296 results on '"ANNAKKAYA"'
Search Results
52. Is the Sleep Perception of Obstructive Sleep Apnea Patients Reliable?
- Author
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YILDIZ GÜLHAN, Pınar, primary, GÜLEÇ BALBAY, Ege, additional, and ANNAKKAYA, Ali Nihat, additional
- Published
- 2019
- Full Text
- View/download PDF
53. Obstrüktif Uyku Apnesi Hastalarının Uyku Algıları Güvenilir mi?
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YILDIZ GÜLHAN, Pınar, GÜLEÇ BALBAY, Ege, and ANNAKKAYA, Ali Nihat
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Perception,sleep apnea ,Medicine ,Algı,uyku apnesi ,psychological phenomena and processes ,nervous system diseases ,respiratory tract diseases ,Tıp - Abstract
Amaç: Bu çalışmanın amacı, hastaların polisomnografi (PSG) verileri ile PSG incelemesi sonrası sabah hastaların kendileri tarafından bildirilen verilerin birbiri ile uyumunu değerlendirmektir.Gereç ve Yöntemler: Çalışmaya Düzce Üniversitesi Tıp Fakültesi Göğüs Hastalıkları Uyku Polikliniği’ne başvurmuş ardışık 134 kişi dahil edildi. PSG ve uyku algısı ile ilgili sorular tüm katılımcılara aynı hekim tarafından yüz yüze görüşme ile uygulandı.Bulgular: Çalışmaya dahil edilen hastaların 90’ı (%67,2) erkek ve 44’ü (%32,8) kadın olup yaş ortalaması 47,3±12,6 yıl idi. Obstrüktif uyku apnesi (OUA) negatif olan hastalarda, hastaların sabah uyandıktan sonra kendileri tarafından bildirilen uyku süresi ile PSG cihazı ile ölçülen uyku süresi arasında anlamlı bir korelasyon varken (p=0,042; r=0,301), OUA (+) olan hastalarda hastaların sabah uyandıktan sonra kendileri tarafından bildirilen uyku süresi ile PSG cihazı ile ölçülen uyku süresi arasında korelasyon yoktu (p=0.269, r=0.125). Benzer şekilde, OUA (-) olan hastalarda hastaların sabah uyandıktan sonra kendileri tarafından bildirilen uyku latansı ile PSG cihazı ile ölçülen uyku latansı arasında anlamlı bir korelasyon varken (p=0.026, r=0.352), OUA (+) olan hastalarda hastaların sabah uyandıktan sonra kendileri tarafından bildirilen uyku latansı ile PSG cihazı ile ölçülen uyku latansı arasında korelasyon yoktu (p=0.060, r=0.223).Sonuç: OUA hastalarını değerlendirirken ve hastaların PSG sonrası ve öncesi tedavilerini açıklarken, hastaların algılarının bozulmuş olabileceği akılda tutulmalıdır. Bu nedenle, hasta ile görüşmelerde daha çok zaman ayırmak ve açıklamalarımızı daha açık ve anlaşılır bir şekilde yapmak gerektiğini düşünmekteyiz., Aim: The aim of this study, is to evaluate the consistency with the polysomnography (PSG) data of the patients and the data reported by the patients themselves after PSG examination in the morning.Material and Methods: One hundred and thirty-four consecutive individuals who were admitted to the Chest Disease Polyclinic for Sleep Disorders of Duzce University Medical Faculty were included in the study. PSG and the questions related to sleep perception was applied by the same physician with face to face interview to all participants.Results: Of the patients included in the study 90 (67.2%) were male and 44 (32.8%) were female, and the mean age was 47.3±12.6 years. While there was a significant correlation (p=0.042, r=0.301) between the sleep time reported by the patients themselves after waking up in the morning and the sleep time measured by the PSG in patients without obstructive sleep apnea (OSA), there was no correlation in OSA (+) patients (p=0.269, r=0.125). Similarly, while there was a significant correlation (p=0.026, r=0.352) between the sleep latency reported by the patients themselves after waking up in the morning and the sleep latency measured by the PSG in OSA (-) patients, there was no correlation in OSA (+) patients (p=0.060, r=0.223).Conclusion: While evaluating OSA patients and explaining their treatment before and after PSG, it should be kept in mind that they might have impaired perception. Therefore, we thought that we should spend more time to patients, and to make our explanations more clearly and understandably.
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- 2019
54. Should isoniazid prophylaxis be prescribed to the patients under tumor necrosis factor-alpha antagonists independent of tuberculin skin test?
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Leyla Yilmaz Aydin, Oner Balbay, Fatih Alasan, Ege Güleç Balbay, Şengül Cangür, and Ali Nihat Annakkaya
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Adult ,Male ,medicine.medical_specialty ,Tuberculosis ,030232 urology & nephrology ,Antitubercular Agents ,Tuberculin ,030209 endocrinology & metabolism ,Physical examination ,Anti TNF-alpha ,Etanercept ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Internal medicine ,medicine ,Isoniazid ,Humans ,Aged ,Ankylosing spondylitis ,Latent tuberculosis ,medicine.diagnostic_test ,business.industry ,Tuberculin Test ,Tumor Necrosis Factor-alpha ,Middle Aged ,medicine.disease ,bacterial infections and mycoses ,Infliximab ,Surgery ,tuberculosis ,Rheumatoid arthritis ,Chemoprophylaxis ,Female ,Tumor Necrosis Factor Inhibitors ,Geriatrics and Gerontology ,business ,medicine.drug - Abstract
Alasan, Fatih/0000-0003-0935-5927 WOS: 000490688100001 PubMed: 31615316 Introduction: The aim of this study was to present the follow-up results of 110 patients who were given anti-tumor necrosis factor alpha (TNF-?) therapy for rheumatic and dermatologic diseases in a country with a high rates of active and latent tuberculosis bacillus infection. Material and Methods: Between February 2008 and January 2015, 110 cases in the age range of 23?77 who are using anti-TNF-? were included in the study retro-prospectively. Results: 52.7% of them (n?=?58) were male. The most common diagnoses were rheumatoid arthritis (42.7%) and ankylosing spondylitis (38.2%). Most frequently given treatment were infliximab 37.3% and etanercept 30.9%, respectively. The 65 patients whose first tuberculin skin test (TST) value ?5?mm and above? was started daily 300?mg INH prophylaxis for 9?months but 3 patients had not been started because of refusing treatment. In only one case chemoprophylaxis has had to be interrupted because of high liver function test due to the INH prophylaxis. TST conversion was observed in 14 patients. Further follow-up, it was observed that 4 patients had TST's positivity. Isoniazide (INH) prophylaxis was started these 18 patients (42.9%). Although INH prophylaxis has been given in two patients, they developed active tuberculosis in follow-up. Conclusion: Considering the INH resistance in our country, all patients especially the ones with residual lesion and history of previous exposure, should be followed up closely during the anti-TNF-? treatment.
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- 2019
55. Akciğer Kanseri Tanısıyla Serviste Yatırılarak İzlenen Hastalarımızın Genel Özellikleri
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Pınar Yıldız Gülhan, Ali Nihat Annakkaya, Özlem Ataoğlu, and Ege Güleç Balbay
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lcsh:R5-920 ,pnömoni ,sigara ,Akciğer kanseri ,pneumonia ,cigarette ,Lung cancer ,lcsh:Medicine (General) - Abstract
Amaç: Bu çalışmanın amacı akciğer kanseri tanılı hastalarda; yatış nedenlerini, yatış sürelerini ve mortaliteyi etkileyen faktörleri incelemektirGereç ve Yöntemler: Hastanemiz göğüs hastalıkları kliniğine 2013-2018 tarihleri arasında akciğer kanseri tanısı ile başvurup yatışı yapılan 151 hasta geriye yönelik değerlendirildi. İnceleme sırasında hastaların patoloji raporları, ICD–10 tanı kodları, laboratuvar sonuçları ve anamnez arşivine kaydedilen bilgilerinden yararlanıldı.Bulgular: Vakaların %90,1’i erkek (n=136), %9,9’u (n=15) kadındı. Yaş ortalaması 65±10 (minimum: 45, maksimum: 86 yıl) idi. En sık tanı Küçük Hücre Dışı Akciğer Kanseri (KHDAK) idi (%84). Hastalarda görülen en sık semptom nefes darlığı (%77,5), en sık yatış nedeni pnömoni idi (%54,3). Sigara öyküsü sorgulandığında; hastaların %44,2’si halen sigara içmeye devam ediyordu. Taburculuk durumu değerlendirildiğinde gruplar arasında hücre tanısı (p=0,008) açısından anlamlı istatistiksel fark vardı. Yatış süreleri göz önünde bulundurulduğunda gruplar arasında; diyabet bulunan hastalarda yatış süresi anlamlı olarak kısaydı (p=0,023). Diğer komorbiditelerden KOAH ve kalp yetmezliği olanlarda yatış süresi uzun olsa da istatistiksel olarak anlamlılığa ulaşmadı (sırasıyla; p=0,455 p=0,519). Sonuç: Bu çalışmada akciğer kanseri tanısı almış hastaların yatış nedenlerini retrospektif olarak inceledik. Kanser hastalarının takibinde gelişebilecek pnömoni açısından koruyucu önlemler almak hastane yatış ve hasta maliyetlerini, morbidite ve mortaliyeyi azaltabilir. Sigara konusunda verilecek eğitim ve tedaviler hastalığın prognozunda önem arz etmektedir.
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- 2019
56. Assessment of the frequency of deep venous thromboembolism in obstructive sleep apnea syndrome
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Fuat Aytekin, Mehtap Oktay, Ali Nihat Annakkaya, Yagmur Bahar, Cigdem Sen, and Oner Balbay
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medicine.medical_specialty ,030232 urology & nephrology ,obstructive sleep apnea syndrome ,030209 endocrinology & metabolism ,macromolecular substances ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,D-dimer ,medicine ,Humans ,cardiovascular diseases ,Significant risk ,Patient group ,obstructive sleep apnea ,deep venous thrombosis ,Sleep Apnea, Obstructive ,business.industry ,Sleep apnea ,Venous Thromboembolism ,medicine.disease ,Confidence interval ,respiratory tract diseases ,Obstructive sleep apnea ,Venous thrombosis ,Lower Extremity ,Female ,Geriatrics and Gerontology ,business ,Venous thromboembolism - Abstract
WOS: 000482895400001 PubMed: 31437086 The present study aimed to investigate the frequency of deep venous thrombosis (DVT) among patients with obstructive sleep apnea syndrome (OSAS). Patients who referred the preliminary diagnosis of OSAS were included in this study. D-dimer levels of all patients were measured, and D-dimer (+) patients were evaluated by Doppler USG of the lower-extremity. Mean age of the patient group was 52 +/- 12 years and 31.8% (76/239) were women. The rate of D-dimer positivity among severe-OSAS cases (15/85) was significantly higher compared to the rest (13/154) (17.6% and 8.4%, respectively; p = 0.034). The risk of D-dimer positivity was elevated by 2.3 folds in severe-OSAS cases (OR: 2,324, 95% confidence interval: 1.048-5.152). Among 28 D-dimer (+) cases, 4 (14.2%) had DVT as demonstrated by USI of the lower-extremity. All four cases with DVT had severe OSAS. D-dimer was positive in 17.6% (15/85) of all severe OSAS cases. DVT was diagnosed in 4.7% (4/85) of severe-OSAS cases. DVT frequency was 26.6% (4/15) in D-dimer (+) severe-OSAS. Findings of this study indicate that severe-OSAS can be a significant risk factor for DVT. Additionally, data obtained in this study underline the benefits of questioning severe-OSAS patients with respect to DVT symptoms, investigating D-dimer levels and evaluating D-dimer (+) severe-OSAS cases for DVT prophylaxis.
