200 results on '"Adenoma, Sweat Gland surgery"'
Search Results
52. Nodular hidradenocarcinoma over the parotid gland: a pathologic presentation.
- Author
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Verret DJ, Kabbani W, and DeFatta RJ
- Subjects
- Adenoma, Sweat Gland surgery, Adult, Humans, Male, Parotid Gland surgery, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Parotid Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
Background: Nodular hidradenocarcinoma (NHAC), an eccrine carcinoma, has been reported in the dermatology and pathology literature, but few references have been made in the otolaryngology literature even though the head and neck is a common site of occurrence., Methods: A case report of a 37-year-old Hispanic man with a right-sided neck mass diagnosed preoperatively as a parotid mass by imaging and fine-needle aspiration is presented. After presentation at our multidisciplinary tumor board, excision of the mass was undertaken., Results: Final pathology revealed a NHAC, which is presented in our report., Conclusion: NHAC is an aggressive malignant tumor that is often misdiagnosed preoperatively and that must be treated with aggressive multimodality therapy for increased survival.
- Published
- 2007
- Full Text
- View/download PDF
53. [Giant tumor of the orbit--a case of hidradenoma].
- Author
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Burduk PK, Seredyka-Burduk M, and Olejarz E
- Subjects
- Adenoma, Sweat Gland surgery, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Orbital Neoplasms surgery, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Orbital Neoplasms diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
Orbital tumors are very differential group of lesions. The most common symptoms are ophthalmology dysfunction as: exophthalmus, eye movement dysfunction and visual loss. More often a benign lesions is found than malignant. They are originated mostly from lacrimal glands. We present a case of 62 years old man with large expansion of benign tumor of the orbit with exophthalmus, eye movement disability and complete blindness. The authors performed radical surgery with removing of the orbit content. Histopathology described a very rare tumor of the orbit-hidradenoma.
- Published
- 2007
- Full Text
- View/download PDF
54. Metastatic hidradenocarcinoma with demonstration of Her-2/neu gene amplification by fluorescence in situ hybridization: potential treatment implications.
- Author
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Nash JW, Barrett TL, Kies M, Ross MI, Sneige N, Diwan AH, and Lazar AJ
- Subjects
- Adenoma, Sweat Gland drug therapy, Adenoma, Sweat Gland metabolism, Adenoma, Sweat Gland surgery, Adult, Antibodies, Monoclonal therapeutic use, Antibodies, Monoclonal, Humanized, Antineoplastic Agents therapeutic use, Axilla, Humans, Immunohistochemistry, Lymph Node Excision, Lymphatic Metastasis pathology, Male, Radiotherapy, Adjuvant, Sweat Gland Neoplasms genetics, Thoracic Wall, Trastuzumab, Adenoma, Sweat Gland genetics, Gene Amplification, Genes, erbB-2, In Situ Hybridization, Fluorescence, Lymphatic Metastasis genetics, Sweat Gland Neoplasms pathology
- Abstract
A 44-year-old man was referred for a right chest nodule of 3 months duration. A 'benign' nodule had been excised from this location 8 years prior. On examination, palpable nodes were noted in the right axilla. Radiographic studies were significant only for right axillary lymphadenopathy. Histologically, a nodular dermal proliferation composed of poorly differentiated epithelioid cells in nests and focally forming ducts with pseudopapillary architecture comprised the primary tumor. Features of a clear cell hidradenoma were noted focally. Immunohistochemical (IHC) analysis revealed reactivity for HMW cytokeratins, CK5 and CK7, p53, p63, CEA (focal), androgen receptor, EGFR, estrogen receptor (ER), MUC5AC, and strong/diffuse membranous staining for Her-2/neu. Negative stains included villin, TTF-1, CDX2, S-100 protein, vimentin, gross cystic disease fluid protein 15 (GCDFP-15), mammoglobulin, and MUC2. A wide local excision and axillary node dissection was performed. Metastatic tumor involved nine of 28 nodes. Interphase fluorescence in situ hybridization (FISH) demonstrated chromosomal amplification of the Her-2/neu locus within the tumor and a nodal metastasis. The patient has completed adjuvant and radiotherapy, including trastuzumab, and is asymptomatic. We believe this to be the first demonstration of Her-2/neu amplification in a malignant skin adnexal tumor. In analogy to breast carcinoma, these findings suggest the applicability of trastuzumab for patients with metastatic adnexal carcinomas demonstrating Her-2/neu amplification.
- Published
- 2007
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55. Giant apocrine hidradenoma of the breast.
- Author
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Knoedler D, Susnik B, Gonyo MB, and Osipov V
- Subjects
- Adenoma, Sweat Gland diagnostic imaging, Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Adult, Breast Neoplasms diagnostic imaging, Breast Neoplasms pathology, Breast Neoplasms surgery, Diagnosis, Differential, Female, Humans, Radiography, Sweat Gland Neoplasms diagnostic imaging, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Ultrasonography, Adenoma, Sweat Gland diagnosis, Breast Neoplasms diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
We report a case of a 26-year-old woman with an 8.0-cm tumor of the left breast. The tumor was clinically and radiologically suspicious for malignancy. The pathologic evaluation of the core biopsy and the subsequent excision specimen revealed a benign sclerosing, cystic, and papillary adnexal tumor with apocrine and clear cell morphology. The immunohistochemical staining for p63 was positive. Estrogen, progesterone, and Her-2 receptor immunohistochemical stains were negative. The cytogenetic analysis revealed 46, XX t(11:19) (q21;q13.1) balanced translocation. The final diagnosis was apocrine hidradenoma.
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- 2007
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56. [Atypical presentation of syringocystoadenoma papilliferum].
- Author
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Arias D, Castellano VM, Córdoba S, Miñano R, Martínez D, and Borbujo JM
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Adolescent, Astrocytoma, Female, Humans, Neoplasms, Second Primary pathology, Neoplasms, Second Primary surgery, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Thigh, Adenoma, Sweat Gland diagnosis, Neoplasms, Second Primary diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
Syringocystoadenoma papilliferum is benign adnexal tumor derived from the sweat glands that is located in the head and neck in 70-80% of patients, and commonly presents as a papule or a solitary nodule. We report a case of syringocystoadenoma papilliferum with an atypical presentation given its location in the thigh and the peculiar histologic features, unrepresentative of this entity.
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- 2006
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57. Mohs micrographic surgery for tubular apocrine adenoma.
