieter, S, Remonda, L, Diepers, M, Añon, J, Nedeltchev, K, Kahles, T, Biethahn, S, Lindner, M, Chang, V, Gächter, C, Esperon, C, Guglielmetti, M, Arenillas Lara, JF, Martínez Galdámez, M, Calleja Sanz, AI, Cortijo Garcia, E, Garcia Bermejo, P, Perez, S, Mulero Carrillo, P, Crespo Vallejo, E, Ruiz Piñero, M, Lopez Mesonero, L, Reyes Muñoz, FJ, Brekenfeld, C, Buhk, J-H, Krützelmann, A, Thomalla, G, Cheng, B, Beck, C, Hoppe, J, Goebell, E, Holst, B, Grzyska, U, Wortmann, G, Starkman, S, Duckwiler, G, Jahan, R, Rao, N, Sheth, S, Ng, K, Noorian, A, Szeder, V, Nour, M, McManus, M, Huang, J, Tarpley, J, Tateshima, S, Gonzalez, N, Ali, L, Liebeskind, D, Hinman, J, Calderon-Arnulphi, M, Liang, C, Guzy, J, Koch, S, DeSousa, K, Gordon-Perue, G, Elhammady, M, Peterson, E, Pandey, V, Dharmadhikari, S, Khandelwal, P, Malik, A, Pafford, R, Gonzalez, P, Ramdas, K, Andersen, G, Damgaard, D, Von Weitzel-Mudersbach, P, Simonsen, C, Ruiz de Morales Ayudarte, N, Poulsen, M, Sørensen, L, Karabegovich, S, Hjørringgaard, M, Hjort, N, Harbo, T, Sørensen, K, Deshaies, E, Padalino, D, Swarnkar, A, Latorre, JG, Elnour, E, El-Zammar, Z, Villwock, M, Farid, H, Balgude, A, Cross, L, Hansen, K, Holtmannspötter, M, Kondziella, D, Hoejgaard, J, Taudorf, S, Soendergaard, H, Wagner, A, Cronquist, M, Stavngaard, T, Cortsen, M, Krarup, LH, Hyldal, T, Haring, H-P, Guggenberger, S, Hamberger, M, Trenkler, J, Sonnberger, M, Nussbaumer, K, Dominger, C, Bach, E, Jagadeesan, BD, Taylor, R, Kim, J, Shea, K, Tummala, R, Zacharatos, H, Sandhu, D, Ezzeddine, M, Grande, A, Hildebrandt, D, Miller, K, Scherber, J, Hendrickson, A, Jumaa, M, Zaidi, S, Hendrickson, T, Snyder, V, Killer-Oberpfalzer, M, Mutzenbach, J, Weymayr, F, Broussalis, E, Stadler, K, Jedlitschka, A, Malek, A, Mueller-Kronast, N, Beck, P, Martin, C, Summers, D, Day, J, Bettinger, I, Holloway, W, Olds, K, Arkin, S, Akhtar, N, 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Ajlan, Fahad S, Reddy, Vivek, Dowlatshahi, Dar, Sourour, Nader-Antoine, Oppenheim, Catherine, Mitha, Alim P, Weimar, Christian, van Oostenbrugge, Robert J, Cobo, Erik, Demchuk, Andrew M, Boers, Anna M M, Ford, Gary A, Brown, B Scott, Jovin, Tudor, van Zwam, Wim H, Hill, Michael D, White, Phil, and Bracard, Serge
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58. Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data
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Berkhemer, Olvert A, Fransen, Puck SS, Beumer, Debbie, van den Berg, Lucie A, Lingsma, Hester F, Yoo, Albert J, Schonewille, Wouter J, Vos, Jan Albert, Nederkoorn, Paul J, Wermer, Marieke JH, van Walderveen, Marianne AA, Staals, Julie, Hofmeijer, Jeannette, van Oostayen, Jacques A., Lycklama à Nijeholt, Geert J., Boiten, Jelis, Brouwer, Patrick A., Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., Kappelle, Jaap, Lo, Rob H, van Dijk, Ewoud J., de Vries, Joost, de Kort, Paul L.M., van Rooij, Willem Jan J., van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Visser, Marieke C., Bot, Joseph C.J., Vroomen, Patrick C., Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Tielbeek, Alexander V., den Hertog, Heleen M., Gerrits, Dick G., van den Berg-Vos, Renske M., Karas, Giorgos B., Steyerberg, Ewout W., Flach, Zwenneke, Marquering, Henk A., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., Beenen, Ludo F.M., van den Berg, René, Koudstaal, Peter J., van Zwam, Wim H., Roos, Yvo B.W.E.M., van der Lugt, Aad, van Oostenbrugge, Robert J., Majoie, Charles B.L.M., Dippel, Diederik W.J., Brown, Martin M., Liebig, Thomas, Stijnen, Theo, Andersson, Tommy, Mattle, Heinrich, Wahlgren, Nils, van der Heijden, Esther, Ghannouti, Naziha, Fleitour, Nadine, Hooijenga, Imke, Puppels, Corina, Pellikaan, Wilma, Geerling, Annet, Lindl-Velema, Annemieke, van Vemde, Gina, de Ridder, Ans, Greebe, Paut, de Bont-Stikkelbroeck, José, de Meris, Joke, Janssen, Kirsten, Struijk, Willy, Licher, Silvan, Boodt, Nikki, Ros, Adriaan, Venema, Esmee, Slokkers, Ilse, Ganpat, Raymie-Jayce, Mulder, Maxim, Saiedie, Nawid, Heshmatollah, Alis, Schipperen, Stefanie, Vinken, Stefan, van Boxtel, Tiemen, Koets, Jeroen, Boers, Merel, Santos, Emilie, Borst, Jordi, Jansen, Ivo, Kappelhof, Manon, Lucas, Marit, Geuskens, Ralph, Barros, Renan Sales, Dobbe, Roeland, Csizmadia, Marloes, Hill, MD, Goyal, M, Demchuk, AM, Menon, BK, Eesa, M, Ryckborst, KJ, 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de Rochemont, R, Singer, O, Berkefeld, J, Foerch, C, Lorenz, M, Pfeilschifer, W, Hattingen, E, Wagner, M, You, SJ, Lescher, S, Braun, H, Dehkharghani, S, Belagaje, SR, Anderson, A, Lima, A, Obideen, M, Haussen, D, Dharia, R, Frankel, M, Patel, V, Owada, K, Saad, A, Amerson, L, Horn, C, Doppelheuer, S, Schindler, K, Lopes, DK, Chen, M, Moftakhar, R, Anton, C, Smreczak, M, Carpenter, JS, Boo, S, Rai, A, Roberts, T, Tarabishy, A, Gutmann, L, Brooks, C, Brick, J, Domico, J, Reimann, G, Hinrichs, K, Becker, M, Heiss, E, Selle, C, Witteler, A, Al-Boutros, S, Danch, M-J, Ranft, A, Rohde, S, Burg, K, Weimar, C, Zegarac, V, Hartmann, C, Schlamann, M, Göricke, S, Ringlestein, A, Wanke, I, Mönninghoff, C, Dietzold, M, Budzik, R, Davis, T, Eubank, G, Hicks, WJ, Pema, P, Vora, N, Mejilla, J, Taylor, M, Clark, W, Rontal, A, Fields, J, Peterson, B, Nesbit, G, Lutsep, H, Bozorgchami, H, Priest, R, Ologuntoye, O, Barnwell, S, Dogan, A, Herrick, K, Takahasi, C, Beadell, N, Brown, B, Jamieson, S, Hussain, MS, Russman, A, Hui, F, Wisco, D, Uchino, K, Khawaja, Z, Katzan, I, Toth, G, Cheng-Ching, E, Bain, M, Man, S, Farrag, A, George, P, John, S, Shankar, L, Drofa, A, Dahlgren, R, Bauer, A, Itreat, A, Taqui, A, Cerejo, R, Richmond, A, Ringleb, P, Bendszus, M, Möhlenbruch, M, Reiff, T, Amiri, H, Purrucker, J, Herweh, C, Pham, M, Menn, O, Ludwig, I, Acosta, I, Villar, C, Morgan, W, Sombutmai, C, Hellinger, F, Allen, E, Bellew, M, Gandhi, R, Bonwit, E, Aly, J, Ecker, RD, Seder, D, Morris, J, Skaletsky, M, Belden, J, Baker, C, Connolly, LS, Papanagiotou, P, Roth, C, Kastrup, A, Politi, M, Brunner, F, Alexandrou, M, Merdivan, H, Ramsey, C, Given