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- 2019
57. Akciğer Kanseri Tanısıyla Serviste Yatırılarak İzlenen Hastalarımızın Genel Özellikleri
- Author
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YILDIZ GÜLHAN, Pınar, ATAOĞLU, Özlem, GÜLEÇ BALBAY, Ege, and ANNAKKAYA, Ali Nihat
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Health Care Sciences and Services ,Sağlık Bilimleri ve Hizmetleri ,Akciğer kanseri,pnömoni,sigara ,Lung cancer,pneumonia,cigarette - Abstract
Aim: The aim of thisstudy was to investigate the factors that determine hospitalization reasons,duration of hospitalization and the mortality of lung cancer patients. Material andMethod:151 patients who were admitted to the chest diseases clinic of our hospitalwith lung cancer diagnosis between 2013-2018 were evaluated retrospectively.The pathology reports, ICD-10 diagnostic codes, laboratory results andanamnesis archive were used in examination. Results: 90.1% of caseswere male (n=136) and 9.9% (n=15) were female. The mean age was 65±10 (minimum:45 years, maximum: 86 years). The most common diagnosis was Non Small Cell LungCancer (NSCLC) (84%). The most common symptom was dyspnea, (77.5%) most commonreason for hospitalization was pneumonia (54.3%). When smoking history wasquestioned, 44.2% of the patients were still smoking. Considering the situationof hospital discharge, there was a statistically significant difference betweengroups in terms of cell diagnosis (p=0.008). Considering of hospitalizationduration; It was significantly shorter in diabetes patients (p=0.023). Amongthe other comorbidities, although the duration of hospitalization was long, butit did not reach statistical significance in COPD and heart failure patients(p=0.455 p=0.519, respectively).Conclusion: In this study,we reviewed the causes of hospitalization in lung cancer patientsretrospectively. Taking preventive measures interms of pneumonia that may occur in the follow-up of cancer patients mayreduce hospitalization and patient costs, morbidity and mortality. Training andtreatments that given for smoking cessation are important in the prognosis ofthe disease., Amaç: Bu çalışmanınamacı akciğer kanseri tanılı hastalarda; yatış nedenlerini, yatış sürelerini vemortaliteyi etkileyen faktörleri incelemektirGereç veYöntemler:Hastanemiz göğüs hastalıkları kliniğine 2013-2018 tarihleri arasında akciğerkanseri tanısı ile başvurup yatışı yapılan 151 hasta geriye yönelikdeğerlendirildi. İnceleme sırasında hastaların patoloji raporları, ICD–10 tanıkodları, laboratuvar sonuçları ve anamnez arşivine kaydedilen bilgilerindenyararlanıldı.Bulgular: Vakaların%90,1’i erkek (n=136), %9,9’u (n=15) kadındı. Yaş ortalaması 65±10 (minimum:45, maksimum: 86 yıl) idi. En sık tanı Küçük Hücre Dışı Akciğer Kanseri (KHDAK)idi (%84). Hastalarda görülen en sık semptom nefes darlığı (%77,5), en sıkyatış nedeni pnömoni idi (%54,3). Sigara öyküsü sorgulandığında; hastaların%44,2’si halen sigara içmeye devam ediyordu. Taburculuk durumudeğerlendirildiğinde gruplar arasında hücre tanısı (p=0,008) açısından anlamlıistatistiksel fark vardı. Yatış süreleri göz önünde bulundurulduğunda gruplararasında; diyabet bulunan hastalarda yatış süresi anlamlı olarak kısaydı(p=0,023). Diğer komorbiditelerden KOAH ve kalp yetmezliği olanlarda yatışsüresi uzun olsa da istatistiksel olarak anlamlılığa ulaşmadı (sırasıyla;p=0,455 p=0,519).Sonuç: Buçalışmada akciğer kanseri tanısı almış hastaların yatış nedenleriniretrospektif olarak inceledik. Kanser hastalarının takibinde gelişebilecekpnömoni açısından koruyucu önlemler almak hastane yatış ve hasta maliyetlerini,morbidite ve mortaliyeyi azaltabilir. Sigara konusunda verilecek eğitim vetedaviler hastalığın prognozunda önem arz etmektedir.
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- 2019
58. Multidrug resistance-1 gene C3435T single nucleotide polymorphism in OSAS patients
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Ayada, Ceylan, Erbay, Ümran Toru, and Annakkaya, Ali Nihat
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Obstructive Sleep Apnea Syndrome (OSAS) ,C3435T Single Nucleotide Polymorphism ,Multi-Drug Resistant-1 (MDR-1) Gene ,Turkish Population ,respiratory tract diseases - Abstract
WOS: 000512905300018 Aim: Obstructive sleep apnea syndrome (OSAS) is characterized by decreased airflow (hypopnea) or complete interruption (apnea) and is characterized by airway narrowing, decreased oxyhemoglobin saturation, hypercapnia, and hyperventilation associated therewith. It is known that genetic factors play role in the pathogenesis of OSAS. Multi-drug resistant-1 (MDR-1) gene products have a role in the pathogenesis of several diseases related to oxidative stress. We aimed to evaluate the frequency of MDR-1 gene C/T polymorphism in patients with OSAS. Material and Method: This study was performed on 43 OSAS and 23 healthy individuals. Blood samples from each individual were collected in tubes with ethylenediaminetetraacetic add (EDTA). DNA was extracted from the blood samples. The MDR-1 gene polymorphism was detected by polymerase chain reaction (PCR) and enzyme digestion techniques. Results: The frequencies of MDR-1 genotypes were found 27.9% for CC, 41.9% for CT and 30.2% for TT in the OSAS group and 17.4% for CC, 65.2% for CT and 17.4% for TT in the control group. The distribution of MDR-1 gene C alleles was found to be 48.8% in COPD group and 50.0% in the control group; T alleles were found to be 51.2% in OSAS group and 50.0% in the control group. There was no statistically significant difference observed between the groups for genotype and allele frequency of MDR-1 gene (p>0.05). Discussion: We believe these results can be useful for large-scale population genetic research considering the frequency of the MDR-1 gene variation in OSAS patients in the Turkish population.
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- 2019
59. THE EFFECT OF NATURAL GAS WARMING ON EMERGENCY APPLICATIONS DUE TO RESPIRATORY TRACT DISEASES IN CHILDREN IN DUZCE CITY
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Gülhan, Pınar Yıldız, Balbay, Ege Güleç, Annakkaya, Ali Nihat, Balbay, Öner Abidin, and Arbak, Peri Meram
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natural gas ,PM10 ,clean fuel ,Child - Abstract
WOS: 000480511400054 The use of natural gas for heating purposes causes less air pollution than solid fuels. Preventing air pollution decreases hospital admissions due to respiratory infections in children. The aim of the study is to examine the impact of using more clean fuel for heating purpose on hospital admissions with respiratory tract diseases in children. The records of 126.940 pediatric patients who were admitted to Duzce University Medical Faculty Pediatric Emergency Medicine outpatient clinic between 2014 and 2017 were reviewed. The records of children diagnosed with respiratory diseases (n: 46137) were examined. During the same period, air monitoring measurements of the national air quality network were recorded. Of the children, 55.5% were male and 45.5% were female. Most of the children were among the age group of 2-5 years (44%). Between 2014 and 2017, the mean PM10 was observed to decrease (2014: 114.4, 2017:79, p < 0.0001), rate of natural gas usage (2014:52.9%, 2017: 64.2%, p
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- 2019
60. Is the sleep perception of obstructive sleep apnea patients reliable? [Obstrüktif uyku apnesi hastalarının uyku algıları güvenilir mi?]
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Gülhan, Pınar Yıldız, Balbay, Ege Güleç, and Annakkaya, Ali Nihat
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Perception ,Sleep apnea ,psychological phenomena and processes ,nervous system diseases ,respiratory tract diseases - Abstract
Aim: The aim of this study, is to evaluate the consistency with the polysomnography (PSG) data of the patients and the data reported by the patients themselves after PSG examination in the morning. Material and Methods: One hundred and thirty-four consecutive individuals who were admitted to the Chest Disease Polyclinic for Sleep Disorders of Duzce University Medical Faculty were included in the study. PSG and the questions related to sleep perception was applied by the same physician with face to face interview to all participants. Results: Of the patients included in the study 90 (67.2%) were male and 44 (32.8%) were female, and the mean age was 47.3±12.6 years. While there was a significant correlation (p=0.042, r=0.301) between the sleep time reported by the patients themselves after waking up in the morning and the sleep time measured by the PSG in patients without obstructive sleep apnea (OSA), there was no correlation in OSA (+) patients (p=0.269, r=0.125). Similarly, while there was a significant correlation (p=0.026, r=0.352) between the sleep latency reported by the patients themselves after waking up in the morning and the sleep latency measured by the PSG in OSA (-) patients, there was no correlation in OSA (+) patients (p=0.060, r=0.223). Conclusion: While evaluating OSA patients and explaining their treatment before and after PSG, it should be kept in mind that they might have impaired perception. Therefore, we thought that we should spend more time to patients, and to make our explanations more clearly and understandably. © 2019, Duzce University Medical School. All rights reserved.
- Published
- 2019
61. EFFECT OF SYMPTOM-TO-TREATMENT INTERVAL ON PROGNOSIS IN LUNG CANCER
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Annakkaya, Ali Nihat, Arbak, Peri, Balbay, Oner, Bilgin, Cahit, Erbas, Mete, and Bulut, Ismet
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- 2007
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62. Intima-Media Thickness of the Common Carotid Artery in Highway Toll Collectors
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Erdogmus, Besir, Yazici, Burhan, Annakkaya, Ali Nihat, Bilgin, Cahit, Safak, Alp Alper, Arbak, Peri, and Tugay, Ali
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- 2006
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63. Association between Varicocele and Chronic Obstructive Pulmonary Disease
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Erdogmus, Besir, Yazici, Burhan, Balbay, Oner, Annakkaya, Ali Nihat, Ozdere, Betul Ayca, and Bulut, Ismet
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- 2006
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64. Persistent serpentine supravenous hyperpigmented eruption associated with docetaxel
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Aydogan, I, Kavak, A, Parlak, A H, Alper, M, Annakkaya, A N, and Erbas, M
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- 2005
65. What should be the appropriate minimal duration for patient examination and evaluation in pulmonary outpatient clinics?