- Author
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Martinelli PT, Cohen PR, Schulze KE, Tschen JA, and Nelson BR
- Subjects
- Aged, Apocrine Glands pathology, Cheek, Humans, Male, Treatment Outcome, Adenoma, Sweat Gland surgery, Apocrine Glands surgery, Mohs Surgery, Sweat Gland Neoplasms surgery
- Published
- 2006
- Full Text
- View/download PDF
58. Moll gland neoplasms of the eyelid: a clinical and pathological spectrum in 5 cases.
- Author
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Barker-Griffith AE, Streeten BW, and Charles NC
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Adult, Aged, Biomarkers, Tumor analysis, Eyelid Neoplasms chemistry, Eyelid Neoplasms surgery, Humans, Immunoenzyme Techniques, Male, Middle Aged, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Apocrine Glands pathology, Eyelid Neoplasms pathology, Sweat Gland Neoplasms pathology
- Published
- 2006
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59. Mohs micrographic surgery, sentinel lymph node mapping, and estrogen receptor analysis for the treatment of malignant nodular hidradenoma.
- Author
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Tolland JP, Brenn T, Guldbakke KK, and Schanbacher CF
- Subjects
- Aged, Biomarkers, Tumor metabolism, Diagnosis, Differential, Follow-Up Studies, Foot, Humans, Immunohistochemistry, Male, Sentinel Lymph Node Biopsy, Adenoma, Sweat Gland metabolism, Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Mohs Surgery methods, Receptors, Estrogen metabolism, Sweat Gland Neoplasms metabolism, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery
- Published
- 2006
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60. Syringocystadenoma papilliferum: a rare breast tumor in a young boy.
- Author
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Vaos G and Pierrakou P
- Subjects
- Adenoma, Sweat Gland surgery, Breast Neoplasms, Male surgery, Carcinoma, Ductal, Breast pathology, Child, Preschool, Diagnosis, Differential, Humans, Hyperplasia pathology, Male, Papilloma pathology, Adenoma, Sweat Gland pathology, Breast Neoplasms, Male pathology, Sweat Gland Neoplasms pathology
- Abstract
Syringocystadenoma papilliferum of the breast is extremely rare in children. However, some occasional cases have been diagnosed in females. This report documents a case of syringocystadenoma papilliferum occurring in a healthy 4-year-old male. Histopathologically, this tumor, located deep in the dermis, was characterized by the presence of papillary projections extending into the lumen of epithelial cystic invaginations in a background of dense fibrous tissue. The papillary projections and the duct-like structures were lined by an inner columnar epithelium, which demonstrated luminal apical decapitation secretion, and had an outer layer of smaller cuboidal cells. These findings support apocrine differentiation in this case. A fairly dense mononuclear infiltrate in the stroma of the tumor, especially in the papillary projections, was also present. Although syringocystadenoma papilliferum is rare in children, it should not be summarily ruled out during examinations of masses found in the pediatric male breast. It is important to recognize this unusual location of the tumor so that a prompt diagnosis, based on histopathology and surgical excision, can be proposed.
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- 2006
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61. Malignant hidradenoma: a report of two cases and review of the literature.
- Author
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Liapakis IE, Korkolis DP, Koutsoumbi A, Fida A, Kokkalis G, and Vassilopoulos PP
- Subjects
- Adenoma, Sweat Gland surgery, Aged, Humans, Lymphatic Metastasis, Male, Middle Aged, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
Introduction: Malignant tumors of the sweat glands are very rare. Clear cell hidradenoma is a lesion with histopathological features resembling those of eccrine poroma and eccrine spiradenoma. The biological behavior of the tumor is aggressive, with local recurrences reported in more than 50% of the surgically-treated cases., Materials and Methods: Two patients are presented, the first with tumor in the right axillary region, the second with a recurrent tumor of the abdominal wall. The first patient underwent wide excision with clear margins and axillary lymph node dissection and the second patient underwent wide excision of the primary lesion and bilateral inguinal node dissection due to palpable nodes., Results: The patients had uneventful postoperative courses. No additional treatment was administered. However, sixteen months after surgery, patient 2 developed extensive and massive recurrence involving almost the whole abdominal wall. Although he had received several chemotherapeutic agents, the disease had a relentless course and the patient succumbed two and a half years following surgery., Conclusion: Malignant tumors of the sweat glands are very rare neoplasms with no discrete clinical characteristics. It is necessary to suspect any lesion which shows evidence of enlargement and to verify its status by histological evaluation. Additional resection is generally required, with at least 2-cm clear margins, since surgery is the only effective treatment.
- Published
- 2006
62. Benign mixed tumour of the vulva.
- Author
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Soh HC, Russell P, and Dalrymple C
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Adult, Bartholin's Glands, Biomarkers, Tumor analysis, Diagnosis, Differential, Female, Humans, Immunohistochemistry, Neoplasms, Germ Cell and Embryonal chemistry, Neoplasms, Germ Cell and Embryonal surgery, Treatment Outcome, Vaginal Smears, Vulvar Neoplasms chemistry, Vulvar Neoplasms surgery, Adenoma, Sweat Gland pathology, Neoplasms, Germ Cell and Embryonal pathology, Vulvar Neoplasms pathology
- Published
- 2005
- Full Text
- View/download PDF
63. Clear-cell hidradenoma of the forearm in a young boy.
- Author
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Ozawa T, Fujiwara M, Nose K, and Muraoka M
- Subjects
- Adenoma, Sweat Gland surgery, Child, Preschool, Forearm, Humans, Male, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
We treated a 5-year-old boy with clear-cell hidradenoma of the forearm. Our literature search found only one previous report of this disease occurring during the first decade of life, and the present patient is the first with involvement of the limbs. This presentation demonstrates that clear-cell hidradenoma needs to be considered in the differential diagnosis of cutaneous tumors even in young children, which is of interest because malignant transformation can occur.
- Published
- 2005
- Full Text
- View/download PDF
64. Clear cell hidradenoma: a mimic of metastatic clear cell tumors.
- Author
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Volmar KE, Cummings TJ, Wang WH, Creager AJ, Tyler DS, and Xie HB
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Axilla, Biomarkers, Tumor analysis, Carcinoma, Renal Cell secondary, Carcinoma, Renal Cell surgery, Diagnosis, Differential, Humans, Immunohistochemistry, Kidney Neoplasms surgery, Lymph Nodes pathology, Lymph Nodes surgery, Male, Middle Aged, Mitotic Index, Neoplasm Metastasis diagnosis, Neoplasms, Multiple Primary chemistry, Neoplasms, Multiple Primary surgery, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Treatment Outcome, Adenoma, Sweat Gland diagnosis, Carcinoma, Renal Cell diagnosis, Kidney Neoplasms diagnosis, Neoplasms, Multiple Primary diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma. Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma. Furthermore, immunohistochemical studies can aid in distinguishing the 2 tumors. Knowing the cytologic features of primary skin adnexal neoplasms helps distinguish them from cutaneous metastases, which are more commonly referred for fine-needle aspiration biopsy evaluation. Detailed clinical history, physical findings, and ancillary studies are essential for correct diagnosis and categorization of these tumors. We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease.
- Published
- 2005
- Full Text
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65. Brooke-Spiegler syndrome: report of a case with combined lesions containing cylindromatous, spiradenomatous, trichoblastomatous, and sebaceous differentiation.