II, C, Renfrow, S, Deshmukh, V, Sasadeusz, K, Vincent, F, Thiesing, JT, Putnam, J, Bhatt, A, Kansara, A, Caceves, D, Lowenkopf, T, Yanase, L, Zurasky, J, Dancer, S, Freeman, B, Scheibe-Mirek, T, Robison, J, Roll, J, Clark, D, Rodriguez, M, Fitzsimmons, B-FM, Zaidat, O, Lynch, JR, Lazzaro, M, Larson, T, Padmore, L, Das, E, Farrow-Schmidt, A, Hassan, A, Tekle, W, Cate, C, Jansen, O, Cnyrim, C, Wodarg, F, Wiese, C, Binder, A, Riedel, C, Rohr, A, Lang, N, Laufs, H, Krieter, S, Remonda, L, Diepers, M, Añon, J, Nedeltchev, K, Kahles, T, Biethahn, S, Lindner, M, Chang, V, Gächter, C, Esperon, C, Guglielmetti, M, Arenillas Lara, JF, Martínez Galdámez, M, Calleja Sanz, AI, Cortijo Garcia, E, Garcia Bermejo, P, Perez, S, Mulero Carrillo, P, Crespo Vallejo, E, Ruiz Piñero, M, Lopez Mesonero, L, Reyes Muñoz, FJ, Brekenfeld, C, Buhk, J-H, Krützelmann, A, Thomalla, G, Cheng, B, Beck, C, Hoppe, J, Goebell, E, Holst, B, Grzyska, U, Wortmann, G, Starkman, S, Duckwiler, G, Jahan, R, Rao, N, Sheth, S, Ng, K, Noorian, A, Szeder, V, Nour, M, McManus, M, Huang, J, Tarpley, J, Tateshima, S, Gonzalez, N, Ali, L, Liebeskind, D, Hinman, J, Calderon-Arnulphi, M, Liang, C, Guzy, J, Koch, S, DeSousa, K, Gordon-Perue, G, Elhammady, M, Peterson, E, Pandey, V, Dharmadhikari, S, Khandelwal, P, Malik, A, Pafford, R, Gonzalez, P, Ramdas, K, Andersen, G, Damgaard, D, Von Weitzel-Mudersbach, P, Simonsen, C, Ruiz de Morales Ayudarte, N, Poulsen, M, Sørensen, L, Karabegovich, S, Hjørringgaard, M, Hjort, N, Harbo, T, Sørensen, K, Deshaies, E, Padalino, D, Swarnkar, A, Latorre, JG, Elnour, E, El-Zammar, Z, Villwock, M, Farid, H, Balgude, A, Cross, L, Hansen, K, Holtmannspötter, M, Kondziella, D, Hoejgaard, J, Taudorf, S, Soendergaard, H, Wagner, A, Cronquist, M, Stavngaard, T, Cortsen, M, Krarup, LH, Hyldal, T, Haring, H-P, Guggenberger, S, Hamberger, M, Trenkler, J, Sonnberger, M, Nussbaumer, K, Dominger, C, Bach, E, Jagadeesan, BD, Taylor, R, Kim, J, Shea, K, Tummala, R, Zacharatos, H, Sandhu, D, Ezzeddine, M, Grande, A, Hildebrandt, D, Miller, K, Scherber, J, Hendrickson, A, Jumaa, M, Zaidi, S, Hendrickson, T, Snyder, V, Killer-Oberpfalzer, M, Mutzenbach, J, Weymayr, F, Broussalis, E, Stadler, K, Jedlitschka, A, Malek, A, Mueller-Kronast, N, Beck, P, Martin, C, Summers, D, Day, J, Bettinger, I, Holloway, W, Olds, K, Arkin, S, Akhtar, N, Boutwell, C, Crandall, S, Schwartzman, M, Weinstein, C, Brion, B, Prothmann, S, Kleine, J, Kreiser, K, Boeckh-Behrens, T, Poppert, H, Wunderlich, S, Koch, ML, Biberacher, V, Huberle, A, Gora-Stahlberg, G, Knier, B, Meindl, T, Utpadel-Fischler, D, Zech, M, Kowarik, M, Seifert, C, Schwaiger, B, Puri, A, Hou, S, Wakhloo, A, Moonis, M, Henninger, N, Goddeau, R, Massari, F, Minaeian, A, Lozano, JD, Ramzan, M, Stout, C, Patel, A, Tunguturi, A, Onteddu, S, Carandang, R, Howk, M, Ribó, M, Sanjuan, E, Rubiera, M, Pagola, J, Flores, A, Muchada, M, Meler, P, Huerga, E, Gelabert, S, Coscojuela, P, Tomasello, A, Rodriguez, D, Santamarina, E, Maisterra, O, Boned, S, Seró, L, Rovira, A, Molina, CA, Millán, M, Muñoz, L, Pérez de la Ossa, N, Gomis, M, Dorado, L, López-Cancio, E, Palomeras, E, Munuera, J, García Bermejo, P, Remollo, S, Castaño, C, García-Sort, R, Cuadras, P, Puyalto, P, Hernández-Pérez, M, Jiménez, M, Martínez-Piñeiro, A, Lucente, G, Dávalos, A, Chamorro, A, Urra, X, Obach, V, Cervera, A, Amaro, S, Llull, L, Codas, J, Balasa, M, Navarro, J, Ariño, H, Aceituno, A, Rudilosso, S, Renu, A, Macho, JM, San Roman, L, Blasco, J, López, A, Macías, N, Cardona, P, Quesada, H, Rubio, F, Cano, L, Lara, B, de Miquel, MA, Aja, L, Serena, J, Cobo, E, Albers, Gregory W, Lees, Kennedy R, Arenillas, J, Roberts, R, Al-Ajlan, F, Zimmel, L, Patel, S, Martí-Fàbregas, J, Salvat-Plana, M, Bracard, S, Ducrocq, Xavier, Anxionnat, René, Baillot, Pierre-Alexandre, Barbier, Charlotte, Derelle, Anne-Laure, Lacour, Jean-Christophe, Richard, Sébastien, Samson, Yves, Sourour, Nader, Baronnet-Chauvet, Flore, Clarencon, Frédéric, Crozier, Sophie, Deltour, Sandrine, Di Maria, Federico, Le Bouc, Raphael, Leger, Anne, Mutlu, Gurkan, Rosso, Charlotte, Szatmary, Zoltan, Yger, Marion, Zavanone, Chiara, Bakchine, Serge, Pierot, Laurent, Caucheteux, Nathalie, Estrade, Laurent, Kadziolka, Krzysztof, Leautaud, Alexandre, Renkes, Céline, Serre, Isabelle, Desal, Hubert, Guillon, Benoît, Boutoleau-Bretonniere, Claire, Daumas-Duport, Benjamin, De Gaalon, Solène, Derkinderen, Pascal, Evain, Sarah, Herisson, Fanny, Laplaud, David-Axel, Lebouvier, Thibaud, Lintia-Gaultier, Alina, Pouclet-Courtemanche, Hélène, Rouaud, Tiphaine, Rouaud Jaffrenou, Violaine, Schunck, Aurélia, Sevin-Allouet, Mathieu, Toulgoat, Frederique, Wiertlewski, Sandrine, Gauvrit, Jean-Yves, Ronziere, Thomas, Cahagne, Vincent, Ferre, Jean-Christophe, Pinel, Jean-François, Raoult, Hélène, Mas, Jean-Louis, Meder, Jean-François, Al Najjar-Carpentier, Amen-Adam, Birchenall, Julia, Bodiguel, Eric, Calvet, David, Domigo, Valérie, Godon-Hardy, Sylvie, Guiraud, Vincent, Lamy, Catherine, Majhadi, Loubna, Morin, Ludovic, Naggara, Olivier, Trystram, Denis, Turc, Guillaume, Berge, Jérôme, Sibon, Igor, Menegon, Patrice, Barreau, Xavier, Rouanet, François, Debruxelles, Sabrina, Kazadi, Annabelle, Renou, Pauline, Fleury, Olivier, Pasco-Papon, Anne, Dubas, Frédéric, Caroff, Jildaz, Godard Ducceschi, Sophie, Hamon, Marie-Aurélie, Lecluse, Alderic, Marc, Guillaume, Giroud, Maurice, Ricolfi, Frédéric, Bejot, Yannick, Chavent, Adrien, Gentil, Arnaud, Kazemi, Apolline, Osseby, Guy-Victor, Voguet, Charlotte, Mahagne, Marie-Hélène, Sedat, Jacques, Chau, Yves, Suissa, Laurent, Lachaud, Sylvain, Houdart, Emmanuel, Stapf, Christian, Buffon Porcher, Frédérique, Chabriat, Hugues, Guedin, Pierre, Herve, Dominique, Jouvent, Eric, Mawet, Jérôme, Saint-Maurice, Jean-Pierre, Schneble, Hans-Martin, Nighoghossian, Norbert, Berhoune, Nadia-Nawel, Bouhour, Françoise, Cho, Tae-Hee, Derex, Laurent, Felix, Sandra, Gervais-Bernard, Hélène, Gory, Benjamin, Manera, Luis, Mechtouff, Laura, Ritzenthaler, Thomas, Riva, Roberto, Salaris