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Musellim, Benan, Borekci, Sermin, Uzan, Gulfidan, Sak, Zafer Hasan Ali, Ozdemir, Secil Kepil, Altinisik, Goksel, Altunbey, Sinem Agca, Sen, Nazan, Kilinc, Oguz, Yorgancioglu, Arzu, Yilmaz, Nafiye, Ulasli, Sevinc Sarinc, Salepci, Banu, Ocakli, Birsen, Sokullu, Zinet Gul Ersoy, Uzun, Oguz, Kurtulus, Serif, Uslu, Selen, Saritas, Emel, Genc, Sebahat, Annakkaya, Ali Nihat, Aydin, Omur, Bilgin, Cahit, Turk, Murat, Ozmen, Ipek, Tasbakan, Mehmet Sezai, Halis, Ayse Nigar, Bahcecioglu, Sakine Nazik, Dabak, Gul, Isik, Sacide Rana, Ozturk, Ayse Bilge, Akgun, Metin, Pihtili, Aylin, Ozkan, Gulcihan, Balbay, Ege Gulec, Okumus, Gulfer, Onen, Zeynep Pinar, Yasayancan, Nursen, Uysal, Funda Elmas, Hanta, Ismail, Kaya, Zuleyha, Turker, Hatice, Berkesoglu, Cigdem, Celik, Pinar, Cetinkaya, Pelin Duru, Gundogus, Baran, Ongen, Gul, Tuncay, Esin, Erboy, Fatma, Zonguldak Bülent Ecevit Üniversitesi, Istanbul University, Cerrahpasa Medical Faculty, Department of Chest Diseases, Istanbul, Turkey, Haseki Training and Research Hospital, Istanbul, Turkey, Harran University Medical Faculty, Department of Chest Diseases, Sanli Urfa, Turkey, Ankara Diskapi Yildirim Beyazit Training and Research Hospital, Allergy and Immunology Clinic, Ankara, Turkey, Pamukkale University Medical Faculty, Department of Chest Diseases, Denizli, Turkey, Health Sciences University, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey, Baskent University, Adana Dr. Turgut Noyan, Teaching and Medical Research Center, Adana, Turkey, Dokuz Eylul University Medical Faculty, Department of Chest Diseases, Izmir, Turkey, Celal Bayar University Medical Faculty, Department of Chest Diseases, Manisa, Turkey, Çukurova Üniversitesi, Ege Üniversitesi, Musellim, B, Borekci, S, Uzan, G, Sak, ZHA, Ozdemir, SK, Altinisik, G, Altunbey, SA, Sen, N, Kilinc, O, Yorgancioglu, A, Yilmaz, N, Ulasli, SS, Salepci, B, Ocakli, B, Sokullu, ZGE, Uzun, O, Kurtulus, S, Uslu, S, Saritas, E, Genc, S, Annakkaya, AN, Aydin, O, Bilgin, C, Turk, M, Ozmen, I, Tasbakan, MS, Halis, AN, Bahcecioglu, SN, Dabak, G, Isik, SR, Ozturk, AB, Akgun, M, Pihtili, A, Ozkan, G, Balbay, EG, Okumus, G, Onen, ZP, Yasayancan, N, Uysal, FE, Hanta, I, Kaya, Z, Turker, H, Berkesoglu, C, Celik, P, Cetinkaya, PD, Gundogus, B, Ongen, G, Tuncay, E, Erboy, F, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Bilgin, Cahit, and OMÜ
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lcsh:Diseases of the circulatory (Cardiovascular) system ,lung disease ,Outpatient clinics ,patient examination ,suggested duration ,patient monitoring ,Respiratory System ,01 natural sciences ,0302 clinical medicine ,Outpatient clinic ,030212 general & internal medicine ,Duration (project management) ,hospital ,outpatient care ,time ,adult ,University hospital ,Inappropriate Prescriptions ,medical history ,aged ,patient assessment ,female ,Original Article ,Cardiology and Cardiovascular Medicine ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,chronic lung disease ,Article ,03 medical and health sciences ,Patient satisfaction ,male ,medicine ,consultation ,In patient ,human ,0101 mathematics ,Preventive healthcare ,lcsh:RC705-779 ,business.industry ,010102 general mathematics ,outpatient department ,lcsh:Diseases of the respiratory system ,major clinical study ,lcsh:RC666-701 ,Physical therapy ,Patient examination ,Surgery ,business ,scientist - Abstract
WOS: 000405969500005, PubMed ID: 28808489, INTRODUCTION: Patient examinations performed in a limited time period may lead to impairment in patient and physician relationship, defective and erroneous diagnosis, inappropriate prescriptions, less common use of preventive medicine practices, poor patient satisfaction, and increased violent acts against health-care staff. OBJECTIVE: This study aimed to determine the appropriate minimal duration of patient examination in the pulmonary practice. METHODS: A total of 49 researchers from ten different study groups of the Turkish Thoracic Society participated in the study. The researchers were asked to examine patients in an almost ideal manner, without time constraint under available conditions. RESULTS: A total of 1680 patient examinations were reviewed. The mean duration of patient examination in ideal conditions was determined to be 20.4 +/- 9.6 min. Among all steps of patient examination, the longest time was spent for "taking medical history." The total time spent for patient examination was statistically significantly longer in the university hospitals than in the governmental hospitals and training and research hospitals (P < 0.001). Among different patient categories, the patients with a chronic disorder presenting for the first time and were referred from primary or secondary to tertiary care for further evaluation have required the longest time for patient examination. CONCLUSION: According to our study, the appropriate minimal duration for patient examination is 20 min. It has been observed that in university hospitals and in patients with chronic pulmonary diseases, this duration has been increased to above 25 min. The durations in clinical practice should be planned accordingly.
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- 2017
66. Annual Changes in Forced Expiratory Flows in Toll Collectors: Results from a Four Years Observation
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Cahit Bilgin, Sefa Levent Özşahin, Peri Arbak, Ali Nihat Annakkaya, Oner Balbay, Arbak, P, Balbay, O, Annakkaya, AN, Bilgin, C, Ozsahin, SL, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Bilgin, Cahit, [Arbak, Peri -- Balbay, Oener -- Annakkaya, Ali Nihat] Duzce Univ, Dept Chest Dis, Fac Med, TR-81620 Konuralp, Duzce, Turkey -- [Bilgin, Cahit] Hendek Govt Hosp, Dept Chest Dis, Hendek, Sakarya, Turkey -- [Ozsahin, Sefa Levent] Cumhuriyet Univ, Dept Chest Dis, Fac Med, Sivas, Turkey, Annakkaya, Ali Nihat N -- 0000-0002-7661-8830, and BILGIN, CAHIT -- 0000-0003-2213-5881
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Adult ,Male ,Chronic bronchitis ,Turkey ,Exacerbation ,Health, Toxicology and Mutagenesis ,Annual changes ,FEV1/FVC ratio ,Occupational Exposure ,Surveys and Questionnaires ,Humans ,Medicine ,Longitudinal Studies ,Respiratory sounds ,Forced expiratory flows ,Toll collectors ,Pleurisy ,Tuberculosis, Pulmonary ,Respiratory Sounds ,Vehicle Emissions ,Asthma ,Polycyclic Sesquiterpenes ,biology ,medicine.diagnostic_test ,Terpenes ,business.industry ,Incidence ,Incidence (epidemiology) ,Smoking ,Public Health, Environmental and Occupational Health ,Forced Expiratory Flow Rates ,respiratory system ,medicine.disease ,Respiratory Function Tests ,respiratory tract diseases ,Dyspnea ,Cough ,Spirometry ,Population Surveillance ,Toll ,Epidemiological Monitoring ,biology.protein ,Female ,business ,Environmental Monitoring ,Demography - Abstract
WOS: 000264777200009, PubMed ID: 19367045, Diesel exhaust (DE) has been accused for various health outcomes including exacerbation of asthma, chronic bronchitis. Exposure to DE has long-term effects on lung development in children and reductions in lung function have been reported. The aim of the study was to evaluate the annual changes in forced expiratory flows among toll collectors in Duzce city from 2002 to 2005. Annual FVC, FEV1 and MMF changes in smoker and nonsmoker 58 toll collectors and 37 controls selected among men who worked in the same company as officer have been followed up. No significant changes were seen in expiratory flows among smoker-nonsmoker toll collectors and controls (p>0.05). Annual FVC, FEV1 and MMF changes were not significantly different between smoker and nonsmoker toll collectors. Twelve toll collectors (20.7%) in the study group and 4 (10.8%) controls were found to have FEV1 and FVC below longitudinal lower limit of normal. The difference between groups did not reach statistically significance (p>0.05). Toll collectors (18/58) and controls (15/37) with spirometric measurements for three times showed no difference according to the rate of annual difference in either FEV1 (-21.3 +/- 133.1 ml/yr vs -44.3 +/- 166.6 (ml/yr) or FVC (13.2 +/- 202.9 ml/yr vs. -16.1 +/- 204.2 ml/yr). Further investigations including large groups with long term follow up are needed to observe annual FVC, FEV1 and MMF changes among toll collectors.
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- 2009
67. Hiperkapnik Solunum Yetmezliği Gelişen Kronik Obstrüktif Akciğer Hastalığı Hastalarında Noninvaziv AVAPS (Average Volume Assured Pressure Support) Modu
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Fuat Aytekin, Ege Güleç Balbay, Peri Arbak, Ali Nihat Annakkaya, and Oner Balbay
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KOAH,Solunum yetmezliği ,Respiratory Failure ,Health Care Sciences and Services ,business.industry ,Medicine ,COPD ,General Medicine ,Sağlık Bilimleri ve Hizmetleri ,Nuclear medicine ,business ,AVAPS - Abstract
Amaç: Bu çalışmada, AVAPS (Average Volume Assured Pressure Support) modu ile Noninvazif Mekanik Ventilasyon (NMV) uygulanan hastalarda hasta uyumu ve klinik başarıoranlarının araştırılması amaçlanmıştır. Bu çalışma Düzce Üniversitesi Bilimsel AraştırmaProjesidir (Proje No: 2015.04.03.312).Yöntem:Hiperkapnik Solunum YetmezliğiGelişen 22 Kronik Obstrüktif Akciğer Hastalığı (KOAH) hastalarına AVAPS modu uygulandı.Başlangıç parametreleri olarak; AVAPS ModundaIPAP Max 20 cmH2O, IPAP Min 12 cmH2O, Hedef Tidal volüm= İdealkilo x 6 ml/kg, EPAP 5 cmH2O ayarları ile başlanıp hastanın tolere ettiği ölçüde arttırılacakve SaO2 ≥ %90 olacak şekilde verildi. Hastaya verilen basınçdesteğinin 6 ml/kg TV’ü oluşturacak şekilde olmasına dikkat edildi. Hastaların NIVbağlandıktan sonra 1, 2, 8 ve 24. saatlerdearter kan gazı kontrolleri, nabız, solunum sayısı, Borg dispne skalasıölçümleri yapıldı.Bulgular:Çalışmaya dahil edilen yaş ortalaması 70±10 olan 22 hastanın %72,7 (n:16)’sierkekti. Geliş APACHE Skor ortalaması 16,50±4,24’tü. Geliş nabız ve solunumsayısı ortamaları sırasıyla 96±13 ve24±4 idi. Borg dispne skalasıortancası 6 (min:2, max:8) idi. Hastaların %59 (n:13)’unda 24saat içerisinde PH değerleri normal aralığına ulaştı. Hastaların NMV öncesi PH, PCO2, PaO2/FiO2ve Borg dispne skalası değerler ile NMV uygulamasının 1, 2, 8, 24 saat PH, PCO2,PaO2/FiO2 ve Borg dispne skalası değerlerikarşılaştırıldığında istatistiksel anlamlı olarak PH (p, Objective: In this study, weaimed to investigate patient compliance and clinical success rates in patientsundergoing NIV with AVAPS (Average Volume Assured Pressure Support) mode. Thisstudy is Düzce University Scientific Research Project (Project No: 2015.04.03.312).Method: As initialparameters; IPAP Max 20 cm H2O, IPAP Min 12 cm H2O, Target Tidal volume = Idealweight 6 ml / kg EPAP in AVAPS mode, starting with 5 cm H2O settings andincreasing to the extent that the patient is tossed and SaO2 ≥ 90% . Care was takento ensure that the pressure support supplied to the patient was 6 ml / kg TV.Arterial blood gas controls, pulse rate, respiratory rate and Borg dyspnea weremeasured at 1, 2, 8 and 24 hours after NMV adherence of the patients.Results: 72.7% (n: 16) of 22patients included in the study had a mean age of 70 ± 10. The arrival APACHEScore averaged 16,50 ± 4,24. The number of arriving pulses and respiration were96 ± 13 and 24 ± 4, respectively. Borg dyspnea scale mean was 6 (min: 2, max:8). 59% (n: 13) of the patients had undetectable pH values within 24 hours.When PH, PCO2, PaO2 / FiO2 and Borg dyspnea scores of patients before NIV and NIVapplication values of 1,2,8,24 hours PH, PCO2, PaO2 / FiO2 and Borg dyspneascores of patients were compared statistically, PH (p
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- 2018
68. Waterpipe (narghile, hookah) tobacco smoking-induced acute eosinophilic pneumonia
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Oner Balbay, Fuat Aytekin, Binnur Onal, Ege Gulec Balbay, Ali Nihat Annakkaya, and Özlem Öztürk
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lcsh:Internal medicine ,medicine.medical_specialty ,Acute eosinophilic pneumonia ,medicine.diagnostic_test ,business.industry ,government.form_of_government ,Hookah Tobacco ,cigarette ,respiratory system ,tobacco ,Hypoxemia ,respiratory tract diseases ,Bronchoalveolar lavage ,Erythrocyte sedimentation rate ,Internal medicine ,government ,medicine ,Eosinophilia ,Arterial blood ,narghile ,medicine.symptom ,lcsh:RC31-1245 ,business ,Pulmonary Eosinophilia - Abstract
Annakkaya, Ali Nihat N/0000-0002-7661-8830 WOS: 000431767800010 Acute eosinophilic pneumonia (AEP) is characterized by a febrile illness, diffuse pulmonary infiltrates, hypoxemic respiratory failure, and pulmonary eosinophilia. A temporal relationship has been described in a number of patients between the development of AEP and the recent onset of cigarette smoking. A 22-year-old male patient with no known chronic disease was admitted to the emergency service for 3 days with the complaints of cough, fever, dyspnea, and pleuritic chest pain. He was formerly a nonsmoker but was a waterpipe (narghile, hookah) tobacco smoker as a new habit once a night for the last 2 months. The erythrocyte sedimentation rate and C-reactive protein are elevated. Arterial blood gases revealed moderate hypoxemia. Computed tomography scans included bilateral, random, and patchy ground-glass opacities and also small bilateral pleural effusions. Echocardiograhic examination was normal. We had accepted the patient as an acute eosinophilic pneumonia due to rapid response to corticosteroid treatment, no microorganism in bronchoalveolar lavage (BAL) culture, and predominant eosinophilia was observed (70%-80%) in BAL.