- Author
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Kazakov DV, Soukup R, Mukensnabl P, Boudova L, and Michal M
- Subjects
- Adenoma, Sweat Gland metabolism, Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Aged, Biomarkers, Tumor metabolism, Carcinoma, Adenoid Cystic metabolism, Carcinoma, Adenoid Cystic pathology, Carcinoma, Adenoid Cystic surgery, Carcinoma, Skin Appendage metabolism, Carcinoma, Skin Appendage surgery, Hair Diseases metabolism, Hair Diseases pathology, Hair Diseases surgery, Hair Follicle metabolism, Hair Follicle pathology, Humans, Immunoenzyme Techniques, Male, Sebaceous Glands metabolism, Sebaceous Glands pathology, Skin Neoplasms metabolism, Skin Neoplasms surgery, Syndrome, Carcinoma, Skin Appendage pathology, Neoplasms, Multiple Primary pathology, Neoplastic Syndromes, Hereditary pathology, Skin Neoplasms pathology
- Abstract
Brooke-Spiegler syndrome is an autosomal dominantly inherited disease with predisposition to cutaneous adnexal neoplasms, most commonly cylindromas and trichoepitheliomas. We report a patient in whom 11 lesions were removed from the scalp and face for various reasons over a period of 3 years. The histopathological survey revealed a plethora of benign adnexal neoplasms showing apocrine, follicular, and sebaceous differentiation occurring independently and conjointly. The histopathological spectrum in our patient included cylindromas, spiradenomas, trichoepitheliomas, small nodular trichoblastomas, and lymphadenomas. Many lesions had hybrid features of two or more neoplasms. By far the most common composite tumor was spiradenocylindroma. Some spiradenocylindromas demonstrated prominent sebaceous or trichoblastomatous differentiation or both. We suggest the terms "sebaceous spiradenocylindroma" and "trichospiradenocylindroma" for these lesions. The occurrence of sebaceous and trichoblastic differentiation in spiradenocylindromas is a further proof that spiradenoma and cylindroma are not eccrine tumors but neoplasms of the folliculosebaceousapocrine unit.
- Published
- 2005
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66. Sebaceous carcinoma, basal cell carcinoma, trichoadenoma, trichoblastoma, and syringocystadenoma papilliferum arising within a nevus sebaceus.
- Author
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Miller CJ, Ioffreda MD, and Billingsley EM
- Subjects
- Adenocarcinoma, Sebaceous complications, Adenocarcinoma, Sebaceous pathology, Adenocarcinoma, Sebaceous surgery, Adenoma, Sweat Gland complications, Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Carcinoma, Basal Cell complications, Carcinoma, Basal Cell pathology, Carcinoma, Basal Cell surgery, Diagnosis, Differential, Female, Humans, Middle Aged, Neoplasms, Multiple Primary complications, Neoplasms, Multiple Primary pathology, Neoplasms, Multiple Primary surgery, Nevus complications, Nevus pathology, Nevus surgery, Scalp, Sebaceous Gland Neoplasms complications, Sebaceous Gland Neoplasms diagnosis, Sebaceous Gland Neoplasms pathology, Sebaceous Gland Neoplasms surgery, Skin Neoplasms complications, Skin Neoplasms pathology, Skin Neoplasms surgery, Sweat Gland Neoplasms complications, Sweat Gland Neoplasms diagnosis, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Adenocarcinoma, Sebaceous diagnosis, Adenoma, Sweat Gland diagnosis, Carcinoma, Basal Cell diagnosis, Neoplasms, Multiple Primary diagnosis, Nevus diagnosis, Skin Neoplasms diagnosis
- Abstract
Background: Nevus sebaceus has a well-documented potential to develop a wide variety of neoplasms of both epidermal and adnexal origins. It is highly unusual for more than three tumors to arise simultaneously within a single nevus sebaceus. Sebaceous carcinoma arising within a nevus sebaceus is a rare occurrence., Objective: The objective was to report the case of a patient with a nevus sebaceus that simultaneously developed five distinct neoplasms of epidermal and various adnexal origins and to report the fourth case of sebaceous carcinoma arising within a nevus sebaceus., Methods: A 45-year-old woman presented with a nevus sebaceus that contained five separate neoplasms, including sebaceous carcinoma, basal cell carcinoma, trichoadenoma, trichoblastoma, and syringocystadenoma papilliferum., Results: Complete excision of the nevus sebaceus and the five tumors was performed. Systemic work-up showed no evidence of metastatic disease or association with Muir-Torre syndrome., Conclusion: This case report highlights the diverse neoplastic potential of nevus sebaceus and demonstrates the capacity of this hamartoma to develop aggressive tumors, such as sebaceous carcinoma. Prophylactic excision or at least close clinical surveillance for sudden development of new growths is warranted in all cases of nevus sebaceus.
- Published
- 2004
- Full Text
- View/download PDF
67. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands.
- Author
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Nishie W, Sawamura D, Mayuzumi M, Takahashi S, and Shimizu H
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Anal Canal pathology, Biomarkers, Tumor analysis, Female, Genitalia, Female pathology, Humans, Immunohistochemistry, Mammary Glands, Human pathology, Middle Aged, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Treatment Outcome, Adenoma, Sweat Gland pathology, Apocrine Glands pathology, Sweat Gland Neoplasms pathology
- Abstract
A case of hidradenoma papilliferum with mixed features of syringocystadenoma papilliferum (SCAP) and anogenital mammary-like glands is reported. A single, fresh red-colored nodule developed in the sulcus between the labia majora and minora of a 49-year-old Japanese woman. Histopathologically, the tumor showed epithelial lining with apocrine secretion and slight connective tissues characteristics. Our case was unique because, like SCAP, the tumor was connected to the epidermis and cystic invaginations extended downward into the deep dermis. In addition, beneath the tumor, tubular structures that resembled normal mammary tissue were present in the subcutaneous fatty tissue. In this study, it has been suggested that this tumor might have been developed from these mammary-like glands.
- Published
- 2004
- Full Text
- View/download PDF
68. Spiradenocarcinoma of the breast arising in a long-standing spiradenoma.
- Author
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Ribeiro-Silva A, Shaletich C, Careta RS, Kazava DK, Siqueira MC, and Ponton F
- Subjects
- Adenoma, Sweat Gland metabolism, Adenoma, Sweat Gland surgery, Biomarkers, Tumor metabolism, Breast Neoplasms metabolism, Breast Neoplasms surgery, Carcinoma, Skin Appendage metabolism, Carcinoma, Skin Appendage surgery, Female, Humans, Immunohistochemistry, Keratins metabolism, Mastectomy, Middle Aged, Mucin-1 metabolism, Neoplasms, Second Primary metabolism, Neoplasms, Second Primary surgery, Sweat Gland Neoplasms metabolism, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Breast Neoplasms pathology, Carcinoma, Skin Appendage pathology, Neoplasms, Second Primary pathology, Sweat Gland Neoplasms pathology
- Abstract
The embryologic origin of the breast is related to salivary and sweats glands. Thus, breast neoplasms may show differentiation toward these tissues, although this is a rare event in humans. We report the clinicopathologic and immunohistochemical features of a 57-year-old woman presenting with a spiradenoma that originated in breast tissue and became malignant 40 years later. Some histogenetic concepts relevant to this case are discussed, along with a brief review of this neoplasm.