Silvio, Fabrizio, Tilikete, Caroline, Blanc, Raphael, Obadia, Michaël, Bartolini, Mario Bruno, Gueguen, Antoine, Piotin, Michel, Pistocchi, Silvia, Redjem, Hocine, Drouineau, Jacques, Neau, Jean-Philippe, Godeneche, Gaelle, Lamy, Matthias, Marsac, Emilia, Velasco, Stephane, Clavelou, Pierre, Chabert, Emmanuel, Bourgois, Nathalie, Cornut-Chauvinc, Catherine, Ferrier, Anna, Gabrillargues, Jean, Jean, Betty, Marques, Anna-Raquel, Vitello, Nicolas, Detante, Olivier, Barbieux, Marianne, Boubagra, Kamel, Favre Wiki, Isabelle, Garambois, Katia, Tahon, Florence, Ashok, Vasdev, Coskun, Oguzhan, Rodesch, Georges, Lapergue, Bertrand, Bourdain, Frédéric, Evrard, Serge, Graveleau, Philippe, Decroix, Jean Pierre, Wang, Adrien, Sellal, François, Ahle, Guido, Carelli, Gabriela, Dugay, Marie-Hélène, Gaultier, Claude, Lebedinsky, Ariel Pablo, Lita, Lavinia, Musacchio, Raul Mariano, Renglewicz-Destuynder, Catherine, Tournade, Alain, Vuillemet, Françis, Montoro, Francisco Macian, Mounayer, Charbel, Faugeras, Frederic, Gimenez, Laetitia, Labach, Catherine, Lautrette, Géraldine, Denier, Christian, Saliou, Guillaume, Chassin, Olivier, Dussaule, Claire, Melki, Elsa, Ozanne, Augustin, Puccinelli, Francesco, Sachet, Marina, Sarov, Mariana, Bonneville, Jean-François, Moulin, Thierry, Biondi, Alessandra, De Bustos Medeiros, Elisabeth, Vuillier, Fabrice, Courtheoux, Patrick, Viader, Fausto, Apoil-Brissard, Marion, Bataille, Mathieu, Bonnet, Anne-Laure, Cogez, Julien, Touze, Emmanuel, Leclerc, Xavier, Leys, Didier, Aggour, Mohamed, Aguettaz, Pierre, Bodenant, Marie, Cordonnier, Charlotte, Deplanque, Dominique, Girot, Marie, Henon, Hilde, Kalsoum, Erwah, Lucas, Christian, Pruvo, Jean-Pierre, Zuniga, Paolo, Arquizan, Caroline, Costalat, Vincent, Machi, Paolo, Mourand, Isabelle, Riquelme, Carlos, Bounolleau, Pierre, Arteaga, Charles, Faivre, Anthony, Bintner, Marc, Tournebize, Patrice, Charlin, Cyril, Darcel, Françoise, Gauthier-Lasalarie, Pascale, Jeremenko, Marcia, Mouton, Servane, Zerlauth, Jean-Baptiste, Lamy, Chantal, Hervé, Deramond, Hassan, Hosseini, Gaston, André, Barral, Francis-Guy, Garnier, Pierre, Beaujeux, Rémy, Wolff, Valérie, Herbreteau, Denis, Debiais, Séverine, Murray, Alicia, Ford, Gary, Muir, Keith W, White, Philip, Brown, Martin M, Clifton, Andy, Freeman, Janet, Ford, Ian, Markus, Hugh, Wardlaw, Joanna, Molyneux, Andy, Robinson, Thompson, Lewis, Steff, Norrie, John, Robertson, Fergus, Perry, Richard, Dixit, Anand, Cloud, Geoffrey, Clifton, Andrew, Madigan, Jeremy, Roffe, Christine, Nayak, Sanjeev, Lobotesis, Kyriakos, Smith, Craig, Herwadkar, Amit, Kandasamy, Naga, Goddard, Tony, Bamford, John, Subramanian, Ganesh, Lenthall, Rob, Littleton, Edward, Lamin, Sal, Storey, Kelley, Ghatala, Rita, Banaras, Azra, Aeron-Thomas, John, Hazel, Bath, Maguire, Holly, Veraque, Emelda, Harrison, Louise, Keshvara, Rekha, Cunningham, James, Campbell, Bruce C V, van Zwam, Wim H, Menon, Bijoy K, Dippel, Diederik W J, Demchuk, Andrew M, Bracard, Serge, Dávalos, Antoni, Majoie, Charles B L M, Ford, Gary A, de la Ossa, Natalia Pérez, Kelly, Michael, Bourcier, Romain, Roos, Yvo B W E M, Bang, Oh Young, Nogueira, Raul G, Devlin, Thomas G, Clarençon, Frédéric, Burns, Paul, Carpenter, Jeffrey, Yavagal, Dileep R, Pereira, Vitor Mendes, Quesada, Helena, Epstein, Jonathan, Rubiera, Marta, Urra, Xabier, Micard, Emilien, Brown, Scott, Guillemin, Francis, van Oostenbrugge, Robert J, Jovin, Tudor G, and Hill, Michael D
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- 2018
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59. Acute myocardial infarction and ischaemic stroke: differences and similarities in reperfusion therapies—a review.
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Scheldeman, Lauranne, Sinnaeve, Peter, Albers, Gregory W, Lemmens, Robin, and Werf, Frans Van de
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ST elevation myocardial infarction ,CEREBRAL angiography ,PERCUTANEOUS coronary intervention ,ENDOVASCULAR surgery ,ISCHEMIC stroke ,MYOCARDIAL infarction - Abstract
Acute ST-elevation myocardial infarction (STEMI) and acute ischaemic stroke (AIS) share a number of similarities. However, important differences in pathophysiology demand a disease-tailored approach. In both conditions, fast treatment plays a crucial role as ischaemia and eventually infarction develop rapidly. Furthermore, in both fields, the introduction of fibrinolytic treatments historically preceded the implementation of endovascular techniques. However, in contrast to STEMI, only a minority of AIS patients will eventually be considered eligible for reperfusion treatment. Non-invasive cerebral imaging always precedes cerebral angiography and thrombectomy, whereas coronary angiography is not routinely preceded by non-invasive cardiac imaging in patients with STEMI. In the late or unknown time window, the presence of specific patterns on brain imaging may help identify AIS patients who benefit most from reperfusion treatment. For STEMI, a uniform time window for reperfusion up to 12 h after symptom onset, based on old placebo-controlled trials, is still recommended in guidelines and generally applied. Bridging fibrinolysis preceding endovascular treatment still remains the mainstay of reperfusion treatment in AIS, while primary percutaneous coronary intervention is the strategy of choice in STEMI. Shortening ischaemic times by fine-tuning collaboration networks between ambulances, community hospitals, and tertiary care hospitals, optimizing bridging fibrinolysis, and reducing ischaemia–reperfusion injury are important topics for further research. The aim of this review is to provide insights into the common as well as diverging pathophysiology behind current reperfusion strategies and to explore new ways to enhance their clinical benefit. [ABSTRACT FROM AUTHOR]
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- 2024
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60. Clinical change during inter-hospital transfer for thrombectomy: Incidence, associated factors, and relationship with outcome.