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- 2018
69. Should isoniazid prophylaxis be prescribed to the patients under tumor necrosis factor-alpha antagonists independent of tuberculin skin test?
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Alaşan, Fatih, primary, Güleç Balbay, Ege, additional, Cangür, Şengül, additional, Balbay, Öner, additional, Yılmaz Aydın, Leyla, additional, and Annakkaya, Ali Nihat, additional
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- 2019
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70. Akciğer Kanseri Tanısıyla Serviste Yatırılarak İzlenen Hastalarımızın Genel Özellikleri
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Yıldız Gülhan, Pınar, primary, Ataoğlu, Özlem, additional, Güleç Balbay, Ege, additional, and ANNAKKAYA, Ali Nihat, additional
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- 2019
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71. Assessment of the frequency of deep venous thromboembolism in obstructive sleep apnea syndrome
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Bahar, Yagmur, primary, Annakkaya, Ali Nihat, additional, Sen, Cigdem, additional, Oktay, Mehtap, additional, Aytekin, Fuat, additional, and Balbay, Oner, additional
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- 2019
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72. The Evaluation of Family Physicians’ Knowledge on the Use of Inhalation Devices
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Ali Nihat Annakkaya, Hasan Süner, Elif Tanriverdi, Kezban Özmen Süner, and Sinem Iliaz
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medicine.medical_specialty ,lcsh:Internal medicine ,inhalation administration ,business.industry ,Inhalation Devices ,primary care physicians ,medicine.disease ,Asthma ,Medicine ,COPD ,Medical emergency ,business ,Intensive care medicine ,lcsh:RC31-1245 - Abstract
Annakkaya, Ali Nihat N/0000-0002-7661-8830 WOS: 000361630600006 Objective: Nowadays, inhalation techniques have an important role in treatment of asthma and chronic obstructive pulmonary disease (COPD). Correct application of inhalation devices is important for optimal therapeutic efficacy. Showing inhalation techniques to patients receiving inhaler therapy in more than one visit reduce the device usage errors. It is important to observe the deficiencies and errors of the patients in the primary health care where the patients frequently admitted. In our study we aimed to evaluate the knowledge of family physians on inhaler device usage in their clinical practice. Methods: Family physicians who work in primary health care services were visited face to face. Fifty family physicians who were in the institution at visit day and agreed to participate in the study were included in the study. The questionnaire consisting of 15 questions were asked each family physician. Then, seven different inhalation devices were evaluated with 10 step scoring system of inhaler device usage. Results: Twenty eight (56%) physicians were female and 22 (44%) were male. The mean age was 36.3 +/- 6.7 years and mean working time as a family physician was 5.12 +/- 2.8 years. Nineteen physicians participated to a meeting about usage of inhaler devices in the past. Average scores for inhaler devices were found 7.96 +/- 2.91 for metered-dose inhaler, 7.54 +/- 3.93 for discus, 7.28 +/- 4.04 for handihaler, 6.38 +/- 4.4 for aerolizer, 6.12 +/- 4.22 for turbuhaler, 5.98 +/- 4 for easyhaler and 5.72 +/- 4.59 for sanohaler, respectively. There was no relation between the inhaler devices usage scores and sex, age, duration of being family physician (p>0.05). The average scores of physicians who participated to a training were better than the physicians who didn't participate for metered-dose inhalers, turbuhaler, aerolizer and handihaler (p=0.049, p=0.05, p=0.013 and p=0.021, respectively). Conclusion: We thought that training of family physicians for inhaler devices is necessary to improve patients' compliance and successful treatment.
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- 2015
73. Evaluation of Patients with Fibrotic Interstitial Lung Disease: Preliminary results from the Turk-UIP Study.
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Benan, Musellim, Nesrin, Mogulkoc, Oguz, Uzun, Fatma, Tokgoz Akyil, Haluk, Turktas, Ozlem, Ozdemir Kumbasar, Gulfer, Okumus, Candan, Ogus, Hulya, Dirol, Adil, Zamani, Tulin, Sevim, Nihat, Annakkaya Ali, Akinci, Ozyurek Berna, Ismail, Hanta, Yusuf, Aydemir, Ebru, Cakir Edis, Bahar, Kurt, Can, Tertemiz Kemal, Levent, Tabak, and Onur, Yazici
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CLINICAL pathology ,IDIOPATHIC pulmonary fibrosis ,CHEST X rays ,BIOPSY ,INTERSTITIAL lung diseases ,DIFFERENTIAL diagnosis ,SEX distribution ,SYMPTOMS ,BLOOD sedimentation ,COMPUTED tomography ,SMOKING - Abstract
OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERS/JRS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8±9.0 years) were evaluated. Of the patients with sufficient data for diagnosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPF. None of the women <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPF. Presence of at least 1 of the symptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantly higher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively). CONCLUSION: The rate of IPF among patients with fibrotic ILD was 50%. In the differential diagnosis of IPF, sex, smoking habits, and the presence of clubbing are important. The presence of symptoms related to CTD, ESR elevation, and FANA positivity reduce the likelihood of IPF. [ABSTRACT FROM AUTHOR]
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- 2021
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74. Are serum eosinophilic cationic protein levels of toll collectors affected by diesel exhaust exposure?
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Ali Nihat Annakkaya, Özlem Yavuz, Oner Balbay, Cahit Bilgin, Ege Gulec Balbay, Peri Arbak, Bilgin, C, Arbak, P, Yavuz, O, Balbay, EG, Balbay, O, Annakkaya, AN, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Bilgin, Cahit, and Tıp Fakültesi
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Diesel exhaust ,Pulmonary function ,0206 medical engineering ,02 engineering and technology ,030204 cardiovascular system & hematology ,complex mixtures ,Pulmonary function testing ,03 medical and health sciences ,0302 clinical medicine ,Animal science ,General & Internal Medicine ,Medicine ,Respiratory system ,Toll collectors ,Eosinophil cationic protein ,biology ,business.industry ,PEF variability ,Significant difference ,General Medicine ,respiratory system ,020601 biomedical engineering ,ECP ,Diesel Exhaust Particulate ,respiratory tract diseases ,Toll ,Immunology ,biology.protein ,Original Article ,Smoking status ,business - Abstract
Yavuz, Özlem (Balikesir Author), Objective: There are few studies on the diesel exhaust particulates (DEP) / eosinophilic cationic protein (ECP) level relationship. This study aimed to detect ECP levels in a highly DE exposed group, named as toll collectors. Methods: In a cross-sectional study, levels of serum ECP, rates of respiratory symptoms, mean levels of respiratory functions, smoking status, and variations in peak expiratory flow (PEF) during weekends and working days were compared for 68 toll collectors (TC) (range of age, 24-48 years) and 28 controls (range of age, 25-61 years). All subjects in the study group were men. Results: No significant difference was observed in terms of symptoms and smoking rates between the toll collectors and control group. The number of toll collectors [12/68 (17.7%) vs 1/28 (3.5%)] with diurnal PEF variability in the working period was higher than that of controls (p=0.058). Mean ECP level of toll collectors was higher than that of controls (32.8 vs 21.4 ng/L), but the difference was not significant. Mean ECP levels were higher in subjects experiencing diurnal PEF variability during work and off-work periods (34.9 vs 28.3 ng/L, p=0.410). Conclusions: Serial PEF measurements combined with serum ECP measurements did not add a new tool to detect the sensitivity of workers dealing with DE. Much more diesel exhaust exposed workers should be included to search for cheap and available methods when evaluating airway.
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- 2016
75. Assessment of the frequency of deep venous thromboembolism in obstructive sleep apnea syndrome.
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Bahar, Yagmur, Annakkaya, Ali Nihat, Sen, Cigdem, Oktay, Mehtap, Aytekin, Fuat, and Balbay, Oner
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- *
SLEEP apnea syndromes , *THROMBOEMBOLISM , *VENOUS thrombosis , *FIBRIN fragment D , *PULMONARY embolism - Abstract
The present study aimed to investigate the frequency of deep venous thrombosis (DVT) among patients with obstructive sleep apnea syndrome (OSAS). Patients who referred the preliminary diagnosis of OSAS were included in this study. D-dimer levels of all patients were measured, and D-dimer (+) patients were evaluated by Doppler USG of the lower-extremity. Mean age of the patient group was 52 ± 12 years and 31.8% (76/239) were women. The rate of D-dimer positivity among severe-OSAS cases (15/85) was significantly higher compared to the rest (13/154) (17.6% and 8.4%, respectively; p = 0.034). The risk of D-dimer positivity was elevated by 2.3 folds in severe-OSAS cases (OR: 2,324, 95% confidence interval: 1.048-5.152). Among 28 D-dimer (+) cases, 4 (14.2%) had DVT as demonstrated by USI of the lower-extremity. All four cases with DVT had severe OSAS. D-dimer was positive in 17.6% (15/85) of all severe OSAS cases. DVT was diagnosed in 4.7% (4/85) of severe-OSAS cases. DVT frequency was 26.6% (4/15) in D-dimer (+) severe-OSAS. Findings of this study indicate that severe-OSAS can be a significant risk factor for DVT. Additionally, data obtained in this study underline the benefits of questioning severe-OSAS patients with respect to DVT symptoms, investigating D-dimer levels and evaluating D-dimer (+) severe-OSAS cases for DVT prophylaxis. [ABSTRACT FROM AUTHOR]
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- 2020
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76. Should isoniazid prophylaxis be prescribed to the patients under tumor necrosis factor-alpha antagonists independent of tuberculin skin test?