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- 2004
- Full Text
- View/download PDF
69. Adjacent dermal nodules on the nose--case.
- Author
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Ravenscroft J, Leach I, and Varma S
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Aged, Aged, 80 and over, Diagnosis, Differential, Humans, Male, Nose, Skin Neoplasms pathology, Skin Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Skin Neoplasms diagnosis
- Published
- 2004
- Full Text
- View/download PDF
70. Syringocystadenocarcinoma papilliferum: successfully treated with Mohs micrographic surgery.
- Author
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Chi CC, Tsai RY, and Wang SH
- Subjects
- Humans, Male, Middle Aged, Remission Induction, Adenoma, Sweat Gland surgery, Ear Neoplasms surgery, Ear, External, Mohs Surgery, Sweat Gland Neoplasms surgery
- Abstract
Background: Syringocystadenocarcinoma papilliferum, a rare sweat gland carcinoma, is the malignant counterpart of syringocystadenoma papilliferum., Objective: To demonstrate a rare case of syringocystadenocarcinoma papilliferum successfully treated with Mohs micrographic surgery., Methods: A 60-year-old male presented with two verrucous plaques on his right auricle since childhood. These two plaques became ulcerated, more painful, and pruritic in 1 year. Histopathologic examination revealed syringocystadenocarcinoma papilliferum., Results: Mohs micrographic surgery with reconstruction of right auricle was performed subsequently. There are no signs of recurrence or metastasis 6 years after operation., Conclusion: Syringocystadenocarcinoma papilliferum can be successfully treated with Mohs micrographic surgery.
- Published
- 2004
- Full Text
- View/download PDF
71. [Hidradenoma of external ear].
- Author
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Gierek T, Zbrowska-Bielska D, Smółka W, Kajor M, and Witkowska M
- Subjects
- Adenoma, Sweat Gland surgery, Diagnosis, Differential, Ear Neoplasms surgery, Ear, External surgery, Female, Humans, Middle Aged, Neoplasm Invasiveness, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Ear Neoplasms pathology, Ear, External pathology, Sweat Gland Neoplasms pathology
- Abstract
The authors present a rare case of hidradenoma of the external ear and discussed the clinical picture, as well as diagnostic and therapeutic procedures.
- Published
- 2004
72. Eccrine spiradenoma of the ear: case report.
- Author
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Amoroso C, Grandi E, and Carinci F
- Subjects
- Adenoma, Sweat Gland surgery, Aged, Ear Neoplasms surgery, Ear, External surgery, Female, Humans, Adenoma, Sweat Gland pathology, Ear Neoplasms pathology, Ear, External pathology
- Abstract
A case of eccrine spiradenoma of the left pinna is described. To the best of our knowledge, this is the first report regarding this site. The treatment was a surgical excision in safe margins. This rare benign tumour should be considered for the differential diagnosis of solitary or multiple soft tissue lesions of the head and neck.
- Published
- 2003
- Full Text
- View/download PDF
73. Coexpression of S-100 and smooth muscle actin in nodular hidradenoma.
- Author
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Vodovnik A
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Adult, Biomarkers, Tumor analysis, Female, Humans, Immunohistochemistry, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Treatment Outcome, Actins metabolism, Adenoma, Sweat Gland metabolism, S100 Proteins metabolism, Sweat Gland Neoplasms metabolism
- Published
- 2003
- Full Text
- View/download PDF
74. A case of porocarcinoma from pre-existing hidroacanthoma simplex: need of early excision for hidroacanthoma simplex?
- Author
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Lee JB, Oh CK, Jang HS, Kim MB, Jang BS, and Kwon KS
- Subjects
- Abdomen, Acrospiroma surgery, Adenoma, Sweat Gland surgery, Aged, Humans, Male, Neoplasms, Glandular and Epithelial surgery, Sweat Gland Neoplasms surgery, Acrospiroma pathology, Adenoma, Sweat Gland pathology, Cell Transformation, Neoplastic pathology, Neoplasms, Glandular and Epithelial pathology, Sweat Gland Neoplasms pathology
- Abstract
Background: Hidroacanthoma simplex (HAS) is an uncommon eccrine neoplasm of the skin. It is a benign neoplasm, but some cases of malignant change were reported in the literature., Objective: To describe a rare case of porocarcinoma in a relatively short period from pre-existing HAS on the abdomen., Methods: Wide local excision was performed on this neoplasm., Results: There was no recurrence for 72 months after wide excision. CONCLUSION. : We recommend an early excision and careful attention in the case of HAS because of its potential malignant change.
- Published
- 2003
- Full Text
- View/download PDF
75. Large ulcerated perianal hidradenoma papilliferum in a young female.
- Author
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Handa Y, Yamanaka N, Inagaki H, and Tomita Y
- Subjects
- Adenoma, Sweat Gland surgery, Adult, Anus Neoplasms surgery, Female, Humans, Adenoma, Sweat Gland pathology, Anus Neoplasms pathology
- Abstract
Background: Hidradenoma papilliferum is an uncommon benign tumor that is located almost exclusively in the vulvar and anal areas. It is usually very small and asymptomatic, and to make a correct diagnosis is clinically very difficult. Occasionally the tumor becomes elevated to form a reddish brown papillary mass, and the surface ulcerates, which may erroneously suggest malignancy., Objective: We report a case of a large, perianal hidradenoma papilliferum with suspected malignancy in a young Japanese female., Results: A 22-year-old female had been aware of a perianal nodule for approximately 1 year. Examination of the perianal area revealed a wide pedunculated, reddish nodule with several white maculae. It was ulcerated and bleeding, 2.0 x 1.2 x 0.8 cm in size, and located in the 3 o'clock position. The nodule was totally excised with a narrow margin. The histopathologic diagnosis was hidradenoma papilliferum. No recurrence was observed for 23 months., Conclusion: When dermatologists encounter tumors of the anogenital area of adult females, it is important to keep hidradenoma papilliferum in mind as the differential diagnosis. Dermatologists should recognize that the tumor is benign, eliminating the need for wide resection.