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Seners, Pierre, Ter Schiphorst, Adrien, Wouters, Anke, Yuen, Nicole, Mlynash, Michael, Arquizan, Caroline, Heit, Jeremy J, Kemp, Stephanie, Christensen, Soren, Sablot, Denis, Wacongne, Anne, Lalu, Thibault, Costalat, Vincent, Albers, Gregory W, and Lansberg, Maarten G
- Abstract
Background: Patients with acute ischemic stroke with a large vessel occlusion (LVO) admitted to non endovascular-capable centers often require inter-hospital transfer for thrombectomy. We aimed to describe the incidence of substantial clinical change during transfer, the factors associated with clinical change, and its relationship with 3-month outcome. Methods: We analyzed data from two cohorts of acute stroke patients transferred for thrombectomy to a comprehensive center (Stanford, USA, November 2019 to January 2023; Montpellier, France, January 2015 to January 2017), regardless of whether thrombectomy was eventually attempted. Patients were included if they had evidence of an LVO at the referring hospital and had a National Institute of Health Stroke Scale (NIHSS) score documented before and immediately after transfer. Inter-hospital clinical change was categorized as improvement (⩾4 points and ⩾25% decrease between the NIHSS score in the referring hospital and upon comprehensive center arrival), deterioration (⩾4 points and ⩾25% increase), or stability (neither improvement nor deterioration). The stable group was considered as the reference and was compared to the improvement or deterioration groups separately. Results: A total of 504 patients were included, of whom 22% experienced inter-hospital improvement, 14% deterioration, and 64% were stable. Pre-transfer variables independently associated with clinical improvement were intravenous thrombolysis use, more distal occlusions, and lower serum glucose; variables associated with deterioration included more proximal occlusions and higher serum glucose. On post-transfer imaging, clinical improvement was associated with arterial recanalization and smaller infarct growth and deterioration with larger infarct growth. As compared to stable patients, those with clinical improvement had better 3-month functional outcome (adjusted common odds ratio (cOR) = 2.43; 95% confidence interval (CI) = 1.59–3.71; p < 0.001), while those with deterioration had worse outcome (adjusted cOR = 0.60; 95% CI = 0.37–0.98; p = 0.044). Conclusion: Substantial inter-hospital clinical changes are frequently observed in LVO-related ischemic strokes, with significant impact on functional outcome. There is a need to develop treatments that improves the clinical status during transfer. Data access statement: The data that support the findings of this study are available upon reasonable request. [ABSTRACT FROM AUTHOR]
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- 2024
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61. Association between occlusion location, net water uptake and ischemic lesion growth in large vessel anterior circulation strokes.
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Winkelmeier, Laurens, Heit, Jeremy J, Broocks, Gabriel, Prüter, Julia, Heitkamp, Christian, Schell, Maximilian, Albers, Gregory W, Lansberg, Maarten G, Wintermark, Max, Kemmling, André, Stracke, Christian Paul, Guenego, Adrien, Paech, Daniel, Fiehler, Jens, and Faizy, Tobias D
- Abstract
Ischemic lesion net water uptake (NWU) represents a quantitative imaging biomarker for cerebral edema in acute ischemic stroke. Data on NWU for distinct occlusion locations remain scarce, but might help to improve the prognostic value of NWU. In this retrospective multicenter cohort study, we compared NWU between patients with proximal large vessel occlusion (pLVO; ICA or proximal M1) and distal large vessel occlusion (dLVO; distal M1 or M2). NWU was quantified by densitometric measurements of the early ischemic region. Arterial collateral status was assessed using the Maas scale. Regression analysis was used to investigate the relationship between occlusion location, NWU and ischemic lesion growth. A total of 685 patients met inclusion criteria. Early ischemic lesion NWU was higher in patients with pLVO compared with dLVO (7.7% vs 3.9%, P <.001). The relationship between occlusion location and NWU was partially mediated by arterial collateral status. NWU was associated with absolute ischemic lesion growth between admission and follow-up imaging (β estimate, 5.50, 95% CI, 3.81–7.19, P <.001). This study establishes a framework for the relationship between occlusion location, arterial collateral status, early ischemic lesion NWU and ischemic lesion growth. Future prognostic thresholds for NWU might be optimized by adjusting for the occlusion location. [ABSTRACT FROM AUTHOR]
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- 2024
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62. Tilt-Corrected Region Boundaries May Enhance the Alberta Stroke Program Early Computed Tomography Score for Less Experienced Raters
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Culbertson, Collin J., Christensen, Søren, Mlynash, Michael, Heit, Jeremy J., Federau, Christian, Sells, Christina Mijalski, Legault, Catherine, McCaslin, Addason F.H., Werbaneth, Katherine, Albers, Gregory W., and Lansberg, Maarten G.
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- 2020
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63. Stroke and high-risk TIA outcomes with reduction of treatment duration when treatment initiated in emergency rooms (SHORTER-study)
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Alhazzani, Adel, primary, Alajlan, Fahad S, additional, Alkhathaami, Ali M, additional, Al-Senani, Fahmi Mohammed, additional, Muayqil, Taim A, additional, Alghamdi, Saeed A, additional, AlKawi, Ammar, additional, AlZahrani, Saeed, additional, Bakheet, Majid, additional, Aljohani, Mohammed, additional, Taher, Nouran, additional, Almutairi, Abdulkarim, additional, AlQarni, Mustafa, additional, Alsalman, Sadiq, additional, Alqahtani, Saeed A, additional, Almansour, Nouf, additional, Abukhamsin, Laila, additional, Mouminah, Amr, additional, Almodarra, Nehal, additional, Mohamed, Gamal, additional, Almodhy, Meshal, additional, Albogumi, Eid, additional, Alzawahmah, Mohamad, additional, Alreshaid, Abdulrahman, additional, Akhtar, Naveed, additional, Hussain, Muhammad Shazam, additional, Albers, Gregory W, additional, and Shuaib, Ashfaq, additional
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- 2024
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64. Stroke in the Time of Circadian Medicine
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Mergenthaler, Philipp, primary, Balami, Joyce S., additional, Neuhaus, Ain A., additional, Mottahedin, Amin, additional, Albers, Gregory W., additional, Rothwell, Peter M., additional, Saver, Jeffrey L., additional, Young, Martin E., additional, and Buchan, Alastair M., additional
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- 2024
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65. Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke
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Yedavalli, Vivek S, primary, Koneru, Manisha, additional, Hoseinyazdi, Meisam, additional, Greene, Cynthia, additional, Lakhani, Dhairya A, additional, Xu, Risheng, additional, Luna, Licia P, additional, Caplan, Justin M, additional, Dmytriw, Adam A, additional, Guenego, Adrien, additional, Heit, Jeremy J, additional, Albers, Gregory W, additional, Wintermark, Max, additional, Gonzalez, L Fernando, additional, Urrutia, Victor C, additional, Huang, Judy, additional, Nael, Kambiz, additional, Leigh, Richard, additional, Marsh, Elisabeth B, additional, Hillis, Argye E, additional, and Llinas, Rafael H, additional
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- 2024
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66. Clinical relevance of intracranial hemorrhage after thrombectomy versus medical management for large core infarct: a secondary analysis of the SELECT2 randomized trial
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Chen, Michael, primary, Joshi, Krishna C, additional, Kolb, Bradley, additional, Sitton, Clark W, additional, Pujara, Deep Kiritbhai, additional, Abraham, Michael G, additional, Ortega-Gutierrez, Santiago, additional, Kasner, Scott E, additional, Hussain, Shazam M, additional, Churilov, Leonid, additional, Blackburn, Spiros, additional, Sundararajan, Sophia, additional, Hu, Yin C, additional, Herial, Nabeel, additional, Arenillas, Juan F, additional, Tsai, Jenny P, additional, Budzik, Ronald F, additional, Hicks, William, additional, Kozak, Osman, additional, Yan, Bernard, additional, Cordato, Dennis, additional, Manning, Nathan W, additional, Parsons, Mark, additional, Hanel, Ricardo A, additional, Aghaebrahim, Amin, additional, Wu, Teddy, additional, Cardona Portela, Pere, additional, Gandhi, Chirag D, additional, Al-Mufti, Fawaz, additional, Perez de la Ossa, Natalia, additional, Schaafsma, Joanna, additional, Blasco, Jordi, additional, Sangha, Navdeep, additional, Warach, Steven, additional, Kleinig, Timothy J, additional, Johns, Hannah, additional, Shaker, Faris, additional, Abdulrazzak, Mohammad A, additional, Ray, Abhishek, additional, Sunshine, Jeffery, additional, Opaskar, Amanda, additional, Duncan, Kelsey R, additional, Xiong, Wei, additional, Al-Shaibi, Faisal K, additional, Samaniego, Edgar A, additional, Nguyen, Thanh N, additional, Fifi, Johanna T, additional, Tjoumakaris, Stavropoula I, additional, Jabbour, Pascal, additional, Mendes Pereira, Vitor, additional, Lansberg, Maarten G, additional, Sila, Cathy, additional, Bambakidis, Nicholas C, additional, Davis, Stephen, additional, Wechsler, Lawrence, additional, Albers, Gregory W, additional, Grotta, James C, additional, Ribo, Marc, additional, Hassan, Ameer E, additional, Campbell, Bruce, additional, Hill, Michael D, additional, and Sarraj, Amrou, additional
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- 2024
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67. Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection
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Albers, Gregory W., primary, Jumaa, Mouhammad, additional, Purdon, Barbara, additional, Zaidi, Syed F., additional, Streib, Christopher, additional, Shuaib, Ashfaq, additional, Sangha, Navdeep, additional, Kim, Minjee, additional, Froehler, Michael T., additional, Schwartz, Neil E., additional, Clark, Wayne M., additional, Kircher, Charles E., additional, Yang, Ming, additional, Massaro, Lori, additional, Lu, Xiao-Yu, additional, Rippon, Gregory A., additional, Broderick, Joseph P., additional, Butcher, Ken, additional, Lansberg, Maarten G., additional, Liebeskind, David S., additional, Nouh, Amre, additional, Schwamm, Lee H., additional, and Campbell, Bruce C.V., additional