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Alaşan, Fatih, Güleç Balbay, Ege, Cangür, Şengül, Balbay, Öner, Yılmaz Aydın, Leyla, and Annakkaya, Ali Nihat
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TUMOR necrosis factors ,TUBERCULIN test ,SKIN tests ,ISONIAZID ,RHEUMATOID arthritis diagnosis ,ANKYLOSING spondylitis - Abstract
Introduction: The aim of this study was to present the follow-up results of 110 patients who were given anti-tumor necrosis factor alpha (TNF-α) therapy for rheumatic and dermatologic diseases in a country with a high rates of active and latent tuberculosis bacillus infection.Material and Methods: Between February 2008 and January 2015, 110 cases in the age range of 23-77 who are using anti-TNF-α were included in the study retro-prospectively.Results: 52.7% of them (n = 58) were male. The most common diagnoses were rheumatoid arthritis (42.7%) and ankylosing spondylitis (38.2%). Most frequently given treatment were infliximab 37.3% and etanercept 30.9%, respectively. The 65 patients whose first tuberculin skin test (TST) value "5 mm and above" was started daily 300 mg INH prophylaxis for 9 months but 3 patients had not been started because of refusing treatment. In only one case chemoprophylaxis has had to be interrupted because of high liver function test due to the INH prophylaxis. TST conversion was observed in 14 patients. Further follow-up, it was observed that 4 patients had TST's positivity. Isoniazide (INH) prophylaxis was started these 18 patients (42.9%). Although INH prophylaxis has been given in two patients, they developed active tuberculosis in follow-up.Conclusion: Considering the INH resistance in our country, all patients especially the ones with residual lesion and history of previous exposure, should be followed up closely during the anti-TNF-α treatment. [ABSTRACT FROM AUTHOR]- Published
- 2020
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77. Pulmonary functions, respiratory complaints and radiographic findings in aluminium foundry workers
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Cahit Bilgin, Ege Gulec Balbay, Peri Arbak, Elif Nisa Unlu, Ali Nihat Annakkaya, Oner Balbay, and Mehmet Akdogan
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medicine.medical_specialty ,business.industry ,Pneumoconiosis ,Radiography ,chemistry.chemical_element ,Urine ,medicine.disease ,chemistry ,Aluminium ,Internal medicine ,Epidemiology ,medicine ,Respiratory system ,business ,Respiratory health ,Asthma - Abstract
Introduction: It has been well known that occupational exposure to aluminium leads to smelter asthma and pneumoconiosis. Epidemiological studies are needed to search the exposure conditions and duration. Scope: It is aimed to investigate the type of respiratory involvement. Materials and Methods: Male aluminium foundry workers living in Adapazari district (42 male, mean age: 32.2 ± 6.9 years) compared with 33 male controls without exposure (mean age: 30.0 ± 7.9 years). Mean urine aluminium levels of workers (10.7 ± 8.8 mcg/lt) were significantly higher than those of controls (2.2 ± 0.8, p Conclusion: Mean occupational aluminium exposure of 5 years leads a significant deterioration of workers respiratory health, pulmonary funcions and radiology. Preventive measures should be taken in aluminium foundry sector.
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- 2017
78. Türk Toraks Derneği Olağan İnterstisyel Pnömoni(UIP) Araştırması
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KALPAKLIOĞLU, AYŞE FÜSUN, UZEL, IŞIL, BAŞYİĞİT, İLKNUR, EKİCİ, AYNUR, KANMAZ, ZEHRA DİLEK, YILMAZEL UÇAR, ELİF, TUNCAY, ESİN, TOPÇU, AYŞE FÜSUN, ÇAMSARI, GÜNGÖR, YILDIRIM, ZEYNEP BİNNAZ, UZARSLAN, ESRA, BOZKUŞ, FULSEN, DALAR, LEVENT, HAZAR, ARMAĞAN, KURT, EMİNE BAHAR, ANNAKKAYA, ALİ NİHAT, OKUMUŞ, NİGAR GÜLFER, NİKSAROĞLU, ELİF YELDA, YILMAZ KARA, BİLGE, YAZICI, ONUR, GÜNGÖR, ATEŞ, ÖĞÜŞ, ALİYE CANDAN, ZAMANİ, ADİL, UZUN, OĞUZ, TOKGÖZ AKYIL, FATMA, ÖZYÜREK AKINCI, BERNA, AYDEMİR, YUSUF, TERTEMİZ, KEMAL CAN, HANTA, İSMAİL, TÜRKTAŞ, HALUK ŞABAN, ÖZSU, SAVAŞ, SALEPÇİ, BANU, ÇAKIR EDİS, EBRU, ÖZDEMİR KUMBASAR, ÖZLEM, TABAK, LEVENT, ERDOĞAN, YURDANUR, SEVİM, TÜLİN, DURU, SERAP, TÜRKER, HATİCE, MÜSELLİM, BENAN, and MOĞOLKOÇ, NESRİN
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- 2017
79. and evaluation in pulmonary outpatient clinics?
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Musellim, B, Borekci, S, Uzan, G, Sak, ZHA, Ozdemir, SK, Altinisik, G, Altunbey, SA, Sen, N, Kilinc, O, Yorgancioglu, A, Yilmaz, N, Ulasli, SS, Salepci, B, Ocakli, B, Sokullu, ZGE, Uzun, O, Kurtulus, S, Uslu, S, Saritas, E, Genc, S, Annakkaya, AN, Aydin, O, Bilgin, C, Turk, M, Ozmen, I, Tasbakan, MS, Halis, AN, Bahcecioglu, SN, Dabak, G, Isik, SR, Ozturk, AB, Akgun, M, Pihtili, A, Ozkan, G, Balbay, EG, Okumus, G, Onen, ZP, Yasayancan, N, Uysal, FE, Hanta, I, Kaya, Z, Turker, H, Berkesoglu, C, Celik, P, Cetinkaya, PD, Gundogus, B, Ongen, G, Tuncay, E, and Erboy, F
- Subjects
Outpatient clinics ,patient examination ,suggested duration - Abstract
INTRODUCTION: Patient examinations performed in a limited time period may lead to impairment in patient and physician relationship, defective and erroneous diagnosis, inappropriate prescriptions, less common use of preventive medicine practices, poor patient satisfaction, and increased violent acts against health-care staff.
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- 2017
80. Fatigue Frequency and Related Factors in Patients with Sarcoidosis
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Peri Erbak, Pınar Yıldız Gülhan, Merve Ercelik, Ali Nihat Annakkaya, and Ege Gulec Balbay
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Related factors ,medicine.medical_specialty ,business.industry ,Internal medicine ,Medicine ,In patient ,Sarcoidosis ,business ,medicine.disease - Published
- 2019
81. Clinical and Polysomnographic Evaluation of Sleep Breathing Disorders in Patients with Sarcoidosis
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Mehmet Fatih Elverisli, Pınar Yıldız Gülhan, Ozlem Ataoglu, Ali Nihat Annakkaya, and Peri Arbak
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Pediatrics ,medicine.medical_specialty ,business.industry ,medicine ,In patient ,Sarcoidosis ,business ,medicine.disease ,Sleep in non-human animals ,Breathing disorders - Published
- 2019
82. Pandemi Sürecinde Düzce Üniversitesi Hastanesi: Başhekimlik Yönünden.
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Akcan, Fatih Alper, Öneç, Kürşad, Annakkaya, Ali Nihat, Pehlivan, Mevlüt, Karaduman, Zekeriya Okan, Balbay, Öner Abidin, Çakar, Nigar Demircan, Eravcı, Fatma, Çelik, Muhammet, Kaplan, Zekeriya, Şen, Nevin, Ergün, Hacer Ak, Kuzyaka, İlknur, Bulut, Feryal, Yalçın, Bedri, Öner, Seçkin, Odabaşı, Nuray, Köklü, Şaban, Koku, Sercan, and Şengül, Kadriye
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ACADEMIC medical centers ,EMERGENCY management ,EMOTIONS - Abstract
Copyright of Konuralp Medical Journal / Konuralp Tip Dergisi is the property of Duzce University Medical School and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2020
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83. Noninvasive AVAPS (Average Volume Assured Pressure Support) Mode in COPD Patients with Respiratory Failure
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GÜLEÇ BALBAY, Ege, primary, AYTEKİN, Fuat, additional, BALBAY, Öner, additional, ANNAKKAYA, Ali Nihat, additional, and ARBAK, Peri, additional
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- 2018
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84. Waterpipe (narghile, hookah) tobacco smoking-induced acute eosinophilic pneumonia
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Balbay, EgeGüleç, primary, Annakkaya, AliNihat, additional, Öztürk, Özlem, additional, Önal, Binnur, additional, Aytekin, Fuat, additional, and Balbay, Öner, additional
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- 2018
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85. A 37-Year-Old Asymptomatic Male Case of Mass Lesion in the Right Upper Zone detected on Chest x-Ray: What is your Diagnosis?
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Fatih Alasan, Elif Nisa Unlu, and Ali Nihat Annakkaya
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Mass/lesion ,medicine.medical_specialty ,lcsh:Internal medicine ,business.industry ,medicine ,Radiology ,medicine.symptom ,business ,lcsh:RC31-1245 ,Asymptomatic - Abstract
Annakkaya, Ali Nihat N/0000-0002-7661-8830 WOS: 000359777000013 …
- Published
- 2015
86. Serum Oxidant and Antioxidant Levels in Diesel Exposed Toll Collectors
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Peri Arbak, Oner Balbay, Neslihan Bukan, Özlem Yavuz, Füsun Ülger, Ali Nihat Annakkaya, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, BAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Arbak, Peri, Yavuz, Özlem, Balbay, Öner, and Annakkaya, Ali Nihat
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Adult ,Male ,medicine.medical_specialty ,Antioxidant ,Turkey ,MDA ,medicine.medical_treatment ,Nitrite+Nitrate ,Nitric Oxide ,medicine.disease_cause ,Toll Collectors ,Pulmonary function testing ,chemistry.chemical_compound ,Nitrate ,Malondialdehyde ,Occupational Exposure ,Internal medicine ,medicine ,Humans ,Vitamin E ,Nitrite ,Respiratory system ,Nitrites ,Vehicle Emissions ,Occupation ,Nitrates ,business.industry ,Smoking ,Public Health, Environmental and Occupational Health ,Diesel Exhaust ,Respiratory Function Tests ,Oxidative Stress ,Cross-Sectional Studies ,Endocrinology ,chemistry ,Case-Control Studies ,Immunology ,Lipid Peroxidation ,business ,Oxidative stress - Abstract
WOS:000223257800005 PubMed: 15308827 Serum Oxidant and Antioxidant Levels in Diesel Exposed Toll Collectors: Peri ARBAK, et al. Department of Chest Diseases, Abant Izzet Baysal University, Duzce School of Medicine, Turkey-it has been suggested that exposure to diesel exhaust may lead to adverse effects due to the generation of oxidants. To evaluate the end products of oxidative stress in DE exposure, toll collectors who are considered a high risk group in regard to occupational toxins were compared to controls who had office-based occupations in the same company in this cross sectional study. A total of 38 toll collectors constituted the study group. All subjects were male. The toll collectors and 29 controls were similar regarding age, smoking status and duration of work. All subjects underwent a clinical examination and an interviewer-administrated questionnaire regarding respiratory symptoms, past medical and occupational history, and pulmonary function tests were performed in all subjects. Serum malondialdehyde (MDA), nitrite+nitrate and vitamin E levels were measured. Toll collectors showed higher serum MDA (5.76 +/- 2.15 mumol/L vs. 3.07 +/- 0.76 mumol/L, p=0.0001) and nitrite+nitrate levels (96.50 +/- 45.54 mumol/L vs. 19.32 +/- 11.77 mumol/L, p=0.0001) than controls. Vitamin E levels were similar in toll collectors and controls (10.57 +/- 3.44 mg/L and 9.72 +/- 2.44 mg/L, respectively, p=0.267). There was no difference between groups in terms of the findings of clinical examinations and respiratory symptoms. In pulmonary function parameters, only peak expiratory flow (PEF) in toll collectors was significantly lower than that of controls (88.9% predicted and 104.2% predicted, respectively, p=0.012). In conclusion, we suggest that serum MDA and nitrite+nitrate levels may be used as biological markers of oxidative stress related to DE exposure, but prospective controlled clinical studies are necessary to clarify the possible association between concentrations of MDA and nitrite+nitrate and pulmonary diseases related to DE exposure.