- Published
- 2003
- Full Text
- View/download PDF
76. Carcinoma and eccrine syringofibroadenoma: a report of five cases.
- Author
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Bjarke T, Ternesten-Bratel A, Hedblad M, and Rausing A
- Subjects
- Adenoma, Sweat Gland metabolism, Adenoma, Sweat Gland surgery, Aged, Aged, 80 and over, Biomarkers, Tumor metabolism, Carcinoma, Squamous Cell metabolism, Carcinoma, Squamous Cell surgery, Female, Humans, Immunohistochemistry, Male, Metaplasia, Neoplasms, Second Primary, Sweat Gland Neoplasms metabolism, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Carcinoma, Squamous Cell pathology, Sweat Gland Neoplasms pathology
- Abstract
Background: In the literature, there are some reports of cases interpreted as carcinomatous transformation in eccrine syringofibroadenoma (ESFA)., Results: We have studied five cases with a histological mixture of ESFA and carcinoma. The carcinoma had a partial squamous cell cytology in all cases. In two of them, there was partial poroma and porocarcinoma picture. However, the squamous cell parts had some features of porocarcinoma such as retiform configuration and funnel-like cavities with luminal carcinoembryonic antigen (CEA) positivity. Also, there was strong epithelial membrane antigen (EMA) positivity. Therefore, we interpret the cases as porocarcinomas with extensive squamous metaplasia. One case had a life-long precursor lesion with a histologic picture interpreted as ESFA, with progressing cytologic atypia. Another case had ectodermal dysplasia, a condition known to predispose to ESFA and a precursor lesion of long-standing, probably benign ESFA. In these two cases, we interpret the carcinoma as a secondary development in a benign ESFA. Three cases were otherwise healthy people with precursor lesions of 10-, 5-, and 2-year duration. We do not know for certain if the ESFA preceded the carcinoma in these cases but we think that it probably did., Conclusions: We recommend that diagnosed ESFA shall be completely excised or followed, in view of the risk of developing carcinoma.
- Published
- 2003
- Full Text
- View/download PDF
77. Low-grade malignant eccrine spiradenoma with systemic metastases.
- Author
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Leonard N, Smith D, and McNamara P
- Subjects
- Adenocarcinoma surgery, Biopsy, Fatal Outcome, Female, Humans, Middle Aged, Neoplasm Metastasis, Sweat Gland Neoplasms surgery, Adenocarcinoma secondary, Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Bone Neoplasms secondary, Sweat Gland Neoplasms pathology
- Abstract
Malignant eccrine spiradenoma (MES) is a very rare tumor. Tumors can be low grade or high grade. There are nine cases in the literature with systemic metastases. Of these, only one was low grade; the others had obvious features of high-grade malignancy such as pleomorphism, increased mitoses, and abnormal mitoses. Low grade MESs are more difficult to diagnose and are said to have a better prognosis. We report an additional case of low-grade MES with systemic metastases. It had a monotonous appearance with few mitotic figures and minimal pleomorphism. Vascular invasion was seen in both cases of low-grade MES and may be an important prognostic feature.
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- 2003
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78. Linear spiradenoma with focal malignant transformation.
- Author
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Braun-Falco M, Bonel H, Ring J, and Hein R
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Adult, Cell Transformation, Neoplastic, Diagnosis, Differential, Female, Humans, Leg, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
Malignant spiradenoma is an exceedingly rare adnexal tumour clinically characterized by rapid enlargement of a pre-existing, long-standing benign spiradenoma. Microscopic examination typically reveals a continuum between benign spiradenoma and areas of malignant transformation. Biological behaviour is unpredictable and it should be regarded as a potentially lethal neoplasm. Treatment recommendations require radical surgical excision. The reported case of a 23-year-old female illustrates the malignant transformation of a 1.5 cm nodule within a large linear spiradenoma almost covering the frontal aspect of the lower leg. In reviewing the literature, malignant transformation seems to occur slightly more often in multiple than in solitary spiradenomas. It is unclear whether excision restricted to the malignant area is an advisable treatment option in comparison to total excision of all spiradenoma nodules. In the presented case, the transformed area was excised. The patient is free of recurrence after 2 years.
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- 2003
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79. Malignant clear-cell hidradenoma associated with pseudoepitheliomatous hyperplasia on the forehead.
- Author
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Harada T, Muraoka M, Ishii M, and Wakasa K
- Subjects
- Adenoma, Sweat Gland surgery, Aged, Forehead pathology, Humans, Hyperplasia, Male, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland complications, Skin pathology, Sweat Gland Neoplasms complications
- Published
- 2003
- Full Text
- View/download PDF
80. Familial eccrine spiradenoma: a case report and review of the literature.
- Author
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Ter Poorten MC, Barrett K, and Cook J
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Adult, Aged, Female, Head and Neck Neoplasms pathology, Head and Neck Neoplasms surgery, Humans, Laser Therapy, Middle Aged, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland genetics, Head and Neck Neoplasms genetics, Sweat Gland Neoplasms genetics
- Abstract
Background: Familial eccrine spiradenoma is a rare autosomal dominant condition that is characterized by slow-growing, benign adnexal tumors., Objective: We investigated a case of familial eccrine spiradenoma displaying an autosomal dominant inheritance pattern. To our knowledge, only two previously reported cases of familial eccrine spiradenoma exist in the literature., Methods: A case report and review of the literature are given., Results: We report a case of familial eccrine spiradenoma in a mother and daughter and present successful treatment using surgical extirpation and CO2 laser ablation., Conclusion: Familial eccrine spiradenoma is a benign autosomal dominantly inherited condition that is characterized by tender, slow-growing, adnexal tumors of the head and neck. Surgical tumor extirpation and CO2 laser ablation offer both an effective symptomatic and cosmetically elegant treatment option.
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- 2003
- Full Text
- View/download PDF
81. Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor.
- Author
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Hsu PJ, Liu CH, and Huang CJ
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Adult, Biomarkers, Tumor chemistry, Carcinoma, Verrucous chemistry, Carcinoma, Verrucous surgery, Cystadenoma, Papillary chemistry, Cystadenoma, Papillary surgery, Humans, Immunohistochemistry, Male, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Carcinoma, Verrucous pathology, Cystadenoma, Papillary pathology, Sweat Gland Neoplasms pathology
- Abstract
Tubulopapillary hidradenoma (TPH)1 is a term proposed to describe morphological dermal ductal tumors with both eccrine and apocrine differentiation. The term TPH encompasses a spectrum of lesions that includes tubular apocrine adenoma (TAA) and papillary eccrine adenoma (PEA):2 PEA and TAA can be indistinguishable both clinically and histologically. We described a case of TPH with both prominent eccrine and apocrine differentiation combined with syringocystadenoma papilliferum (SCAP) over the distal extremity. This rarely encountered dermatopathological phenomenon is the sixth reported case from the literature in which PEA or TAA and SCAP were present in the same lesion.3-7 Furthermore, the tumor had a warty surface, which is histologically consistent with a typical viral verruca. Although PCR and DNA probe hybridization for human papilloma virus (HPV) types 2, 6/11, 16 and 18 failed to reveal positive results, the location and clinicopathologic correlation convinced us that superimposed HPV could not be excluded.