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- 2024
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68. Abstract WP118: Ischemic Core Volumes and Collateral Status Have Diurnal Fluctuations - A Retrospective Cohort Study of 18137 Patients Using Automated Perfusion Imaging
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Lun, Ronda, primary, Sreekrishnan, Anirudh, additional, and Albers, Gregory W, additional
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- 2024
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69. Abstract TP204: Performance of Rapidai NCCT Stroke Software in Colombia's Early Stroke System: Preliminary Results
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Granja, Manuel F, primary, Ramirez, Karen, additional, Espinel, Laura, additional, Salazar, Antonio J, additional, Mejia, Juan A, additional, Torres, Oscar, additional, Morillo, Anibal, additional, Bermudez, Sonia, additional, Useche, Nicolas, additional, and Albers, Gregory W, additional
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- 2024
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70. Abstract TP171: Nationwide Diurnal Pattern Among Intracerebral Hemorrhage Incidence and Volume
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Sreekrishnan, Anirudh, primary, Lun, Ronda, additional, and Albers, Gregory W, additional
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- 2024
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71. Abstract WP117: Improvement of Collateral Status in Thrombectomy-Eligible Stroke Patients During Inter-Hospital Transfer: Association With Clinical Factors and Outcome
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Wouters, Anke, primary, Seners, Pierre, additional, Yuen, Nicole, additional, Mlynash, Michael, additional, Heit, Jeremy J, additional, Kemp, Stephanie M, additional, Christensen, Soren, additional, Albers, Gregory W, additional, Lemmens, Robin, additional, and Lansberg, Maarten G, additional
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- 2024
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72. Abstract 129: An Automated Perfusion Collateral Score as a Tool to Predict Inter-Hospital Infarct Growth and Functional Outcome
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Wouters, Anke, primary, Seners, Pierre, additional, Yuen, Nicole, additional, Mlynash, Michael, additional, Heit, Jeremy J, additional, Kemp, Stephanie M, additional, Christensen, Soren, additional, Albers, Gregory W, additional, Lemmens, Robin, additional, and Lansberg, Maarten G, additional
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- 2024
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73. Abstract TMP37: Improved Outcomes for Acute Ischemic Stroke Patients After Implementation of the RapidAI Platform in a Comprehensive Stroke Center in Santiago, Chile
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Lavados, Pablo, primary, Gonzalez, Pablo, additional, Olavarría, Verónica, additional, and Albers, Gregory W, additional
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- 2024
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74. Abstract 156: Cerebral Edema in Patients Presenting With Large Ischemic Core Undergoing Thrombectomy versus Medical Therapy: Secondary Analysis of SELECT 2 Trial
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Ng, Felix, primary, Johns, Hannah Tabitha, additional, churilov, leonid, additional, Yogendrakumar, Vignan, additional, Hassan, Ameer E, additional, Abraham, Michael G, additional, Ortega-Gutierrez, Santiago, additional, Hussain, M. Shazam, additional, Chen, Michael, additional, Wechsler, Lawrence, additional, Nguyen, Thanh, additional, Johanna, Fifi, additional, Ribo, Marc, additional, sitton, clark, additional, Mendes Pereira, Vitor, additional, Kasner, Scott, additional, Lansberg, Maarten G, additional, Pujara, Deep K, additional, Sharma, Gaganjyoti, additional, Guha, Prodipta, additional, Hill, Michael D, additional, Parsons, Mark W, additional, Davis, Stephen M, additional, Grotta, James C, additional, Albers, Gregory W, additional, Campbell, Bruce, additional, and Sarraj, Amrou, additional
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- 2024
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75. Abstract WMP66: Detecting Medium Vessel Occlusions and Collateral Assessment With Multimodality AI Approach
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Sowlat, Mohammad Mahdi, primary, Zamarud, Aroosa, additional, Albers, Gregory W, additional, Campbell, Bruce, additional, Heit, Jeremy J, additional, and Spiotta, Alejandro M, additional
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- 2024
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76. Abstract WP197: Poor Venous Outflow is Associated With Ischemic Core Growth During Transfer in Acute Ischemic Stroke Patients With a Large Vessel Occlusion
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Zamarud, Aroosa, primary, Seners, Pierre, additional, Mlynash, Michael, additional, Wouters, Anke, additional, Lugo, Leonel, additional, Faizy, Tobias, additional, Lansberg, Maarten G, additional, Albers, Gregory W, additional, and Heit, Jeremy J, additional
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- 2024
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77. Abstract WP313: Towards Molecular Profiling of Transient Ischemic Attack Mimics for Triage
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Carmona, Paulina, primary, Lenz, Garreck, additional, Jickling, Glen, additional, Knepp, Bodie, additional, Amini, Hajar, additional, Hull, Heather, additional, Albers, Gregory W, additional, George, Paul, additional, Cucchiara, Brett L, additional, PENN, ANDREW, additional, RANGARAJU, Srikant, additional, Nahab, Fadi B, additional, Bruce, Beau, additional, Sharp, Frank R, additional, Stamova, Boryana, additional, and Ander, Bradley, additional
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- 2024
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78. Nationwide diurnal pattern among intracerebral hemorrhage incidence and volume
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Sreekrishnan, Anirudh, primary, Lun, Ronda, additional, and Albers, Gregory W, additional
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- 2024
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79. Abstract TMP36: Anatomical Predictors of Gastrostomy Tube Placement After Large Vessel Occlusion Ischemic Stroke
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Ikramuddin, Salman, primary, McCullough-Hicks, Margy E, additional, Christensen, Soren, additional, Ruiz-Betancourt, Daniel, additional, Mlynash, Michael, additional, and Albers, Gregory W, additional
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- 2024
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80. Abstract 23: Results of CRISP2: CTP and CTA Assessment of Collaterals Predicts Inter-Hospital Infarct Growth
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Wouters, Anke, primary, Seners, Pierre, additional, Yuen, Nicole, additional, Mlynash, Michael, additional, Heit, Jeremy J, additional, Kemp, Stephanie M, additional, Christensen, Soren, additional, Albers, Gregory W, additional, Lemmens, Robin, additional, and Lansberg, Maarten G, additional
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- 2024
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81. Perfusion Profiles May Differ Between Asymptomatic Versus Symptomatic Internal Carotid Artery Occlusion
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Chang, Ting-Yu, primary, Christensen, Soren, additional, Mlynash, Michael, additional, Heit, Jeremy J., additional, Marks, Michael P., additional, Lee, Sarah, additional, McCullough-Hicks, Margy E., additional, Ostojic, Lili Velickovic, additional, Kemp, Stephanie, additional, Albers, Gregory W., additional, Srivatsan, Aditya, additional, Lee, Tsong-Hai, additional, and Lansberg, Maarten G., additional
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- 2024
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82. Effect of endovascular reperfusion in relation to site of arterial occlusion
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Lemmens, Robin, Hamilton, Scott A, Liebeskind, David S, Tomsick, Tom A, Demchuk, Andrew M, Nogueira, Raul G, Marks, Michael P, Jahan, Reza, Gralla, Jan, Yoo, Albert J, Yeatts, Sharon D, Palesch, Yuko Y, Saver, Jeffrey L, Pereira, Vitor M, Broderick, Joseph P, Albers, Gregory W, and Lansberg, Maarten G
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Trials and Supportive Activities ,Neurosciences ,Stroke ,Clinical Research ,Brain Disorders ,Cardiovascular ,Arterial Occlusive Diseases ,Carotid Artery ,Internal ,Endovascular Procedures ,Female ,Humans ,Infarction ,Middle Cerebral Artery ,Male ,Prospective Studies ,Randomized Controlled Trials as Topic ,Reperfusion ,Thrombectomy ,Treatment Outcome ,DEFUSE 2 ,IMS III ,STAR ,and SWIFT trialists ,DEFUSE 2 IMS III STAR and SWIFT trialists ,Cognitive Sciences ,Neurology & Neurosurgery ,Clinical sciences - Abstract
ObjectiveTo assess whether the association between reperfusion and improved clinical outcomes after stroke differs depending on the site of the arterial occlusive lesion (AOL).MethodsWe pooled data from Solitaire With the Intention for Thrombectomy (SWIFT), Solitaire FR Thrombectomy for Acute Revascularisation (STAR), Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution Study 2 (DEFUSE 2), and Interventional Management of Stroke Trial (IMS III) to compare the strength of the associations between reperfusion and clinical outcomes in patients with internal carotid artery (ICA), proximal middle cerebral artery (MCA) (M1), and distal MCA (M2/3/4) occlusions.ResultsAmong 710 included patients, the site of the AOL was the ICA in 161, the proximal MCA in 389, and the distal MCA in 160 patients (M2 = 131, M3 = 23, and M4 = 6). Reperfusion was associated with an increase in the rate of good functional outcome (modified Rankin Scale [mRS] score 0-2) in patients with ICA (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.7-7.2) and proximal MCA occlusions (OR 6.2, 95% CI 3.8-10.2), but not in patients with distal MCA occlusions (OR 1.4, 95% CI 0.8-2.6). Among patients with M2 occlusions, a subset of the distal MCA cohort, reperfusion was associated with excellent functional outcome (mRS 0-1; OR 2.2, 95% CI 1.0-4.7).ConclusionsThe association between endovascular reperfusion and better clinical outcomes is more profound in patients with ICA and proximal MCA occlusions compared to patients with distal MCA occlusions. Because there are limited data from randomized controlled trials on the effect of endovascular therapy in patients with distal MCA occlusions, these results underscore the need for inclusion of this subgroup in future endovascular therapy trials.