- Published
- 2004
87. Respiratory symptoms and pulmonary functions in hazelnut workers
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Arbak, Peri Meram, Karataş, Naciye, Balbay, Ege Güleç, Pak, Salih, Balbay, Öner Abidin, Annakkaya, Ali Nihat, Özşahin, Sefa L., [Ozsahin, Sefa L.] Cumhuriyet Univ, Dept Chest Dieases, Sch Med, Sivas, Turkey -- [Arbak, Peri -- Karatas, Naciye -- Balbay, Ege Gulec -- Pak, Salih -- Balbay, Oner -- Annakkaya, Ali Nihat] Duzce Univ, Dept Chest Dieases, Sch Med, Duzce, Turkey, Annakkaya, Ali Nihat N -- 0000-0002-7661-8830, and Balbay, Ege -- 0000-0002-1557-7019
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pulmonary functions ,Hazelnut workers - Abstract
WOS: 000287819600022, Introduction: To investigate the effects of hazelnut exposure on pulmonary functions in a cross-sectional study on hazelnut processing workers. Materials-methods: One hundred fifty hazelnut workers (137 females and 13 males), and seventy controls (63 females and 7 males) were included. A questionnaire regarding the respiratory symptoms was given to all subjects. Standard pre-shift and post-shift forced expiratory pulmonary functions were obtained from all participitants by spirometry. Furthermore, dust particles were measured according to their sizes. Results: The occurences of common respiratory complaints as cough (8%) and dyspnea (6%) were significantly higher in hazelnut workers than the controls (p=0.009 and p=0.029, respectively). Both of the pre-shift and post-shift spirometric values of hazelnut workers were significantly lower than those of controls. Post-shift FVC (2738.9 +/- 652.2) was significantly lower than pre-shift FVC (2765.8 +/- 634.8) in hazelnut workers (p=0.024). Nine hazelnut (6.0%) workers have shown a decrease of more than 10% in post shift FEV 1 whereas none of the controls have had abnormal decrease in post shift values (p=0.060). Conclusion: A significant deterioration in both restrictive and obstructive pulmonary functions was observed in hazelnut workers. Preventive measures against dusty workplaces should be undertaken to protect the respiratory health of hazelnut workers.
- Published
- 2011
88. Extrapulmonary involvement in patients with sarcoidosis in Turkey
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Gulfer, Okumus, Benan, Musellim, Erdogan, Cetinkaya, Hatice, Turker, Esra, Uzaslan, Esin, Yenturk, Oguz, Uzun, Leyla, Saglam, Ozlem Ozdemir, Kumbasar, Gokhan, Celik, Ali Nihat, Annakkaya, Gundeniz, Altiay, Levent, Tabak, Aysin, Sakar, Goksel, Kiter, Serdar, Erturan, Haluk, Turktas, Enver, Yalniz, Atilla, Akkoclu, Candan, Ogus, Omer Tamer, Dogan, Metin, Ozkan, Serir, Aktogu, Isil, Uzel, Gul, Ongen, [Okumus, Gulfer -- Tabak, Levent] Istanbul Univ, Istanbul Fac Med, Dept Pulm Dis, Istanbul, Turkey -- [Musellim, Benan -- Erturan, Serdar -- Ongen, Gul] Istanbul Univ, Cerrahpasa Med Fac, Dept Pulm Dis, Istanbul, Turkey -- [Cetinkaya, Erdogan -- Yenturk, Esin] Yedikule Chest Dis & Chest Surg Educ & Res Hosp, Istanbul, Turkey -- [Turker, Hatice] Sureyyapasa Training & Res Hosp Chest Dis & Thora, Istanbul, Turkey -- [Uzaslan, Esra] Uludag Univ, Fac Med, Chest Dis Dept, Bursa, Turkey -- [Uzun, Oguz] Ondokuz Mayis Univ, Dept Pulm Med, Fac Med, Samsun, Turkey -- [Saglam, Leyla] Ataturk Univ, Dept Chest Dis, Fac Med, Erzurum, Turkey -- [Kumbasar, Ozlem Ozdemir -- Celik, Gokhan] Ankara Univ, Fac Med, TR-06100 Ankara, Turkey -- [Turktas, Haluk] Gazi Univ, Sch Med, Dept Pulm Med, Ankara, Turkey -- [Annakkaya, Ali Nihat] Abant Izzet Baysal Univ, Dept Chest Dis, Fac Med, Duzce, Turkey -- [Altiay, Gundeniz] Trakya Univ Hosp, Dept Chest Dis, Edirne, Turkey -- [Sakar, Aysin] Celal Bayar Univ, Dept Pulmonol, Fac Med, Manisa, Turkey -- [Kiter, Goksel] Pamukkale Univ, Dept Pulm Dis, Fac Med, Denizli, Turkey -- [Yalniz, Enver -- Aktogu, Serir] Dokuz Eylul Univ, Fac Med, Dept Chest Dis, Izmir Training & Res Hosp Chest Dis & Thorac Surg, Izmir, Turkey -- [Akkoclu, Atilla] Dokuz Eylul Univ, Dept Chest Dis, Sch Med, Izmir, Turkey -- [Ogus, Candan] Akdeniz Univ, Sch Med, Dept Resp Dis, TR-07058 Antalya, Turkey -- [Dogan, Omer Tamer] Cumhuriyet Univ, Dept Chest Dis, Fac Med, Sivas, Turkey -- [Ozkan, Metin] Gulhane Mil Med Acad, Dept Chest Dis, Ankara, Turkey -- [Uzel, Isil] Instanbul Vatan Hosp, Istanbul, Turkey, and Annakkaya, Ali Nihat N -- 0000-0002-7661-8830
- Subjects
Male ,myalgia ,Eye Diseases ,Turkey ,kidney disease ,diarrhea ,gastrointestinal symptom ,eye disease ,medical record review ,Turkey (republic) ,bone pain ,cardiovascular disease ,erythema nodosum ,Prevalence ,Prospective Studies ,xerostomia ,adult ,Incidence ,article ,skin defect ,clinical epidemiology ,lymph node ,Middle Aged ,eye ,Arthralgia ,backache ,female ,arthritis ,priority journal ,sweating ,joint swelling ,Female ,neck tumor ,headache ,Adult ,skin ,Sarcoidosis ,dyspepsia ,neurological complication ,Skin Diseases ,lung ,range of motion ,lung sarcoidosis ,paresthesia ,hepatomegaly ,lymphadenopathy ,Humans ,human ,sarcoidosis ,extrapulmonary involvement ,dizziness ,splenomegaly ,major clinical study ,multicenter study ,Back Pain ,heart palpitation ,Lymph Nodes ,parotid gland - Abstract
WOS: 000288959600009, PubMed ID: 20946338, Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group. New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 +/- 12 years) had extrapulmonary involvement in this study (40.6%). The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis (P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients, and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years (P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population.
- Published
- 2011
89. Does hiatal hernia cause bronchiectasis?
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Ege Gulec Balbay, Elif Nisa Unlu, Mehmet Kos, Alp Alper Safak, Oner Balbay, and Ali Nihat Annakkaya
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Thorax ,medicine.medical_specialty ,Bronchiectasis ,medicine.diagnostic_test ,business.industry ,Incidence (epidemiology) ,Computed tomography ,Mean age ,medicine.disease ,digestive system diseases ,Hiatal hernia ,medicine ,Etiology ,Radiology ,Differential diagnosis ,business - Abstract
We aimed to investigate the incidence of bronchiectasis supposed to be created by the compression hiatal hernia (HH) on bronchi. The thorax computed tomography (CT) scans of patients which carried out in Duzce University, School of Medicine, between February 2014 and August 2015 were retrospectively evaluated. The repeated scans in the same patient were excluded. 4388 patients were included in the study. A total of 98 HH cases were detected. The rate of HH according to small, moderate and large, size were 45 (45.9%), 9 (9.2 %), 44 (44.9), respectively. 58 of the cases (59.2%) were female. The mean age was 73.30 ± 9.14 (45-90). 9 (9, 1) patients (8 female, %88.8) were found to have confirmed bronchiectasis on Thorax CT. The rate of hiatal hernia accompanied by bronchiectasis were similar in male and female gender (p = 0.078). The prevalence of bronchiectasis were significantly high in large hernias with 81.4% rate (p = 0.009). Demographic parameters and comparisons between Bronchiectasis+, Bronchiectasis– subgroups are shown in Table 1. Bronchiectasis rate, was 12.343 times (OR: 12.343, 95% CI: 1.479-103.027, p = 0.009) higher in large HH group compared to small and moderate HH group .Hiatal hernia accompanied by bronchiectasis with 88.1% was anatomically near to HH. As a result, it is thought that hiatal hernia may cause bronchiectasis due to external compression other than lymphadenopathy or the tumor as an etiology of bronchiectasis and should be considered in the differential diagnosis.