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- 2003
- Full Text
- View/download PDF
82. Hidradenoma papilliferum of nasal skin.
- Author
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Smith FB, Shemen LJ, Guerrieri C, and Ismail SS
- Subjects
- Adenocarcinoma, Papillary diagnosis, Adenoma, Sweat Gland surgery, Adult, Diagnosis, Differential, Humans, Male, Nasal Mucosa pathology, Neoplasm Recurrence, Local, Nose Neoplasms surgery, Papilloma diagnosis, Skin Neoplasms surgery, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Nose Neoplasms diagnosis, Skin Neoplasms diagnosis, Sweat Gland Neoplasms diagnosis
- Abstract
Pathologic examination of an excisional biopsy specimen of a subepidermal nodule from the nasal tip of a 37-year-old black man demonstrated papillae covered by eosinophilic columnar epithelial cells, suggesting cylindric cell papilloma or well-differentiated papillary adenocarcinoma of nasal mucosa. The patient did not submit to further investigation of the sinonasal tract but sought attention 15 months later because of local recurrence of the lesion. A protuberant, 3-cm, cystic nodule of the subcutis over the left nasal ala and tip was excised completely and found to have characteristics of hidradenoma papilliferum, an apocrine gland neoplasm most commonly occurring in the anogenital skin of white women. This case demonstrates how easily an apocrine neoplasm arising near a mucocutaneous junction can be confused with a mucosal tumor, potentially leading to inappropriate treatment.
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- 2003
- Full Text
- View/download PDF
83. Pathologic quiz case: an enlarging, firm nodule on the abdominal skin in an otherwise healthy 73-year-old woman.
- Author
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Sellheyer K, Soltani K, and Shea CR
- Subjects
- Abdomen, Adenoma, Sweat Gland surgery, Aged, Female, Humans, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Skin pathology, Sweat Gland Neoplasms diagnosis
- Published
- 2003
- Full Text
- View/download PDF
84. Eccrine syringofibroadenoma arising in peristomal skin: a report of two cases.
- Author
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Clarke LE, Ioffreda M, and Abt AB
- Subjects
- Adenoma, Sweat Gland complications, Adenoma, Sweat Gland surgery, Aged, Female, Fibroadenoma complications, Fibroadenoma surgery, Humans, Male, Middle Aged, Neoplasm Recurrence, Local surgery, Postoperative Complications, Sweat Gland Neoplasms complications, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Eccrine Glands pathology, Enterostomy adverse effects, Fibroadenoma pathology, Sweat Gland Neoplasms pathology
- Abstract
Eccrine syringofibroadenoma (ESFA) is a benign neoplasm arising from the intraepidermal portion of eccrine ducts. It is characterized by a distinctive histologic pattern of epithelial cells arranged in anastomosing cords surrounded by a fibrovascular stroma. Approximately 50 cases of ESFA have been reported, and in recent years the lesion has been described occurring in association with other skin conditions. We report 2 cases of ESFA arising in abdominal skin adjacent to enterostomy sites.
- Published
- 2003
- Full Text
- View/download PDF
85. Vulvar poroid hidradenoma.
- Author
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Alowami SO, Malik A, and Hanna W
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Biomarkers, Tumor analysis, Carcinoembryonic Antigen analysis, Female, Glycogen analysis, Humans, Middle Aged, Mucin-1 analysis, Periodic Acid-Schiff Reaction, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Vulvar Neoplasms chemistry, Vulvar Neoplasms surgery, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology, Vulvar Neoplasms pathology
- Published
- 2002
- Full Text
- View/download PDF
86. Malignant eccrine spiradenoma occurring on a traumatized area.
- Author
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Arslan E, Unal S, Cinel L, Demirkan F, and Cin I
- Subjects
- Adenoma, Sweat Gland surgery, Biopsy, Diagnosis, Differential, Female, Humans, Lymph Node Excision, Lymph Nodes pathology, Middle Aged, Neoplasm Recurrence, Local pathology, Neoplasm Recurrence, Local surgery, Reoperation, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Cell Transformation, Neoplastic pathology, Sweat Gland Neoplasms pathology, Thigh injuries, Wounds, Penetrating pathology
- Published
- 2002
- Full Text
- View/download PDF
87. Malignant eccrine spiradenoma.
- Author
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Mirza I, Kloss R, and Sieber SC
- Subjects
- Adenoma, Sweat Gland drug therapy, Adenoma, Sweat Gland surgery, Aged, Humans, Immunohistochemistry, Lymph Node Excision, Lymph Nodes pathology, Lymphatic Metastasis pathology, Male, Receptors, Estrogen analysis, Selective Estrogen Receptor Modulators therapeutic use, Sweat Gland Neoplasms drug therapy, Sweat Gland Neoplasms surgery, Tamoxifen therapeutic use, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
Malignant transformation of eccrine spiradenoma is extremely rare. We describe the case of a 70-year-old man with malignant eccrine spiradenoma of the forearm and metastases to the axillary lymph nodes. Surgical excision with adequate margins and lymph node dissection was performed. Tamoxifen therapy was instituted after obtaining positive immunostaining results for estrogen receptor. After 41 months of follow-up, there has been no recurrence or distant metastases. Wide local excision and close follow-up are crucial in the management of malignant eccrine spiradenoma. The role of other therapeutic modalities, including hormonal therapy, remains to be determined.
- Published
- 2002
- Full Text
- View/download PDF
88. Trichilemmoma and syringocystadenoma papilliferum arising in naevus sebaceous.
- Author
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Castilla EA, Bergfeld WF, and Ormsby A
- Subjects
- Adenoma, Sweat Gland surgery, Adolescent, Humans, Male, Neoplasms, Basal Cell surgery, Neoplasms, Multiple Primary surgery, Nevus surgery, Skin Neoplasms surgery, Adenoma, Sweat Gland pathology, Neoplasms, Basal Cell pathology, Neoplasms, Multiple Primary pathology, Nevus pathology, Skin Neoplasms pathology
- Published
- 2002
- Full Text
- View/download PDF
89. Multiple eccrine spiradenomas on the hand, forearm and head.
- Author
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Ohtsuka H, Tezuka K, Kumakiri M, and Ohtsuki Y
- Subjects
- Adenoma, Sweat Gland diagnosis, Adenoma, Sweat Gland surgery, Biopsy, Needle, Female, Follow-Up Studies, Forearm, Hand, Humans, Immunohistochemistry, Microscopy, Electron, Middle Aged, Risk Assessment, Scalp, Skin ultrastructure, Sweat Gland Neoplasms diagnosis, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
The first case of multifocal eccrine spiradenomas on the hand, forearm and scalp is described. This case is unusual in that the tumors located on the little finger included the nail matrix and occurred in a linear/zosteriform distribution, resulting in a nail deformity. The nodules on the forearm and scalp were in a random distribution. Histologically, each tumor was highly cellular and composed of two cell types: small darkly staining basaloid cells and larger, pale cells. Ultrastructural observations often showed an intracellular lumen with numerous microvilli in larger pale-staining cells., (Copyright 2002 S. Karger AG, Basel)
- Published
- 2002
- Full Text
- View/download PDF
90. [Cylindrospiradenomas in Brooke-Spiegler syndrome].