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- 2016
83. Imaging in StrokeNet: Realizing the Potential of Big Data.
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Liebeskind, David S, Albers, Gregory W, Crawford, Karen, Derdeyn, Colin P, George, Mark S, Palesch, Yuko Y, Toga, Arthur W, Warach, Steven, Zhao, Wenle, Brott, Thomas G, Sacco, Ralph L, Khatri, Pooja, Saver, Jeffrey L, Cramer, Steven C, Wolf, Steven L, Broderick, Joseph P, and Wintermark, Max
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Humans ,Brain Ischemia ,Diagnostic Imaging ,Statistics as Topic ,Stroke ,Neuroimaging ,collateral circulation ,diagnostic imaging ,stroke ,Neurology & Neurosurgery ,Clinical Sciences ,Cardiorespiratory Medicine and Haematology ,Neurosciences - Published
- 2015
84. J. L. Saver et al.
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Saver, Jeffrey L, Goyal, Mayank, Bonafe, Alain, Diener, Hans‐Christoph, Levy, Elad I, Pereira, Vitor M, Albers, Gregory W, Cognard, Christophe, Cohen, David J, Hacke, Werner, Jansen, Olav, Jovin, Tudor G, Mattle, Heinrich P, Nogueira, Raul G, Siddiqui, Adnan H, Yavagal, Dileep R, Devlin, Thomas G, Lopes, Demetrius K, Reddy, Vivek, de Rochemont, Richard du Mesnil, Jahan, Reza, and Investigators, SWIFT PRIME
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Biomedical and Clinical Sciences ,Clinical Sciences ,Stroke ,Bioengineering ,Neurosciences ,Clinical Trials and Supportive Activities ,Clinical Research ,Brain Disorders ,Adolescent ,Adult ,Aged ,Aged ,80 and over ,Brain Ischemia ,Female ,Fibrinolytic Agents ,Follow-Up Studies ,Humans ,Injections ,Intravenous ,Magnetic Resonance Angiography ,Male ,Middle Aged ,Prospective Studies ,Severity of Illness Index ,Stents ,Thrombectomy ,Tissue Plasminogen Activator ,Tomography Scanners ,X-Ray Computed ,Treatment Outcome ,Young Adult ,acute ischemic stroke ,clinical trial ,endovascular ,recanalization ,stent retriever ,thrombolysis ,SWIFT PRIME Investigators ,Neurology & Neurosurgery ,Clinical sciences ,Allied health and rehabilitation science - Abstract
RationaleEarly reperfusion in patients experiencing acute ischemic stroke is critical, especially for patients with large vessel occlusion who have poor prognosis without revascularization. Solitaire™ stent retriever devices have been shown to immediately restore vascular perfusion safely, rapidly, and effectively in acute ischemic stroke patients with large vessel occlusions.AimThe aim of the study was to demonstrate that, among patients with large vessel, anterior circulation occlusion who have received intravenous tissue plasminogen activator, treatment with Solitaire revascularization devices reduces degree of disability 3 months post stroke.DesignThe study is a global multicenter, two-arm, prospective, randomized, open, blinded end-point trial comparing functional outcomes in acute ischemic stroke patients who are treated with either intravenous tissue plasminogen activator alone or intravenous tissue plasminogen activator in combination with the Solitaire device. Up to 833 patients will be enrolled.ProceduresPatients who have received intravenous tissue plasminogen activator are randomized to either continue with intravenous tissue plasminogen activator alone or additionally proceed to neurothrombectomy using the Solitaire device within six-hours of symptom onset.Study outcomesThe primary end-point is 90-day global disability, assessed with the modified Rankin Scale (mRS). Secondary outcomes include mortality at 90 days, functional independence (mRS ≤ 2) at 90 days, change in National Institutes of Health Stroke Scale at 27 h, reperfusion at 27 h, and thrombolysis in cerebral infarction 2b/3 flow at the end of the procedure.AnalysisStatistical analysis will be conducted using simultaneous success criteria on the overall distribution of modified Rankin Scale (Rankin shift) and proportions of subjects achieving functional independence (mRS 0-2).
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- 2015
85. Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke.
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Saver, Jeffrey L, Goyal, Mayank, Bonafe, Alain, Diener, Hans-Christoph, Levy, Elad I, Pereira, Vitor M, Albers, Gregory W, Cognard, Christophe, Cohen, David J, Hacke, Werner, Jansen, Olav, Jovin, Tudor G, Mattle, Heinrich P, Nogueira, Raul G, Siddiqui, Adnan H, Yavagal, Dileep R, Devlin, Thomas G, Lopes, Demetrius K, Reddy, Vivek, du Mesnil de Rochemont, Richard, Jahan, Reza, and SWIFT PRIME Investigators
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SWIFT PRIME Investigators ,Humans ,Brain Ischemia ,Tissue Plasminogen Activator ,Fibrinolytic Agents ,Magnetic Resonance Angiography ,Treatment Outcome ,Thrombectomy ,Injections ,Intravenous ,Severity of Illness Index ,Follow-Up Studies ,Prospective Studies ,Stents ,Tomography Scanners ,X-Ray Computed ,Adolescent ,Adult ,Aged ,Aged ,80 and over ,Middle Aged ,Female ,Male ,Stroke ,Young Adult ,acute ischemic stroke ,clinical trial ,endovascular ,recanalization ,stent retriever ,thrombolysis ,Injections ,Intravenous ,Tomography Scanners ,X-Ray Computed ,and over ,Clinical Sciences ,Neurosciences ,Neurology & Neurosurgery - Abstract
RationaleEarly reperfusion in patients experiencing acute ischemic stroke is critical, especially for patients with large vessel occlusion who have poor prognosis without revascularization. Solitaire™ stent retriever devices have been shown to immediately restore vascular perfusion safely, rapidly, and effectively in acute ischemic stroke patients with large vessel occlusions.AimThe aim of the study was to demonstrate that, among patients with large vessel, anterior circulation occlusion who have received intravenous tissue plasminogen activator, treatment with Solitaire revascularization devices reduces degree of disability 3 months post stroke.DesignThe study is a global multicenter, two-arm, prospective, randomized, open, blinded end-point trial comparing functional outcomes in acute ischemic stroke patients who are treated with either intravenous tissue plasminogen activator alone or intravenous tissue plasminogen activator in combination with the Solitaire device. Up to 833 patients will be enrolled.ProceduresPatients who have received intravenous tissue plasminogen activator are randomized to either continue with intravenous tissue plasminogen activator alone or additionally proceed to neurothrombectomy using the Solitaire device within six-hours of symptom onset.Study outcomesThe primary end-point is 90-day global disability, assessed with the modified Rankin Scale (mRS). Secondary outcomes include mortality at 90 days, functional independence (mRS ≤ 2) at 90 days, change in National Institutes of Health Stroke Scale at 27 h, reperfusion at 27 h, and thrombolysis in cerebral infarction 2b/3 flow at the end of the procedure.AnalysisStatistical analysis will be conducted using simultaneous success criteria on the overall distribution of modified Rankin Scale (Rankin shift) and proportions of subjects achieving functional independence (mRS 0-2).