- Published
- 2016
90. Epidemiological features of Turkish patients with sarcoidosis
- Author
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Aysin Sakar, Metin Ozkan, Haluk Turktas, S. Aktogu, H. Turker, Gündeniz Altiay, Omer Tamer Dogan, Atilla Akkoçlu, Levent Tabak, Erdoğan Çetinkaya, Gulfer Okumus, Esra Uzaslan, Oguz Uzun, Işıl Uzel, Serdar Erturan, Gökhan Çelik, Ali Nihat Annakkaya, G. Ongen, Özlem Özdemir Kumbasar, Leyla Saglam, Esin Yentürk, Göksel Kiter, E. Yalniz, Benan Musellim, Candan Öğüş, [Musellim, B. -- Ongen, G. -- Erturan, S.] Istanbul Univ, Dept Pulm Dis, Cerrahpasa Med Fac, Istanbul, Turkey -- [Kumbasar, O. O. -- Celik, G.] Ankara Univ, Fac Med, TR-06100 Ankara, Turkey -- [Cetinkaya, E. -- Yenturk, E.] Educ & Res Hosp, Yedikule Chest Dis & Chest Surg, Istanbul, Turkey -- [Turker, H.] Sureyyapasa Training & Res Hosp Chest Dis & Thora, Istanbul, Turkey -- [Uzaslan, E.] Uludag Univ, Fac Med, Chest Dis Dept, Bursa, Turkey -- [Uzun, O.] Ondokuz Mayis Univ, Dept Pulm Med, Fac Med, Dept Pulm Med, Samsun, Turkey -- [Saglam, L.] Ataturk Univ, Fac Med, Dept Chest Dis, Erzurum, Turkey -- [Okumus, G. -- Tabak, L.] Istanbul Univ, Dept Pulm Dis, Istanbul Fac Med, Istanbul, Turkey -- [Annakkaya, A. N.] Abant Izzet Baysol Univ, Fac Med, Dept Chest Dis, Duzce, Turkey -- [Altiay, G.] Trakya Univ Hosp, Dept Chest Dis, Edirne, Turkey -- [Sakar, A.] Celal Bayar Univ, Fac Med, Dept Pulmonol, Manisa, Turkey -- [Kiter, G.] Pamukkale Univ, Fac Med, Dept Pulm Dis, Denizli, Turkey -- [Turktas, H.] Gazi Univ, Sch Med, Dept Pulm Med, Ankara, Turkey -- [Yalniz, E. -- Aktogu, S.] Izmir Training & Res Hosp Chest Dis & Thorac Surg, Dept Chest Dis, Fac Med, Izmir, Turkey -- [Akkoclu, A.] Dokuz Eylul Univ, Sch Med, Dept Chest Dis, Izmir, Turkey -- [Ogus, C.] Akdeniz Univ, Sch Med, Dept Resp Dis, TR-07058 Antalya, Turkey -- [Dogan, O. T.] Cumhuriyet Univ, Fac Med, Dept Chest Dis, Sivas, Turkey -- [Ozkan, M.] Gulhane Mil Med Acad, Dept Chest Dis, Ankara, Turkey -- [Uzel, I.] Istanbul Vatan Hosp, Istanbul, Turkey, Annakkaya, Ali Nihat N -- 0000-0002-7661-8830, Ondokuz Mayıs Üniversitesi, Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı., Uzaslan, Esra, and AAI-1004-2021
- Subjects
Male ,Systemic disease ,Cardiac & cardiovascular systems ,Turkey ,Epidemiology ,epidemiological data ,United-states ,cigarette smoking ,Sarcoidosis ,Propionibacterium Acnes ,Granuloma ,Disease ,Turkey (republic) ,Rochester ,Familial sarcoidosis ,Prevalence ,Personnel ,Mass Screening ,Young adult ,familial disease ,Aged, 80 and over ,Smoking ,article ,Middle Aged ,Lymphatic disease ,Risk-factors ,female ,priority journal ,Female ,onset age ,Adult ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Adolescent ,Minnesota ,sex difference ,Respiratory system ,Young Adult ,Sarcoidosis, Pulmonary ,Lung-diseases ,Internal medicine ,medicine ,Tuberculosis ,Humans ,controlled study ,human ,First-degree relatives ,Mass screening ,Aged ,business.industry ,medicine.disease ,major clinical study ,Surgery ,Cardiovascular system & cardiology ,Isle-of-man ,incidence ,Epidemiologic Methods ,business - Abstract
WOS: 000266684100017, PubMed ID: 19181507, Epidemiological characteristics of sarcoidosis differ according to geographical distribution. The aim of our study was to disclose epidemiological characteristics in our country. The data was collected from investigators, who sent information on newly-diagnosed patients via internet. In 2 years 198 female and 95 mate patients were enrolled to the study (f/m:2.08). Mean age of patients was 44 +/- 13 years (17-90). Mean age of mate patients was 38 12 while mean age of female patients was 48 13 (p < 0.001). 73.4% of patients were nonsmokers (85.4% of females; 48.4% of mates; (p < 0.001)). About 50% of our 293 patients were housewives. Familial sarcoidosis was found in 3 patients' first degree relatives. Estimated annual incidence of sarcoidosis for Turkey was calculated as 4 per 100,000 person. According to our study, 2/3 of sarcoidosis patients were women; mean age of patients was 45 and the disease began 10 years later in female patients. 80% of patients were nonsmokers; negative relation between sarcoidosis and smoking was evident especially in women. Familial sarcoidosis frequency was lower compared to other studies in the literature. There was no occupational exposure history in our patients. Our incidence rate, is similar with the results of other European studies. (C) 2008 Elsevier Ltd. All rights reserved.
- Published
- 2009
91. An Unusual Aspiration: Tracheo-esophageal Voice prosthesis
- Author
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Mete Erbas, Ali Nihat Annakkaya, Ege Gulec Balbay, and Özcan Yıldız
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Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,business.industry ,medicine ,Tracheo-esophageal ,Voice prosthesis ,business ,Surgery - Published
- 2012
92. Serum IgE Antibodies against Hazelnut in Hazelnut Processing Workers
- Author
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Songül Binay, Ali Nihat Annakkaya, Peri Arbak, Ümran Toru, Naciye Karatas, Ege Gulec Balbay, Özlem Yavuz, Oner Balbay, and Tıp Fakültesi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Allergy ,Respıratory Symptoms ,Article Subject ,Adolescent ,lcsh:Medicine ,Immunoglobulin E ,lcsh:Technology ,General Biochemistry, Genetics and Molecular Biology ,Serum ige ,Exposure ,Pulmonary function testing ,Young Adult ,Corylus ,Occupational Exposure ,Internal medicine ,medicine ,Humans ,Respiratory system ,lcsh:Science ,Sensitization ,General Environmental Science ,Asthma ,biology ,lcsh:T ,business.industry ,lcsh:R ,General Medicine ,Middle Aged ,medicine.disease ,Respiratory Function Tests ,Occupational Diseases ,medicine.anatomical_structure ,Immunology ,biology.protein ,Lung-Functıon ,lcsh:Q ,Female ,Antibody ,business ,Research Article - Abstract
Yavuz, Özlem (Balikesir Author), Aim. Previous studies have shown a higher sensitization rate to hazelnut in processing workers but no relation was found between the respiratory symptoms in workplace and hazelnut sensitization. Material and Method. To evaluate the association between the hazelnut sensitization and workplace-related respiratory complaints, hazelnut processing workers had undergone a questionnaire included work-related respiratory symptoms, smoking history, pulmonary function testing, and measurement of serum IgE antibodies against hazelnut. Results. This study consisted of 88 hazelnut processing workers (79 females and 9 males), aged 14-59 years (Mean +/- SD: 33.8 +/- 10.5 years). The mean working duration was 38.8 +/- 36.6 months (min: 1-max: 180). Specific IgE against hazelnut allergens was positive in 14 of cases (17.1%). There was no significant difference between the cases with and without specific IgE against hazelnut allergens regarding respiratory symptoms, history of allergy, smoking status and spirometric values. Conclusion. 17.1% of the hazelnut processing workers were seropositive against hazelnut. Being sensitized to hazelnut was not found to be associated with work-related respiratory symptoms in this study. Further studies are needed in hazelnut workers respiratory health to search topics other than asthma.
- Published
- 2012
93. Akciğer Kanserlerine Eşlik Eden Plevra Sıvısı
- Author
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KARATAŞ, Naciye, GÜLEÇ, Ege, TORU, Ümran, ARBAK, Peri, and ANNAKKAYA, Ali Nihat
- Subjects
Akciğer kanseri,plevra sıvısı ,respiratory system ,Lung cancer,pleural effusion ,respiratory tract diseases - Abstract
İt has been known that prognosis is poor in lung cancer vvith pleural effusion. The records of 44 lung cancer patients vvith pleural effusion admitted to our clinic betvveen 2003-2009 were evaluated. Thirty nine patients (88.6%) were male and five of them were (11.4%) femaie. Mean age of patients was 62.8 ± 11.7 (minimum 36-maximum 93) years. Thirty three patients (75.0%) were diagnosed as non small celi lung cancer (NSCLC) whereas remaining (25.0%) were presented as small celi lung cancer. Most of the cases (16/33) were diagnosed as sçuamous celi cancer in patients vvith NSCLC vvhereas the remaining were ade-nocarcinoma (seven cases), large celi cancer (two cases) and non-classified NSCLC (eight cases). The stages in most of the cases were presented as T4 (43.2%), N1 (27.3%), MO (43.2%) and stage (36.4%). Pleural effusion was in right side (43.2%) and minimal (45.5%) in size in the majority of cases. Most of the pleural effusions were in the same side vvith tumor (88.6%>), were exudative (61.4%>) and were not evaluated microscopically (61.4%). The ratio of the patients undement chemotherapy and presented vvith regression in pleural effusion was high after the first course then it decreased in the later courses (39.1 %> -»9.1 %>). The ratio of patients vvhose effusions remained stable after the first course increased in the later courses and remained above 50% (56.6%> -»63.6%>). The ratio of patients vvith Progressive pleural effusions increased in the later courses (4.3%> ->27.3%o). İn conclusion; pleural effusion might be mostly seen in the later stages of lung cancer. Most of the pleural effusions were minimal and located at the same side vvith tumor. The regression response that was achieved in the first course of chemotherapy decreased in the later courses. Progression in pleural effusions increased in the later courses., Plevra sıvısının eşlik ettiği akciğer kanseri tablosunda prognozun sıklıkla kötü olduğu bilinmektedir. Kliniğimizde 2003-2009 yılları arasında görülmüş plevra sıvısının eşlik ettiği 44 akciğer kanseri hastasının kayıtları değerlendirildi. Olguların 39 (%88.6)'u erkek, 5 (%11.4)'i kadındı. Olguların yaş ortalaması 62.8 ± it.7 (36-93) idi. Küçük hücreli dışı akciğer kanseri (KHDAK) tamlı olgu sayısı 33 (%75.0) iken, küçük hücreli akciğer kanseri tamlı olanların sayısı 11 (%25.0) idi. KHDAK olgularının çoğunluğunu (16 olgu) yassı hücreli akciğer Ca oluştururken, kalanları (yedi olgu) adenokanser, büyük hücreli (iki olgu) ve tiplendirilememiş (sekiz olgu) idi. Olguların çoğunlukla T4 (%43.2), N1 (%27.3), MO (%43.2) ve evre 4 (%36.4) dağılımına uyduğu gözlendi. Olguların plevra sıvısı sıklıkla sağ akciğerde (%43.2), minimal (%45.5), kitle ile aynı tarafta (%88.6), eksüda içeriğinde (%61.4), mikroskobik olarak direkt muayene ile değerlendirilmemişti (%61.4). Kemoterapi uygulanan ve sıvıda regresyon gözlenen olguların oranı ilk kürde yüksek iken sonraki kürlerde azaldı (%39.1 -» %9.1). Plevra sıvısı stabil kalan olguların oranı ilk kürden itibaren artarak tüm kürlerde %50'nin üstünde seyretti (%56.6 -> %63.6). Plevra sıvısında progresyon gözlenen olguların oranı ilk kürden son kürlere giderek artış gösterdi (%4.3 -> %27.3). Sonuçta; akciğer kanserlerinde plevra sıvısının daha sıklıkla ileri evrelerde izlenebildiği, olguların çoğunun minimal sıvılı olduğu ve kitle ile sıvının aynı tarafta yer aldığı gözlendi, ilk kürde sağlanan sıvıda regresyon yanıtının diğer kürlerde azaldığı ve sıvıda progresyon oranının ilerleyen kürlerde arttığı gözlendi.