- Author
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Braun-Falco M, Hein R, and Ring J
- Subjects
- Adenoma surgery, Adenoma, Sweat Gland surgery, Head and Neck Neoplasms surgery, Humans, Male, Middle Aged, Neoplasms, Basal Cell surgery, Neoplasms, Multiple Primary surgery, Skin pathology, Skin Neoplasms surgery, Sweat Gland Neoplasms surgery, Syndrome, Terminology as Topic, Adenoma pathology, Adenoma, Sweat Gland pathology, Head and Neck Neoplasms pathology, Neoplasms, Basal Cell pathology, Neoplasms, Multiple Primary pathology, Skin Neoplasms pathology, Sweat Gland Neoplasms pathology
- Abstract
Brooke-Spiegler syndrome is a rare autosomal-dominant inherited disease, characterized by the development of multiple cylindromas and trichoepitheliomas. We report a case in which tumors were found on the head showing histological features of both cylindromas and spiradenomas. These changes were in continuity within the same lesions. Since cylindromas are thought to be apocrine in nature, whereas spiradenomas are eccrine, a contiguous growth within the same neoplasm indicates a conflict concerning their histogenesis. The available histological, ultrastructural and immunohistochemical studies have not produced any criteria to allow an unequivocal classification, suggesting instead that both tumors arise from similarly differentiated cells, perhaps from pluripotent epithelial cells. In our opinion, it seems impractical to strictly classify cylindromas and spiradenomas into tumors of apocrine or eccrine differentiation. Moreover, at least for those cases of Brooke-Spiegler syndrome, where both tumors are found in immediate vicinity to each other, we propose the term cylindrospiradenoma.
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- 2001
- Full Text
- View/download PDF
91. Malignant mixed tumor ex eccrine spiradenoma: an unusual pattern of malignant dedifferentiation.
- Author
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Lara JF, Nadeem MA, and Asaadi M
- Subjects
- Adenoma, Sweat Gland chemistry, Adenoma, Sweat Gland surgery, Aged, Antigens, Neoplasm analysis, Biomarkers, Tumor analysis, Humans, Immunohistochemistry, Male, Neoplasms, Second Primary chemistry, Neoplasms, Second Primary surgery, Radiotherapy, Adjuvant, Sweat Gland Neoplasms chemistry, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Cell Transformation, Neoplastic, Neoplasms, Second Primary pathology, Sweat Gland Neoplasms pathology
- Abstract
Eccrine spiradenoma (ES) is a benign tumor of the skin adnexal origin. It is often seen in the head and neck region of young adults and may be present for years. While there have been numerous case reports of malignant degeneration within ES, they have been mostly carcinomatous dedifferentiation and rarely carcinosarcomas. A malignant mixed tumor is a neoplasm with a malignant epithelial component and areas of chondroid and myxoid differentiation within the malignant epithelial proliferation. While the epithelial component is malignant, the mesenchymal component is felt to represent a benign, metaplastic response of the stroma. While the malignant mixed tumor has a benign counterpart, the benign mixed tumor, the former is usually not seen in continuity with the latter. We describe a case of ES with malignant degeneration and demonstrate the transformation from benign to malignant. The histology and immunohistochemistry of the neoplasm supports a malignant mixed tumor, an extremely unusual neoplasm to see in association with ES or any benign adnexal neoplasm.
- Published
- 2001
- Full Text
- View/download PDF
92. De novo malignant eccrine spiradenoma with an interesting and unusual location.
- Author
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Yildirim S, Aköz T, Akan M, and Ege GA
- Subjects
- Adenocarcinoma drug therapy, Adenocarcinoma secondary, Adenoma, Sweat Gland surgery, Colonic Neoplasms secondary, Humans, Liver Neoplasms drug therapy, Liver Neoplasms secondary, Male, Middle Aged, Neoplasms, Multiple Primary, Nose Neoplasms surgery, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Nose Neoplasms pathology, Sweat Gland Neoplasms pathology
- Abstract
Background: Reports in the literature reveal that malignant eccrine spiradenomas (MES) are exceedingly rare, and represent aggressive tumors arising in long-standing benign eccrine spiradenomas (ES)., Objective: We present a de novo case of MES of the nose, in contrast to reports in the literature of progression from long-standing benign lesions., Methods: Case report and brief review of the literature., Results: Our case was accepted as de novo MES because there was no evidence of ES on pathologic examination. It was treated by surgical excision with 1 cm tumor-free margins. No recurrence or complications were observed for 2 months, but long-term follow-up could not be performed because the patient died of adenocarcinoma of the colon., Conclusion: Although previously reported lesions have arisen in long-standing benign ESs, usually on the trunk or extremities, this report shows that MES may occur as a primary malignant tumor and may occur in unusual locations such as the nose.
- Published
- 2001
- Full Text
- View/download PDF
93. The efficacy of electrosurgery and excision in treating patients with multiple apocrine hidrocystomas.
- Author
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Gupta S, Handa U, Handa S, and Mohan H
- Subjects
- Adenoma, Sweat Gland pathology, Apocrine Glands pathology, Hidrocystoma pathology, Humans, Male, Middle Aged, Neoplasms, Multiple Primary pathology, Adenoma, Sweat Gland surgery, Electrosurgery, Hidrocystoma surgery, Neoplasms, Multiple Primary surgery
- Abstract
Background: Apocrine hidrocystomas are adenomatous cystic proliferations of the apocrine glands. They typically occur as solitary lesions, though rarely may occur as multiple lesions. Management of multiple hidrocystomas can be difficult, particularly if they are large. Surgical modalities may be required for effective therapy., Objective: To compare the results of electrosurgery and excision in treating multiple apocrine hidrocystomas., Methods: A 50-year-old man presented with multiple apocrine hidrocystomas ranging in size from 1 to 12 mm. The lesions were located over the periorbital skin, cheeks, and pinnae. Excision and electrodessication were utilized for therapy. At a 1-year follow-up, the patient was evaluated for recurrences and cosmetic result., Results: There were no recurrences until 1 year after surgery. In the areas treated with electrodessication, no visible scars were identified. In the areas treated with excision, localized scars were observed., Conclusions: Both electrodessiation and excision are effective therapies for multiple apocrine hidrocystomas. We suggest that tumors less than 1 cm be treated with electrodessication and lesions greater than 1 cm with excision.