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- 2015
86. Prediction of Stroke Infarct Growth Rates by Baseline Perfusion Imaging
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Wouters, Anke, Robben, David, Christensen, Soren, Marquering, Henk A., Roos, Yvo B.W.E.M., van Oostenbrugge, Robert J., van Zwam, Wim H., Dippel, Diederik W.J., Majoie, Charles B.L.M., Schonewille, Wouter J., van der Lugt, Aad, Lansberg, Maarten, Albers, Gregory W., Suetens, Paul, and Lemmens, Robin
- Published
- 2021
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87. Contributors
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Abrams, Gary M., primary, Albers, Gregory W., additional, Amans, Matthew R., additional, Aminoff, Michael J., additional, Batla, Amit, additional, Betjemann, John P., additional, Camilleri, Michael, additional, Chen, Robert, additional, Christine, Chadwick W., additional, Coleman, Kyle J., additional, Davies-Jones, G.A.B., additional, DeAngelis, Lisa M., additional, Dhand, Amar, additional, Dillon, William P., additional, Douglas, Vanja C., additional, Fox, Christine, additional, Furman, Joseph M., additional, Gelb, Douglas J., additional, Gladstone, David J., additional, Glynn, Simon M., additional, Goodin, Douglas S., additional, Goodman, Brent P., additional, Greenlee, John E., additional, Guterman, Elan, additional, Halabi, Cathra, additional, Hallett, Mark, additional, Halperin, John J., additional, Harris, Shelby, additional, Hemphill, J. Claude, additional, Hurko, Orest, additional, Irani, Sarosh R., additional, Jo, Jasmin, additional, Josephson, S. Andrew, additional, Kaley, Thomas J., additional, Kim, Anthony S., additional, Ko, Nerissa U., additional, Koshy, Anita A., additional, Kraler, Lironn, additional, Krumholz, Allan, additional, Leonard, John M., additional, Levin, Morris, additional, Manno, Edward M., additional, Mastaglia, Frank L., additional, Maurer, Carine W., additional, McCall, Andrew A., additional, Messing, Robert O., additional, Miravalle, Augusto, additional, Monderer, Renee, additional, Morren, John A., additional, Muccilli, Alexandra D., additional, Muir, Ryan T., additional, Murphy, Olwen C., additional, Nash, Kendall, additional, Ooi, Winnie W., additional, Pal, Pramod K., additional, Panicker, Jalesh N., additional, Parent, Jack M., additional, Peluso, Michael J., additional, Perfect, John R., additional, Peyvandi, Shabnam, additional, Pfeiffer, Ronald F., additional, Phillips, Steven M., additional, Poncelet, Ann Noelle, additional, Prasad, Sashank, additional, Prasad, Shweta, additional, Probasco, John C., additional, Purdy, Kaylynn, additional, Rabinstein, Alejandro A., additional, Ralph, Jeffrey W., additional, Ramachandran, Prashanth S., additional, Roos, Karen L., additional, Rose-Innes, Andrew P., additional, Safarpour, Delaram, additional, Schiff, David, additional, Schipper, Hyman M., additional, Shah, Maulik P., additional, Sharzehi, Kaveh, additional, Shaw, Pamela J., additional, Spudich, Serena, additional, Srinivasan, Jayashri, additional, Stern, Barney J., additional, Sun, Chung-Huan Johnny, additional, Sussman, Jon D., additional, Thorpy, Michael, additional, Verber, Nick S., additional, VoduŠek, David B., additional, Weissenborn, Karin, additional, Williams, Linda S., additional, Wilson, Michael R., additional, and Zochodne, Douglas W., additional
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- 2021
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88. Stroke as a Complication of General Medical Disorders
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Kraler, Lironn, primary and Albers, Gregory W., additional
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- 2021
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89. Predictors of Functional Dependence Despite Successful Revascularization in Large-Vessel Occlusion Strokes
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Shi, Zhong-Song, Liebeskind, David S, Xiang, Bin, Ge, Sijian Grace, Feng, Lei, Albers, Gregory W, Budzik, Ronald, Devlin, Thomas, Gupta, Rishi, Jansen, Olav, Jovin, Tudor G, Killer-Oberpfalzer, Monika, Lutsep, Helmi L, Macho, Juan, Nogueira, Raul G, Rymer, Marilyn, Smith, Wade S, Wahlgren, Nils, and Duckwiler, Gary R
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Biomedical and Clinical Sciences ,Clinical Sciences ,Neurosciences ,Clinical Trials and Supportive Activities ,Stroke ,Clinical Research ,Brain Disorders ,Aged ,Aged ,80 and over ,Brain Infarction ,Brain Ischemia ,Cerebral Revascularization ,Clinical Trials as Topic ,Female ,Humans ,Male ,Middle Aged ,Multicenter Studies as Topic ,Predictive Value of Tests ,Recovery of Function ,Severity of Illness Index ,Thrombectomy ,Thrombolytic Therapy ,stroke ,Multi MERCI ,TREVO ,and TREVO 2 Investigators ,Cardiorespiratory Medicine and Haematology ,Neurology & Neurosurgery ,Clinical sciences ,Allied health and rehabilitation science - Abstract
Background and purposeHigh revascularization rates in large-vessel occlusion strokes treated by mechanical thrombectomy are not always associated with good clinical outcomes. We evaluated predictors of functional dependence despite successful revascularization among patients with acute ischemic stroke treated with thrombectomy.MethodsWe analyzed the pooled data from the Multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI), Thrombectomy Revascularization of Large Vessel Occlusions in Acute Ischemic Stroke (TREVO), and TREVO 2 trials. Successful revascularization was defined as thrombolysis in cerebral infarction score 2b or 3. Functional dependence was defined as a score of 3 to 6 on the modified Rankin Scale at 3 months. We assessed relationship of demographic, clinical, angiographic characteristics, and hemorrhage with functional dependence despite successful revascularization.ResultsTwo hundred and twenty-eight patients with successful revascularization had clinical outcome follow-up. The rates of functional dependence with endovascular success were 48.6% for Trevo thrombectomy and 58.0% for Merci thrombectomy. Age (odds ratio, 1.04; 95% confidence interval, 1.02-1.06 per 1-year increase), National Institutes of Health Stroke Scale score (odds ratio, 1.08; 95% confidence interval, 1.02-1.15 per 1-point increase), and symptom onset to endovascular treatment time (odds ratio, 1.11; 95% confidence interval, 1.01-1.22 per 30-minute delay) were predictors of functional dependence despite successful revascularization. Symptom onset to reperfusion time beyond 5 hours was associated with functional dependence. All subjects with symptomatic intracranial hemorrhage had functional dependence.ConclusionsOne half of patients with successful mechanical thrombectomy do not have good outcomes. Age, severe neurological deficits, and delayed endovascular treatment were associated with functional dependence despite successful revascularization. Our data support efforts to minimize delays to endovascular therapy in patients with acute ischemic stroke to improve outcomes.Clinical trial registration urlhttp://www.clinicaltrials.gov. Unique identifier: NCT00318071, NCT01088672, and NCT01270867.
- Published
- 2014
90. Matched-pair analysis of patients with ischemic stroke undergoing thrombectomy using next-generation balloon guide catheters.
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Kim, Lily H., Choi, John, Zhou, James, Wolman, Dylan, Pendharkar, Arjun V., Lansberg, Maarten G., Albers, Gregory W., Dodd, Robert, Do, Huy M., Pulli, Benjamin, Heit, Jeremy J., and Telischak, Nicholas A.