- Published
- 2015
94. Extrapulmonary involvement in patients with sarcoidosis in Turkey
- Author
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Candan Öğüş, Omer Tamer Dogan, Gökhan Çelik, Levent Tabak, Gulfer Okumus, Özlem Özdemir Kumbasar, Ali Nihat Annakkaya, Işıl Uzel, Aysin Sakar, Erdoğan Çetinkaya, Esra Uzaslan, Oguz Uzun, Serdar Erturan, Göksel Kiter, Metin Ozkan, Haluk Turktas, Esin Yentürk, Gündeniz Altiay, Enver Yalniz, Leyla Saglam, Benan Musellim, H. Turker, Atilla Akkoçlu, Serir Aktogu, and G. Ongen
- Subjects
Pulmonary and Respiratory Medicine ,Turkish population ,medicine.medical_specialty ,business.industry ,Incidence (epidemiology) ,medicine.disease ,Surgery ,Concomitant ,Internal medicine ,Back pain ,Medicine ,Organ involvement ,In patient ,Sarcoidosis ,medicine.symptom ,business ,Prospective cohort study - Abstract
Background and objective: Extrapulmonary sarcoidosis is common, and is almost always associated with concomitant thoracic involvement. Extrapulmonary manifestations vary on the basis of gender, age at presentation and ethnicity. The aim of this study was to investigate extrapulmonary involvement in patients with sarcoidosis in Turkey. Methods: This study was conducted by Turkish Thoracic Society Clinical Problems Study Group. New cases of sarcoidosis between 1 June 2004 and 31 May 2006 were recorded on electronic case record forms sent to all potential investigators and information about extrapulmonary involvement was collected. Results: One hundred and nineteen of 293 patients (83 female, 36 male, mean age = 45 ± 12 years) had extrapulmonary involvement in this study (40.6%). The median time to diagnosis was 6 months and this was longer than patients with just thoracic sarcoidosis (P = 0.001). Extrapulmonary symptoms were present in 181 (61.8%) patients, and skin lesions, arthralgia and back pain were the commonest (33.4%, 20.8% and 16.4%, respectively). Incidence of organ involvement was independent of age with the exception of ocular involvement, which was higher in those under the age of 40 years (P = 0.007). Conclusions: Skin and peripheral lymph node involvement were the most common sites of extrapulmonary involvement and ocular involvement was more common in those under the age of 40 years in patients with sarcoidosis in a Turkish population.
- Published
- 2011
95. Effect of symptom-to-treatment interval on prognosis in lung cancer
- Author
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Oner Balbay, Ismet Bulut, Mete Erbas, Peri Arbak, Cahit Bilgin, Ali Nihat Annakkaya, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Annakkaya, Ali Nihat, Arbak, Peri, Balbay, Öner, Bilgin, Cahit, Erbaş, Mete, Bulut, İsmet, Annakkaya, AN, Arbak, P, Balbay, O, Bilgin, C, Erbas, M, Bulut, I, and Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü
- Subjects
Adult ,Male ,Cancer Research ,medicine.medical_specialty ,symptom-to-treatment interval ,Lung Neoplasms ,Time Factors ,Referral ,Disease ,Disease-Free Survival ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Carcinoma, Non-Small-Cell Lung ,Health care ,Medicine ,Humans ,Stage (cooking) ,Carcinoma, Small Cell ,Intensive care medicine ,Lung cancer ,Survival analysis ,Aged ,Neoplasm Staging ,Aged, 80 and over ,Performance status ,Symptom-to-treatment Interval ,business.industry ,Tumor Stage ,Lung Cancer ,Cancer ,General Medicine ,Middle Aged ,medicine.disease ,Prognosis ,Survival Analysis ,respiratory tract diseases ,lung cancer ,Oncology ,030220 oncology & carcinogenesis ,Physical therapy ,Female ,business ,tumor stage - Abstract
Aims and backgroundTo evaluate the relationship between delayed diagnosis and the degree of invasion and survival in lung cancer.MethodsOne hundred and three patients (96 men) with lung cancer were included. Stages in the diagnosis of lung cancer were classified as follows: symptom-to-doctor interval, i.e., the interval from the first symptoms related to the presence of lung cancer to the first consultation with a medical professional; doctor-to-diagnosis interval, i.e., the interval between the first medical visit and confirmation of the diagnosis; and diagnosis-to-treatment interval, i.e., the interval between diagnosis and complete TNM staging and treatment. The symptom-to-treatment interval (STI) was the sum of the 3 intervals. The degree of invasion was determined by the TNM classification.ResultsThe patients were followed up for a mean period (± SD) of 7.4 ± 8.7 months. Seventy-six (74%) patients were diagnosed with non-small cell lung cancer (NSCLC) and 27 patients (26%) with small cell lung cancer (SCLC). The mean length of STI was 120 ± 101 days (median, 90). The mean length of the symptom-to-doctor interval was 63 ± 62 days (median, 45), while the doctor-to-diagnosis and diagnosis-to-treatment intervals were 41 ± 82 days (median, 10) and 16 ± 12 days (median, 12), respectively. When the STIs of the patients were correlated with tumor stage, tumor invasion, lymph node involvement and metastasis, no significant differences were found. Patients with an STI longer than 60 days had a significantly longer survival. Regarding the type of lung cancer and STI, the median survival was shorter in patients with an STI of less than 60 days both in NSCLC and SCLC, although this was not statistically significant in SCLC.ConclusionsThe shorter the diagnostic interval, the shorter was the median survival in our study. The reason for the apparent discrepancy between poor prognosis of lung cancer patients in spite of early diagnosis might be much faster progression of the disease itself.
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- 2007
96. Pulmonary functions, respiratory complaints and radiographic findings in aluminium foundry workers
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Bilgin, Cahit, primary, Arbak, Peri, additional, Ünlü, Elif Nisa, additional, Güleç Balbay, Ege, additional, Balbay, Öner, additional, Annakkaya, Ali Nihat, additional, and Akdoğan, Mehmet, additional
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- 2017
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97. Respiratory symptoms and peak expiratory flow rates among furniture-decoration students
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Arbak, P., Bilgin, C., Balbay, O., Yeşildal, N., Ali Nihat Annakkaya, Ulger, F., Arbak, P, Bilgin, C, Balbay, O, Yesildal, N, Annakkaya, AN, Ulger, F, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Bilgin, Cahit, BAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Arbak, Peri, Balbay, Öner, Yeşildal, Nuray, and Annakkaya, Ali Nihat
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Peak Expiratory Flow ,Furniture Production ,Occupational Asthma ,peak expiratory flow ,furniture production ,occupational asthma - Abstract
Annakkaya, Ali Nihat N/0000-0002-7661-8830; BILGIN, CAHIT/0000-0003-2213-5881 WOS: 000222523400003 PubMed: 15236493 This study was designed to evaluate the effects of furniture production, mainly including fir tree (aberia mulleriana), on respiratory health of young workers and to compare the results with those obtained from previous Studies. Sixty-four furniture-decoration students (57 males and 7 females) and 62 controls (54 male, 8 female) from different departments in the same school were included into the Study. All participants were assessed with a questionnaire (concerning history of occupational exposure, work-related respiratory and other symptoms, smoking history, previous asthma history), full physical examination, spirometric evaluation and chest radiograph. Participants then performed serial monitoring of peak expiratory flow rates (PEER) at work and away from work within a month. Mean age of students was 20.9 +/- 3.7 years, 20.5 +/- 2.6 years in controls. There was no difference between study and control groups with regard to age, gender, smoking status and previous asthma history. Reported cough (23.4% vs. 8.1%) and shortness of breath (18.8% vs. 6.5%) were significantly higher in furniture-decoration students than in controls (p = 0.016 and p = 0.034, respectively). Furniture-decoration students had higher conjunctivitis (34.4% vs. 9.7%, p = 0.001) and rhinitis (34.4% vs. 19.4%, p = 0.044) history when compared with controls. Both students and controls were normal in terms of respiratory examination. PEF recordings were performed for approximately one month. Diurnal variability greater than 20% was seen in 12/64 (18.7%) of students at work, whereas it was detected in 4/62 (6.4%) of controls (p = 0,034). When comparing for the presence of diurnal variability greater than 20% in weekends, no difference was found between groups (p = 0.457). In conclusion, early detection of work-related respiratory changes by serial monitoring of peak expiratory flows should save the workers from hazardous respiratory effects of the furniture production, especially in young population.
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- 2004
98. Evalation of smoking prevelance in Turkey after tobacco control strategies
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Feyza Sariguzel, Davut Baltaci, Fatih Alasan, Ali Nihat Annakkaya, Usame Velioglu, Handan Ankarali, and Leyla Yilmaz Aydin
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medicine.medical_specialty ,Turkish population ,Epidemiology ,business.industry ,Public health ,medicine.medical_treatment ,Smoking ,Tobacco control ,Prevalence ,Primary care ,Population based study ,Environmental health ,Medicine ,Smoking cessation ,business ,Female population - Abstract
The smoking is main public health problem and requires profound struggle. Turkey was one of the leader countries in tobacco control. Aim: To investigate the prevalence of smoking among Turkish population after tobacco control strategies begun. Methods: Population survey and population based study conducted in primary care settings with face to face interview. The study results were preliminary. It has been conducted since May 2014 and will end up May 2015. Result: The study enrolled a total of 1287 subjects (M: 38.9% and F: 61.1%) with mean age of 45 years-old (14-88). The ratio of current smokers was 21.1% (14.6% among women and 31.2% among men, p Conclusions: The present study reveals the current information about smoking in Turkey. Smoking prevalence was still higher, particularly among male population. The majority of male young population was comparatively smokers. Among female population, whether having or not a chronic disease seemed to be not influential on smoking cessation.
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- 2015
99. Evalaution of smoking frequency and smoking cessation training among Turkish family physicians
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Usame Velioglu, Handan Ankarali, Leyla Yilmaz Aydin, Fatih Alasan, Ali Nihat Annakkaya, Davut Baltaci, and Feyza Sariguzel
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Public health ,medicine.medical_specialty ,Epidemiology ,business.industry ,Turkish ,medicine.medical_treatment ,Significant difference ,Gate-keeper ,Mean age ,Primary care ,Smoking prevalence ,language.human_language ,Family medicine ,medicine ,language ,Smoking cessation ,business ,Male to female - Abstract
Smoking is main problem among family physicians. They are gate keeper and role model for their patients. Aim: To evaluate the prevalence of smoking among Turkish family physicians and smoking cessation training. Methods: The cross-sectional and primary care based study was has been conducted since May 2014 and will be completed in May 2015. The primary care-based survey was applied in face to face interview to family physicians. Results: The study enrolled 261 physicians (mean age of 46 years-old). Male to female ratio was 95/166. The frequency of current smokers was 29.1%. The ratio of current smokers among male to female physicians was significantly high (37.3% versus 14.7%; p Conclusion: The preliminary study revealed that the smoking prevalence was quite high and comparatively higher among male than female. The significant difference was more marked under age of 50. Pre-and post-graduate training on smoking cessation among family physicians seemed to be not satisfactory.
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- 2015
100. Büyük Havayolu Obstrüksiyonuna Neden Olan Bir Trakeo-bronkopati Osteokondroplastika Olgusu
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N, Akın, Akın, Neşe, Dumlu, Talha, Balbay, Ege Güleç, Yıldırım, Ümran, Karataş, Naciye, Küçük, Ebru, and Annakkaya, Ali Nihat
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Trakeopati Bronkoskopi Kelimeler: Trakeobronkopati Büyük Osteokondroplastica,Osteoplastika,Havayolu Obstrüksiyonu - Published
- 2015
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