- Published
- 2001
- Full Text
- View/download PDF
94. Multiple linear eccrine spiradenomas with eyelid involvement.
- Author
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Gupta S, Radotra BD, Kaur I, Handa S, and Kumar B
- Subjects
- Adenoma, Sweat Gland surgery, Adult, Biopsy, Needle, Female, Follow-Up Studies, Humans, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland pathology, Eyelids, Sweat Gland Neoplasms pathology
- Abstract
Eccrine spiradenoma is an uncommon tumour of the sweat gland and usually occurs as a solitary small painful nodule. Very rarely, it may present as multiple tumours arranged in a linear/zosteriform fashion. We present the case of a 23-year-old female who had multiple spiradenomas arranged linearly from the midline of forehead to the left corner of the mouth and a few lesions also on the margin of the left eyelid. The lesions were probably along the Blaschko's lines. Tumours were excised surgically in stages. Literature search revealed only 13 reported cases of linear/zosteriform/naevoid multiple spiradenomas and only four cases of solitary spiradenoma of the eyelid. The review of reported cases suggests that arrangement of tumours in a linear/zosteriform pattern is an important diagnostic clue for multiple (naevoid) spiradenomas.
- Published
- 2001
- Full Text
- View/download PDF
95. Eccrine syringofibroadenoma: case report and review of the literature.
- Author
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Takeda H, Mitsuhashi Y, Hayashi M, and Kondo S
- Subjects
- Adenoma, Sweat Gland surgery, Biopsy, Needle, Follow-Up Studies, Humans, Male, Middle Aged, Sweat Gland Neoplasms surgery, Treatment Outcome, Adenoma, Sweat Gland pathology, Sweat Gland Neoplasms pathology
- Abstract
Eccrine syringofibroadenoma (ESFA) is a rare disorder that shows differentiation toward eccrine sweat apparatus. There is a controversy concerning the pathogenesis and differentiation of this tumour. We report a case of ESFA in a 63-year-old Japanese man. We review the literature presenting a classification, including a newly reported subtype. Clinically and pathogenically, ESFA is probably a group of heterogeneous disorders.
- Published
- 2001
- Full Text
- View/download PDF
96. Commentary on malignant eccrine spiradenoma.
- Author
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Ratner D
- Subjects
- Adenoma, Sweat Gland surgery, Adenoma, Sweat Gland therapy, Humans, Sweat Gland Neoplasms surgery, Sweat Gland Neoplasms therapy, Adenoma, Sweat Gland diagnosis, Sweat Gland Neoplasms diagnosis
- Published
- 2001
97. Distal arteriovenous fistula to maintain patency of the venous drainage of a latissimus dorsi flap following subclavian vein repair.
- Author
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Har-Shai Y, Karmeli R, Saute M, Mayblum S, Taran A, Barak A, Loberman Z, Naveh U, Eyal A, and Schramek A
- Subjects
- Adenoma, Sweat Gland blood supply, Axillary Vein surgery, Brachial Artery surgery, Humans, Male, Middle Aged, Skin Neoplasms blood supply, Thoracic Neoplasms blood supply, Adenoma, Sweat Gland surgery, Arteriovenous Shunt, Surgical, Skin Neoplasms surgery, Subclavian Vein surgery, Surgical Flaps blood supply, Thoracic Neoplasms surgery, Vascular Patency physiology
- Abstract
Successful reconstructive surgery with muscle flaps depends on adequate arterial supply and undisturbed venous drainage. Combining such surgery with reconstructive vascular surgery of a large-caliber vein that is responsible for the venous drainage of the flap poses an additional challenge--the repaired vein's susceptibility to thrombosis. Every attempt must be made to prevent venous outflow obstruction following muscle flap surgery. Data from the vascular surgery literature demonstrate a low success rate for subclavian vein repair. The success rate with venous reconstructive surgery has been greater when a distal arteriovenous fistula accompanied the repair. The present case described the use of a temporary distal cephalic-brachial arteriovenous fistula to maintain the patency of the venous drainage of a pedicled latissimus dorsi muscle flap, following subclavian vein repair, for one-stage coverage of a large chest wall defect.
- Published
- 2001
- Full Text
- View/download PDF
98. [Middle ear adenoma. Long-term course of a rare neoplasm].
- Author
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Zeise K, Kaschke O, and Jautzke G
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Cholesteatoma, Middle Ear diagnosis, Cholesteatoma, Middle Ear pathology, Cholesteatoma, Middle Ear surgery, Ear Neoplasms pathology, Ear Neoplasms surgery, Female, Follow-Up Studies, Humans, Middle Aged, Adenoma, Sweat Gland diagnosis, Ear Neoplasms diagnosis, Ear, Middle pathology, Ear, Middle surgery
- Abstract
Adenomas of the middle ear are rare benign glandular neoplasms arising from the middle ear mucosa. After previous operations 25 and 15 years before, a 67-year-old female complained about dizziness, tinnitus, and unilateral hearing loss on the left side. A tumor in the tympanum that was revealed by otoscopy could be removed completely. Histological examinations showed an adenoma of the middle ear with cholesteatoma. This was inconsistent with the histological result of the operation in 1983, which had described a hidradenoma. An exact analysis of the preparations confirmed that a middle ear adenoma had already been present in 1983. Hidradenoma is one of the most important differential diagnoses. The characteristic histological sign of middle ear adenomas in contrast to hidradenomas is the lack of myoepithelial cells. In addition, it is very difficult to differentiate middle ear adenoma and adenocarcinoma using histopathological and clinical methods. Therefore, thorough follow-up is mandatory for patients after surgical treatment of middle ear adenomas.
- Published
- 2001
- Full Text
- View/download PDF
99. Solitary ulcerated nodule on the leg.
- Author
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Neuhaus IM, Hassanein AM, and Skidmore RA
- Subjects
- Adenoma, Sweat Gland pathology, Adenoma, Sweat Gland surgery, Aged, Diagnosis, Differential, Female, Humans, Leg, Sweat Gland Neoplasms pathology, Sweat Gland Neoplasms surgery, Adenoma, Sweat Gland diagnosis, Sweat Gland Neoplasms diagnosis
- Published
- 2000
- Full Text
- View/download PDF
100. Vulvar hidradenoma papilliferum. A review of 10.5 years' experience.
- Author
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Virgili A, Marzola A, and Corazza M
- Subjects
- Adenoma, Sweat Gland surgery, Biopsy, Female, Humans, Retrospective Studies, Vulvar Neoplasms surgery, Adenoma, Sweat Gland pathology, Vulvar Neoplasms pathology
- Abstract
Objective: To analyze 10.5 years' experience with hidradenoma papilliferum in Ferrara, Italy., Study Design: Review of 8 cases plus 25 from other area clinicians., Results and Conclusion: The clinical aspects of hidradenoma papilliferum are confusing. The tumor is uncommon, so physicians do not gain enough experience to recognize it. Histology is diagnostic and simple excision curative.
- Published
- 2000
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