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T-test (Statistics) ,STATISTICAL significance ,PAIRED comparisons (Mathematics) ,SEX distribution ,MULTIPLE regression analysis ,TREATMENT effectiveness ,RETROSPECTIVE studies ,AGE distribution ,CHI-squared test ,MANN Whitney U Test ,MULTIVARIATE analysis ,DESCRIPTIVE statistics ,SURGICAL complications ,ODDS ratio ,ISCHEMIC stroke ,CATHETERS ,MEDICAL records ,ACQUISITION of data ,STATISTICS ,THROMBECTOMY ,CONFIDENCE intervals ,DATA analysis software - Abstract
Background Balloon guide catheters (BGCs) have not been widely adopted, possibly due to the incompatibility of past-generation BGCs with large-bore intermediate catheters. The next-generation BGC is compatible with large-bore catheters. We compared outcomes of thrombectomy cases using BGCs versus conventional guide catheters. Methods We conducted a retrospective study of 110 thrombectomy cases using BGCs (n=55) and non-BGCs (n=55). Sixty consecutive thrombectomy cases in whom the BOBBY BGC was used at a single institution between February 2021 and March 2022 were identified. Of these, 55 BGC cases were 1:1 matched with non-BGC cases by proceduralists, age, gender, stent retriever + aspiration device versus aspiration-only, and site of occlusion. First-pass effect was defined as Thrombolysis In Cerebral Infarction 2b or higher with a single pass. Results The BGC and non-BGC cohorts had similar mean age (67.2 vs 68.9 years), gender distribution (43.6% vs 47.3% women), median initial National Institutes of Health Stroke Scale score (14 vs 15), and median pretreatment ischemic core volumes (12 mL vs 11.5 mL). BGC and non-BGC cases had similar rates of single pass (60.0% vs 54.6%), first-pass effect (58.2% vs 49.1%), and complications (1.8% vs 9.1%). In aspiration-only cases, the BGC cohort had a significantly higher rate of first-pass effect (100% vs 50.0%, p=0.01). BGC was associated with a higher likelihood of achieving a modified Rankin Scale score of 2 at discharge (OR 7.76, p=0.02). No additional procedural time was required for BGC cases (46.7 vs 48.2 min). Conclusion BGCs may be safely adopted with comparable procedural efficacy, benefits to aspirationonly techniques, and earlier functional improvement compared with conventional guide catheters. [ABSTRACT FROM AUTHOR]
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- 2024
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91. A Clinical and Imaging Fused Deep Learning Model Matches Expert Clinician Prediction of 90-Day Stroke Outcomes.
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Yongkai Liu, Shah, Preya, Yannan Yu, Horsey, Jai, Jiahong Ouyang, Bin Jiang, Guang Yang, Heit, Jeremy J., McCullough-Hicks, Margy E., Hugdal, Stephen M., Wintermark, Max, Michel, Patrik, Liebeskind, David S., Lansberg, Maarten G., Albers, Gregory W., and Zaharchuk, Greg
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- 2024
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92. ASCOD Phenotyping of Stroke With Anterior Large Vessel Occlusion Treated by Mechanical Thrombectomy
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Fontaine, Louis, Sibon, Igor, Raposo, Nicolas, Albucher, Jean-François, Mazighi, Michael, Rousseau, Vanessa, Darcourt, Jean, Thalamas, Claire, Drif, Amel, Sommet, Agnes, Viguier, Alain, Guenego, Adrien, Januel, Anne-Christine, Calvière, Lionel, Menegon, Patrice, Bonneville, Fabrice, Tourdias, Thomas, Albers, Gregory W., Cognard, Christophe, and Olivot, Jean-Marc
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- 2021
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93. Redefining CT perfusion‐based ischemic core estimates for the ghost core in early time window stroke
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Koneru, Manisha, primary, Hoseinyazdi, Meisam, additional, Lakhani, Dhairya A., additional, Greene, Cynthia, additional, Copeland, Karen, additional, Wang, Richard, additional, Xu, Risheng, additional, Luna, Licia, additional, Caplan, Justin M., additional, Dmytriw, Adam A., additional, Guenego, Adrien, additional, Heit, Jeremy J., additional, Albers, Gregory W., additional, Wintermark, Max, additional, Gonzalez, Luis F., additional, Urrutia, Victor C., additional, Huang, Judy, additional, Nael, Kambiz, additional, Leigh, Richard, additional, Marsh, Elisabeth B., additional, Hillis, Argye E., additional, Llinas, Rafael H., additional, and Yedavalli, Vivek S., additional
- Published
- 2023
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94. Early neurological deterioration in patients with acute ischemic stroke is linked to unfavorable cerebral venous outflow
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Heitkamp, Christian, primary, Winkelmeier, Laurens, additional, Heit, Jeremy J, additional, Albers, Gregory W, additional, Lansberg, Maarten G, additional, Kniep, Helge, additional, Broocks, Gabriel, additional, Stracke, Christian Paul, additional, Schell, Maximilian, additional, Guenego, Adrien, additional, Paech, Daniel, additional, Wintermark, Max, additional, Fiehler, Jens, additional, and Faizy, Tobias D, additional
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- 2023
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95. Pretreatment CT perfusion collateral parameters correlate with penumbra salvage in middle cerebral artery occlusion
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Lakhani, Dhairya A., primary, Balar, Aneri B., additional, Koneru, Manisha, additional, Hoseinyazdi, Meisam, additional, Hyson, Nathan, additional, Cho, Andrew, additional, Greene, Cynthia, additional, Xu, Risheng, additional, Luna, Licia, additional, Caplan, Justin, additional, Dmytriw, Adam, additional, Guenego, Adrien, additional, Wintermark, Max, additional, Gonzalez, Fernando, additional, Urrutia, Victor, additional, Huang, Judy, additional, Nael, Kambiz, additional, Rai, Ansaar T., additional, Albers, Gregory W., additional, Heit, Jeremy J., additional, and Yedavalli, Vivek, additional
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- 2023
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96. Larger ischemic cores and poor collaterals among large vessel occlusions presenting in the late evening
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Sreekrishnan, Anirudh, primary, Tiedt, Steffen, additional, Seners, Pierre, additional, Yuen, Nicole, additional, Olivot, Jean-Marc, additional, Mlynash, Michael, additional, Lansberg, Maarten G., additional, Heit, Jeremy J., additional, Lee, Sarah, additional, Michel, Patrik, additional, Strambo, Davide, additional, Salerno, Alexander, additional, Paredes, José Bernardo Escribano, additional, Carrera, Emmanuel, additional, and Albers, Gregory W., additional
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- 2023
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97. Extracellular Vesicle Surface Markers as a Diagnostic Tool in Transient Ischemic Attacks
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Burrello, Jacopo, Bianco, Giovanni, Burrello, Alessio, Manno, Concetta, Maulucci, Francesco, Pileggi, Marco, Nannoni, Stefania, Michel, Patrik, Bolis, Sara, Melli, Giorgia, Vassalli, Giuseppe, Albers, Gregory W., Cianfoni, Alessandro, Barile, Lucio, and Cereda, Carlo W.
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- 2021
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98. The Compensation Index Is Better Associated with DSA ASITN Collateral Score Compared to the Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio
- Author
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Lakhani, Dhairya A., primary, Balar, Aneri B., additional, Koneru, Manisha, additional, Wen, Sijin, additional, Hoseinyazdi, Meisam, additional, Greene, Cynthia, additional, Xu, Risheng, additional, Luna, Licia, additional, Caplan, Justin, additional, Dmytriw, Adam A., additional, Guenego, Adrien, additional, Wintermark, Max, additional, Gonzalez, Fernando, additional, Urrutia, Victor, additional, Huang, Judy, additional, Nael, Kambiz, additional, Rai, Ansaar T., additional, Albers, Gregory W., additional, Heit, Jeremy J., additional, and Yedavalli, Vivek S., additional
- Published
- 2023
- Full Text
- View/download PDF
99. Matched-pair analysis of patients with ischemic stroke undergoing thrombectomy using next-generation balloon guide catheters
- Author
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Kim, Lily H, primary, Choi, John, additional, Zhou, James, additional, Wolman, Dylan, additional, Pendharkar, Arjun V, additional, Lansberg, Maarten G, additional, Albers, Gregory W, additional, Dodd, Robert, additional, Do, Huy M, additional, Pulli, Benjamin, additional, Heit, Jeremy J, additional, and Telischak, Nicholas A, additional
- Published
- 2023
- Full Text
- View/download PDF
100. Current Imaging Strategies for Patient Selection in Acute Ischemic Stroke Trials
- Author
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Tsai, Jenny P., Albers, Gregory W., Zhang, John, Series editor, Lapchak, Paul A., editor, and Zhang, John H., editor
- Published
- 2017
- Full Text
- View/download PDF
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